ALIGN TECHNOLOGY, INC 1© 2019 ALIGN TECHNOLOGY, INC 1

Align Technology, Inc.John Morici, CFO

Simon Beard, SVP and Managing Directors, Americas

November 6, 2019

ALIGN TECHNOLOGY, INC 2

1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019

22 years of clear aligner leadership

Align Tech

InvisalignFDA

US OrthoConsumer Ad

IPO

EuropeUS GPs

NYU Dental School

Express 10

APAC Dist

Vivera

Invisalign Teen

EMEA Dist

Invisalign G3

Cadent iTero

Invisalign G4

Invisalign G5

SmartTrackMaterial

APAC Direct

Express 5

ClinCheck Pro

EMEA Direct

China

iTero Element

India

Japan

Invisalign G7

Invisalign G6

iTero Timelapse

$1.5B

$500M

$100M

5M Patients

4M Patients

3M Patients

2M Patients

1M Patients

100 Patients

Invisalign with Mandibular Advancement Feature

$2.0B

6M Patients

Invisalign FirstInvisalign Go

iTero Element 2 & iTero Element Flex

7M Patients

iTero Element Foundation

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Align Technology, Inc.

Invisalign system - the most advanced clear aligner system in the world

iTero intraoral scanner and services for orthodontic and restorative dentistry

As of Q3’19

$2.3BNet

revenues (LTM)

7.5MInvisalign

patients

168KTrained Invisalign

doctors

13,976Employees

worldwide

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Global strategic priorities

````

InternationalExpansion

OrthodontistUtilization

GP DentistTreat & Refer

Patient Demand& Conversion01 02 03 04

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Integrated global operations and capabilities

ZIYANG, CHINAJUAREZ, MEXICO

SAN JOSE, COSTA RICA

MADRID, SPAIN

COLOGNE, GERMANY

CHENGDU, CHINASAN JOSE, CAGlobal Headquarters

RALEIGH, NCAMERICAS Region HQ

SAU PAOLO, BRAZILLATAM Region HQ

SINGAPOREAPAC Region HQ

AMSTERDAM, The NetherlandsEMEA Region HQ WROCLAW, POLAND

MOSCOW, RUSSIAInvisalign R&D Team

OR YEHUDA, ISRAELiTero R&D & Manufacturing Ops

Order Acquisition & Manufacturing Operations

Order Acquisition

Treatment Planning

Align Offices

SHANGHAI, CHINA

YOKOHAMA, JAPAN

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Globally

orthodontic case starts per year

12M

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8.4M CasesSERVED AVAILABLE MARKET

3.6M CasesNON-APPLICABLE

70% 70%Invisalign Applicability

12M Ortho CasesTOTAL AVAILABLE MARKET

Global TAM for clear aligners is expanding

17%

12M Ortho TAM

teenagers (9M) 75%

adults (3M) 25%

Currently 17% share of SAM

8.4M SAM Align Share

teenagers (6.5M) 75% 7.6%

adults (2.1M) 25% 46.1%

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Access

potential patients by going full digital

300M

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