An Approach to a Child With Oedema

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    An approach to a child with

    oedema

    Pushpa Raj Sharma

    Professor of Child HealthInstitute of Medicine

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    Oedema: accumulation excess interstitial fluid Increased hydrostatic pressure

    Acute nephritic syndromeCongestive cardiac failure

    Decreased plasma oncotic pressure

    Protein calorie malnutrition, Nephrotic syndrome; proteinloosing enteropathy

    Increased capillary leakageAllergy, sepsis, angiooedema.

    Impaired venous flowVanacaval obstruction, hepatic vein obstruction

    Impaired lymphatic flowCongenital lymphedema, Wuchereria bancrofti infection

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    Entry questions and

    threading questions

    Sensitivity

    Specificity

    Understandable

    Open ended

    Leading

    Short

    Acceptable

    Entry questions:

    Enters into the organ/system

    Threading question Enters into the specific

    aetiology.

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    Examples for formulation of questions

    Localized oedema

    Insect bite; trauma; skin infections

    Kwashiorkar (bilateral pedal)

    Superior vanacaval obstruction

    Lymphatic obstruction Orthostatic

    Generalized oedema

    Renal:periorbital; hematuria; hypertension;symptoms of collagen disease (rash, joint pain);frothy urine; symptoms of uraemia (vomiting,nausea, pallor), convulsion, low urine output.

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    Examples for formulation of questions

    Cardiac: orthopnoea, joint pain; palpitation;giddiness; fainting episodes; bluish episodes;

    Protein energy malnutrition: low calorie and

    protein in the diet for long; precipitating factors(persistent diarrhea, chronic illnesses)

    Hepatic: Jaundice; ascites; prominent abdominal

    veins; neonatal umbilical sepsis; spleenomegaly;purpura

    Collagen diseases: fever, rash, joint pain, pallor

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    First case

    4 year old girl, whorecently recovered froma sore throat, wasbrought to the OPDwith symptoms of

    swelling of bothfeet. Physicalexamination revealsedema around the eyes

    and the ankle. Aroutine urinalysisreveals the followingresults.

    The most likely diagnosis is

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    Urine examination

    Chemical/Physical AnalysisColor:YellowBlood:Moderate;Clarity:Hazy;pH:6.5

    Glucose:Negative;Protein:300mg/dL;Ketones:Negative

    Specific Gravity:1.015 ;Nitrite:Negative Microscopic Analysis

    20-50 RBC/hpf10-20 WBC/hpf

    2-5 RBC casts/hpf2-5 Granular casts/hpf

    What is the most likely diagnosis?

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    Second case 5 year male child

    Swelling first noticedaround eyes.

    No history of shortnessof breath; fever; cough;

    jaundice; umbilicalinfection; no darkcolored urine.

    Height: 110cms; Wt:

    18kg; liver notenlarged; Ascitespresent

    The most likely diagnosis is

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    Third case

    !2 year male fromPokhara; arrived aftertraveling by bus for 12hours.

    History of fever

    Upper abdominal pain

    Dark colored urine

    No past history of sorethroat, rash, joint paindiarrhea, trauma.

    Comfortably lying flat in

    bed Oral temp: 102.0

    Respiratory rate: 28.min

    Bilateral pedal edema, non

    tender

    Absence of Jaundice

    Weight: 38 Kg.

    Chest: normal Abdomen: Tender R hypo.

    No free fluid

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    Third case: Normal blood count

    Urine: routine normal Liver function: normal

    X-ray chest: normal

    What causes we have excluded?Increased hydrostatic pressure?

    Decreased plasma oncotic pressure?

    Increased capillary leakage?Impaired venous flow?

    Impaired lymphatic flow?

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    Third case: further investigation Bilateral edema and

    tender Rhypochondrium.

    Ultrasound of theabdomen:

    Thickened Gall Bladderwall

    Mucocoele

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    Third case :Final diagnosis and

    pathophysiology

    Edema: increased hydrostatic pressure dueto gravitational effect from prolonged leghanging.

    R. Hypochondrium pain and fever:cholecystitis and mucocele of gall bladder

    (ultrasound supported)

    Edema subsided on the next day after admission.

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    Fourth case

    5 year male child

    Swelling started from limb :one month

    No history of cough,

    shortness of breath,cyanosis, jaundice, darkcolored urine, umbilicalinfection.

    Persistent diarrhea +. Irritable; wt: 6 kg; Ht:

    100cms. Serum protein:1.5G/dL; Urine normal

    What is the diagnosis?

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    Fourth case 6 year female child

    Swelling both feet for10 days.

    History: shortness ofbreath off and on for1

    year, joint pain;palpitation; low urineoutput; fever with rigor

    Tachypnoea; pyrexial,propped-up; raised

    JVP, enlarged liver andspleen; urine showsRBC.

    The most likely diagnosis is