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An Endotoxin to replace LPSKdo2-Lipid A from Avanti®
Kdo2-Lipid AAvanti Number 699500
A new preparation of the saccharolipid glycan, Kdo2-Lipid A, is a nearly homo-geneous Re lipopolysaccharide (LPS) sub-structure with endotoxin activity equal to that of native LPS. Kdo2-Lipid A is comparable
to LPS and its activity is reduced by >103 in cells from TLR-4 deficient mice. The advantage of Kdo2-Lipid A over LPS is that it is a reproducible, defined natural product, and it
can be detected by ESI/MS at the low concentrations used to stimulate animal cells. The purity of Kdo2-Lipid A should also facilitate the structural analysis of its complexes with signaling receptors, such as TLR-4/MD2.
Phone 800-227-0651 (205-663-2494 International) or Email [email protected] details of Avanti’s selection of lipids of unparalleled purity visit www.avantilipids.com
Reference Kdo2-Lipid A of Escherichia coli, a defined endotoxin that activates macrophages via TLR-4. Raetz, C.R.H. et al. (2006) J. of Lipid Res 47:1097-111.
FROM RESEARCH TO CGMP PRODUCTION - AVANTI’S HERE FOR YOU
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The Journal of Biological ChemistryISSN 0021-9258 (print)ISSN 1083-351x (electronic)
GENERAL INFORMATION
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POSTDOCTORAL FELLOWSHIPDepartment of Dermatology, OHSU, Portland, Oregon
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A
Adachi, Hiroaki, 23240
Adams, Joseph, 23036
Aggerbeck, Martine, 23591
Akamine, Akifumi, 23275
Akkarapatumwong,Varaporn, 23205
Al-Abed, Yousef, 23089
Alexeenko, Vadim, 23655
Aljabari, Bayan, 23089
Alvarez-Barrientos,Alberto, 23044
Anastasiadis, Panos Z.,23387
Andersson, K. Kristoffer,23372
Anderton, Brian H., 23645
Andrei-Selmer, Cornelia L.,23603
Antoine, Benedicte, 23591
Aoki, Masahiro, 23532
Aprikian, Pavel, 23437
Arai, Yasuhiro, 23240
Arndt, Katja M., 23015
Atanasiu, Roxana, 23509
Atkins, William M., 23264
Auxilien, Sylvie, 23663
Awada, Mohamad, 23465
B
Bahar, Keren, 23561
Balogh, Larissa M., 23264
Banci, Lucia, 23140
Banerjee, Jayee, 23465
Bar, Jorg, 23687
Bar, Severine, 23104
Barnaby, Roxanna, 23725
Barouki, Robert, 23591
Bartoov-Shifman, Reut,23561
Bassit, Bhramdeo, 23639
Becker, Peter, 23326
Beerli, Rene, 23231
Beier, Frank, 23500
Belcastro, Marycharmain,23613
Bellamy-McIntyre, Anna K.,23104
Benoff, Brian, 23525
Berks, Ben C., 23194
Bertini, Ivano, 23140
Bezprozvanny, Ilya, 23655
Biddinger, Sudha B., 23672
Biernoth, Tanja, 23427
Bish, Rebecca A., 23184
Blackwood, David, 23081
Blatt, Thomas, 23427
Blechschmidt, Anke, 23231
Blommers, Marcel J. J.,23231
Boemke, Gerrit, 23427
Bondensgaard, Kent,23326
Brandt, Roland, 23465
Breinholt, Jens, 23326
Briscoe, David M., 23679
Bruno, Stefano, 23194
Bucala, Richard, 23447
Buga, Georgette, 23698
Bugaj, Vladislav, 23655
Bush, Craig R., 23387
Byers, Helen L., 23645
Byun, Hweejo, 23572
C
Calderon-Salinas, J. Victor,23708
Cantini, Francesca, 23140
Cao, Chunmei, 23354
Cao, Youjia, 23737
Cappello, Michael, 23447
Carlier, Marie-France,23005
Carretero-Ortega, Jorge,23708
Casey, Joseph R., 23205
Cavanaugh, Lorraine F.,23418
Chan, Andrew M., 23306
Chapron, Charles, 23591
Chauvet, Caroline, 23591
Chauvet, Genevieve,23591
Chavakis, Triantafyllos,23603
Chen, Chunlei, 23354
Chen, Kuang-Hueih, 23354
Chen, Lu, 23387
Chen, Xiaocheng, 23418
Chen, Yibang, 23447
Chen, Yuntao, 23553
Cheney, Richard E., 23725
Cheng, Heping, 23354
Cheng, Kai Fan, 23089
Cho, Yoonsang, 23447
Choi, Eun Young, 23603
Chopin, Franck, 23541
Chou, Katherine J., 23698
Chun, Wanjoo, 23410
Ciafre, Silvia Anna, 23716
Ciccotosto, Giuseppe D.,23362
Clevers, Hans C., 23532
Cohen, Shmuel E., 23672
Coutermarsh, Bonita,23725
Cramer, William A., 23163
Crichlow, Gregg V., 23089
D
Dabideen, Darrin, 23089
Daniel-Vedele, Francoise,23541
Datsenko, Kirill A., 23163
De, Mithu, 23362
Deckmyn, Hans, 23517
Della-Malva, Nunzia, 23140
De Maeyer, Bauke, 23517
De Maeyer, Marc, 23517
Deniset, Justin F., 23081
DiFedele, Lisa, 23447
Dole, Sudhanshu, 23622
Dormond, Olivier, 23679
Dou, Zhixun, 23737
Drummer, Heidi E., 23104
Duban, AndrzejJoachimiak, Mark-Eugene, 23129
Dudek, Steven M., 23284
Duncan, Michael B., 23337
Dupuis, Holly, 23500
E
Eavri, Ronen, 23402
Edelmann, Anke, 23687
Eipper, Betty A., 23362
Elias, Demetra, 23348
Elouardighi, Hasnae, 23631
Elsasser, Hans-Peter, 23427
Enoki, Norio, 23275
F
Fanara, Patrizia, 23465
Farias-Eisner, Robin, 23698
Feng, Yue, 23553
Ferreira, Gloria C., 23025
Fogelman, Alan M., 23698
Fontayne, Alexandre,23517
Forest, Claude, 23591
Fournier, Brigitte, 23231
Fu, Xiang-Dong, 23036
Fujimoto, Mitsuaki, 23240
Fukuda, Mitsunori, 23725
G
Gabrielli, Lisa, 23348
Gaemlich, Astrid, 23427
Galardi, Silvia, 23716
Gallouzi, Imed E., 23348
Garcia, Joe G. N., 23284
Gavilanes, Francisco,23044
Ge, Helen, 23698
Gebhardt, Rolf, 23672
Gehring, Kalle, 23348
Geiser, Martin, 23231
Gergely, Fanni V., 23096
Gertsberg, Zoya, 23631
Ghosh, Gourisankar, 23036
Giorda, Ezio, 23716
Giulia Farace, Maria, 23716
Glushankova, Lyuba,23655
Gojon, Alain, 23541
Goldman, Adrian, 23219
Golinelli-Pimpaneau,Beatrice, 23663
Gorbitz, Carl Henrik, 23372
Grijalva, Victor, 23698
Groettrup, Marcus, 23010
Grosjean, Henri, 23663
Grune, Tilman, 23427
Guerra, Rudy, 23387
Guo, Jianfen, 23631
Gushchin, Marina I., 23316
Gutierrez, Pablo, 23348
Gutkind, J. Silvio, 23708
H
Hagemann, Urs B., 23015
Hagopian, Jonathan,23036
Hama, Susan, 23698
Hanein, Dorit, 23316
Hanger, Diane P., 23645
Hansen, Karyn, 23725
Harper, Macha R., 23465
Harrison, Lisa M., 23447
Havens, Jennifer M., 23387
Hazelwood, Larnele, 23316
He, Donghong, 23284
Hellerstein, Marc K., 23465
Hemmings, Andrew M.,23194
Hernandez-Garcıa,Ricardo, 23708
Hernandez-Negrete,Ivette, 23708
Hersleth, Hans-Petter,23372
Hjorth, Siv A., 23326
Hoang, Thuong, 23306
Homma, Yu, 23581
Honaker, Matthew T.,23264
Honda, Jun-ya, 23275
Hou, Liming, 23264
Huang, Jing, 23253
Hubbi, Maimon E., 23572
Hueck, Rommel V., 23465
Hughson, Frederick M.,23418
Hunter, Gregory A., 23025
Husted, Kristofor H., 23465
Huynh, Nhat, 23036
Hyen Baek, Jin, 23572
I
Ieguchi, Katsuaki, 23296
Ikegawa, Shiro, 23070
Ikezawa, Kazuhiko, 23070
Inoue, Ryuji, 23117
Islinger, Markus, 23055
Iyer, Shankar S., 23147
J
Jacobson, Jeffrey R., 23284
Janik, Dorota, 23129
Johnson, Danielle E., 23205
Johnson, Gail V. W., 23410
Jones, Brian F., 23447
Jung, Tobias, 23427
K
Kahn, C. Ronald, 23672
Kallen, Joerg, 23231
Kalluri, Raghu, 23337
Kamprad, Manja, 23687
Kang, Lishan, 23326
Kanno, Eiko, 23725
Karlson, Katherine H.,23725
Kassner, Ingrid, 23010
Kataoka, Tohru, 23296
Kaznacheyeva, Elena,23655
Kern, Justin W., 23129
Keskanokwong, Thitima,23205
Khanna, Savita, 23482
Kidd, Brian, 23437
Kilpelainen, Ilkka, 23219
Kim, Kwangsoo, 23457
Kirchberger, Jurgen, 23687
Kitagawa, Teizo, 23372
Kittanakom, Saranya,23205
Kiyama, Hiroshi, 23491
Kiyoshima, Tamotsu,23275
Kleinberg, Michael E.,23284
Kneesh, Annette L., 23081
Kobatake, Yuji, 23491
Kobayashi, Ieyoshi, 23275
Kojima, Yasushi, 23532
Kokkotou, Efi, 23672
Kondo, Tatsuya, 23672
Konishi, Hiroyuki, 23491
Kozak, Kathy, 23698
Kozlov, Guennadi, 23348
Krapp, Anne, 23541
Kratzsch, Juergen, 23672
Krementsova, Elena B.,23316
Ku, Li, 23553
Kueper, Thomas, 23427
Kurose, Hitoshi, 23117
Kusner, David J., 23147
Kwong, Yuen-Kwan Amy,23447
L
Lam, Hung, 23509
Lamas, Santiago, 23044
Langford, George M.,23725
Lattmann, Rene, 23231
Lay, Chan-Sien, 23104
Lee, Terry D., 23698
Lehtio, Lari, 23219
Lejay, Laurence, 23541
Leng, Lin, 23447
Lenz, Holger, 23427
Leppanen, Veli-Matti,23219
Leroyer, Stephanie, 23591
Leskela, Tarja T., 23171
Leung, Kit-Yi, 23645
Li, Changzhong, 23253
Li, Ka Wan, 23055
Li, Yue-Ming, 23639
Liao, James C., 23698
The Journal of Biological Chemistry
AUTHOR INDEX
AUGUST 10, 2007 • VOLUME 282 • NUMBER 32 JOURNAL OF BIOLOGICAL CHEMISTRY xi
Liou, Heng-Ling, 23525
Liu, Ye V., 23572
Lobel, Peter, 23525
Lolis, Elias, 23089, 23447
Loos, Maarten, 23055
Lorberboum-Galski, Haya,23402
Luers, Georg H., 23055
Lui, HongJun, 23316
Lukasiewicz, Randall,23036
Luxon, Bruce A., 23387
M
Ma, Zhuojun, 23253
Madhusudan, S., 23622
Madsen, Dennis, 23326
Madsen, Joren C., 23679
Maerz, Anne L., 23104
Mains, Richard E., 23362
Maniar, Amudhan, 23603
Mantzoros, Christos S.,23672
Maresso, Anthony W.,23129
Markkanen, Piia M. H.,23171
Martınez-Moreno, Monica,23044
Martınez-Ruiz, Antonio,23044
Martino, Margot, 23337
Mason, Jody M., 23015
Massalini, Simone, 23716
Matentzoglu, Konstantin,23010
Matsushita, Tadashi, 23517
McDonald, Karin R., 23572
Melrose, Natalie A., 23147
Meng, Hsiang-Hui, 23698
Mercatelli, Neri, 23716
Meur, Gargi, 23096
Miao, Yunan, 23698
Migliardi, Manuele, 23140
Miller, Edmund J., 23089
Missiakas, Dominique M.,23129
Miyoshi, Hiroyuki, 23532
Mizushima, Tohru, 23240
Moreau-Marquis, Sophie,23725
Mori, Yasuo, 23117
Mozhayeva, Galina N.,23655
Muhr, Gesa-Meike, 23427
Murakami, Shinya, 23070
Myers, Michael P., 23184
N
Nagarajavel, V., 23622
Nakai, Akira, 23240
Nakao, Masahiro, 23581
Nakayama, Toru, 23581
Namba, Takushi, 23240
Namikawa, Kazuhiko,23491
Natarajan, Viswanathan,23284
Nath, Abhinav, 23264
Navab, Mohamad, 23698
Necela, Brian M., 23387
Newman, Peter J., 23603
Ng, Kei-cheuk, 23264
Nishida, Motohiro, 23117
Nishino, Tokuzo, 23581
Noguchi, Akio, 23581
O
Obeid, Lina M., 23147
Ochani, Mahendar, 23089
Odriozola, Leticia, 23306
Oehlmann, Wulf, 23473
Ogushi, Mariko, 23117
Omkvist, Diana Højmark,23326
Onohara, Naoya, 23117
Orlova, Valeria V., 23603
Osborne, Michael J., 23348
Oshima, Masanobu, 23532
Osterhout, Donna J., 23553
Ottl, Johannes, 23231
Otto, Henning, 23687
Ozawa, Yasuhiro, 23070
P
Paddock, Cathy, 23603
Pantaloni, Dominique,23005
Parinandi, Narasimham L.,23284
Park, Han-A, 23482
Park, Jinseo, 23457
Parker, Andrew K. T., 23096
Pavlov, Valentin A., 23089
Pelczer, Istvan, 23418
Pelzer, Christiane, 23010
Pendyala, Srikanth, 23284
Permi, Perttu, 23219
Petaja-Repo, Ulla E., 23171
Pierce, Grant N., 23081
Pietila, E. Maritta, 23171
Pihlajamaa, Tero, 23219
Pitson, Stuart M., 23147
Poumbourios, Pantelis,23104
Prahl, Stefanie, 23427
Preissner, Klaus T., 23603
Q
Quette, Joelle, 23591
R
Rahmouni, A. Rachid,23622
Reddy, Srinivasa T., 23698
Reithmeier, Reinhart A. F.,23205
Reyes-Cruz, Guadalupe,23708
Reynolds, C. Hugh, 23645
Rhee, Sangkee, 23457
Richard, Melanie N., 23081
Richardson, Brian C., 23418
Ridner, Gabriela, 23561
Rieder, Florian, 23337
Rizo, Josep, 23418
Roberts, Arthur G., 23264
Rodrıguez-Crespo,Ignacio, 23044
Røhr, Åsmund K., 23372
Romer, Lewis H., 23284
Ronnholm, Gunilla, 23219
Rosato, Antonio, 23140
Rosenfeldt, Hans, 23708
Rothemund, Sven, 23687
Roy, Sashwati, 23482
Rubins, Nir, 23561
Rybin, Vitalyi O., 23631
S
Sachs, Ulrich J. H., 23603
Saito, Atsushi, 23581
Saito, Masahiro, 23070
Sakai, Hidetaka, 23275
Santoni, Veronique, 23541
Santoso, Sentot, 23603
Sasaki, Nobuhiro, 23581
Sato, Yoji, 23117
Satoh, Takaya, 23296
Sauve, Veronique, 23194
Saxton, Malcolm J., 23645
Scheffner, Martin, 23010
Schellenberger, Wolfgang,23687
Schiødt, Christine Bruun,23326
Schlaeppi, Jean-Marc,23231
Schmidtke, Gunter, 23010
Schneewind, Olaf, 23129
Schneider, Gunter, 23473
Schnell, Robert, 23473
Schnetz, Karin, 23622
Schoneberg, Torsten,23687
Schunemann, Volker,23372
Seereeram, Anjan, 23645
Semenza, Gregg L., 23572
Sen, Chandan K., 23482
Shandro, Haley J., 23205
Shao, Zhuhong, 23500
Sharma, Onkar, 23163
Shen, Tao, 23354
Shikata, Keiji, 23491
Shireman, Laura M., 23264
Shrier, Alvin, 23509
Singh, Gobind, 23306
Singh, Mahavir, 23473
Singh, Rajesh K., 23010
Skopin, Anton, 23655
Sobue, Gen, 23240
Sokolov, Maxim, 23613
Sokurenko, Evgeni, 23437
Song, Hongman, 23613
Stab, Franz, 23427
Stanton, Bruce A., 23725
Steinberg, Susan F., 23631
Stock, Ann M., 23525
Strauss, Andre, 23231
Su, Weidong, 23387
Suda, Reiko, 23117
Sun, Juan, 23253
Swiatecka-Urban,Agnieszka, 23725
T
Tachibana, Taro, 23491
Takahashi, Keiko, 23275
Takahashi, Seiji, 23581
Taketo, Makoto M., 23532
Takeuchi, Koji, 23240
Talbo, Gert H., 23104
Talebian, Laleh, 23725
Tanabe, Shihori, 23117
Tanaka, Ken-Ichiro, 23240
Tang, Jian, 23354
Tang, Jun, 23737
Tanjore, Harikrishna, 23337
Tanneberger, Katrin, 23687
Taylor, Colin W., 23096
Tchesnokova, Veronika,23437
Terashima, Yoshimitsu,23070
Teschner, Thomas, 23372
Thomas, Wendy, 23437
Thompson, Christopher R.,23147
Thompson, E. Aubrey,23387
Thorner, Paul, 23205
Tian, Donghua, 23553
Tillard, Pascal, 23541
Tomkiewicz, Celine, 23591
Tomoeda, Miki, 23070
Tordjman, Joan, 23591
Tossavainen, Helena,23219
Toyosawa, Satoru, 23070
Trautwein, Alfred X., 23372
Trinchina, Elena, 23437
Trybus, Kathleen M., 23316
Tsiokas, Leonidas, 23655
Turner, Holly, 23465
Tuusa, Jussi T., 23171
U
Uchida, Takeshi, 23372
Ueda, Shuji, 23296
Ungar, Daniel, 23418
Usatyuk, Peter V., 23284
V
Vanni Frajese, Giovanni,23716
Vazquez-Prado, Jose,23708
Velazquez-Dones, Adolfo,23036
Vermeire, Jon J., 23447
Viennois, Gaelle, 23541
Vilas, Gonzalo L., 23205
Vogel, Viola, 23437
Vogt, Yvonne, 23427
Volkl, Alfred, 23055
Volkmann, Niels, 23316
W
Walbott, Helene, 23663
Walker, Michael D., 23561
Walker, Valerie E., 23509
Wang, Chunyu, 23639
Wang, Guannan, 23253
Wang, Guoyan, 23500
Wanner, Barry L., 23163
Ward, Malcolm A., 23645
Watanabe, Junji, 23698
Weiss, Timo, 23603
Welge, Vivienne, 23427
Wenck, Horst, 23427
Wesley, Jacob B., 23572
Whitelegge, Julian P.,23698
Wirth, Judith, 23541
Wittern, Klaus-Peter, 23427
Wollscheid, Hans-Peter,23010
Woods, Anita, 23500
Worsaae, Anne, 23326
Wray, Selina, 23645
Wu, Ruiying, 23129
X
Xiao, Rui-Ping, 23354
Xie, Liping, 23253
Xie, Ming, 23275
Xiong, Huabao, 23447
Xu, Sujuan, 23525
Y
Yakovenko, Olga, 23437
Yamada, Satoru, 23070
Yamashita, Eiki, 23163
Yamashita, Mayo, 23517
Yamaza, Haruyoshi, 23275
Yanagisawa, Masahiro,23387
Yang, Changqing, 23337
Yang, Xia, 23639
Yarov-Yarovoy, Vladimir,23437
Yenchitsomanus, Pa-thai,23205
Yin, Jie, 23737
Yin, Ye Ingrid, 23639
Yoneda, Shinya, 23070
Young, E. J., 23613
Z
Zakharov, Stanislav D.,23163
Zeisberg, Michael, 23337
Zhalnina, Mariya V., 23163
Zhan, Steve, 23284
Zhang, Cuizhu, 23737
Zhang, Junshun, 23025
Zhang, Rongguang, 23129
Zhang, Rongqing, 23253
Zhang, Wanrui, 23354
Zheng, Ming, 23354
Zhou, Zhuo, 23737
Zhu, Lei, 23639
Zimina, Olga, 23655
xii JOURNAL OF BIOLOGICAL CHEMISTRY VOLUME 282 • NUMBER 32 • AUGUST 10, 2007