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Alternative Medicine
November 29th 2002
Gil C. Grimes, MD
General Data
The Diagnosis, treatment and/or prevention which complements mainstream medicine by contributing to a common whole, satisfying a demand not met by orthodoxy, or diversifying the conceptual frameworks of medicine
Ernst E et al. Complementary medicine- a definition. BJ Gen Prac 1995, 45:506
General Data
Landmark Report 1998 random sample adults USA42% used CAM in last year17% herbal therapy16% chiropractic14% massage
General Data
Austin 1998Random sample 1500 adults (80% white,
51% female 30% high school ed or less)Have you used CAM in last year
40% Yes16% chiropractic8% lifestyle diet7% exercise7% relaxation
General Data
Who is using?People with chronic health problemsMore common caucasianMore common womenMore educated
General Data
$13.7 billion unconventional therapy
$10.3 billion (75%) out of pocket
$12.8 billion out of pocket for all hospitalizations in the United States
1990 data
Eisenberg DM et al, N Engl J Med 1993 Jan 28;328(4):246-52
General Data
Increase 45.2% between 1990 and 1997
estimated at $21.2 billion 1997
$12.2 billion paid out of pocket
Eisenberg DM et al, JAMA 1998; 280:1569-1575
Getting the Truth
InforetrieverCochrane reviewNational Center for Complementary and Alternative MedicineAlternative Medicine Homepage University of PittsburghBritish Homeopathic LibraryNatural Medicine Database
Type of CAM
Herbal Medicine
Acupuncture
Nutrition
Exercise
Homeopathy
Manipulation
Massage
Meditation
Herbal Medicine
Various Forms Crude plant preparations Dried specimen Aqueous extract Tinctures Active ingredients
Herbal Medicine
Choosing the product Degree of purity Variation in potency
Look for the following Lot number Expiration date Analysis of ingredients
Acupuncture
2000 year tradition
Osler was aware of acupuncture
Alters conduction of electromagnetic signals
Alters neurotransmitters in brain
TCM relates this to a release of the Qi that is blocked
Acupuncture
EfficacyAdult postoperative N/V (1b) JAMA 1998;280:1518-24 Chemotherapy N/V (1b) JAMA 2000;284:2755-61Chronic neck pain (1b)BMJ 2001;322:1574Headache (cochrane)Menstrual cramps (cochrane)Tennis elbow, myofascial pain, carpal tunnel syndrome
National Center for Complimentary and Alternative Medicine
Acupuncture
Trouble with blinding
Sham Needles
Blinding Evaluators
Exercise
Benefits Improved respiratoryLower BPMore efficient CO Increases insulin sensitivity Improves utilization of FFA from adipose
Exercise
Physician advice Meta-analysis DARE abstract 971480
demonstrate efficacy of counseling
Exercise Rx Type of activity (aerobic etc) Intensity (60-90% Max Heart rate)
(220-Age) x 0.60 or 0.90 gives low and high end of target heart rate
Work longer low end and short bursts in high end
Exercise
Exercise RxDuration
Inversely proportional to the intensityRate fatigue one hour after exercise to judge
Frequency3-5 sessions per weekNo greater than 48 hours off
Exercise
Three phases of exerciseWarm upConditioningCool downStretch some before and always after
Homeopathy
Treats illness with progressively dilute substances that produce similar pattern of injury
Treating like with like
Therapy is individualized to the patient
Meta-analysis of homeopathy trials Lancet 1997;350:834-43
Cystitis
CranberryRandomised trial of cranberry-ligonberry
juice and Lactobacillus GG drink for the prevention of UTI in women. BMJ2001;322:1-5 (LOE 1c)
Glass of unsweetened cranberry juice a day
NNT=5 at 12 months to reduce frequnecy of UTI from 36% to 16%
Migraine
Riboflavin 400 mg Riboflavin daily (LOA 1b) NNT= 2.8 to reduce frequency of attacks per
month (56% to 19%) NNT= 2.3 reduce headache days (59% to 15%) Effectiveness of high-dose riboflavin in migraine
prophyloaxis: a randomized controlled trial.
Neurology 1988; 50:466-70
Morning Sickness
Ginger root (LOE 1b)250 mg powdered ginger root before meals
and bedtime (1 gm per day)Small double blinded placebo controlled
randomized trialDecreased vomiting
Obstet Gynecol 2001; 97:577-82
Morning Sickness
Vitamin B625- 50 mg 2-3 times daily
Acupressure Wrist band on P6 point
Reduced severity of nausea
Cochrane Library, Issue 2, 2002
Osteoporosis
Calcium and Vitamin D500mg Ca++ and 700 IU Vit D (LOE 1b)Better bone densityFewer fractures over 3 years (5.9% vs
12.9%)
Effect of calcium and vitamin D supplementation on bone mineral density in men and women 65 years of age or older. NEJM 1997; 337: 670-6
Menopause
Soy supplementation
60 gm soy protein daily (LOE 1b)Decreased frequency and severity of hot
flushes
The effect of dietary soy supplementation on hot flushes Ob Gyn 1998;91:6-11
Warts
PodophyllumThe rhizomes are used as a catharticResin extracted used as an irritant
Closing
Ask your patients
Ask more than once
Ask about vitamins or supplements