$380 Thursday, November 10, 2005 Poster Abstracts

differences. However, it is not known whether these assessments are accurate or meaningful. Synchiria, or feeling bilateral touch following ruff lateral stimulation, has been reported post-stroke, but its frequency has not been reported. Method: We undertook standard quantitative and qualitative sensory assessments in sixty early post-stroke patients to determine (i) the frequency of synchiria, (ii) the accuracy of patients" perception of sensory deficits, and (iii) qualitative and quantitative sensory assess- ments o f light touch, pressure-pain thresholds and thermal thresholds. Results: Our results to date suggest that (1) ~65% of patients denton- strate synclffria, (2) .~80% of patients are unaware of their sensory deficits, (13) there is an ~25% accuracy of determining any post- stroke sensory deficits with a clinical test for light touch, (4) ~75% of patients are hypersensitive to light touch and have decreased pressure- pain thresholds temperature on the affected side, and, (5) ~90% of patients have > 30% discrepancy in affected-to-mtaffected pressure- pain threshold testing. Conclusion: Data characterising post-stroke sensory changes will be presented and their potential clinical relevance discussed.

1096 Early clitfical and CT predictors of poor outcome in Non-Lacunar MCA Infarcts in a tertiary hospital

Agcopra, A t, Adapon, B 2, Jamora, RD a. e Univeysity of the Philippines-Philippine General Hospital, iVlanila, Philippines; 2Computerized Imaging Institute, Makati iVlediea[ Cotter, Makati City, Philippines

Backgroumh Early prediction of acute stroke outcomes especially in those with middle cerebral artery territory infarcts can play an important role in prognosis and implementation of rational interven- tions. The baseline demographic data and preexisting conditions of patients, and characteristics of cranial CI" scans previously identified as possible criteria for infarct severity were analyzed to detet~fine predictors of severe disability on discharge or death (MRS > 4). Method: Data from patients of the Hemicraniectomy for Malignant M C A Infarcts (HeMMI) study admitted between September 2002 to August 2003 not subjected to neurosurgical intervention were ana- lyzed. Included were subjects undergoing cranial CT scanning within 48 hours of stroke onset. Early neuroradiologic parameters were assessed in a case-control design. CT scans were interpreted for stroke- related abnommlities by three blinded independent neuroradiologists using standardized coding. Results: Of the 80 patients initially enrolled into the HeMMI study, 38 qualified for inclusion. 18 o f the patients either had severe disability on discharge rendering them bedridden requiring constant nursing care and assistance in ADL s or subsequently died during hospital stay (MRS - 5 6). 20 patients with MRS < 4 on discharge were identified as controls. From the data gathered, univariate analysis revealed atrial fibrillation (OR, 7.1; 95% CI, 1.6-30.6; P - 0.02), NIHSS scores _>22 (OR, 7.5; 95% CI, 1.8-32.1; P - 0.01) and GCS _< 8 (OR, 4.5; 95% CI, 1.1 19.5; P -- 0.046) were associated with very severe disability at discharge or death (MRS > 4). Conclusion: Patients who have atrial fibrillation, NIHSS score >22 and GCS _< 8 on admission are at greater risk for severe disability at discharge or death.

1097 Circardian variation of Stroke onset in young Southern Indian rural population

Aleem, M 1, Ganasekaran, p1. IIC4P V GO VT. Medical College, Triehy, Ndia

Background: Studies have reported circardian variation in the onset of stroke, wlffch may carry important path physiological implication. However there is no detailed information about circardian variations among the young stroke patients.

Objective: To determine whether young stroke patients with specific clinical characteristics would exhibit different circardian patterns, to more systematically exanffne the rule of possible triggering or precipitating factors. Design setting: Tiffs prospective observational study was done at KAPV medical college A G M hospital Trichy from Jan 2002 for 2 years. All rural patients admitted with history of cerebrovascular disease were investigated following detailed history of onset of stroke. The data 's were analyzed for the circardian variation of young onset stroke. Results: Total nmnbers of stroke patients registered in two years were 674. Numbers o f young onset stroke below 40 years of age were 132 (19.58%). Male were 84 (163.63%) and female were 48 (36.36%). Mean age was 29 + 6.5 years. Patients with ischemic stroke were 92 (69.69%), hemorrhagic stroke were 12 (9.09*'/0), and Embolic stroke were 24 (118.18%).Time of onset of stroke fi'om 6 am to 12 noon were no ted in 32 (24.24%), from 12noon to 6 pm in40 (30.30%), f rom 6 p m to 12 night in 30 (22.72%) and from 12 night to 6 am in 30 (22.72%). Patients risk factors analysis showed smoking and tobacco usage in 60 (145.45%), alcohol usage in 30 (22.72%), rheumatic heart disease in 20 (15.15%) anticoagulant usage in 8 (6.06%) and no risk factor was found in 18 (13.63%). Conclusion: A m o n g 674 cases of stroke, young stroke in our rural populat ion is 19.58%. There is no sigtffficant morning peak in young stroke onset time in this study. Early morning stress does not cause. Stroke in young people free of underlying vascular disease.

1098 Clinical Epidemiological study of Stroke related Disability, risk anti prognostic factors

AITahan, A ~, AlWazna, T 2, Akeel, A 2, AlShammari , S 3, Zaidan, R 4, AlMuslimani, M e, Koja, ~/V 4. *King Saud University, Saudia Arabia.." ~Ministry of Health, Saudia Arabia; 3King Khalid University Hospital, Saudia Arabia," Q~lilitary Hospital, Saudia Arabia

Objective: To describe the outcome of stroke over one year, and the different features of stroke related disabilities in Saudi population. To assess the quality of life for patients and type of medical services available to them and the value of home visits. To assess the associated risk and prognostic factors, and finally to put forward recommenda- tions for future planrfing. Background: Stroke is the commonest cause of disability in affluent societies. As its incidence increases with age, its prevalence in Saudi Arabia, which is relatively low at the moment , is expected to rise in line with the increasing average life expectancy, and the incidence of diabetes mellitus and obesity. Tiffs will create a sizable load of stroke related disabilities on health services. Design/Methods: 75 patients, above the age of 14 yrs, with first clinical stroke were included in a prospective case-controlled, multicenter study between 01/10/2001 and 30/08/2002. Extensive demographic and clinical data & results of relevant investigations were obtained. Follow-up home visits were done on the 3 "a, 6 th and 1T h months after onset, and were finalized on 15/9/2003. Utilized instruments include Scandinavian Stroke Scale, Modified Barthel Index, Mirfi-mental State Examination. 122 controls matched for age, sex and residency were recruited to validate statistical analysis. Results: 70% of patients were above 50 yrs (16-95 yrs.). 66% were males and 34% females. 55*'/0 were hypertensive, 51"/o diabetics, 18"/o smokers, 10 % with cardiac disease and 15 % had preceding TIA's. The majority was not exercising. Strokes were ischemic in 80*'/0 and hemorrhagic in 20%. At 3 months , 3% were dead, 3% still in hospital and 94% discharged home. 56 patients were available for home visits. At 6 months more than 60% were fully independent, 78% mobile, 89% able to eat on their own and 80% fully continent. More than 50% of whom were working before stroke, returned to their original work, and another 25% returned as part-timers. More than 70*'/0 received physiotherapy while in hospital, and 40*'/0 after discharge. In the acute