IEEE Catalog Number: ISBN:

CFP08837-PRT 978-1-4244-2878-6

2008 IEEE Biomedical Circuits and Systems Conference – Intelligent Biomedical Systems (BioCAS)

Baltimore, MD, USA 20-22 November 2008

Table of Contents

Thursday, November 20, 2008

A5P-B Biomedical Instrumentation and BioAnalysis Time: Thursday, November 20, 2008, 5:45 - 7:30PM Place: Peale Room Chair(s): Shantanu Chakrabartty, Michigan State University Ralph Etienne-Cummings, Johns Hopkins University A5P-B.1 Power Model for Wireless Body Area Network ............................................................................................ 1

ShihHeng Cheng, National Chiao Tung University ChingYao Huang, National Chiao Tung University

A5P-B.2 Spectral Analysis of Sustained Pupil Light Response to Short and Long Wavelength Light ................. 5

Wioletta Nowak, Wroclaw University of Technology / CRADLE Minoru Nakayama, Wroclaw University of Technology / CRADLE Hitoshi Ishikawa, Kitasato University Ken Asakawa, Kitasato University

A5P-B.3 A Distributed I/O Low-Level Controller for Highly-Dexterous Snake Robots ........................................... 9

Paul Thienphrapa, Johns Hopkins University Peter Kazanzides, Johns Hopkins University

A5P-B.4 An Efficient Synchronization Scheme for Digital UWB Communication Systems for

Biomedical Applications ............................................................................................................................... 13 Muhammad Cassim Munshi, National University of Singapore Jinhua Jiang, National University of Singapore Yan Xin, National University of Singapore Tor Sverre Lande, University of Oslo Yong Lian, National University of Singapore

A5P-B.5 Frequency Controllable in vivo Biological Oscillators .............................................................................. 17

Nathan Neihart, Iowa State University Brandi House, University of Washington

A5P-B.6 Real-Time Filtering Technique to Remove ECG Interference from Recorded

Esophageal EMG ........................................................................................................................................... 21 Bassam Rhou, École Polytechnique de Montréal Mohamad Sawan, École Polytechnique de Montréal Tommy Désilets, École Polytechnique de Montréal François Bellemare, CHUM-Hôtel-Dieu

A5P-B.7 Feature Extraction using an AM-FM Model for Gait Pattern Classification .......................................... 25

Ning Wang, University of New South Wales Eliathamby Ambikairajah, University of New South Wales Branko G. Celler, University of New South Wales Nigel H. Lovell, University of New South Wales

A5P-B.8 Modified Spectral Subtraction for De-Noising Heart Sounds: Interference Suppression via Spectral Comparison .................................................................................................................................... 29 Thanut Tosanguan, Imperial College London Robert J. Dickinson, Imperial College London Emmanuel M. Drakakis, Imperial College London

A5P-B.9 Practical Considerations for the use of a Howland Current Source for Neuro-Stimulation ................. 33

Philippe Pouliquen, Johns Hopkins University Jacob Vogelstein, Johns Hopkins University Ralph Etienne-Cummings, Johns Hopkins University

A5P-B.10 NeuralWISP: An Energy-Harvesting Wireless Neural Interface with 1-M Range ................................... 37

Jeremy Holleman, University of Washington Dan Yeager, University of Washington Richa Prasad, University of Washington Joshua R. Smith, Intel Research Seattle Brian Otis, University of Washington

A5P-B.11 Force Prediction and Tracking for Image-Guided Robotic System using Neural

Network Approach ......................................................................................................................................... 41 Ivan Buzurovic, Thomas Jefferson University Tarun K. Podder, Thomas Jefferson University Yan Yu, Thomas Jefferson University

A5P-B.12 Formant Map Counterpart in Auditory Processing based on Cochlear Pressure

Wave Trajectories .......................................................................................................................................... 45 Tamás Harczos, Fraunhofer IDMT Stephan Werner, Technical University Ilmenau Gero Szepannek, University Dortmund

A5P-B.13 Wireless Multichannel Acquisition of Neuropotentials ............................................................................ 49

Mohsen Mollazadeh, Johns Hopkins University Kartikeya Murari, Johns Hopkins University Helen Schwerdt, Johns Hopkins University Xing Wang, Johns Hopkins University Nitish Thakor, Johns Hopkins University Gert Cauwenberghs, University of California, San Diego

A5P-B.14 Towards Systematic Exploration of Tradeoffs for Medical Image Registration on

Heterogeneous Platforms ............................................................................................................................ 53 William Plishker, University of Maryland Omkar Dandekar, University of Maryland Shuvra S. Bhattacharyya, University of Maryland Raj Shekhar, University of Maryland

A5P-B.15 A Robotic Biarticulate Leg Model ............................................................................................................... 57

M. Anthony Lewis, University of Arizona Thresa J. Klein, University of Arizona

A5P-B.16 A Modified H.264 Intra-Frame Video Encoder for Capsule Endoscope .................................................. 61

Lan-Rong Dung, National Chiao Tung University Yin-Yi Wu, National Chiao Tung University Hsin-Cheng Lai, National Chiao Tung University Ping-Kuo Weng, Chung-shan Institute of Science and Technology

A5P-B.17 FPGA Implementation of 4-Channel ICA for On-Line EEG Signal Separation ........................................ 65 Wei-Chung Huang, National Chiao Tung University Shao-Hang Hung, National Chiao Tung University Jen-Feng Chung, National Chiao Tung University Meng-Hsiu Chang, National Chiao Tung University Lan-Da Van, National Chiao Tung University Chin-Teng Lin, National Chiao Tung University

Friday, November 21, 2008

B1L-A Bioelectronics and Biomedical Instrumentation Time: Friday, November 21, 2008, 8:15 - 10:00AM Place: Johnson Room Chair(s): Khaled Salama, Rensselaer Polytechnique Institute Raj Shekhar, University of Maryland

8:15 B1L-A.1 Quantitative Biomechanical Analysis of Drosophila Embryos through the Stages of

Embryogenesis using a Sensorized Human/Robot Cooperative Interface ............................................ 69 Scott J. Cozen, University of Nevada-Reno Rui Zhang, Michigan State University Yantao Shen, University of Nevada-Reno Ning Xi, Michigan State University Jingang Yi, State University of New Jersey

8:32 B1L-A.2 Readout Circuit Design for an EISCAP Biosensor ..................................................................................... 73

Hareesh Vemulachedu, Indian Institute of Technology Madras Shanthi Pavan, Indian Institute of Technology Madras Enakshi Bhattacharya, Indian Institute of Technology Madras

8:50 B1L-A.3 Design and Development of an active Laplacian Sensor for Non-Invasive Recordings of the

Intestinal Bioelectrical Signal ..................................................................................................................... 77 G. Prats-Boluda, Univesidad Politécnica de Valencia J. Garcia-Casado, Univesidad Politécnica de Valencia J.L. Martinez-De-Juan, Univesidad Politécnica de Valencia Y. Ye, Univesidad Politécnica de Valencia

9:07 B1L-A.4 A Novel Analogue Circuit for Controlling Prosthetic Hands ..................................................................... 81

Eduardo Mangieri, University of Southampton Arash Ahmadi, University of Southampton Koushik Maharatna, University of Southampton Siti A. Ahmad, University of Southampton Paul H. Chappell, University of Southampton

9:25 B1L-A.5 A Portable SoC-based ECG-System for 24h x 7d Operating Time ........................................................... 85

Wjatscheslaw Galjan, Hamburg University of Technology Desislava Naydenova, Hamburg University of Technology Jakob M. Tomasik, Hamburg University of Technology Dietmar Schroeder, Hamburg University of Technology Wolfgang H. Krautschneider, Hamburg University of Technology

9:42 B1L-A.6 Voltage Sensitive Dye Imaging System for Awake and Freely Moving Animals .................................... 89

Joon Hyuk Park, Yale University Eugenio Culurciello, Yale University Dongsoo Kim, Yale University Justus Velentijn Verhagen, Yale University Shree Hari Gautam, Yale University Vincent Pieribone, Yale University

B2L-A Implantable and Wearable Electronics Time: Friday, November 21, 2008, 10:15 - 12:00PM Place: Johnson Room Chair(s): Maysam Ghovanloo, Georgia Institute of Technology Mohamed Sawan, University of Wisconsin-Madison

10:15 B2L-A.1 A Fully Integrated DPSK Demodulator for High Density Biomedical Implants ...................................... 93

Jungsuk Kim, University of California, Santa Cruz Moo Sung Chae, University of California, Santa Cruz Lihsien Wu, University of California, Santa Cruz Wentai Liu, University of California, Santa Cruz

10:32 B2L-A.2 Optimization of a Multiband Wireless Link for Neuroprosthetic Implantable Devices ......................... 97

Uei-Ming Jow, Georgia Institute of Technology Maysam Ghovanloo, Georgia Institute of Technology

10:50 B2L-A.3 An Efficient Wireless Power Link for High Voltage Retinal Implant .................................................... 101

Lihsien Wu, University of California, Santa Cruz Zhi Yang, University of California, Santa Cruz Eric Basham, University of California, Santa Cruz Wentai Liu, University of California, Santa Cruz

11:07 B2L-A.4 Fully-Integrated Inductive Power Recovery Front-End Dedicated to Implantable Devices .............. 105

Fayçal Mounaim, Polystim Neurotechnologies Laboratory Mohamad Sawan, Polystim Neurotechnologies Laboratory Mourad El-Gamal, McGill University

11:25 B2L-A.5 Orthogonally Oriented Coils for Minimization of Cross-Coupling in Cortical Implants ...................... 109

Kanber Mithat Silay, Ecole Polytechnique Fédérale de Lausanne Catherine Dehollain, Ecole Polytechnique Fédérale de Lausanne Michel Declercq, Ecole Polytechnique Fédérale de Lausanne

11:42 B2L-A.6 Experimental Thermal Study of a TET System for Implantable Biomedical Devices ......................... 113

Thushari D. Dissanayake, University of Auckland David Budgett, University of Auckland Patrick Hu, University of Auckland Simon Malpas, University of Auckland

B3L-A SPECIAL SESSION: Revolutionizing Prosthetics Time: Friday, November 21, 2008, 2:00 - 3:35PM Place: Johnson Room Chair(s): Reid Harrison, University of Utah Jacob Vogelstein, Johns Hopkins University Applied Physics Laboratory

14:00 B3L-A.1 IMES - Implantable MyoElectric Sensor System: Designing Standardized ASICs .............................. 117

Glenn A. Demichele, Sigenics, Inc. Philip R. Troyk, Sigenics, Inc. Douglas Kerns, Sigenics, Inc. Richard F. Ff. Weir, Rehabilitation Institute of Chicago

14:17 B3L-A.2 Air-Guitar Hero: A Real-Time Video Game Interface for Training and Evaluation of Dexterous

Upper-Extremity Neuroprosthetic Control Algorithms ........................................................................... 121 Robert S. Armiger, Johns Hopkins University R. Jacob Vogelstein, Johns Hopkins University

14:35 B3L-A.3 A Wireless Neural Interface for Chronic Recording ............................................................................... 125

Reid R. Harrison, University of Utah Ryan J. Kier, University of Utah Sohee Kim, University of Utah Loren Rieth, University of Utah David J. Warren, University of Utah Noah M. Ledbetter, University of Utah Gregory A. Clark, University of Utah Florian Solzbacher, University of Utah Cynthia A. Chestek, Stanford University Vikash Gilja, Stanford University Paul Nuyujukian, Stanford University Stephen I. Ryu, Stanford University Krishna V. Shenoy, Stanford University

14:52 B3L-A.4 Wireless Integrated Circuit for 100-Channel Neural Stimulation ........................................................ 129

Brandon K. Thurgood, University of Utah Noah M. Ledbetter, University of Utah David J. Warren, University of Utah Gregory A. Clark, University of Utah Reid R. Harrison, University of Utah

15:10 B3L-A.5 An Efficient Approximation for the Real-Time Implementation of the Mixture of Trajectory

Models Decoder .......................................................................................................................................... 133 William Bishop, Johns Hopkins University Byron M. Yu, Stanford University Gopal Santhanam, Stanford University Afsheen Afshar, Stanford University Stephen I. Ryu, Stanford University Krishna V. Shenoy, Stanford University

15:27 B3L-A.6 Conveying Tactile Feedback using a Model of Mechanotransduction ................................................ 137

Sliman Bensmaia, Johns Hopkins University Sung Soo Kim, Johns Hopkins University Arun Sripati, Carnegie Mellon University R. Jacob Vogelstein, Johns Hopkins University

B4L-A SPECIAL SESSION: Smart Sensors, Intelligent and Reconfigurable Systems for Biomedical Applications

Time: Friday, November 21, 2008, 4:00 - 5:45PM Place: Johnson Room Chair(s): Abbes Amira, Brunel University Farid Boussaid, University of Western Australia

16:00 B4L-A.1 Towards an Optimized Design for Tetrapolar Affinity-based Impedimetric Immunosensors

for Lab-on-a-Chip Applications .................................................................................................................. 141 Panagiotis Kassanos, University College London Andreas Demosthenous, University College London Richard H. Bayford, Middlesex University

16:17 B4L-A.2 A CMOS Digital Pixel Sensor with Photo-Patterned Micropolarizer Array for Real-Time

Focal-Plane Polarization Imaging ............................................................................................................ 145 Xiaojin Zhao, Hong Kong University of Science and Technology Amine Bermak, Hong Kong University of Science and Technology Farid Boussaid, University of Western Australia

16:35 B4L-A.3 Intelligent Systems for the Prediction of Brain Death Index ................................................................ 149

M.F. Abbod, Brunel University J. Shieh, Yuan-Ze University J. Yeh, Yuan-Ze University K. Cheng, Yuan-Ze University S.J. Huang, National Taiwan University Hospital Y.Y. Han, National Taiwan University Hospital

16:52 B4L-A.4 Analogue VLSI Implementations of Two Dimensional, Nonlinear, Active Cochlea Models .............. 153

Tara Julia Hamilton, University of Queensland Jonathan Tapson, University of Cape Town Craig Jin, University of Sydney André van Schaik, University of Sydney

17:10 B4L-A.5 An Efficient Algorithm and Architecture for Medical Image Segmentation and

Tumour Detection ....................................................................................................................................... 157 Mhd S. Sharif, Brunel University Abdul N. Sazish, Brunel University Abbes Amira, Brunel University

17:27 B4L-A.6 Improved Dynamic Shape Representation using a Biologically-Inspired Vision Sensor with a

Synchronous Arbitration ............................................................................................................................ 161 A.N. Belbachir, Austrian Research Centers GmbH - ARC M. Hofstätter, Austrian Research Centers GmbH - ARC M. Litzenberger, Austrian Research Centers GmbH - ARC P. Schön, Austrian Research Centers GmbH - ARC

B5P-B Electronic Circuits for Bioapplications and BioModels Time: Friday, November 21, 2008, 5:45 - 7:30PM Place: Peale Room Chair(s): Julio Georgiou, University of Cyprus Sylvie Renaud, Université Bordeaux B5P-B.1 A Low-Noise CMOS Receiver Frontend for MRI ...................................................................................... 165

Jens Anders, Ecole Polytechnique Fédérale de Lausanne Giovanni Boero, Ecole Polytechnique Fédérale de Lausanne

B5P-B.2 Analog to Interval Encoder with Active use of Gate Leakage for an Implanted Blood-Sugar Sensor .................................................................................................................................... 169 P. Häfliger, University of Oslo E. Johannessen, Lifecare AS

B5P-B.3 Parameter Estimation of the Hodgkin–Huxley Model using Metaheuristics: Application to

Neuromimetic Analog Integrated Circuits .............................................................................................. 173 L. Buhry, University of Bordeaux S. Saïghi, University of Bordeaux A. Giremus, University of Bordeaux E. Grivel, University of Bordeaux S. Renaud, University of Bordeaux

B5P-B.4 An UWB System for Wireless Endoscope ................................................................................................ 177

Chul Kim, University of New South Wales Saeid Nooshabadi, Gwangju Institute of Science and Technology Torsten Lehmann, University of New South Wales

B5P-B.5 Real-Time Silicon Implementation of V1 in Hierarchical Visual Information Processing ................. 181

Fopefolu Folowosele, Johns Hopkins University R. Jacob Vogelstein, Johns Hopkins University Ralph Etienne-Cummings, Johns Hopkins University

B5P-B.6 Design of an Integrated Sensor for Noninvasive Optical Mammography based on

Frequency-Domain NIR Spectroscopy ..................................................................................................... 185 Ruida Yun, Tufts University Valencia M. Joyner, Tufts University

B5P-B.7 Analog Logic Automata ............................................................................................................................. 189

Kailiang Chen, MIT Jonathan Leu, MIT Neil Gershenfeld, MIT

B5P-B.8 An Interference-Resilient Body Channel Transceiver for Wearable Body Sensor Network .............. 193

Namjun Cho, Korea Advanced Institute of Science and Technology Joonsung Bae, Korea Advanced Institute of Science and Technology Hoi-Jun Yoo, Korea Advanced Institute of Science and Technology

B5P-B.9 A Micropower Tilt Processing Circuit ...................................................................................................... 197

Timothy G. Constandinou, Imperial College London Julius Georgiou, University of Cyprus

B5P-B.10 Computing Lightness Constancy with an APS-based Silicon Retina ................................................... 201

Kazuhiro Shimonomura, Osaka University Tetsuya Yagi, Osaka University

B5P-B.11 Low-Threshold Voltage Multipliers based on Floating-Gate Charge-Pumps ....................................... 205

Chenling Huang, Michigan State University Shantanu Chakrabartty, Michigan State University

B5P-B.12 Adaptive Detection of Action Potentials using Ultra Low-Power CMOS Circuits ............................... 209

Benoit Gosselin, École Polytechnique de Montréal Mohamad Sawan, École Polytechnique de Montréal

B5P-B.13 A CMOS Integrated Bacterial Sensor for Rapid Detection of Pseudomonas Aeruginosa ................. 213

N. Nikkhoo, University of Toronto C. Mann, University of Toronto P.G. Gulak, University of Toronto K. Maxwell, University of Toronto

B5P-B.14 Integrated CMOS Imager for Pattern Recognition ................................................................................ 217 Anshu Sarje, University of Maryland Sharad Satsangi, University of Maryland Armstard C. Skipwith, University of Maryland Jui-Ping Chiang, University of Maryland Pamela Abshire, University of Maryland

B5P-B.15 A 94-µW 10-b Neural Recording Front-End for an Implantable Brain-Machine-Brain

Interface Device ......................................................................................................................................... 221 Meysam Azin, Case Western Reserve University Pedram Mohseni, Case Western Reserve University

B5P-C SPECIAL SESSION: PhD in a Nutshell Time: Friday, November 21, 2008, 5:45 - 7:30PM Place: Peale Room Chair(s): Mohsen Mollazadeh, Johns Hopkins University Kartikeya Murari, Johns Hopkins University B5P-C.1 Spike-based Acoustic Signal Processing Chips for Detection and Localization ................................ 225

Hisham Abdalla, University of Maryland Timothy K. Horiuchi, University of Maryland

B5P-C.2 Chemical Bionics - A Novel Design Approach using Ion Sensitive Field Effect Transistors .............. 229

Pantelis Georgiou, Imperial College London Chris Toumazou, Imperial College London

B5P-C.3 Development of Novel SAW Devices in CMOS Technology for Biosensor Applications .................... 233

Onur Tigli, George Washington University Mona E. Zaghloul, George Washington University

B5P-C.4 Reverse Engineering the Principal Image Processing Architectures of the Macula Lutea

within the Human Retina ........................................................................................................................... 237 Dylan Banks, Imperial College London Chris Toumazou, Imperial College London

B5P-C.5 Biomorphic Circuits and Systems: Control of Robotic and Prosthetic Limbs ..................................... 241

Francesco Tenore, Johns Hopkins University Ralph Etienne-Cummings, Johns Hopkins University

B5P-C.6 High Resolution Imaging through Integrated Nanoholes Image Sensor ............................................. 245

Tamer E. Elkhatib, Rensselaer Polytechnic Institute Khaled N. Salama, Rensselaer Polytechnic Institute

B5P-C.7 Forward Error Correcting Biosensors: Modeling, Algorithms and Fabrication ................................... 249

Yang Liu, Michigan State University Evangelyn Alocilja, Michigan State University Shantanu Chakrabartty, Michigan State University

Saturday, November 22, 2008

C1L-A Brain Science Electronics Time: Saturday, November 22, 2008, 8:15 - 10:00AM Place: Johnson Room Chair(s): Timothy Constandinou, Imperial College Nitish Thakor, John Hopkins University

8:15 C1L-A.1 Fast Stimulus Artifact Recovery in a Multichannel Neural Recording System .................................. 253

Matthew C. Schoenecker, University of California, San Francisco Ben H. Bonham, University of California, San Francisco

8:32 C1L-A.2 A Low-Power Integrated Circuit for Analog Spike Detection and Sorting in Neural

Prosthesis Systems .................................................................................................................................... 257 A. Bonfanti, Politecnico di Milano - IU. NET T. Borghi, Politecnico di Milano - IU. NET R. Gusmeroli, Politecnico di Milano - IU. NET G. Zambra, Politecnico di Milano - IU. NET A. Oliynyk, Università degli Studi di Ferrara L. Fadiga, Università degli Studi di Ferrara A.S. Spinelli, Politecnico di Milano - IU. NET G. Baranauskas, Italian Institute of Technology

8:50 C1L-A.3 Towards the Development of Phased Array Systems for Deep Brain Stimulation ............................. 261

Virgilio Valente, University College London Andreas Demosthenous, University College London Richard Bayford, Middlesex University

9:07 C1L-A.4 VLSI-Friendly Algorithm for Real-Time Spike Sorting in Brain Machine

Interface Applications ............................................................................................................................... 265 Faisal T. Abu-Nimeh, Michigan State University Mehdi Aghagolzadeh, Michigan State University Karim G. Oweiss, Michigan State University

9:25 C1L-A.5 An Implantable CMOS Image Sensor for Monitoring Deep Brain Activities of a Freely

Moving Mouse ............................................................................................................................................ 269 Jun Ohta, Nara Institute of Science and Technology Asako Higuchi, Nara Institute of Science and Technology Ayato Tagawa, Nara Institute of Science and Technology Kiyotaka Sasagawa, Nara Institute of Science and Technology Takashi Tokuda, Nara Institute of Science and Technology Yumiko Hatanaka, Nara Institute of Science and Technology Hideki Tamura, Nara Institute of Science and Technology Sadao Shiosaka, Nara Institute of Science and Technology

9:42 C1L-A.6 A Mobile EEG System with Dry Electrodes .............................................................................................. 273

Gaetano Gargiulo, University of Sydney Paolo Bifulco, Università degli Studi di Napoli Federico II Rafael A. Calvo, University of Sydney Mario Cesarelli, Università degli Studi di Napoli Federico II Craig Jin, University of Sydney André van Schaik, University of Sydney

C2L-A Neuromorphic Engineering Time: Saturday, November 22, 2008, 10:15 - 12:00PM Place: Johnson Room Chair(s): Philipp Hafliger, University of Oslo Tor Sverre Lande, University of Oslo

10:15 C2L-A.1 Mismatch Reduction with Relative Reset in Integrate-and-Fire Photo-Pixel Array ........................... 277

J.A.M. Olsson, University of Oslo P. Häfliger, University of Oslo

10:32 C2L-A.2 An Analog Bionic Vocal Tract .................................................................................................................... 281

Keng Hoong Wee, MIT Lorenzo Turicchia, MIT Rahul Sarpeshkar, MIT

10:50 C2L-A.3 A Size and Position Invariant Event-based Human Posture Recognition Algorithm .......................... 285

Shoushun Chen, Yale University Fopefolu Folowosele, Johns Hopkins University Dongsoo Kim, Yale University R. Jacob Vogelstein, Johns Hopkins University Ralph Etienne-Cummings, Johns Hopkins University Eugenio Culurciello, Yale University

11:07 C2L-A.4 Dynamical Digital Silicon Neurons ........................................................................................................... 289

Andrew Cassidy, Johns Hopkins University Andreas G. Andreou, Johns Hopkins University

11:25 C2L-A.5 A Reconfigurable, Analog System for Efficient Stochastic Biological Computation ......................... 293

Bo Marr, Georgia Institute of Technology Stephen Brink, Georgia Institute of Technology Paul Hasler, Georgia Institute of Technology David V. Anderson, Georgia Institute of Technology

11:42 C2L-A.6 Neuromorphic Interconnects using Ultra Wideband Radio .................................................................. 297

Andrew Cassidy, Johns Hopkins University Zhaonian Zhang, Johns Hopkins University Andreas G. Andreou, Johns Hopkins University

C3L-A Lab-on-Chip and Bio-Nanotechnology Time: Saturday, November 22, 2008, 2:00 - 3:35PM Place: Johnson Room Chair(s): Eugenio Culurciello, Yale University William Plishker, University of Maryland

14:00 C3L-A.1 Automated, Accurate, and Inexpensive Solution-Preparation on a Digital

Microfluidic Biochip ................................................................................................................................... 301 Tao Xu, Duke University Vamsee K. Pamula, Advanced Liquid Logic, Inc Krishnendu Chakrabarty, Duke University

14:17 C3L-A.2 Chemical Stimulation of Aplysia Californica Ganglion with Microfluidic Signal Generators ........... 305

Farouk Azizi, University of Utah Carlos H. Mastrangelo, University of Utah Hui Lu, Case Western Reserve Univesrity Hillel J. Chiel, Case Western Reserve University

14:35 C3L-A.3 Teflon-Seated One-Lambda Microvalves for PDMS Chips ..................................................................... 309

Y. Xie, University of Utah Y. Wang, University of Utah F. Azizi, University of Utah C.H. Mastrangelo, University of Utah

14:52 C3L-A.4 High-Integrated Microvalve for Lab-on-Chip Biomedical Applications ................................................ 313

Miguel Moreno, University of Seville Carmen Aracil, University of Seville José M. Quero, University of Seville

15:10 C3L-A.5 Comparison of Tetrapolar Injection-Measurement Techniques for Coplanar Affinity-based

Impedimetric Immunosensors .................................................................................................................. 317 Panagiotis Kassanos, University College London Andreas Demosthenous, University College London Richard H. Bayford, Middlesex University

15:27 C3L-A.6 Batch Encapsulation Technique for CMOS based Chemical Sensors ................................................. 321

T. Prodromakis, Imperial College London P. Georgiou, Imperial College London T.G. Constandinou, Imperial College London K. Michelakis, Imperial College London C. Toumazou, Imperial College London

C4L-A SPECIAL SESSION: Nano-electronics and Nano-sensors for Medical Diagnostics Time: Saturday, November 22, 2008, 4:00 - 5:45PM Place: Johnson Room Chair(s): Sandro Carrara, EPFL Lausanne

16:00 C4L-A.1 Circuits Design and Nano-Structured Electrodes for Drugs Monitoring in

Personalized Therapy ................................................................................................................................. 325 Sandro Carrara, Ecole Polytechnique Fédérale de Lausanne Andrea Cavallini, Ecole Polytechnique Fédérale de Lausanne Giovanni De Micheli, Ecole Polytechnique Fédérale de Lausanne Jacopo Olivo, Bologna University Luca Benini, Bologna University Victoria V. Shumyantseva, Russian Academy of Biomedical Science, Moscow Alexander I. Archakov, Russian Academy of Biomedical Science, Moscow

16:17 C4L-A.2 Towards Fault-Tolerant Digital Microfluidic Lab-on-Chip: Defects, Fault Modeling, Testing,

and Reconfiguration .................................................................................................................................. 329 Krishnendu Chakrabarty, Duke University

16:35 C4L-A.3 Ultra Low Power Signal Processing Architectures ................................................................................. 333

Vinay Saripalli, Pennsylvania State Univeristy Saurabh Mookerjea, Pennsylvania State University Suman Datta, Pennsylvania State University Narayanan Vijaykrishnan, Pennsylvania State University

16:52 C4L-A.4 A Hybrid Microfluidic System for Cancer Diagnosis based on MEMS Biosensors ............................. 337

Pedro Ortiz, Newcastle University Neil Keegan, Newcastle University Julia Spoors, Newcastle University John Hedley, Newcastle University Alun Harris, Newcastle University Jim Burdess, Newcastle University Richard Burnett, Newcastle University Thomas Velten, Fraunhofer Institute for Biomedical Engineering IBMT Margit Biehl, Fraunhofer Institute for Biomedical Engineering IBMT Thorsten Knoll, Fraunhofer Institute for Biomedical Engineering IBMT Werner Haberer, Fraunhofer Institute for Biomedical Engineering IBMT Matthew Solomon, MiniFAB Andrew Campitelli, MiniFAB Calum McNeil, Newcastle University

17:10 C4L-A.5 Nanoscale Design of Ultrastrong Materials by LBL Assembly .............................................................. 341

Paul Podsiadlo, University of Michigan Nicholas A. Kotov, University of Michigan

17:27 C4L-A.6 Optical MEMS and Nano-Photonics for Diagnostics .............................................................................. 345

Aaron T. Ohta, University of California, Berkeley Hsan-Yin Hsu, University of California, Berkeley Arash Jamshidi, University of California, Berkeley Ming C. Wu, University of California, Berkeley

C5P-B Biomedical Technology and Sensor Systems Time: Saturday, November 22, 2008, 5:45 - 7:30PM Place: Peale Room Chair(s): Julio Georgiou, University of Cyprus Philipp Hafliger, University of Oslo C5P-B.1 Feature Extraction of Knee Joint Sound for Non-Invasive Diagnosis of Articular Pathology ............ 349

Keo-Sik Kim, Chonbuk National University Chul-Gyu Song, Chonbuk National University Jeong-Hwan Seo, Chonbuk National University

C5P-B.2 Influence of a Loose-Fitting Sensing Garment on Posture Recognition in Rehabilitation ............... 353

Holger Harms, ETH Zurich Oliver Amft, ETH Zurich Gerhard Tröster, ETH Zurich

C5P-B.3 Estimation of Sleepiness using Frequency Components of Pupillary Response ............................... 357

Minoru Nakayama, Tokyo Institute of Technology / CRADLE Keiko Yamamoto, Aichi Medical University Fumio Kobayashi, Aichi Medical University

C5P-B.7 Measuring the Impedance of a Tethered Bilayer Membrane Biosensor ............................................. 361

Tara Julia Hamilton, University of Queensland André van Schaik, University of Sydney Bruce Cornell, Surgical Diagnostics Pty. Ltd.

C5P-B.8 Development of Portable Cystometry Device based on Hand-Held Mobile Computer ...................... 365 Chul-Gyu Song, Chonbuk National University Keo-Sik Kim, Chonbuk National University Yang-Su An, Chonbuk National University Jeong-Hwan Seo, Chonbuk National University

C5P-B.9 Comparison of Bio-Impedance Changes and EMG Activity During Daily Events ................................ 369

Chul-Gyu Song, Chonbuk National University Keo-Sik Kim, Chonbuk National University Yang-Su An, Chonbuk National University Jeong-Hwan Seo, Chonbuk National University

C5P-B.10 Hilbert-Huang Transform: Preliminary Studies in Epilepsy and Cardiac Arrhythmias ....................... 373

Amir Eftekhar, Imperial College London Farah Vohra, Imperial College London Chris Toumazou, Imperial College London Emmanuel M. Drakakis, Imperial College London Kim Parker, Imperial College London

C5P-B.11 Laser Diode used in 16 Mb/s, 10 mW Optical Transcutaneous Telemetry System ........................... 377

Stéfan Parmentier, Université de Sherbrooke Réjean Fontaine, Université de Sherbrooke Yves Roy, Victhom Human Bionics

C5P-B.12 The Feeling of Color: A Haptic Feedback Device for the Visually Disabled ........................................ 381

Jonathan Tapson, University of Cape Town Javier Diaz, Universidad de Granada David Sander, University of Maryland Netta Gurari, Johns Hopkins University Elisabetta Chicca, ETH Zurich Philippe Pouliquen, Johns Hopkins University Ralph Etienne-Cummings, Johns Hopkins University

C5P-B.15 Self-Powered CMOS Impact-Rate Monitors for Biomechanical Implants ........................................... 385

Chenling Huang, Michigan State University Shantanu Chakrabartty, Michigan State University

C5P-B.16 Pressure Detection and Wireless Interface for Patient Bed ................................................................. 389

Achutan Manohar, University of Texas at Dallas Dinesh Bhatia, University of Texas at Dallas

C5P-B.17 Improved Growing Rod for Early Onset Scoliosis ................................................................................... 393

Scott Decker, Johns Hopkins University Gabriel Kim, Johns Hopkins University Mark Kim, Johns Hopkins University Benjamin Lee, Johns Hopkins University

C5P-B.18 A Low Power CMOS Image Sensor Design for Wireless Endoscopy Capsule ..................................... 397

Milin Zhang, Hong Kong University of Science and Technology Amine Bermak, Hong Kong University of Science and Technology Xiaowen Li, Tsinghua University Zhihua Wang, Tsinghua University

Author Index