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Welcoming Remarks The Center for Laser Applications (CLA) at the University of Tennessee Space Institute is pleased to present an overview of the research projects funded by the Center and external sources for fiscal years 2008 through 2012.

Over the past year, The Center for Laser Applications supported the research efforts of eight UTSI Center-associated faculty who have made significant advancements in vision research, laser materials processing, chemical synthesis, single-molecule detection, nanotechnology, biotechnology, biomedical research, computational physics, plasma physics, laser-induced optical breakdown and fluid physics phenomena and electromagnetics. As a result of this research CLA faculty members were awarded four patents, three provisional patents, and have several additional patents pending.

Productivity among Center faculty has been outstanding over the past five years. Center faculty obtained $6,294,776 in industry and federal funding to continue ongoing projects and begin new ones. Research expenditures from this funding amounted to $6,402,456. The appropriations received from the Tennessee Higher Education Commission amounted to $4,526,732 during the same time period. CLA benefited not only from external funding and state appropriations, but also from the American Reinvestment and Recovery Act funds. In total, these funds pay for the general operations of the Center and the research conducted in CLA, including the Center support staff, laboratory supplies, maintenance, travel for faculty and students to conferences, and research experiences for summer interns. Capital equipment must also come from this budget. In the past five years we have been fortunate to obtain a class 1000 clean room with a femtosecond nanomaching station and photolithography capability, a revitalized chemistry laboratory with a secondary ion mass spectrometer, an optomec LENS machine for direct metal deposition, a modular fluorometer/phosphorimeter for fluorescence studies, a pulsed laser deposition system, and a JEOL 6320F field emission scanning electron microscope. With these capabilities CLA has been successful in the pursuit of new capabilities and new sources of funding.

In spite of difficult economic times our research expenditures have been maintained. We are enthusiastic about our opportunities for the future and proud of the past accomplishments and hope you enjoy the research summaries that follow in this five-year review.

William HofmeisterDirector, Center for Laser Applications

Research Professor of Materials Science and Engineering

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For more information Ph: 931-393-7466 or Fax: 931-393-7437

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Center for Laser ApplicationsAnnual Report 2011-2012

Table of ContentsProgram Report Introduction............................................................................4 Mission Statement..............................................................4 Focus Areas...........................................................................4 Personnel................................................................................6 Collaborations.......................................................................6 Graduate Student Support..............................................7 Post Doctoral Support......................................................7 Outreach and Enrichment Programs.........................8 Research Accomplishments and Five year Benchmark.........................................................9 Comparative Summary of Accomplishments.........9 Future Directions................................................................11 Center for Laser Applications Budget......................12

Faculty Reports Ying-Ling Chen.....................................................................13 José Lino Vasconcelos da Costa................................14 Lloyd Davis............................................................................15 William Hofmeister...........................................................16 Charles Johnson................................................................17 Jacqueline Johnson..........................................................18 Trevor Moeller.....................................................................19 George Murray.................................................................20 Christian Parigger............................................................21

Publications Awards..................................................................................22 Appointments.....................................................................22 Publications.........................................................................22 Conference Proceedings...............................................24 Presentations.....................................................................25 Patents..................................................................................30 Research Funded Externally.........................................31

This report is

published by

the University

of Tennessee

Center

for Laser

Applications

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Introduction The Center for Laser Applications (CLA) at the University of Tennessee Space Institute was established in 1984 as a state funded Center of Excellence to provide outstanding capabilities in research, education, and technology transfer in the area of laser applications. CLA began as an active multi-disciplined and collaborative research group at UTSI with expertise and significant industrial and university-based experience in phenomena related to the interactions of lasers with gases, liquids, and solids. The diverse background of the faculty and staff and the strong mission-related research programs of CLA provide a blend of applied and basic research that is unusual for universities.

Mission Statement The CLA mission is to advance laser applications in spectroscopy and materials synthesis. We pursue our mission in three areas:

1) Education - Provide a quality education to UTSI students with emphasis on apprenticeship - Generate opportunities for undergraduate and high school student research2) Innovation - Develop a world class reputation for research and innovation3) Service - Assist businesses in development and implementation of technology - Increase interest in STEM areas, i.e. support science education for local students and teachers

Focus Areas The focus of the mission-related research programs of the Center is the application of lasers and associated technology to bio/nanophotonics, materials science, laser materials interaction, and spectroscopy. These focus areas of specialization were selected to correspond to known areas of scientific and engineering challenges and to areas of development and regional and national needs.

Bio/Nanophotonics• Lloyd Davis - single molecule spectroscopy of biomolecules in confined spaces• Ying-Ling Chen - vision research and modeling of human vision systems• William Hofmeister and Lino Costa - devices for cellular chemotaxis• Jacqueline Johnson - storage phosphor materials for mammography• George Murray - colorimetric detection of bioactive molecules

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Materials Science

• George Murray - synthesis of molecularly imprinted polymers• William Hofmeister - solidification, direct metal deposition and femtosecond nano-

structuring of materials• Lino Costa - phase transformations, laser cladding and modeling of direct metal

deposition• Lloyd Davis - trapping and diagnostics of quantum dots • Christian Parigger - laser-induced materials physics• Jacqueline Johnson - development of glass imaging material

Laser Materials Interaction

• Lino Costa - laser cladding and femtosecond laser machining • William Hofmeister - direct metal deposition and femtosecond nanostructuring of materials• Trevor Moeller - laser ablation dynamics and modeling of laser ablation for space propulsion • Lloyd Davis - femtosecond fabrication of nanofluidic and wave guide devices

Spectroscopy • Charles Johnson - Mössbauer spectroscopy • Christian Parigger - ultrasensitive spectroscopy• Lloyd Davis - single molecule spectroscopy• Ying-Ling Chen - combustion diagnostics• George Murray - Raman and electrochemical spectroscopy

Non-Equilibrium Fluid Physics• Trevor Moeller - plasma physics and combustion• Christian Parigger - laser-plasma physics, combustion and fluid phenomena, and computational modeling

Finite Element Modeling

of Three Dimensional

Freeform Fabrication

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Personnel Dr. William Hofmeister, Research Professor of Materials Science and Engineering, was appointed Director of the Center in 2005. Dr. Hofmeister added two faculty members to the Center to support the goals set by the UTSI revitalization plan to develop a program

in Materials Science while maintaining the excellence in the forefront of spectroscopy and laser materials modification. In 2007 Dr. Jacqueline Johnson promptly secured a major grant from the National Institutes of Health for the development of materials for mammography. The following year Dr. George Murray joined CLA. Dr. Murray’s research in molecular recognition for biomedical applications secured grants from NSF, Raptor Detection and Ambiocore, Inc. Coupled with Dr. Hofmeister’s work in Freeform Fabrication, these projects represent a solid foundation for Materials Science at UTSI. Dr. Lloyd Davis’ research in single molecule

spectroscopy received a major boost with a DARPA grant in collaboration with Hofmeister and colleagues at Vanderbilt University, and an NIH grant with Dr. Steven Soper at LSU. Dr. Ying-Ling Chen’s work with eye modeling and diagnostics has been advanced with two grants from NIH and collaboration with Dr. Ming Wang of Wang Vision Institute. Dr. Trevor Moeller continues to serve the aerospace establishment with a number of grants and task orders with Arnold Engineering Development Center. Dr. Christian Parigger continues to collaborate on various experimental, theoretical and computational modeling and joint efforts with national and international Universities and National Laboratories in the areas of laser physics, laser applications and laser-induced phenomena.

Collaborations A significant fraction of the research and development program of the Center is supported by state, regional, and national industries. CLA actively collaborates with the Center for Industrial Services to provide studies for Tennessee industries, and CLA has also formed long-term research partnerships with regional and national industries. Supplementing these activities are research programs sponsored by the traditional federal agencies, the National Institutes of Health, the National Science Foundation, and National Laboratories at Oak Ridge and Albuquerque, over and above numerous collaborations with national and international Universities, and the nearby Arnold Engineering Development Center. These diverse research activities, an attractive student-to-faculty ratio, and outstanding facilities, combine to offer an unusual apprenticeship experience for diligent graduate students.

Dr. Murray checks the performance of molecular sequestration beads.

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Graduate Student Support Over the past five years CLA supported 37 graduate student degrees with a combination of external research funding, UTSI support, ARRA and THEC funds.

• Materials Science PhD: Sameer Paital, Anoop Samant, Sandip Harimkar and Greg Engleman MS: Anil Kumar Kurella, Matthew Parrish, Deepak Rajput, Russell Lee Leonard and Mahn Vu• Mechanical Engineering MS: Daniel Rooney, Sonya Nelson, Jeffrey King, Sarah Cothran, Densu Aktas, Nicholas Lister, Richard Joel Thompson, Kent Wilcher, Marcus Conner and Russell Gardner, and Nehemiah Williams• Electrical Engineering and Computer Science MS: Isaac Lescano-Mendoza • Physics PhD: Kevin Baker, David Ball, and Bo Tan MS: Karen Norton, Matt Dackman, James Aiken, Jesse Ogle, Lei Shi, James Guan, You Li, Jason King, Jesse Labello, Justin Crawford, James Germann, and William Robinson

Post Doctoral Support The Center supports post doctoral fellows for continuing education and research support. Currently, Dr. Brian Canfield is working in the Davis lab on single molecule spectroscopy. Mr. Robert Rhodes continues to support the nonequilibrium fluid physics research with Dr. Moeller. Dr. Abhilasha Verma is completing her first year working on molecular imprinting polymer for protein sequestration and Dr. George Owens recently joined Professor Murray’s group as a post doc. Last year Dr. José Lino Vasconcelos da Costa, a specialist

in laser processing, was promoted to Research Assistant Professor at UTSI. Past post doctoral fellows include: Dr. Paul Shen, Luna Innovations, Dr. Yelena White currently is an Assistant Professor of Physical Science for the Physics Department at East Georgia College. Dr. Zbigniew Sikorski remains active in the area of computational modeling and Dr. Xiaoxuan “Shaun” Li is a Materials Engineer at Secat, Inc. in Kentucky. Post Doc Brian Canfield

Post Doc Abhilasha Verma

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Outreach and Enrichment Programs CLA is dedicated to impacting our community in a positive way with meaningful interactions. Faculty, staff and graduate students contribute to interactions with local students and teachers. We have worked hard to develop mini-courses, summer camps, and engaging enrichment programs to offer to local teachers and all levels of students from public schools to home school programs. In the last five years 5,333 students and 141 teachers have participated in a learning experience presented by the faculty, staff, and students in CLA. The laboratory regularly hosts adult groups such as the Coffee County Leadership Program and the Precision Machinists. In addition, the graduate students have traveled to many schools in the community for events such as Friday School at Sewanee Elementary, Fantastic Fridays at Cowan Middle School and the Science Club at Shelbyville High School.

The ASM Materials Camp engaged high school students in learning about alternative energy strategies to performing a live play pertinent to the week’s activities in the auditorium.

TECH camp provided interactive, hands-on projects that facilitated career awareness and opened eyes to the excitement of scientific discovery to rising middle school students. The UTSI/CLA Computational Science camp hosted middle and high school students, as well as science and math teachers an opportunity to study computational astrophysics, meteorology, agriculture, genomics, epidemiology, pharmacokinetics, and programs using languages such as gnuplot, Perl, and NetLogo.

CLA has worked with the Tullahoma Hands On Science Center (HOSC) to provide educational experiences to alternative school students through a grant from the Peyback foundation. In 2010, UTSI teamed with the HOSC to win a grant to site a Fireball Network station at UTSI with an exhibit at the HOSC. The Fireball Network tracks meteors in the night sky. In 2010 UTSI moved its summer enrichment programs for younger learners to the HOSC as summer camp programs and assists in delivering those programs at the HOSC. Science teachers and HOSC Bill Boss

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Benchmark Data FY 2008-2012

Cumulative

FY 2008 FY 2009 FY 2010 FY 2011 FY 2012

Publications

Peer-reviewed articles 110 39 16 23 15 17

Book or book chapters 10 1 0 4 5 0

Presentations

International 38 13 1 8 7 9

National 128 27 9 10 28 54

Research Awards

External funding received $6,294,776 $1,073,818 $1,235,021 $1,676,546 $2,030,691 $278,700

THEC State Appropriations $4,526,732 $906,100 $883,900 $965,200 $913,468 $858,064

Research expenditures $6,402,456 $1,039,067 $1,280,931 $1,481,810 $1,395,390 $1,205,258

Research Accomplishments andFive year Benchmark Our research mission is growing. The funding provided by the Tennessee Higher

Education Commission, coupled with support from the university, provided valuable leverage

for sponsored research. The research awards continue to increase. This growth is possible

because of the dedication of our faculty and the support of THEC and UTSI.

CLA remains active in Outreach and Business Development. The faculty are active

in scientific conferences and local business meetings. Productivity among Center faculty

has been outstanding during the last five year period. During fiscal years 2008 through

2012, Center faculty published 110 peer-reviewed articles, 10 books and presented at 166

regional, national, and international meetings.

Comparative Summary of Accomplishments

Despite the current funding environment, Center faculty continue to make excellent

progress in ongoing projects, gaining national and international recognition for their

expertise and accomplishments. Details of current faculty research are provided in the

Faculty Reports section (pp. 13-21).

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Center faculty have successfully adapted to the increased competition for federal and

corporate funds. Total research funding increased greatly from $1,039,067 in 2008 to

$1,205,258 in 2012. This shift in funding reflects the faculty’s aggressive and successful

search for support in response to the increased competition for federal funds.

Human mesenchymal stem cells on a PCL gradi-ent array post pattern showing the agglomera-tion of cells at the high density area and the flat portion of the template. Green: f-actin, red: vincu-lin. Post positions are represented with red dots.

On the same template where the spacing forms rows, the hMECs align along rows of posts. Posts are highlighted with red x’s. Green: f-actin, red: vinculin.

Stem Cell Experiments on Combinatorial Polymers Formed from Laser Machined Templates

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Future Directions

The University of Tennessee Space Institute’s direction is changing from education

and research to research and education; placing the greater emphasis on externally

funded research. The Center for Laser Applications will follow that trend as well. We have

built a vibrant multi-disciplinary research team broadly working in photonics, biophotonics,

spectroscopy, laser materials interactions, plasma and non-equilibrium physics, fluid physics

and computational modeling. These efforts will continue. Moving forward, the goal of CLA will

be to involve more of the UTSI and UTK faculty and students in research using our laboratory

resources. Currently, exploratory research is carried out guided by the Principals in CLA. In

the future, exploratory research directions for the Center will be solicited from the faculty-

at-large in the form of white paper proposals, and resources will be allocated based on

this proposal process. We are confident that this plan will help serve the broader science

community.

Today, the Institute’s reduced size is such that maintaining separate accounting and

support functions for CLA is no longer efficient, and these functions will be absorbed into

the Institute’s infrastructure. The administrative savings will be applied to furthering the

research mission of CLA.

Laboratory space is one of CLA’s greatest assets and in the future we will work to

“broaden the tent” to make use of the facilities for more investigators. For example, we

look forward to working with UT Research Foundation’s ASSET program. CLA’s space and

infrastructure will contribute to the success of that program.

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CENTERS OF EXCELLENCE/ACTUAL, PROPOSED, AND REQUESTED BUDGET

University of Tennessee Space Institute, Center for Laser Applications

FY 2011-12 Actual FY 2012-13 Proposed FY 2013-14 Requested

Matching Appropr. Total Matching Appropr. Total Matching Appropr. Total

Expenditures 429,033 858,065 1,287,098 412,190 824,380 1,236,570 432,800 865,599 1,298,399

Salaries

Faculty 64,181 128,362 192,543 72,335 144,670 217,005 75,952 151,904 227,856

Other Professional 104,006 208,012 312,018 104,006 208,012 312,018 109,207 218,413 327,620

Clerical/ Supporting 39,466 78,931 118,397 39,466 78,931 118,397 41,439 82,878 124,317

Assistantships 29,523 59,046 88,569 29,523 59,046 88,569 30,999 61,998 92,997

Total Salaries 237,176 474,351 711,527 245,330 490,659 735,989 257,597 515,193 772,790

Fringe Benefits 65,707 131,413 197,120 65,824 131,648 197,472 69,115 138,230 207,345

Longevity 934 1,868 2,802 934 1,868 2,802 981 1,961 2,942

Total Personnel 303,817 607,632 911,449 312,088 624,175 936,263 327,693 655,384 983,077

Non-Personnel

Travel 14,733 36,707 51,440 18,026 36,052 54,078 15,580 31,160 46,740

Software 350 700 1,050 0 0 0 0 0 0

Books & Journals 0 0 0 0 0 0 0 0 0

Other Supplies 48,500 62,726 111,226 30,805 61,610 92,415 26,625 53,250 79,875

Equipment 8,591 30,094 38,685 49,570 99,140 148,710 42,844 85,687 128,531

Maintenance 1,051 65,733 66,784 2,254 46,926 49,180 1,948 3,895 5,843

Scholarships 38,686 27,780 66,466 16,448 32,897 49,345 14,217 28,433 42,650

Consultants 0 0 0 0 0 0 0 0 0

Renovation 0 0 0 0 0 0 0 0 0

Professional Membership 359 717 1,076 1,577 3,154 4,731 1,363 2,726 4,089

Media Process 781 1,561 2,342 1,126 2,253 3,379 974 1,948 2,922

Communication 704 1,408 2,112 0 0 0 0

Rentals 2,692 5,383 8,075 1,803 3,605 5,408 1,558 3,116 4,674

Contractual Services 7,733 15,465 23,198 0 0 0 0 0 0

Other Expenditures 0 80 80 0 0 0 0 0 0

Cost Share 1,040 2,079 3,119 0 0 0 0 0 0

Total Non-Personnel 125,220 250,433 375,653 121,609 285,637 407,246 105,109 210,215 315,324

GRAND TOTAL 429,037 858,065 1,287,102 433,697 909,812 1,343,509 432,802 865,599 1,298,401

Revenue

New State Appropriation 815,195 815,195 824,380 824,380 865,599 865,599

Carryover State Appropriation 128,302 128,302 85,432 85,432 0

New Matching Funds 429,037 429,037 433,697 433,697 432,802 432,802

Carryover from Previous Matching Funds 0 0 0

Total Revenue 429,037 943,497 1,372,534 433,697 909,812 1,343,509 432,802 865,599 1,298,401

CLA Budget

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Vision Science Research

For several years, Professor Chen’s biophysics vision research in CLA has pioneered the development of realistic computer-based eye modeling and ophthalmic simulation that ranges in application from the optical design of ophthalmic instrumentation to refractive surgery, intraocular lenses, spectacle lens, contact lens design, bio-optical engineering, and medical education. Professor Chen has been awarded two NIH research grants. The first grant is to develop a novel adaptive photorefraction technology to detect early keratoconus disorder, which is the major cause of failure in the US of LASIK, the popular laser surgery technique. The second grant supports the creation and development of realistic eye models for diseased eyes.

In 2008 and 2011, Professor Chen and Dr. J.W.L. Lewis obtained two U.S. patents through The University of Tennessee Research Foundation (UTRF) for the adaptive photoscreening (APS) technology. The figure below depicts the first prototype in pediatric application as it is designed to perform binocular automatic examinations without the use of medical professionals. The system includes a child-friendly screen that can display an animated video to attract the attention, to control the accommodation and ocular fixation, and to interact with examinees throughout the required infrared measurement procedures. The complete evaluation procedure includes assessments in binocular near- or far-sightedness, astigmatism, ocular motility/alignment, and optical opacity. The monocular design of the innovation makes possible the detection at cornea abnormalities, including dry eye, keratoconus, cataract, and corneal scars. Professor Chen collaborates with the Wang Vision Institute in Nashville to study adults’ eye diseases and to show the feasibility of the technique. In 2011, Professor Chen obtained the support from the Wal-Mart Vision Center in Tullahoma, TN for clinical studies of school-age children and, in 2012, to extend the clinical studies to preschool children as young as 3 years old. The children’s clinical study is supported by 2012 Maturation award of UTRF.

Currently Professor Chen is establishing and developing collaborations with several research groups in the Brain Institute and Eye Institute of Vanderbilt University to investigate the potential application of the APS detection of mental problems such as post traumatic stress disorder, dyslexia, and physical/emotional abuse through the ocular response and the hand-eye-stimulus interaction.

Ying-Ling ChenResearch Assistant ProfessorPhD, University of TennesseeSpace Institute

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Materials Science Research

Dr. Lino CostaResearch Assistant Professor of Materials Science and

Engineering

PhD, Instituto Superior Tecnico, Universidade Tecnica de Lisboa

Dr. Lino Costa’s research focuses primarily on developing functional surface-nanostructured polymer films for various applications. The nanostructures consist of large arrays of 10+ µm long sub-micrometer wide posts formed by polymer replication of femtosecond laser patterned fused silica templates.

Polymers used include polyethylene, cellulose acetate (CA), polyvinyl alcohol, polyvinyl chloride (PVC), and polyethylene terephthalate (PET). The pattern of the nanostructures machined on the template and the surface coatings applied to the polymer replicas are designed to fit the needs of the various applications. CA replicas with posts arranged in a gradient pattern and coated with a 200 nm thick layer of SiO

2 deposited using a novel sol-gel CVD

technique have been successfully used as substrates in cell interaction studies. CA, PVC and PET replicas containing over ten million posts per square centimeter arranged in a regular array and coated with nanometer thin layers of gold, platinum, palladium, or ultrathin layers of electroactive polymers such as PEDOT atop a layer of ITO, or a nanoporous layer of alumina or titania, are currently being developed for various applications ranging from sensors to large-surface area electrodes for photovoltaic and electrical energy storage purposes. The femtosecond laser patterned fused silica templates are also being explored as potential lab-on-a-chip devices for cell biology studies such as chemotaxis.

In addition, Dr. Costa is also involved in developing femtosecond laser machined microfluidic devices for cell biology studies, and in conducting exploratory studies on suitability of LISI coating and marking technology for external entities interested in improving the surface properties of metal objects.

SEM image of a gold-coated cellulose acetate replica, imaged at a 45° tilt.

Schematic of a roll-to-roll replication system for continuous fabrication of large area surface-nanostructured polymer films.

Group picture taken during the recent visit of Professor Weiping He from Northwestern Polytechnical University - Xi’an, Shaanxi Province - P. R. China to UTSI. Professor He visited UTSI to discuss research on two-dimensional symbol laser marking. From left to right: Dr. Shi, Professor He, Professor Davis, Professor Hofmeister, Professor Costa, Ms. Lansford. In the middle, Mr. Terekhov.

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The research of Professor Davis and his group spans a range of activities in the areas of laser applications for chemical analysis and biotechnology. Much of this work is built on the group’s earlier innovations in ultrasensitive fluorescence detection. Davis is a pioneer of experimental techniques in single-molecule fluorescence detection and spectroscopy, having co-developed the first experiments to successfully demonstrate detection of a single fluorophore in solution in the late 1980’s, the first single-molecule detection in a “lab-on-a-chip” device in the 1990’s, early experiments on single-molecule imaging for 3rd generation DNA sequencing in the early 2000’s, and novel single-molecule detection and trapping in nano-fluidic channels around 2008-2010. In the past year, one student from the group has graduated with a PhD for studies on single-molecule trapping in 1 and 2 dimensions; two other doctoral students are developing new techniques for trapping a single molecule in 3 dimensions (3-D); and four new graduate students will join the group this fall. The 3-D trapping will enable novel prolonged observations of a single emitter free to diffuse without confinement or tethering. The experiments rely on sub-diffraction imaging, in which the 3-D position of the emitter is measured more precisely than the diffraction limit of the microscope, together with real-time electrical control of solution flow in 3-D to counteract Brownian diffusion. The figure shows part of an apparatus in which astigmatic imaging provides the 3-D position of a single nanoparticle and a set of 4 micro-fabricated electrodes provide rapid switching of solution flow for trapping in 3-D.

Over the past year, several external collaborations have thrived, including an NSF-sponsored project with Vanderbilt University on ultrasensitive spectroscopy of nanoparticles for energy conversion applications, which grew from the 3-D trapping research. The methods for real-time control in the trapping experiments are also being applied in a project with JILA, UC Boulder, in which real-time computer control of optical forces from a focused infrared laser beam is used to sort mammalian cells in a microfluidic

device. The cells are being used for directed evolution of new red fluorescent proteins (RFPs) with enhanced photostability. Super-resolution imaging of single RFPs provides a means for visualizing nanoscale life processes inside cells, but further advances require development of the new improved RFPs. In other collaborations over the past year, with the Photon Factory, Auckland University; the Center for Nanophase Materials Science, at Oak Ridge National Laboratory; and with other faculty in the CLA, we are researching new methods for directly creating nano-channels and micro-channels with femtosecond lasers using special focusing conditions. We are collaborating with a company to commercialize this technology.

Lloyd M. DavisB. H. Goethert Professor of PhysicsPhD, University of Auckland, New ZealandVisiting Researcher at Vanderbilt UniversityVisiting Researcher at JILA, UC BoulderVisiting Researcher at the Photon Factory, University of AucklandUser/Visiting Researcher at CNMS, Oak Ridge National Laboratory

Ultrasensitive Spectroscopy

Microscope for trapping a single molecule in 3-D. The insets show a single nanoparticle between 4 tetrahedral-spaced electrodes and its image as its focal position is manipulated.

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Laser Materials Processing

Professor Hofmeister came to UTSI seven years ago to become Director of the Center for Laser Applications following eighteen years on the faculty of Vanderbilt University. His primary interest is in additive fabrication. Hofmeister was one of the developers of the Laser Engineered Net Shaping (LENSTM) process at Sandia National Laboratories and holds a patent for a feedback control system for that process. He is working with NASA, the US Air Force and Sciaky, Inc. to develop sensors and control strategies for additive manufacture using electron beam technologies. Two patents have been filed by NASA related to his innovations in electron beam control of additive manufacture.

Currently, Professor Hofmeister is developing femtosecond laser ablation techniques for the fabrication of micro and nanofluidic devices for biological applications. He is an External Associate of the Vanderbilt Institute for Integrative Biosystems Research (VIIBRE) and holds two patents for bioreactors with members of VIIBRE. CLA has a state-of-the-art nanofabrication facility in our clean room with a femtosecond laser coupled to a microscope with four axis nanopositioning stages. CLA has built devices for the study of cell migration during chemotaxis with the Janetopolis group in Vanderbilt’s Department of Biological Sciences. With Melissa Skala this collaboration was recently awarded a Discovery Grant for “Microfluidic Intravital Windows for Local Antiangiogenic Cancer Inhibition.” Dr. Hofmeister’s group is working on utilizing high aspect nanoholes to fabricate nanoneedles for in situ probing of intercellular function such as cell-cell and cell-matrix interactions with Prof. Hak-Joon Sung, Biomedical Engineering Vanderbilt School of Engineering and Prof. Ann Richmond, Cancer Cell Biology Vanderbilt Medical School.

Professor Hofmeister’s research in nucleation and solidification kinetics led to three space flight experiments in the 1990’s to study the effects of fluid flow on nucleation using the TEMPUS facility on IML-2, MSL-1, and MSL-1R. Dr. Hofmeister was principal investigator for the TEMPUS Incandescence Measurement Instrument Project, which designed and implemented an infrared pyrometer on the existing TEMPUS flight hardware. TEMPUS experiments were conducted by “telescience” operation in low earth orbit using modeling and simulation software which Dr. Hofmeister developed for the space flight experiments.

Professor Hofmeister is active in professional societies and outreach to the local community. He has served as Board President of the Tullahoma Hands on Science Center. He frequently works with the University of Tennessee Center for Industrial Services to assist local industry such as Fischer USA, Nissan, Walker Die Casting, Ace Pump, and Jarden Zinc, with materials related problem solving.

WILLIAM HofmeisterResearch Professor of Materials Science and Engineering

PhD, Vanderbilt UniversityAdjoint Professor of Electrical Engineering and Computer Science,

Vanderbilt UniversityUniversity of Canterbury Visiting Erskine Fellow, 2011

Fellow of ASM International

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Mössbauer Spectroscopy

Charles JohnsonAssociate Director, UTSI

Emeritus Professor of Physics, University of Liverpool, England

M.A., Oxford University, England

D. Phil., Oxford University, England

Dr. Charles Johnson uses magnetic hyperfine interactions to study solids. These produce huge magnetic fields of up to several thousand kG inside atoms. By comparison the earth’s magnetic field is 0.2 G, iron permanent magnets give 2 kG, rare earth permanent magnets 10 kG and superconducting magnets can produce 150 kG.

He made the first successful nuclear polarization experiment using the hyperfine field to orient radioactive 60Co nuclei in a paramagnetic crystal of cerium magnesium nitrate (CMN) at millikelvin temperatures and detected it by measuring the anisotropy of the emitted -rays. (Phil. Mag. 44 210 (1953)). The same system (60Co in CMN) was later used by Wu et al (Phys. Rev. 105 1413 (1957)) to observe the asymmetry of -emission. This confirmed the non-conservation of parity in weak interactions which had been proposed by Lee and Yang (Phys. Rev. 101 254 (1956)) for which they were awarded the 1957 Nobel Prize in physics. He also made the first measurement of the hyperfine field in a ferromagnet (Phil. Mag. 4 948 (1959)) and was the first to align nuclei using the electric quadrupole hyperfine interaction (Phys. Rev. 121 591 (1961)).

The discovery of the Mössbauer Effect opened up much wider possibilities of probing solids as it has much better resolution than nuclear orientation, and measures electric as well as magnetic fields, and does not require low temperatures. Shortly after the discovery Dr Johnson made the first systematic measurements of hyperfine fields in iron alloys (Phys. Rev. Letters 6 450 (1961)). He subsequently applied it to study problems in magnetism, chemistry, molecular biology, geology, archaeology and other fields. Mössbauer spectroscopy is now a

well established technique for probing materials. Work being carried out this year in the CLA includes the following applications to magnetic nanoparticles and nano-composites:

• the chemistry of europium chlorides • the properties of Eu2+ in Eu-doped fluorochlorozirconate glasses for use as optical activators for x-ray image plates • the blocking temperature of superparamagnetic EuS nanoparticles • iron oxide nanoparticles for medical and information storage applications

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Jacqueline JohnsonAssociate Professor

Materials Science and EngineeringB.Sc., University of Liverpool, EnglandPh.D., University of Liverpool, England

Transparent Storage Phosphor Materials for Mammography

Dr. Jacqueline Johnson continues to develop ZBLAN glass ceramics for x-ray imaging applications. This year has seen two significant breakthroughs. The first is the co-doping of holmium and europium in the materials, which has led to a tripling of the efficiency in luminescence in response to photostimulation. The result allows the glass ceramic plate to approach the efficiency of current polycrystalline plates while maintaining the previously found ultra-high resolution unique to these glass ceramics (Figure 1).

In situ transmission electron microscopy (TEM) has been performed on several glass ceramic samples in order to elucidate information on nanocrystal formation. Experiments on bulk materials have only revealed the development of BaCl

2 nanocrystals within the glass matrix. TEM has revealed a BaF

2 phase that

forms before the BaCl2 and instead of making the hexagonal to orthorhombic

phase transition as the BaCl2 does; BaF

2 makes an orthorhombic to face-

centered cubic transition as found from the diffractogram (Figure 2). As well as medical imaging plates, these materials can be used as a glass back layer to improve the efficiency of solar cells by converting two or more low energy photons into a single photon with more energy, i.e. as up-converters. Upon excitation with the light of a continuous wave (CW) laser diode operating at 1540 nm the Er3+-doped ZBLAN glasses show intense upconverted fluorescence (Figure 3).

In addition to ZBLAN as a glass matrix, Dr. Johnson’s group has explored borates as a potential host for rare earths. Although these glasses require higher melting temperatures, they are more robust than ZBLAN and have been explored for a down-converting top plate for solar cells. Figure 4 shows a samarium-doped borate glass under ultraviolet excitation.

New projects for the group include the development of nanoparticles for in vivo hyperthermia, sol gels as hosts for rare earth scintillators and glass ceramics for homeland security applications.

Beyond scientific research, Dr. Johnson continues to serve on review panels for the National Institutes of Health and the National Science Foundation in the United States and the Italian Ministry of Health and Romanian Research Council in Europe. For the next three years, she will serve on the Alfred R. Cooper Award nominations committee for the American Ceramic Society. Awards in 2011 include being elected a Fellow of the Institute of Physics and obtaining Patent: #, US 8,008,642: Computed Radiography System for Mammography.

Dr. Johnson is ably assisted in her work by graduate students Lee Leonard, Sharon Gray and Chris Foerster and summer interns, Tristan Harper, Dan Carpenter and Michael Cole.

Figure 1: PSl intensity with Eu doping and Eu/Ho codoping.

Figure 2: HRTEM image of BaF2

nanocrystal with diffractogram.

Figure 3: Er-doped ZBLAN glass ceramic under excitation of a CW laser diode.

Figure 4: Samarium-doped borate glass on a CdTe thin film solar cell under ultraviolet excitation.

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Nonequilibrium Fluid Physics

Dr. Trevor Moeller’s research focuses primarily on high temperature gases and plasmas, including both modeling and experimentation. He has successfully completed projects involving technology development for a portable MHD generator, design and testing of a thermal storage and management system for the U.S. Air Force, and development of an ultrasensitive electric propulsion thrust stand. His current research activities for the U.S. Air Force include modeling and analysis of probes for high-temperature, high-velocity flows in rockets and gas turbine engines, precise measurement of convective heat transfer coefficients for unique probe geometries, and investigations of cryodeposit contamination in cryopumped vacuum chambers. The sensitive nature of these programs precludes the presentation of further details. Dr. Moeller also is conducting research in the development of tools for the modeling of coupled electromagnetic/fluid systems.

Key future engineering technologies such as advanced propulsion, hypersonic flight, and fusion drive Dr. Moeller’s research. The accurate understanding, modeling and prediction of these technologies have motivated our new computational software and new theoretical framework. Our new software facilitates accurate quantitative modeling of plasma dynamics in complex-geometry, multidimensional problems, which permits us to resolve the complete multi-species, multiscale dynamics occurring within a plasma device both efficiently and accurately. We have successfully applied this new tool in investigations of high-

temperature, multi-species plasmas in shock tubes and are applying them presently to plasma propulsion systems and high-Mach flight simulations. We have also succeeded in applying this modeling software to capture full electrodynamics, gasdynamic devices, and low-conductivity plasma regions. Our new theoretical framework allows us to predict and understand the full multiscale dynamics within a plasma using classic analytical techniques. We are continuing to apply these new transformational tools to new problems in our drive to improve the state-of-the-art, and are pursuing new paths that will continue to extend our capabilities.

Trevor MoellerAssociate ProfessorPhD, University of TennesseeUTSI Program Coordinator for Mechanical, Aerospace, and Biomedical Engineering (MABE)

Probe in the exhaust of an afterburning gas turbine engine

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Molecular Recognition

Professor George Milton Murray is a Research Professor of Mechanical Aerospace and Biomedical Engineering at the University of Tennessee Space Institute. He came to UTSI in 2007 from Johns Hopkins University Applied Physics Laboratory. He specializes in chemical analysis, sensors and molecularly imprinted polymers. One of Professor Murray’s areas of expertise is the preparation of luminescent sensors for toxic compounds. The techniques of molecular imprinting and sensitized lanthanide luminescence have been combined to create the basis for a sensor that can selectively measure a specific organophosphorous compound. A complex of polymerizable sensitizing ligand europium [III) and an organophosphorous compound are copolymerized in a cross-linked polymer matrix. The best coordinators are trifluoromethyl-substituted b-diketones. The best polymerization mechanism is by Reversible Addition Fragmentation Transfer polymerization. This approach is allowing the production of soluble processable imprinted materials. Analogous methodologies are currently being applied to the production of sensors for the detection and determination of toxins, drugs of abuse, explosives and meat spoilage. Toxins are measured using piezo-electric transducers. Drugs are measured in an analogous manner to the nerve agents while explosives are being detected by the production of charge-transfer complexes between the explosives molecules, (acceptor) and immobilized amines (donor). Meat spoilage sensing is obtained using luminescence from a transition metal macrocyclic complex. All of the materials are also capable of providing highly selective binding sites to other transducers such as quartz crystal microbalance and surface plasmon resonance sensors.

Dr. Murray has published over 50 peer-reviewed papers in scientific journals as well as articles in the popular science press. He holds twenty U.S. patents and was named as one of the twenty Master Inventors of the Johns Hopkins University Applied Physics Laboratory. Dr. Murray’s research interests are centered on developing methods for the sequestration and ultra-trace determination of toxic or useful substances in real samples. The means to this goal involves the production of molecularly imprinted materials for sequestration and as specific polymer sensors. Laser spectroscopy is used for sensor transduction and verification. Laser processing is used to obtain specific form factors. Materials are also prepared for direct electronic or electrochemical transduction using electro-active polymers with imprinted polymer receptors.

George M. Murray Research Associate Professor

Materials Science and Engineering

PhD, University of Tennessee

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Professor Parigger has been affiliated with the Center for Laser Applications for over 25 years. His research interests include experimental and theoretical and computational Physics, particularly electromagnetic interactions, fundamental and applied spectroscopy, nonlinear optics, quantum optics, ultrafast phenomena, ultrasensitive diagnostics, lasers, combustion and plasma Physics, optical diagnostics, applied optics, biomedical applications, and in general atomic and molecular and optical (AMO) Physics. His Academic service activities included President of the Faculty Assembly at UTSI, Research Committee Chair at UTSI, Graduate Curriculum Committee in Physics, Graduate Council Policy Committee of The University of Tennessee, and Faculty Senate of The University of Tennessee, amongst other research, Masters and Dissertation committee engagements. Professor Parigger has been strongly engaged in postgraduate teaching, primarily doctoral research related courses for largely students of Physics and Engineering. He usually is active in peer review and publication related activities.

Christian Parigger’s research in the area of laser-induced breakdown spectroscopy, plasma and combustion Physics and diagnostics is ground breaking, well received and comprises a pioneering effort. His work is internationally and nationally well respected and recognized from a fundamental physics and laser applications point of view. His collaborations extend to international universities, to name a few, in Italy, Austria, Hungary, Russia, to several national universities, e.g., Auburn University, Arkansas State University, New Mexico State University, Denver University, University of Nebraska-Lincoln, University of Florida, and to National Laboratories including at Oak Ridge and at Albuquerque.

Christian Parigger’s recent research efforts continue to be comprised of various diagnostics applications in AMO

(Atomic Molecular Optical) Physics. As part of this effort, Dr. Parigger is committed to host the 22nd International Conference on Spectral Line Shapes (ICSLS) at UTSI in 2014. This conference is held bi-annually, alternating to occur in Europe and North America. The last few conferences were in France/Paris 2004, USA/Auburn 2006, Spain/Valladolid 2008, Canada/St. Johns 2010, and Russia/St. Petersburg 2012. The ICSLS22 will coincide with the 50-year UTSI and 30-year CLA celebrations in 2014. Contents include line shapes studies of atomic and molecular transitions in neutral gaseous mixtures, high and low temperature plasmas, spectroscopy of stellar atmospheres and interstellar media, cold atoms and molecules, collision-induced spectra, laser-induced breakdown spectroscopy, spectroscopy with ultra-short light pulses, applications to materials and biomedical studies, and/or combustion diagnostics.

Atomic and Molecular LaserSpectroscopyChristian PariggerAssociate Professor of Physics and Astronomy

PhD, University of Otago, Dunedin, New Zealand

Dr. rer.nat. in Physics, University of Innsbruck, Austria

Christian Parigger conducting laser research

Recorded and fitted spectra following laser-induced optical breakdown, N

e=0.5×1023m-3

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Awards, Appointments, Publications, Proceedings, Presentations and Patents for FY 2011-2012

Awards:J. A. Johnson, Fellow of the Institute of Physics, (2011).

R. L. Leonard, Wiley Student Blogger Scholarship, American Ceramic Society.

Appointments:C. Johnson, Appointed Honorary Visiting Professor of Physics, Australian Defense Force Academy, University of New South Wales, Canberra, ACT, Australia.

Publications Peer Reviewed Journals:Ying-Ling Chen, L. Shi, J. W. L. Lewis, and M. Wang, “Normal and diseased personal eye modeling using age-appropriate lens parameters,” Optics Express, Vol. 20, Issue 11, pp. 12498-12507 (2012).

L. Costa, A. Terekhov, D. Rajput, W. Hofmeister, D. Jowhar, G. Wright, and C. Janetopoulos, “Femtosecond laser machined microfluidic devices for imaging of cells during chemotaxis,” Journal of Laser Applications, Vol. 23, Issue 4, 042001 (2011).

D. Rajput, L. Costa, A. Terekhov, K. Lansford, W. Hofmeister, “Silica coating of polymer nanowires produced via nanoimprint lithography from femtosecond laser machined templates,” Nanotechnology, Vol. 23, No. 10, 105304 (2012).

J. K. R. Weber, M. Vu, C. Paßlick, S. Schweizer, D. E. Brown, C. E. Johnson and J. A. Johnson, “The oxidation state of europium in halide glasses,” J. Phys.: Condensed Matter, Vol. 23, No. 49, 495402 (2011).

C. E. Johnson and J. A. Johnson, “Fifty years of Mössbauer Spectroscopy: From alloys and oxides to glasses and nanoparticles,” Hyperfine Interactions, Vol. 204, Issue 1-3, pp. 47-55 (2012).

C. Paßlick, O. Müller, D. Lützenkirchen-Hecht, R. Frahm, J. A. Johnson and S. Schweizer, “Structural properties of fluorozirconate-based glass ceramics doped with multivalent europium,” J. Appl. Phys., Vol. 110, Issue 11, 113527 (2011).

R. L. Leonard, A. Y. Terekhov, C. Thompson, R. A. Erck and J. A. Johnson, “Anti-fog coating for a bronchoscope lens,” Surface Engineering Vol. 28, No. 6, pp. 468-472 (2012), DOI: 10.1179/1743294412Y.0000000007.

R. L. Leonard, S. A. Hasan, A. Y. Terekhov, C. Thompson, R. A. Erck, J. H. Dickerson and J. A. Johnson, “Protective coatings for enhanced performance in biomedical applications,” Surface Engineering, Vol. 28, No.7, pp. 473-479, (2012), DOI: 10.1179/1743294412Y.0000000018.

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A. Verma and G. M. Murray, “A Path to Soluble Molecularly Imprinted Polymers,” Journal of Functional Biomaterials, Vol. 3, Issue 1, pp. 1-22 (2012), DOI: 10.3390/jfb3010001.

Christian G. Parigger, “Computational Physics Activities at the University of Tennessee Space Institute,” Computing in Science & Engineering (CISE) Vol. 14, Issue 3, pp. 94-97, (May-June 2012) DOI. Bookmark: http://doi.ieeecomputersociety.org/10.1109/MCSE.2012.48.

Christian G. Parigger, A. Woods and J. O. Hornkohl, “Analysis of time-resolved superposed atomic hydrogen Balmer lines and molecular diatomic carbon spectra,” Applied Optics, Vol. 51, Issue 7, pp. B1-B6 (2012).

Christian G. Parigger and J. O. Hornkohl, “Computation of AlO B2S+gX2S+ emission spectra,” Spectrochimica Acta Part A: Molecular and Biomolecular Spectrosccopy, Vol. 81, Issue 1, 404-11, (July 2011) DOI:10.1016/j.saa.2011.06.029.

Robert Rhodes, Trevor Moeller, and Dennis Keefer, “Electrical Conductivity Measurements Via a Low-Voltage Conductivity Channel,” IEEE Transactions on Plasma Science, Vol. 40, Issue 4, pp. 972-979, (April 2012).

R. J. Thompson and T. M. Moeller, “Computer Simulations of Exothermic Propellants in a Microlaser Ablation Plasma Thruster,” Journal of Propulsion and Power, Vol. 28, No. 2, pp. 387–395 (2012).

R. J. Thompson and T. M. Moeller, “A Maxwell formulation for the equations of a plasma,” Physics of Plasmas, Vol. 19, Issue 1, pp. 010702-010702-4 (Jan 2012).

R. J. Thompson and T. M. Moeller, “Computational Investigations of Performance Improvements for Microlaser Ablation Plasma Thrusters Using Nozzles,” IEEE Transactions on Plasma Science, Vol. 39, No. 11, pp. 2932–2933, (Nov 2011).

Yuhong Xiong, William H. Hofmeister, John E. Smugeresky, Jean-Pierre Delplanque, Julie M. Schoenung, “Investigation of Atypical Molten Pool Dynamics in Tungsten Carbide-Cobalt During Laser Deposition using In-Situ Thermal Imaging,” Appl. Phys. Lett., Vol. 100, Issue 3, p. 034101 (Jan 2012).

Publications accepted and in press:D. Rajput, S. Crowder, L. Hofmeister, L. Costa, H-J. Sung, W. Hofmeister, “Cell Interaction Study Method Using Novel 3D Silica Nanoneedle Gradient Arrays,” Colloids and Surfaces B: Biointerfaces (2012).

G. Wright, L. Costa, A. Terekhov, W. Hofmeister, D. Jowhar, C. Janetopoulos, “On-Chip Open Microfluidic Devices for Chemotaxis Studies,” Microscopy and Microanalysis (2012).

C. E. Johnson, M. Vu, J. A. Johnson, D. E. Brown, J. K. R. Weber, C. Paßlick and S. Schweizer, “Mössbauer spectroscopy of europium-containing glasses: Optical activator study for x-ray image plates,” Accepted by Hyperfine Interactions (2011).

Christian G. Parigger, Alexander C. Woods, László Nemes, Anna Keszler and James O. Hornkohl, “Titanium Monoxide Spectroscopy Following Laser-Induced Optical Breakdown,” to be published: 2012 HPLA Online Book, American Institute of Physics (AIP), June 2012.

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Jesse M. Labello, Heard S. Lowry, L. M. Smith, Trevor M. Moeller, and Christian G. Parigger, “Modeling of Molecular Flux in a Space Simulation Chamber,” to be published: International Review of Atomic and Molecular Physics (IRAMP), July 2012.

R. J. Thompson and T. M. Moeller, “Classical Field Isomorphisms in Two-fluid Plasmas,” accepted for publication in Physics of Plasmas, July 2012.

Conference Proceedings:L. M. Davis, J. L. Lubbeck, K. M. Dean, A. E. Palmer, R. Jimenez, “Real-time analysis of multi-laser beam fluorescence for control of laser trapping forces in a microfluidic cell-sorting device,” Proceedings of SPIE PN100, PN100-40 (2012).

B. K. Canfield, J. K. King, W. N. Robinson, W. H. Hofmeister, S. A. Soper and L. M. Davis, “Ultrasensitive fluorescence correlation spectroscopy of highly parallelized microfluidic devices,” Proceedings of SPIE 8228, 8228-17, 1-9 (2012).

P. Kucheryavy, G. Goloverda, C. Stevens, L. Spinu, D. Lenormand, J. He, V. John, A. Burdin, C. E. Johnson, J. A. Johnson and V. Kolesnichenko, “Superparamagnetic iron oxide nanoparticles with variable size and iron oxidation states: synthesis and relaxivity studies,” Proceedings of Louisiana EPSCoR RII LA-SiGMA 2012 Symposium, Baton Rouge, LA, July 2012.

Nathan A. Bullock, Jonathan A. Merten, Cheyenne J. Sheppard, Matthew P. Jones, Christian G. Parigger, and Susan D. Allen, “Temporal evolution of the LIBS spectra of a representative nitro compound,” Federation of Analytical Chemistry and Spectroscopy Societies (FACSS)/Science Exchange (SCIX) and Society of Applied Spectroscopy (SAS), Kansas City, MO, Sep 2012.

Alexander C. Woods, Christian G. Parigger, and James O. Hornkohl, “LIBS: Measurement and Analysis of TiO Spectra,” Federation of Analytical Chemistry and Spectroscopy Societies (FACSS)/Science Exchange (SCIX) and Society of Applied Spectroscopy (SAS), Kansas City, MO, Sep 2012.

Christian G. Parigger and Jacqueline A. Johnson, “ On Optical Imaging of Tissue-Perfusion: Aspects of Photo-Acoustic Femtosecond Spectroscopy,” Invited, 34th Annual International Conference of the Institute of Electrical and Electronics Engineers (IEEE) Engineering in Medicine & Biology Society, San Diego, CA, Aug 2012.

Christian G. Parigger and Jacqueline A. Johnson, “On Optical Imaging of Tissue: Aspects of Photo-Acoustic Femtosecond Spectroscopy,” Late Breaking Research Poster, 34th Annual International Conference of the Institute of Electrical and Electronics Engineers (IEEE) Engineering in Medicine & Biology Society, San Diego, CA, Aug 2012.

Christian G. Parigger, Alexander C. Woods, László Nemes, Anna Keszler, and James O. Hornkohl, “Titanium Monoxide Molecular Spectra Following Laser-Induced Optical Breakdown,” Physics in the Wild West, International High-Power Laser Ablation (HPLA) Conference, Santa Fe, NM, May 2012.

Christian G. Parigger and Alexander C. Woods, “Hydrogen Balmer Series and Superposed Carbon Swan Spectra in Laser-Induced Plasma,” 21st International Conference on Spectral Line Shapes (ICSLS21), St. Petersburg, Russia, Jun 2012.

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Alexander C. Woods and Christian G. Parigger, “Identification and Analysis of Atomic and Molecular Superposition Spectra Following Laser-Induced Optical Breakdown,” Bulletin of the American Physical Society: 78th Annual Meeting of the Southeastern Section of the American Physical Society, Vol. 56, No. 9, Roanoke, VA, October 19-22, 2011.

Jesse M. Labello, “Calculation of Stationary, Free Molecular Flux Distributions in General 3D Environments,” Bulletin of the American Physical Society: 78th Annual Meeting of the Southeastern Section of the American Physical Society, Vol. 56, No. 9, Roanoke, VA, October 19-22, 2011.

Christian G. Parigger, Alexander C. Woods, Eugene Oks, James O. Hornkohl, Jonathan L. Height, Burl Donaldson and Walter Gill, “Atomic and Molecular Superposition Spectra Following Laser-Induced Optical Breakdown,” North American Symposium on Laser-Induced Breakdown Spectroscopy (NASLIBS), Clearwater, FL, Jul 2011.

Troy Anderson, C. Zuhlke, J. Bruce III, Denis Alexander and Christian G. Parigger, “Evidence of Near Field Filaments and Focusing Effects on Femtosecond LIBS,” North American Symposium on Laser-Induced Breakdown Spectroscopy (NASLIBS), Clearwater, FL, Jul 2011.

Alexander C. Woods, Christian G. Parigger, Eugene Oks, and James O. Hornkohl, “Analysis of Combined Atomic and Molecular Spectra,” Federation of Analytical Chemistry and Spectroscopy Societies (FACSS) Analytical Science and Innovation, Reno, NV, Oct 2011.

Jonathan L. Height, Burl Donaldson, Walter Gill, and Christian G. Parigger, “Measurements in solid propellant plumes at ambient conditions,” Proceedings of International Mechanical Engineering Congress & Exposition (IMECE) of the American Society of Mechanical Engineers (ASME), Denver, CO, Nov 2011.

Presentations - Conferences and Seminars:Ying-Ling Chen, Lei Shi, J. W. L. Lewis, Ming Wang, “Simulation of Fundus Image Measurements – One Step Toward Virtual Clinical Trial,” Invest Ophthalmol Vis Sci, 53: E-Abstract 5683, 2012.

Lei Shi, E. E. Hartmann, Naser T. Naser, J. W. L. Lewis, Ying-Ling Chen, Ming Wang, “Intraocular Scattering in Double-Pass Retinal Reflex,” Invest Ophthalmol Vis Sci, 53: E-Abstract 3052, 2012.

D. Rajput, L. Costa, A. Terekhov, K. Lansford, W. Hofmeister, “Fabrication of addressable biological devices using femtosecond laser machining,” 30th International Congress on Applications of Lasers & Electro-optics (ICALEO), Orlando, FL, October 23-27, 2011.

L. Costa, A. Terekhov, D. Rajput, W. Hofmeister, D. Jowhar, G. Wright, C. Janetopoulos, “Femtosecond laser micromachining of microfluidic devices for cell chemotaxis analysis,” 14th Annual Southeast Ultrafast Conference (SEUFC), Oak Ridge, TN, January 13-14, 2011.

L. Costa, K. Lansford, D. Rajput, W. Hofmeister, “Laser Induced Surface Improvement - LISI,” 16th Annual AAR Research Review, Pueblo Convention Center, CO, March 15-16, 2011.

D. Rajput, A. Terekhov, L. Costa, K. Lansford, W. Hofmeister; Nanoneedle Fabrication using Femtosecond Laser Machined Templates; 14th Annual Southeast Ultrafast Conference (SEUFC) – Oak Ridge, TN, January 13-14, 2011.

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D. Rajput, S. Crowder, L. Hofmeister, L. Costa, H-J Sung, and W. Hofmeister; Silica Nanoneedles as a Tool for Cell Behavioral Studies; MRS Fall Meeting & Exhibit - Boston, MA, November 28 - December 2, 2011.

D. Rajput, S. Crowder, L. Hofmeister, L. Costa, H-J Sung, and W. Hofmeister; Nanostructured Silica Functionalized Cell Culture Substrates; Sigma Xi Annual Meeting & International Research Conference - Raleigh, NC, November 10-13, 2011.

D. Szablewski, L. Costa, K. Lansford, D. Warnberg, W. Hofmeister, “LISI Cr-CrB2 Coatings in Heavy Axle Load

Applications,” 16th Annual AAR Research Review, Pueblo Convention Center, CO, March 15-16, 2011.

D. Szablewski, L. Costa, K. Lansford, D. Warnberg, W. Hofmeister, “Cr-CrB2 LISITM coatings as a rail protection

solution,” 30th International Congress on Applications of Lasers & Electro-optics (ICALEO), Orlando, FL, October 23-27, 2011.

L. Costa, A. Terekhov, W. Hofmeister, G. Wright, C. Janetopoulos, “Femtosecond laser machining of microfluidic devices for cell chemotaxis imaging,” 30th International Congress on Applications of Lasers & Electro-optics (ICALEO), Orlando, FL, October 23-27, 2011.

L. M. Davis, “Ultrasensitive fluorescence microscope developments,” Vanderbilt Institute for Integrative Biosystems Research and Education (VIIBRE), Vanderbilt University, Nashville, TN, July 9, 2012.

L. M. Davis, “Ultrasensitive microscope for nanoparticle studies,” TN-SCORE Annual Conference, Vanderbilt Marriott, Nashville, TN, June 15, 2012.

L. M. Davis, J. L. Lubbeck, K. M. Dean, A. E. Palmer, R. Jimenez, “Real-time analysis of multi-laser-beam fluorescence for timed control of laser tweezers in a microfluidic cell-sorting device,” Photonics North, Montreal, Canada, June 6–8, 2012.

L. M. Davis, “Cell sorting for directed molecular evolution,” Bioinstrumentation Engineering Analysis and Microscopy Laboratory, Massachusetts Institute of Technology, Cambridge, MA, June 4, 2012.

Jason King, James Germann, Brian Canfield, Lloyd M. Davis, “Three-dimensional Tracking and Trapping of Fluorescent Particles,” Poster Presentation at Huntsville Electro-Optical Society annual meeting ($500 1st prize for student posters), Huntsville, AL, April 20, 2012.

J. L. Lubbeck, K. M. Dean, L. M. Davis, A. E. Palmer, R. Jimenez, “Microfluidic cytometer for simultaneous high-throughput screening of fluorescent proteins on the basis of fluorescence lifetime, photostability, and brightness,” Biophysical Society 56th annual meeting, San Diego, CA, February 25–29, 2012.

B. K. Canfield, J. K. King, W. N. Robinson, W. H. Hofmeister, S. A. Soper and L. M. Davis, “Ultrasensitive fluorescence correlation spectroscopy of highly parallelized microfluidic devices,” SPIE BIOS 2012, International Symposium on Biomedical Optics, San Jose, CA, January 21–26, 2012; Proceedings of SPIE 8228, 8228-17, 1-9 (2012).

L. M. Davis, “Multichannel Fluorescence Detection and Correlation Spectroscopy,” Invited presentation at The Stower’s Institute for Medical Research, Kansas City, MO, December 9, 2011.

L. M. Davis, A. Terekhov, K. Lansford, J. Bradfield, C. Rohde, M.C. Simpson, B. Wright, “Rapid fabrication of long nanochannels with a single femtosecond laser pulse focused to a line,” Annual Meeting of the South East Section of the American Physical Society, Roanoke, Virginia, October 19-22, 2011.

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J. A. Germann, B. K. Canfield, J. K. King, A. Terekhov, L. M. Davis, “Three-dimensional flow measurements with a four-focus microscope,” Annual Meeting of the South East Section of the American Physical Society, Roanoke, Virginia, October 19-22, 2011.

J. K. King, B. K. Canfield, L. M. Davis, W. H. Hofmeister, “Microfluidic device for three-dimensional electrokinetic manipulation of single fluorescent molecules,” Annual Meeting of the South East Section of the American Physical Society, Roanoke, Virginia, October 19-22, 2011. B. K. Canfield, J. K. King, W. N. Robinson, W .H. Hofmeister, L. M. Davis, “Highly parallelized detection of single fluorescent molecules: simulation and experiment,” Annual Meeting of the South East Section of the American Physical Society, Roanoke, Virginia, October 19-22, 2011.

L. M. Davis, W. H. Hofmeister, L. Costa, A. Terekhov, B. K. Canfield, J. K. King, and D. Rajput, “Nanochannels, Nanoholes, and Nanowires,” 2011 Center for Nanophase Materials Science User Meeting, Chestnut Ridge Campus of Oak Ridge National Laboratory, Oak Ridge, Tennessee, September 19-20, 2011.

B. K. Canfield, J. K. King, W. H. Hofmeister, L. M. Davis, “Rapid fluorescence detection of single molecules in highly parallelized microfluidic devices,” [NIH 100-102], 7-th Inter-Institute Workshop on Optical Diagnostics and Biophotonic Methods from Bench to Bedside, National Institutes of Health, Bethesda, Maryland, September 15-16, 2011.

L. M. Davis, J. W. Bradfield, C. A. Rohde, and M. C. Simpson, “Machining of high-aspect micro/nano-channels with a single femtosecond laser pulse focused to a line,” IQEC/CLEO International Quantum Electronics Conference and Conference on Lasers and Electro-Optics, Asia/Pacific, Sydney, Australia, August 28–September 1, 2011.

J. L. Lubbeck, K. M. Dean, L. M. Davis, A. E. Palmer, R. Jimenez, “Directed evolution of the red fluorescent protein: Microfluidic cell sorter for dark-state conversion and photobleaching,” 242nd American Chemical Society National Meeting, Denver, CO, August 28–September 1, 2011.

L. M. Davis, B. K. Canfield, J. A. Germann, J. K. King, W. N. Robinson, “Three-dimensional flow manipulation in a microfluidic device for single-molecule trapping and characterization using four-beam fluorescence cross-correlation,” Weber Symposium, Lihue, Hawaii, June 12–17, 2011.

C. Johnson, “Mössbauer spectroscopy of europium-containing glasses,” 6th Nassau-Argonne International Mössbauer symposium, Garden City, NY, January 13-14, 2011. C. Johnson, “Mössbauer studies of europium glasses,” 7th Seeheim Workshop on Mössbauer Spectroscopy, Frankfurt, Germany, June 13-17, 2011.

C. E. Johnson and J. A. Johnson, “Fifty years of Mössbauer Spectroscopy: From alloys and oxides to glasses and nanoparticles”, 31st International Conference on the Applications of the Mössbauer Effect, Kobe, Japan, September 25-30, 2011.

C. Johnson, “Mössbauer studies of magnetic nanoparticles,” 36th Annual Condensed Matter and Materials Meeting, Charles Sturt University, Wagga Wagga, NSW, Australia, January 31–February 3, 2012.

Jacqueline A. Johnson, “Charge Collection and Photon Conversion for Radiation Sensing,” UTK & Y-12 Partnership in Technology Forum, Oak Ridge, TN, USA, April 5 & 6 2011.

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Publications

Jacqueline A. Johnson, Christian Paßlick and Stefan Schweizer, “ZBLAN glass ceramics for X-ray imaging,” PacRim 9 - The 9th International Meeting of Pacific Rim Ceramic Societies, Cairns, Australia, July 10-14, 2011.

Jacqueline A. Johnson, “Developing an x-ray image plate – engineering the material,” Seminar, Tennessee State University, Nashville, TN, USA, September 15, 2011.

Jacqueline A. Johnson, “Luminescent Materials for Medical, Defense and Solar Applications,” Seminar, University of the South, Sewanee, TN, USA, November 16, 2011.

Jacqueline A. Johnson, Christian Paßlick and Stefan Schweizer, “ZBLAN glass ceramics for X-ray imaging,” 36th International Conference and Exposition on Advanced Ceramics and Composites, Daytona Beach, FL, USA, January 22-27, 2012.

Jacqueline A. Johnson, “Luminescent Materials for Devices,” Austin Peay, Clarksville, TN, USA, Feb. 2, 2012.

Jacqueline A. Johnson, S. Gray, C. E. Johnson, R. Weber, C. Paßlick and S. Schweizer, “Study of Europium Valence in ZBLAN Imaging Plates,” Glass and Optical Materials Division Annual Meeting, American Ceramic Society, St. Louis, Missouri, USA, May 20-24, 2012.

Jacqueline A. Johnson, “Applications of Luminescent Materials,” Seminar, Xavier University, New Orleans, LA, USA, March 1, 2012.

Jacqueline A. Johnson, “Graduate and Intern Opportunities at the UT Space Institute,” Kentucky Nanotechnology Symposium, Bowling Green, KY, USA, March 31, 2012.

Carlos Alvarez, Yuzi Liu, Jacqueline Johnson and Amanda K. Petford-Long, “Evolution of Nanocrystals in Fluorochlorozirconate Glasses,” EMC Workshop 8: In situ and Environmental Science: How Can Electron Microscopy and Spectroscopy Help? Argonne National Laboratory Users Meeting, Argonne, USA, (May 2012).

C. Paßlick, J. A. Johnson and S. Schweizer, “Crystallization behaviour of rare-earth co-doped fluorochlorozirconate based glasses,” PacRim 9 - The 9th International Meeting of Pacific Rim Ceramic Societies, Cairns, Australia, (July 2011).

M. Vu, C. Alvarez, Y. Liu, A. K. Petford-Long and J. A. Johnson, “In Situ TEM Studies of Nanoparticle Growth in a Fluorozirconate (ZBLAN) Glass Matrix,” Microscopy & Microanalysis 2011 Meeting, Nashville, USA, (August 2011).

Christian Paßlick, Jacqueline A. Johnson and Stefan Schweizer, “Scintillation in multi-valent Eu-doped image plates,”11th International Conference on Inorganic Scintillators and their Applications SCINT 2011, Science Campus Justus-Liebig-University Giessen, Germany, (September 2011).

Marcel Dyrba, Paul-Tiberiu Miclea, Mihail Secu, Jacqueline Johnson and Stefan Schweizer, “Optical Properties of Samarium-doped Oxyfluoride Glasses Containing CaF

2 Nanocrystallites,” Materials Science & Technology

2011 Conference & Exhibition, Columbus, USA, (October 2011).

C. Alvarez, S. Gray, Y. Liu, A. K. Petford-Long and J. A. Johnson, “In Situ TEM Studies of Nanoparticle Growth in a Fluorozirconate (ZBLAN) Glass Matrix,” AVS 58th International Symposium & Exhibition, Nashville, USA, (November 2011).

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Publications

A. Eastes, L. Brothers and J. A. Johnson, “ZBLAN Glass: Improving Medical Imaging with Europium Doped HoF3 and SrCl2 Based Storage Phosphors,” National Conference on Undergraduate Research, Ogden, USA, (March 2012).

Carlos Alvarez, Yuzi Liu, Jacqueline Johnson and Amanda K. Petford-Long, “Evolution of Nanocrystals in Fluorochlorozirconate Glasses,” Argonne National Laboratory Users Meeting, Argonne, USA, (May 2012).

L. Leonard, C. Foerster, C. Alvarez, A. Petford-Long, R. Weber, C. Paßlick and S. Schweizer, “Crystallization studies of ZBLAN glasses by DSC and in situ TEM,” Glass and Optical Materials Division Annual Meeting, American Ceramic Society, St. Louis, USA, (May 2012).

C. Paßlick, J. A. Johnson and S. Schweizer, “Two-step annealing process for controlled barium halide crystallization in Eu-doped fluorozirconate-based glasses,” ISNOG 2012 - International Symposium on Non-Oxide and New Optical Glasses, Saint -Malo, France, (July 2012).

R. J. Thompson, T. Moeller, and C. L. Merkle, “A strong conservation formulation for finite volume plasma simulations with displacement and conduction current,” 43rd AIAA Plasmadynamics and Lasers Conference, New Orleans, LA, June 25-28, 2012.

R. J. Thompson and T. Moeller, “A novel set of unified Maxwell equations describing both fluid and electromagnetic behavior,” AIAA Plasmadynamics and Lasers Conference, New Orleans, LA, June 25-28, 2012.

Trevor Moeller, Robert Rhodes, Gregg R. Beitel, and Maurice M. May, “Prediction and Experimental Measurement of Total Temperature in an Afterburning Turbojet Exhaust,” Thermophysics and Heat Transfer Conference, New Orleans, LA, June 25-28, 2012.

R. J. Thompson and T. Moeller, “Numerical investigations of plasma actuator lorentz body forces,” 50th AIAA Aerospace Sciences Meeting including the New Horizons Forum and Aerospace Exposition, Nashville, TN, January 9-12, 2012.

Trevor Moeller, “ASSET,” Augmentor Design Systems Conference, Jacksonville, FL, Wednesday, March 21, 2012.

G. M. Murray, “Development of Colorimetric Imprinted Polymers for Explosive Detection,” Raptor Detection Technologies, Columbia, MD, January 10, 2012.

G. E. Southard and G. M. Murray, “Molecularly Imprinted Ion Exchange Resins,” Raptor Detection Technologies, Columbia, MD, May 16, 2012.

Christian G. Parigger and Alexander C. Woods, “Analysis of Atomic and Molecular Superposition Spectra and Applications in Flame Diagnostics,” Invited, Sandia National Laboratories, Albuquerque, NM, August 2011.

G. Wright, L. Costa, A. Terekhov, W. Hofmeister, D. Jowhar, C. Janetopoulos; Glass microfluidics for cell migration studies; Frontiers in Cell Migration & Mechanotransduction - NIH Natcher Conference Center, Main Auditorium, Building 45, Bethesda MD, May 24 - 26, 2011.

G. Wright, L. Costa, A. Terekhov, W. Hofmeister, D. Jowhar, C. Janetopoulos; Glass microfluidics for passive chemoattractant gradient generation; Microscopy & Microanalysis 2011 Meeting - Nashville, TN, August 7-11, 2011.

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Publications

G. Wright, D. Jowhar, A. Terekhov, L. Costa, W. Hofmeister, C. J. Janetopoulos; Open Microfluidics for Passive Gradient Generation; ASCB 2011 Annual Meeting - Colorado Convention Center, Denver, Colorado, December 3–7, 2011.

Milo Kral, Karl Buchanan, Craig Brice, Marcia Domack, Ravi Shenoy, William Hofmeister, “Characterization of electron beam deposited aluminum alloy 2139,” TMS Annual Meeting, Orlando, FL, March 11-15, 2012.

Patents, Patent Applications and Disclosures:“Computed Radiography System for Mammography,” Schweizer; Stefan, Johnson; Jacqueline A., Lubinsky; Anthony R., Patent No. U.S. 8,008,642, August 30, 2011.

“Molecularly Imprinted Polymer Ion Exchange Resins,” Murray; George M., Van Houten; Kelly A., Southard; Glen E., Patent No. U.S. 8,058,208, November 15, 2011.

“Processable Molecularly Imprinted Polymers,” G. E. Southard and G. M. Murray, European Patent No. EP1733211, January 11, 2012.

“Capillary perfused bioreactors with multiple chambers,” Wikswo; John P., Baudenbacher; Franz J., Prokop; Alex, Leboeuf; Eugene J., Chung; Chang Y., Cliffel; David, Haselton; Frederick R., Hofmeister; William H., Lin; Charles P., McCawley; Lisa J., Reiserer; Randall S., Stremler; Mark A., U.S. Patent number 8,003,378 B2, granted August 23, 2011.

“Microfluidic Devices for Chemotaxis, Methods of Making Same, and Applications of Same,” William Hudson Hofmeister, José Lino Vasconcelos da Costa, Alexander Terekhov, (VU1179USP1) U. S. Provisional Patent Application Number 61/624,910; filed April 16, 2012.

“Ultra high Aspect Ratio Nanostructures From Laser-Ablated Nanoholes,” W. H. Hofmeister, A. Y. Terekhov, J. L. Vasconcelos da Costa, K. S. Lansford, D. Rajput, L. M. Davis, U. S. Provisional Patent Application, U. S. Patent Office Serial No. 61/599,926; filed February 16, 2012.

“Line-Focus for Femtosecond Laser Machining,” L. M. Davis, U. S. Provisional Patent Application Number 61/639,644; filed 27 April, 2012.

“Optically Integrated Microfluidic Cytometers for High Throughput Screening of Photophysical Properties of Cells or Particles,” A. E. Palmer, R. Jimenez, K. M. Dean, J. L. Lubbeck, L. M. Davis, U. S. Utility Patent Application Number 13/360,706; filed 28 January, 2012.

“Molecularly Imprinted Polymer Ion Exchange Resins,” Murray; George M., Van Houten; Kelly A., Southard; Glen E., U. S. Published Patent Application 2012/0012,530, January 19, 2012.

“Polymer Based Lanthanide Luminescent Sensors for the Detection of Organophosphorus Compounds,” Murray; G. M., Uy; O. M. and Jenkins; A. L., U. S. Published Patent Application 20120164027, June 28, 2012.

“Medical Diagnostic and Surgery Using Femtosecond Laser Radiation,” Christian G. Parigger, J. Johnson and R. S. Splinter, University of Tennessee Research Foundation (UTRF) File PD 12092, Invention disclosure to UTRF, May 2012.

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Research Funded Externally

Investigator Contract Title Funding Agency Period of Performance Awarded

2011-2012Expended

Chen,Ying-Ling

Optical Investigation on Early Keratoconus Detection

(R02-4313026)

National Institutes of Health – Wang

Vision Institute

August 1, 2009 –July 31, 2012

$404,731 $83,393

Keratoconus Eye Model Bank for Virtual Clinical Trials and

Medical Educations(R02-4313027)

National Institutes of Health – National

Eye Institute

August 1, 2009 –August 31, 2012

$410,250 $161,063

Dynamic Ocular Evaluation System (DOES) Children Trial

(R02-4313028)

University of Tennessee Research

Foundation

January 9, 2012 –October 12, 2012

$15,000 $15,000

Davis, Lloyd High Throughput Microfluidic Systems for Drug Discovery/

Development of Assays for High Throughput Drug Discovery (R02-4318031)

National Institutes of Health/Louisiana

State University subcontract to UTSI

August 1, 2007 –July 31, 2011

$494,606 $68,575

Nanostructures for Enhancing Energy Efficiency, Tennessee Solar Conversion and Storage using Outreach,

Research and Education (TN-SCORE)

(R02-4318034)

National Science Foundation

August 15, 2010 –July 31, 2015

$88,678 $29,652

Hofmeister, William

E-Band Traveling Wave Tube Amplifier with Innovative

Carbon Nanotube Cathode(R02-4411038)

AFML/CFD Research

Corporation subcontract

February 18, 2011 –February 20, 2012

$30,000 $23,991

Closed-Loop Process Control for Electron Beam Direct

Manufacturing Phase I and Phase II

(R02-4411031 and 039

Sciaky, Inc. April 15, 2011 –February 28, 2013

$143,030 $63,093

SBIR Phase II – Electron Beam Direct Manufacturing

of Titanium Alloys(R02-4411040)

Sciaky, Inc. May 10, 2011 – February 28, 2013

$39,980 $13,236

Nanohair Supercapacitor Development

(R02-4411041)

University of Tennessee Research

Foundation

January 9, 2012 –October 12, 2012

$15,000 $15,000

Evaluation of Strain Hardening Exponent in a

Sprayed Copper Alloy(R02-4411042)

Exquadrum Corporation

March 1, 2012 –March 30, 2012

$4,000 $4,000

Laser Die Coating with Chromium

(R02-4411043)

International Copper Association,

Ltd

March 5, 2012 –September 30, 2012

$5,000 $5,000

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Research Funded Externally

Investigator Contract Title Funding Agency Period of Performance Awarded

2011-2012Expended

Johnson, Jacqueline

Advanced High-Resolution Two-Dimensional X-Ray

Detector for Mammography(R02-4417020)

National Institutes of Health

February 1, 2008 –November 30, 2012

$1,768,679 $258,567

Study of the Evolution of Nanoparticle Crystallization

and Optical Properties in Glass Ceramics(R02-4417022)

National Science Foundation

July 1, 2010 –June 30, 2013

$295,219 $87,279

Nanophase Glass Ceramic X-Ray Imaging Materials

(R02-4417024)

National Institutes of Health/Materials

Development, Inc. subcontract

October 1, 2010 –September 30, 2012

$30,000 $6,794

Moeller, Trevor

Cryo Deposition Research, Experimentation, and Development of Early

Warning and Mitigation Techniques

(R02-4348026)

Air Force/AEDC November 21, 2008 –December 31, 2012

$240,000 $67,637

Combined Recover Factor Model

(R02-4348028)

Air Force/AEDC May 20, 2009 –May 20, 2012

$35,000 $3,803

Integration & Technical Support to the 12V Vertical

Thrust Integration(R02-4348033)

Air Force/AEDC September 22, 2010 –September 30, 2012

$60,000 $7,775

Test-Plan: Cryogenic Composite Cylinder

(R02-4348034)

Gloyer-Taylor Laboratories, LLC

May 16, 2011–September 30, 2011

$18,554 $9,959

Exhaust of J85 Turbojet Engine

(R02-4348035)

Aerospace Testing Alliance

August 17, 2011 –December 31, 2011

$5,000 $5,000

Characterization of Heat Transfer Coefficient

Uncertainty in Support of High Temperature Probe Measurement Technology

R02-4348036

Air Force/AEDC March 19, 2012 – September 30, 2012

$42,500 $24,805

NASA Tennessee Space Grant Consortium (R02-4320026)

Vanderbilt University

June 14, 2010 –June 13, 2015

$127,143 $28,829

Murray, George

Soluble Molecularly Imprinted Polymers for Biomedical

Applications(R02-4419023)

Ambiocore, Inc. July 29, 2010 –July 28, 2011

$401,879 $102,603

Development of Polymer for Detection of Chlorate

(R02-4419024)

Raptor Detection, Inc.

January 10, 2012 –October 31, 2012

$187,200 $121,566

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33

Research Funded Externally

Investigator Contract Title Funding Agency Period of Performance Awarded

2011-2012Expended

Johnson, Jacqueline

Advanced High-Resolution Two-Dimensional X-Ray

Detector for Mammography(R02-4417020)

National Institutes of Health

February 1, 2008 –November 30, 2012

$1,768,679 $258,567

Study of the Evolution of Nanoparticle Crystallization

and Optical Properties in Glass Ceramics(R02-4417022)

National Science Foundation

July 1, 2010 –June 30, 2013

$295,219 $87,279

Nanophase Glass Ceramic X-Ray Imaging Materials

(R02-4417024)

National Institutes of Health/Materials

Development, Inc. subcontract

October 1, 2010 –September 30, 2012

$30,000 $6,794

Moeller, Trevor

Cryo Deposition Research, Experimentation, and Development of Early

Warning and Mitigation Techniques

(R02-4348026)

Air Force/AEDC November 21, 2008 –December 31, 2012

$240,000 $67,637

Combined Recover Factor Model

(R02-4348028)

Air Force/AEDC May 20, 2009 –May 20, 2012

$35,000 $3,803

Integration & Technical Support to the 12V Vertical

Thrust Integration(R02-4348033)

Air Force/AEDC September 22, 2010 –September 30, 2012

$60,000 $7,775

Test-Plan: Cryogenic Composite Cylinder

(R02-4348034)

Gloyer-Taylor Laboratories, LLC

May 16, 2011–September 30, 2011

$18,554 $9,959

Exhaust of J85 Turbojet Engine

(R02-4348035)

Aerospace Testing Alliance

August 17, 2011 –December 31, 2011

$5,000 $5,000

Characterization of Heat Transfer Coefficient

Uncertainty in Support of High Temperature Probe Measurement Technology

R02-4348036

Air Force/AEDC March 19, 2012 – September 30, 2012

$42,500 $24,805

NASA Tennessee Space Grant Consortium (R02-4320026)

Vanderbilt University

June 14, 2010 –June 13, 2015

$127,143 $28,829

Murray, George

Soluble Molecularly Imprinted Polymers for Biomedical

Applications(R02-4419023)

Ambiocore, Inc. July 29, 2010 –July 28, 2011

$401,879 $102,603

Development of Polymer for Detection of Chlorate

(R02-4419024)

Raptor Detection, Inc.

January 10, 2012 –October 31, 2012

$187,200 $121,566

Investigator Contract Title Funding Agency Period of Performance

Awarded 2011-2012Expended

Murray, George

Molecularly Imprinted Films for the Determination of Fatty Acid Methylesters

(R02-4419025)

AlphaSense, Inc. June 21, 2012 –December 21, 2012

$20,000 -0-

Parigger, Christian

Analysis and Presentation of AIO Flame Experiments

(R02-4334021)

Sandia National Laboratory

April 10, 2012 – October 5, 2012

$5000 1,915