A. Paternal DMRs

B. Maternal DMRs

(a)

(d) (e) (f)

(c)

Blood Sperm Blood Sperm Blood Sperm

Blood Sperm Blood Sperm Blood Sperm

2q33.3 14q32

1p31 4q21-q22 6p25.2

Supplementary Figure 1

(b)

11p15.5

(g) (h) (i)

Blood Sperm Blood Sperm Blood Sperm

6q24-q25 7p12.2 7q21

(j) (k) (l)

Blood Sperm Blood Sperm Blood Sperm

7q32 10q26.11 11p15

1 2 3 4 5 6 7 8 -11 12-15 16 17

(n)

(m) (o)

(q) (r)

Blood Blood Sperm Blood Sperm

Blood Sperm Blood Sperm Blood Sperm

(n)

13q14.2 15q11.2 16p13.3

19q13.42 19q13.4 20q11.2

Sperm

v

(p) (q) (r)

C. Non-imprinted regions

(s) (t) (u)

Blood Sperm Blood Sperm Blood Sperm

Blood Sperm Blood Sperm Blood Sperm

20q11.2-q12 20q13.12 20q13.32

20q13.3

LINE-1(X58075) Alu(U14568)(v) (w) (x)