5-MeO-MiPTThe Drug Enforcement Administration's Special Testing and Research Laboratory

generated this monograph using structurally confirmed reference material.

Page 1 of 6SWGDRUG.org/monographs.htmLatest Revision: 5/27/2014

NH

N

CH3

CH3

CH3

OCH3

1. GENERAL INFORMATION

IUPAC Name: N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-N-methylpropan-2-amine

CAS#: 96096-55-8 (base)

Synonyms: 5-methoxy-N-methyl-N-isopropyltryptamine

Source: DEA Reference Material Collection

Appearance: White Powder (base)

UVmax (nm): Not Determined

2. CHEMICAL AND PHYSICAL DATA

2.1 CHEMICAL DATA

Form Chemical Formula Molecular Weight Melting Point (oC)

Base C15H22N2O 246 243.7

HCl C15H22N2O. HCl 282 Not Determined

5-MeO-MiPTThe Drug Enforcement Administration's Special Testing and Research Laboratory

generated this monograph using structurally confirmed reference material.

Page 2 of 6SWGDRUG.org/monographs.htmLatest Revision: 5/27/2014

3. QUALITATIVE DATA

3.1 NUCLEAR MAGNETIC RESONANCE

Sample Preparation: Dilute analyte to ~5 mg/mL in deuterium oxide (D2O) containing TSP for 0 ppmreference and maleic acid as quantitative internal standard.

Instrument: 400 MHz NMR spectrometerParameters: Spectral width: at least containing -3 ppm through 13 ppm Pulse angle: 90o

Delay between pulses: 45 seconds1H NMR: 5-MeO-MiPT; Lot SF1797; D2O; 400 MHz

7.5 7.0 6.5 6.0 5.5 5.0 4.5 4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.5 0

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633231111

TSPMaleic acid (ISTD) HOD

Chemical Shift (ppm)

5-MeO-MiPTThe Drug Enforcement Administration's Special Testing and Research Laboratory

generated this monograph using structurally confirmed reference material.

Page 3 of 6SWGDRUG.org/monographs.htmLatest Revision: 5/27/2014

1H NMR: 5-MeO-MiPT; Lot SF1797; D2O; 400 MHz

7.45 7.40 7.35 7.30 7.25 7.20 7.15 7.10 7.05 7.00 6.95

0

0.5

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1111

3.900 3.875

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3.70 3.65 3.60 3.55 3.50

0

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6

Chemical Shift (ppm)

3.2 Gas Chromatography/Mass Spectrometry

Sample Preparation: Dilute analyte ~ 1 mg/mL base extracted into chloroform

Instrument: Agilent gas chromatograph operated in split mode with MS detectorColumn: DB-1 MS (or equivalent); 30m x 0.25 mm x 0.25 µmCarrier Gas: Helium at 1 mL/minTemperatures: Injector: 280oC MSD transfer line: 280oC MS Source: 230oC MS Quad: 150oC

5-MeO-MiPTThe Drug Enforcement Administration's Special Testing and Research Laboratory

generated this monograph using structurally confirmed reference material.

Page 4 of 6SWGDRUG.org/monographs.htmLatest Revision: 5/27/2014

Oven program: 1) 100oC initial temperature for 1.0 min 2) Ramp to 300oC at 12 oC/min 3) Hold final temperature for 9.0 minInjection Parameters: Split Ratio = 20:1, 1 µL injectedMS Parameters: Mass scan range: 30-550 amu Threshold: 100 Tune file: stune.u Acquisition mode: scanRetention Time: 13.357 min

EI Mass Spectrum: 5-MeO-MiPT; Lot H-0413

m/z240220200180160140120100806040

[x 1

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909090 9090909090 9090909090 9090909090 90909090868686 8686868686 8686868686 8686868686 86868686

777777 7777777777 7777777777 7777777777 77777777707070 7070707070 7070707070 7070707070 70707070636363 6363636363 6363636363 6363636363 63636363565656 5656565656 5656565656 5656565656 56565656

444444 4444444444 4444444444 4444444444 44444444414141 4141414141 4141414141 4141414141 41414141EI+

m/z240220200180160140120100806040

[x 1

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909090 9090909090 9090909090 9090909090 90909090868686 8686868686 8686868686 8686868686 86868686

777777 7777777777 7777777777 7777777777 77777777707070 7070707070 7070707070 7070707070 70707070

636363 6363636363 6363636363 6363636363 63636363565656 5656565656 5656565656 5656565656 56565656

444444 4444444444 4444444444 4444444444 44444444414141 4141414141 4141414141 4141414141 41414141

EI+

5-MeO-MiPTThe Drug Enforcement Administration's Special Testing and Research Laboratory

generated this monograph using structurally confirmed reference material.

Page 5 of 6SWGDRUG.org/monographs.htmLatest Revision: 5/27/2014

3.3 INFRARED SPECTROSCOPY (FTIR)

Insrument: FTIR with diamond ATR attachment (1 bounce)Scan Parameters: Number of scans: 32

Number of background scans: 32Resolution: 4 cm-1

Sample gain: 8Aperture: 150

FTIR ATR (Diamond, 1 Bounce): 5-MeO-MiPT; Lot SF1797

Wavenumber (cm-1)3500 3000 2500 2000 1500

%Tr

ansm

ittan

ce

40

48

56

64

72

3095309530953095309530953095309530953095309530953095309530953095309530953095309530953095 3037

303730373037303730373037303730373037303730373037303730373037303730373037303730373037

29702970297029702970297029702970297029702970297029702970297029702970297029702970297029702848284828482848284828482848284828482848284828482848284828482848284828482848284828482848 2831

283128312831283128312831283128312831283128312831283128312831283128312831283128312831

2794279427942794279427942794279427942794279427942794279427942794279427942794279427942794

2609260926092609260926092609260926092609260926092609260926092609260926092609260926092609

1624162416241624162416241624162416241624162416241624162416241624162416241624162416241624

1581158115811581158115811581158115811581158115811581158115811581158115811581158115811581

1475147514751475147514751475147514751475147514751475147514751475147514751475147514751475 1454

145414541454145414541454145414541454145414541454145414541454145414541454145414541454

1435143514351435143514351435143514351435143514351435143514351435143514351435143514351435

1360136013601360136013601360136013601360136013601360136013601360136013601360136013601360

1205120512051205120512051205120512051205120512051205120512051205120512051205120512051205

1065106510651065106510651065106510651065106510651065106510651065106510651065106510651065

966966966966966966966966966966966966966966966966966966966966966966

862862862862862862862862862862862862862862862862862862862862862862

796796796796796796796796796796796796796796796796796796796796796796

744744744744744744744744744744744744744744744744744744744744744744

696696696696696696696696696696696696696696696696696696696696696696 648

648648648648648648648648648648648648648648648648648648648648648

552552552552552552552552552552552552552552552552552552552552552552

498498498498498498498498498498498498498498498498498498498498498498 430

430430430430430430430430430430430430430430430430430430430430430

Wavenumber (cm-1)1700 1600 1500 1400 1300 1200 1100 1000 900 800 700

%Tr

ansm

ittan

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40

48

56

64

72

1624162416241624162416241624162416241624162416241624162416241624162416241624162416241624

1581158115811581158115811581158115811581158115811581158115811581158115811581158115811581

1497149714971497149714971497149714971497149714971497149714971497149714971497149714971497

1475147514751475147514751475147514751475147514751475147514751475147514751475147514751475 1454

145414541454145414541454145414541454145414541454145414541454145414541454145414541454

1435143514351435143514351435143514351435143514351435143514351435143514351435143514351435

1385138513851385138513851385138513851385138513851385138513851385138513851385138513851385

13601360136013601360136013601360136013601360136013601360136013601360136013601360136013601350135013501350135013501350135013501350135013501350135013501350135013501350135013501350

1321132113211321132113211321132113211321132113211321132113211321132113211321132113211321

1259125912591259125912591259125912591259125912591259125912591259125912591259125912591259 1236

123612361236123612361236123612361236123612361236123612361236123612361236123612361236 1205

120512051205120512051205120512051205120512051205120512051205120512051205120512051205

1167116711671167116711671167116711671167116711671167116711671167116711671167116711671167

1134113411341134113411341134113411341134113411341134113411341134113411341134113411341134

1115111511151115111511151115111511151115111511151115111511151115111511151115111511151115

1082108210821082108210821082108210821082108210821082108210821082108210821082108210821082

1065106510651065106510651065106510651065106510651065106510651065106510651065106510651065

1039103910391039103910391039103910391039103910391039103910391039103910391039103910391039

1028102810281028102810281028102810281028102810281028102810281028102810281028102810281028

966966966966966966966966966966966966966966966966966966966966966966

914914914914914914914914914914914914914914914914914914914914914914

877877877877877877877877877877877877877877877877877877877877877877

862862862862862862862862862862862862862862862862862862862862862862

818818818818818818818818818818818818818818818818818818818818818818

796796796796796796796796796796796796796796796796796796796796796796

779779779779779779779779779779779779779779779779779779779779779779

744744744744744744744744744744744744744744744744744744744744744744

696696696696696696696696696696696696696696696696696696696696696696 648

648648648648648648648648648648648648648648648648648648648648648

615615615615615615615615615615615615615615615615615615615615615615

584584584584584584584584584584584584584584584584584584584584584584

552552552552552552552552552552552552552552552552552552552552552552

525525525525525525525525525525525525525525525525525525525525525525

498498498498498498498498498498498498498498498498498498498498498498

447447447447447447447447447447447447447447447447447447447447447447

430430430430430430430430430430430430430430430430430430430430430430

5-MeO-MiPTThe Drug Enforcement Administration's Special Testing and Research Laboratory

generated this monograph using structurally confirmed reference material.

Page 6 of 6SWGDRUG.org/monographs.htmLatest Revision: 5/27/2014

http://en.wikipedia.org/wiki/5-MeO-MiPT

4. ADDITIONAL RESOURCES

Spratley, T.K.; Hays, P.A.; Geer, L.C.; Cooper, S.D.; McKibben, T.D. Analytical Profiles for Five"Designer" Tryptamines. Microgram Journal 2005, 3 (1-2), 54-68.

Wikipedia