4-Hydroxy-DIPTThe Drug Enforcement Administration's Special Testing and Research Laboratory

generated this monograph using structurally confirmed reference material.

Page 1 of 5SWGDRUG.org/monographs.htmLatest Revision: 1/5/2015

NH

NCH3

CH3CH3

CH3

OH

1. GENERAL INFORMATION

IUPAC Name:

CAS#:

Synonyms:

Source:

Appearance:

UVmax(nm):

3-[2-(diisopropylamino)ethyl]-1H-indol-4-ol

63065-90-7

4-OH-DIPT, 4-HO-DIPT, iprocin, 4-hydroxy-N,N-diisopropyltryptamine

DEA Reference Material Collection

White powder

Not Determined

2. CHEMICAL AND PHYSICAL DATA

2.1 CHEMICAL DATA

Form Chemical Formula Molecular Weight Melting Point (oC)

Base C16H24N2O 260 Not Determined

HCl C16H24N2O. HCl 296 283.2

4-Hydroxy-DIPTThe Drug Enforcement Administration's Special Testing and Research Laboratory

generated this monograph using structurally confirmed reference material.

Page 2 of 5SWGDRUG.org/monographs.htmLatest Revision: 1/5/2015

3. QUALITATIVE DATA

3.1 NUCLEAR MAGNETIC RESONANCE

Sample Preparation: Dilute analyte to ~5 mg/mL in base extracted CDCl3 containing TMS for 0 ppm reference.Instrument: 400 MHz NMR spectrometerParameters: Spectral width: at least containing -3 ppm through 13 ppm

Pulse angle: 90o

Delay between pulses: 45 seconds

1H NMR: 4-OH DIPT HCl Lot SF06008; CDCl3; 400MHz

7 6 5 4 3 2 1 0

0

1

2

3

4

5

6

7

8

9

10

12222121

CHCl3

TMS

1.050 1.000

12

7.00 6.75

0

0.25

0.50

0.75

121

3.1 3.0 2.9 2.8

222

4-Hydroxy-DIPTThe Drug Enforcement Administration's Special Testing and Research Laboratory

generated this monograph using structurally confirmed reference material.

Page 3 of 5SWGDRUG.org/monographs.htmLatest Revision: 1/5/2015

3.2 GAS CHROMATOGRAPHY/MASS SPECTROMETRY

Sample Preparation: Dilute analyte ~4 mg/mL methanol.

Instrument: Agilent gas chromatograph operated in split mode with MS detectorColumn: DB-1 MS (or equivalent); 30m x 0.25 mm x 0.25 mmCarrier Gas: Helium at 1 mL/minTemperatures: Injector: 280oC

MSD transfer line: 280oCMS Source: 230oCMS Quad: 150oCOven program:

1) 100oC initial temperature for 1.0 min2) Ramp to 300oC at 12 oC/min3) Hold final temperature for 9.0 min

Injection Parameters: Split Ratio = 20:1, 1 mL injectedMS Parameters: Mass scan range: 30-550 amu

Threshold: 100Tune file: stune.uAcquisition mode: scan

Retention Time: 14.502 minEI Mass Spectrum: 4-OH-DIPT HCl Lot # SF06008

m/z260240220200180160140120100806040

[x 1

05]

Inte

nsity

0.5

1.0

1.5

260

260

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229

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17416

016

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016

0146146

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130

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114

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919191 9191919191 9191919191 9191919191 91919191868686 8686868686 8686868686 8686868686 86868686777777 7777777777 7777777777 7777777777 77777777

727272 7272727272 7272727272 7272727272 72727272656565 6565656565 6565656565 6565656565 65656565

565656 5656565656 5656565656 5656565656 56565656

434343 4343434343 4343434343 4343434343 43434343

303030 3030303030 3030303030 3030303030 30303030

EI+

4-Hydroxy-DIPTThe Drug Enforcement Administration's Special Testing and Research Laboratory

generated this monograph using structurally confirmed reference material.

Page 4 of 5SWGDRUG.org/monographs.htmLatest Revision: 1/5/2015

3.3 INFRARED SPECTROSCOPY (FTIR)

Insrument: FTIR with diamond ATR attachment (1 bounce)Scan Parameters: Number of scans: 32

Number of background scans: 32Resolution: 4 cm-1

Sample gain: 8Aperture: 150

FTIR ATR (Diamond, 1 Bounce): 4-OH-DIPT HCl Lot SF06008

Wavenumber (cm-1)3500 3000 2500 2000 1500

%Tr

ansm

ittan

ce

20

30

40

50

60

70

3240324032403240324032403240324032403240324032403240324032403240324032403240324032403240 3147

314731473147314731473147314731473147314731473147314731473147314731473147314731473147

2943294329432943294329432943294329432943294329432943294329432943294329432943294329432943

2669266926692669266926692669266926692669266926692669266926692669266926692669266926692669

1589158915891589158915891589158915891589158915891589158915891589158915891589158915891589 1452

145214521452145214521452145214521452145214521452145214521452145214521452145214521452

14331433143314331433143314331433143314331433143314331433143314331433143314331433143314331396139613961396139613961396139613961396139613961396139613961396139613961396139613961396 1350

135013501350135013501350135013501350135013501350135013501350135013501350135013501350

1294129412941294129412941294129412941294129412941294129412941294129412941294129412941294

1261126112611261126112611261126112611261126112611261126112611261126112611261126112611261

1161116111611161116111611161116111611161116111611161116111611161116111611161116111611161 1130

113011301130113011301130113011301130113011301130113011301130113011301130113011301130

1038103810381038103810381038103810381038103810381038103810381038103810381038103810381038

968968968968968968968968968968968968968968968968968968968968968968 843

843843843843843843843843843843843843843843843843843843843843843

735735735735735735735735735735735735735735735735735735735735735735

661661661661661661661661661661661661661661661661661661661661661661582582582582582582582582582582582582582582582582582582582582582582

490490490490490490490490490490490490490490490490490490490490490490

Wavenumber (cm-1)1700 1600 1500 1400 1300 1200 1100 1000 900 800 700

%Tr

ansm

ittan

ce

20

30

40

50

60

70

1589158915891589158915891589158915891589158915891589158915891589158915891589158915891589

1506150615061506150615061506150615061506150615061506150615061506150615061506150615061506 1452

145214521452145214521452145214521452145214521452145214521452145214521452145214521452

14331433143314331433143314331433143314331433143314331433143314331433143314331433143314331396139613961396139613961396139613961396139613961396139613961396139613961396139613961396 1350

135013501350135013501350135013501350135013501350135013501350135013501350135013501350

1319131913191319131913191319131913191319131913191319131913191319131913191319131913191319

1294129412941294129412941294129412941294129412941294129412941294129412941294129412941294

1261126112611261126112611261126112611261126112611261126112611261126112611261126112611261

1161116111611161116111611161116111611161116111611161116111611161116111611161116111611161 1130

113011301130113011301130113011301130113011301130113011301130113011301130113011301130

1093109310931093109310931093109310931093109310931093109310931093109310931093109310931093

1049104910491049104910491049104910491049104910491049104910491049104910491049104910491049

1038103810381038103810381038103810381038103810381038103810381038103810381038103810381038

968968968968968968968968968968968968968968968968968968968968968968 843

843843843843843843843843843843843843843843843843843843843843843

785785785785785785785785785785785785785785785785785785785785785785756756756756756756756756756756756756756756756756756756756756756756

735735735735735735735735735735735735735735735735735735735735735735

694694694694694694694694694694694694694694694694694694694694694694 661

661661661661661661661661661661661661661661661661661661661661661

634634634634634634634634634634634634634634634634634634634634634634604604604604604604604604604604604604604604604604604604604604604604 582

582582582582582582582582582582582582582582582582582582582582582

517517517517517517517517517517517517517517517517517517517517517517490490490490490490490490490490490490490490490490490490490490490490

The Drug Enforcement Administrations Special Testing and Research Laboratorygenerated this monograph using structurally confirmed reference material.

Page 5 of 5SWGDRUG.org/monographs.htmLatest Revision: 1/5/2015

http://forendex.southernforensic.org/index.php/detail/index/1175

http://en.wikipedia.org/wiki/4-HO-DiPT

4. ADDITIONAL RESOURCES

Forendex

Wikipedia