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www.ebmt.org #EBMT18 3 ALWP Staff Chairperson : Arnon NAGLER Secretary : Sebastian GIEBEL Subcommittees Reduced Intensity Conditioning : Bipin SAVANI Alternative Donors : Fabio CICERI Acute Lymphoid Leukemia : Sebastian GIEBEL Molecular Markers : Jordi ESTEVE Immunotherapy : Christoph SCHMID AutoHSCT : Norbert-Claude GORIN Cord Blood : Frédéric Baron Statisticians : Myriam LABOPIN Eric BEOHOU Christophe PECZYNSKI Study Coordinators : Emmanuelle POLGE Audrey MAILHOL Eva PENISSON Mohamed HOUHOU Irma KHVEDELIDZE Acute Leukemia Registry Number of HSCT (Including secondary AML and MDS transformed to AML) ADULTS (n=122978) Age med [min;max] 44 [18; 80] Male / Female 68177/ 54540 BM / PB / BM+PB CB/Double CB/ Other 31966/ 85398 / 1788 1511/ 1150/557 Id-Sibling / Other Relative / Unrelated 44690 / 8795(5528 Haplo) / 44638 Non Myeloablative 30254 AUTO ALLO 1st HSCT 22165 89007 2nd HSCT 1135 9230 3rd HSCT 228 789 Adults allografted from 2000 to 2017 Identical Sibling / OS at 5 years Adults Allografted from 2000 to 2017 Matched Unrelated / OS at 5 years Adults autografted from 2000 to 2017 OS at 5 years Adults transplanted from 2000 to 2017 37,24% 36,10% 2,44% 6,17% 1,51% 1,10% 15,45% Identical sibling Unrelated Other relative w/o HaploSCT HaploSCT CB Double CB Autografts AML 39,38% 36,81% 2,96% 5,73% 2,08% 1,27% 11,76% Identical sibling Unrelated Other relative w/o HaploSCT HaploSCT CB Double CB Autografts ALL 57 % +/- 1 CR1 (n=14762) 47 % +/- 1 CR2 (n=2840) 23 % +/- 1 Adv (n=4429) 54 % +/- 1 CR1 (n=5221) 32 % +/- 2 CR2 (n=1467) 18 % +/- 1 Adv (n=1023) 48 % +/- 1 CR1 (n=15266) 43 % +/- 1 CR2 (n=5922) 24 % +/- 1 Adv (n=7725) 52 % +/- 1 CR1 (n=5764) 33 % +/- 1 CR2 (n=2378) 15 % +/- 1 Adv (n=1310) 51 % +/- 1 CR1 (n=7241) 47 % +/- 2 CR2 (n=1070) 53 % +/- 2 CR1 (n=1522) 28 % +/- 4 CR2 (n=287) Acute Leukaemia Working Party Chair: Arnon Nagler Secretary: Sebastian Giebel

Acute Leukaemia Working Party - EBMT · 1st HSCT 22165 89007 2nd HSCT 1135 9230 3rd HSCT 228 789 Adults allografted from 2000 to 2017 Identical Sibling / OS at 5 years Adults Allografted

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Page 1: Acute Leukaemia Working Party - EBMT · 1st HSCT 22165 89007 2nd HSCT 1135 9230 3rd HSCT 228 789 Adults allografted from 2000 to 2017 Identical Sibling / OS at 5 years Adults Allografted

www.ebmt.org #EBMT18 3

ALWP Staff

Chairperson : Arnon NAGLER

Secretary : Sebastian GIEBEL

Subcommittees

Reduced Intensity Conditioning : Bipin SAVANI

Alternative Donors : Fabio CICERI

Acute Lymphoid Leukemia : Sebastian GIEBEL

Molecular Markers : Jordi ESTEVE

Immunotherapy : Christoph SCHMID

AutoHSCT : Norbert-Claude GORIN

Cord Blood : Frédéric Baron

Statisticians : Myriam LABOPIN

Eric BEOHOU

Christophe PECZYNSKI

Study Coordinators : Emmanuelle POLGE

Audrey MAILHOL

Eva PENISSON

Mohamed HOUHOU

Irma KHVEDELIDZE

Acute Leukemia Registry

Number of HSCT

(Including secondary AML and MDS transformed to AML)

ADULTS

(n=122978)

Age med [min;max] 44 [18; 80]

Male / Female 68177/ 54540

BM / PB / BM+PB

CB/Double CB/ Other

31966/ 85398 / 1788

1511/ 1150/557

Id-Sibling / Other Relative / Unrelated

44690 / 8795(5528 Haplo) / 44638

Non Myeloablative 30254

AUTO ALLO

1st HSCT 22165 89007

2nd HSCT 1135 9230

3rd HSCT 228 789

Adults allografted from 2000 to 2017 Identical

Sibling / OS at 5 years

Adults Allografted from 2000 to 2017

Matched Unrelated / OS at 5 years

Adults autografted from 2000 to 2017

OS at 5 years

Adults transplanted from 2000 to 2017

37,24%

36,10%

2,44%

6,17%

1,51%

1,10%

15,45%

Identical sibling

Unrelated

Other relative w/o HaploSCT

HaploSCT

CB

Double CB

Autografts

AML

39,38%

36,81%

2,96% 5,73%

2,08%

1,27%

11,76%

Identical sibling

Unrelated

Other relative w/o HaploSCT

HaploSCT

CB

Double CB

Autografts

ALL

57 % +/- 1 CR1 (n=14762)

47 % +/- 1

CR2 (n=2840)

23 % +/- 1 Adv (n=4429)

54 % +/- 1 CR1 (n=5221)

32 % +/- 2 CR2 (n=1467)

18 % +/- 1 Adv (n=1023)

48 % +/- 1 CR1 (n=15266)

43 % +/- 1 CR2 (n=5922)

24 % +/- 1 Adv (n=7725)

52 % +/- 1 CR1 (n=5764)

33 % +/- 1 CR2 (n=2378)

15 % +/- 1 Adv (n=1310)

51 % +/- 1 CR1 (n=7241)

47 % +/- 2 CR2 (n=1070)

53 % +/- 2 CR1 (n=1522)

28 % +/- 4 CR2 (n=287)

Acute Leukaemia

Working Party

Chair: Arnon Nagler

Secretary: Sebastian Giebel