13
MEDICAL POLICY – 7.01.564 Pulsed Radiofrequency Effective Date: Oct. 1, 2019 Last Revised: Sept. 5, 2019 Replaces: N/A RELATED MEDICAL POLICIES: 7.01.147 Ablation Procedures for Peripheral Neuromas 7.01.555 Facet Joint Denervation 7.01.565 Ablative Procedures of Peripheral Nerves to Treat Pain Select a hyperlink below to be directed to that section. POLICY CRITERIA | CODING | RELATED INFORMATION EVIDENCE REVIEW | REFERENCES | HISTORY Clicking this icon returns you to the hyperlinks menu above. Introduction Radiofrequency ablation is a way of destroying part of nerves to treat pain. An electrical current is produced by radio waves. The current is applied to a small area of nerve tissue, thus destroying (ablating) part of the nerve and interrupting pain signals. Pulsed radiofrequency is similar to radiofrequency ablation in that it is still being studied. Instead of a constant current being applied, pulsed radiofrequency calls for short bursts of energy. These intermittent bursts of energy allow more electrical current to be applied while keeping temperatures below the range that would ablate the nerve. Pulsed radiofrequency is investigational (unproven) to treat pain. More, larger, and longer studies are needed to see if this technique is safe and effective. Note: The Introduction section is for your general knowledge and is not to be taken as policy coverage criteria. The rest of the policy uses specific words and concepts familiar to medical professionals. It is intended for providers. A provider can be a person, such as a doctor, nurse, psychologist, or dentist. A provider also can be a place where medical care is given, like a hospital, clinic, or lab. This policy informs them about when a service may be covered. Policy Coverage Criteria

7.01.564 Pulsed Radiofrequency - Premera Blue CrossMEDICAL POLICY – 7.01.564 Pulsed Radiofrequency Effective Date: Oct. 1, 2019 Last Revised: Sept. 5, 2019 Replaces: N/A RELATED

  • Upload
    others

  • View
    4

  • Download
    0

Embed Size (px)

Citation preview

  • MEDICAL POLICY – 7.01.564

    Pulsed Radiofrequency

    Effective Date: Oct. 1, 2019

    Last Revised: Sept. 5, 2019

    Replaces: N/A

    RELATED MEDICAL POLICIES:

    7.01.147 Ablation Procedures for Peripheral Neuromas

    7.01.555 Facet Joint Denervation

    7.01.565 Ablative Procedures of Peripheral Nerves to Treat Pain

    Select a hyperlink below to be directed to that section.

    POLICY CRITERIA | CODING | RELATED INFORMATION

    EVIDENCE REVIEW | REFERENCES | HISTORY

    ∞ Clicking this icon returns you to the hyperlinks menu above.

    Introduction

    Radiofrequency ablation is a way of destroying part of nerves to treat pain. An electrical current

    is produced by radio waves. The current is applied to a small area of nerve tissue, thus

    destroying (ablating) part of the nerve and interrupting pain signals. Pulsed radiofrequency is

    similar to radiofrequency ablation in that it is still being studied. Instead of a constant current

    being applied, pulsed radiofrequency calls for short bursts of energy. These intermittent bursts

    of energy allow more electrical current to be applied while keeping temperatures below the

    range that would ablate the nerve. Pulsed radiofrequency is investigational (unproven) to treat

    pain. More, larger, and longer studies are needed to see if this technique is safe and effective.

    Note: The Introduction section is for your general knowledge and is not to be taken as policy coverage criteria. The

    rest of the policy uses specific words and concepts familiar to medical professionals. It is intended for

    providers. A provider can be a person, such as a doctor, nurse, psychologist, or dentist. A provider also can

    be a place where medical care is given, like a hospital, clinic, or lab. This policy informs them about when a

    service may be covered.

    Policy Coverage Criteria

    https://www.premera.com/medicalpolicies/7.01.147.pdfhttps://www.premera.com/medicalpolicies/7.01.555.pdfhttps://www.premera.com/medicalpolicies/7.01.565.pdf

  • Page | 2 of 11 ∞

    Procedure Investigational Pulsed radiofrequency Pulsed radiofrequency for the treatment of various chronic

    pain syndromes is considered investigational, including but

    not limited to the following:

    • Chronic facial and head pain (persistent idiopathic facial pain

    (PIFP)/spheno-palatine ganglion)

    • Coccydynia

    • Complex regional pain syndrome (reflex sympathetic

    dystrophy)

    • Diabetic peripheral neuropathy

    • Discogenic pain

    • Facet joint pain (cervical, lumbar, thoracic, sacro-iliac)/

    zygapophyseal joint pain

    • Headaches (eg, cervicogenic, migraines, cluster, tension)

    • Inguinal neuralgia

    • Intercostal neuralgia (post-surgical thoracic pain)

    • Low back pain

    • Lumbo-sacral radicular pain (eg, dorsal root ganglion)

    • Meralgia paresthetica (burning pain in the outer thigh related

    to lateral femoral cutaneous nerve entrapment)

    • Metacarpal or metatarsal joint pain of the hands and feet

    • Morton’s neuroma

    • Myofascial pain syndrome

    • Neck pain

    • Occipital neuralgia

    • Ophthalmic neuralgia

    • Orchialgia (testicular pain/spermatic cord)

    • Osteoarthritis of the knee or hip

    • Pelvic pain (eg, superior hypogastric plexus treatment for

    interstitial cystitis)

    • Peripheral neuromas

    • Piriformis syndrome (buttock pain and/or pain in the back of

    the lower extremity related to sciatic nerve irritation)

    • Plantar fasciitis

    • Post herpetic neuralgia (ophthalmic neuralgia)

    • Pudendal neuralgia

    • Sacro-iliac joint pain

    • Shoulder pain (suprascapular nerve)

  • Page | 3 of 11 ∞

    Procedure Investigational • Tarsal tunnel syndrome (compression neuropathy from

    entrapment of the posterior tibial nerve)

    • Trigeminal neuralgia

    • Vulvodynia

    Coding

    Code Description

    CPT 64999 Unlisted procedure, nervous system

    Note: CPT codes, descriptions and materials are copyrighted by the American Medical Association (AMA). HCPCS

    codes, descriptions and materials are copyrighted by Centers for Medicare Services (CMS).

    Related Information

    N/A

    Evidence Review

    Description

    Pulsed radiofrequency (PRF) is a non- or minimally neurodestructive technique, where short

    bursts of radiofrequency energy are applied to nervous tissue to treat various chronic pain

    syndromes. It is seen as an alternative to continuous (non-pulsed) radiofrequency ablation, as it

    is theorized to have significantly less complications or side effects. Its exact mechanism of action

    is unclear.

  • Page | 4 of 11 ∞

    Background

    Pulsed radiofrequency was first used in 1996 as a less destructive alternative to continuous (non-

    pulsed) radiofrequency. Pulsed radiofrequency is delivered in short bursts, twice per second,

    followed by a quiet phase in which no current is applied. This allows for cooling of the electrode

    keeping it below the neurodestructive threshold of 45° C. Pulsing the radiofrequency current

    allows the power output of the generator to be greatly increased, allowing for far stronger

    electrical fields than in continuous radiofrequency. For example, the voltage output is usually 15-

    25 volts for the continuous mode radiofrequency. The pulsed radiofrequency output is 45 volts.

    As a result, higher voltages can be applied in pulsed radiofrequency. Because the average

    temperature near the pulsed radiofrequency electrode does not reach the neurodestructive

    range, the risk of destroying nearby tissue is reduced.

    Pulsed radiofrequency has been used in the treatment of peripheral neuropathies, arthrogenic

    pain, painful trigger points, radiculopathy, and many other chronic pain syndromes. Unlike the

    known side effects of continuous radiofrequency such as, neuritis-like reactions, motor deficits,

    and the risk of deafferentation pain syndrome, pulsed radiofrequency seems to have few side

    effects and is seen as relatively safe. However, even though there is much anecdotal evidence

    which favors the use of pulsed radiofrequency for the use of pain relief without nervous tissue

    damage, especially in the treatment of neuropathic pain, there is a lack of randomized

    controlled trials (RCTs) substantiating its efficacy. The evidence is insufficient to determine the

    effects of the technology on health outcomes.

    Summary of Evidence

    For individuals with various chronic pain syndromes, especially neuropathic pain who received

    pulsed radiofrequency, the evidence includes a small number of RCTs, non-randomized

    controlled trials, prospective uncontrolled trials, retrospective studies, case series, and case

    reports. The majority of the uncontrolled and observational studies reported clinical efficacy of

    pulsed radiofrequency, however many of these studies had limitations. The controlled clinical

    data is limited and with inconsistent findings. Further research in the clinical and biological

    effects of pulsed radiofrequency is needed including well-designed, randomized controlled

    clinical trials with a large sample size and long-term follow-up to determine the therapeutic

    effect and safety of this treatment modality. There is also a lack of data comparing pulsed

    radiofrequency with conventional treatments. As such, it is unknown if pulsed radiofrequency

    offers any treatment advantage over other conventional treatments. The evidence is insufficient

    to determine the effects of the technology on health outcomes.

  • Page | 5 of 11 ∞

    Ongoing and Unpublished Clinical Trials

    Some currently unpublished trials that might influence this review are listed in Table 1.

    Table 1. Summary of Key Clinical Trials

    NCT No. Trial Name Planned

    Enrollment

    Completion

    Date

    Ongoing

    NCT03567590 The Efficacy and Safety of Sphenopalatine Ganglion

    Pulsed Radiofrequency Treatment for Cluster Headache

    80 May 2021

    NCT02915120 Ultrasound-Guided Pulsed Radiofrequency in the

    Treatment of Patients with Osteoarthritis Knee

    142 Dec 2020

    NCT03228316 Superior Hypogastric Plexus Block Versus Pulsed

    Radiofrequency for Chronic Pelvic Cancer Pain

    40 Not yet recruiting,

    Estimated start

    date Oct 2019

    NCT: national clinical trial

    Practice Guidelines and Position Statements

    American Society of Interventional Pain Physicians

    The American Society of Interventional Pain Physicians (ASIPP) published an updated guideline

    on interventional techniques in the management of chronic spinal pain Part II guidance and

    recommendation which states the following:

    • Lumbar spine

    o The evidence for therapeutic facet joint interventions is good for conventional

    radiofrequency, limited for pulsed radiofrequency, fair to good for lumbar facet joint

    nerve blocks, and limited for intraarticular injections

    o For sacroiliac interventions, the evidence for cooled radiofrequency neurotomy is fair;

    limited for intraarticular injections and periarticular injections; and limited for both

    pulsed radiofrequency and conventional radiofrequency neurotomy

    https://clinicaltrials.gov/ct2/show/NCT03567590?term=NCT03567590&rank=1https://clinicaltrials.gov/ct2/show/NCT02915120?term=NCT02915120&rank=1https://clinicaltrials.gov/ct2/show/NCT03228316?term=NCT03228316&rank=1

  • Page | 6 of 11 ∞

    • Cervical Spine

    o Evidence for therapeutic facet joint intervention is fair for conventional cervical

    radiofrequency neurotomy

    • Thoracic Spine

    o Evidence is limited for radiofrequency neurotomy

    Medicare National Coverage

    There is no national coverage determination.

    Regulatory Status

    A number of radiofrequency generators and probes have been cleared for marketing through

    the U.S. Food and Drug Administration (FDA) 510(k) process.

    References

    1. Abejon D, Garcia-del-Valle S, Fuentes ML, et al. Pulsed radiofrequency in lumbar radicular pain: Clinical effects in various

    etiological groups. Pain Pract. 2007;7(1):21-26.

    2. Ahadian FM. Pulsed radiofrequency neurotomy: Advances in pain medicine. Curr Pain Headache Rep. 2004;8(1):34-40.

    PMID:14731381.

    3. Akbas M, Gunduz E, Sanli S, Yegin A. Sphenopalatine ganglion pulsed radiofrequency treatment in patients suffering from

    chronic face and head pain. Rev Bras Anestesiol. 2016;66(1):50-54. PMID: 25467885.

    4. American Society of Interventional Pain Physicians (ASIPP). An Update of Comprehensive Evidence Based Guidelines for

    Interventional Techniques in Chronic Spinal Pain. Part II: Guidance and Recommendations. Pain Physicians 2013; 16:S49-

    S283PMID: 23615883..

    5. Basal S, Ergin A, Yildirim I, et al. A novel treatment of chronic orchialgia. J Androl. 2012;33(1):22-26.PMID: 21436311.

    6. Bayer E, Racz GB, Miles D, Heavner J. Sphenopalatine ganglion pulsed radiofrequency treatment in 30 patients suffering from

    chronic face and head pain. Pain Pract. 2005;5(3):223-227.

    7. •Bhatjiwale MG, Bhatjiwale MM, Bhagat A. Ultra-extended euthermic pulsed radiofrequency for the treatment of ophthalmic

    neuralgia: A case report with elaboration of a new technique. Surg Neurol Int. 2016;7(Suppl 35): S818-S823. PMID 27990312

    8. Bhatia A, Peng P, Cohen SP. Radiofrequency procedures to relieve chronic knee pain: An evidence-based narrative review. Reg

    Anesth Pain Med. 2016;41(4):501-510.PMID:27281721.

  • Page | 7 of 11 ∞

    9. Bui C, Pangarkar S, Zeitlin SI. Relief of urinary urgency, hesitancy, and male pelvic pain with pulse radiofrequency ablation of the

    pudendal nerve: A case presentation. Case Rep Urol. 2013;2013: 125703.PMID: 23607041.

    10. Byrd D, Mackey S. Pulsed radiofrequency for chronic pain. Curr Pain Headache Rep. 2008;12(1):37-4.PMID:18417022.

    11. Cahana A, Van Zundert J, Macrea L, et al. Pulsed radiofrequency: Current clinical and biological literature available. Pain Med.

    2006;7(5):411-423. PMID:17014600.

    12. Chen Y, Huang-Lionnet JHY, Cohen SP. Radiofrequency ablation in coccydynia: A case series and comprehensive, evidence-

    based review. Pain Med. 2017;18(6):1111-1130. PMID:28034983.

    13. Cho IT, Cho YW, Kwak SG, Chang MC. Comparison between ultrasound-guided interfascial pulsed radiofrequency and

    ultrasound-guided interfascial block with local anesthetic in myofascial pain syndrome of trapezius muscle. Medicine

    (Baltimore). 2017;96(5): e6019. PMID:28151904.

    14. Choi GS, Ahn SH, Cho YW et al. Short-term effects of pulsed radiofrequency on chronic refractory cervical radicular pain. Ann

    Rehabil Med. 2011 Dec;35(6):826-32. PMID:22506211.

    15. Choi HJ, Oh IH, Choi SK, Lim YJ. Clinical outcomes of pulsed radiofrequency neuromodulation for the treatment of occipital

    neuralgia. J Korean Neurosurg Soc. 2012;51(5):281-285. PMID:22792425.

    16. Chon JY, Hahn YJ, Sung CH, et al. Pulsed radiofrequency under ultrasound guidance for the tarsal tunnel syndrome: Two case

    reports. J Anesth. 2014;28(6):924-927.PMID:24728720.

    17. Chua NH, Vissers KC, Sluijter ME. Pulsed radiofrequency treatment in interventional pain management: Mechanisms and

    potential indications-a review. Acta Neurochir (Wien). 2011;153(4):763-771.PMID:21116663.

    18. Cohen SP, Sireci A, Wu CL, et al. Pulsed radiofrequency of the dorsal root ganglia is superior to pharmacotherapy or pulsed

    radiofrequency of the intercostal nerves in the treatment of chronic postsurgical thoracic pain. Pain Physician. 2006;9(3):227-

    235.PMID:16886031.

    19. De Andres J, Sanchis-Lopez N, Asensio-Samper JM, et al. Vulvodynia -- An evidence-based literature review and proposed

    treatment algorithm. Pain Pract. 2016;16(2):204-236.PMID:25581081.

    20. Deniz S, Purtuloglu T, Tekindur S, et al. Ultrasound-guided pulsed radiofrequency treatment in Morton's neuroma. J Am Podiatr

    Med Assoc. 2015;105(4):302-306.PMID:25945935.

    21. Ding DF, Li RC, Xiong QJ, et al. Pulsed radiofrequency to the great occipital nerve for the treatment of intractable postherpetic

    itch: A case report. Int J Clin Exp Med. 2014;7(10):3497-3500. PMID 25419389

    22. Erdine S, Ozyalcin NS, Cimen A, et al. Comparison of pulsed radiofrequency with conventional radiofrequency in the treatment

    of idiopathic trigeminal neuralgia. Eur J Pain. 2007;11(3):309-313.PMID:16762570.

    23. Eyigor C, Eyigor S, Akdeniz S, Uyar M. Effects of intra-articular application of pulsed radiofrequency on pain, functioning and

    quality of life in patients with advanced knee osteoarthritis. J Back Musculoskelet Rehabil. 2015;28(1):129-134.PMID:25061031.

    24. Facchini G, Spinnato P, Guglielmi G, et al. A comprehensive review of pulsed radiofrequency in the treatment of pain associated

    with different spinal conditions. Br J Radiol. 2017;90(1073): 20150406.PMID:28186832.

    25. Fang L, Ying S, Tao W, et al. 3D CT-guided pulsed radiofrequency treatment for trigeminal neuralgia. Pain Pract. 2014;14(1):16-

    21. PMID :23433058.

    26. Forouzanfar T, van Kleef M, Weber WE. Radiofrequency lesions of the stellate ganglion in chronic pain syndromes:

    Retrospective analysis of clinical efficacy in 86 patients. Clin J Pain. 2000;16(2):164-168.PMID:10870729.

    27. Gallagher RM. Pulsed radiofrequency treatment: What is the evidence of its effectiveness and should it be used in clinical

    practice? Pain Med. 2006;7(5):408-410.PMID:17014599.

    28. Gofeld M, Restrepo-Garces CE, Theodore BR et al. Pulsed radiofrequency of suprascapular nerve for chronic shoulder pain: a

    randomized double-blind active placebo-controlled study. Pain Pract. 2013;13(2):96-103. PMID:22554345.

    29. Grandhi RK, Kaye AD, Abd-Elsayed A. Systematic review of radiofrequency ablation and pulsed radiofrequency for management

    of cervicogenic headaches. Curr Pain Headache Rep. 2018;22(3):18. PMID: 29476360.

  • Page | 8 of 11 ∞

    30. Guo J, Dong X, Zhao X. Treatment of trigeminal neuralgia by radiofrequency of the Gasserian ganglion. Rev Neurosci.

    2016;27(7):739-743.PMID:27383870.

    31. Guo L, Kubat NJ, Nelson TR et al. Meta-analysis of clinical efficacy of pulsed radiofrequency energy treatment. Ann Surg. 2012

    Mar; 255(3):457-67 PMID: 22301609.

    32. Gupta A, Huettner DP, Dukewich M. Comparative effectiveness review of cooled Versus pulsed radiofrequency ablation for the

    treatment of knee osteoarthritis: A systematic review. Pain Physician. 2017;20(3):155-171.PMID:28339430.

    33. Hansen H, Manchikanti L, Simopoulos TT, et al. A systematic evaluation of the therapeutic effectiveness of sacroiliac joint

    interventions. Pain Physician. 2012;15(3): E247-E278. PMID:22622913.

    34. Hetta DF, Mahran AM, Kamal EE. Pulsed radiofrequency treatment for chronic post-surgical orchialgia: A double-blind, sham-

    controlled, randomized trial: Three-month results. Pain Physician. 2018;21(2):199-205. PMID: 29565950.

    35. Ke M, Yinghui F, Yi J, et al. Efficacy of pulsed radiofrequency in the treatment of thoracic postherpetic neuralgia from the

    angulus costae: A randomized, double-blinded, controlled trial. Pain Physician. 2013;16(1):15-25. PMID :23340530.

    36. Kesikburun S, Yaşar E, Uran A, et al. Ultrasound-guided genicular nerve pulsed radiofrequency treatment for painful knee

    osteoarthritis: A preliminary report. Pain Physician. 2016;19(5 :E751-E759.PMID:27389118.

    37. Kestranek J, Spacek J, Ryska P, et al. Radiofrequency therapy for severe idiopathic vulvodynia. J Low Genit Tract Dis.

    2013;17(4):e1-e4.PMID:23903198.

    38. Kim JH, Kim E, Kim BI. Pulsed radiofrequency treatment of the superior hypogastric plexus in an interstitial cystitis patient with

    chronic pain and symptoms refractory to oral and intravesical medications and bladder hydrodistension: A case report.

    Medicine (Baltimore). 2016;95(49): e5549.PMID:27930554.

    39. Kim YK, Jung I, Lee CH, et al. Pulsed radiofrequency ablation under ultrasound guidance for huge neuroma. Korean J Pain.

    2014;27(3):290-293.PMID:25031817.

    40. Lee JJ, Sohn JH, Choi HJ, et al. Clinical efficacy of pulsed radiofrequency neuromodulation for intractable meralgia paresthetica.

    Pain Physician. 2016;19(3):173-179.PMID:27008291.

    41. Lindner R, Sluijter ME, Schleinzer W. Pulsed radiofrequency treatment of the lumbar medial branch for facet pain: A

    retrospective analysis. Pain Med. 2006;7(5):435-439.PMID:17014603.

    42. Lopez BC, Hamlyn PJ, Zakrzewska JM. Systematic review of ablative neurosurgical techniques for the treatment of trigeminal

    neuralgia. Neurosurgery. 2004;54(4):973-982; discussion 982-983.PMID:12823880.

    43. Luleci N, Ozdemir U, Dere K et al. Evaluation of patients’ response to pulsed radiofrequency treatment applied to the

    suprascapular nerve in patients with chronic shoulder pain. J Back Musculoskelet Rehabil. 2011;24(3):189-94. PMID :21849733.

    44. Makharita MY, Amr YM. Pulsed radiofrequency for chronic inguinal neuralgia. Pain Physician. 2015;18(2): E147-

    E155.PMID:25794213.

    45. Malik K, Benzon HT. Pulsed radiofrequency: A critical review of its efficacy. Anaesth Intensive Care. 2007;35(6):863-

    873.PMID:18084976.

    46. Malik K, Benzon HT. Radiofrequency applications to dorsal root ganglia: A literature review. Anesthesiology. 2008;109(3):527-

    542.PMID:18719452

    47. Manchikanti L, Abdi S, Atluri S, et al. An update of comprehensive evidence-based guidelines for interventional techniques in

    chronic spinal pain. Part II: Guidance and recommendations. Pain Physician. 2013;16(2 Suppl):S49-S283.PMID:23615883.

    48. Manchikanti L. The role of radiofrequency in the management of complex regional pain syndrome. Curr Rev Pain.

    2000;4(6):437-444.PMID:11060589.

    49. Manolitsis N, Elahi F. Pulsed radiofrequency for occipital neuralgia. Pain Physician 2014; 17(6): E709-E717. PMID:25415786.

    50. Martin DC, Willis ML, Mullinax LA, et al. Pulsed radiofrequency application in the treatment of chronic pain. Pain Pract.

    2007;7(1):31-35PMID:17305676.

  • Page | 9 of 11 ∞

    51. Mikeladze G, Espinal R, Finnegan R, et al. Pulsed radiofrequency application in treatment of chronic zygapophyseal joint pain.

    Spine J. 2003;3(5):360-362.PMID:14588947.

    52. Misra S, Ward S, Coker C. Pulsed radiofrequency for chronic testicular pain-a preliminary report. Pain Med. 2009;10(4):673-678.

    PMID:19302438.

    53. Naderi Nabi B, Sedighinejad A, Haghighi M, et al. Comparison of transcutaneous electrical nerve stimulation and pulsed

    radiofrequency sympathectomy for treating painful diabetic neuropathy. Anesth Pain Med. 2015;5(5) :e29280.PMID:26587405.

    54. Nagar VR, Birthi P, Grider JS, Asopa A. Systematic review of radiofrequency ablation and pulsed radiofrequency for

    management of cervicogenic headache. Pain Physician. 2015;18(2):109-130. PMID:25794199.

    55. Nagda JV, Davis CW, Bajwa ZH et al. Retrospective review of the efficacy and safety of repeated pulsed and continuous

    radiofrequency lesioning of the dorsal root ganglion/segmental nerve for lumbar radicular pain. Pain Physician. 2011;14(4):371-

    6.

    56. Navani A, Mahajan G, Kreis P, Fishman SM. A case of pulsed radiofrequency lesioning for occipital neuralgia. Pain Med.

    2006;7(5):453-456. PMID:17014606.

    57. Osman AM, El-Hammady DH, Kotb MM. Pulsed compared to thermal radiofrequency to the medial calcaneal nerve for

    management of chronic refractory plantar fasciitis: A prospective comparative study. Pain Physician. 2016;19(8): E1181-

    E1187.PMID: 27906949.

    58. Park HG, Park PG, Kim WJ, et al. Ultrasound-assisted mental nerve block and pulsed radiofrequency treatment for intractable

    postherpetic neuralgia: Three case studies. Korean J Pain. 2014;27(1):81-85. PMID: 24478907.

    59. Park SM, Cho YW, Ahn SH, et al. Comparison of the effects of ultrasound-guided interfascial pulsed radiofrequency and

    ultrasound-guided interfascial injection on myofascial pain syndrome of the gastrocnemius. Ann Rehabil Med. 2016;40(5):885-

    892. PMID: 27847719.

    60. Picelli A, Lobba D, Vendramin P, et al. A retrospective case series of ultrasound-guided suprascapular nerve pulsed

    radiofrequency treatment for hemiplegic shoulder pain in patients with chronic stroke. J Pain Res. 2018;11: 1115-1120. PMID:

    29942146.

    61. Rhame EE, Levey KA, Gharibo CG. Successful treatment of refractory pudendal neuralgia with pulsed radiofrequency. Pain

    Physician. 2009;12(3):633-638.PMID: 19461829.

    62. Schianchi PM, Sluijter ME, Balogh SE. The treatment of joint pain with intra-articular pulsed radiofrequency. Anesth Pain Med.

    2013;3(2):250-255.

    63. Schianchi PM. A new technique to treat facet joint pain with pulsed radiofrequency. Anesth Pain Med. 2015;5(1): e21061.

    64. Shah RV, Racz GB. Long-term relief of posttraumatic headache by sphenopalatine ganglion pulsed radiofrequency lesioning: A

    case report. Arch Phys Med Rehabil. 2004;85(6):1013-1016.PMID:15179659.

    65. Shanthanna H, Chan P, McChesney J, et. al. Pulsed radiofrequency treatment of the lumbar dorsal root ganglion in patients with

    chronic lumbar radicular pain: a randomized, placebo-controlled pilot study. J Pain Res 2014:7 47-55. PMID:24453500.

    66. Simopoulos TT, Kraemer J, Nagda JV, et al. Response to pulsed and continuous radiofrequency lesioning of the dorsal root

    ganglion and segmental nerves in patients with chronic lumbar radicular pain. Pain Physician. 2008;11(2):137-

    144.PMID:18354708.

    67. Tamimi MA, McCeney MH, Krutsch J. A case series of pulsed radiofrequency treatment of myofascial trigger points and scar

    neuromas. Pain Med. 2009;10(6):1140-1143.PMID:19594852.

    68. Taverner MG, Loughnan TE, Soon CW, et al. Transcutaneous application of pulsed radiofrequency treatment for shoulder pain.

    Pain Pract. 2013;13(4):310-315.PMID:22863196.

    69. Taverner MG, Ward TL, Loughnan TE. Transcutaneous pulsed radiofrequency treatment in patients with painful knee awaiting

    total knee joint replacement. Clin J Pain. 2010;26(5):429-432.PMID:20473051.

  • Page | 10 of 11 ∞

    70. Teixeira A, Sluijter ME. Intradiscal high-voltage, long-duration pulsed radiofrequency for discogenic pain: A preliminary report.

    Pain Med. 2006;7(5):424-428.PMID:17014601.

    71. Tekin I, Mirzai H, Ok G et al. A comparison of conventional and pulsed radiofrequency denervation in the treatment of chronic

    facet joint pain. Clin J Pain. 2007 23(6):524-529.PMID:17575493.

    72. Tella P, Stojanovic M. Novel therapies for chronic cervical radicular pain: Does pulsed radiofrequency have a role? Expert Rev

    Neurother. 2007;7(5):471-472.PMID:17492898.

    73. Terkawi AS, Romdhane K. Ultrasound-guided pulsed radiofrequency ablation of the genital branch of the genitofemoral nerve

    for treatment of intractable orchalgia. Saudi J Anaesth. 2014;8(2):294-298.PMID:24843352.

    74. Thapa D, Ahuja V. Combination of diagnostic medial calcaneal nerve block followed by pulsed radiofrequency for plantar

    fascitis pain: A new modality. Indian J Anaesth. 2014;58(2):183-185.PMID:24963184.

    75. Todorov L. Pulsed radiofrequency of the sural nerve for the treatment of chronic ankle pain. Pain Physician. 2011;14(3):301-4.

    PMID: 21587334.

    76. Vallejo R, Benyamin RM, Kramer J, et al. Pulsed radiofrequency denervation for the treatment of sacroiliac joint syndrome. Pain

    Med. 2006;7(5):429-434.PMID:17014602.

    77. Van Boxem K, van Bilsen J, de Meij N, et al. Pulsed radiofrequency treatment adjacent to the lumbar dorsal root ganglion for

    the management of lumbosacral radicular syndrome: A clinical audit. Pain Med. 2011;12(9):1322-1330.PMID:21812907.

    78. Van Boxem K, van Eerd M, Brinkhuizen T, et al. Radiofrequency and pulsed radiofrequency treatment of chronic pain

    syndromes: The available evidence. Pain Pract. 2008;8(5):385-393.PMID:18721175.

    79. Van Zundert J, Brabant S, Van de Kelft E, et al. Pulsed radiofrequency treatment of the gasserian ganglion in patients with

    idiopathic trigeminal neuralgia. Pain. 2003;104(3):449-452.PMID:12927617.

    80. Van Zundert J, Patijn J, Kessels A, et al. Pulsed radiofrequency adjacent to the cervical dorsal root ganglion in chronic cervical

    radicular pain: A double blind sham controlled randomized clinical trial. Pain. 2007;127(1-2):173-182.PMID:17055165.

    81. Vanderhoek, MD. Hoang HT, Goff B, Ultrasound guided greater occipital nerve blocks and pulsed radiofrequency ablation for

    diagnosis and treatment of occipital neuralgia. Anesth Pain Med 2013;3(2):256-9. PMID:24282778

    82. Vanelderen P, Rouwette T, De Vooght P, et al. Pulsed radiofrequency for the treatment of occipital neuralgia: A prospective

    study with 6 months of follow-up. Reg Anesth Pain Med. 2010;35(2):148-151.PMID:20301822.

    83. Weiss AL, Ehrhardt KP, Tolba R. Atypical facial pain: A comprehensive, evidence-based review. Curr Pain Headache Rep.

    2017;21(2):8PMID:28251523.

    84. Werner MU, Bischoff JM, Rathmell JP, Kehlet H. Pulsed radiofrequency in the treatment of persistent pain after inguinal

    herniotomy: A systematic review. Reg Anesth Pain Med. 2012;37(3):340-343.PMID:22476237.

    85. Whitworth LA, Feler CA. Application of spinal ablative techniques for the treatment of benign chronic painful conditions:

    History, methods, and outcomes. Spine. 2002;27(22):2607-2612; discussion 2613.PMID:12436001.

    86. Zakrzewska JM, Akram H. Neurosurgical interventions for the treatment of classical trigeminal neuralgia. Cochrane Database

    Syst Rev. 2011;(9):CD007312.PMID:21901707.

    87. Zhang J, Shi DS, Wang R. Pulsed radiofrequency of the second cervical ganglion (C2) for the treatment of cervicogenic

    headache. J Headache Pain. 2011 12(5):569-71. PMID:216118080..

    History

  • Page | 11 of 11 ∞

    Date Comments 09/01/18 New policy, approved August 14, 2018, effective December 6, 2018. Add to Surgery

    section. Policy created with a literature review through July 2018. Pulsed

    radiofrequency for the treatment of various chronic pain syndromes is considered

    investigational.

    10/01/19 Annual Review, approved September 5, 2019. Policy updated with literature review.

    References added. Policy statement unchanged.

    Disclaimer: This medical policy is a guide in evaluating the medical necessity of a particular service or treatment. The

    Company adopts policies after careful review of published peer-reviewed scientific literature, national guidelines and

    local standards of practice. Since medical technology is constantly changing, the Company reserves the right to review

    and update policies as appropriate. Member contracts differ in their benefits. Always consult the member benefit

    booklet or contact a member service representative to determine coverage for a specific medical service or supply.

    CPT codes, descriptions and materials are copyrighted by the American Medical Association (AMA). ©2019 Premera

    All Rights Reserved.

    Scope: Medical policies are systematically developed guidelines that serve as a resource for Company staff when

    determining coverage for specific medical procedures, drugs or devices. Coverage for medical services is subject to

    the limits and conditions of the member benefit plan. Members and their providers should consult the member

    benefit booklet or contact a customer service representative to determine whether there are any benefit limitations

    applicable to this service or supply. This medical policy does not apply to Medicare Advantage.

  • Discrimination is Against the Law

    Premera Blue Cross complies with applicable Federal civil rights laws and does not discriminate on the basis of race, color, national origin, age, disability, or sex. Premera does not exclude people or treat them differently because of race, color, national origin, age, disability or sex.

    Premera: • Provides free aids and services to people with disabilities to communicate

    effectively with us, such as: • Qualified sign language interpreters • Written information in other formats (large print, audio, accessible

    electronic formats, other formats) • Provides free language services to people whose primary language is not

    English, such as: • Qualified interpreters• Information written in other languages

    If you need these services, contact the Civil Rights Coordinator.

    If you believe that Premera has failed to provide these services or discriminated in another way on the basis of race, color, national origin, age, disability, or sex, you can file a grievance with: Civil Rights Coordinator - Complaints and Appeals PO Box 91102, Seattle, WA 98111 Toll free 855-332-4535, Fax 425-918-5592, TTY 800-842-5357 Email [email protected]

    You can file a grievance in person or by mail, fax, or email. If you need help filing a grievance, the Civil Rights Coordinator is available to help you.

    You can also file a civil rights complaint with the U.S. Department of Health and Human Services, Office for Civil Rights, electronically through the Office for Civil Rights Complaint Portal, available at https://ocrportal.hhs.gov/ocr/portal/lobby.jsf, or by mail or phone at: U.S. Department of Health and Human Services 200 Independence Avenue SW, Room 509F, HHH Building Washington, D.C. 20201, 1-800-368-1019, 800-537-7697 (TDD) Complaint forms are available at http://www.hhs.gov/ocr/office/file/index.html.

    Getting Help in Other Languages

    This Notice has Important Information. This notice may have important information about your application or coverage through Premera Blue Cross. There may be key dates in this notice. You may need to take action by certain deadlines to keep your health coverage or help with costs. You have the right to get this information and help in your language at no cost. Call 800-722-1471 (TTY: 800-842-5357).

    አማሪኛ (Amharic): ይህ ማስታወቂያ አስፈላጊ መረጃ ይዟል። ይህ ማስታወቂያ ስለ ማመልከቻዎ ወይም የ Premera Blue Cross ሽፋን አስፈላጊ መረጃ ሊኖረው ይችላል። በዚህ ማስታወቂያ ውስጥ ቁልፍ ቀኖች ሊኖሩ ይችላሉ። የጤናን ሽፋንዎን ለመጠበቅና በአከፋፈል እርዳታ ለማግኘት በተውሰኑ የጊዜ ገደቦች እርምጃ መውሰድ ይገባዎት ይሆናል። ይህን መረጃ እንዲያገኙ እና ያለምንም ክፍያ በቋንቋዎ እርዳታ እንዲያገኙ መብት አለዎት።በስልክ ቁጥር 800-722-1471 (TTY: 800-842-5357) ይደውሉ።

    ( ةالعربي :(. امةھ ماتولعم اإلشعار ھذا يحوي

    خالل من ھاعلي صولحلا تريد لتيا التغطيةلل أو ةصحيلاكطيتتغ لىع اظلحفل نةعيم يخراوت في إجراء خاذتال تحتاج وقد .اإلشعار ھذا في

    تكلفة أية بدتك دون بلغتك مساعدةوال تاوملالمع ھذه على ولحصال لك يحق .800-722-1471 (TTY: 800-842-5357)

    أو طلبك وصخصب مةمھ ماتوعلم عارشإلا ھذا ويحي قدةمھم يخراوت ھناك تكون قد .Premera Blue Cross

    اعدةمس تصلايفكالتال دفع فيبـ

    .

    Arabic

    Oromoo (Cushite): Beeksisni kun odeeffannoo barbaachisaa qaba. Beeksisti kun sagantaa yookan karaa Premera Blue Cross tiin tajaajila keessan ilaalchisee odeeffannoo barbaachisaa qabaachuu danda’a. Guyyaawwan murteessaa ta’an beeksisa kana keessatti ilaalaa. Tarii kaffaltiidhaan deeggaramuuf yookan tajaajila fayyaa keessaniif guyyaa dhumaa irratti wanti raawwattan jiraachuu danda’a. Kaffaltii irraa bilisa haala ta’een afaan keessaniin odeeffannoo argachuu fi deeggarsa argachuuf mirga ni qabaattu. Lakkoofsa bilbilaa 800-722-1471 (TTY: 800-842-5357) tii bilbilaa.

    Français (French): Cet avis a d'importantes informations. Cet avis peut avoir d'importantes informations sur votre demande ou la couverture par l'intermédiaire de Premera Blue Cross. Le présent avis peut contenir des dates clés. Vous devrez peut-être prendre des mesures par certains délais pour maintenir votre couverture de santé ou d'aide avec les coûts. Vous avez le droit d'obtenir cette information et de l’aide dans votre langue à aucun coût. Appelez le 800-722-1471 (TTY: 800-842-5357).

    Kreyòl ayisyen (Creole): Avi sila a gen Enfòmasyon Enpòtan ladann. Avi sila a kapab genyen enfòmasyon enpòtan konsènan aplikasyon w lan oswa konsènan kouvèti asirans lan atravè Premera Blue Cross. Kapab genyen dat ki enpòtan nan avi sila a. Ou ka gen pou pran kèk aksyon avan sèten dat limit pou ka kenbe kouvèti asirans sante w la oswa pou yo ka ede w avèk depans yo. Se dwa w pou resevwa enfòmasyon sa a ak asistans nan lang ou pale a, san ou pa gen pou peye pou sa. Rele nan 800-722-1471 (TTY: 800-842-5357).

    Deutsche (German): Diese Benachrichtigung enthält wichtige Informationen. Diese Benachrichtigung enthält unter Umständen wichtige Informationen bezüglich Ihres Antrags auf Krankenversicherungsschutz durch Premera Blue Cross. Suchen Sie nach eventuellen wichtigen Terminen in dieser Benachrichtigung. Sie könnten bis zu bestimmten Stichtagen handeln müssen, um Ihren Krankenversicherungsschutz oder Hilfe mit den Kosten zu behalten. Sie haben das Recht, kostenlose Hilfe und Informationen in Ihrer Sprache zu erhalten. Rufen Sie an unter 800-722-1471 (TTY: 800-842-5357).

    Hmoob (Hmong): Tsab ntawv tshaj xo no muaj cov ntshiab lus tseem ceeb. Tej zaum tsab ntawv tshaj xo no muaj cov ntsiab lus tseem ceeb txog koj daim ntawv thov kev pab los yog koj qhov kev pab cuam los ntawm Premera Blue Cross. Tej zaum muaj cov hnub tseem ceeb uas sau rau hauv daim ntawv no. Tej zaum koj kuj yuav tau ua qee yam uas peb kom koj ua tsis pub dhau cov caij nyoog uas teev tseg rau hauv daim ntawv no mas koj thiaj yuav tau txais kev pab cuam kho mob los yog kev pab them tej nqi kho mob ntawd. Koj muaj cai kom lawv muab cov ntshiab lus no uas tau muab sau ua koj hom lus pub dawb rau koj. Hu rau 800-722-1471 (TTY: 800-842-5357).

    Iloko (Ilocano): Daytoy a Pakdaar ket naglaon iti Napateg nga Impormasion. Daytoy a pakdaar mabalin nga adda ket naglaon iti napateg nga impormasion maipanggep iti apliksayonyo wenno coverage babaen iti Premera Blue Cross. Daytoy ket mabalin dagiti importante a petsa iti daytoy a pakdaar. Mabalin nga adda rumbeng nga aramidenyo nga addang sakbay dagiti partikular a naituding nga aldaw tapno mapagtalinaedyo ti coverage ti salun-atyo wenno tulong kadagiti gastos. Adda karbenganyo a mangala iti daytoy nga impormasion ken tulong iti bukodyo a pagsasao nga awan ti bayadanyo. Tumawag iti numero nga 800-722-1471 (TTY: 800-842-5357).

    Italiano ( ):Questo avviso contiene informazioni importanti. Questo avviso può contenere informazioni importanti sulla tua domanda o copertura attraverso Premera Blue Cross. Potrebbero esserci date chiave in questo avviso. Potrebbe essere necessario un tuo intervento entro una scadenza determinata per consentirti di mantenere la tua copertura o sovvenzione. Hai il diritto di ottenere queste informazioni e assistenza nella tua lingua gratuitamente. Chiama 800-722-1471 (TTY: 800-842-5357).

    Italian

    中文 (Chinese):本通知有重要的訊息。本通知可能有關於您透過 Premera Blue Cross 提交的申請或保險的重要訊息。本通知內可能有重要日期。您可能需要在截止日期

    之前採取行動,以保留您的健康保險或者費用補貼。您有權利免費以您的母

    語得到本訊息和幫助。請撥電話 800-722-1471 (TTY: 800-842-5357)。

    037338 (07-2016)

    https://www.hhs.gov/ocr/office/file/index.htmlhttps://ocrportal.hhs.gov/ocr/portal/lobby.jsfmailto:[email protected]

  • 日本語 (Japanese):この通知には重要な情報が含まれています。この通知には、 Premera Blue Crossの申請または補償範囲に関する重要な情報が含まれている場合があります。この通知に記載されている可能性がある重要な日付をご確認くだ

    さい。健康保険や有料サポートを維持するには、特定の期日までに行動を

    取らなければならない場合があります。ご希望の言語による情報とサポー

    トが無料で提供されます。800-722-1471 (TTY: 800-842-5357)までお電話ください。

    한국어 (Korean): 본 통지서에는 중요한 정보가 들어 있습니다 . 즉 이 통지서는 귀하의 신청에 관하여 그리고 Premera Blue Cross 를 통한 커버리지에 관한 정보를 포함하고 있을 수 있습니다 . 본 통지서에는 핵심이 되는 날짜들이 있을 수 있습니다. 귀하는 귀하의 건강 커버리지를 계속 유지하거나 비용을 절감하기 위해서 일정한 마감일까지 조치를 취해야 할 필요가 있을 수 있습니다 . 귀하는 이러한 정보와 도움을 귀하의 언어로 비용 부담없이 얻을 수 있는 권리가 있습니다 . 800-722-1471 (TTY: 800-842-5357) 로 전화하십시오 .

    ລາວ (Lao): ແຈ້ງການນີ້ ນສໍ າຄັນ. ແຈ້ງການນີ້ອາດຈະມີ ນສໍ າຄັນກ່ຽວກັບຄໍ າຮ້ອງສະ ກ ຫຼື ຄວາມຄຸ້ມຄອງປະກັນໄພຂອງທ່ານຜ່ານ Premera Blue Cross. ອາດຈະມີ ນທີ າຄັນໃນແຈ້ງການນີ້. ທ່ານອາດຈະຈໍ າເປັ ນຕ້ອງດໍ າເນີ ນການຕາມກໍ ານົດ ເວລາສະເພາະເພື່ອຮັກສາຄວາມຄຸ້ມຄອງປະກັນສຸຂະພາບ ຫຼື ຄວາມຊ່ວຍເຫຼື ອເລື່ອງ າໃຊ້ າຍຂອງທ່ານໄວ້ . ທ່ານມີ ດໄດ້ ບຂໍ້ ນນີ້ ແລະ ຄວາມຊ່ວຍເຫຼື ອເປັ ນພາສາ ຂອງທ່ານໂດຍບ່ໍ ເສຍຄ່າ. ໃຫ້ໂທຫາ 800-722-1471 (TTY: 800-842-5357).

    ູຂໍ້

    ສໍ ັ

    ສິ

    ມູຮັ

    ູມີ ມຂໍ້

    ភាសាែខមរ ( ): ឹ

    រងរបស់

    Premera Blue Cross ។ របែហលជាមាន កាលបរ ិ ឆ ំខានេនៅកងេសចក

    េសចកតជី ូ

    ជាមានព័ ៌ ៉ ងសំ ់អពី ់ ៉ ប់

    នដំ ងេនះមានព័ ី

    តមានយា ខាន ំ ទរមងែបបបទ ឬការរា

    ណ ត៌មានយ៉ា ំ ់ តងសខាន។ េសចក

    េចទស ់ ន ុ ត

    ណងេនះ។ អ វការបេញញសមតភាព ដលកណតៃថ ចបាស

    កតាមរយៈ

    ដំ ឹ នករបែហលជារតូ ច ថ ់ ំ ់ ងជាក់ ់

    នដ

    ី ន

    ំណឹងេនះរបែហល

    នានា េដើ ីនងរកសាទុ ៉ បរងស់ ុ ់ ក ឬរបាក់ ំ

    មប ឹ កការធានារា ខភាពរបស ជ

    ធនកមានសិ ទទលព័ មានេនះ និ ំ យេនៅកុងភាសារបសទិ ួ ត៌ ងជ ននួ

    ់ កេដាយម

    នអ

    យេចញៃថល។ ួ

    នអស

    លុ ើ ូ ូយេឡយ។ សមទ ទ រស័ព 800-722-1471 (TTY: 800-842-5357)។

    Khmer

    ਕਵਰਜ ਅਤ ਅਰਜੀ ਬਾਰ ਮਹ ਤਵਪਰਨ ਜਾਣਕਾਰੀ ਹ ਸਕਦੀ ਹ . ਇਸ ਨ ਿਜਸ ਜਵਚ ਖਾਸ

    ਤਾਰੀਖਾ ਹ ਸਕਦੀਆ ਹਨ. ਜੇਕਰ ਤਸੀ ਜਸਹਤ ਕਵਰਜ ਿਰਖਣੀ ਹਵ ਜਾ ਓਸ ਦੀ ਲਾਗਤ ਜਿਵਚ ਮਦਦ ਦ ੇਇਛ ੁਕ ਹ ਤਾਂ ਤਹਾਨ ਅ ਤਮ ਤਾਰੀਖ਼ ਤ ਪਿਹਲਾਂ ਕੁ ਝ ਖਾਸ ਕਦਮ ਚ ਕਣ ਦੀ ਲੜ ਹ ਸਕਦੀ ਹ ,ਤਹੁਾਨ ਮਫ਼ਤ ਿਵਚ ਤ ਆਪਣੀ ਭਾਸ਼ਾ ਿਵ ਚ ਜਾਣਕਾਰੀ ਅਤ ਮਦਦ ਪਾਪਤ ਕਰਨ ਦਾ ਅਿਧਕਾਰ ਹ ,ਕਾਲ 800-722-1471 (TTY: 800-842-5357).

    ਪ ਜਾਬੀ (Punjabi): ਇਸ ਨ ਿਟਸ ਿਵਚ ਖਾਸ ਜਾਣਕਾਰੀ ਹ. ਇਸ ਨ ਿਟਸ ਿਵਚ Premera Blue Cross ਵਲ ਤੁਹਾਡੀ

    ੇ ੇ ੇ ੱ ੂ ੋ ੈ ੋੋ ਂ ੁ ੇ ੱ ੋ ੇ ੱੱ ੁ ੱ ੂੁ ੱ ੇ ੱ ੇ ੍ਰ ੈ

    ੋ ੰ ੂ ੱ ੁ ੋ ੋ ੈ ੰ

    ੋ ੈ ੋ

    (Farsi): فارسی فرم بارهدر ھمم اطالعات حاوی است ممکن يهمالعا اين. ميباشد ھمم اطالعات یوحا يهمالعا اين

    در ھمم ھای خيتار به باشد.پ رایبستاکنممماش زينهھ اختدپر در مککيا تان بيمهوشش حقظ

    Premera Blue Cross طريق از ماش مهبيوشش يا و تقاضا ای پ. يدماين جهتو يهمالعا اين

    حق شما. يدشاب داشته اجتياح صیاخ کارھای امانج برای صیمشخ ایھ خيتار به تان، انیمدر ھای کسب برای .نماييد دريافت گانيرا ورط به ودخ زبان به را کمک و اطالعات اين که داريد را اين

    استم ) 5357-842-800 مارهباش ماست TTY انکاربر(800-722-1471 مارهش با اطالعات .اييدنم برقرار

    Polskie (Polish): To ogłoszenie może zawierać ważne informacje. To ogłoszenie może

    zawierać ważne informacje odnośnie Państwa wniosku lub zakresu świadczeń poprzez Premera Blue Cross. Prosimy zwrócic uwagę na kluczowe daty, które mogą być zawarte w tym ogłoszeniu aby nie przekroczyć terminów w przypadku utrzymania polisy ubezpieczeniowej lub pomocy związanej z kosztami. Macie Państwo prawo do bezpłatnej informacji we własnym języku. Zadzwońcie pod 800-722-1471 (TTY: 800-842-5357).

    Português (Portuguese): Este aviso contém informações importantes. Este aviso poderá conter informações importantes a respeito de sua aplicação ou cobertura por meio do Premera Blue Cross. Poderão existir datas importantes neste aviso. Talvez seja necessário que você tome providências dentro de determinados prazos para manter sua cobertura de saúde ou ajuda de custos. Você tem o direito de obter e sta informação e ajuda em seu idioma e sem custos. Ligue para 800-722-1471 (TTY: 800-842-5357).

    Română (Romanian): Prezenta notificare conține informații importante. Această notificare poate conține informații importante privind cererea sau acoperirea asigurării dumneavoastre de sănătate prin Premera Blue Cross. Pot exista date cheie în această notificare. Este posibil să fie nevoie să acționați până la anumite termene limită pentru a vă menține acoperirea asigurării de sănătate sau asistența privitoare la costuri. Aveți dreptul de a obține gratuit aceste informații și ajutor în limba dumneavoastră. Sunați la 800-722-1471 (TTY: 800-842-5357).

    Pусский (Russian): Настоящее уведомление содержит важную информацию. Это уведомление может содержать важную информацию о вашем заявлении или страховом покрытии через Premera Blue Cross. В настоящем уведомлении могут быть указаны ключевые даты. Вам, возможно, потребуется принять меры к определенным предельным срокам для сохранения страхового покрытия или помощи с расходами. Вы имеете право на бесплатное получение этой информации и помощь на вашем языке. Звоните по телефону 800-722-1471 (TTY: 800-842-5357).

    Fa’asamoa (Samoan): Atonu ua iai i lenei fa’asilasilaga ni fa’amatalaga e sili ona taua e tatau ona e malamalama i ai. O lenei fa’asilasilaga o se fesoasoani e fa’amatala atili i ai i le tulaga o le polokalame, Premera Blue Cross, ua e tau fia maua atu i ai. Fa’amolemole, ia e iloilo fa’alelei i aso fa’apitoa olo’o iai i lenei fa’asilasilaga taua. Masalo o le’a iai ni feau e tatau ona e faia ao le’i aulia le aso ua ta’ua i lenei fa’asilasilaga ina ia e iai pea ma maua fesoasoani mai ai i le polokalame a le Malo olo’o e iai i ai. Olo’o iai iate oe le aia tatau e maua atu i lenei fa’asilasilaga ma lenei fa’matalaga i legagana e te malamalama i ai aunoa ma se togiga tupe. Vili atu i le telefoni 800-722-1471 (TTY: 800-842-5357).

    Español ( ): Este Aviso contiene información importante. Es posible que este aviso contenga información importante acerca de su solicitud o cobertura a través de Premera Blue Cross. Es posible que haya fechas clave en este

    tiene derecho a recibir esta información y ayuda en su idioma sin costo

    aviso. Es posible que deba tomar alguna medida antes de determinadas fechas para mantener su cobertura médica o ayuda con los costos. Usted

    alguno. Llame al 800-722-1471 (TTY: 800-842-5357).

    Spanish

    Tagalog (Tagalog): Ang Paunawa na ito ay naglalaman ng mahalagang impormasyon. Ang paunawa na ito ay maaaring naglalaman ng mahalagang impormasyon tungkol sa iyong aplikasyon o pagsakop sa pamamagitan ng Premera Blue Cross. Maaaring may mga mahalagang petsa dito sa paunawa. Maaring mangailangan ka na magsagawa ng hakbang sa ilang mga itinakdang panahon upang mapanatili ang iyong pagsakop sa kalusugan o tulong na walang gastos. May karapatan ka na makakuha ng ganitong impormasyon at tulong sa iyong wika ng walang gastos. Tumawag sa 800-722-1471 (TTY: 800-842-5357).

    ไทย (Thai): ประกาศนมขอมลสาคญ ประกาศนอาจมขอมลทสาคญเกยวกบการการสมครหรอขอบเขตประกน สขภาพของคณผาน Premera Blue Cross และอาจมกาหนดการในประกาศน คณอาจจะตอง ดาเนนการภายในกาหนดระยะเวลาทแนนอนเพอจะรกษาการประกนสขภาพของคณหรอการชวยเหลอท มคาใชจาย คณมสทธทจะไดรบขอมลและความชวยเหลอนในภาษาของคณโดยไม่มคาใชจาย โทร 800-722-1471 (TTY: 800-842-5357)

    ้ี ี ้ ู ํ ั ้ี ี ้ ู ่ี ํ ั ่ี ั ั ื ัุ ุ ่ ี ํ ี ุ ้ํ ิ ํ ่ี ่ ่ื ั ั ุ ุ ื ่ ื ่ีี ่ ้ ่ ุ ี ิ ิ ่ี ้ ั ้ ู ่ ื ้ี ุ ี ่ ้ ่

    Український (Ukrainian): Це повідомлення містить важливу інформацію. Це повідомлення може містити важливу інформацію про Ваше звернення щодо страхувального покриття через Premera Blue Cross. Зверніть увагу на ключові дати, які можуть бути вказані у цьому повідомленні. Існує імовірність того, що Вам треба буде здійснити певні кроки у конкретні кінцеві строки для того, щоб зберегти Ваше медичне страхування або отримати фінансову допомогу. У Вас є право на отримання цієї інформації та допомоги безкоштовно на Вашій рідній мові. Дзвоніть за номером телефону 800-722-1471 (TTY: 800-842-5357).

    Tiếng Việt (Vietnamese): Thông báo này cung cấp thông tin quan trọng. Thông báo này có thông tin quan trọng về đơn xin tham gia hoặc hợp đồng bảo hiểm của quý vị qua chương trình Premera Blue Cross. Xin xem ngày quan trọng trong thông báo này. Quý vị có thể phải thực hiện theo thông báo đúng trong thời hạn để duy trì bảo hiểm sức khỏe hoặc được trợ giúp thêm về chi phí. Quý vị có quyền được biết thông tin này và được trợ giúp bằng ngôn ngữ của mình miễn phí. Xin gọi số 800-722-1471 (TTY: 800-842-5357).