1368 Book reviews

standing which they convey, and this is apity at a time when clinical immunologistsare struggling to emphasise the growingimportance of their subject in clinical prac-tice. A penultimate chapter by Roger Daw-kins on quality control in autoantibody test-ing is a reminder that this subject now alsoforms a specialised aspect of laboratorymedicine, with many pitfalls for the unwary.On the whole, this book is thoroughly rec-ommended for students, practising clin-icians, and laboratory workers as a well bal-anced up to date review of the subject.At £75, it is perhaps too expensive an

investment for an individual, but it is a mustfor a department's or institution's library.

RA THOMPSON

Skeletal Muscle. Handbook of MicroscopicAnatomy. Vol 2. Part 6. Ed H Schmalbruch.(Pp 440; 129 figs; DM 580.) Springer. 1985.ISBN 3-540-15608-9.

This impressive book covers the micro-anatomy of muscle of man and other spe-cies. The structure is described and illus-trated with high quality photomicrographs,electromicrographs, and illustrations. Thegeneral emphasis is on the possible linksbetween adaptations in structure and thosein metabolism or physiological functions.The latter part of the book is an author-itative account of development, regen-eration, and growth of muscle. It concludeswith a section on muscle fibres as membersof motor units and the influence of controlby the nervous system. Muscle pathologydoes not feature in this book, thoughclearly, the general mechanisms of celldegeneration and subsequent regenerationare well described. This book is extensivelyreferenced with some 2500 references. It is abook that seems to be reasonably priced andone which would be a valuable addition tothe library of anyone interested in muscleanatomy, physiology, or pathology.

RHT EDWARDS

Leukemia Therapy. Ed RP Gale. (Pp 277;£39-50.) Blackwells. 1986. ISBN0-86542-024-6.

With the aim of providing a review of leu-kaemia treatment by "balanced analysesrather than emphasising individual studies"

a cohort of Californian authors has assem-bled 250 pages of easily digestible text into11 chapters. Generally, the book succeeds; itis well referenced and as up to date as can beexpected. The views expressed are main-stream, and there is remarkably little evi-dence of hobby-horse riding.The contents include three general reviews

of chemotherapy, infections, and bloodproducts, and the remaining chapters aredevoted to the treatment of the childhoodlymphoblastic, adult lymphoblastic, myelo-blastic, chronic granulocytic, chronic lym-phocytic, hairy cell and plasma cell varietiesof leukaemia. There is also a section on thevarious myelodysplastic syndromes, whichthe authors still prefer to call "pre-leukaemia".Who should buy it? Certainly all the

libraries of specialist departments, post-graduate centres, and medical schools; butone suspects few individuals will be pre-pared to pay £40, which is a pity. If the pub-lishers had produced it for half the price,they may have more than doubled thepotential sales.

JS LILLEYMAN

Clarke's Isolation and Identification ofDrugs. 2nd ed. AC Moffat. (Pp 1248; £88.)The Pharmaceutical Press. 1986.

The first edition, published in 1969, was acompendium of analytical methods togetherwith a series of monographs on 1000 drugsand related compounds. A supplement, pub-lished in 1975, reviewed the chemical andphysical properties, metabolism, and tox-icity of a further 250 substances. This secondedition is a handsomely produced volume,which covers and updates most of the ma-terial in the first edition and adds a greatdeal of valuable information on new tech-niques and new drugs. There are 23 con-tributors to the analytical techniques section(300 pages); the editorial staff of the Phar-maceutical Society must have devoted a lotof effort to preparing the monographs onindividual drugs (750 pages) and the variousindexes (100 pages). They, and the consult-ing editors, have made a notable British con-tribution to the literature on analytical tox-icology. This book is a must for anypathologist who is faced with the problem ofidentifying, and perhaps quantitating, anunknown drug in a pharmaceutical product,a specimen from a living patient, or postmortem material.

SS BROWN

Notices

AssessorsThe members of the Editorial Board are indebted to the following for their help with the assessment of papers during the yearto 30 September 1986:

NC AllanJAL AmessT AndersonPP AnthonyJG AzzopardiNicola J BarnardDN BaronJS BeckDP BentleyCL BerryBarbara BillingAJ BintCC BirdLucille BitenskyTE BlecherSS BleehenWK BlenkinsoppAL BloomBorrieloA BoylstonJW BradfieldJM BridgesD Betty BrownellB BrozovicMilica BrozovicW BrumfittDW BullockPD ByersP ByfieldR CamplejohnV CattellMCK ChanI ChanarinJudith M ChessellsCharles ClarkeBarbara ClaytonDulcie V ColemanEC ColesLH CollierEH CooperB CorrinJ CrockerJulie CrowP CullRC CurranA Jane D'ArdenneP DandonaJF DavidsonAJS DaviesSally C DaviesDW DawsonDW DayAM DenhamJ DickinsonMF Dixon

I DoniachRAB DruryBI DuerdenJP DuguidDC DumondeS DundasMS DunnillIJ DurrantCSF EasmonRHT EdwardsHA EllisMargaret E ElmesAngela FairneyDr RJ FallonDr MA Ferguson-SmithRG FinchDG FleckCDM FletcherJ FletcherPT FluteCD ForbesARW ForrestAK FoulisH FoxM FrenchDL GardnerKC GatterCG GemmellH Gemmell MorganRH GeorgeAAM GibsonJ GoepelRB GoudieDI GrahamM GreavesPD GriffithsMR HaeneyP HallTJ HamblinRM HardistyDM HarrisPS HasletonS HeardR HeathKristin HenryEadie HeydermanD HillRL HimsworthJR HobbsCD HoldsworthMA HortonR HowdenMJ HudsonHelena E HughesJ Hume Adams

Rosalinde HurleyOAN HusainA JacobsVHT JamesJR JassDM JonesJA KanisPatricia KindI LauderACK LawrenceDA LevisonSM LewisGDO LoweSB LucasCA LudlamDWR MackenzieJS MalpasHB MarsdenDY MasonJ McClureDG McDonaldGA McDonaldGRD McDonaldA McQueenB McVerryISI MenziesLeslie MichaelsJ MilledgeCA MimsR MitchellVE MitchellDA MitchisonMJ MitchinsonP Morgan-CapnerP Morris JonesBC MorsonJA MurrayEGJ OlsenM Constance ParkinsonRN PeelMB PepysTJ PetersL PollerDJ PollockKA PorterAB PriceLH ReesPA RevellJ RhodesGL RidgwayMG RinslerRAR RisdonOS RoathBE RobertsSB Rosalki

D RosenB RoweD RusselPJ SandersonJG ScaddingJH ScarffePJ ScheuerD ScottA SegalM Buckley SharpN ShepherdNK ShintonMB SkirrowJP SloaneN SmithRC SpencerCJF SpryAG StansfeldA StephensH SternRM StewartJ StuartSoad TabaqchaliCED TaylorD Taylor-RobinsonRS TedderDR TrigerDR TyrrellJCE UnderwoodS VariendJS WainscoatN WaldF WalkerRosemary A WalkerAM WardCAJ WardropGF WattsDJ WeatherallJN WebbRO WellerJ WhicherWF WhimsterJA WhittakerED WilliamsAT WillisE Wilson JonesDA WinfieldCBS WoodDH WrightNA WrightPJ WyldAH WyllieAJ Zuckerman

1369

Volume 39: Author indexAbbreviations and symbols:- "(L)" refers to letters to the Editor;

*indicates first-named author.

ABBAS AMA, 582* (L)ABE S, 1193*ABEL P, 1165ADAMS FG, 114 (L)ADAMS JH, 769ADEMILUYI SA, 688*ADENIYI FAA, 1264*ADU D, 945AHMAD F, 343 (L)AHMAD WK, 925AINE R, 1042 (L)AKINYANJU OO, 688ALAVAIKKO M, 1042* (L)ALBANO JDM, 1151ALDER J, 542ALEGRE A, 1045 (L)ALESSANDRI C, 1003ALI M, 256ALI MH, 812* (L)ALLUM wH, 610*AL-MOUSSA M, 475,483*AL-TIMIMI AH, 29ALTMAN DG, 105AL-ZAHAWI MF, 927* (L)AMAGASAKI Y, 1193ANDERSON MC, 1140*ANDERSON MJ, 121, 1019ANDREW SM, 917*ANGUS B, 690 (L)ANSELL ID, 114 (L)ANTA JP, 1045 (L)ANTHONY PP, 761*, 1116ARMSTRONG JA, 353ARMSTRONG SS, 195ARRAGO Jp, 464 (L)ARROW SA, 212ASHWORTH MT, 1355*ATTENBURROW A, 698* (L)AUGER MJ, 134*AXON ATR, 524, 531AZIM T, 1317AZZI A, 118 (L)BAAK JPA, 406, 603, 1340*BAAR S, 722BABA M, 1254BABUDIERI S, 861BAILLIE M, 692 (L)BAKER K, 627BALFOUR AH, 1135BALSANO F, 1003BAMFORTH J, 215BANIK S, 446*BARCLAY FE, 1013BARCLAY GR, 458*BAREFORD D, 722*BARNETT AH, 722BARR A, 583 (L)BARRADAS MA, 344 (L)BARTL R, 237BASSO D, 75BATMAN PA, 757*

BATTERSBY RDE, 44, 810 (L)BAYSTON R, 654*BECK iS, 475, 483BELL J, 650BELLINGER CM, 1119BELLINGERI D, 961BENBOW EW, 345* (L)BENNETT CHN, 666*BENNETT JE, 1151BERRY Pi, 503BESSER GM, 955BETTA PG, 961BEVAN BR, 627*BEVAN PC, 260, 891BEVERLEY PCL, 399BHANA RH, 680BHATT B, 728BHATTACHARYYA MN, 1159 (L)BIANCHI FB, 897BIGNARDI L, 152BIRAN H, 794*BISHOP PW, 446BLACK RR, 1331BLACKSHAW AJ, 1*, 696 (L)BODDINGTON MM, 933BOHE M, 786*BOLLA M, 489BOLTON RP, 876*BOMFORD A, 449BONE G, 661BOOTH L, 215*BORELAND PC, 1360*BORGSTROM A, 786BORNE AEG KR VON DEM, 129BORRIELLO SP, 1013BOSQ J, 553BOUCHET Y, 489BOURGEOIS H, 1277 (L)BOWMAN RA, 212*BOXALL TA, 172BOYCE BF, 16BOYLE IT, 641BOYLSTON AW, 469, 1181BRADLEY J, 774BRADWELL AR, 813 (L)BRAGANZA IM, 464 (L)BRASSIL KE, 111*BRENES F, 459*BRETT MM, 1124*BRIDSON EY, 1259BROWN CB, 117 (L)BROWN CL, 933BROWN DFJ, 1006BROWN G, 564BROWN UR, 22*BROWN RA, 475*BROWN SE, 335BROWNELL Al, 121*, 253*BROZOVIC M, 253BRUNT PW, 195BULL K, 1130*

1370

BUNCE C, 564BUNCH C, 1301BUNYARATVEJ A, 1296BURKHARDT R, 237*BURLINA A, 75BURMAN JF, 1155BURNETT L, 808BURNETT RA, 114* (L)BURNIE JP, 1306BURNS J, 230* (L), 1066*BURT AD, 63*, 114* (L)BUTLER MG, 581 (L)BYRNE M, 256CAIRNS SR, 647*CALABUIG-CRESPO MC, 51CAMERON JS, 152CAMM AJ, 581 (L)CAMPION MJ, 1177CAMPLEJOHN RS, 542CANAVAN D, 1304*CANSFIELD JA, 232 (L)CAPSTICK IA, 112CAREY MP, 366CARLILE A, 284*, 423CARR T, 51, 736CASEMORE DP, 465* (L)CATOVSKY D, 1143CATTLE S, 1181CAYTON RM, 594CEVENINI R, 325*, 1313*CHAMBERS B, 717CHAMPOMIER F, 1039CHAN KW, 1105*CHAN PCY, 1021*CHAN R, 89*CHAN vTw, 230 (L)CHAPMAN CK, 813* (L)CHARNOCK M, 1335CHEETHAM P, 335*CHEN K-C, 260*CHESSELLS JM, 1236*CHIBA S, 84CHIN KS, 318CHOI CH, 1105CHRETIEN MF, 418*CHRIRAWONG P, 160CHRISTIANSEN FT, 573CLARK LA, 856*CLARKSON PK, 1177CLAYTON BE, 199CLAYTON P, 798*COATES Pi, 955*COHEN H, 1245COLE PJ, 176COLLINGHAM KE, 694* (L)COLLINS M, 1186COOKE RPD, 812* (L)COOKE T, 695* (L)COOKSON BD, 1364' (L)COOPER EH, 833COOPER IA, 987

Author index

COOVADIA YM, 680*CORDOVA C, 1003*CORNS CM, 293*CORSI oB, 118* (L)COSSART YE, 808COTTER KL, 876COWAN MD, 114 (L)COWAN RA, 641COX EL, 271COX H, 577CRAIG GT, 1108CRAWFORD DH, 1317CRAWFORD Ri, 583* (L)CRAXI A, 897CRESPI C, 897CRICK JA, 1229CRISTAL N, 635CROCKER j, 453, 564*, 923CROCKER PR, 172CRUICKSHANK JG, 1116CUBITT WD, 121CUMMING CG, 93CUMMINS D, 928* (L)CUNNINGHAM D, 267CURRY A, 1159 (L)DANDONA P, 344 (L), 638, 650

DANGERFIELD ViM, 44, 810 (L)DANIELS-LAKE W, 1236D'ARDENNE AJ, 138*, 145*, 581 (L)DARLEY CR, 1099DARLEY JH, 814 (L)DAVIDSON DF, 1158* (L)DAVIES 3D, 138DAVIS RE, 1040

DAWKINS RL, 573DEACON AG, 842*DEENMAMODE M, 717DELAMARRE 3FM, 1340

DEL FAVERO G, 75DEL NINNO E, 125DELSOL G, 553DESCHRYWER F, 464 (L)DESMET VJ, 1160 (L)DE VOS R, 1160 (L)DEWAR AE, 8DE WOLF-PEETERS C, 1160 (L)DHILLON AP, 1096

DICKSON ns, 371*DILLY SA, 440DI MARIO F, 75DING JC, 987DIXON MF, 524*, 531DJAZAERI B, 440DJURKOVICt-DJAKOVIC o, 204DODD SM, 913*DOHERTY VR, 189DOLAN j, 29*DONATI M, 1313DONIACH 1, 955DONNA A, 961*DORFMAN RF, 811* (L)DOUGLAS CWI, 871, 1108*DOYLE D, 769, 1217DRYBURGH Fi, 641DRYDEN MS, 1363* (L)DUBOIS MP, 418DUBOULAY cE, 215DUNNILL MS, 145, 590, 950DUPEYRON CM, 208*DYKKS PW, 813 (L)

EAGLES M, 908EASMON CSF, 856

EBLE JN, 1276* (L)EDEN OB, 998

EDMONDSON SJ, 581 (L)EDWARDS CW, 284, 423*, 594ELIAS-JONES j, 577*ELLIS 10, 497ENGLAND J, 393EPSTEIN O, 638ERBER W, 1301ESAKI Y, 1209ESIRI MM, 435, 615*, 1066, 1199EVAN GI, 577EVANS Di, 750EVANS DMD, 933*EVANS HJR, 757FABRIS C, 75FAGAN EA, 449FALINI B, 1229FALK S, 1161 (L)FALLON RJ, 693* (L), 811* (L)FARGION S, 125FEIZI T, 1165FELDMAN RG, 223*FELTHAM RKA, 798FERNIE JM, 697* (L), 1204*FERRO D, 1003FIELDING JWL, 610FIORELLI G, 125FLEMING KA, 58, 230 (L), 435FONSECA K, 220*, 1021FONSECA v, 638*FORD DW, 1140FOULKES Si, 535FRANCIS ND, 160,469*FREEMONT AJ, 731*FRIEDMAN N, 794FRISCH B, 237FUCHAROEN S, 1296FURNESS PN, 902*GALBRAITH SL, 1217GALL 3M, 458GALLOWAY A, 851*GARDNER BP, 851GARDNER MD, 641, 803GARRETT AJ, 318GATTER KC, 435, 547, 553, 590*, 950*, 1229GAYA H, 1013GERDES J, 590, 977*, 993*GERRIE LM, 195GHONEIM ATM, 1124GHOSH AA, 1335*GHOSH AK, 428*GIBSON JR, 215GILLON J, 458GIULIANO M, 861GODWIN PGR, 535GOH HS, 387*GOLDIN RD, 1181*GOLDSBOROUGH S, 920GONZALEZ R, 1045 (L)GOODFIELD Mi, 902GOODIER DW, 1046 (L)GOODWIN CS, 353*GOOSSENS D, 1039GOWENLOCK AH, 464 (L)GOZLAN-FIOR M, 489GRADWELL E, 917GRAHAM DI, 769

GRAY JJ, 1135GRAY SF, 1279* (L)GREEN HT, 851GUILLEMIN GA, 208GUNNEBERG A, 1158 (L)HALL PA, 622*HAMBLIN Ti, 713*HANN IM, 998HAQQANI MT, 1355HARPER CG, 769*HARRIS M, 428, 779HARRIS S, 459HARRISON B, 112HARRISON DJ, 167*HARTLEY RB, 152HASLETON PS, 29HAWKINS RA, 690 (L)HAWTIN P, 215HAYHOE FGJ, 891HEATLEY RV, 863HEIDENREICH W, 977HELLQUIST HB, 338*HEMSTED EH, 926* (L)HENDERSON AR, 803*, 828HENDERSON D, 1165HENDY-IBBS P, 577HENRY K, 1186HERMANS J, 603HIGGINS J, 654HIGHMAN Wi, 297*HINDER S, 1259HINKINS R, 1363 (L)HIROKAWA K, 1209HODGSON GS, 987HOLDSTOCK G, 215HOLLINSHEAD MS, 690* (L)HOPSU-HAVU VK, 1042 (L)HOPWOOD D, 1082HORNE CHW, 195*HORNY H-P, 596*HORTON LWL, 812 (L)HOULDER s, 60HOUWELINGEN JC VAN, 406HOWIE AJ, 1221HOWLETT TA, 955HUDSON EA, 933, 1347HUDSON 1, 1082*HUDSON P, 232 (L)HUGHES C, 582 (L)HUGHES DTD, 779HUGHES HE, 933HUNTER PR, 119* (L)ICHINOHASAMA R, 1209

IRELAND A, 215IRELAND JP, 1161* (L)IRONSIDE JW, 44*, 810* (L)IRONSIDE PNi, 987ISAACS D, 105*ISAACSON PG, 399ISON CA, 1119*IYORI S, 1193JACK AS, 16*, 267*JACOBI JM, 1353*JACOBS A, 1233JAGER K, 237JAGOE IR, 1347*JALALI MT, 464 (L)JAMAL O, 1096JAMES PD, 497*JARVINEN M, 1042 (L)

1371

1372JARVIS LR, 1096, 1276 (L)JASANI B, 230 (L)JASS JR, 387, 393*, 585*, 1088JEEPS CM, 199*JEFFS JB, 29JELENSKI G, 256JENKINS D, 1177*JENKINS 3M, 627JENNINGS PE, 722JOHNS EA, 833*JOHNSTON D, 524JONASSON JA, 230 (L)JONES EW, 742JONES N, 1165JONES RR, 742*JONES TJ, 1221*JOYNSON DHM, 666JUNEJA SK, 987*JUNGLEE D, 638KAISERLING E, 596KARHUNEN PJ, 183*KARK AE, 647KARRAN SJ, 1245KATER L, 406KATO E, 1193KATRAK A, 638KAWAHARA Y, 1209KAY J, 1323KAY LA, 234* (L), 684*KAYE GC, 581* (L)KEEN AP, 118* (L)KELLAND D, 900KENDALL CH, 231* (L), 908*KERR EJC, 692 (L)KERTTULA Y. 1250*KETTNER G, 237KHALAF MR, 891*KIMURA H, 981KING A, 661*KING G, 690 (L)KING RFJG, 524KIRKPATRICK P, 138KITE P, 695 (L)KJAELDGAARD A, 1241*KJAELDGAARD M, 1241KNOWLES S, 1049*KOGAWA K, 84KONISHI K, 1193KORNPROBST M, 1039*KRAJEWSKI AS, 8, 275, 1043 (L)KRAMBOVITIS E, 779*KRISHNAN KR, 851KRISTINSSON KG, 117* (L)KUMAR s, 51*, 736*KURTSEFER L, 977LAFFAN MA, 1143*LAMB D, 697 (L), 1204LAMBERT JR, 112LAMPERT IA, 750LANGDALE P, 233* (L)LANGLEY FA, 1340LAOHAPAND T, 160LA PLACA M, 325, 1313LAUSLAHTI K, 68LAW SM, 223LEADER M, 1186*LEE FD, 16, 267, 677LEFRERE JJ, 1277* (L)LELIE J VAN DER, 129*LELLE RJ, 977

LELUAN GJ, 208LEMOINE NR, 271*, 622LENNERT K, 596LEUNG KBP, 279LEVER JV, 698* (L)LEVEY JM, 463* (L)LEVINE AM, 1042 (L)LEVISON DA, 1, 172*, 696* (L), 1161 (L)LEWIS SM, 717LEYLAND Mi, 453LIDDLE CN, 267LILLEYMAN JS, 998*LINDEMAN J, 603LINDEN HC VAN DER, 603*LINDSTROM C, 786LISE M, 75LITTLEWOOD JM, 1124LLOYD B, 199LLOYD HM, 1353LLOYD RS, 215LOCKE DE, 234 (L), 684LOSOWSKY MS, 876, 1124LOUGHLIN JF, 828*LOWE D, 927 (L)LOWE J, 697* (L), 774*LOWE SB, 808LOWSON S, 253LUCAS S, 696* (L)LUKES RJ, 1042 (L)LUOSTO R, 1074MACARTNEY JC, 542*MACBRIDE H, 215MCCANCE DJ, 927* (L), 1177MCCANN VJ, 573MCCARTHY P, 1245MCCLURE J, 690 (L), 920*MCCLUSKEY E, 908MACDONALD F, 610MCDONALD GA, 677MACDONALD MK, 167MACDONALD SM, 1199*MCDONNELL MK, 695 (L)MACDOUGALL J, 220MCGEE J O'D, 230 (L), 615, 1066MCGONIGLE RJS, 945MCGOVERN J, 923*MACHIN si, 701, 1245MCILLMURRAY MB, 1317MCINTYRE M, 1224MCINTYRE N, 638MACKENZIE EFD, 933MACKIE Ii, 701, 1245*MACKIE MJ, 134, 1019MACKIE RM, 189MACKINNON s, 677*MACLAREN DM, 376MACLENNAN ICM, 833MACLENNAN KA, 902MCNICOL AM, 677MACSWEEN RNM, 63MCSWIGGAN DA, 121MACVARISH I, 583 (L)MCWHINNEE D, 145MAHL G, 237MAINZER K, 596MALASIT P, 160MALCOLM AJ, 339MALNICK H, 342 (L)MARCHESINI A, 961MARCHIORO L, 75

Author indexMARPLES RR, 371MARSDEN HB, 51, 508*, 736MARSHALL Bi, 353MARSHALL T, 933MARTLEW VJ, 1147*MASON DY, 547, 553, 590, 950, 1229MASON GC, 29MATTHEWS J, 695 (L)MATTHEWS JG, 260MATTHEWS N, 1130MATTHEWS RC, 1306*MAWHINNEY WHB, 339MAY A, 1233MAYSTON V, 271MEDLEY G, 112MEIGH RE, 1019MELLARS B, 232 (L)MENON KK, 851MERMET MA, 489MEYER CJLM, 603MEYER PR, 1042 (L)MICHAEL J, 366, 945MIKHAILIDIS DP, 344* (L), 638MILBORROW HM, 808*MILLAR MR, 233 (L), 695* (L)MILLARD LG, 902MILLER AL, 293MILLER K, 393MITCHELL Ci, 798MITCHELL DN, 176MITCHELL R, 583 (L)MITCHELL RG, 118 (L)MONIZ CF, 838*MOODLEY N, 680MOORE M, 428MORALEDA 3M, 1045* (L)MORDI VPN, 688MORGAN-CAPNER P, 232* (L), 1317*MORONI A, 1313MORRIS JA, 691* (L), 1317MORRIS PJ, 145MORRIS RW, 1151MORRIS-JONES PH, 736MOTOYA H, 84MOURIQUAND J, 489*MOWAT NAG, 195MULLER H, 1161* (L)MULLER K, 596MUMTAZ G, 232 (L)MUNRO CS, 176*MUNRO R, 89MUSCAT I, 1116*MVANTEMBE O, 1158 (L)MYSKOW MW, 1043* (L)NACCARATO R, 75NAJEAN Y, 464* (L)NAKAMURA S, 1254NAKAMURA T, 981*NAKANO G, 981NAKAO T, 84NAMAVAR F, 376NAR P, 453NARDI F, 861NASH JRG, 134NAYLOR 3, 908NEILD GH, 152*NELSON DB, 318NEUMANN L, 794NEWMAN GR, 230* (L)NEWTON WA, Jnr, 508

Author index

NICOL DJ, 1040NICOLAIDES KH, 838NIGHTINGALE BN, 808NILWARANGKUR S, 160NIMMANNIT S, 160NOBBS GL, 116* (L)NORDBACK 1, 68*NORTON Ai, 399*NORTON R, 929* (L)NOZAKI H, 1254NUMAZAKI K, 84*NUTTALL PA, 332*OATES K, 691 (L)O'BRIEN TEB, 446O'CONNOR Hi, 524, 531*O'CONNOR NTJ, 1229*, 1301OGATA M, 1254OGG cs, 152O'HEA AM, 1301*OHLSSON K, 786OKISHIGE K, 1209OKONOFUA F, 650*OKUAKI A, 1254OLBERMANN M, 596ORIEL JD, 232 (L)ORMEROD F, 342 (L)ORMEROD LP, 446OSCIER DG, 713OSMAN S, 717PACKE GE, 594*PALLETT CD, 339*PANAIOTOPOULOS N, 125PANICHI G, 861PANUCCI A, 75*PARICHATIKANOND P, 160*PARKIN JD, 987PARKIN JM, 469PARSONS MA, 44PARWARESCH MR, 596PATEL J, 1186PAYNE A, 928 (L)PAZ MOA, 459PEACH SL, 1013*PEAKE Mi, 1025, 1031PEARCE FL, 279PEARSE RG, 383PEARSON AD, 215PEARSON EC, 99*, 569*PEASE AA, 871*PECKHAM Cs, 318*PENNINGTON GW, 627PEREZ-ROMANO B, 227PERINPANAYAGAM RM, 342 (L)PETERS AM, 717*PETERS R, 1233*PETERS TJ, 647PETERS WM, 306*PETROVIC LM, 459PETTY AC, 1155*PHILLIPS I, 661PHUA TJ, 1006PICCOLI A, 75PICKARTZ H, 977PINCOTT JR, 1236PINKARD KJ, 112*PIPERNO A, 125*PIPPARD M1, 881PISI E, 897PITT TL, 220POLAK A, 1151

POLANSKA Al, 1278* (L)POLLOCK DJ, 1099POMMIER Y, 464 (L)POOLEY FD, 313*POON GP, 1105PORTMANN B, 449POSTON RN, 514*POULTER LW, 176POUPLARD-BARTHELAIX A, 418POWELL G, 542PRAS M, 794PRASARTKAEW S, 1296*PREECE PM, 318PUBBEN ANB, 376PULFORD KAF, 547PYRAH RD, 343 (L)RALFKIAER E, 547*, 553*RALSTON SH, 641*RAMSAY AD, 399RANDALL KJ, 172RANSON DL, 313RATCLIFFE JG, 116 (L)RATHBONE BJ, 863, 1279 (L)REAVY Hi, 717REBEL A, 418REDFERN DRM, 1066REES LH, 955REID H, 345 (L)REID WA, 1217*, 1323*REVELL PA, 271RHODES J, 1130RHODES JM, 1331*RICHARDS R, 256RICHARDS SM, 29, 998RICHMOND HG, 1217RIDGWAY GL, 232* (L)RILEY TV, 212RINNE A, 1042 (L)RIORDAN T, 1159* (L), 1276* (L)ROBERTS BE, 343 (L), 728ROBERTS C, 116 (L), 346 (L)ROBINSON F, 1304RODE J, 1096RODECK CH, 838ROSA R DI, 861ROSE PE, 812 (L)ROSS PW, 93ROTHBURN MM, 116* (L)ROTHMAN SW, 672*ROUGER PH, 1039ROXBY CM, 927 (L)RUDGE CJ, 152RUIZ-ARGUELLES A, 227*

RUMPIANESI F, 325, 1313RUSSELL Ai, 440RUSSELL GA, 503*RUTLEY C, 731RYAN iF, 271, 1099*SAATI TA, 553SAEED A, 232 (L)SAGE JC, 489

SAKAGUCHI H, 1193SALIMONU LS, 231* (L)SALIOLA M, 1003SALISBURY JR, 223SALMON CH, 1039SALTER DM, 8*, 275*SAMBRI V, 325, 1313SANDERSON IR, 279*SANDERSON Y, 695 (L)

1373SANGSTER G, 453*SAN MIGUEL IF, 1045 (L)SARIOLA H, 1074*SAVAGE A, 1331SAVVAS M, 627SAWHNEY D, 1259*SCHEUER Pi, 459SCHWARTING R, 977,93SCIOT R, 1160* (L)SCOTT CS, 343 (L), 728SCOTT SD, 1245SEYWRIGHT MM, 189*SHAINKIN-KESTENBAUM R, 635*, 794SHARMA GK, 969*SHAW AC, 343 (L)SHAW KM, 1151SHEARER M, 1245SHEPHARD MDS, 1025*, 1031*SHIGETA S, 1254*SHIOTA T, 1269*SHORTLAND-WEBB WR, 366SHRESTHA TL, 927 (L)SIBALIC D, 204*SIDHU Ys, 514SIENKOWSKI IK, 440*SILCOX A, 199SIMARD C, 418SIMMONS P, 927 (L)SIMPSON EM, 1046 (L)SINCLAIR TS, 195SINGCHOOVONG L, 160SINGER A, 1177SINGH v, 680SKAARLAND E, 36*SKILBECK N, 564SKINNER JM, 1096, 1276 (L)SLAVIN G, 581 (L)SLOOTWEG Pi, 406SMALLMAN LA, 366*SMART LE, 328*SMILLIE D, 114 (L)SMITH BK, 1040*SMITH DB, 29SMITH GLF, 93*SMITH JF, 1353SMITH SH, 399SMYTH EG, 343* (L)SNEATH PHA, 798SNELL JJS, 1006*SOUKOP M, 267SPAULL J, 742SPELLER DCE, 1046 (L)SPENCER RC, 117 (L), 463* (L), 871, 925*SPRIGGS Al, 1335SPRY C, 742STAFF WG, 691 (L)STARK AN, 343* (L), 728*STAUCH G, 977STEIN H, 590, 977, 993, 1229STEIN PE, 1046* (L)STEPHENSON JR, 1271*STEVENS A, 902STEVENS RF, 998STOCKDILL G, 1224STOKER M, 1360STOKES Hi, 610STONE JW, 945STONE MG, 542STONE PCW, 722STOTT A, 346* (L)

1374STRATTON M, 750*STUART j, 722STURM AW, 1157*STUTTE HJ, 1161 (L)SUGIHARA K, 1088*SUND M, 237SWAINE D, 1259SWASH M, 271SYNNOTT M, 694 (L)TABAQCHALI S, 1271, 1306TADDEI MT, 125TALAVERA JG, 1143TALBOT IC, 969TALERMAN A, 1340TANAKA M, 1209*TANAKA Y, 1209TARBIT IF, 817*TAUBE DH, 152TAY SK, 1177TAYLOR NF, 627TAYLOR S, 230 (L)TEBBUTT GM, 78*TELESINGHE PU, 761TESDALE A, 690 (L)MESTORE GP, 861*THEAKER JM, 58*, 435*THOMAS GDH, 464* (L)THOMAS JA, 1317THOMAS RUS, 987THOMPSON JF, 145THOMSON D, 167THOMSON JPS, 927 (L)THORPE SJ, 1165*TIMPERLEY WR, 44, 810 (L)TOMLINSON P, 89TOMPKINS DS, 535*TSELENI S, 697* (L)

TSIANOS EB, 464* (L)TUCKERMAN JF, 828TURKINGTON P, 1304TURNER R, 833TZANNATOS C, 838UKO G, 573*UMETSU M, 84UNDERWOOD JCE, 44, 810 (L)VALLER MJ, 1323VALMAN HB, 105VANICHAKARN S, 160VAN MUIJEN GNP, 950VARIEND S, 383*VEL WAC, 376*VERWEIJ-VAN VUGHT AMJJ, 376VILJANEN T, 1074VILLEMAIN D, 489VIOLI F, 1003VOGEL W, 449*WAGHORN DJ, 1363* (L)WAINSCOAT IS, 1229WALKER J, 1119WALKER-SMITH JA, 279WALMSLEY RN, 1031WALSHE K, 1245WANTZIN GL, 547WARE I, 814* (L)WARREN DE, 318WASHBROOK NP, 1347WASI P, 1296WATSON JV, 577WATSON KC, 692* (L)WAITS GF, 1151*WATTS M, 928 (L)WEBER j, 469WEBER TH, 1250WEIGHTMAN NC, 1046* (L)

Author indexWEINBREN Mi, 342* (L)WELCH AR, 1013WELLS CA, 138WELLS M, 22WEST AP, 535WEST NC, 1019*WHALE K, 114* (L), 811* (L)WHEAT PF, 463 (L)WHITE JM, 256*WHITEHEAD F, 1276* (L)WHITEHEAD R, 696* (L), 1276 (L)WICKRAMASINGHE SN, 881*WILCOCK A, 695 (L)WILDE PCM DE, 406*WILKINS EGL, 116 (L)WILLIAMS AH, 1161 (L)WILLIAMS DG, 152WILLIAMS ED, 230 (L)WILLIAMS R, 449WILIAMS RA, 1096*WILLIAMS WJ, 900*WINDSOR JJ, 851WINIKOFF Y, 635WINSTANLEY TG, 463 (L)WISSE-BREKELMANS ECM, 1340WOLF MM, 987WOMACK C, 114* (L)WONG SY, 690* (L)WOOD RPM, 145WREGHITT TG, 1135*WRIGHT AF, 1281*WYATT Ji, 531, 863*, 1279 (L)YAP PL, 458YARDUMIAN DA, 701*YATES P, 1224*YOUNG BJ, 713YOUNG JA, 36, 945*ZAULI D, 897*

Volume 39: Subject indexAbbreviations:-"(L)" refers to letters to the Editor.

Aborted fetuses. See Fetuses, abortedAbscess of breast, non-puerperal, pathogenic role of Mobiluncus spp

in (L), 342ACTH and somatostatin like immunoreactivity in small cell car-cinoma of lung, 418

Adenocarcinoma, prostatic, evolving into carcinoid, 2 cases of, selec-tive effect of hormonal treatment?, 750

, scar, of lung, light and electron microscopic study, 423Adenoid cystic carcinoma, laminin and fibronectin in, 138Adenoma, carcinoma, and hyperplastic polyps, colonic, glycoprotein

abnormalities shown by lectin peroxidase histochemistry, 1331Adenoma-carcinoma sequence and DNA content in colorectum, 387Adenomatosis of small intestine, case of, 981Adenomatous polyps of colon, ploidy studies in (L), 695, 696, 1276Adrenal and parathyroid autoantibodies, coexisting, rarity of (L),813

Adrenaline stimulation in vitro of plasminogen activator release fromvein walls, 1241

Adrenocorticotrophic hormone. See ACTHAerobic bacilli, Gram-negative, identification of, kit systems for

(Welsh Standing Specialist Advisory Working Group in Micro-biology report), 666

Age and smoking, effects on imtima of muscular pulmonary arteries,1204

Aging and senile dementia of Alzheimer type, effects on dihydro-pteridine reductase activity in dried blood spots, 199

process, histological changes in sublabial salivary glands due to,morphometric study of, 406

AIDS, accessory cells as primary target ofHIV infection in (L), 1161and anti-HTLV-III positive laboratory reagents (L), 346Kaposi's sarcoma in, 469

in patients with and without, histogenesis of, 742Airways disease, obstructive, chronic, f lactamase producing 'non-

pathogens' in, detection and importance of (L), 343Albumin, urinary, determination at low concentrations, new radio-immunoassay kit for, assessment and comparison with radialimmunodiffusion, 1151

Alcohol, hypertension caused by, interactive roles of monovalent anddivalent cations in pathogenesis, 1264

Alcoholic liver disease, hepatic vein lesions in, retrospective biopsyand necropsy study, 63

, IgA deposition in, 1181Alkaline phosphatase isoenzyme activity in serum, determination of,

quantitative method with guanidine hydrochloride, 1025, 1031Alpha-l-antitrypsin. See a1-AntitrypsinAlzheimer type senile dementia and aging, effects on dihydropteridine

reductase activity in dried blood spots, 199Alzheimer's disease, monoclonal antibody (SMP) binding to con-

gophilic elements in human brain in, 1199Amyloid A, serum concentration, variations in cancer, correlation

with disease activity, stage, primary site, and prognosis, 794--, concentrations during course of acute ischaemic

heart disease, 635, atrial, immunoreactive atrial natriuretic peptide in,

identification of (L), 581Anaemia, dyserythropoietic, type I, congenital, erythroblast function

in 2 patients with, evidence of impaired DNA, RNA, and proteinsynthesis and other abnormalities, 881

, haemolytic, immune, and nomifensine treatment, 6 cases in NWEngland (1984-85), 1147

iron deficiency, erythroblastopenia in, human parvovirus asso-ciated with (L), 1277

Anaemias, haemolytic, clinical use of .. In labelling of red cells in(L), 464

Anaerobic cocci, Gram positive, survival on swabs and isolation frommouth and vagina, 93

coccoid rods, antibody response to, in Crohn's disease, 1130Angioimmunoblastic lymphadenopathy, monoclonal T cell prolif-

eration in, evidence for, 1229Angiotensin converting enzyme, serum concentrations in pneu-

monias, 1250Antibiotics, coryneforms group JK resistant to, biochemical and cul-

tural characteristics of, 654, prescribing preferences of general practitioners in Leeds area,

influence of laboratory sensitivity reporting policy (L), 233Antibodies, monoclonal. See Monoclonal antibodies-to Pseudomonas aeruginosa cell surface antigens in sera in cystic

fibrosis, development of ELISA for detection of, 1124Antibody, IgG and IgA, responses in serum associated with Cam-

pylobacter pyloridis in patients undergoing upper gastrointestinalendoscopy, 215-9monoclonal. See Monoclonal antibodyresponse to anaerobic coccoid rods in Crohn's disease, 1130

-to hepatitis B surface antigen, donor screening for (L), 583Anticomplement immunofluorescence antibody titration, importance

for diagnosis of varicella-zoster virus infection in Bell's palsy, 1254Antigen, Ca, and urothelial antibacterial defences (L), 691

, carcinoembryonic, expression in normal, chronically inflamed,and malignant pancreatic tissue, immunohistochemical demonstra-tion of, 610

, in serum, diagnostic accuracy in pancreatic cancer, com-parison with tissue polypeptide antigen, 75

, chlamydia, detection of, ELISA for, false positive results with(L), 1276

,Chiamydia trachomatis, detection by enzyme immunoassay,immunofluorescence, and cell culture (L), 232

, epithelial membrane, and cytokeratin, expression by meningio-mas, immunohistological study, 435

-, fibronectin, and laminin, antisera to, study of child-hood renal tumours using, 51

Ki- I positive cells, Reed Sternberg associated, in normal lym-phoid tissue, high proliferative activity of, 993

, leucocyte, common, cytokeratin, and other markers in immu-nohistochemical diagnosis of tumours on routine surgical sections,514-, streptococcal, group B, detection in necropsy specimens using

monoclonal antibody and immunoperoxidase staining, 223,tissue polypeptide, diagnostic accuracy in pancreatic cancer,

comparison with serum CEA, 75Antigens, blood group, expression in urinary tract tumours,

fluorescence study using cryostat sections of fresh frozen tissues,1165

, HLA, and idiopathic haemochromatosis in Italy, with A3 Bw35HLA haplotype as marker for idiopathic haemochromatosis genein NE regions, 125

Antimicrobial susceptibility testing and identification in 24 hours forrapid diagnosis of Gram negative urinary infections, 208

of Haemophilus influenzae, trial for UK nationalexternal quality assessment scheme for microbiology, 1006

- of Pseudomonas maltophilia (L), 463Antioxidative enzyme activities in erythrocytes, comparison between

2 types of haemoglobin H disease, 1296Antisera to fibronectin, laminin, and epithelial membrane antigen,

study of childhood renal tumours using, 51a,-Antitrypsin and liver, results of routine immunohistological

screen, 58Anus, condyloma acuminata of, human papilloma virus in (L), 927Aortic dissections, histological pattern and changes in extracellular

1375

1376matrix in, 1074

API-IOS strips for biotyping Haemophilus influenzae, comparisonwith tube tests (L), 692

Aplastic crisis in patient with HEMPAS, parvovirus infection associ-ated with, 1019

Arabinitol estimations in serum for diagnosis of invasive candidosis,842

Arterial blood gas analysis, effect of sodium citrate anticoagulant in

vitro on results of (L), 1046Arteritis, isolated, of epididymis (L), 114Arthritis, rheumatoid, complicated by malignant histiocytosis, 4

cases of, 16Asbestos fibre dust counts in lung tissue obtained by analytical elec-

tron and light microscopy, comparison of results, 313Aspergillus infection, cerebral and orbital, due to invasive asper-

gillosis of ethmoid sinus, case of, 774Aspiration biopsy cytology, fine needle, of lung, experience with cell

block technique in (L), 114of thyroid, confusion of subsequent histol-

ogy due to (L), 697, 698Atrial amyloid, immunoreactive atrial natriuretic peptide in,

identification of (L), 581Atrioventricular node, mesothelioma of, primary, causing sudden

death, case of (L), 926Auer rods in acute myeloblastic leukaemia, crystal structure of, 569Authorship, International Committee of Medical Journal Editors

guidelines, 110Autoimmune sialadenitis, malignant epithelial tumours associated

with, 2 British cases of, 497Autoimmunity in chronic liver disease caused by hepatitis delta virus,897

lymphocytic leukaemia, 713

Bacilli, aerobic, Gram-negative, identification of, kit systems for(Welsh Standing Specialist Advisory Working Group in Micro-biology report), 666-, Gram negative, low cost identification in clinical laboratories,

construction of database for, 798Bactec radiometric system for blood cultures, comparison with Oxoid

gas capture system, 661Bacteraemia, detection of, manual or radiometric method for (L), 582

,early detection of, high speed centrifugation in, 1157suspected, C-reactive protein concentration in (L), 1363

Bacteria, nitrate reduction by, commercial strip test for (L), 118-on blood films (L), 928Bacterial meningitis, normocellular, 4 cases of (L), 694Bacteroides sp, Escherichia coli, and polymorphonuclear leucocytes,

interactions between, role in pathogenesis of mixed infection, 376Beckman airfuge centrifugation in rapid method for concentration of

hepatitis B virus particles, 808Bell's palsy, varicella-zoster virus infection in, diagnosis of,

importance of anticomplement immunofluorescence antibodytitration for, 1254

Beryllium disease, chronic, diagnosis by laser ion mass analysis, 900

Beta-propiolactone, effect on haemoglobin electrophoresis (L), 814Bezoar composed of coconut matting identified by combined ana-

lytical approach, 172Biliary cirrhosis, primary, serum immunoreactive trypsin and pan-

creactic lipase in, 638Biochemistry, clinical. See Clinical biochemistryBiotinylated probes, in situ hybridisation with, human and viral gene

detection in paraffin embedded tissue by, and viral localisation inherpes encephalitis, 1066

Blood, arterial, gas analysis, effect of sodium citrate anticoagulant invitro on results of (L), 1046

-culture, conventional, lysis filtration as adjunct to, evaluation of,

89systems, comparison of Bactec radiometric and Oxoid gas

capture systems, 661

Subject indexcultures, growth of micro-organisms in, detection of, novel

method for, 1259-donor screening for anti-HBs (L), 583

sera, large scale screening with latex agglutination methodfor IgA deficiency, 458

films, bacteria on (L), 928-group antigen expression in urinary tract tumours, fluorescence

study using cryostat sections of fresh frozen tissues, 1165platelet. See Platelet

-spots, dried, dihydropteridine reductase activity in, effects ofaging and senile dementia of Alzheimer type, 199

Bone marrow involvement with T cell lymphoma, 3 cases initiallypresenting as abnormal myelopoiesis, 134-necrosis and interferon treatment (L), 1045

trephines, benign and malignant (B cell) focal lymphoidaggregates demonstrated by immunogold-silver technique in, 453

Book reviews:Abraham EC: Glycosylated Hemoglobins: Methods ofAnalysis and

Clinical Applications (Clinical and Biochemical Analysis Series,Vol 19), 1985, 1048

Advances in Cancer Research, Vol 45, 1985, 699Advances in Clinical Chemistry, Vol 24, 1985, 1047Anderson JR: Atlas ofSkeletal Muscle Pathology (Current Histo-

pathology Series, Vol 9), 1985, 350Andersson LC, Gahmberg CG, Ekblom P, eds: Gene Expression

during Normal and Malignant Differentiation, 1985, 699Ansell ID: Atlas of Male Reproductive Pathology (Current Histo-

pathology Series, Vol 10), 1985, 235Baldwin RW, Byers VS, eds: Monoclonal Antibodies for Cancer

Detection, 1985, 930Bancroft JD, Chalk BT: Self-Assessment in Histological Tech-

niques, 1985, 350Bates M, ed: Bronchial Carcinoma: An Integrated Approach to

Diagnosis and Management, 1984, 931Berlin A, etal, eds: Monitoring Human Exposure to Carcinogenic

and Mutagenic Agents (IARC Scientific Publications, No 59),1985, 347

Berman MC, Gevers W, Opie LH, eds: Membranes and Muscle,1985, 468

Blaustein A: Interpretation ofEndometrial Biopsies, 2nd ed (BiopsyInterpretation Series), 1985, 1163

Brain's Diseases of the Nervous System, 9th ed, 1985, 814Brooks GF, Donegan EA: Gonococcal Infection (Current Topics in

Infection Series), 1985, 351Bryant NJ: Laboratory Immunology and Serology, 2nd ed, 1986,

1366Bullock GR, Petrusz P, eds: Techniques in Immunocytochemistry,

Vol 3, 1985, 466Clarke's Isolation and Identification of Drugs, 2nd ed (ed AC

Moffat), 1986, 1367Collins CH, Grange JM, eds: Isolation and Identification ofMicro-

Organisms of Medical and Veterinary Importance (Society forApplied Bacteriology Technical Series No 21), 1985, 347

, ,,Yates MD: Organisation and Practice in TuberculosisBacteriology, 1985, 1163

Culling CFA, Allison RT, Barr WT: Cellular Pathology Technique,4th ed, 1985, 467

Curran RC: Colour Atlas of Histopathology, 3rd ed, 1985, 347Current Topics in Veterinary Medicine and Animal Science, Vol 32,

Brucella Melitensis, 1985, 467Dalton HP, Nottebart HC: Interpretive Medical Microbiology,

1986, 1162Davis RL, Robertson DM: Textbook ofNeuropathology, 1985,699Dubowitz V: Muscle Biopsy, 2nd ed, 1985, 698Eastham RD, ed: Biochemical Values in Clinical Medicine, 7th ed,

1985, 932Edwards R: Immunoassay: An Introduction, 1985, 348Ellis WA, Little TW: The Present State of Peptospirosis Diagnosis

and Control (Current Topics in Veterinary Medicine and AnimalScience), 1986, 1047

Subject indexFarr AD: Science Writing for Beginners, 1985, 348Feldman PS, Covell JL: Fine Needle Aspiration Cytology and its

Clinical Applications: Breast and Lung, 1985, 235Filkins K, Russo JF, eds: Human Prenatal Diagnosis (Clinical and

Biochemical Analysis, Vol 18), 1985, 348Furth R van, ed: Mononuclear Phagocytes: Characteristics,

Physiology and Function, 1985, 815Gale RP, ed: Leukemia Therapy, 1986, 1367Glyn E, Evans V, Gentles JC: Essentials of Medical Mycology,

1985, 930Gray CH, Howorth PJN, Rinsler MG: Clinical Chemical Pathol-

ogy, 10th ed, 1985, 930Haagensen CD: Disease of the Breast, 3rd ed, 1986, 1047Hall WD, Saunder E, Shulman NB: Hypertension in Blacks: Epi-

demiology, Pathophysiology and Treatment, 1985, 235Hames BD, Higgins SJ, eds: Nucleic Acid Hybridisation, 1985, 468Holton JB: An Introduction to Inherited Metabolic Diseases, 1985,

350Kemp I, Boyle P, eds: Atlas of Cancer in Scotland 1975-1980:

Incidence and Epidemiological Perspective (IARC Scientific Pub-lications, No 72), 1985, 1279

Kimura Y, Kotami S, Shiokawa Y, eds: Recent Advances in Strep-tococci and Streptococcal Diseases, 1985, 349

Kirsch RE, et al, eds: Liver Update 2/1985: Proceedings ofan Inter-national Symposium on Recent Advances in Liver Physiology andDisease, 1985, 467

Kline TS: Guides to Clinical Aspiration Biopsy: Prostate, 1985, 929Koss LG, Woyke S, Olszewski W: Aspiration Biopsy: Cytologic

Interpretation and Histological Bases, 1985, 348Leistenschneider W, Nagel R: Praxis der Prostatazytologie: Tech-

nik und Diagnostik, 1984, 815Lenoir GM, O'Conor GT, Olweny CLM, eds: Burkitt's Lym-phoma: A Human Cancer Model (IARC Scientific Publications,No 60), 1985, 349

Lewis SM, ed: Myelofibrosis: Pathophysiology and Clinical Man-agement (Haematology, Vol 4), 1985, 347

Likhachev A, Anisimov V, Montesano R, eds: Age-Related Fac-tors In Carcinogenesis (IARC Scientific Publications, No 58),1986, 930

Lucas RB, Eveson JW: Atlas of Oral Pathology (Current Histo-pathology, Vol 8), 1985, 466

McDonagh J, ed: Plasma Fibronectin: Structure and Function(Haematology Series, Vol 5), 1985, 930

McLay AIC, Toner PG: Subcellular Taxonomy: An UltrastructuralClassification System, 1985, 929

Major Problems in Pathology, Vol 16, Surgical Pathology of theLymph Nodes and Related Organs, 1985, 1047

, Vol 17, Surgical Pathology of Bone Marrow:Core Biopsy Diagnosis, 1985, 816

Mardell RJ, Gamlen TR: Thyroid Function Tests in Clinical Prac-tice, 1985, 584

Ming S-C: Tumours ofthe Esophagus and Stomach (Atlas ofTumorPathology, 2nd series), 1985, 351

Morgan AJ: X-Ray Microanalysis in Electron Microscopy for Bio-logists (Microscopy Handbooks, 05), 1985, 467

Muir's Textbook of Pathology, 12th ed (JR Anderson, ed), 1985,466

New Perspectives in Clinical Microbiology, 11, Clinical Problems inSexually Transmitted Diseases, 1985, 584

Nieburgs HE, Holzner JH, Valli VE, eds: Tumor Markers in Can-cer Control, 1985, 583

Noe DA: The Logic of Laboratory Medicine: Principles for Use ofthe Clinical Laboratory, 1985, 466

Pal SB, ed: Handbook ofLaboratory Health and Safety Measures,1985, 235

Parkin DM, Wagner G, Muir CS, eds: The Role of the Registry inCancer Control (IARC Scientific Publications, No 66), 1986,1280

Pathology Annual 1986, Part 1, 1986, 929Progress in Clinical and Biological Research, Vol 189, Bacterial

1377Endotoxins: Structure, Biomedical Significance, and Detectionwith the Limulus Amebocyte Lysate Test, 1985, 352

-,Vol 195, Cellular and MolecularAspects of Aging: The Red Cell as a Model, 1985, 465- , Vol 196, Advances in Microscopy,

1985, 931Quaglino D, Hayhoe FGJ, eds: The Cytobiology ofLeukaemias and

Lymphomas (Sereno Symposia Publications, Vol 20), 1985, 698Reichard S, Kojima M, eds: Macrophage Biology (Progress in

Leukocyte Biology, Vol 4), 1986, 1366Reisfeld RA, Sell S, eds: Monoclonal Antibodies and Cancer Ther-

apy (UCLA Symposia on Molecular and Cellular Biology, NewSeries, Vol 27), 1985, 930

Robinson JK: Fundamentals of Skin Biopsy, 1986, 932Rosalki SB, ed: Clinical Biochemistry of Alcoholism (Contem-

porary Issues in Clinical Biochemistry), 1984, 1047Rose NR, Mackay IR, eds: The Autoimmune Diseases, 1985, 1366Roth LM, Czemobilsky B, eds: Tumors and Tumorlike Conditions

of the Ovary (Contemporary Issues in Surgical Pathology),1985, 583

Royal College ofSurgeons of England Slide Atlas of Pathology (edJL Turk, CDM Fletcher), 8 vols, 1986, 1365

Scadding JG, Mitchell DN: Sarcoidosis, 2nd ed, 1985, 349Scarpelli DG, Craighead JE, Kaufman N, eds: The Pathologist and

the Environment (International Academy of Pathology Mono-graph), 1985, 699

Schmalbruch H, ed: Skeletal Muscle (Handbook of MicroscopicAnatomy, Vol 2, Part 6), 1985, 1367

Seitz HK, Kommerell B, eds: Alcohol Related Diseases in Gastro-enterology, 1985, 350

Serjeant GR: Sickle Cell Disease, 1986, 815Shepherd JH, Monaghan JM, eds: Clinical Gynaecological Oncol-

ogy, 985, 931Shu Y-J: The Cytopathology of Esophageal Carcinoma: Pre-

cancerous Lesions and Early Cancer, 1985, 1163Smith LH, Thier SO, eds: Pathophysiology: The Biological Prin-

ciples of Diseases, 2nd ed (International Textbook of Medicine,Vol 1), 1985, 931

Special Topics in Endocrinology and Metabolism, Vol 7, 1985, 815Stansfield AG, ed: Lymph Node Biopsy Interpretation, 1985, 699Taylor-Papadimitriou J, ed: Interferons: Their Impact in Biology

and Medicine, 1985, 349Tiwari JL, Terasaki PI: HLA and Disease Associations, 1985, 1163Triplett DA: Hemostasis: A Case Oriented Approach, 1985, 351Tumors and Pseudotumors of the Serous Membranes (Atlas ofTumor Pathology, 2nd series), 1985, 699

Tumors of the Urinary Bladder, Supplement (Atlas of TumorPathology, 2nd series), 1985, 351

Urinary Tract and the Catheter: Infection and other Problems, 1985,347

Whaley K, ed: Methods in Complementfor Clinical Immunologists,1985, 814

Whitehead R: Mucosal Biopsy of the Gastrointestinal Tract (MajorProblems in Pathology, Vol 3), 3rd ed, 1985, 466

Williams REO: Microbiology for the Public Health: The Evolutionof the Public Health Laboratory Service 1939-1980, 1985, 467

WoolfN: Cell, Tissue, and Disease: The Basis ofPathology, 2nd ed,1986, 1162

Wright R, et al, eds: Liver and Biliary Disease: Pathophysiology,Diagnosis, Management, 2nd ed, 1985, 350

Year Book of Pathology and Clinical Pathology, 1985, 1985, 348Young JA: Colour Atlas of Pulmonary Cytopathology (Oxford

Colour Atlases of Pathology), 1985, 351Books: new titles, 120, 352. 816Bordetella pertussis survival in transport media (L), 119BPL. See Beta-propiolactoneBrain, human, in Alzheimer's disease, monoclonal antibody (SMP)

binding to congophilic elements in, 1199macrophages and microglial cells labelled by monoclonal anti-

body to macrophages (EBM/1 1), 615

1378Breast abscess, non-puerperal, pathogenic role of Mobiluncus spp in

(L), 342-,carcinoma of, cytoprognostic classification in, value of, 489

ductal, in situ, endocrine variant of, ultrastructuraland light microscopical studies of 2 cases, 1355

,growth fractions determined in situ with monoclonalantibody Ki-67, 977

,with spread to lymph nodes, characterisation ofcan-cer cells with high malignant potential in, 603

-, sarcoidosis of, case of, 446tissue, benign and malignant, ras oncogene p21 product in,

immunohistochemical detection of, 428- tumours, frozen, oestrogen receptor assays using, quality con-

trol of (L), 690Bronchitis, chronic, and emphysema, right ventricular weight at nec-

ropsy in, comparison with interstitial pulmonary fibrosis, 594Bronchoalveolar lavage fluid, cytological examination of, diagnosis

of 15 cases of Pneumocystis carinii pneumonia by, 945Bronchus, carcinoma of, mimicking myocardial infarction, plasma

enzyme changes in (L), 1158-, -, squamous cell, poorly differentiated, light and elec-

tron microscopic study, 284

C4, serum concentrations in subjects with and without C4 null alleles,reference ranges for, 573

Ca antigen and urothelial antibacterial defences (L), 691Calcium homeostasis in second trimester fetuses, 838- reabsorption, renal tubular, in hypercalcaemia, clinical assess-

ment of, influence of urinary sodium excretion, 641Campylobacter, gastric, local immune response to, in non-ulcer dys-

pepsia, 863Campylobacter-like organisms and reflux gastritis, 531Campylobacter pyloridis and associated serum IgG and IgA antibody

responses in patients undergoing upper gastrointestinal endo-scopy, clinical importance of, 215-, detection in gastric mucosa by phase contrast microscopy,

112, gastritis, and peptic ulceration (Review article), 353, identification of, simplified techniques for (L), 1279

Candidosis, invasive, diagnosis of, serum arabinitol estimations for,842

Captopril and enalapril, severe cutaneous reactions to, histologicalstudy and comparison with early mycosis fungoides, 902

Carbamazepine, hypersensitivity to, presenting as pseudolymphoma,case of, 1224

Carcinoembyronic antigen expression in normal, chronicallyinflamed, and malignant pancreatic tissue, immunohistochemicaldemonstration of, 610

in serum, diagnostic accuracy in pancreatic cancer, com-parison with tissue polypeptide antigen, 75

Carcinoid, prostatic adenocarcinoma evolving into, 2 cases of, selec-tive effect of hormonal treatment?, 750

tumour, atypical, chronic ulcerative colitis complicated by, caseof, 913

Carcinoma, adenoma, and hyperplastic polyps, colonic, glycoproteinabnormalities shown by lectin peroxidase histochemistry, 1331

, cystic, adenoid, laminin and fibronectin in, 138of breast, cytoprognostic classification in, value of, 489-, ductal, in situ, endocrine variant of, ultrastructural

and light microscopical studies of 2 cases, 1355-, growth fractions determined in situ with monoclonal

antibody Ki-67, 977with spread to lymph nodes, characterisation of can-

cer cells with high malignant potential in, 603of bronchus mimicking myocardial infarction, plasma enzyme

changes in (L), 1158, squamous cell, poorly differentiated, light and elec-

tron microscopic study, 284-of lung, small cell, somatostatin and ACTH. like immu-

noreactivity in, 418

Subject indexof thyroid, anaplastic, small cell, differentiation from lymphoma

by immunocytochemistry (L), 231of upper urinary tract, transitional histological and cyto-

pathological study, 297, pancreatic, diagnosis of, comparison of accuracy of tissue poly-

peptide antigen and serum CEA in, 75parathyroid, nuclear diameter in, 1353rectal, lymphocytic infiltration and survival in, 585renal, central nervous system metastases of, and CNS hae-

mangioblastomas, differential diagnosis of, immunoperoxidaselabelled antibody staining in, 917

, serum amyloid A variations in, correlation with disease activity,stage, primary site, and prognosis, 794

Carcinomas and sarcomas, antineuron specific enolase staining reac-tions in, and lack of neuroendocrine specificity, 1186

Cardiac. See HeartCardiovascular and respiratory disease, pulmonary megakaryocytes

"missing link" between?, 969Catalase-negative Staphylococcus aureus (L), 695Cathepsin D in normal and neoplastic human tissues, immu-

nolocalisation of, 1323Catheters, Hickman, source of infection in (L), 1046Cations, monovalent and divalent, interactive roles in pathogenesis of

hypertension caused by alcohol, 1264Cefotetan, effects on haemostasis in 2 patients with reduced serum

vitamin K1 concentrations, 1245Central nervous system haemangioblastomas and CNS metastases of

renal carcinomas, differential diagnosis of, immunoperoxidaselabelled antibody staining in, 917

Centrifugation, high speed, in early detection of bacteraemia, 1157Centrorrhexis as term for "new" reaction pattern oflymph nodes (L),

1042Cephalosporins. See CefotetanCerebral and orbital Aspergillus infection due to invasive aspergillosis

of ethmoid sinus, case of, 774Cervical and oviductal epithelium, human, nature of "basal" and

"reserve" cells in, 306brush biopsy specimens suitable for DNA and oncoprotein anal-

ysis using flow cytometry, 577cytology, terminology in, definitions and recommendations

from British Society for Clinical Cytology Working Party (Reviewarticle), 933

glandular atypia associated with squamous intraepithelial neo-plasia, premalignant lesion?, 22

-intraepithelial neoplasia with associated human papillomavirus6 and 16 infections, histological and immunocytochemical study,1177

Chest infections, postoperative, especially Haemophilus influenzaeinfections, study of, 78

Chlamydia antigen detection, ELISA for, false positive results with(L), 1276

-detection by monoclonal antibody ELISA based technique andeffects of sample storage (L), 927

Chlamydia trachomatis antigen detection by enzyme immunoassay,immunofluorescence, and cell culture (L), 232-, chronic respiratory disease in premature infants caused by,

84; (L), 698urethritis detected by immunoblotting, antigenic specificity

of serological response in, 325Chlamydial endometritis, lymphoid reaction in case of (L), 464

infection, class specific immunoglobulin response to individualChlamnydia trachomatis polypeptides, elementary bodies, and retic-ulate bodies in, 1313

Cholecystitis, chronic and "minimal", gall bladders with, macro-phages and mast cells in, 1082

Chromium, technetium, and indium erythrocyte radiolabeiling, invitro comparison in undamaged and heat damaged cells, 717

Cirrhosis, biliary, primary, serum immunoreactive trypsin and pan-creatic lipase in, 638

Clinical biochemistry services, costing as part of operational manage-

Subject indexment budgeting system, 817

Clostridium difficile, detection and identification of, latex particleagglutination for, 212- in cystic fibrosis, asymptomatic carriage of, 1013

isolation from human jejunum and possible identificationof jejunum as reservoir for disease, 861

toxins, cytotoxicity assays for, technique for measuring50% end points in, 672

Coagglutination test in serotyping of Streptococcus pnewnoniaestrains, 328

Coagulase production by Staphylococcus aureus strains of differingresistance characters, comparison of 2 traditional tests with latexagglutination system (Staphaurex), 371

Coagulase-negative staphylococci in chronic ambulatory peritonealdialysis, production of slime by, clinical importance of (L), 117

Coagulopathy associated with meningococcal septicaemia, case of,1304

Cocci, anaerobic, Gram positive, survival on swabs and isolationfrom mouth and vagina, 93

Coccoid rods, anaerobic, antibody response to, in Crohn's disease,1130

Coconut matting bezoar identified by combined analytical approach,172

Colitis, ulcerative, chronic, complicated by atypical carcinoidtumour, case of, 913

, , long standing, value of mucin histochemistry in follow upsurveillance in, 393

Colon, carcinoma, adenoma, and hyperplastic polyps of, gly-coprotein abnormalities shown by lectin peroxidase histo-chemistry, 1331

-, polyps of, adenomatous, ploidy studies in (L), 695, 696, 1276Colorectal goblet cell sialomucin heterogeneity, relation to malignant

disease, 1088Colorectum, DNA content and adenoma-carcinoma sequence in, 387Complement. See C4Computer. See MicrocomputerConception, products of. See FetusesCondyloma acuminata of anus, human papilloma virus in (L), 927Coronavirus, enteric, in symptomless homosexuals (L), 1159Corrections, 236, (L), 465, 816, 932, 1048Coryneforms group JK, antibiotic resistant, biochemical and cultural

characteristics of, 654C-reactive protein concentration in suspected bacteraemia (L), 1363

serial concentrations as indicator of urinary tract infectionin spinal injury, 851

Crohn's disease, antibody response to anaerobic coccoid rods in, 1130-, lamina propria mast cells in biopsies from children with,

279Cryostat section assay of oestrogen and progesterone receptors in

meningiomas, clinicopathological study, 44Cryptosporidial infection, screening for (L), 1363Cryptosporidium sp (L), 465 (Errata)Cushing's syndrome, ectopic, 18 tumours causing, immu-

nocytochemical study of, 955Cutaneous non-Hodgkin's lymphomas other than mycosis fungoides,

immunocytochemical characterisation of, 553-reactions, severe, to captopril and enalapril, histological study

and comparison with early mycosis fungoides, 902Cyclosporin A, renal allograft recipients immunosuppressed with,

yellow and blue-green fluorescence in renal tubular cells, red bloodcells, and lymphocytes in urinary sediments of (L), 116

-and renal graft histology, 145nephrotoxicity in renal allografts, morphological differentiation

from rejection, 152Cystic carcinoma, adenoid, laminin and fibronectin in, 138

fibrosis, Clostridium difficile in, asymptomatic carriage of, 1013-, Pseudomonas aeruginosa from, inhibition by selective

media, 220, serum antibodies to Pseudomonas aeruginosa cell surface

antigens in, development of ELISA for detection of, 1124

1379mesothelioma, peritoneal, electron microscopic and immu-

nohistochemical study of 2 men with, 440Cysts, theca-lutein, ovarian, gestational trophoblastic disease compli-

cated by, abnormal steroid excretion in, 627Cytokeratin and epithelial membrane antigen expression by meningi-

omas, immunohistological study, 435, common leucocyte, and other markers in immunohistochemical

diagnosis of tumours on routine surgical sections, 514Cytology, cervical, terminology in, definitions and recommendations

from British Society for Clinical Cytology Working Party (Reviewarticle), 933

Cytomegalovirus DNA, restriction enzyme analysis of, for study oftransmission of infection, 318

inclusion disease and sudden infant death, 383Cytoplasmic fibrils, bundles of, in 50 cases of acute myeloid leu-

kaemia, correlation with nuclear morphology, 99

Data coding, manual, with SNOP or SNOMED systems, comparisonof errors in 2 hospitals, 622

Delta virus. See Hepatitis delta virusDementia, senile, of Alzheimer type and aging, effects on dihydro-

pteridine reductase activity in dried blood spots, 199Deoxyuridine suppression test, new micro method for, 1155DF-2, septicaemia and meningitis caused by, case of, 1021Diabetes mellitus, erythrocyte deformability in, effects of hyper-

glycaemia and sorbitol accumulation, 722Dialysis, peritoneal, ambulatory, chronic, coagulase negative staphy-

lococci in, production of slime by, clinical importance of (L), 117-9 1,-, continuous, peritonitis in, laboratory diagnosis bylysis and centrifugation, 925

Dihydropteridine reductase activity in dried blood spots, effects ofaging and senile dementia of Alzheimer type, 199

Dipeptidyl aminopeptidase II and IV in normal and malignant hae-mic cells, comparative cytochemical study, 891

Dipstick analysis for paediatric urine screening, 1360DNA analysis in human disease (Review article), 1281

and oncoprotein analysis using flow cytometry, cervical brushbiopsy specimens suitable for, 577

content and adenoma-carcinoma sequence in colorectum, 387-,cytomegalovirus, restriction enzyme analysis of, for study of

transmission of infection, 318flow cytometry in non-Hodgkin's lymphomas, prognostic

importance of, 542ploidy patterns and cytokinetics of non-Hodgkin's lymphoma,

987probes, biotinylated, hybridised in situ, visualisation of (L), 230

Dyserythropoietic anaemia, type I, congenital, erythroblast functionin 2 patients with, evidence of impaired DNA, RNA, and proteinsynthesis and other abnormalities, 881

Dysgonic fermenter-2. See DF-2Dyspepsia, non-ulcer, local immune response to gastric Cam-

pylobacter in, 863

E rosette inhibitory substance in serum and T lymphocyte numbers(L), 231

Eccrine poroma, malignant, 3 cases of, 1099Electron and light microscopic study of poorly differentiated squa-mous carcinoma of bronchus, 284

-of scar adenocarcinoma of lung, 423microscopy, analytical, asbestos fibre dust counts in

lung tissue obtained by, comparison of results, 313microscopic and immunohistochemical study of 2 men with

peritoneal cystic mesothelioma, 440ELISA based monoclonal antibody technique for detection of Chla-

mydia and effects of sample storage (L), 927-for detection of chlamydia antigen, false positive results with

(L), 1276for detection of serum antibodies to Pseudomonas aeruginosa

cell surface antigens in cystic fibrosis, development of, 1124Emphysema and chronic bronchitis, right ventricular weight at nec-

1380ropsy in, comparison with interstitial pulmonary fibrosis, 594

Enalapril and captopril, severe cutaneous reactions to, histologicalstudy and comparison with early mycosis fungoides, 902

Encephalitis, herpes, viral localisation in, and human and viral genedetection in paraffin embedded tissue by in situ hybridisation withbiotinylated probes, 1066

Endocrine variant of ductal carcinomas in situ of breast, ultra-structural and light microscopical studies of 2 cases, 1355

Endometrial cytology, diagnostic criteria based on composition andarchitecture of large tissue fragments in smears for, 36

Endometritis, chlamydial, lymphoid reaction in case of (L), 464Endoproteases, pancreatic, and pancreatic secretory trypsin inhibitor

immunoreactivity in Paneth cells, 786Enolase, neuron specific. See Neuron specific enolaseEnteric coronavirus in symptomless homosexuals (L), 1159Enterobacteriaceae and other Gram negative rods, low cost

identification in clinical laboratories, construction of database for,798

Enzyme immunoassay, immunofluoresence, and cell culture fordetection of Chiamydia trachomatis antigen (L), 232

Enzyme-linked immunosorbent assay. See ELISAEosinophilic gastroenteritis (L), 696

infiltrates of gastrointestinal tract (Review article), 1Epidermis and other epithelial cells, comparison ofHTLV-I antibody

(12/1-2) reactivity in, 547Epididymis, isolated arteritis of (L), 114Epithelial cells from epidermis and elsewhere, comparison of HTLV-

I antibody (12/1-2) reactivity in, 547membrane antigen and cytokeratin expression by meningiomas,

immunohistological study, 435-, fibronectin, and laminin, antisera to, study of child-

hood renal tumours using, 51tumours, malignant, associated with autoimmune sialadenitis, 2

British cases of, 497Epstein-Barr virus infection, fatal case of, lymphoproliferative lesions

in, immunohistological studies, 1317Erythroblast function in 2 patients with congenital dyserythropoietic

anaemia, type I, evidence of impaired DNA, RNA, and proteinsynthesis and other abnormalities, 881

Erythroblastopenia in iron deficiency anaemia, human parvovirusassociated with (L), 1277

Erythrocyte antioxidative enzyme activities, comparison between 2types of haemoglobin H disease, 1296

-deformability in diabetes mellitus, effects of hyperglycaemia andsorbitol accumulation, 722

radiolabelling with chromium, technetium, and indium, in vitrocomparison in undamaged and heat damaged cells, 717

-. See also Red cellErythrocytes, "'1In labelling of, clinical use in haemolytic anaemias

(L), 464Erythrocytic multinuclearity, hereditary, with positive acidified

serum (Hams) test. See HEMPASEscherichia coli, Bacteroides sp, and polymorphonuclear leucocytes,

interactions between, role in pathogenesis of mixed infection, 376-meningitis and Strongyloides stercoralis hyperinfestation

syndrome, 2 cases of, 366Ethmoid sinus, invasive aspergillosis of, cerebral and orbital Asper-

gillus infection due to, case of, 774Eyes, identification of non-capsulate strains of Streptococcus pneu-

moniae isolated from, 871of neonates, sticky, indifferent streptococci in (L), 116

Fatty acids, free, hepatic, raised, in patient with acute fatty liver aftergastric surgery for morbid obesity, 647

Femur, neck of, fractured, and contralateral intracerebral lesions, 920Ferritin, serum concentration in sickle cell crisis, 253Fetuses, aborted, prenatal diagnosis, examination of terminated

specimens and description of anomalies (Review article), 1049, second trimester, calcium homeostasis in, 838

Fibrils, cytoplasmic, bundles of, in 50 cases of acute myeloid leu-

Subject indexkaemia, correlation with nuclear morphology, 99

Fibrin polymerisation, laster nephelometry measurement of, 227Fibrinogen, activation of platelet aggregation mediated by (L), 344Fibronectin and laminin in adenoid cystic carcinoma, 138

, laminin, and epithelial membrane antigen, antisera to, study ofchildhood renal tumours using, 51

Filaments, intermediate, different classes of, coexpression by humanlung tumours, 950

Flow cytometry, DNA and oncoprotein analysis using, cervical brushbiopsy specimens suitable for, 577- for DNA in non-Hodgkin's lymphomas, prognostic

importance of, 542Fluorescence study of blood group antigen expression in urinary tract

tumours using cryostat sections of fresh frozen tissues, 1165Formalin pigment removal, effect on peroxidase-antiperoxidase

immunoperoxidase technique, 9233-Fucosyl-N-acetyllactosamine in Reed-Sternberg cells demonstrated

by monoclonal antibody (AGF 4 48), 564

Gall bladders with chronic and "minimal" cholecystitis, macrophagesand mast cells in, 1082

Gas, arterial blood, analysis of, effect of sodium citrate anticoagulantin vitro on results of (L), 1046

capture (Oxoid) system for blood cultures, comparison withBactec radiometric system, 661

Gastric Campylobacter, local immune response to, in non-ulcer dys-pepsia, 863

mucosa, detection of Campylobacter pyloridis by phase contrastmicroscopy in, 112

surgery for morbid obesity, acute fatty liver after, raised hepaticfree fatty acids in patient with, 647

Gastritis, peptic ulceration, and Campylobacter pyloridis (Reviewarticle), 353

reflux, and Campylobacter-like organisms, 531,- ,as distinct histopathological entity, 524

Gastroenteritis, eosinophilic (L), 696Gastrointestinal endoscopy, upper, Campylobacter pyloridis and

associated serum IgG and IgA antibody responses in patientsundergoing, clinical importance of, 215

tract, eosinophilic infiltrates of (Review article), IGene detection, human and viral, in paraffin embedded tissue by in

situ hybridisation with biotinylated probes and viral localisation inherpes encephalitis, 1066

Genetic disease, human, DNA analysis in (Review article), 1281Giant cells, morphological characteristics of, and necropsy findings in

case of acute idiopathic interstitial myocarditis, 1209Giemsa stain and Gomori's methenamine silver nitrate in simulta-

neous demonstration of Pneumocystis carinii cyst walls and intra-cystic bodies in paraffin embedded lung sections, 1269

Glisson's capsule, pseudolipoma of, simulating metastatic tumour,case of (L), 345

Globin chain synthesis in reticulocytes, increased a:non-a ratios inmyelodysplastic syndromes and myeloid leukaemia, 1233

Glomerulonephritis, membranous, 167, idiopathic, effects of geographical differences, 1193

Glycoprotein abnormalities in colonic carcinomata, adenomata, andhyperplastic polyps shown by lectin peroxidase histochemistry,1331

ct2-Glycoprotein, "pregnancy-associated", in serum, deficiency of,association with disease, 195

Goblet cells, colorectal, sialomucin heterogeneity in, relation tomalignant disease, 1088

Gomori's methenamine silver nitrate and Giemsa stain in simulta-neous demonstration of Pneumocystis carinii cyst walls and intra-cystic bodies in paraffin embedded lung sections, 1269

Gram-negative aerobic bacilli, identification of, kit systems for(Welsh Standing Specialist Advisory Working Group in Micro-biology report), 666

Gram-positive anaerobic cocci, survival on swabs and isolation frommouth and vagina, 93

Subject indexGranuloma, plasma cell, of thyroid, case of, 1105Guanidine hydrochloride as reagent for selective inhibition in quan-

titative method for determining serum alkaline phosphatase iso-enzyme activity, 1025, 1031

H6000, lymphocyte recovery rate using (L), 234Haemagglutination kit, Serodia, for HBe, micromodification of, and

modification of kit to test for anti-HBe, 332test, passive, for serological diagnosis of typhoid fever in

endemic area, comparison with Widal agglutination test, 680Haemangioblastomas of central nervous system and CNS metastases

of renal carcinomas, differential diagnosis of, immunoperoxidaselabelled antibody staining in, 917

Haemic cells, normal and malignant, dipeptidyl aminopeptidase IIand IV in, comparative cytochemical study, 891

Haemochromatosis, idiopathic, and HLA antigens in Italy, with A3Bw35 HLA haplotype as marker for idiopathic haemochromatosisgene in NE regions, 125

Haemoglobin electrophoresis, effect of beta-propiolactone (L), 814H disease, comparison of erythrocyte antioxidative enzyme

activities between 2 types of, 1296Haemolytic anaemia, immune, and nomifensine treatment, 6 cases inNW England (1984-85), 1147

anaemias, clinical use of ...In labelling of red cells in (L), 464uraemic syndrome, classification of (L), 812

Haemophilus influenzae and other postoperative chest infections,study of, 78-antimicrobial susceptibility testing, trial for UK national

external quality assessment scheme for microbiology, 1006, biotyping of, comparison of API-lOS strips and tube tests

for (L), 692Haemopoiesis, extramedullary, intestinal, and acute small bowel

obstruction, myelofibrosis complicated by, case of, 677Haemostasis in 2 patients with reduced serum vitamin K, concen-

trations, effects of cefotetan, 1245Hageman factor, high molecular weight kininogen and prekallikrein

in chronic liver disease, 1003Head injury, non-missile, pituitary gland abnormalities in, analysis in

100 consecutive cases, 769Heart disease, congenital, demonstration by inflation and wax

impregnation technique, 503, ischaemic, acute, serum amyloid A concentrations during

course of, 635diseases, aetiology of, role of toxoplasmosis in, immu-

nobiological investigation, 204- transplants, Toxoplasma gondii infections in recipients of, sero-

logical diagnosis problems in, 1135HEMPAS, parvovirus infection associated with aplastic crisis in

patient with, 1019Hepatic tumours and tumour like conditions, benign, in men, 183

vein lesions in alcoholic liver disease, retrospective biopsy andnecropsy study, 63

Hepatitis A virus infection as disease of Kupffer cells (L), 1160B surface antigen, antibody to, donor screening for (L), 583

virus particles, concentration of, rapid method using Beck-man airfuge, 808

Be haemagglutination kit, Serodia, micromodification of, andmodification of kit to test for anti-HBe, 332

delta virus, chronic liver disease caused by, autoimmunity in,897

Herpes encephalitis, viral localisation in, and human and viral genedetection in paraffin embedded tissue by in situ hybridisation withbiotinylated probes, 1066

Hickman catheters, source of infection in (L), 1046High molecular weight kininogen, Hageman factor, and prekallikrein

in chronic liver disease, 1003Hip joint replacement specimens, cemented, plastic processing of, 339Histiocytosis, malignant, complicating rheumatoid arthritis, 4 cases

of, 16of intestine, malignant, immunophenotype analysis of, 8

1381Histopathological specimens, large format, examination and record-

ing of (L), 690HIV infection. See AIDSHLA antigens and idiopathic haemochromatosis in Italy, with A3

Bw35 HLA haplotype as marker for idiopathic haemochromatosisgene in NE regions, 125

Hodgkin's disease, diagnosis of, use of Leu Ml and antiepithelialmembrane antigen monoclonal antibodies for, 267

Homosexuals, symptomless, enteric coronavirus in (L), 1159HTLV-I. See Human T lymphotrophic retrovirusHTLV-III antibody, AIDS and anti-HTLV-III positive laboratory

reagents (L), 346infection and "high risk" labelling of specimens, time for

rethinking? (L), 114; (L), 811Human immunodeficiency virus infection. See AIDS

T cell leukaemia virus. See HTLVT lymphotrophic retrovirus antibody (12/1-2), reactivity of,

comparison between epidermis and other epithelial cells, 547Hypercalcaemia in T cell acute lymphoblastic leukaemia, 2 cases of,

1143,renal tubular calcium reabsorption in, clinical assessment of,

influence of urinary sodium excretion, 641Hyperglycaemia and sorbitol accumulation, effects on erythrocyte

deformability in diabetes mellitus, 722Hypertension caused by alcohol, interactive roles of monovalent and

divalent cations in pathogenesis, 1264Hypothyroidism, strategy for testing thyroid function applied to,

evaluation of, 293; (L), 1278

Image analysis, semiautomatic, in morphometry of spermatozoa,1347

Immune deficiency syndrome, acquired. See AIDSresponse, local, to gastric Campylobacter in non-ulcer dyspepsia,

863Immunoblot analysis of serological response to Pseudomonas

aeruginosa septicaemia, 1306Immunoblotting, Chlamydia trachomatis urethritis detected by, anti-

genic specificity of serological response in, 325Immunocytochemical characterisation of cutaneous non-Hodgkin's

lymphomas other than mycosis fungoides, 553- labelling with antibody Ki67 for assessment of lung tumours,

590-staining for identification of cells in peritoneal fluid and wash-

ings at laparoscopy and laparotomy, 1335-study of 18 tumours causing ectopic Cushing's syndrome, 955Immunofluorescence, anticomplement, for antibody titration,

importance for diagnosis of varicella-zoster virus infection in Bell'spalsy, 1254

test, commercial, for identification of Legionella pneumophila(L), 693

Immunoglobulin A deficiency, latex agglutination method for, inlarge scale screening of blood donor sera, 458

deposition in alcoholic liver disease, 1181G and A antibody responses in serum associated with Cam-

pylobacter pyloridis in patients undergoing upper gastrointestinalendoscopy, clinical importance of, 215

subclasses, distribution in anti-A and anti-B sera, 684heavy chains, distribution in diseased synovia, 731M, human parvovirus (B19) specific, in antigen positive serum

(L), 118preparations, intravenous, opsonic activity against Staphy-

lococcus epidermidis, 856response, class specific, to individual Chlamydia trachomatis

polypeptides, elementary bodies, and reticulate bodies in chla-mydial infection, 1313

Immunogold-silver technique demonstrating benign and malignant(B cell) focal lymphoid aggregates in bone marrow trephines, 453

Immunohistochemical analysis of mononuclear cell subsets ininflammatory and non-inflammatory myopathies, 271and electron microscopic study of 2 men with peritoneal cystic

1382mesothelioma, 440

demonstration of carcinoembryonic antigen expression in nor-mal, chronically inflamed, and malignant pancreatic tissue, 610

detection of ras oncogene p21 product in benign and malignantmammary tissue, 428

-diagnosis of tumours on routine surgical sections using cyto-keratin, common leucocyte, and other markers, 514

Immunohistological analysis of case of metastatic thymoma, 275studies of lymphoproliferative lesions in fatal case of Epstein-

Barr virus infection, 1317study of epithelial membrane antigen and cytokeratin expres-

sion by meningiomas, 435Immunolocalisation of cathepsin D in normal and neoplastic human

tissues, 1323Immunoperoxidase labelled antibody staining in differential diagno-

sis of central nervous system haemangioblastomas and CNSmetastases of renal carcinomas, 917

, peroxidase-antiperoxidase immunoperoxidase technique, effectof formalin pigment removal, 923

staining and monoclonal antibody in detection of group B strep-tococcal antigen in necropsy specimens, 223

study of new marker for mesothelioma, 961Immunophenotype analysis of malignant histiocytosis of intestine, 8Immunoreactivity of Reed Stemnberg cells in paraffin and frozen sec-

tions (L), 1043Indium, chromium, and technetium erythrocyte radiolabelling, in

vitro comparison in undamaged and heat damanged cells, 717lndium labelling of red cells, clinical use in haemolytic anaemias(L), 464

Infant death syndrome, sudden, and cytomegalovirus inclusion dis-ease, 383

Infants, premature, chronic respiratory disease caused by Chlamydiatrachomatis in, 84; (L), 698

Interferon treatment and bone marrow necrosis (L), 1045Interstitial myocarditis, idiopathic, acute, necropsy findings in case

of, and morphological characteristics of giant cells (L), 1209Intestinal extramedullary haemopoiesis and acute small bowel

obstruction, myelofibrosis complicated by, case of, 677lymphangiectasia, impaired neutrophil function in, 876spirochaetes, isolation and characterisation of, 535

Intestine, small, adenomatosis of, case of, 981Intestines, histiocytosis of, malignant, immunophenotype analysis of,

8Intracerebral lesions, contralateral, and fractured neck of femur, 920Iron deficiency anaemia, erythroblastopenia in, human parvovirus

associated with (L), 1277state in a and ,B thalassaemia trait, 256

Isoamylases in serum and liver diseases (L), 464Italy, idiopathic haemochromatosis and HLA antigens in, with A3

Bw35 HLA haplotype as marker for idiopathic haemochromatosisgene in NE regions, 125

Jejunum, human, isolation of Clostridium difficile from, and possibleidentification of jejunum as reservoir for disease, 861

Kaposi's sarcoma, histogenesis of, in patients with and withoutAIDS, 742

in AIDS, 469Karyotypes, G banded, in myeloma cells, analysis of, 260Keratocysts, odontogenic, fluids from, protein apparently specific to,

recognition of, 1108Kikuchi's disease. See Lymphadenitis, necrotisingKininogen, high molecular weight. See High molecular weight kinin-

ogenKupffer cells, hepatitis A virus infection as disease of (L), 1160Kveim suspension, intradermal injection of, early cellular responses

to, in normal subjects and in sarcoidosis, 176

Laboratories, clinical, communication in, program ("Mailbox") forimprovement of, 828

Subject indexLaboratory safety and "high risk" labelling of specimens, time for

rethinking? (L), 114; (L), 811(I Lactamase, "non-pathogens" producing, in chronic obstructive

airways disease, detection and importance of (L), 343Lamina propria mast cells in biopsies from children with Crohn's

disease, 279Laminin and fibronectin in adenoid cystic carcinoma, 138

, fibronectin, and epithelial membrane antigen, antisera to, studyof childhood renal tumours using, 51

Laparoscopy and laparotomy, cell identification in peritoneal fluidand washings at, immunocytochemical staining for, 1335

Larynx, mast cell sarcoma of, case of, 596Laser ion mass analyser in diagnosis of chronic beryllium disease, 900- nephelometry measurement of fibrin polymerisation, 227Latex agglutination method for IgA deficiency in large scale screening

of blood donor sera, 458system (Staphaurex) for testing coagulase production by

Staphylococcus aureus strains, comparison with 2 traditional meth-ods, 371

particle agglutination for detection and identification of Clostri-dium difficile, 212

Lectin peroxidase histochemistry in demonstration of glycoproteinabnormalities in colonic carcinomata, adenomata, and hyper-plastic polyps, 1331

Lectins, peroxidase conjugated, in study of childhood renal tumours,736

Legionella pneumophila, identification with commercialimmunofluorescence test (L), 693

Leucocyte common antigen, cytokeratin, and other markers in immu-nohistochemical diagnosis of tumours on routine surgical sections,514

Leucocytes, polymorphonuclear, Bacteroides sp, and Escherichia coli,interactions between, role in pathogenesis of mixed infection, 376

Leukaemia, acute, transformation of essential thrombocythaemia to,2 cases of, 1301

, biphenotypic (mixed acute T lymphoblastic and acutemyeloblastic leukaemia) (L), 343

, lymphoblastic, acute, myeloblastic syndrome coexisting with,case of, 728

T cell, hypercalcaemia in, 2 cases of, 1143terminal deoxynucleotidyl transferase positive cells

in testicular biopsy specimens from boys with, 1236, , childhood, French American British (FAB) mor-

phological classification of, clinical importance of, 998lymphocytic, chronic, autoimmunity in, 713myeloblastic, acute, Auer rods in, crystal structure of, 569myeloid, acute, correlations between nuclear morphology and

bundles of cytoplasmic fibrils in 50 cases of, 99, and myelodysplastic syndromes, increased reticulocyte

a:non-a globin chain synthesis ratios in, 1233Light and electron microscopic study of poorly differentiated squa-mous carcinoma of bronchus, 284

- of scar adenocarcinoma of lung, 423- microscopy, analytical, asbestos fibre dust counts in

lung tissue obtained by, comparison of results, 313chains, urinary, in myelomatosis, isoelectric points of, analysis

in relation to nephrotoxicity, 833Lipase, pancreatic, and immunoreactive trypsin in serum in primary

biliary cirrhosis, 638Liver and a;-antitrypsin, results of routine immunohistological

screen, 58-biopsies, PLP fixation for combined routine histology and

immunocytochemistry, 459-cytology, wash off, as complementary diagnostic tool to liver

biopsy, 449disease, alcoholic, hepatic vein lesions in, retrospective biopsy

and necropsy study, 63, IgA deposition in, 1181

-and serum isoamylases (L), 464, chronic, caused by hepatitis delta virus, autoimmunity in,

897

Subject indexHageman factor, high molecular weight kininogen,

and prekallikrein in, 1003,fatty, acute, after gastric surgery for morbid obesity, raised

hepatic free fatty acids in patient with, 647pseudotumour of, inflammatory, 5 cases of, 761See also Hepatic

Lung, carcinoma of, small cell, somatostatin and ACTH like immu-noreactivity in, 418

,fine needle aspiration cytology of, experience with cell blocktechnique in (L), 114

, scar adenocarcinoma of, light and electron microscopic study,423

-sections, paraffin embedded, Pnewnocystis carinii cyst walls andintracystic bodies in, simultaneous demonstration with Gomori'smethenamine silver nitrate and Giemsa stain, 1269

tissue, asbestos fibre dust counts obtained by analytical electronand light microscopy in, comparison of results, 313

tumours, assessment by immunocytochemical labelling withantibody Ki67, 590

, human, coexpression of different classes of intermediatefilaments by, 950

See also PulmonaryLupus nephritis, clinicopathological study of 162 cases in Thailand,

160Lymph node imprint in rapid diagnosis of lymph node biopsy speci-

mens, evaluation of, 688nodes, breast carcinoma with spread to, characterisation ofcan-

cer cells with high malignant potential in, 603"centrorrhexis" as term for "new" reaction pattern of (L),

1042Lymphadenitis, necrotising, without granulocytic infiltration (Kiku-

chi's disease) (L), 811, 812Lymphadenopathy, angioimmunoblastic, monoclonal T cell prolif-

eration in, evidence for, 1229Lymphangiectasia, intestinal, impaired neutrophil function in, 876Lymphoblastic leukaemia, acute, myeloblastic syndrome coexisting

with, case of, 728-, T cell, hypercalcaemia in, 2 cases of, 1143-,terminal deoxynucleotidyl transferase positive cells

in testicular biopsy specimens from boys with, 1236- ,childhood, French American British (FAB) mor-

phological classification of, clinical importance of, 998. See also T lymphoblastic

Lymphocyte infiltration and survival in rectal cancer, 585recovery rate using H6000 (L), 234See also T cell (s)

Lymphocytic leukaemia, chronic, autoimmunity in, 713Lymphoid aggregates, focal, benign and malignant (B cell), in bone

marrow trephines demonstrated by immunogold-silver technique,453

reaction in case of chlamydial endometritis (L), 464tissue, normal, Reed Stemnberg associated antigen Ki-l positive

cells in, high proliferative activity of, 993Lymphoma, differentiation from small cell anaplastic carcinoma of

thyroid by immunocytochemistry (L), 231, T cell, marrow involvement with, 3 cases initially presenting as

abnormal myelopoiesis, 134Lymphomas, non-Hodgkin's, cutaneous, other than mycosis fun-

goides, immunocytochemical characterisation of, 553,DNA flow cytometry in, prognostic importance of, 542

ploidy patterns and cytokinetics, 987Lymphoproliferative lesions in fatal case of Epstein-Barr virus infec-

tion, immunohistological studies, 1317Lysis filtration as adjunct to conventional blood culture, evaluation

of, 89

Macrophages and mast cells in gall bladders with chronic and "min-imal" cholecystitis, 1082and microglial cells in brain labelled by monoclonal antibody to

macrophages (EMB/ I1), 615

1383Malignant disease, relation to colorectal goblet cell sialomucin het-

erogeneity, 1088Marrow. See Bone marrowMast cell sarcoma of larynx, case of, 596

cells and macrophages in gall bladders with chronic and "min-imal" cholecystitis, 1082-of lamina propria in biopsies from children with Crohn's

disease, 279Megakaryocytes, pulmonary, "missing link" between cardiovascular

and respiratory disease?, 969Melanocytic naevi, "dysplastic", proposed alternative terminology

and subclassification, 189-tumours, S1OO protein and neurone specific enolase in, mea-

surement using video image analysis, 1096Membranous glomerulonephritis, 167

-,idiopathic, effects of geographical differences, 1193Meningiomas, epithelial membrane antigen and cytokeratin expres-

sion by, immunohistological study, 435, oestrogen and progesterone receptors in, cryostat section assay

of, clinicopathological study, 44, progesterone receptors in, morphometric assessment of vascu-

larity and cellularity on near facsimile cryostat sections (L), 810Meningitis and septicaemia caused by dysgonic fermenter-2 (DF-2),

case of, 1021,bacterial, normocellular, 4 cases of (L), 694,E coli, and Strongyloides stercoralis hyperinfestation syndrome,

2 cases of, 366Meningococcal septicaemia, coagulopathy associated with, case of,

1304Mesoblastic nephroma, study of 38 cases, 508Mesothelioma, cystic, peritoneal, electron microscopic and immu-

nohistochemical study of 2 men with, 440,new marker for, immunoperoxidase study, 961of atrioventricular node, primary, causing sudden death, case of

(L), 926N-Methyl-thiotetrazole cephalosporins. See CefotetanMicrocomputer, use as aid in teaching of pathology, 1140Microglial cells and macrophages in brain labelled by monoclonal

antibody to macrophages (EBM/1 1), 615Micro-organisms, growth in blood cultures, detection of, novel

method for, 1259Microscopy, phase contrast, in detection of Campylobacter pyloridis

in gastric mucosa, 112Mobiluncus spp, pathogenic role in non-puerperal breast abscess (L),

342Monoclonal antibodies, human, use in flow cytometry for deter-

mination of Rh(D) genotype, 1039, Leu M I and antiepithelial membrane antigen, use for diag-

nosis of Hodgkin's disease, 267antibody (AGF 4.48) in demonstration of

3-fucosyl-N-acetyllactosamine in Reed-Sternberg cells, 564and immunoperoxidase staining in detection of group B

streptococcal antigen in necropsy specimens, 223ELISA based technique for detection of Chiamydia and

effects of sample storage (L), 927- (Ki-67), assessment of lung tumours by immuno-

cytochemical labelling with, 590-in determination in situ of growth fractions in breast

cancer, 977-(SMP) binding to congophilic elements in human

Alzheimer brain, 1199- to HTLV-I (12/1-2), reactivity of, comparison between epi-

dermis and other epithelial cells, 547-to macrophages (EBM/I 1), brain macrophages and micro-

glial cells labelled by, 615-(UCHLI) recognising normal and neoplastic T cells in

routinely fixed tissues, 399-T cell proliferation in angioimmunoblastic lymphadenopathy,

evidence for, 1229Mononuclear cell subsets in inflammatory and non-inflammatory

1384myopathies, immunohistochemical analysis of, 271

Mountaineering accidents in Scotland, necropsy study of (July1978-December 1983), 1217

Mouth and vagina, survival of Gram positive anaerobic cocci onswabs and isolation from, 93

Mucin histochemistry, value in follow up surveillance in long stand-ing ulcerative colitis, 393

Mucosa, gastric, detection of Campylobacter pyloridis by phase con-trast microscopy in, 112

Muscular pulmonary arteries, intima of, effects of age and smoking,1204

Mutation and disease, 1283Mycobacterium leprae, staining in epoxy resin sections, 111Mycosis fungoides, early, comparison with severe cutaneous reac-

tions to captopril and enalapril, 902Myeloblastic leukaemia, acute, and acute T lymphoblastic leukaemia,

mixed (biphenotypic leukaemia) (L), 343--, , Auer rods in, crystal structure of, 569

Myelodysplastic syndrome coexisting with acute lymphoblastic leu-kaemia, case of, 728syndromes and myeloid leukaemia, increased reticulocyte

a:non-a globin chain synthesis ratios in, 1233Myelofibrosis complicated by intestinal extramedullary haemopoiesis

and acute small bowel obstruction, case of, 677Myeloid leukaemia, acute, correlations between nuclear morphology

and bundles of cytoplasmic fibrils in 50 cases of, 99and myelodysplastic syndromes, increased reticulocyte

a:non-a globin chain synthesis ratios in, 1233Myeloma cells, G banded karyotypes in, analysis of, 260Myelomatosis, urinary light chains in, isoelectric points of, analysis

in relation to nephrotoxicity, 833Myelopoiesis, abnormal, marrow involvement with T cell lymphoma

initially presenting as, 3 cases of, 134Myeloproliferative disorders, chronic, working classification based

on histological, haematological, and clinical findings, 237Myocardial infarction, acute, diagnosis at necropsy (L), 1161

c,arcinoma of bronchus mimicking, plasma enzymechanges in (L), 1158

, suspected, request patterns for clinical biochemistry testsin, differences between British and Canadian cardiac care units,803

Myocarditis, interstitial, idiopathic, acute, necropsy findings in caseof, and morphological characteristics of giant cells, 1209

Myopathies, inflammatory and non-inflammatory, mononuclear cellsubsets in, immunohistochemical analysis of, 271

Naevi, atypical, prevalence in general pathology practice (L), 929,melanocytic, "dysplastic", proposed alternative terminology

and subclassification, 189Natriuretic peptide, atrial, immunoreactive, in atrial amyloid,

identification of (L), 581Neisseria gonorrhoeae, cryptic plasmid of, homology with plasmids

from N meningitidis and N lactamica, 1119Neonates, eyes of, sticky, indifferent streptococci in (L), 116

,Nigerian, and mothers at term, vitamin D nutrition in, 650Neoplasia, intraepithelial, cervical, squamous, cervical glandular

atypia associated with, premalignant lesion?, 22,with associated human papiliomavirus 6 and 16

infections, histological and immunocytochemical study, 1177Neoplastic human tissues, cathepsin D in, immunolocalisation of,

1323Nephroma, mesoblastic, study of 38 cases, 508Nephrotoxicity, analysis of isoelectric points of urinary light chains

in myelomatosis in relation to, 833Nervous system, central. See Central nervous systemNeuron specific enolase and S100 protein in melanocytic tumours,

measurement using video image analysis, 1096antiserum staining reactions in sarcomas and carcino-

mas and lack of neuroendocrine specificity, 1186Neutrophil function, impairment in intestinal lymphangiectasia, 876

Subject indexNigerian women, pregnant, at term and newborn infants, vitamin D

nutrition in, 650Nitrate reduction by bacteria, commercial strip test for (L), 118Nomifensine treatment and immune haemolytic anaemia, 6 cases inNW England (1984-85), 1147

Notices, 120,235,352,468,584,700,816,932,1048,1163, 1280,1367Nuclear diameter in parathyroid carcinomas, 1353

morphology in 50 cases of acute myeloid leukaemia, correlationwith bundles of cytoplasmic fibrils, 99

Obesity, morbid, acute fatty liver after gastric surgery for, raisedhepatic free fatty acids in patient with, 647

Odontogenic keratocyst fluids, protein apparently specific to, recog-nition of, 1108

Oestrogen and progesterone receptors in meningiomas, cryostat sec-tion assay of, clinicopathological study, 44

receptor assays using frozen breast tumours, quality control of(L), 690

Oncogenesis, DNA probes in, 1289Oncoprotein and DNA analysis using flow cytometry, cervical brush

biopsy specimens suitable for, 577Orbital and cerebral Aspergillus infection due to invasive aspergillosis

of ethmoid sinus, case of, 774Ovarian sex cord tumour with annular tubules, progesterone prod-

uction in case of, 29-theca-lutein cysts, gestational trophoblastic disease complicated

by, abnormal steroid excretion in, 627tumours, prognosis of, morphometric data, Figo stage, histolog-

ical type and grade for, 1340Oviductal and cervical epithelium, human, nature of "basal" and

"reserve" cells in, 306Oxidation. See antioxidative enzymeOxoid gas capture system for blood cultures, comparison with Bactec

radiometric system, 661Oxyphil cells in thyroid disease, uniform change in?, 908

Paediatric urine screening, dipstick analysis for, 1360Pancreatic cancer, diagnosis of, comparison of accuracy of tissue

polypeptide antigen and serum CEA in, 75-endoproteases and pancreatic secretory trypsin inhibitor immu-

noreactivity in Paneth cells, 786-lipase and immunoreactive trypsin in serum in primary biliary

cirrhosis, 638tissue, normal, chronically inflamed, and malignant, carcino-

embyronic antigen expression in, immunohistochemical demon-stration of, 610

Pancreatitis, necrotising, acute, clinical pathology of, 68Paneth cells, pancreatic endoproteases and pancreatic secretory tryp-

sin inhibitor immunoreactivity in, 786Papillomavirus, human, in condyloma acuminata of anus (L), 927-, -, types 6 and 16, infection with, cervical intraepithelial neo-

plasia associated with, histological and immunocytochemicalstudy, 1177

Parathyroid and adrenal autoantibodies, coexisting, rarity of (L), 813carcinomas, nuclear diameter in, 1353

Parvovirus (BI9 virus), human, IgM specific for, in antigen positiveserum (L), 118,human, associated with erythroblastopenia in iron deficiency

anaemia (L), 1277infection associated with aplastic crisis in patient with

HEMPAS, 1019Pathology teaching, use of microcomputer as aid in, 1140Peptic ulcer, gastritis, and Campylobacter pyloridis (Review article),

353Periodate-lysine-paraformaldehyde fixation for combined routine

histology and immunocytochemistry of liver biopsies, 459Peritoneal cystic mesothelioma, electron microscopic and immu-

nohistochemical study of 2 men with, 440dialysis, ambulatory, chronic, coagulase negative staphylococci

in, production of slime by, clinical importance of (L), 117

Subject indexfluid and washings at laparoscopy and laparotomy, cell

identification in, immunocytochemical staining for, 1335Peritonitis in continuous ambulatory peritoneal dialysis, laboratory

diagnosis by lysis and centrifugation, 925Peroxidase conjugated lectins in study of childhood renal tumours,

736Peroxidase-antiperoxidase immunoperoxidase technique, effect of

formalin pigment removal, 923Pilar tumour of scalp, metastasising, case of, 757Pituitary gland abnormalities in non-missile head injury, analysis in

100 consecutive cases, 769Plasma cell granuloma of thyroid, case of, 1105

enzyme changes in carcinoma of bronchus mimicking myo-cardial infarction (L), 1158

Plasmid, cryptic, of Neisseria gonorrhoeae, homology with plasmidsfrom N meningitidis and N lactamica, 1119

Plasminogen activator release from vein walls, in vitro stimulation byadrenaline, 1241

Plastic processing of cemented hip joint replacement specimens, 339Platelet aggregation, fibrinogen mediated activation of (L), 344

function, laboratory investigation of, methodology for (Reviewarticle), 701volume analysis for differential diagnosis ofthrombocytosis, 129

Ploidy studies in adenomatous polyps of colon (L), 695, 696, 1276PLP. See Periodate-lysine-paraformaldehydePnewnocystis carinii cyst walls and intracystic bodies in paraffin

embedded lung sections, simultaneous demonstration with Gom-ori's methenamine silver nitrate and Giemsa stain, 1269

pneumonia, diagnosis by cytological examination of bron-choalveolar lavage fluid in 15 cases, 945

Pneumonias, serum angiotensin converting enzyme in, 1250Polyps, adenomatous, of colon, ploidy studies in (L), 695, 696, 1276

,hyperplastic, carcinoma, and adenoma, colonic, glycoproteinabnormalities shown by lectin peroxidase histochemistry, 1331

Poroma, eccrine, malignant, 3 cases of, 1099Poster demonstrations, preparation with word processors, 338; (L),

1364"Pregnancy-associated" cx2-glycoprotein in serum, deficiency of,

association with disease, 195Pregnant Nigerian women at term and newborn infants, vitamin D

nutrition in, 650Prekallikrein, Hageman factor and high molecular weight kininogen

in chronic liver disease, 1003Prenatal diagnosis, examination ofterminated fetuses and description

of anomalies (Review article), 1049Progesterone and oestrogen receptors in meningiomas, cryostat sec-

tion assay of, clinicopathological study, 44production in case of ovarian sex cord tumour with annular

tubules, 29receptors in meningiomas, morphometric assessment of vascu-

larity and cellularity on near facsimile cryostat sections (L), 810Prostate and prostatic urethra, infarcts of, necropsy study of, 1221Prostatic adenocarcinoma evolving into carcinoid, 2 cases of, selec-

tive effect of hormonal treatment?, 750Protein apparently specific to odontogenic keratocyst fluids, recog-

nition of, 1108Pseudolipoma of Glisson's capsule simulating metastatic tumour,

case of (L), 345Pseudolymphoma, hypersensitivity to carbamazepine presenting as,

case of, 1224Pseudomonas aeruginosa cell surface antigens, serum antibodies to, in

cystic fibrosis, development of ELISA for detection of, 1124from cystic fibrosis, inhibition by selective media, 220

- septicaemia, serological response to, immunoblot analysisof, 1306

maltophilia, susceptibility testing of (L), 463Pseudotumour, inflammatory, of liver, 5 cases of, 761Pulmonary arteries, muscular, intima of, effects of age and smoking,

1204-,- , intimal component of, measurement of (L), 697

1385fibrosis, interstitial, right ventricular weight at necropsy in, com-

parison with chronic bronchitis and emphysema, 594megakaryocytes, "missing link" between cardiovascular and

respiratory disease?, 969See also Lung

Pyomyositis, non-tropical, case of, 1116Quality assessment, external, UK national scheme for microbiology,

trial of Haemophilus influenzae antimicrobial susceptibility testingfor, 1006

control of oestrogen receptor assays using frozen breast tumours(L), 690

Racial differences in red cell indices, 105; Erratum, 816Radioimmunoassay kit, new, for determination of urinary albumin at

low concentrations, assessment and comparison with radialimmunodiffusion, 1151

Radiometric (Bactec) system for blood cultures, comparison withOxoid gas capture system, 661

Ras oncogene p21 product in benign and malignant mammary tissue,immunohistochemical detection of, 428

Rectal carcinoma, lymphocytic infiltration and survival in, 585Red cell indices, racial differences in, 105; Erratum, 816

. See also Erythrocyte(s)Reed-Stemnberg cells, antigen Ki- I positive cells in normal lymphoid

tissue associated with, high proliferative activity of, 993-, 3-fucosyl-N-acetyllactosamine demonstrated by mono-

clonal antibody (AGF 4-48) in, 564-, immunoreactivity in paraffin and frozen sections (L), 1043

Reflux gastritis and Campylobacter-like organisms, 531as distinct histopathological entity, 524

Renal allograft histology and cyclosporin, 145recipients immunosuppressed with cyclosporin A, yellow

and blue-green fluorescence in renal tubular cells, red blood cells,and lymphocytes in urinary sediments of (L), 116

allografts, morphological differentiation between rejection andcyclosporin nephrotoxicity in, 152

-carcinoma, central nervous system metastases of, and CNS hae-mangioblastomas, differential diagnosis of, immunoperoxidaselabelled antibody staining in, 917

tubular calcium reabsorption in hypercalcaemia, clinical assess-ment of, influence of urinary sodium excretion, 641

-tumours, childhood, study using antisera to fibronectin, laminin,and epithelial membrane antigen, 51

peroxidase conjugated lectins, 736Respiratory and cardiovascular disease, pulmonary megakaryocytes

"missing link" between?, 969disease, chronic, in premature infants caused by Chlamydia tra-

chomatis, 84; (L), 698Restriction enzyme analysis of cytomegalovirus DNA for study of

transmission of infection, 318Reticulocyte globin chain synthesis, increased a:non-a ratios in

myelodysplastic syndromes and myeloid leukaemia, 1233Rh(D) genotype determination, use ofhuman monoclonal antibodies

in flow cytometry for, 1039Rheumatoid arthritis complicated by malignant histiocytosis, 4 cases

of, 16

SIOO protein and neurone specific enolase in melanocytic tumours,measurement using video image analysis, 1096

Safety, laboratory, and "high risk" labelling of specimens, time forrethinking? (L), 114; (L), 811

Salivary glands, sublabial, histological changes due to aging processin, morphometric study of, 406

Sarcoidosis, early cellular responses to intradermal injection ofKveim suspension in, 176

-of breast, case of, 446Sarcoma, Kaposi's, histogenesis of, in patients with and withoutAIDS, 742

-, -, in AIDS, 469-,mast cell, of larynx, case of, 596

1386Sarcomas and carcinomas, antineuron specific enolase staining reac-

tions in, and lack of neuroendocrine specificity, 1186Scalp, pilar tumour of, metastasising, case of, 757Scar adenocarcinoma of lung, light and electron microscopic study,

423Senile dementia of Alzheimer type and aging, effects on dihydro-

pteridine reductase activity in dried blood spots, 199Septicaemia and meningitis caused by dysgonic fermenter-2 (DF-2),

case of, 1021meningococcal, coagulopathy associated with, case of, 1304Pseudomonas aeruginosa, serological response to, immunoblot

analysis of, 1306Serodia HBe haemagglutination kit, micromodification of, and

modification of kit to test for anti-HBe, 332Serum alkaline phosphatase isoenzyme activity, determination of,

quantitative method with guanidine hydrochloride, 1025, 1031amyloid A concentrations during course of acute ischaemic

heart disease, 635-variations in cancer, correlation with disease activity,

stage, primary site, and prognosis, 794angiotensin converting enzyme in pneumonias, 1250,anti-A and anti-B, distribution of immunoglobulin G sub-

classes in, 684,antigen positive, human parvovirus (BI9) specific IgM in (L),

118-arabinitol estimations for diagnosis of invasive candidosis, 842

*C4 concentrations in subjects with and without C4 null alleles,reference ranges for, 573CEA, diagnostic accuracy in pancreatic cancer, comparison

with tissue polypeptide antigen, 75E rosette inhibitory substance and T lymphocyte numbers (L),

231ferritin concentration in sickle cell crisis, 253IgG and IgA antibody responses associated with Campylobacter

pyloridis in patients undergoing upper gastrointestinal endoscopy,clinical importance of, 215

immunoreactive trypsin and pancreatic lipase in primary biliarycirrhosis, 638

isoamylases and liver diseases (L), 464"pregnancy-associated" a2-glycoprotein deficiency, association

with disease, 195vitamin K1 concentrations, reduced, haemostasis in 2 patients

with, effects of cefotetan, 1245Sex cord tumour, ovarian, with annular tubules, progesterone prod-

uction in case of, 29Sialadenitis, autoimmune, malignant epithelial tumours associated

with, 2 British cases of, 497Sialomucin heterogeneity in colorectal goblet cells, relation to malig-

nant disease, 1088Sickle cell crisis, serum ferritin concentration in, 253

-disease and thalassaemia intermedia, aplastic and hypo-plastic episodes in, 121

Small cell anaplastic carcinoma of thyroid, differentiation from lym-phoma by immunocytochemistry (L), 231

carcinoma of lung, somatostatin and ACTH like immu-noreactivity in, 418

Smoking and age, effects on intima of muscular pulmonary arteries,1204

Sodium, urinary excretion, influence on clinical assessment of renaltubular calcium reabsorption in hypercalcaemia, 641

Sodium citrate anticoagulant in vitro, effect on results of arterialblood gas analysis (L), 1046

Somatostatin and ACTH like immunoreactivity in small cell car-cinoma of lung, 418

Sorbitol accumulation and hyperglycaemia, effects on erythrocytedeformability in diabetes mellitus, 722

Spermatozoa, morphometry using semiautomatic image analysis,1347

Spinal injury, urinary tract infection in, C-reactive protein serialconcentrations as indicator of, 851

Subject indexSpirochaetes, intestinal, isolation and characterisation of, 535Squamous cell carcinoma of bronchus, poorly differentiated, light

and electron microscopic study, 284Staphylococci, coagulase-negative, in chronic ambulatory peritoneal

dialysis, production of slime by, clinical importance of (L), 117, , typing of, new method for, 1271

Staphylococcus aureus, catalase-negative (L), 695strains of differing resistance characters, coagulase prod-

uction by, comparison of 2 traditional tests with latex aggluti-nation system (Staphaurex), 371

epidermidis, opsonic activity of intravenous immunoglobulinpreparations against, 856

Steroid excretion, abnormal, in gestational trophoblastic diseasecomplicated by ovarian theca-lutein cysts, 627

Streptococci, indifferent, in sticky eyes of neonates (L), 116Streptococcus group B antigen, detection in necropsy specimens

using monoclonal antibody and immunoperoxidase staining, 223Streptococcus pneumoniae, non-capsulate strains isolated from eyes,

identification of, 871strains, serotyping by coagglutination, 328

Strongyloides stercoralis hyperinfestation syndrome with Escherichiacoli meningitis, 2 cases of, 366

Synovia, diseased, distribution ofimmunoglobulin heavy chains in,731

T cell acute lymphoblastic leukaemia, hypercalcaemia in 2 cases of,1143

lymphoma, marrow involvement with, 3 cases initiallypresenting as abnormal myelopoiesis, 134

numbers and serum E rosette inhibitory substance (L), 231-proliferation, monoclonal, in angioimmunoblastic lymph-

adenopathy, evidence for, 1229cells, normal and neoplastic, in routinely fixed tissues, mono-

clonal antibody (UCHLI) recognising, 399lymphoblastic leukaemia, acute, and acute myeloblastic leu-

kaemia, mixed (biphenotypic leukaemia) (L), 343Technetium, chromium, and indium erythrocyte radiolabelling, in

vitro comparison in undamaged and heat damaged cells, 717Technicon H601OC, simple reagent modification for processing of

uraemic samples, 1040Terminal deoxynucleotidyl transferase positive cells in testicular

biopsy specimens from boys with acute lymphoblastic leukaemia,1236

Thailand, lupus nephritis in, clinicopathological study of 162 cases,160

Thalassaemia intermedia and sickle cell disease, aplastic and hypo-plastic episodes in, 121

trait, a and f, iron state in, 256Theca-lutein cysts, ovarian, gestational trophoblastic disease compli-

cated by, abnormal steroid excretion in, 627Thrombocythaemia, essential, acute leukaemic transformation of, 2

cases of, 1301Thrombocytosis, differential diagnosis of, platelet volume analysis

for, 129Thymoma, metastatic, case with immunohistological analysis, 275Thyroid carcinoma, anaplastic, small cell, differentiation from lym-phoma by immunocytochemistry (L), 231

disease, oxyphil cells in, uniform change in?, 908-, fine needle aspiration of, confusion of subsequent histology due

to (L), 697, 698function testing strategy applied to hypothyroidism, evaluation

of, 293; (L), 1278gland, normal, histometry of, 475glands containing few and multiple nodules, histometry of, 483,plasma cell granuloma of, case of, 1105

Tissue polypeptide antigen, diagnostic accuracy in pancreatic cancer,comparison with serum CEA, 75

Toxoplasma gondii infections in heart transplant recipients, sero-logical diagnosis problems in, 1135

Toxoplasmosis, role in aetiology of cardiac disease, immu-nobiological investigation, 204

Subject indexTransplants, heart, Toxoplasma gondii infections in recipients of,

serological diagnosis problems in, 1135renal, histology of, and cyclosporin, 145

, morphological differentiation between rejection andcyclosporin nephrotoxicity in, 152,-, recipients immunosuppressed with cyclosporin A, yellow

and blue-green fluorescence in renal tubular cells, red blood cells,and lymphocytes in urinary sediments of (L), 116

Trophoblastic disease, gestational, complicated by ovarian theca-lutein cysts, abnormal steroid excretion in, 627

Trypsin, immunoreactive, and pancreatic lipase in serum in primarybiliary cirrhosis, 638

Tuberculosis, improved serodiagnosis using 2 assay test (antigen cap-ture immunoassay and antibody immunoassay), 779

Tumour, carcinoid, atypical, chronic ulcerative colitis complicatedby, case of, 913

, metastatic, pseudolipoma of Glisson's capsule simulating, caseof (L), 344

,pilar, of scalp, metastasising, case of, 757,sex cord, ovarian, with annular tubules, progesterone prod-

uction in case of, 29Tumours and tumour like conditions, hepatic, benign, in men, 183

causing ectopic Cushing's syndrome in 18 cases, immu-nocytochemical study of, 955

, diagnosis on routine surgical sections by immu-nohistochemistry using cytokeratin, common leucocyte, and othermarkers, 514

, epithelial, malignant, associated with autoimmune sialadenitis,2 British cases of, 497

-, melanocytic, SI00 protein and neurone specific enolase in, mea-surement using video image analysis, 1096

of breast, frozen, oestrogen receptor assays using, quality con-trol of (L), 690

of lung, assessment by immunocytochemical labelling with anti-body Ki67, 590

-human, coexpression of different classes of inter-mediate filaments by, 950

of urinary tract, blood group antigen expression in, fluorescencestudy using cryostat sections of fresh frozen tissues, 1165

, ovarian, prognosis of, morphometric data, Figo stage, histolog-ical type and grade for, 1340-9renal, childhood, study using antisera to fibronectin, laminin,and epithelial membrane antigen, 51

peroxidase conjugated lectins, 736Typhoid fever, serological diagnosis in endemic area, comparison of

passive haemagglutination test with Widal agglutination test for,680

Ulcer, peptic, gastritis and Campylobacter pyloridis (Review article),353

Uraemic samples, processing of, simple reagent modification ofTech-nicon H6010C for, 1040

Urethra, prostatic, and prostate, infarcts of, necropsy study of, 1221

1387Urethritis due to Chiamydia trachomatis detected by immu-

noblotting, antigenic specificity of serological response in, 325Urinary albumin determination at low concentrations, new radio-

immunoassay kit for, assessment and comparison with radialimmunodiffusion, 1151

infections, Gram negative, rapid diagnosis using identificationand antimicrobial susceptibility testing in 24 hours, 208

light chains in myelomatosis, isoelectric points of, analysis inrelation to nephrotoxicity, 833

sediments of renal allograft recipients immunosuppressed withcyclosporin A, yellow and blue-green fluorescence in renal tubularcells, red blood cells, and lymphocytes in (L), 116

sodium excretion, influence on clinical assessment of renaltubular calcium reabsorption in hypercalcaemia, 641

tract infection in spinal injury, C-reactive protein serial concen-trations as indicator of, 851

tumours, blood group antigen expression in, fluorescencestudy using cryostat sections of fresh frozen tissues, 1165

,upper, carcinoma of, transitional, histological and cyto-pathological study, 297

Urine screening, paediatric, dipstick analysis for, 1360specimens, culture and direct sensitivity testing of large numbers

of, technique for, 335Urothelial antibacterial defences and Ca antigen (L), 691

Vagina and mouth, survival of Gram positive anaerobic cocci onswabs and isolation from, 93

Varicella-zoster virus infection in Bell's palsy, diagnosis of,importance of anticomplement immunofluorescence antibodytitration for, 1254

Vein walls, plasminogen activator release from, in vitro stimulation byadrenaline, 1241

Ventricle, right, weight at necropsy compared in interstitial pul-monary fibrosis and in chronic bronchitis and emphysema, 594

Video image analysis in measurement of S100 protein and neuronespecific enolase in melanocytic tumours, 1096

Viral and human gene detection in paraffin embedded tissue by in situhybridisation with biotinylated probes and viral localisation inherpes encephalitis, 1066

Vitamin D nutrition in pregnant Nigerian women at term and new-born infants, 650

K1, serum concentrations, reduced, haemostasis in 2 patientswith, effects of cefotetan, 1245

Welsh Standing Specialist Advisory Working Group in Microbiologyreport on kit systems for identifying Gram-negative aerobic bacilli,666

White cell(s). See Leucocyte(s)Widal agglutination test for serological diagnosis of typhoid fever in

endemic area, comparison with passive haemagglutination test,680

Word processors in preparation of poster demonstrations, 338; (L),1364