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I. MitosisHappy Halloween!
Why do animals shed their skin?
A. Asexual Reproduction
1. When do cells use it?
a) ____________b) ____________c) ____________
2. Cell that reproduce by asexual reproduction reproduce constantly.
B. Mitosis = Asexual Reproduction
1. Division of ____________ __________(body)2. Process in which the nucleusdivides to form 2 new nuclei
Somatic Cell
Daughter Cells
Performed by a single (parent) cell
C. PURPOSE OF MITOSIS:
a. ____________ ____________
. . . OF CHROMOSOMESAS THE PARENT CELL.
b. ____________ ____________ ___
1. TO PRODUCE TWO NEW NUCLEI WITH…
D. What are Chromosomes?
1. ____________ structure of DNA in the cell
2. Located in the ____________ 3. Usually are uncoiled in the form of
____________ 4. Only ____________ when the cell
divides and the chromatin condenses5. Held together by a ____________
E. 5 Stages(do not write)
InterphaseProphaseMetaphaseAnaphaseTelophase
**Animated Video**
1. Interphase• Prior & After Mitosis• ____________ ____________ – ____________ % of cell life spent
here– Cell goes about it’s business
• ____________ ____________ – DNA is duplicated
• ____________ ____________ – Cell prepares to divide
• Cannot see DNA- uncoiled as ____________
2. Prophase
• DNA becomes ____________ as ____________ • Nuclear membrane ____________ • ____________ migrate to opposite
poles• Spindle fibers ____________
Easy to remember- Prophase- prepares for mitosis
3. Metaphase
• Spindle fibers ____________ to centromeres• Chromosomes ____________
at midline of the cell
Easy to remember- metaphase, DNA at middle
4. Anaphase
• Spindle fibers ____________ centromeres• One chromatid goes to each
____________ (they look like V’s)
Easy to remember- anaphase, away they go
5. Telophase
• Chromatids reach ____________ • Mitosis ends when new
____________ ____________ form• Some evidence of cell dividing
Easy to remember- telophase, terminal phase
6. Last part- Cytokinesis• Division of ____________ • Technically not in mitosis–Animal cell- pinching of cell membrane- cleavage–Plant cell- formation of new cell wall- cell plate–DNA becomes non-visible, back to chromatin
• Daughter cells enter G1 period of interphase
What Kind of Cells Does Mitosis Produce?
• Cells with a complete set of chromosomes called diploids
• Humans have 46 chromosomes or 23 pairs of chromosomes
• Human diploid # = 23• Most cells are diploid
Cancer
• Uncontrollable mitosis (no G1)– Cells cease to do what
they are supposed to be doing in favor of dividing.
• Cancer does not “poison” your body…
Henrietta Lacks• 1951, a poor 31 Year old African
American mother of 4 was dying of cervical cancer @ Johns Hopkins Hospital– Dr. George Gey- sampled some of the
cancerous cells, found they could live indefinitely and multiply outside the body
– She died 6 months later, but cells still live on
• HeLa cells– Used to study many different diseases– Polio Vaccine– How to transport cells
The Mitosis Shuffle!
• First, lets watch:University of Madison Mitosis Shuffle
• Your turn!“The Hustle” by Van McCoy