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A New Route to Science Innovation
Why we should rethink how to compensate,
fund, and “own” scientific innovations.
How should this be done? Insights and
ideas from a host of sources.
Bradly Alicea
Scientific Innovation Fellow
Orthogonal Research
MONEY
TANGIBLE
OUTCOME
INTANGIBLE
FEATURES
Blog posts:
Gobbledygook: http://blogs.plos.org/mfenner/2012/03/27/marketing-for-scientists/
Synthetic Daisies: http://syntheticdaisies.blogspot.com/search/label/alternative-models
Set of Articles (Nature):
Nature Materials, 11 (April 2012): “One-click Science Marketing”, “The ‘M’ Word”, “The
Scientific Marketplace”.
What does a market-based economy for science look like?
* job market, competition for grants (supply-side economics).
* tangible products (protocols, code, technologies), intellectual property (must these be
privatized to be maximally beneficial?). What about intangible products?
* barriers to entry (falling? Citizen science….), strategy (imitation, cooperation, competition?)
A gentle introduction……
IP via Patent model:
Scientists, Engineers
University Administration,
Patent Attorneys Market
We own the technical
expertise, but not the
market power.
Is this innovation via rent-seeking?
Rent-seeking: extracting value (in the form of
rents) for access to patent space.
Do we need a middleman to partition markets, or
can we take smaller chunks with a higher overall
payoff?
Rent-seeking vs. value-addition: which is a better
way to characterize this relationship?
RENT-SEEKING OR
VALUE-ADDITION?
The only route to
compensating innovators?
% innovations
with payoff
Skewed towards
tangible goods
PAYOFF
PROMISE, LIMITED PAYOFF
MORE WORK
NEEDED, INTANGIBLE
Barrier to dividends:
1) significant proof-of-
concept required.
2) valuable
components become
proprietary.
3) pure science
proceeds in “fits-and-
starts”, tangential
progress.
IP via Patent Model: The Patent Problem
Steven Levy, Wired Opinion,
11/13/2012.
* patents are not only protection
for ideas, but are assets (with
intrinsic value) in and of
themselves.
* patent process is slow, difficult,
and can potentially stifle further
innovation.
Role of patents:
* True value creation (strategic
partitioning of innovation
space)?
* Largely rent-seeking
(enclosure of innovation
space)?
Barrier to dividend: amount of investment (effort, money)
needed to yield return, additional value.
ALTERNATE MODEL:
* raise money in increments (divide project into
modules).
* add value as discoveries are made (not a
linear process).
* modules and payoffs are specific to
applications, market.
Open-source ethos:
1) offer some things free (knowledge,
protocols).
2) market other things for a fee (templates,
technology design).
3) MOOC model: offer webcasts of techniques
to a wide audience (economy of scale).
Amount of work
contributed by
module #5
EXAMPLE: moving from questions to findings and technologies
Added value
contributed by
module #5
What are the options?
2) open-source models
* open to the public, versioning (drives
development forward).
* donation-driven, premium components (non-
profit foundation).
1) commercialization
* significant proof-of-concept required (must be
novel but practical).
* IP protection (proprietary), start-up potential.
What are the options?
4) X-prize style challenges
raise money (venture capital) and grand prize is
competitive.
* have fun, single winner -- end up with tangible set
of tools going forward.
3) distributed fundraising
* existing sites: Kickstarter, SciFlies, IndieGoGo.
Blog post: http://syntheticdaisies.blogspot.com
* funding window – raise x amount of dollars in n
months.
* get paid as you go. ……
IDEAS!
Social network member
i3, plus external funders
(circle at lower right)
Social network member
i6, plus external funders
(circle at lower right) How much funding is
raised within the social
network (i ϵ N) versus
from external
sources?
CROWDSOURCING: an inbred
capital market?
Change the way we do business? Or simply adapt?
Edison Dyson Pasteur
Have both a pure and applied research strategy:
* pure and applied research can potentially cross-fertilize each other.
* what is the style of famous inventors?
“I have not failed, I’ve just
found 10,000 ways that
won’t work”
“There are no such things
as applied sciences, only
applications of science”.
“Enjoy failure and learn
from it. You can never
learn from success”.
IDEA
MODEL
EXPERIMENT
UNIT OF
INVESTMENT
TEST
INVESTMENT
(crowdsourced)
APPLICATION
PROTOTYPING
FURTHER
INVESTMENT
REAL-WORLD
TESTING
VIRTUAL (THEORETICAL)
TESTING
Prototype of alternative
funding and investment
model
From conception (idea) to production and potential for
value-addition (testing)
Alternative Models of Value
How do we define “value”? Do we need an “economy of science”?
Other cultures: economic and intellectual (religious) worlds are joined at the hip.
OUTCOME: religious activities had monetary (symbolic capital) value.
Virtual Worlds (Second Life): Linden Dollars
USD (1) LindeX currency
exchange L$ (260)
Self-contained Market
Buy Land Sell Land Buy Clothing
Lesson from Shareholder Value
Shareholder value: the point of a corporation is to create value for shareholders
(investors), not to create a product per se.
* what an entity does (e.g. product development) is ancillary to the value of its assets
(usually specialized in one market niche, or as an expansionary entity).
“Down With Shareholder Value”
Joe Nocera, NYT, 8/10/2012.
Theory of shareholder value………
* if you invest in a scientific enterprise (outside of a funding
agency), what kinds of returns should you expect?
* What kind of value can be generated through
collaborations (Nash equilibrium version of a hostile
takeover)?
Prediction Markets (a.k.a. Ideas Futures)
InTrade, Iowa Prediction Markets, Hollywood Stock Exchange:
EXAMPLE: Bets of Bitcoin
Take a position (yes/no)
Pay market price
Price based on probability
of event
YES = 90% chance of event occurring,
$9.00 per security.
Use virtual currency to make trades on events.
Statement made on a real-world problem:
“Bitcoin will be exchanged for less than $13 USD at
the end of December 31st, 2012” (over finite time
window).
* weighted bet: the earlier you place winning
position, the higher your return.
Research “Strategy”
Be careful, this is NOT what is sounds like (nor a trick question)….
What questions do you ask? What kind of approaches do you pursue?
* things that are similar to the community standard, or cutting-edge, “out there”
questions?
Do you compete with other labs, or collaborate closely?
Are you an imitator (pure strategy), or an innovator (mixed strategy)?
* some of these choices are a consequence of the scientific infrastructure (previous
training, journal expectations, access to data and tools).
x, y, z x, y, z
x, y, z x, y, z
IMITATOR
INNOVATOR
COMPETE COLLABORATE
Becomes an m-strategy (4),
n-player (3) game,
Production of Pens
(cost/unit)
Production of Tablet
PCs (cost/unit)
Educational/research
Infrastructure (cost/unit)
What it enables (information/
value transformation)
What it enables (information/
value transformation)
What it enables (information/
value transformation)
MODEL OF INTANGIBLE VALUE (VALUE TRANSFORMATION)
Anthropological Models of Value (defined by cultural change)
Transformity (energy and information)
Value Transformation
How do you make your research area
“robust” (as a market)?
Investment Bubbles: two examples
Housing “bubble” = massive overvaluation of price per unit, unit is highly tangible (easy to
assess true value).
* bursting of bubble results in an unstable price trajectory (severe overshoot, undershoot in
prices).
Education “bubble” = massive increase in tuition rates, is this overvaluation (per unit)? Unit is
highly intangible (harder to assess true value).
* bursting of bubble results in a more robust price trajectory (some deflation, but slower and
easier for market to adapt).
So what is the secret recipe?
* a few big investors, or many small investors?
* is there a market for “promise”? See Facebook,
IPO offerings…..
* advertising drives Google’s profitability – is a
side business required?
* will “distributed funding sources” = a sufficient
budget?
Is “proprietary science” at odds with the
collaboration culture of modern science?
* can we adapt an “open source foundation”
model for knowledge generation, access to
data?