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A Study Comparing Visible Red and Infrared Wavelengths for Dental Analgesia Tottenham, Ontario Canada Gerry Ross, DDS

A Study Comparing Visible Red and Infrared …...A Study Comparing Visible Red and Infrared Wavelengths for Dental Analgesia Tottenham, Ontario Canada Gerry Ross, DDS Disclosure: Dr

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Page 1: A Study Comparing Visible Red and Infrared …...A Study Comparing Visible Red and Infrared Wavelengths for Dental Analgesia Tottenham, Ontario Canada Gerry Ross, DDS Disclosure: Dr

A Study Comparing Visible Red and Infrared Wavelengths for Dental

Analgesia

Tottenham, Ontario Canada

Gerry Ross, DDS

Page 2: A Study Comparing Visible Red and Infrared …...A Study Comparing Visible Red and Infrared Wavelengths for Dental Analgesia Tottenham, Ontario Canada Gerry Ross, DDS Disclosure: Dr

Disclosure:

Dr. Ross provides education and training for Zolar Surgical Diode lasers, for which he receives a fee. No company had any contribution to this presentation. No funding was received for this presentation.

Page 3: A Study Comparing Visible Red and Infrared …...A Study Comparing Visible Red and Infrared Wavelengths for Dental Analgesia Tottenham, Ontario Canada Gerry Ross, DDS Disclosure: Dr

Low Level Laser Therapy (LLLT), also

known as phototherapy or

photobiomodulation, uses light energy in

the form of photons from low level lasers

or superluminous diodes to elicit cellular

and biological responses in the body.

Page 4: A Study Comparing Visible Red and Infrared …...A Study Comparing Visible Red and Infrared Wavelengths for Dental Analgesia Tottenham, Ontario Canada Gerry Ross, DDS Disclosure: Dr

DENTAL ANALGESIA

Laser therapy has been demonstrated to have a significant impact on nerve cells.

• Dental pulp innervated by non-myelinated C fibres.

• As a result, Laser Therapy is used frequently for dental analgesia pre-operatively and post-operatively.

• Can be used in most primary teeth and in small restorations in adults.

Page 5: A Study Comparing Visible Red and Infrared …...A Study Comparing Visible Red and Infrared Wavelengths for Dental Analgesia Tottenham, Ontario Canada Gerry Ross, DDS Disclosure: Dr

MECHANISMS OF ACTION

• Laser irradiation stabilizes the nerve

membrane through an increase in adenosine

triphosphate (ATP) production and enhanced

redox systems of the cell

• The stabilization of the nerve membrane

increases neural latency and decreases pain

transmission.

Markovic AB, Todorovic L

Oral Surg Oral Med Oral Pathol Oral Radiol Endod

Page 6: A Study Comparing Visible Red and Infrared …...A Study Comparing Visible Red and Infrared Wavelengths for Dental Analgesia Tottenham, Ontario Canada Gerry Ross, DDS Disclosure: Dr

• Photons delivered along the path of the nerve

can inhibit or partially block nerve conduction.

Chow RT, Johnson MI, Lopes-Martins RAB, Bjordal JM

The Lancet 2010

MECHANISMS OF ACTION

Page 7: A Study Comparing Visible Red and Infrared …...A Study Comparing Visible Red and Infrared Wavelengths for Dental Analgesia Tottenham, Ontario Canada Gerry Ross, DDS Disclosure: Dr

Disruption in mitochondrial movement following 650nm LI

Before LI

After LI

*diagram not to scale Slide courtesy of Roberta Chow

Page 8: A Study Comparing Visible Red and Infrared …...A Study Comparing Visible Red and Infrared Wavelengths for Dental Analgesia Tottenham, Ontario Canada Gerry Ross, DDS Disclosure: Dr

• Dental pulp innervated

by non-myelinated C

Fibers

• Laser irradiation

reduces the

conduction of Aδ and

C fibres (small

diameter fibres), both

of which transmit

nocioceptive pain.

Chow RT, Armati P, Laasko EL, Bjordal JM, Baxter GD

Photomed and Laser Surg 2011

MECHANISMS OF ACTION

Page 9: A Study Comparing Visible Red and Infrared …...A Study Comparing Visible Red and Infrared Wavelengths for Dental Analgesia Tottenham, Ontario Canada Gerry Ross, DDS Disclosure: Dr

• Production and release of endogenous opiods

(β-endorphins)

Pozzo DH, Fregapani PW et al

Med Oral Pathol Oral Cir Bucal 2008

MECHANISMS OF ACTION

Page 10: A Study Comparing Visible Red and Infrared …...A Study Comparing Visible Red and Infrared Wavelengths for Dental Analgesia Tottenham, Ontario Canada Gerry Ross, DDS Disclosure: Dr

• Analgesia at an irradiation at

9J/cm² was shown to last for 1hr.

• Studies have shown that laser

irradiation reduces pain more

significantly when applied in

higher doses.

• This follows the principle of the

Arndt Schultz law, which states that

bioinhibition occurs with higher

energy densities.

Cidral-Filho FJ, Mazzardo-Martings L et al.

Lasers Med Sci 2013

MECHANISMS OF ACTION

Page 11: A Study Comparing Visible Red and Infrared …...A Study Comparing Visible Red and Infrared Wavelengths for Dental Analgesia Tottenham, Ontario Canada Gerry Ross, DDS Disclosure: Dr

PURPOSE OF STUDY

• To compare visible Red-660nm and Infrared-

808nm laser irradiation for dental analgesia.

Page 12: A Study Comparing Visible Red and Infrared …...A Study Comparing Visible Red and Infrared Wavelengths for Dental Analgesia Tottenham, Ontario Canada Gerry Ross, DDS Disclosure: Dr

DESIGN OF STUDY

• 100 teeth for each wavelength

• Wavelength alternated every 20 teeth

• Study explained to patients and they could elect

Laser or Local Anaesthetic

• Teeth selected were cases where analgesia was a

good option; small to moderate restorations, crown

cementation and cases where patients requested “no

freezing”

• Same dose use for each wavelength

• Patients rated pain on VAS Scale (0-10)

Page 13: A Study Comparing Visible Red and Infrared …...A Study Comparing Visible Red and Infrared Wavelengths for Dental Analgesia Tottenham, Ontario Canada Gerry Ross, DDS Disclosure: Dr

LASER

• Konf (Taiwan) Dual-Wave laser

• Laser has 2 interchangeable heads 660nm 150mw

Red and 808nm 250 mw Infrared

• Because there were 2 heads of same laser the J/cm²

were identical

Page 14: A Study Comparing Visible Red and Infrared …...A Study Comparing Visible Red and Infrared Wavelengths for Dental Analgesia Tottenham, Ontario Canada Gerry Ross, DDS Disclosure: Dr

LASER PARAMETERS

Infrared Laser Red Laser

Wavelength 808 nm 660 nm

Power 250 mW 150 mW

Contact vs Non Contact Contact Contact

Frequency CW CW

Size of Tip 8 mm 8 mm

Energy Density 390 mW/cm² 234 mW/cm²

Joules 16J (64 sec) 16J (112 sec)

Fluence 25 J/cm² 25 J/cm²

Page 15: A Study Comparing Visible Red and Infrared …...A Study Comparing Visible Red and Infrared Wavelengths for Dental Analgesia Tottenham, Ontario Canada Gerry Ross, DDS Disclosure: Dr

TECHNIQUE

• 16 Joules to apex of each root according to

Application diagrams

• Application on tooth

• If can access caries - 16J at site

• If interproximal - 16J at Buccal CEJ

• Crown cementation- apex 1st and then remove

temporary and 8J at each of Buccal, Occlusal and

Lingual

Page 16: A Study Comparing Visible Red and Infrared …...A Study Comparing Visible Red and Infrared Wavelengths for Dental Analgesia Tottenham, Ontario Canada Gerry Ross, DDS Disclosure: Dr

Application Guide for Dental Analgesia

Primary Dentition Permanent Dentition

Page 17: A Study Comparing Visible Red and Infrared …...A Study Comparing Visible Red and Infrared Wavelengths for Dental Analgesia Tottenham, Ontario Canada Gerry Ross, DDS Disclosure: Dr
Page 18: A Study Comparing Visible Red and Infrared …...A Study Comparing Visible Red and Infrared Wavelengths for Dental Analgesia Tottenham, Ontario Canada Gerry Ross, DDS Disclosure: Dr
Page 19: A Study Comparing Visible Red and Infrared …...A Study Comparing Visible Red and Infrared Wavelengths for Dental Analgesia Tottenham, Ontario Canada Gerry Ross, DDS Disclosure: Dr
Page 20: A Study Comparing Visible Red and Infrared …...A Study Comparing Visible Red and Infrared Wavelengths for Dental Analgesia Tottenham, Ontario Canada Gerry Ross, DDS Disclosure: Dr

RESULTS

0

10

20

30

40

50

60

70

80

90

0 1 2 3 4 5 6 7 8 9 10

Nu

mb

er o

f P

atie

nts

VAS Score

Comparison of Red and Infrared Laser for Dental Analgesia

Infrared Laser

Red Laser

Page 21: A Study Comparing Visible Red and Infrared …...A Study Comparing Visible Red and Infrared Wavelengths for Dental Analgesia Tottenham, Ontario Canada Gerry Ross, DDS Disclosure: Dr

CONCLUSION

• Laser irradiation at a fluence of 25 J/cm² with both

Red (660nm) and Infrared (808nm) was effective for

dental analgesia.

• None of the treated teeth required dental anesthesia

and was well received by all patients.

• Future studies investigating different fluences and

application points could lead to dental anesthesia.

Page 22: A Study Comparing Visible Red and Infrared …...A Study Comparing Visible Red and Infrared Wavelengths for Dental Analgesia Tottenham, Ontario Canada Gerry Ross, DDS Disclosure: Dr

Join us for

Photobiomodulation: Mainstream Medicine

and Beyond

Registration information and abstract submission

www.naalt.org

NAALT ANNUAL CONFERENCEWALT BIENNIAL CONGRESS

Joint SessionSeptember 9-12, 2014

Arlington, VA