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INTRODUCTION
• Cardiovascular diseases rank number one in causing death globally.
• Lipid abnormalities like high cholesterol, triglycerides, LDL (“bad cholesterol”) and HDL (“good cholesterol”) are major risk factors for cardiovascular disease.
• Soy and fibers have been proven to improve lipid abnormalities and therefore, benefit health
AIM
• To determine the efficacy and safety of soy-based oral food supplements Relìv Now® and FibRestore® in the management of lipid abnormalities.
STUDY DESIGN
• 60-day multi-center, prospective, randomized, double-blind, placebo-controlled trial on soy-based food supplements
INCLUSION
• Adult patients (>18 years old) with lipid abnormalities which may be any of the following: high cholesterol, triglycerides, LDL
RESULTS
-15
-10
-5
0
5
10
15
20
NOW Fibrestore Placebo
Decrease in average cholesterol level after 60 days was seen only in Relìv Now® & FibRestore®
-14% -14%
19%
%
Relìv Now® FibRestore® Placebo
-18
-16
-14
-12
-10
-8
-6
-4
-2
0
2
NOW Fibrestore Placebo
-18%
-8%
1.5%
%
Decrease in LDL level after 60 days was seen only in Relìv Now® & FibRestore®
Relìv Now® FibRestore® Placebo
Triglyceride level was reduced by FibRestore® after 60 days
-14
-12
-10
-8
-6
-4
-2
0
NOW Fibrestore Placebo
-1.2%
-12.4%
-10%
%
Relìv Now® FibRestore® Placebo
FibRestore® had greater reduction in fasting plasma glucose level after 60 days
-7
-6
-5
-4
-3
-2
-1
0
1
2
NOW Fibrestore Placebo
2%
-6.4%
-3%
%
Relìv Now® FibRestore® Placebo
-18
-16
-14
-12
-10
-8
-6
-4
-2
0
NOW Fibrestore Placebo
-10.4%
-16.7%
-6%
%
Relìv Now® & FibRestore® showed reduction in blood uric acid levels after 60 days
Relìv Now® FibRestore® Placebo
Changes in average weight after 60 days
-8
-7
-6
-5
-4
-3
-2
-1
0
1
NOW Fibrestore Placebo
-7.4%
0.4%
-0.9%
%
Relìv Now® FibRestore® Placebo
Relìv Now® & FibRestore® showed greater reduction in cholesterol and triglycerides among
diabetic subjects
-35
-30
-25
-20
-15
-10
-5
0
5
10
NOW Fibrestore Placebo
Cholesterol Triglyceride
-17%
-11.3%
%
-4%
8%
-33.2% -29%
Relìv Now® FibRestore® Placebo
Relìv Now® & FibRestore® showed greater reduction in cholesterol among overweight subjects
-16
-14
-12
-10
-8
-6
-4
-2
0
2
-3%
%
-14.6%
0.4%
Relìv Now® FibRestore® Placebo
SUMMARY
Relìv Now® and FibRestore®: • Reduced average cholesterol by 14% • Reduced average LDL by 18% and 8%, respectively • Reduced average triglycerides by 1.2% and 12.4%,
respectively • Reduced average uric acid by 10.4% and 16.7%,
respectively • Greater reduction in cholesterol and triglycerides
among diabetic or overweight individuals
CONCLUSION
This study proved that Relìv® Now and FibRestore® are effective food supplements in correcting lipid abnormalities and hence, may help in lowering the risk for cardiovascular disease.