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Speaker: John Q. Public 117 March 2017
Analytik Jena AG – a Solution Provider
Launching of "Life Science“
business unit
A quarter of
a century:
Analytik
Jena
celebrates
25th
anniversary
New strong
partner: Endress+Hauser acquires
Majority interest inAnalytik Jena AG; Acquisition of UVP, LLC
Setting the course: Acquisition of "laboratory analysis technology" from
Carl Zeiss Jena and launch of business unit "Analytical Instrumen-tation"
Analytik Jena acquires
Bruker’s ICP-
MS
Business
Acquisitions: Considerable expansion of product
portfolio by integration of Biometra GmbH and stock listed CyBio AG
IPO: EUR 20 m cash
for growth story
Founded as trading company
with commercial register number 27
Analytik Jena Story
Speaker: John Q. Public 3
The birthplace of the industrial manufacturing of the first optical analytical
measuring devices is in the optical workshop of Carl Zeiss. Ernst Abbe had
delivered the basic scientific principles for their manufacturing.
17 March 2017
1990 1995 2000 2005 2009 2013 2014 2015
150 years of tradition
High Throughput Screening Tutorial SLAS
5
Overcome bottlenecks in MALDI sample plate preparation
1536 parallel pipetting – beyond just spotting
2017 Feb 07 Speaker: Swen Tyrasa
8
CyBio®-Well vario with accessories
(Photo: Analytik Jena AG)
Overcome bottlenecks in MALDI sample plate preparation
1536 parallel pipetting – beyond just spotting
Pipetting solution offering the
same speed as new Bruker
rapifleX
Fully automatic sample
preparation (‘spotting’)
“On target washing” - desalting
more than just spotting
Goals
Speaker: Swen Tyrasa2017 Feb 07
9
Analytik Jena Automation Solution for MALDI sample
preparation (Photo: Analytik Jena AG)
Overcome bottlenecks in MALDI sample plate preparation
1536 parallel pipetting – beyond just spotting
Pipetting solution offering the
same speed as new Bruker
rapifleX
Fully automatic sample
preparation (‘spotting’)
“On target washing” - desalting
more than just spotting
Walk away solution with a fully
automated plate change in 8-10
min
Precise schedule for total process
Goals
Speaker: Swen Tyrasa2017 Feb 07
10
CyBio®-Well vario 1536 MALDI sample spotting
(Photo: Analytik Jena AG)
Overcome bottlenecks in MALDI sample plate preparation
1536 parallel pipetting – beyond just spotting
10 position deck
Robot access to all positions
1536 parallel pipetting head
Exchangeable, 384 possible
Accessories
Introducing Enabling Technology
CyBio® Well vario components
Speaker: Swen Tyrasa2017 Feb 07
11
CyBio®-Well vario 1536 MALDI sample spotting
(Photo: Analytik Jena AG)
Overcome bottlenecks in MALDI sample plate preparation
1536 parallel pipetting – beyond just spotting
Ceramic or stainless steel tips
100 nl-1µl transfer
Optimized tip wash procedure
Introducing Enabling Technology
CyBio® Well vario components
Speaker: Swen Tyrasa2017 Feb 07
12
CyBio®-Well vario 1536 MALDI sample spotting
(Photo: Analytik Jena AG)
Overcome bottlenecks in MALDI sample plate preparation
1536 parallel pipetting – beyond just spotting
Matrix reservoir
With lid option
Automatic refillable
Fill level detection
Spring loaded adapter
Active drying
Introducing Enabling Technology
CyBio® Well vario components
Speaker: Swen Tyrasa2017 Feb 07
13
CyBio®-Well vario 1536 MALDI sample spotting
(Photo: Analytik Jena AG)
Overcome bottlenecks in MALDI sample plate preparation
1536 parallel pipetting – beyond just spotting
Increase quality of results due to:
Reduce salt concentration on
spots
Reduce and eliminate adducts
Increase signal, reduce noise
Expand life time of ion optics
Introducing Enabling Technology
„on target washing“ – desalting
Speaker: Swen Tyrasa2017 Feb 07
Workflow „sandwich“ matrix/assay/matrix 100nl
Overcome bottlenecks in MALDI sample plate preparation
1536 parallel pipetting – beyond just spotting
Speaker: Swen Tyrasa 142017 Feb 07
1 Matrix transfer to MALDI sample plate
2 Active drying and tip wash (parallel)
3 Assay transfer to MALDI sample plate
4 Active drying and tip wash (parallel)
5 Matrix transfer to MALDI sample plate
6 Active drying and tip wash (parallel)
7 Optional „on target washing“
8 Export plate to rapifleX™
Workflow in action
Overcome bottlenecks in MALDI sample plate preparation
1536 parallel pipetting – beyond just spotting
15
Analytik Jena Automation system - Tailored for your needs
Speaker: Swen Tyrasa2017 Feb 07
Robust
Precise
Modular
Scalable
Ergonomic
Overcome bottlenecks in MALDI sample plate preparation
1536 parallel pipetting – beyond just spotting
16
Timing and throughput Sample prep less than 10 minutes per plate
1.000.000 samples in less than 5 days
Perfect match to rapifleX™ analysis time
Speaker: Swen Tyrasa2017 Feb 07
17
Overcome bottlenecks in MALDI sample plate preparation
1536 parallel pipetting – beyond just spotting
Summary
Enable Mass Spec based screening in primary uHTS
Full automatic sample preparation
pipetting and active drying
384 / 1536 well assay plate format
1536 sample plate format and 3072
Desalting function
Speaker: Swen Tyrasa2017 Feb 07
Perfect match to rapifleX™ analysis time
18
Overcome bottlenecks in MALDI sample plate preparation
1536 parallel pipetting – beyond just spotting
Acknowledgement
Melanie Leveridge
Carl Haslam
Peter Marshall
Neil Hardy
Meike Hamester
Jens Fuchser
Franz Mayer
Adrian Siemers
Debra Conway
Speaker: Swen Tyrasa2017 Feb 07
