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40% Glucose Gel Sugar Up SandBox Medical LLC T 781.826.6905 | 877.396.1551 [email protected] sandboxmedical.com In multiple studies, 40% glucose has been found effective in raising babies’ low blood sugar and helps mobilize the baby’s own glucose stores. Together with breastfeeding, or feeding expressed breast milk or formula, oral administration of 40% glucose has been shown to increase blood sugar levels while reducing intravenous dextrose therapy and NICU admissions. 1,2,3,4,5 Formulated for babies, without xanthan gum, artificial colors or flavors Thick formulation stays on gloved finger for easy administration to buccal mucosa • Inexpensive and simple to administer Helps avoid NICU admission for intravenous glucose Calculate weight specific dose per hospital protocol Why choose xanthan gum-free SugarUp? SugarUp 40% glucose gel gives you all the convenience of the commercial products without the risk of xanthan gum. Commercially available 40% glucose in tubes often contain artificial coloring, flavoring and xanthan gum.*** • Oral administration • Single-patient use • No artificial colors or flavors • Does not contain xanthan gum, which has been shown to cause necrotizing enterocolitis*** Made in USA Neonatal hypoglycemia is a common problem that affects up to 15% of other - wise healthy babies and is a leading cause of preventable brain damage in infants. Current practice includes additional feedings and frequent blood glucose checks. Some newborns however require intravenous glucose adminis - tered in an intensive care setting, which interferes with mother-infant bonding and the establishment of breast-feeding. Journal of Clinical Neonatology Vol. 3 Issue 1 January-March 2014 reduction in neonate admissions to the NICU for the primary diagnosis of hypoglycemia after…administration of glucose gel. Bennett et al 5 ** 88% 73% Administration of glucose gel reversed neonatal hypoglycemia in of neonates. Sugar Babies Study, Harris et al 1 ** Allows babies to stay with their mothers for breastfeeding and helps avoid NICU admission * Each syringe contains approximately 2.25ml of gel 2.25ml* Prefilled Oral-Only Syringe With Preservatives Individually Bagged

5-17021-004G SugarUp Datasheet - SandBox Medicalsandboxmedical.com/PDF/5-17021-004-SugarBabies-40-Glucose-Datasheet.pdflow blood sugar and helps mobilize the baby’s own glucose stores

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Page 1: 5-17021-004G SugarUp Datasheet - SandBox Medicalsandboxmedical.com/PDF/5-17021-004-SugarBabies-40-Glucose-Datasheet.pdflow blood sugar and helps mobilize the baby’s own glucose stores

40% Glucose GelSugarUp™

SandBox Medical LLC T 781.826.6905 | 877.396.1551 [email protected] sandboxmedical.com

In multiple studies, 40% glucose has been found effective in raising babies’ low blood sugar and helps mobilize the baby’s own glucose stores. Together with breastfeeding, or feeding expressed breast milk or formula, oral administration of 40% glucose has been shown to increase blood sugar levels while reducing intravenous dextrose therapy and NICU admissions. 1,2,3,4,5

• Formulated for babies, without xanthan gum, artificial colors or flavors

• Thick formulation stays on gloved finger for easy administration to buccal mucosa

• Inexpensive and simple to administer

• Helps avoid NICU admission for intravenous glucose

• Calculate weight specific dose per hospital protocol

Why choose xanthan gum-free SugarUp? SugarUp 40% glucose gel gives you all the convenience of the commercial products without the risk of xanthan gum. Commercially available 40% glucose in tubes often contain artificial coloring, flavoring and xanthan gum.***

• Oral administration• Single-patient use• No artificial colors

or flavors• Does not contain

xanthan gum, which has been shown to cause necrotizing enterocolitis***

Made in USA

Neonatal hypoglycemia is a common problem that affects up to 15% of other-wise healthy babies and is a leading cause of preventable brain damage in infants. Current practice includes additional feedings and frequent blood glucose checks. Some newborns however require intravenous glucose adminis-tered in an intensive care setting, which interferes with mother-infant bonding and the establishment of breast-feeding. Journal of Clinical Neonatology Vol. 3 Issue 1 January-March 2014

reduction in neonate admissions to the NICU for the primary diagnosis of hypoglycemia after…administration of glucose gel. Bennett et al 5 **

88%

73%

Administration of glucose gel reversed neonatal hypoglycemia in of neonates. Sugar Babies Study, Harris et al 1 **

Allows babies to stay with their mothers for breastfeeding and helps avoid NICU admission

* Each syringe contains approximately 2.25ml of gel

2.25ml* Prefilled Oral-Only Syringe

With Preservatives

Individually Bagged

Page 2: 5-17021-004G SugarUp Datasheet - SandBox Medicalsandboxmedical.com/PDF/5-17021-004-SugarBabies-40-Glucose-Datasheet.pdflow blood sugar and helps mobilize the baby’s own glucose stores

SandBox Medical LLC T 781.826.6905 | 877.396.1551 [email protected] sandboxmedical.com

Hospital Ordering Information | Contact us at: [email protected]

Need a Protocol for 40% Glucose?Email us at orders@sandboxmedical to request copies of protocols found in clinical literature or to share your protocol.

May be recycled with other #5 plastics (polypropylene).

NOTE: 40% glucose is considered a food and does not have an NDC number. The FDA has not reviewed or approved of the use of 40% glucose in neonates and has not reviewed 40% glucose for effectiveness in raising low blood sugar.

5-17021-004G

Item # Description Quantity

SB17022250 2.25ml* in 3ml oral-only syringe, 40% Glucose gel, with preservatives Box of 250

SB17022100 2.25ml* in 3ml oral-only syringe, 40% Glucose gel, with preservatives Box of 100

40% Glucose GelSugarUp™

Calculate weight specific dose per hospital protocol.

Clinical references* Each syringe contains approximately 2.25ml of gel.** Clinical references are for educational and informational purposes only and are not meant to imply endorsement of the SandBox Medical 40%

glucose solution.*** Beal J, Silverman B, Bellant J, Young TE, Kontz K. Late onset necrotizing enterocolitis in infants following use of a xanthan gum-containing thickening

agent. J Pediatr 2012;161:354-61. Harris DL, Weston PJ, Signal M, et al. Dextrose gel for neonatal hypoglycaemia (the Sugar Babies Study): a randomised, double-blind, placebo-

controlled trial. Lancet. 2013; 382:2077–83. [PubMed: 24075361] 2. Rawat M, Chandrasekharan P, Turkovich S, et al. Oral dextrose gel reduces the need for intravenous dextrose therapy in neonatal hypoglycemia.

Biomed Hub. 2016:1.3. Stewart CE, Sage EL, Reynolds P. Supporting ‘Baby Friendly’: a quality improvement initiative for the management of transitional neonatal hypogly-

caemia. Arch Dis Child Fetal Neonatal Ed. 2016; 101:F344–7. [PubMed: 26644391] 4. Harris DL, Weston PJ, Harding JE. Incidence of neonatal hypoglycemia in babies identified as at risk. J Pediatr. 2012; 161:787–91. [PubMed: 22727868] 5. Implementing a Protocol Using Glucose Gel to Treat Neonatal Hypoglycemia Bennett, CatherineFagan, ElyseChaharbakhshi, EdwinZamfirova,

InaFlicker, Jai et al. Nursing for Women's Health , Volume 20 , Issue 1 , 64 - 74

* Each syringe contains approximately 2.25ml of gel

Specifications Prefilled Oral-Only SyringesBarcoded, Individually Bagged. Each 3ml oral-only syringe contains 2.25ml* of gel. Gel formulation: 40% dextrose (D-glucose), USP purified water, glycerine, maltodextrin, carboxymethyl cellulose, methylparaben & potassium sorbate (preservatives), citric acid & NACL (sodium chloride) (buffers). 24 month shelf life in unopened polybags. Latex free, DEHP free, BPA free. Gel made and packaged in the USA. Syringe made in China.Note: Preservatives are the same as used in SweetUms™ 24% Sucrose solution.