Indian Institute of Technology Guwahati

Gautam Biswas, FNAIndian Institute of Technology Guwahati

1994 → 2014

Brief Profile of IIT GuwahatiDepartments1. Biotechnology 2. Chemical Engineering 3. Chemistry 4. Computer Science and Engineering5. Civil Engineering 6. Design7. Electronics and Electrical

Engineering 8. Humanities and Social Sciences 9. Mathematics10. Mechanical Engineering11. Physics

Interdisciplinary Academic Centres: 1. Nanotechnology2. Energy3. Environment

Total Students 4891

Under Grad. : 2509Post Grad. : 1062PhD : 1320

Faculty - 351

Professor : 91Associate Prof. : 95Assistant Prof. : 165

OfferingsBTechMSc – MA - MTechPhD, MTech-PhD (dual)

Mechanistic Approaches to Biology (MAB) Lab@ IITGCutting Edge Research

RNA BIOLOGY

Ribosome Assembly CRISPR Interference

Sensory &

Regulatory RNAs

Bioinformatics & Computational BiologyBiochemical Approaches

Fluorescence Spectroscopy

Macromolecular Crystallography

Molecular Genetics

Punetha A, Sivathanu R, Anand B, (2014) Active Site Plasticity Enables Metal Dependent Tuning

of Cas5d Nuclease Activity in CRISPR-Cas Type I-C System. Nucleic Acids Res., 42: 3846-3856.

Cutting Edge ResearchMicrobots – Nanobots – Superbots

CHEMOTAXIS

MAGNETOTAXIS

pH SENSOR

TRANSPOTERSmall, 9(11), 1916-20, 2013

Nanoscale, 6, 1398-1405, 2014

ELECTROPHORESIS

(2014), ACS Applied Materials & Interfaces, 6 (1), 712–724; (2013), PLOS One, PONE-D-13-38673R1 10.1371/journal.pone.0083877; (2014), Biomaterials Science, DOI: 10.1039/C3BM60251F

Suicide Gene

Therapy

Desired gene Cloning

Nanoparticles (Au, Ag, Cu, NC)

CD-UPRT, GMCSF, IkBα, INFγ

Targeted drug delivery, Antibacterial activity, Bio-

imaging Anti-cancer Activity

MALDI, CD, FACS,

Spectroscopy,

Nano-bio-technology

Protein Therapy

Cutting Edge Research: Cancer Therapeutics

Structural Tuning of MIL-53 (Al) to enhance CO2 uptake and Selectivity

•CO2 adsorption at >1 bar and 293 K

•CO2 desorption under vacuum at 293 K

Large pore form

Narrow pore formActivation of MIL-53(Al)

at 493 K under vacuum

Membrane for CO2 Capture from Flue Gas

Highlights• Novel poly(vinyl alcohol)-poly(vinyl pyrolidone) blend

membranes with amine carrier were synthesized for CO2 capture

• Highest CO2/N2 selectivity of 398 and CO2 permeance of 40 GPU were obtained Mishra et al., Langmuir , 29 (2013) 12162–12167

Cutting Edge Research CO2 Capture (IIT Guwahati-BHEL)

Why MIL-53(Al) ?

High temperature stability (up to 750 K) Does not degrade upon exposure to moisture Low enthalpy of adsorption Exhibits structural transformation

Novelty Effect of adsorption history on the structural transformation of MIL-53(Al) Narrow pore tuned from of MIL-53(Al) exhibits four fold enhancement (from

0.42 to 1.75 mol kg-1) in CO2 uptake at 0.17 bar and 293 K. It also show almost infinite selectivity for CO2 over CH4, N2, CO and O2 at sub-atmospheric pressure and 293 K

Cutting Edge ResearchPatient Trial of Polycentric Knee Joint

M40-R8/5/2014

M15-L13/5/2014

M75-L25/5/2014

M23-L3/2/2014

F8-L16/5/2014

Patient trial with polycentric knee joint

Testing of polycentric knee joint in amputee walking simulator

S. Kanagaraj et al. Mechanical characterization of PMMA/ SWNTs bone cement using Nanoindenter Materials Technology: Advanced

Biomaterials 29(B1), B4–B9, 2014

Cutting Edge ResearchSurface Acoustic Wave (SAW) Sensors

High sensitivity if operated in this region

Mode I Mode II Mode III

E0

TransmitterIDT

SignalConditioningCircuit

ReceiverIDT Sensing Film

Piezo-Substrate

RF Signal Generator

SAW sensor modified for high sensitivity

• N. Ramakrishnan, Roy Paily, and H. B. Nemade, Sensor Letters, vol. 8, no. 2, pp. 253–257, 2010.• N. Ramakrishnan, H. B. Nemade, and Roy Paily ,IEEE Sensors Journal, vol. 11, no. 2, pp. 430–431, 2010.

Replacing sensing film by pillars leads to unusual mass loading when the resonance frequency of the pillars is close to resonance frequency of the device. Unusual mass loading characteristics at three resonance modes of the pillars.

SAW sensors are MEMS devices which use modulation of surface acoustic waves to sense mass loading, small size, low power. Applications in resonators, sensors, actuators & signal processing.

Conventional SAW sensor

Research and Societal OutreachEco-friendly Development in Himalayan

HillsDeforestatio

n

Soil erosion

Flood

Slope Stability

Sarma B, Sarma A.K. and Singh V.P(2013):OPTIMAL ECOLOGICAL MANAGEMENT PRACTICES (EMPs) FOR MINIMIZING THE IMPACT OF CLIMATE CHANGE AND WATERSHED DEGRADATION DUE TO URBANIZATION , Water Resources Management, 27, 4069-4082, 2013.

• Center of Excellence – Department of Civil Engineering

• Integrated Land use Planning and Water Resources Management

• For hazard free development in hills – Technology for improving population carrying

capacity• Optimal Ecological Management Practices

(EMPs) has been developed to enhance hazard free carrying capacity– Single ownership: OPTEMP-LS – Multiple ownership:OPTEMP-LM

• Pilot project implementation in collaboration with government depts. and people has started

Research and Societal OutreachAssessing & Alleviating Adverse Impacts of

Climate Change on Brahmaputra Basin

Kalita H.M., Sarma A.K., and Bhattacharjya R.K, Evaluation of Optimal River Training Work using GA Based Linked Simulation Optimization Approach, Water Resource Management, 28, 2077-2098, 2014

• Managing dynamic river like Brahmaputra under climate change impacted water scenario is extremely challenging– Temp increase by 0.5 to 1.0

degree – Precipitation increase up to 20%– Shifting of Monsoon

• Homogeneous clustering to reduce uncertainty in Climate Change Prediction

• Indigenous River Model BRAHMA (Braided River Aid: Hydrodynamic and Morphological Analyzer) is developed and applied with Optimization Module

Indian Institute of Technology GuwahatiAmong

World's Top 100 Young Universities

• New Delhi, May 1, 2014– IIT Guwahati has shown the way to the new siblings

• The young IIT from Assam has brought cheer to Indian academic institutions – Occupying a place among the top 100 YOUNG universities

published by London-based Times Higher Education (THE) magazine• Young – under 50 years of age

– Placed 87th in the ranking that analysed 800 new-breed universities from 29 countries, including the US and the UK.

• The magazine has started a separate ranking for universities two years ago– For below 50 years of age– Suggest which institutions have the potential to become

the next generation’s Harvard or Oxford

Stratagem (Improvement of Rank)

•Research focus: Modern Manufacturing; Nanotechnology; Cancer Therapeutics; Creating new Fuels and Improved Energy Storage Systems; Improving Himalayan Habitat; Control of Flood and Land Erosion; Hydrology; Road and Infrastructure; etc.

•New-Pedagogy, such as, Flipped Learning and Education 3.0 have appeared in teaching strategies• Group work is an essential part of this new style of learning and classes have to be designed to engage students in group work as much as possible.

•The strategy ensures success of Outcome Based Learning:

•Graduates will demonstrate basic knowledge in mathematics, science • and engineering•Graduates will demonstrate the ability to design and conduct experiments, • interpret and analyze data, and report results

a) IIT Guwahati is the mentor Institute for IIIT Guwahati and IIIT Manipur

b) IIT Guwahati is helping NIT Meghalaya and NIT Sikkim on several academic aspects of institute-building

c) IIT Guwahati is associated with IIM Shillong

d) IIT Guwahati is the mentor Institute for CIT Kokrajhar

e) IIT Guwahati (RuTAG) has successfully set up a pilot project on production of Muga Silk fabric with power loom at the Export Promotion Industrial Park (EPIP) , Guwahati.  Muga Silk is one of the costliest fabrics in the world obtained from Antheraea Assamensis.

f) IIT Guwahati (RuTAG) has developed a low cost machine for production of compressed feed block fortified with micro nutrients to supplement the feed for Yaks and Mithuns (only available in Arunachal, Nagaland and Manipur)

g) Construction of Flyovers and laying Rail Track in N-E states

h) IITG is eager to start special MS program for the College Teachers of North East

Community Outreach

Water-polo Match at IIT Guwahati

Basketball Match at IIT Guwahati

Education is the manifestationof perfection already in man and characteris the test of thatmanifestation