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Airway Management in the ICU
Jennifer Salotto, MD Trauma, Acute Care Surgery and Critical
Care Fellow University of Colorado, Denver
July 2014
Airway Management in the ICU
• Overview: why do we care?
• Assessing the Airway
• Intubation, Adjuncts and the difficult airway
• The blocked endotracheal tube
• Unplanned extubation
• Extubation of the difficult airway
Airway: Why do we care?
• It’s the A of ABC
– No airway= no life
– brain injury in 4 min, irreversible in 7 minutes
– Cardiac arrest in minutes
• Hospitalized patients outside of the OR frequently require emergency airway management
• ETI in the ICU: high rate of immediate, severe life-threatening complications
Why are ICU airway issues unique?
• Limited physiologic reserve
• Preexisting hemodynamic instability, massive resuscitation
• No time to perform evaluation
• s/p maxillofacial, neck surgery, C-sp injury
– Upper airway edema
– expanding hematoma
Assessing the Airway
• Remember your ABC’s!
• Can the patient speak? – Assess for stridor, hoarseness, breathlessness
• Look, listen, and feel
• Place monitor, HR and O2 sats
• Assess the neck: hematoma, swelling, scars – Remove cervical collar with in-line stabilization
• Pulses, hemorrhage, IVs
Assessing the Airway
• History:
– C-spine immobilization, trauma
– Laryngectomy
– Airway problems
– Surgery?
• Invasive vs. noninvasive support
• Assess for difficult mask ventilation
Assessing the Airway
Indications for Definitive Airway Management
• Respiratory Insufficiency
• Airway Obstruction
• GCS <8
• Severe maxillofacial injury
• Inhalation injury
• Life-threatening agitation
• Expanding neck hematoma
Contraindications to Intubation
• Partial transection of the trachea
• Inability to open mouth
Rapid Sequence Intubation (RSI)
• Goal: to prevent aspiration
– use with suspected full stomach
• The National Emergency Airway Registry
– 7,712 intubations
– RSI success rate >98.5%
RSI: The Six P’s
• Preparation
• Preoxygenation
• Premedication
• Paralysis
• Passage of the ETT
• Postintubation Care
Preparation
• Monitor
• Working IV, suction, oxygen
• Oral and Nasal airways
• Bag Valve Mask
• Blades
• ETT, syringe, CO2 detector
• A SECOND PAIR OF HANDS
Positioning
• Pillows
• Sniff Position: chin lift and jaw thrust
Preoxygenation
• Bag Valve Mask: positive pressure ventilation
• Patients with respiratory failure may not have adequate response
– Baillard et al. demonstrated improved oxygenation with noninvasive positive pressure
Premedication
• Stimulation of the airway (ETT, Laryngoscope) elicits a noxious response, leading to sympathetic discharge-> HTN, tachycardia
• Agents which blunt hypertensive response:
– Opioids
– Lidocaine
• Anti-arrhythmic
– Esmolol
Induction Agents: Sedatives
• Etomidate – Single dose may cause adrenal insufficiency for up to 72 hr – Discouraged in sepsis, seizure DO – No cardiac depression
• Propofol – Rapid onset – May cause hypotension, bradycardia – Not safe in cardiac dysfunction
• Ketamine – Analgesic, sedative, amnestic – Raises HR and BP, caution in elevated ICPs, MI – Does not ablate spontaneous ventilation
• Fentanyl and Versed
– Good choice in cardiac patients
• Always have a vasopressor quickly at hand in case of hypotension
Induction Agents: Sedatives
Paralytics
• Succinylcholine – Drug of choice
– Depolarizing neuromuscular blocker
– T1/2: 5 min
– Contraindications: renal failure, hyperkalemia, burns, history of MH, crush injury, chronic debilitation
• Rocuronium – Only acceptable alternative to succs
– Cochrane review: less favored for longer half life (40 minutes) and less often “excellent” conditions
Passing the ETT
• Cricoid pressure (Sellick’s maneuver)
– introduced in 1961
– “to control regurgitation until intubation with a cuffed endotracheal tube was completed”
– occlusion of upper esophagus by back pressure on the cricoid ring against cervical vertebrae
– Hold until balloon inflated
Passing the ETT
Visualize Vocal Cords
Pass the ETT, Inflate the Balloon, Secure the Airway
Postintubation Care: Confirming Placement
• Auscultate
• ETCO2
• CXR
• bronchoscopy
Intubating with a C-Spine Injury
• Manual in-line immobilization = gold standard
– Ok to remove anterior portion of collar
• All airway maneuvers will cause some degree of neck movement
• Fiberoptic bronchoscope-assisted intubation for limited mobility
• HALO: be prepared for surgical
airway
Intubating with a C-Spine Injury
Complications of Intubation
• Cardiac arrest
• Arrhythmia
• Esophageal Intubation
• Mainstem Intubation
• Aspiration
• Pharyngeal stimulation – Bradycardia, laryngospasm
• Damage to teeth, eyes, lips, vocal cords
• Pneumothorax
Complications of ICU Intubations
– 8% difficult intubations
– 8% esophageal intubations
– 4% aspiration
– 3% mortality within 30 minutes
The Difficult Airway • “A clinical situation in which conventionally
trained anesthesiologists experience difficulty with mask ventilation, tracheal intubation, or both”
• Call for help
• Have a backup plan readily available
• Anesthesiology, Feb 2013
• Inform the patient of risks when possible
• Have an assistant
• Preoxygentate, at least 3 minutes
• Assess for
– Awake vs. GA
– Consider fiberoptics as initial approach
– Need for invasive airway
Difficult Airway Algorithm
Can’t Intubate, Nonemergent Pathway: Adjuncts to Intubation
• LMA
• Bougie
• Flexible Fiberoptics
• Rigid Fiberoptics
Laryngeal Mask Airway
• Extraglottic airway device
• No protection from aspiration
• Place along posterior pharynx into the laryngeal inlet
• May be used as a bridge to tracheostomy
• Do not use: pregnancy >16 wks, MXF trauma
Intubating Stylet (Bougie)
• Gum elastic
• For directional control when the laryngeal inlet cannot be seen
• Blind passage, confirm with clicks on the trachea
• Cheap, easy to use
Can’t Intubate, Can’t Ventilate…
• Emergent invasive airway access
Cricothyroidotomy: Surgical Airway
• An emergent procedure to secure a surgical airway
• Equipment: – Eye protection, mask
– Knife (11 or 10 blade)
– Hemostat
– ETT
– suction
Hardest Parts about a Cric:
1. Knowing when to do it
2. Knowing your anatomy
Cricothyroidotomy
• Stand on R of Pt
• Left hand stabilizes
• Initial vertical incision: avoid anterior jugular veins
• There will be blood!
Cricothyroidotomy
• Dissect down to cricothyroid membrane
• Turn knife 90 degrees, make horizontal incision and spread
• Air return will confirm
• Place ETT down, inflate
• Confirm w ETCO2 and secure
Percutaneous Cricothyroidotomy Kits
• Helm et al. 2013 – Cadaveric study
– 30 first year anesthesia residents • Open (n=15), perc (n=15)
• Open: 100% success vs. 67%
• Equal time, greater complications with perc technique
– Conclusion: the inexperienced operator, the standard open technique is safe
Other Airway Issues
• The Expanding Neck Hematoma
• Obstructed ETT
• Unplanned Extubation
• Extubation of the Difficult Airway
Expanding Neck Hematoma
The Obstructed ETT
• Secretions, kinking, biting, blood clots, cuff herniation
• Presents:
– high peak inspiratory pressures
– steadily increasing ETCO2 +/- desats
– Inspiratory volumes don’t = expiratory
Obstructed Endotracheal Tube
• 100% oxygen
• Chin lift/jaw thrust
• Attempt to pass suction catheter, bag ventilate
• If stable: irrigate, pass bronch, c/s airway exchange catheter
• If unstable: remove ETT and reintubate +/- airway exchange catheter
Airway Exchange Catheter
Unplanned Extubation
• Self-Extubation & Accidental Extubation
– 60% require reintubation
– Listello et al: 87% require reintubation within 4 hours
• Associated with longer ICU stay, vent days, morbidity and mortality
• UE incidence considered an indicator of medical and nursing care quality
• UE incidence varies widely:
– 0.5- 14.2% of patients
• 68- 95% are self-extubations
• Major risk factors: agitation, inadequate sedation, decreased patient surveillance
• Restraints controversial
– Can still reach tube, may worsen agitation
Extubation of the Difficult Airway
• Airway complications more likely with extubation
• Obesity, OSA, head/neck/airway surgery= high risk extubation failure
• Routine Extubation Criteria
• Cuff Leak test
• +/- Airway Exchange Catheter
• Steroids- Cochrane Review 2009: – In adults, multiple doses of corticosteroids begun 12-
24 hours prior to extubation do appear beneficial for patients with high risk
Extubation of the Difficult Airway
• Airway obstruction is a primary cause of respiratory distress after extubation
– Incidence 3-30%
– ~7% reintubation
In Conclusion…
• Remember your ABCs
• Call for help early
• Have a back-up plan
• Be mentally prepared for a surgical airway
• Consider all ICU airways high risk until proven otherwise
References • American Society of Anesthesiologists: Practice guidelines for the management of the difficult airway:
an updated report. Anesthesiology 2003; 98: 1269-1277. • Crosby ET. Airway management in adults after cervical spine trauma. Anesthesiology 2006; 104:1293–
1318 • Dosemeci L et al. The routine use of pediatric airway exchange catheter after extubation of adult
patients who have undergone maxillofacial or major neck surgery: a clinical observational study. Crit Care 2004; 8:R385–R390
• Helm et al. Emergency cricothyroidotomy performed by inexperienced clinicians. Emergency Medicine Journal Aug 2013; 30(8): 646-9.
• Jaber S et al. Clinical practice and risk factors for immediate complications of endotracheal intubation in the intensive care unit: a prospective, multiple center study. Crit Care Med 2006; 34:2355–2361
• Jaber S et al. Post-extubation stridor in intensive care unit patients: risk factors evaluation and importance of the cuff-leak test. Intensive Care Med 2003; 29:69–74
• Khemani et al. Corticosteroids for the prevention and treatment of post-extubation stridor in neonates, children and adults. Cochrane Database of Systematic Reviews. 2009.
• Mort TC. Preoxygenation in critically ill patients requiring emergency tracheal intubation. Crit Care Med 2005; 33: 672–2675
• Perry J et al. Rocuronium versus succinylcholine for rapid sequence induction intubation. Cochrane Database Syst Rev (database online). Issue 1, 2003.
• Reynolds SF, Heffner J. Airway management of the critically ill patient: rapid-sequence intubation. Chest 2005; 127: 1397–1412
• Schwartz et al. Death and Other Complications of Emergency Airway Management in Critically Ill Adults. Anesthesiology. 82: 367-376, 1995.
• Walz et al. Airway management in critical illness. CHEST 2007; 131:608-620.