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Anatomy and Physiology Anatomy and Physiology 2211K2211K
Lecture FiveLecture Five
Slide 2 – Urinary system
Slide 3 – Urinary system’s function – filtering the blood
Slide 3 – Urinary system’s function – regulation of blood volume
Slide 3 – Urinary system’s function – regulation of ions
Slide 6 – Urinary system’s function – pH regulation
Slide 7 – Urinary system’s regulation - hormonal
Slide 8 – Urinary system’s regulation – Vitamin D
Slide 9 - Kidneys
Slide 10 - Nephron
Slide 11 – Histology of the nephron (glomerulus)
Slide 12 – Histology of the nephron (Bowman’s capsule)
Slide 13 – Histology of the nephron (Proximal convoluted tubule)
Slide 14 – Histology of the nephron (distal convoluted tubule)
Slide 15 – Histology of the nephron – juxtaglomerular apparatus
Slide 16 – Blood flow of the nephron and the kidneys
Slide 17 – Ureter and the urinary bladder
Slide 11 – urine formation
Slide 19 – Urea cycle
Slide 20 – Uric acid production
Slide 21 – Renal filtration
Slide 22 – Renal fraction
Renal plasma flow rateRenal plasma flow rate - the actual flow of plasma reaching - the actual flow of plasma reaching the kidneys is equal to the renal blood flow rate multiplied by the the kidneys is equal to the renal blood flow rate multiplied by the portion of the blood that is made up of plasma – which is portion of the blood that is made up of plasma – which is approximately 55%approximately 55%
1176mL/min x 0.55 = 646 mL plasma /min1176mL/min x 0.55 = 646 mL plasma /min
Filtration fractionFiltration fraction – the actual part of the plasma that is being – the actual part of the plasma that is being filtered through the glomerulus and the renal capsule. Filtration filtered through the glomerulus and the renal capsule. Filtration fraction averages 19% of the plasma flowing through the fraction averages 19% of the plasma flowing through the kidneyskidneys
646 mL plasma/min x 0.19 = 123.5 mL plasma per minute646 mL plasma/min x 0.19 = 123.5 mL plasma per minute
Slide 23 – Urine formation - glomerulus
Slide 23 – Filtration pressure
Slide 23 – reabsorption – proximal convoluted tubule
Slide 25 – Reabsorption – loop of Henle
Slide 26 – Ascending loop of Henle
Slide 26 – reabsorption – distal convoluted tubule
Slide 28 – Urine concentration