ANANIAS A. ESCALANTE Professor, School of Life … · ANANIAS A. ESCALANTE Professor, School of Life Sciences Arizona State University CENTER FOR EVOLUTIONARY MEDICINE AND INFORMATICS,

ANANIAS A. ESCALANTE Professor, School of Life Sciences

Arizona State University

CENTER FOR EVOLUTIONARY MEDICINE AND INFORMATICS, THE BIODESIGN INSTITUTE & PHONE: (480) 965-3739 SCHOOL OF LIFE SCIENCES FAX: (480) 965-6899 ARIZONA STATE UNIVERSITY E-MAIL: [email protected] PO BOX 874501 SKYPE: VIVAXMAL TEMPE AZ 85287-4501, USA WEBPAGE:http://sols.asu.edu/faculty/aescalante.php

PROFESSIONAL PROFILE

I have built an international research program in ecology and evolution of infectious diseases. My program focuses on establishing bridges among anthropological, epidemiological, ecological, and evolutionary biology perspectives by interpreting genetic patterns from pathogens and integrating them with environmental or epidemiologic information. I have experience managing complex research and training projects that demand strong international collaborations.

EDUCATION

- POSTDOCTORAL FELLOW,Division of Parasitic Diseases, Centers for Disease Control and Prevention (CDC), Atlanta, GA. (1995-1997).

- PH.D. IN BIOLOGICAL SCIENCES, Dept. of Ecology and Evolutionary Biology, University of California, Irvine. (1995). Origin and Evolution of the genus Plasmodium.

- M.SC. IN BIOLOGICAL SCIENCES, USB, Caracas, Venezuela (1989). Dissertation: Study of an arthropod community associated with the fermentation of Pilosocereus lanoginosus.

- LICENCIADO IN BIOLOGY,Universidad Simón Bolívar (USB), Caracas, Venezuela (1985).

PROFESSIONAL AND ACADEMIC EXPERIENCE MAY/10-PRESENT CORE FACULTY, CENTER FOR EVOLUTIONARY MEDICINE AND INFORMATICS, THE

BIODESIGNINSTITUTE AT ARIZONA STATE UNIVERSITY.

JUL/09-PRESENT PROFESSOR, SCHOOL OF LIFE SCIENCES, ARIZONA STATE UNIVERSITY.

APR/97-PRESENT VISITING SCIENTIST, CENTRO DE CÁLCULO CIENTÍFICO,UNIVERSIDAD DE LOS ANDES, VENEZUELA.

JAN/07-JUN/09 Adjunct Faculty, Department of Biology, Emory University, Atlanta, USA.

Jan/05-July/09 Associate Professor, School of Life Sciences, Arizona State University.

Jun/05-Jun/09 Permanent Member of the Genetic Variation and Evolution Study Section, Center for Scientific Review, National Institutes of Health (2005-2009).

May/04-May/07 Coordinator Latin American Network on Molecular Epidemiology (LANMEp), United Nations University- Biotechnology for Latin America and the Caribbean (BIOLAC) program.

Page 2 ESCALANTE, A. A.

Sep/97-Sep/06 Visiting Scientist, Division of Parasitic Diseases, Centers for Disease Control and Prevention, Atlanta, USA.

Aug/98-Dec/04 Adjunct Faculty, Department of Biology, PBEE, Emory University, Atlanta, USA.

Apr/98-Dec/04 Researcher (Associate III), Centro de Ecología, Instituto Venezolano de Investigaciones Científicas (IVIC), Caracas, Venezuela.

ACADEMIC AWARDS/FELLOWSHIPS/HONORS

- National Center for Zoonotic, Vector-borne, and Enteric Diseases Award, Public Health Epidemiology and Laboratory Research as part of the Sulfadoxine-Pyrimethamine Team of the Malaria Branch (2008).

- Researcher Promotion Program (Programa de Promoción al Investigador), FONACIT-Venezuela, N° 3060 (1997-2004).

- “Pro Salud” award, shared with Dr. Raúl Isea (1999), Cámara Venezolana de Fabricantes de Cerveza, Venezuela.

- TALVEN program, Venezuelan Embassy before UNESCO (1997).

- Resident Postdoctoral Research Fellowship of the American Society for Microbiology (ASM), Centers for Disease Control and Prevention, Atlanta, GA. (1995- 1997).

- Cátedra Gran Mariscal de Ayacucho, Venezuela, August (1996).

- Sigma Xi Scientific Society, (1995).

- Fellowship, Consejo Nacional de Ciencia y Tecnología (CONICIT)- Inter-American Development Bank. (1993-1994).

- Tuition fellowship, University of California- Latin American Scholarship Program of America Universities (LASPAU) (1991-1992).

- Fellowship, Fundación Gran Mariscal de Ayacucho, Venezuela. (1989-1992).

RESEARCH INTERESTS

I am studyinghow host switches may lead to molecular adaptations in parasites/pathogens and how the demographic history of parasite/pathogen populations affects adaptive mutations such as those involved in drug resistance. My current projects are: i) the origin and spread of drug resistance in P. falciparum, ii) evolutionary history of P. vivax and related non-human malarial parasites, iii)the translation of evolutionary biology concepts into malaria control programs.

GRANTS: ACTIVERESEARCH SUPPORT:

TITLE: “EVOLUTION OF PLASMODIUM VIVAX AND ASIAN MACAQUE MALARIAS”, Project NIH/NIGMS R01GM080586 to A. Escalante as PI, 9/1/2008-8/31/2013 (5 years), total award: $1,242, 898.In collaboration with Lisa Jones-Engel (U. of Washington, UW) and Liwang Cui (Pennsylvania State University, PSU) as investigators.International collaborators in Afghanistan, Brazil, Cambodia, Colombia, China, Honduras, Indonesia, Korea, Madagascar, Malaysia,Pakistan, Peru, Singapore, Thailand, Turkey, and Venezuela. TITLE: “EVOLUTION AND EMERGENCE OF SIMIAN RETROVIRUSES IN SOUTH ASIA”, Project NIH/NIAID R01AI078229 (Multiple Principal Investigators) to A. Escalante as the ASU-PI9/1/2008-8/31/2013 (5


years). Total award: $3,630,175. Collaborators:Lisa Jones-Engel (UW), Nicholas W. Lerche (UC Davis), and Maxine L Linial (Fred Hutchinson Cancer Research Center). International collaborators in Bangladesh and Singapore. TITLE: “INTERNATIONAL CENTER OF EXCELLENCE FOR MALARIA RESEARCH: LATIN AMERICAN CENTER FOR MALARIA RESEARCH AND CONTROL”, project NIH 1U19AI089702. Principal Investigator:Socrates Herrera-Valencia, M.D. Universidad del Valle, Cali, Colombia. 07/01/2010- 06/30/2017. Direct cost for A. Escalante as investigator: $615,539.International collaborators in: Colombia, Honduras, Panamá, and Perú. TITLE: “INTERNATIONAL CENTER OF EXCELLENCE FOR MALARIA RESEARCH: MALARIA EVOLUTION IN SOUTH ASIA”, projectNIH U19AI089688. Principal Investigator: Pradipsinh Rathod, PhD. University of Washington, Seattle. 07/01/2010- 06/30/2017.

COMPLETED GRANTS:

TITLE: “A GLOBAL COMPARATIVE STUDY OF THE EVOLUTION OF ANTIMALARIAL DRUG RESISTANCE”, National Institute of Health (NIH), project NIH/NIGMS R01GM084320 to A. Escalante as Principal Investigator (PI), 6/1/2008-4/31/2013 (5 years), total award: $1,434,067. In collaboration with Drs. Yuseob Kim (ASU), Jesse Taylor (ASU), Christopher Plowe (U. of Maryland), and David Smith (U. of Florida) as investigators. International collaborators in Cameroon, Colombia, Indonesia, Kenya, Mali, Malawi, Peru, and Venezuela. TITLE: “BAYESIAN MODELS FOR DETECTING SELECTION IN MALARIA GENES”, project NIH/NIGMS grant R01GM072003 to Raquel Prado, UC Santa Cruz is the Principal Investigator with A. Escalante as subcontracted investigator, 4/1/2004-3/31/2010. As investigator, I assist Dr. Prado in evolutionary genetics and provide her suitable data sets for testing the models that she is developing. TITLE: “MOLECULAR EVOLUTION OF P. FALCIPARUM AND P. VIVAX”, project NIH/NIGMS R01GM60740 to A. Escalante as PI. 2/2000- 1/2007.(Total award $598,057). TITLE:“LATIN AMERICAN NETWORK ON MOLECULAR EPIDEMIOLOGY (LANMEP)”. Sponsored by the United Nations University, BIOLAC program. 5/2004 - 8/2006. A. Escalante as PI.(Total award $90,000). I organized workshops in Molecular Epidemiology for Latin-American Students. TITLE: “RED NACIONAL DE ANÁLISISGENÉTICO POBLACIONAL, SISTEMÁTICA MOLECULAR Y BIOLOGÍA INTEGRATIVA".(A national network for population genetics, molecular systematics, and integrative biology). Project started on 1/1999- 12/2004. Project G97000634 sponsored by Consejo Venezolano de Investigaciones Científicas (CONICIT), Venezuela. A. Escalante as PI.(Total award $300,000). TITLE: “ESTUDIO DE LA VARIABILIDAD GENÉTICA DE PLASMODIUM VIVAX EN VENEZUELA: DESARROLLO DE HERRAMIENTAS PARA ESTUDIOS EPIDEMIOLÓGICOS Y DE VARIABILIDAD ANTIGÉNICA”(Assessing the genetic diversity of Plasmodium vivax in Venezuela). Project S12000000537 sponsored by CONICIT, Venezuela. 1/2001- 12/2004.A. Escalante as PI.(Total award $90,000). TITLE: “GENÉTICA DE LA CONSERVACIÓN DE MAMÍFEROS Y REPTILES DE VENEZUELA” (Conservation genetics of mammals and reptiles in Venezuela)Project 98-003413 from CONICIT to M. Aguilera, USB as PI and the Wildlife Conservation Society toDr. I. Goldstein as PI, ended 1/2005.I provided basic expertise in evolutionary genetics that had applications in conservation. TITLE: “MOLECULAR EPIDEMIOLOGY NETWORK IN MALARIA”, CDC intramural, to Venkatachalam Udhayakumar of the Malaria Branch as Principal Investigator with A. Escalante as Investigator, 5/2011.


PEER REVIEWED PUBLICATIONS, TOTAL 110 JOURNAL ARTICLES (NAMES UNDERLINED ARE UNDERGRADUATE OR GRADUATE STUDENTS):

1. Taylor JE*, Pacheco MA*, Bacon DJ, Beg MA, Dantas-Machado RL, Fairhurst RM, Herrera S, Kim JY, Menard D, Póvoa MM, Villegas L, Mulyanto, Snounou G, Cui L, Zeyrek FY, Escalante AA (in press) The evolutionary history of Plasmodium vivax as inferred from mitochondrial genomes: parasite genetic diversity in the Americas. Mol Biol Evol.*=co-first author

2. Feeroz MM, Soliven K, Small CT, Engel GA, Pacheco MA, Yee JL, Wang X, Hasan MK, Oh G, Levine KL, Rabiul Alam SM, Craig KL, Jackson DL, Lee E, Barry PA, Lerche NW, Escalante AA, Matsen IV FA, Linial ML, Jones-Engel L (2013). Population dynamics of rhesus macaques and associated foamy virus in Bangladesh. Emerging Microbes & Infections (2013) 2, e29

3. Mantilla-Granados JS, Matta NE, Pacheco MA, Escalante AA, Gonzalez AD, Moncada LI.(in press) identification of Plasmodium (haemamoeba) lutzi (lucena, 1939) from Turdus fuscater (great thrush) in colombia. J Parasitol.

4. Griffing SM, Rachid Viana GM, Mixson-Hayden T, Sridaran S, Alam MT, Macedo de Oliveira A, Barnwell JW, Escalante AA, Povoa MM, Udhayakumar V (2013) Historical shifts in Brazilian P. falciparum Population Structure and drug resistance alleles. PLoS One. 8: e58984.

5. Dias S, Wickramarachchi T, Sahabandu I, Escalante AA, Udagama PV (2013). Population Genetic Structure of the Plasmodium vivax Circumsporozoite Protein (Pvcsp) in Sri Lanka. Gene. 518:381-387.

6. Patel JC, Oberstaller J, Xayavong M, Narayanan J, Debarry JD, Srinivasamoorthy G, Villegas L, Escalante AA, Dasilva A, Peterson DS, Barnwell JW, Kissinger JC, Udhayakumar V, Lucchi NW (2013). Real-Time Loop-Mediated Isothermal Amplification (RealAmp) for the Species-Specific Identification of Plasmodium vivax. PLoS One. 8:e54986.

7. Carlton JM, Das A, Escalante AA (2013). Genomics, population genetics and evolutionary history of Plasmodium vivax. Advances in Parasitology 81:203-222.

8. Schneider KA and Escalante AA (2013) Fitness components and natural selection: why are there different patterns on the emergence of drug resistance in Plasmodium falciparum and Plasmodium vivax? Malaria J. 12:1.

9. Chenet SM, Schneider KA, Villegas L, Escalante AA(2012). Local population structure of Plasmodium: impact on malaria control and elimination. Malaria J. 11:412.

10. Snounou G, Escalante A, Kasenene J, Rénia L, Grüner AC, Krief S (2012). Malaria in hominids [Article in French]. Bull Acad Natl Med 195:1945-1954.

11. Tachibana S, Sullivan SA, Kawai S, Nakamura S, Kim HR , Goto N, Arisue N, Palacpac NMQ, Honma H, Yagi M, Tougan T, Katakai Y, Kaneko O, Mita T, Kita K, Yasutomi Y, Sutton PL, Shakhbatyan R, Horii T, Yasunaga T, Barnwell JW, Escalante AA, Carlton JM, Kazuyuki K. (2012) Plasmodium cynomolgi genome sequences provide insight into Plasmodium vivax and the monkey malaria clade. Nature Genetics 44:1051-1055.

12. Neafsey DE, Galinsky K, Jiang RHY, Young L, Sykes SM, Saif S, Gujja S, Goldberg JM, Young S, Zeng Q, Chapman SB, Dash AP, Anvikar AR, Sutton PL, Birren BW, Escalante AA, Barnwell JW, Carlton JM (2012). The malaria parasite Plasmodium vivax exhibits greater genetic diversity than Plasmodium falciparum. Nature Genetics 44:1046-1050.

13. Pacheco MA, Reid MJ, Schillaci MA, Lowenberger CA, Galdikas BM, Jones-Engel L, Escalante AA (2012).The origin of malarial parasites in orangutans. PLoS One. 7:e34990.


14. Pacheco, Elango AP, Rahman AA, Fisher D, Collins WE, Barnwell JW, Escalante AA(2012). Extended Evidence of Purifying Selection on Merozoite Surface Protein 8 (MSP8) and 10 (MSP10) in Plasmodium spp. Infection, Genetics and Evolution, 12:978-986.

15. McCollum AM, Schneider KA, Griffing SM, Zhou Z, Kariuki S, ter Kuile F, Shi YP, Slutsker L, Lal AA, Udhayakumar V, Escalante AA(2012). Differences in selective pressure on dhps and dhfr drug resistant mutations in western Kenya. Malaria J, 11:77.

16. Chenet SM, Tapia LL, Escalante AA, Durand S, Lucas C, Bacon DJ (2012). Genetic diversity and population structure of genes encoding vaccine candidate antigens of Plasmodium vivax. Malaria J,11:68.

17. Miao M, Yang Z, Patch H, Huang Y, Escalante AA, Cui L (2012). Plasmodium vivax populations revisited: mitochondrial genomes of temperate strains in Asia suggest ancient population expansion. BMC Evolutionary Biology, 12:22.

18. Narayanasamya K, Cheryb L, Basuc A, Duraisingh MT, Escalante AA, Fowble J, Guler JL, Herricks T, Kumar A, Majumder P, Maki J, Mascarenhas A, Rodrigues J, Roy B, Sen S, Shastri J, Smith J, Valecha N, White J, Rathod PK (2012). Malaria Evolution in South Asia: Knowledge for Control and Elimination. Acta Tropica 121:256-266.

19. Rawasia WF, Sridaran S, Patel JC, Abdallah J, Ghanchi NK, Barnwell JW, Escalante AA, Udhayakumar V, Beg MA (2012). Genetic backgrounds of the Plasmodium falciparum chloroquine resistant transporter (pfcrt) alleles in Pakistan. Infect Genet Evol. 12:278-281.

20. Arevalo-Herrera M, Quiñones ML, Guerra C, Céspedes N, Giron S, Ahumada M, Piñeros JG, Padilla N, Terrientes Z, Rosas A, Padilla JC, Escalante AA, Beier JC, Herrera S. (2012) Malaria in selected non-Amazonian countries of Latin America. Acta Tropica 121:303-314.

21. Pacheco MA, Battistuzzi FU, Junge RE, Cornejo OE, Williams CV, Landau I, Rabetafika L, Snounou G, Jones-Engel L, Escalante AA (2011). Timing the origin of human malarias: the lemur puzzle. BMC Evolutionary Biology. 11:299.

22. Dias S, Somarathna M, Manamperi A, Escalante AA, Gunasekera AM, Udagama-Randeniya PV (2011). Evaluation of the genetic diversity of Domain II of Plasmodium vivax Apical Membrane Antigen 1 (PvAMA-1) and the ensuing strain-specific immune responses in patients from Sri Lanka. Vaccine. 29:7491-7504.

23. Pacheco MA, Escalante AA, Garner MM, Bradley GA, Aguilar RF. (2011) Haemosporidian infection in captive masked bobwhite quail (Colinus virginianus ridgwayi), an endangered subspecies of the northern bobwhite quail. Vet Parasitol. 182:113-120.

24. Premaratne PH, Aravinda BR, Escalante AA, Udagama PV. (2011) Genetic diversity of Plasmodium vivax Duffy Binding Protein II (PvDBPII) under unstable transmission and low intensity malaria in Sri Lanka. Infect Genet Evol. 11:1327-1339.

25. Griffing SM, Mixson-Hayden T, Sridaran S, Alam MT, McCollum AM, Cabezas C, Quezada WM, Barnwell JW, Macedo De Oliveira A, Lucas C, Arrospide N, Escalante AA, Bacon DJ, Udhayakumar V. (2011) South American Plasmodium falciparum after the malaria eradication era: clonal population expansion and survival of the fittest hybrids. Plos One 6 (9) e23486.

26. Demas A, Oberstaller J, Debarry J, Lucchi NW, Srinivasamoorthy G, Sumari D, Kabanywanyi AM, Villegas L, Escalante AA, Kachur SP, Barnwell JW, Peterson DS, Udhayakumar V, Kissinger JC. (2011) Applied Genomics: Data Mining Reveals Species-Specific Malaria Diagnostic Targets More Sensitive than 18S rRNA. J Clin Microbiol. 49:2411-2418.

27. Pacheco MA, Battistuzzi FU, Lentino M, Aguilar R, Kumar S, Escalante AA (2011) Evolution of modern birds revealed by Mitogenomics: timing the radiation and origin of major orders. Mol Biol Evol. 28:1927-1942.


28. Valderrama-Aguirre A, Zúñiga-Soto E, Mariño-Ramírez L, Moreno LA, Escalante AA, Arévalo-Herrera M, Herrera S. (2011) Polymorphism of the Pv200L Fragment of Merozoite Surface Protein-1 of Plasmodium vivax in Clinical Isolates from the Pacific Coast of Colombia. Am J Trop Med Hyg 84: 64-70.

29. Hernández-Martínez MA, Escalante AA, Arévalo-Herrera M, Herrera S (2011) Antigenic Diversity of the Plasmodium vivax Circumsporozoite Protein in Parasite Isolates of Western Colombia. Am J Trop Med Hyg 84: 51-57.

30. Dias S, Longacre S, Escalante AA, Udagama-Randeniya PV (2011) Genetic diversity and recombination at the C-terminal fragment of the merozoite surface protein-1 of Plasmodium vivax (PvMSP-1) in Sri Lanka. Infect Genet Evol. 11:145-156.

31. Alam MT, Vinayak S, Congpuong K, Wongsrichanalai C, Satimai W, Slutsker L, Escalante AA, Barnwell JW, Udhayakumar V (2011) Tracking origins and spread of sulfadoxine-resistant Plasmodium falciparum dhps alleles in Thailand. Antimicrob Agents Chemother. 55:155-164.

32. Datta S, Prado R, Rodriguez A, Escalante AA (2010) Characterizing molecular adaptation: a hierarchical approach to assess the selective influence of amino acid properties. Bioinformatics 26:2818-2825.

33. Tanabe K, Mita T, Jombart T, Eriksson A, Horibe S, Palacpac N, Ranford-Cartwright L, Sawai H, Sakihama N, Ohmae H, Nakamura M, Ferreira MU, Escalante AA, Prugnolle F, Björkman A, Färnert A, Kaneko A, Horii T, Manica A, Kishino H, Balloux F (2010) Plasmodium falciparum accompanied the human expansion out of Africa. Curr Biol. 20:1283-1289.

34. Pacheco MA, Ryan E, BascoL, Poe A,UdhayakumarV, CollinsWE, Escalante AA (2010) Evidence for negative selection on the gene encoding rhoptry -associated protein 1 (RAP-1) in Plasmodium spp. Infection, Genet. Evol. 10:655-661.

35. Sutherland CJ, Tanomsing N, Nolder D, Oguike M, Jennison C, Pukrittayakamee S, Dolecek C, Hien TT, do Rosário V, Arez AP, Pinto J, Michon P, Escalante AA, Nosten F, Burke M, Lee R, Blaze M, Otto TD, Barnwell J, Pain A, Williams J, White NJ, Day NPJ, Snounou G, Lockhart PJ, Chiodin PL, Imwong M, Polley SD (2010) The human malaria parasite Plasmodium ovale occurs globally as two non-recombining sympatric species. J. Inf. Dis. 201:1544-1550.

36. Vinayak S, Alam T, Sem R, Shah NK, Susanti AI, Lim P, Muth S, Maguire JD, Rogers WO, Fandeur T, Barnwell JW, Escalante AA, Wongsrichanalai C, Ariey F, Meshnick SR, Udhayakumar V (2010) Multiple genetic backgrounds of the amplified Plasmodium falciparum multidrug resistance (pfmdr1) gene and selective sweep of 184F mutation in Cambodia. J. Inf. Dis. 201:1551-1560.

37. Vinayak S, Md Tauqeer A, Mixson-Hayden T, McCollum AM, Sem R, Shah NK, Lim P, Muth S, Rogers WO, Fandeur T, Barnwell JW, Escalante AA, Wongsrichanalai C, Ariey F, Meshnick SR, Udhayakumar V (2010) Origin and Evolution of Sulfadoxine Resistant Plasmodium falciparum. Plos Pathogen. 6:e1000830.

38. Griffing S, Syphard L, Sridaran S, McCollum AM, Mixson-Hayden T, Vinayak S, Villegas L, Barnwell JW, Escalante AA, Udhayakumar V (2010) Pfmdr1 amplification and fixation of chloroquine resistant pfcrt alleles in Venezuela. Antimicrob Agents Chemother. 54:1572-1579.

39. Krief S*, Escalante AA*&, Pacheco MA, Mugisha L, André C, Halbwax M, Fischer A, Krief JM, Kasenene J, Crandfield M, Cornejo OE, Chavatte JM, Lin C, Letourneur F, Charlotte A Grüner CA, McCutchan T, Rénia L, Snounou G& (2010) The malaria parasite Plasmodium falciparum originated in African Apes and occurs in bonobo. Plos Pathogen 6:e1000765 *=co-first author, &= co-corresponding author

40. Takala SL, Coulibaly D, Thera MA, Niangaly A, Batchelor A, Cummings MP, Escalante AA, Ouattara A, Traoré K, Djimdé AA, Doumbo OK, Plowe CV (2009) Extreme Polymorphism in a Vaccine Antigen and Risk of Clinical Malaria: Vaccine Development Implications. Science Translational Medicine. 1(2):2ra5.


41. Escalante AA, Smith D, Kim Y (2009) The dynamic of mutations associated with antimalarial drug resistance in Plasmodium falciparum. Trends in Parasitology. 25:557-563.

42. Chowell G, Munayco-Escate C, Escalante AA, McKenzie FE (2009) The Spatial and temporal patterns of P. falciparum and P. vivax malaria in Peru: 1994-2006. Malaria J. 8:142.

43. Perrone TM, Gonzatti MI, Villamizar G, Escalante A, Aso PM. (2009) Molecular profiles of Venezuelan isolates of Trypanosoma sp. by random amplified polymorphic DNA method. Vet Parasitol. 161:194-200.

44. Vinayak S, Rathore D, Kariuki S, Slutsker L, Shi YP, Villegas L, Escalante AA, Udhayakumar V (2009) Limited genetic variation in the Plasmodium falciparum heme detoxification protein (HDP). Infect Genet Evol. 9:286-289.

45. Bacon DJ, McCollum AM, Griffing SM, Salas C, Soberon V, Santolalla M, Haley R, Tsukayama P, Lucas C, Escalante AA, Udhayakumar V (2009) Dynamics of malaria drug resistance patterns in the Amazon basin region following changes in national treatment policy for uncomplicated malaria. Antimicrob Agents Chemother. 53:2042-2051.

46. Carlton JM, Escalante AA, Neafsey D, Volkman SK (alphabetical order) (2008) Comparative evolutionary genomics of human malaria parasites. Trends Parasitology. 24:545-550.

47. McCollum AM, Basco LK, Tahar R, UdhayakumarV, Escalante AA (2008) Hitchhiking and selective sweeps of Plasmodium falciparum sulfadoxine and pyrimethamine resistant alleles in a population from central Africa. Antimicrob Agents Chemother. 52:4089-4097.

48. Chenet SM, Branch OH, Escalante AA, Lucas CM, Bacon DJ (2008) Genetic diversity of vaccine candidate antigens in Plasmodium falciparum isolates from the Amazon basin of Peru. Malaria J. 7:93.

49. Nishimoto Y, Arisue N, Kawai S, Escalante AA, Horii T, Tanabe K, Hashimoto T (2008) Evolution and phylogeny of the heterogeneous cytosolic SSU rRNA genes in the genus Plasmodium. Mol Phylogenet Evol. 47:45-53.

50. Hamel MJ, Poe A, Bloland P, McCollum A, Zhou Z, Shi YP, Ouma P, Otieno K, Vulule J, Escalante AA, Udhayakumar V, Slutsker L (2008) Dihydrofolate reductase I164L mutations in Plasmodium falciparum isolates: clinical outcome of 14 Kenyan adults infected with parasites harboring the I164L mutation. Trans R Soc Trop Med Hyg. 102:338-345.

51. Prado R, Merl D, Escalante AA (2008) Assessing the effect of selection at the amino acid level in malaria antigen sequences via Bayesian generalized linear models. JASA, Applications & Case Studies Section. 103: 1496-1507.

52. Zhou Z, Griffing SM, de Oliveira AM, McCollum AM, Quezada WM, Arrospide N, Escalante AA, Udhayakumar V. (2008) Decline in sulphadoxine-pyrimethamine resistant alleles after change in drug policy in the Amazon region of Peru. Antimicrob Agents Chemother. 52:739-741.

53. Tanabe K, Escalante AA, Sakihama N, Honda M, Arisue N, Horii T, Culleton R, Hayakawa T, Hashimoto T, Longacre S, Pathirana S, Handunnett S, Kishino H (2007) Recent independent evolution of msp1 polymorphism in Plasmodium vivax and related simian malaria parasites. Molecular Biochemical Parasitology, 156:74-79.

54. McCollum AM, Mueller K, Villegas L, Udhayakumar V, Escalante AA (2007) Common Origin and Fixation of Plasmodium falciparum dhfr and dhps Mutations Associated with Sulfadoxine-Pyrimethamine Resistance in a Low-Transmission Area in South America. Antimicrob Agents Chemother. 51:2085-2091.

55. Pacheco MA, Poe AC, Collins WE, Lal AA, Tanabe K, Kariuki SK, Udhayakumar V, Escalante AA (2007). A comparative study of the genetic diversity of the 42 kDa fragment of the merozoite surface protein 1 in Plasmodium falciparum and P. vivax. Infection, Genetics and Evolution. 7:180-187.


56. Zhou Z, Poe AC, Limor J, Grady KK, Goldman I, McCollum AM, Escalante AA, Barnwell JW, Udhayakumar V (2006) Pyrosequencing-a high-throughput method for detecting single nucleotide polymorphisms (SNPs) in the dihydrofolate reductase and dihydropteroate synthetase genes of Plasmodium falciparum. Jounal of Clinical Microbiology, 44:3900-3910.

57. Cornejo OE, Escalante AA (2006) The origin and age of Plasmodium vivax. Trends Parasitology, 22:558-563.

58. McCollum AM, Poe AC, Hamel M, Huber C, Zhou Z, Shi YP, Ouma P, Vulule J, Bloland P, Slutsker L, Barnwell JW, Udhayakumar V, Escalante AA (2006) Antifolate resistance in Plasmodium falciparum: multiple origins and identification of novel dhfr alleles. Journal of Infectious Diseases. 194:189-197.

59. Takala SL, Escalante AA, Branch OH, Kariuki S, Biswas S, Chaiyaroj SC, Lal AA (2006) Genetic diversity in the Block 2 region of the Merozoite Surface Protein 1 (MSP-1) of Plasmodium falciparum: selection and convergence in fragment size polymorphism. Infection, Genetics and Evolution. 6:417-424.

60. Perrone TM, Garrizzo J, Roschman-González A, Tejero F, Escalante A, Aso PM (2006) Susceptibility of different mouse strains to experimental infection with a Venezuelan isolate of Trypanosoma evansi. Journal of Protozoology Research. 16, 1-8.

61. Mascorro CN, Zhao K, Khuntirat B, Sattabongkot J, Yan G, Escalante AA, Cui L (2005) Molecular Evolution and Intragenic Recombination of the Merozoite Surface Protein MSP-3 from the Malaria Parasite Plasmodium vivax in Thailand. Parasitology, 131:25-35.

62. Escalante AA, Cornejo OE, Freeland DE, Poe AC, Durrego E, Collins WE, Lal AA (2005) A monkey's tale: The origin of Plasmodium vivax as a human malaria parasite. Proceedings of the National Academy of Sciences USA, 102: 1980-1985.

63. Tanabe K, Sakihama N, Hattori T, Ranford-Cartwright L, Goldman I, Escalante AA, Lal AA (2004) Genetic Distance in Housekeeping Genes Between Plasmodium falciparum and Plasmodium reichenowi and within P. falciparum. Journal Molecular Evolution, 59: 687–694.

64. Escalante AA, Cornejo OE, Rojas A, Udhayakumar V, Lal AA. (2004) Assessing natural selection in malarial parasites. Trends Parasitology, 20: 388-395.

65. Basco L, Tahar R., Escalante AA (2004) Molecular epidemiology of malaria in Cameroon: polymorphisms of the Plasmodium falciparum merozoite surface antigen-2 gene in isolates from symptomatic patients. American Journal of Tropical Medicine and Hygiene, 70: 238-244.

66. González JA, Trujillo L, Escalante A (2003) Intrinsic chaos and external noise in population dynamics. Physica A, 324:723-732.

67. Cui L, Escalante AA, Imwong M, Snounou G (2003) The Genetic Diversity of Plasmodium vivax Populations. Trends in Parasitology, 19: 220-226.

68. Moscarella RA, Aguilera M, Escalante AA (2003) Phylogeography, population structure, and implications for conservation of white-tailed deer (Odocoileus virginianus) in Venezuela. Journal of Mammalogy, 84: 1300–1315.

69. Goncalvez AP, Escalante AA, Pujol FH, Ludert JE, Tovar D, Salas RA, Liprandi F (2002) Diversity and Evolution of the envelope gene of Dengue virus Type I. Virology, 303:110-119.

70. Escalante AA, GrebertHM, Isea R, Goldman IF, Basco L, Magris M, Biswas S, Kariuki S, Lal AA (2002) A study of genetic diversity in the gene encoding the circumsporozoite protein (CSP) of Plasmodium falciparum from different transmission areas. Molecular and Biochemical Parasitology, 125: 83-90.

71. Takala S, Branch O, Escalante AA, Kariuki S, Wootton J, Lal AA (2002) Evidence for intragenic recombination in P. falciparum: identification of a novel allele family in block 2 of merozoite surface protein-1. Molecular and Biochemical Parasitology, 125: 163-171.


72. Kedzierski L, Escalante AA, Isea R, Black CG, Barnwell JW, Coppel RL (2002) Phylogenetic Analysis of the genus Plasmodium based on the gene encoding adenylosuccinate lyase. Infection, Genetics and Evolution, 1: 297-301.

73. Escalante AA, Grebert HM, Chaiyaroj SC, Riggione F, Biswas S, Nahlen BL, Lal AA (2002) Polymorphism in the gene encoding the Pfs48/45 antigen of Plasmodium falciparum XI Asembo Bay Cohort Project. Molecular Biochemestry and Parasitology, 119:17-22.

74. Monteiro FA, EscalanteAA, BeardCB (2001) The Application of Molecular Tools in Triatomine Systematics: A Public Health Perspective. Trends in Parasitology, 17:344-347.

75. EscalanteAA, GrebertHM, ChaiyarojSC, MagrisM, BiswasS, NahlenBL, Lal, AA (2001) Polymorphism in the gene encoding the Apical Membrane Antigen-1 (AMA-1) of Plasmodium falciparum VI Asembo Bay Cohort Project. Molecular and Biochemical Parasitology, 113: 279-287.

76. Romano E, Cesari I, Escalante A, Liprandi F, O'Daly JA, Perez A, TakiffH (2000) Overview of Some Biomedical Research Projects in Tropical Medicine Conducted at the Instituto Venezolano de Investigaciones Cientificas. Mem Inst Oswaldo Cruz, Vol 95, Suppl 1: 33-40.

77. Biswas S, Escalante AA, Chaiyaroj S, Angkasekwinai P, Lal AA (2000) Prevalence of point mutations in the dihydrofolate reductase and dihydropteroate synthetase genes of Plasmodium falciparum isolates from India and Thailand: a molecular epidemiologic study. Tropical Medicine and International Health, 5: 737-743.

78. Lehmann T, Blackston CR, Besansky N, Escalante AA, Collins FH, Hawley WA (2000) The effect of the Rift Valley on gene flow betweenAnopheles gambiae populations in Kenya: the mtDNA perspective. Journal ofHeredity, 91: 165-168.

79. AyalaFJ, Escalante AA, Rich SM (1999) Evolution of Plasmodiumand the recent origin of the world populations of Plasmodium falciparum. Parassitologia, 41: 55-68.

80. Lyman DF, Monteiro FA, Escalante AA, Cordon-Rosales C, Wesson DM, Dujardin J P, Beard CB (1999) Mitochondrial DNA Sequence Variation Among Triatomine Vectors of Chagas Disease. American Journal of Tropical Medicine and Hygiene, 60: 377-386.

81. Xiao LH, Morgan UM, Limor J, Escalante A, Arrowood M, Shulaw W, Thompson RCA, Faye R, Lal AA (1999) Genetic diversity within Cryptosporidium parvum and related Cryptosporidiumspecies. Applied Environmental Microbiology, 65: 3386-3391.

82. Xiao L, Escalante L, Yang C, Sulaiman I, Escalante AA, Montali RJ, Fayer R, Lal AA (1999) Phylogenetic Analysis of Cryptosporidium Parasites Based on the Small-Subunit rRNA Gene Locus. Applied Environmental Microbiology 1999 65:1578-1583.

83. Escalante AA, Freeland DE, Collins WE, Lal AA (1998) The evolution of primate malaria parasites based on the gene encoding cytochrome b from the linear mitochondrial genome. Proceedings of the National Academy of Sciences USA, 95: 8124-8129.

84. Escalante AA, Lal AA, Ayala FJ (1998) Genetic Polymorphism and Natural Selection in the Malaria Parasite Plasmodium falciparum. Genetics, 149:189-202.

85. Wolfe ND, Escalante AA, Karesh WB, Kilbourn A, Spielman A, Lal, AA (1998) Wild Primate Populations In Emerging Infectious Disease Research: The Missing Link? Emerging Infectious Diseases 4:149-158.

86. Escalante AA, Goldman IF, De Rijk P, De Wachter R, Collins WE, Qari SH, Lal AA (1997) Phylogenetic study of the genus Plasmodium based on the secondary structure-based alignment of the Small Subunit ribosomal RNA. Molecular Biochemestry and Parasitology, 90: 317-321.

87. Peng MM, Xiao L, Freeman AR, Arrowood MJ, Escalante AA, Weltman AC, Ong CSL, Mac Kenzie WR, Lal AA, Beard CB (1997) Genetic polymorphism among Cryptosporidium parvum isolates: evidence for two distinct human transmission cycles. Emerging Infectious Diseases, 3: 567-573.


88. Ayala FJ, Escalante AA (1996) The evolution of human populations: a molecular perspective. Molecular Phylogenetics and Evolution, 5: 188-201.

89. Escalante A, Ayala FJ (1995) Origin of Plasmodium and other Apicomplexa based on rRNA genes. Proceedings of the National Academy of Sciences USA, 92:5793-5797.

90. Escalante A, Barrio E, Ayala FJ (1995) Evolutionary origin of human and primate malarias: evidence from the circumsporozoite protein gene. Molecular Biology and Evolution, 12:616-626.

91. Escalante A, Ayala FJ (1994) Phylogeny of the malarial genus Plasmodium, derived from ribosomal gene sequences Proceedings of the National Academy of Sciences USA, 91:11373-11377.

92. Ayala FJ, Escalante A, O'hUigin C, Klein J (1994) Molecular genetics of speciation and human origins Proceedings of the National Academy of Sciences USA, 91: 6787-6794.

93. Linares OJ, Escalante A (1992) A new subspecies of the South American flat-headed bat Neoplatymops mattogrossensis from southern Venezuela. Mammalia, 56:417-424.

94. Espinoza MR, Pericchi LR , Carrasco GH, Escalante A, Martínez O, González R (1991) Prognostic indicators of chronic chagasic cardiopathy. International Journal of Cardiology, 30: 195-202.

95. Escalante A, Botto C (1990): Biometric characteristics of Onchocerca volvulus in two neotropical population. Annals of Tropical Medicine and Parasitology, 84: 633-635.

96. Escalante A (1990) Una comunidad de artrópodos asociada a la fermentación del cactus Pilosocereus lanuginosus. Ecotrópicos 3: 52.

97. Escalante A, Benado M (1990) Predation of the cactophilic fly, Drosophila starmeri in the columnar cactus Pilosocereus lanoginosus. Biotropica, 22: 48-50.

98. Delgado O, Botto C, Mattei R, Escalante A (1989) Effect of abendazol in experimental toxocariasis of mice. Annals of Tropical Medicine and Parasitology, 83: 621-624.

99. Botto C, Escalante A, Arango M, Yarzábal L (1988) Morphological differences among Venezuelan and African microfilariae of Onchocerca volvulus. J of Helmintology, 62: 345-351.

PEER-REVIEWED SYMPOSIUM, PROCEEDINGS, AND BOOK CHAPTERS:

100. Escalante AA, Ayala FJ (2012) Malaria: Host Range, Diversity and Speciation, In: Sibley D. (Ed) Evolution of Virulence of Eukaryotic Microbes, Wiley Blackwell. Pages 93-110.

101. Todd CW, Udhayakumar V, Escalante AA, Lal AA. (2007) Malaria Vaccines. In:Tibayrenc M (Ed)Encyclopedia of infectious diseases: Modern methodologies. John Wiley and Sons, Inc. Pages 137-150.

102. Moscarella R, Aguilera M, Escalante AA (2007). Genética de la Conservación del venado caramerudo de Venezuela e implicaciones para el manejo del venado de Margarita. Memoria de la Fundación La Salle de Ciencias Naturales. 67: 13-27.

103. Udhayakumar V, McCollum AM, Griffing S, Zhou Z, Barnwell J, Escalante AA (2006) Molecular markers for tracking the origin and spread of sulfadoxine and pyrimethamine resistant mutations. Proceedings of National Symposium, Oct. 19-20. pp: 9-15 Tribal Health. Regional Medical Research Centre for Tribals (ICMR). Jabalpur, India.

104. Cox-Singh J, Yau MSE, Irfanul HZ, Mohd TA, Lau TY, Escalante AA, Singh B (2005) Molecular Evolution of Malaria Parasites, Kota Samarahan, Sarawak, Universiti Malaysia Sarawak.

105. Merl D, Prado R, Escalante AA (2003) Bayesian Methods for Phylogeny Independent Detection of Positively Selected Amino Acid Sites, Proceedings of the American Statistical Association, Section on Bayesian Statistical Science, Biopharmaceutical Section, ENAR [CD-ROM], Alexandria, VA: American Statistical Association.


106. Escalante AA, Lal AA (2003) Evolutionary Biology of Malaria Parasites, in: Dronamraju KR (Ed) Infectious Disease: Host-Pathogen Evolution. Cambridge University Press.

107. Ayala FJ, Escalante AA, Lal A A, Rich SM (1998) Evolutionary Relationships of Human Malarias, in: Sherman, I W (Ed) Malaria: Parasite Biology, Pathogenesis, and Protection American Society for Microbiology Press Washington, DC, pp 285-300.

108. Escalante AA, Ayala, FJ (1996) Molecular Paleogenetics: The evolutionary history of Plasmodium and related Protists, in Evolutionary Paleogenetics: D Jablonski, D H Erwin, y JH Lipps (Eds) 21-41 pp The University of Chicago Press.

109. Ayala FJ, Escalante A, O'hUigin C, Klein J (1995) Molecular genetics of speciation and human origins, in: Ayala, FJ y Fitch, W (Eds) Tempo and Mode in Evolution, National Academy Press, Washington DC, USA.

110. Lentino M, Escalante A (1994) Sistemática de los periquitos (Aves: Psittaciformes): Consecuencias de los errores históricos y morfológicos, in: Morales, L G (Ed) Biología y Conservación de los Psitácidos Venezolanos pp 17-24, Caracas, Venezuela.

WRITING AND OTHER CREATIVE ACTIVITIES

TECHNICAL REPORTS:

- Merl D, Prado R, Escalante AA (2005) Bayesian Estimation of Differential Selection and Phylogenetic Effects Using Generalized Linear Models. AMS Technical Report, UCSC #ams2005-03. (available at http://www.ams.ucsc.edu/~raquel/review/tr_1.pdf)

- Merl D, Prado R, Escalante AA (2004) Comparison of Bayesian, Maximum Likelihood and Parsimony Methods for Detecting Positive Selection. (available at http://www.ams.ucsc.edu/~raquel/review/tr_3)

- Escalante AA, Cranfield M, Pacheco MA, Parson N, McCutchan T (2007) Evolutionary Ecology of Avian Malarial parasites in the African Penguin (Spheniscus demersus) for the Maryland Zoo.

PRESENTATIONS SELECTED INVITED PRESENTATIONS (2002-2012):

1. Evolutionary genetics of malarial parasites: the value of comparative approaches, ASTMH 61st Annual Meeting, Atlanta, GA, Nov 2012.

2. Phylomedicine of Malaria. Satellite symposium in Phylomedicine, March 2012, Society for Molecular Biology and Evolution, ASU, Tempe, Arizona.

3. Evolutionary Genomics of Malarial Parasites: implications in vaccine development and malaria control, 2nd Annual Southwest Regional Symposium on Global Health: Multidisciplinary approaches in Global Health. U of New Mexico, Albuquerque, October 18-19, 2010.

4. Evolutionary genomics of malarial parasites, 110th General Meeting of the American Society for Microbiology. San Diego, May 23-27, 2010.

5. Molecular Epidemiology of Plasmodium vivax: tools for Malaria Control, 14th ICID congress. Miami, March 9 to 11, 2010.


6. The evolution and distribution of primate of non-human primate malarias in South East Asia. Vivax malaria research III: 2009 and beyond. University of South Florida-Bill & Melinda Gates Foundation- NIH- Instituto Gorgas de Estudios de la Salud. Gamboa, Panama, May 2009.

7. The dynamic of mutations associated with antimalarial drug resistance in Plasmodium falciparum(with Y. Kim, ASU, and D. Smith, U. of Florida).Resources for the Future- Conference on Anti-Malarial Drug Treatments in Kruger National Park, South Africa, April 2008.

8. Synanthropic Primates and Disease Risk in Asia: Malaria and Simian Viruses (with Lisa Jones-Engel, Division of International Programs, U. of Washington-NPRC), ecoHEALTH Meeting, Global Institute of Sustainability, ASU, Tempe, May 2008.

9. What It Is and What It Does: Historical and Conceptual Perspectives on Parasite Classification. Systematics and Biodiversity: Concepts and Prospects, March 2008, International Institute for Species Exploration, ASU.

10. Impact of genetic diversity on malaria vaccine efficacy, insymposium Genetic diversity in Plasmodium falciparum: natural and vaccine-induced immunity the ASTMH 55th Annual Meeting, November 2006, Atlanta, Georgia.

11. Dynamic of antimalarial drug resistance in Plasmodium falciparum. National Consultation on Drug Resistance in Malaria, Tuberculosis and HIV/AIDS, September 2005, Mumbai, India.

12. Molecular Epidemiology. Latin American Molecular Epidemiology Workshop. University Sao Paolo, Brazil. July 4-8, 2005.

13. Molecular evolutionary studies in human malaria: building bridges between evolutionary biology and biomedical research. Second International Conference on Malaria, Johns Hopkins Malaria Research Institute Malaria Institute, August, 2004.

14. Challenges and opportunities for integrating molecular tools and population based approaches in monitoring anti-malarial drug resistance,ASTMH 53rd Annual Meeting, Miami, Florida, November 2004.

15. The genetic diversity of Plasmodium vivax and its relationship to monkey, Vivax Malaria Research: 2002 and Beyond. Multilateral Initiative on Malaria (MIM), February 2002, Bangkok, Thailand.

16. Population Genetic Studies in Human Malarial Parasites: from Drug Resistance to Vaccine Design. American Society for Microbiology, Southeastern Branch Annual Meeting, Noviembre 7–9, Gainesville, Florida, 2002.

17. Molecular evolution of Plasmodium. Evolution of Infectious Diseases, National Institutes of Health, Bethesda, Maryland, August 2002.

RECENT SUBMITTED PRESENTATIONS (2005-2012): (‡ = already published in a peer review journal, names underlined are undergraduate or graduate students):

1. Pacheco MA, Taylor J, Dantas-Machado RL, Rachid-Viana GM, Povoa MM, Herrera S, Bacon DL, Beg MA, Fairhurst RM, Escalante AA. The genetic diversity of Plasmodium vivax in populations from the Americas as inferred from mitochondrial genome sequences. ASTMH 61st Annual Meeting, Atlanta, GA, Nov 2012.

2. Pacheco MA, Muehlenbein MP, Fisher D, Escalante AA. Ascertaining the radiation of primate malarias in Asia: using comparative approaches to understand the evolution of merozoite proteins. ASTMH 61st Annual Meeting, Atlanta, GA, Nov 2012.

3. Pacheco MA, Jones-Engel L, Rice B, Acosta M, Crandfield M, Escalante AA. Limitations of single gene mitochondrial approaches for identifying species of malarial parasites. ASTMH 61st Annual Meeting, Atlanta, GA, Nov 2012.


4. Rice B, Acosta M, Pacheco MA, Carlton JM, Galinski MR, Escalante AA. A more ancient origin for high copy number of the merozoite surface protein 3 (MSP-3) family. ASTMH 61st Annual Meeting, Atlanta, GA, Nov 2012.

5. Chenet S, Blair S, Zuluaga Idárraga LM, Escalante AA. Longitudinal study of sulfadoxine-pyrimethamine (SP) resistance in turbo, Colombia. ASTMH 61st Annual Meeting, Atlanta, GA, Nov 2012.

6. Chenet S, Villegas L, Escalante AA. Understanding the local population structure of Plasmodium in the context of malaria control. ASTMH 61st Annual Meeting, Atlanta, GA, Nov 2012.‡

7. Chenet S, Zuluaga Idárraga LM, Blair S and Escalante AA. Genetic structure of Plasmodium falciparum: implications on malaria control and elimination. 2nd Nordic malaria conference. University of Copenhagen 2012.

8. Pacheco MA, Malukiewicz J, Elango AD, Escalante AA. Contrasting patterns of selection on the orthologous genes encoding Merozoite Surface Proteins 4 (MSP-4) and 5 (MSP-5) in Plasmodium spp. ASTMH 60th Annual Meeting, Philadelphia, PA, Dec 2011.

9. Pacheco MA, Reid MJ, Schilaci MA, Lowenberger CA, Galdikas BM, Jones-Engel L, Escalante AA. Origin of a linage of Plasmodium species in Orangutan. ASTMH 60th Annual Meeting, Philadelphia, PA, Dec 2011.‡

10. Acosta M, Rice B, Pacheco MA, Villegas L, Escalante AA. Similar diversity of the Merozoite Surface Protein 3 Alpha (MSP-3a) subfamily in Thai and Venezuelan Plasmodium vivax populations. ASTMH 60th Annual Meeting, Philadelphia, PA, Dec 2011.

11. Griffing SM, Viana GR, Mixson-Hayden T, Sridaran S, Alam MT, McCollum AM, de Oliveira AM, Barnwell JW, Escalante AA, Povoa MM, Udhayakumar V. The population structure of Amazonian Plasmodium falciparum. ASTMH 60th Annual Meeting, Philadelphia, PA, Dec 2011.

12. Pacheco MA, Battistuzzi FU, Lentino M, Cranfield M, Garcia-Amado MA, Escalante, AA. The radiation of Neoaves base on complete mitochondrial genomes. IX Congreso de Ornitologia Neotropical, Cusco-Peru, Nov, 2011. ‡

13. Pacheco MA, Elango AD, Rahman AA, Escalante AA. Genetic diversity of the merozoite surface proteins 8 (MSP-8) and 10 (MSP-10) in Plasmodium spp. ASTMH 59th Annual Meeting, Atlanta, GA, Nov 2010. ‡

14. Battistuzzi FU, Pacheco MA, Jones-Engel L, Cranfield M, Krief S, Snounou G, Gruner AC, Escalante AA. Investigating tempo and mode in the evolution of human malarial parasites. ASTMH 59th Annual Meeting, Atlanta, GA, Nov 2010.‡

15. Chenet SM, Pacheco MA, Escalante AA. Evidence for negative selection acting on the gene encoding the merozoite surface protein-9 (MSP-9) in Plasmodium spp. ASTMH 59th Annual Meeting, Atlanta, GA, Nov 2010.

16. Miao M, Yang, Huang Y, Escalante AA, Cui L. Mitochondrial genetic variation and evolutionary history in AsianPlasmodium vivax. ASTMH 59th Annual Meeting, Atlanta, GA, Nov 2010.‡

17. Demas A, Lucchi NW, Oberstaller J, DeBarry J, Srinivasamoorthy G, Sumari D, Kabanywanyi AM, Villegas L, Escalante AA, Kachur SP, Barnwell JW, Peterson DS, Kissinger JC, Udhayakumar V. Novel molecular diagnostic targets for the detection of Plasmodium falciparum and P. vivax. ASTMH 59th Annual Meeting, Atlanta, GA, Nov 2010.‡

18. Griffing SM, Mixson-Hayden T, Sridaran S, Alam MT, McCollum AM, Cabezas C, Marquiño W, Barnwell JW, Macedo De Oliveira A, Lucas C, Arrospide N, Escalante AA, Bacon D, Udhayakumar V. Peruvian Plasmodium falciparum: historical bottlenecks or recent introductions? ASTMH 59th Annual Meeting, Atlanta, GA, Nov 2010.‡


19. Pacheco MA, Junge RE, Battistuzzi F, Williams CV, Jones-Engel L, Escalante AA. Origin and Evolutionary Relationships of Malarial Parasites in Lemurs. ASM 110th General Meeting, San Diego, California, 2010.‡

20. Vinayak S, Alam Md T, Sem R, Shah NK, Susanti AI, Lim P, Muth S, Maguire JD, Rogers WO, Fandeur T, Barnwell JW, Escalante AA, Wongsrichanalai C, Ariey F, Meshnick SR, Udhayakumar V. Multiple Genetic Backgrounds of the Amplified Plasmodium falciparum Multidrug Resistance (pfmdr1) Gene and Selective Sweep of 184F Mutation in Cambodia. ASTMH 58th Annual Meeting, Washington, DC, 2009.‡

21. McCollum AM, Udhayakumar V, Escalante AA. Genetic hitchhiking, selective sweeps, and multiple origins of drug resistant Plasmodium falciparum in three distinct populations.ASTMH 57th Annual Meeting, New Orleans, Louisiana, 2008. ‡

22. McCollum AM, Tahar R, Basco LK, Udhayakumar V, Escalante AA. Hitchhiking and selective sweeps of Plasmodium falciparum sulfadoxine and pyrimethamine resistant alleles in Cameroon. ASTMH57th Annual Meeting, New Orleans, Louisiana, 2008.‡

23. Griffing S, Syphard L, Sridaran S, McCollum AM, Villegas L, Escalante AA, Venkatachalam U. Fixation of mutations and a single origin of pfcrt and pfmdr1 haplotypes in Plasmodium falciparum from Venezuela. ASTMH 57th Annual Meeting, New Orleans, Louisiana, 2008.‡

24. Syphard LM, Sridaran S, Griffing SM, Mixson T, McCollum AM, Villegas L, Escalante AA, Udhayakumar V. Molecular profile of drug resistant mutations associated with Pfcrt and Pfmdr-1 genes in Plasmodium falciparum isolates from a malaria endemic region of Venezuela. International Conference on Emerging Infectious Diseases, March 2008, Atlanta, Georgia.‡

25. Bacon DJ, Griffing S, McCollum AM, Salas C, Soberon V, Santolalla M, Haley R, Tsukayama P, Lucas C, Escalante AA, Udhayakumar V. In depth evaluation of the effects created by a change in the national malaria treatment policy over an eight year period on drug resistant genotypes in the Amazon basin region of Peru. Molecular Approaches to Malaria, Victoria, Australia, 2008. ‡

26. Escalante AA. The evolution and distribution of primate malarias in South East Asia. Comparative Genomics of Plasmodium. September 2007, American Museum of Natural History, New York City, New York.‡

27. Pacheco-Delgado MA, Ryan E, Escalante AA. Comparative study of the genetic diversity of the rhoptry -associated protein 1 (RAP-1) in Plasmodium spp. ASTMH, 56th Annual Meeting, November 2007, Philadelphia, Pennsylvania. ‡

28. Zhou Z., Griffing SM, de Oliveira AM, McCollum AM, Quezada WM, Arrospide N, Escalante AA, Udhayakumar V. Decline in sulphadoxine-pyrimethamine resistant dhfr and dhps alleles after changes in drug policy in the Amazon region of Peru. ASTMH 56th Annual Meeting, November 2007, Philadelphia, Pennsylvania.‡

29. Chenet SM, Bacon DJ, Escalante AA, Branch OH. Genetic diversity associated with vaccine candidate antigens in Plasmodium falciparum and P. vivax isolates from the Amazon region of Peru. ASTMH, 56th Annual Meeting, November 2007, Philadelphia, Pennsylvania.‡

30. McCollum AM, Griffing SM, Zhou Z, Terlouw DJ, Kariuki S, Lal AA, ter Kuile FO, Udhayakumar V, Escalante AA. Independent evolution of mutant dhfr and dhps alleles in an area of high transmission in western Kenya. ASTMH, 56th Annual Meeting,November 2007, Philadelphia, Pennsylvania.

31. Jones-Engel L, Engel GA, Schillaci M, Pacheco Delgado MA, Escalante AA. Non-human primate Malarias: are monkeys reservoirs of malarial zoonotic infection? 30th Meeting of the American Society of Primatologists (June 2007).‡

32. McCollum AM, Mueller K, Villegas L, Udhayakumar V, Escalante AA.Fixation of P. falciparum SP resistant mutations in an area with low genetic diversity. ASTMH 55th Annual Meeting, November 12-16, 2006. Atlanta, Georgia‡.


33. Hamel MJ, Poe A, Bloland P, McCollum AM, Zhou Z, Shi YP, Ouma P, Otieno K, Vulule J, Escalante AA, Udhayakumar V, Slutsker L. Does daily cotrimoxazole promote the selection of Plasmodium faliciparum dyhydrofolate reductase (DHFR) and dyhydropteroate synthase (DHPS) mutations? ASTMH 55th Annual Meeting, November 12-16, 2006. Atlanta, Georgia‡.

34. Merl D, Prado R, Escalante A. Bayesian random effects models for investigating variability in codon substitution rates. ISBA Eighth World Meeting on Bayesian Statistics, June 2006, Valencia, Spain‡.

35. Pacheco MA, Poe AC, Collins WE, Lal AA, Tanabe K, Kariuki SK, Udhayakumar V, Escalante AA. Comparative Study of the genetic diversity of the 42 Kda fragment of the merozoite surface protein-1 in Plasmodium falciparum and P. vivax. Society for Molecular Biology and Evolution Annual Meeting, May 2006, Tempe, Arizona‡.

36. McCollum AM, Mueller K, Udhayakumar V, Escalante AA. Multiple origins of drug resistant malaria. Society for Molecular Biology and Evolution Annual Meeting, May 2006,Tempe, Arizona‡.

37. Mueller K, McCollum AM, Villegas L, Udhayakumar V, Escalante AA. Molecular Analysis of Sulfadoxine-Pyrimethamine Resistant Genotypes in Plasmodium falciparum Isolates from Venezuela. International Conference on Emerging Infectious Diseases, March 2006, Atlanta, Georgia ‡.

38. Hamel MJ, Bloland PB, Escalante AA, Greene C, Chiller T, Shi YP, Ouma P, Otieno K, Poe A, Zhou A, Goldman I, Vulule J, Williamson J, Udhayakumar V, Slutsker L. Does daily cotrimoxazole promote the selection of Plasmodium falciparum dyhydrofolate reductase (dhfr) and dyhydropteroate synthase (dhps) mutations? Annual Meeting, American Society of Tropical Medicine and Hygiene, December 2005, Washington, D.C.‡

39. McCollum AM, Poe AC, Hamel MJ, Huber C, Zhou Z, Shi YP, Ouma P, Vulule J, Bloland PB, Slutsker L, Barnwell J, Udhayakumar V, Escalante AA. Identification of novel microsatellite haplotypes for the triple mutant dhfr allele and identification of highly resistant Plasmodium falciparum in an area of intense transmission in Africa. Annual Meeting, American Society of Tropical Medicine and Hygiene, December 2005, Washington, D.C.‡

TEACHING EXPERIENCE COURSES TAUGHT AT ASU:

- Organic Evolution, 3 credits (226 students Spring 2012 with K Pigg), including curriculum revision and innovative TAs proposal,

- General Microbiology for life sciences majors, 3 credits (110 students Fall 2005, 141 student Fall 2006, 150 students Fall 2007, 217 students Fall 2008, 200 students Fall 2009, 185 students Fall 2010 with V. Stout; 143 students Spring 2013 with D. Lake).

- Ecology and Evolution of Emerging Infectious Diseases, 3 credits (25 students Spring 2007, 15 students Spring 2008, 26 students Spring 2009, 36 students Spring 2011, 34 students Fall 2012).

- Evolutionary Biology of Parasites and Pathogens, Graduate Seminar, 2 credits (10 students, Spring 2010).

COURSES TAUGHT ELSEWHERE:

- Instructor: Molecular Ecology and Evolution, graduate program in Ecology, IVIC, 10-15 students each section, springs 1999, 2001, and 2003.

- Instructor: Molecular Evolution at the Program in Population Biology, Ecology, and Evolution program, Emory University (1997), 8 students.


- Instructor: Population genetics at the Centers for Disease Control and Prevention (1997), 40 students, 30 hours.

- Lecturer: Molecular Evolution Course. Population Biology and Evolutionary Ecology program. Department of Biology. Emory University (Jan/98-Apr/98).

- Advisor: Students Morehouse College Cooperative Summer Program at CDC (1996-1998).

- Instructor: Introduction to population genetics (12 hours), Ecology Center, IVIC (August 1996).

- Teaching Assistant: “Biodiversity of Life” and “Quantitative Ecology” at UCI (1990-93).

- Instructor: Computer labs directed to minority students organized by the Hughes High School Biotechnology & Research Program and California Alliance for Minority Participation in Science (CAMP) program, UC Irvine (1990-93).

- Teaching Assistant: "Evolutionary and Population Biology" course, USB (Jan/88- Mar/88).

- Undergraduate Teaching Assistant: Plant Physiology (Sep/81-Dec/81) and Biochemistry (Sep/82 - Dec/82 and Sep/83 - Dec/83), USB.

GRADUATE PROGRAMS (PARTICIPATION AS FACULTY):

- PhD programs in Biology and Microbiology at the School of Life Sciences.

- Multi School programs: Applied Mathematics for the Life and Social Sciences, Evolutionary Biology, Molecular and Cell Biology, Environmental Life Sciences, and PhD in Global Health.

PAST PARTICIPATION IN GRADUATE PROGRAMS (AS FACULTY):

- PhD Microbiology, “Instituto Venezolano de Investigaciones Científicas” (IVIC), Venezuela. Apr 98- Dec 2004.

- PhD Microbiology, “Facultad de Farmacia y Bioanálisis”, “Universidad de Los Andes” (ULA), Venezuela. Sep 98- Dec 2004.

- PhD Biomedical Sciences (“Ciencias Médicas Fundamentales”), School of Medicine, ULA, Sep 99- Dec 2004.

- Graduate program in Population Biology and Evolutionary Ecology, Department of Biology, Emory University, Atlanta, Georgia, 2002-2010.

INTERNATIONAL WORKSHOPS (2000-2012):

- Organizer: Primate Malaria genomics: from populations to comparative studies, co-organized with Professor Jane Carlton, NYU. ASTMH 61st Annual Meeting, Atlanta, GA, Nov 2012.

- Organizer: Satellite symposium in Phylomedicine, March 2012, co-organized with Professor Sudhir Kumar. Supported by the Society for Molecular Biology and Evolution.

- Organizer: Workshops in basic bioinformatics tools, CeCALCULA-ULA, Venezuela (13 national workshops from 2000 to 2011, more than 120 trainees), supported by University of Los Andes and FONACIT-Venezuela.

- Instructor and Organizer: Host-Parasite Interactions and Vector Biology: A Basic Course. Sponsored by IVIC and American Society for Microbiology (2007), Caracas, Venezuela (15 students from 7 Latin-American countries).


- Instructor and Organizer: Introduction to Molecular Epidemiology, Sao Paulo, Brazil (July 2005) (20 Students from 8Latin-American countries), supported by UNU-BIOLAC, Centers for Disease Control and Prevention, and University of Sao Paolo.

- Instructor and Organizer: Introduction to Molecular Epidemiology, Mérida, Venezuela (Jul 2004) (Students from 8 Latin-Americancountries), supported by United Nations University (UNU)-Biotechnology for Latin America and the Caribbean (BIOLAC), Centers for Disease Control and Prevention, Pan-American Health Organization, and University of Los Andes-Venezuela.

- Instructor: Phylogenetic Methods. Instituto de Estudios Avanzados, organizad by UNU-BIOLAC, UNESCO and the Instituto de Estudios Avanzados. May 2004, Caracas, Venezuela.

- Instructor and Organizer: 1st and 2nd Workshop “New Frontiers of Bioinformatics in Latin America” CeCALCULA-ULA, Venezuela, (Nov 2003 and Nov 2004) (30 Students each from 8 countries, supported bio UNU-BIOLAC and University of Los Andes, Venezuela).

- Instructor: Population Genetics in Public Health, Universiti Malaysia Sarawak (UNIMAS), Malaysia, July 2003 (30 students).

- Organizer: International workshop "Biociencias y Medicina Molecular para América Latina y el Caribe". May 2001, Centro Latinoamericano de Ciencias Biológicas-CLAB, IVIC-UNESCO.

ACADEMIC TRAINING/MENTORING POST-DOCTORAL FELLOWS:

- Fabia U. BATTISTUZZI, Biodesign Institute, ASU (2009-2012).

- Kristan SCHNEIDER, The Biodesign Institute, ASU (2010-2011).

- Shannon TAKALA, U. of Maryland (Internship Spring 2007).

- Naomi W. LUCCHI, ASM fellow at the Malaria Branch, CDC, as part of my collaboration with CDC: Estimating the burden and impact of malaria in pregnancy in Latin America (2007- 2009).

- Alicia WILBUR, SHESC, ASU, as part of my collaboration with the project People, Primates, and Pathogens supported by the program “Late Lessons from Early History” (2007-2009).

GRADUATE STUDENTS:

- Lina M. ZULUAGA, Universidad de Antioquia, Colombia, PhD in Epidemiology (committee member, 2012- ).

- Andreina CASTILLO SIRI, ASU, PhD program in Evolutionary Biology (Advisor 2010- ).

- Stella CHENET, ASU, PhD program in Microbiology (Thesis Director, 2008-).

- Penny LANGHAMMER, ASU, PhD Biology (committee member, Biology, 2008 - ).

- Crystal HEPP, ASU, PhD program in Molecular & Cellular Bio (committee member, 2008-2013).

- Benjamin Rice, ASU,Postbaccalureate Research Education Program (PREP), Biomedical Research, (2012-2013).

- Oliver HYMAN, ASU, PhD Biology (committee member, Biology, 2008 -2012).

- Lina M. ZULUAGA, Universidad de Antioquia, Colombia, PhD Epidemiology (Training, Jan-Feb 2012).

- Saheli DATTA, UC Santa Cruz, PhD program, Department of Applied Mathematics and Statistics (committee member, 2008-2011).

- Elena ARTIMOVICH, Molecular Epidemiology PhD Program, University of Maryland (Training Oct 2011).


- Aditi VADODKAR, ASU, MSc Computational Biosciences (Advisor, 2010-2011)

- Monica ACOSTA, ASU,Postbaccalureate Research Education Program (PREP), Biomedical Research, (2011-2012).

- Renxia HUANG, ASU, PhD program in Molecular & Cellular Bio (committee member, 2010 -2011).

- Haralambos FOKIDIS, ASU,PhD Biology (committee member, 2007 - 2010).

- Garima KUSHWAHA, ASU, MSc Computational Biosciences (committee member, 2008-2009).

- Sean GRIFFING, Emory University, PhD PBEE (Emory University, co-advisor, 2004-2010), currently ASM postdoctoral fellow at CDC.

- Andrea MCCOLLUM, Emory University (PhD PBEE, Thesis Director, 2002-2007), currently at CDC.

- Daniel MERL, PhD, UC Santa Cruz (Co-advisor, PhD, Department Applied Mathematics and Statistics, 2005-2007), currently postdoctoral fellow, Department of Statistical Science at Duke.

- Shannon TAKALA, U of Maryland (PhD molecular epidemiology, committee member, 2005 – 2006), currently assistant professor at U. of Maryland.

- Trina PERRONE, Universidad Simón Bolívar (USB), Venezuela, (PhD in Biology, Co-advisor, 2000-2006), currently researcher at the Instituto Venezolano de Investigaciones Científicas (IVIC).

- Ricardo CHAURIO, Universidad Simón Bolívar(USB), Venezuela, (MSc in Ecology, Advisor, 2006), currently PhD student at Friedrich-Alexander-University Erlangen-Nuremberg, Germany.

- Omar CORNEJO, Instituto Venezolano de Investigaciones Científicas (IVIC), Venezuela (MSc in Ecology, Advisor, 2003-2005), currently postdoctoral fellow at Stanford.

- Rosa MOSCARELLA, USB, Venezuela (MSc in Ecology, advisor, 2002-2004), currently PhD student at Michigan State University.

- Ana P. GONCALVEZ, IVIC, Venezuela, (PhD Microbiology, committee member 2002-2003) (currently at the Molecular Viral Biology Section, NIA/NIH).

UNDERGRADUATE STUDENTS WITH FORMAL RESEARCH PROJECTS (2-3 SEMESTERS):

ARIZONA STATE UNIVERSITY (TOTAL: 13):

Jaye F. ESPINAS (2013-), Maria LINDSETH (Summer 2012-2013), Wenyu ZHENG, (Undergraduate Honors Thesis Committee Member, Mathematics, 2011-2012); Benjamin RICE, ASU SOLUR program(Mentor Undergraduate Honors Thesis, CLAS Dean's Undergraduate Research Scholarship in the Life Sciences, 2009-2012); Monica ACOSTA (Mentor Undergraduate Honors Thesis, 2009-2011, Currently Graduate Student in PSU); Alamelu ELANGO(Advisor, 2008-2009) and Post-Bachelorette position (2009) (currently graduate student); Basant VIRDEE(Undergraduate Honors Thesis Committee Member) (2009-2010); Samantha VARNER(Undergraduate Honors Thesis Committee Member) (2008-2009); Abir RAHMAN, ASU-SOLUR program (Advisor, Fall 2006- Spring 2008, Currently MSc in Georgia Tech) (currently graduate student); Stephen COX(Advisor Fall 2007- Spring 2008) (currently Medical School, U of Arizona); Shannon CURRY(Undergraduate Honors Thesis Committee Member) (Spring 2008); Elizabeth RYAN(Mentor Undergraduate Honors Thesis, 2006) (currently working in the private sector); Rachel SMITH(Undergraduate Honors Thesis Committee Member) (2005).

EMORY UNIVERSITY (TOTAL: 2):

Jessica L. KATZ, Emory University, Summer Undergraduate Research Program at Emory (SURE) Program (Advisor, 1998); Monica LICHT, Emory University, SURE Program (Advisor, 1996).

VENEZUELA (TOTAL: 5):


Ester DURREGO, Universidad Simón Bolívar(Advisor, 2004) (currently PhD student at Universidad Simón Bolivar, Venezuela); Fabiola LEÓN, Universidad de Los Andes (ULA) (Mentor Undergraduate Thesis, 2004) (currently PhD student at Universidad Central de Venezuela, UCV); Ascanio ROJAS, ULA, Venezuela (Mentor Undergraduate Thesis, 2003) (currently Research Assistant at ULA, Venezuela); Omar CORNEJO, USB, Venezuela (Mentor Undergraduate Thesis, 2003); Harold P de VLADAR, UCV, Venezuela (Advisor, 2003) (currently Postdoctoral fellow, University of Groningen, The Netherlands)

UNDERGRADUATE STUDENTS: LABORATORY INTERNSHIPS AND/OR UNDERGRADUATE RESEARCH PAPERS: ARIZONA STATE UNIVERSITY (TOTAL: 19):

Corey BENEDUM (Spring 2012); Kaitlyn VERBANIC (Spring 2012); Thanh NGUYEN (Summer 2011); Katelyn CONANT (Spring 2011): Saaiqa Zulfikar MAREDIA (Fall 2010); Patrick VARVEL (Summer 2010); Shrishti NAND (Spring 2010); Laura KOSIROG (Spring 2009); Jared NOBLE (Spring 2009); Amanda HUSAYNO(Spring 2008); Lev KOROVIN(Spring 2008); Aaron NAHM(Spring 2008); Amelia RANA(Spring 2008); Kisha SIMMONS(Spring 2008); Malaya FLETCHER(Spring-Fall 2007); Alexandra HARRETT(Fall 2007); Kathryn FITZPATRICK(Spring 2007); Jessica ANDERSON(Spring 2006); Angel MORROW, MARC program (Spring 2006); Lisa NAYEBPOUR(Fall 2005).

SERVICE AND PROFESSIONAL ACTIVITIES NATIONAL AND INTERNATIONAL:

- Founder President CoEvolution Society.

- Member of the Plasmodium Comparative Genomics Group (2007- Present): two white papers requesting funding for sequencing genomes of Plasmodium vivax isolates and related non-human primate malarial parasites. Status: awarded.

- Member of Scientific Consulting Group, Malaria Host-Pathogen Interaction Center (http://mahpic.emory.edu), NIAID-NIH (2012-2017).

- Member (2011- Present): Research network for vector transmitted diseases control and prevention (Red de Investigación Multidisciplinaria para la Prevención y Control de Enfermedades Transmitidas por Vectores), Colombia, awarded by COLCIENCIAS. I am a collaborator, this grant is linked to the project NIH 1U19AI089702“INTERNATIONAL CENTER OF EXCELLENCE FOR MALARIA RESEARCH: LATIN AMERICAN CENTER FOR MALARIA RESEARCH AND CONTROL”.

- University Malaya High Impact Research (HIR) Grant (2011-2013), Collaborator, PI: Indra Vythilingam (awarded), University Malaya, Malaysia. I am a collaborator. Dynamic of malarial parasites in humans and non-human primates.

- Invited Member of the Genetic Variation and Evolution Study Section, Center for Scientific Review, National Institutes of Health (Spring 2013).

- Editorial Boards: Infection, Genetics and Evolution/ Elsevier (2006-2009), Malaria Research and Treatment (2010- Present).

- Guest Editor: PLoS Genetics (1 manuscript, 2012), Evolutionary Applications (special section in Phylomedicine 2012-2013), PNAS (1 manuscript, 2013).

- Reviewer (last three years, 2009-2013): Acta Tropica, American Journal of Tropical Medicine and Hygiene, Antimicrobial Agents Chemotherapy, Emerging Infectious Diseases, Infection, Genetics and Evolution, The Malaria Journal, Molecular Biology and Evolution, Molecular Phylogenetics and Evolution, PLoS One, PLoS Genetics, PLoS Pathogens, Proceedings of the National Academy of Sciences USA, Science, Trends in Parasitology, and Vaccine.


- Member of the CDC malaria molecular epidemiology network supporting programs such as (i) RAVREDA/AMI, a network of investigators that are studying the epidemiology of malaria drug resistance in the countries from the Amazon Basin, (ii) SP resistance working group, and (iii) the impact of P. vivax in malaria in pregnancy in Latin-America (2005- 2012).

- Asian Pacific Malaria Elimination Network Grant (2010-2012), PI: P Udagama-Randeniya (awarded), University of Colombo, Sri Lanka. I am a collaborator. Dynamics of Plasmodium vivax parasite populations during malaria elimination efforts in Sri Lanka, with low transmission and unstable malaria.

- External Scientific Committee, Center for Applied Tropical Ecology and Conservation(CATEC),University of Puerto Rico (2007- 2009).

- Member of the e-workspace: community of practice on Malaria immunology biomarkers, UNICEF-UNDP-World Bank-WHO Special Program for Research and Training in Tropical Diseases (TDR) (2008-2009).

- Member Molecular Markers Steering Committee for Artemisinin resistance. This coordinates the molecular markers core of a grant from the Bill and Melinda Gates Foundation entitled: Artemisinin resistance: pilot studies to confirm, characterize and plan for containment (2008).

- Malaria Special Emphasis Panel, Centers for Disease Control and Prevention. Revision of extramural grant proposals (Spring 2008).

- Consultant: Scientific Advisory Committee meeting, Malaria Reference Reagent Resource Center (MR4), April 2001.

PROFESSIONAL SOCIETIES/AFFILIATIONS:

- The CoEvolution Society

- The American Society of Tropical Medicine & Hygiene.

- The Society for Molecular Biology and Evolution. SCHOOL AND UNIVERSITY COMMITTEES:

- Associate Director for Adaptive Evolution, CEMI (May 2012-Present).

- Member, Personnel Committee, the Biodesign Institute, ASU (Jan 2012-Present).

- Member, Personnel Committee, Genomics, Evolution, and Bioinformatics, ASU (Jan 2010-Present).

- Interim Chair, Safety Committee, School of Life Sciences, ASU (Fall 2012).

- Member, Research and Collaboration Advancement Team, the Biodesign Institute, ASU (Aug 2011).

- Chair, Microbiology Graduate Program Committee, ASU (2007-2011); chair since January 2010.

- Member ASU Environmental Health & Safety Policy Committee (August 2010-Dec 2011).

- Chair, Member of the Safety Committee, School of Life Sciences, ASU (2008-2011).

- Member of the working group, Environmental Life Sciences (ELS) graduate program, ASU (2007-2009).

- SOLS Strategic Planning Committee, ASU (November 2008-May 2009).

- Member of the Safety Committee, School of Life Sciences, ASU (2006-2008).

- Member of the Arizona State University Center for Global Health Advisory Group (Nov 2005).

- SOLS-ASU, Search committees of Bacterial Pathogenesis, Member (July 2005 - August 2005); Immunology and Virology (two positions) from December 2009- 2010.


- Judge: Annual MGE@MSA Student Research Conference (5thApril 2005, 10thJanuary 2010).

- Coordinator, Graduate Program in Ecology, IVIC, Caracas, Venezuela (Sep 98-Apr 02).

- Committees at IVIC (Venezuela): Biotechnology (7/01-11/01), Public Relations (8/00- 8/01), IT services (5/98-10/99).

COMMUNITY OUTREACH

- Collaboration with the Maryland Zoo: assessing disease risk (malaria) in South African penguins and African Apes.Contact person: Mike Cranfield MD DVM, Conservation Program, E-mail: [email protected].

- Collaboration with the Columbus Zoo and Aquarium: assessing disease risk (malaria) in Lemurs. Contact person:Randall E. Junge DVM,E-mail:[email protected]

- Collaboration with the Humane Society: Disease risk in rescue animals (Avian malaria). Contact person: Roberto Aguilar DVM, E-mail: [email protected]

- Collaboration with the Fish and Wildlife Service and The Phoenix Zoo: assessing disease risk (avian malaria) in the Masked Bobwhite Quail. May 2008-August 2011. Contact person: Roberto Aguilar DVM, E-mail: [email protected]

OTHERS

- Bilingual (Spanish-English).

- Scientific Ethics/Human Subjects Training at the Centers for Disease Control and Prevention, Certification Number 4344. CITI Collaborative Institutional Training Initiative-Human Research Curriculum Completion Report, Ref # 6265321 (Completed June 2011).

- Instructor: Computer Lab, Universidad Central de Venezuela, UCV (Celular Biology Graduate Program 1993; and Universidad Simón Bolívar, USB (Sociedad Venezolana de Parasitología 1988).

- Computer and Statistical Consultantfor the Venezuelan Association of Cement Producers (A.V.P.C.). (Part-time position, Apr/88-Sep/89).

- ad honorem member of the Biology of Parasites Laboratory at the Institute of Tropical Medicine, UCV ( Mar/85-Sep/89 ).

- Research Assistant in Computing and Statistics to the Educational Research Center (C.I.E.), USB (Sep/85-Jan/89).

- Undergraduate Research Assistant in Computing and Statistics in the Department of Cell Biology, USB (Apr/83 -Dec/83) and Statistical Section of the Mathematics Department, USB(Jan/85 -Jul/85 &Apr/87-Jul/87) USB.

Documents

ANANIAS A. ESCALANTE Professor, School of Life … · ANANIAS A. ESCALANTE Professor, School of Life Sciences Arizona State University CENTER FOR EVOLUTIONARY MEDICINE AND INFORMATICS,