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„2 in 1“ Stentgraft to reduce aortic coverage in T-Branch P.M. Kasprzak University of Regensburg Disclosures (grants, speaker fee, development, patents): Cook, Gore, Vascutek, Bard, Atrium, Aptus, Maquet, UCB

„2 in 1“ Stentgraft to reduce aortic coverage in T-Branch P.M. … · T-Branch seal in the distal descending aorta with diameter 30-38mm without extension of the aortic coverage

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Page 1: „2 in 1“ Stentgraft to reduce aortic coverage in T-Branch P.M. … · T-Branch seal in the distal descending aorta with diameter 30-38mm without extension of the aortic coverage

„2 in 1“ Stentgraft

to reduce aortic coverage

in T-Branch

P.M. Kasprzak

University of Regensburg

Disclosures (grants, speaker fee, development, patents):

Cook, Gore, Vascutek, Bard, Atrium, Aptus, Maquet, UCB

Page 2: „2 in 1“ Stentgraft to reduce aortic coverage in T-Branch P.M. … · T-Branch seal in the distal descending aorta with diameter 30-38mm without extension of the aortic coverage

Neurologic Complications after TEVAR

• Spinal cord ischemia (SCI) 0 - 12,5%(1)

• Stroke 0 - 9,5%(2)

Literaturquelle n Device Aortenpathologie 30-Tages Ğ

MortalitŠt (%)

SCI

(%)

Stroke

(%)

Mitchell et al

1999

103 Home-made DA/Diss/PAU 9 2 6,8

Greenberg et al

2000

100 Zenith DA/Diss 7 1 3

Cambria et al

2002

105 k.A. k.A. 7,6 4,8 9,5

Bortone et al

2004

110 TAG/Talent DA/Diss/PseudoA 3,6 0 1

Wheatly et al

2006

156 TAG DA/Diss/PseudoA/PAU 3,8 0,6 4,5

Fattori et al

2006

457 Talent/Zenith DA/Diss/Trauma 5 1,7 3,7

Lee et al

2007

121 TAG/Zenith/Talent DA/Diss/PAU 5 6,6 4,1

Bavaria et al

2007

140 TAG DA 2,1 2,9 3,6

Zipfel et al

2008

337 E-vita/Relay DA/Diss/Trauma 12,7 1,5 2,6

Morales et al

2008

160 Zentith DA/Diss 6,9 3,1 3,1

Fairman et al

2008

195 Talent DA 2,1 8,7 3,6

Maximalwerte:(1)Schlösser et al 2009(2)Stone et al 2006, Cambria et al 2002

Page 3: „2 in 1“ Stentgraft to reduce aortic coverage in T-Branch P.M. … · T-Branch seal in the distal descending aorta with diameter 30-38mm without extension of the aortic coverage

D.E., 68 years - temporary paraplegia postoperativ

Page 4: „2 in 1“ Stentgraft to reduce aortic coverage in T-Branch P.M. … · T-Branch seal in the distal descending aorta with diameter 30-38mm without extension of the aortic coverage

Universitätsklinikum Regensburg

• Risk of paraplegia during BEVAR

varies between 10 – 25 %

Thorakoabdominal aortic aneurysms (TAAA)

O´Callaghan A et al., J Vasc Surg 2015; 61:347-354.

Dias NV et al. Eur J Vasc Endovac Surg 2015; 49: 403-409.

Kasprzak PM et al. Eur J Vsc Endovasc Surg 2014: 48: 258-265.

Verhoeven ELG et al. Eur J Vasc Endovasc Surg 2015; 49: 524-531.

Bisdas T et al. J Vasc Surg 2015; 61: 1408-1416.

Page 5: „2 in 1“ Stentgraft to reduce aortic coverage in T-Branch P.M. … · T-Branch seal in the distal descending aorta with diameter 30-38mm without extension of the aortic coverage
Page 6: „2 in 1“ Stentgraft to reduce aortic coverage in T-Branch P.M. … · T-Branch seal in the distal descending aorta with diameter 30-38mm without extension of the aortic coverage

Risk factors for paraplegia:

- Overstenting LSA

- Infrarenal surgical graft (Tube, Y) or Stentgraft

- Length of aortic coverage

- Immediate thrombosis of aneurysm

- Hypotension peri- / postoperativ

- No Spinaldrainage ?

Page 7: „2 in 1“ Stentgraft to reduce aortic coverage in T-Branch P.M. … · T-Branch seal in the distal descending aorta with diameter 30-38mm without extension of the aortic coverage

T-Branch (Cook®)

proximal diameter 34mm

distal diameter 18mm

Page 8: „2 in 1“ Stentgraft to reduce aortic coverage in T-Branch P.M. … · T-Branch seal in the distal descending aorta with diameter 30-38mm without extension of the aortic coverage

„Thoracic Reducing Union“

Page 9: „2 in 1“ Stentgraft to reduce aortic coverage in T-Branch P.M. … · T-Branch seal in the distal descending aorta with diameter 30-38mm without extension of the aortic coverage

CMD Cook®

Page 10: „2 in 1“ Stentgraft to reduce aortic coverage in T-Branch P.M. … · T-Branch seal in the distal descending aorta with diameter 30-38mm without extension of the aortic coverage

External stent graft - 38-44 mm

Internal - 32 mm

Page 11: „2 in 1“ Stentgraft to reduce aortic coverage in T-Branch P.M. … · T-Branch seal in the distal descending aorta with diameter 30-38mm without extension of the aortic coverage
Page 12: „2 in 1“ Stentgraft to reduce aortic coverage in T-Branch P.M. … · T-Branch seal in the distal descending aorta with diameter 30-38mm without extension of the aortic coverage
Page 13: „2 in 1“ Stentgraft to reduce aortic coverage in T-Branch P.M. … · T-Branch seal in the distal descending aorta with diameter 30-38mm without extension of the aortic coverage
Page 14: „2 in 1“ Stentgraft to reduce aortic coverage in T-Branch P.M. … · T-Branch seal in the distal descending aorta with diameter 30-38mm without extension of the aortic coverage
Page 15: „2 in 1“ Stentgraft to reduce aortic coverage in T-Branch P.M. … · T-Branch seal in the distal descending aorta with diameter 30-38mm without extension of the aortic coverage
Page 16: „2 in 1“ Stentgraft to reduce aortic coverage in T-Branch P.M. … · T-Branch seal in the distal descending aorta with diameter 30-38mm without extension of the aortic coverage

2015 - 16 implantations in 4 Vascular Centers

Page 17: „2 in 1“ Stentgraft to reduce aortic coverage in T-Branch P.M. … · T-Branch seal in the distal descending aorta with diameter 30-38mm without extension of the aortic coverage
Page 18: „2 in 1“ Stentgraft to reduce aortic coverage in T-Branch P.M. … · T-Branch seal in the distal descending aorta with diameter 30-38mm without extension of the aortic coverage
Page 19: „2 in 1“ Stentgraft to reduce aortic coverage in T-Branch P.M. … · T-Branch seal in the distal descending aorta with diameter 30-38mm without extension of the aortic coverage
Page 20: „2 in 1“ Stentgraft to reduce aortic coverage in T-Branch P.M. … · T-Branch seal in the distal descending aorta with diameter 30-38mm without extension of the aortic coverage

preoperative CTA scan

M, 60, symptomatic TAAA

Page 21: „2 in 1“ Stentgraft to reduce aortic coverage in T-Branch P.M. … · T-Branch seal in the distal descending aorta with diameter 30-38mm without extension of the aortic coverage
Page 22: „2 in 1“ Stentgraft to reduce aortic coverage in T-Branch P.M. … · T-Branch seal in the distal descending aorta with diameter 30-38mm without extension of the aortic coverage
Page 23: „2 in 1“ Stentgraft to reduce aortic coverage in T-Branch P.M. … · T-Branch seal in the distal descending aorta with diameter 30-38mm without extension of the aortic coverage

Regular setup in BEVAR for TAAA

- Transposition of LSA if covered

- Spinal drainage for 3-4 days (until postop. CTA) - Orbita-US

(LiquoGard7)

- open perfusion branch (TASP) and staged procedure - MEP´s

- perfusion of internal ilac arteries - Iliac-Branch

- limited coverage of the aorta

- preserving intercostal arteries

- preoperativ ASA 100mg/daily – intraoperativ Heparin with ACT>300“

Page 24: „2 in 1“ Stentgraft to reduce aortic coverage in T-Branch P.M. … · T-Branch seal in the distal descending aorta with diameter 30-38mm without extension of the aortic coverage

Conclusion

„2 in 1“ Stentgraft allows

T-Branch seal in the distal descending aorta

with diameter 30-38mm

without extension of the aortic coverage

Page 25: „2 in 1“ Stentgraft to reduce aortic coverage in T-Branch P.M. … · T-Branch seal in the distal descending aorta with diameter 30-38mm without extension of the aortic coverage

„2 in 1“ Stentgraft

to reduce aortic coverage

in T-Branch

P.M. Kasprzak

University of Regensburg

Disclosures (grants, speaker fee, development, patents):

Cook, Gore, Vascutek, Bard, Atrium, Aptus, Maquet, UCB