Agricultural Biotechnology

in Mongolia

Dr.Altankhuyag – Institute of Animal Husbandry Dr.Batsukh - Institute of Veterinary Medicine

What we understand Biotechnology

Biotechnology is a science includes various aspects of the management and manipulation of biological systems

Biotechnology is an integrated use of:

• Biochemistry

• Microbiology

• Chemical engineering and others

INSTITUTE OF VETERINARY MEDICINE

• 1961 - Institute of agriculture

• 1965 – Institute of animal husbandry:• veterinary medicine• animal husbandry

• 1987 - Institute of veterinary medicine with 4 regional veterinary research laboratories

•1994 – Veterinary training and research institute

•1997 – Institute of veterinary medicine

• 4 regional laboratories

Institute of Animal Husbandry

• 1944 – Agricultural sector of MAS

• 1961 – Institute of Agriculture MAS

• 1963 – Institute of Animal Husbandry

• 1987 – Research Institute of Animal Husbandry

• Branch in Gobi region

• Branch in High mountain region

School of Veterinary Medicine and Biotechnology

• 1944 – Faculty of Veterinary Medicine ,

Mongolian State University

• 1953 – Faculty of Veterinary Medicine ,

Mon.State.Univ. Agriculture

• 2001 – School of Vet Med and Biotechnology,

MSUA

Biocombinat

• Established in 1923

• Renewed by technical support of Republic of Hungary 1966-1973

• Production of bacterial, viral and mycoplasma vaccine• Production of diagnostic kits• Production of serum products

Vaccine development

About ……

• inactivated

• live

• mutant vaccines

Against;

• Bacterial

• Viral

• Mycoplasma infection

Most of technologies for the production of above vaccines are developed by Mongolian researchers…

Diagnostic kits…

About …….. different diagnostic kits including …• Brucellosis, • Salmonellosis, • Leucosis, • Q-fever,• Sarcocystosis• Gastrophilosis • Hypodermatosis • Toxoplasmosis ……. used for below diagnostic tests

CFTAGIDIHATIFATELISAs

Veterinary drugs…

Animal and plant raw materials are the main resource for the production of veterinary products . Preparation such as “Acritract” complies with not only veterinary also medical requirements.

Wide spectrum antiparasitics based on avermectin albendazole and cypermethrine homologues being developed and used in veterinary practice.

Animal tissue derived drugs (Neohystol I, II,III, Neovarilizat and etc.) are efficiently used in field of animal reproduction

Hormones and enzymes

• PMSG /pregnant mares serum gonadotrophin/

• CG /chorionic gonadotrophin/

• inhibin

• prolactin

- purified from different animal tissues:

•Pepsin

- horse and pig stomach

Mongolian dairy products are divided into:

Fatty food Proteinaceous food Fermented food

Nowadays Mongolian’s more than 40 kinds of traditional dairy products, produced by 3 basic procedures such as

Boiling with foam Curdling Souring (fermentation)

E.coli 0111E.coli 041E.coli 026E.coli 078Sal. Typi Murium 045

Sal. Typi Murium 077Staph.aureus 055MicrococcLuteus 017

By prof. Sh.Demberel

Lactobacillus Plantarum LBO 7

Effect of diarrheas in young animals:lambs - 90.0%Calves- 88.0%Therapeutic effect is 88.0 to 90.0%

Application of STH probiotics during diarrheas in children: 97.1%

EMA-1

Bam HI

Bam HI

SmaIGST

pGEX - 4T - 2

BC/48

Eco RIEco RI

Eco RIGST

pGEX - 4T - 3

Ptac

K K

Development of recombinant diagnostic kit

E.coli and Baculovirus expression systems are used for development of recombinant pGEX/EMA-1, pGEX/BC48 antigens

MaB production

• Sarcocystis tenella bradyzoite surface antigen

• Brucella abortus Outer Membrane Protein

• Horse, sheep, goat, cattle, camel and yak IgG

• development of conjugates for ELISA, IFAT

BalB/C mouse breeding

• Introduced from CLEA JAPAN INK

• Filtrated air system environment and

CE – 2 food

• Inbred breeding

• Use in Mab production

Embryo transfer of Mongolian cashmere goat

Embryo transfer adult cashmere goat

(elite flock)

Embryo transfer of sheep

8 months old embryotransfer lambs

2 weeks old lambs

3 months old lambs

New born lambs

Laparoscopic AI of sheep

New born lambs

1 year old ram

Embryo transfer cattle

AI of cattle

Thank you for your attention