Upload
hoangthuy
View
213
Download
0
Embed Size (px)
Citation preview
ANATOMY AND PHYSIOLOGY FOR ICD-10
THE ENDOCRINE SYSTEM
Objectives
On completion of this chapter, you will be able to:
• Describe the primary glands of the endocrine system.
• State the primary functions of the endocrine glands.
• Describe the secondary glands of the endocrine system.
• State the vital function of the endocrine system.
• Identify and state the functions of the various
hormones secreted by the endocrine glands.
• Analyze, build, spell, and pronounce medical words.
• Describe each of the conditions presented in the
Pathology Spotlights.
• Complete the Pathology Checkpoint.
• Review Drug Highlights presented in this chapter.
• Provide the description of diagnostic and laboratory
tests related to the endocrine system.
• Identify and define selected abbreviations.
• Successfully complete the study and review section.
ANATOMY AND PHYSIOLOGY FOR ICD-10
THE ENDOCRINE SYSTEM
Lecture Outline
I. Anatomy and Physiology Overview -The endocrine system
is made up of glands and the hormones they secrete. The primary
glands of the endocrine system are the pituitary, pineal,
thyroid, parathyroid, islets of langerhans, adrenals, ovaries in
females, and testes in males. Some other organs such as the
brain, heart, lungs, liver, skin, thymus, placenta during
pregnancy, and the gastrointestinal mucosa also produce and
release hormones (Table 11-1, p. 353). The function of the
endocrine system involves the production and regulation of
chemical substances called hormones. A hormone is a chemical
transmitter that is released in small amounts and transported
via the bloodstream to a target organ or other cells. The
endocrine and nervous system work closely together to help
maintain homeostasis. The hypothalamus, a collection of
specialized cells that are located in the lower central part of
the brain, is the primary link between the endocrine and nervous
system. Nerve cells in the hypothalamus control the pituitary
gland by producing chemicals that either stimulate or suppress
hormone secretions from the pituitary.
ANATOMY AND PHYSIOLOGY FOR ICD-10
THE ENDOCRINE SYSTEM
A. The Pituitary Gland (Hypophysis) – a small gray gland
located at the base of the brain. The pituitary gland is known
as the master gland of the body because of its regulatory effect
on the other endocrine glands. It resides in a shallow
depression in the sphenoid bone called the sella turcica. It is
divided into an anterior and posterior lobe. (Fig. 11-1, p. 355)
1. The Anterior Lobe – or adenohypophysis secretes
several hormones that are essential for the growth and
development of bone, muscles, other organs, sex glands, the
thyroid gland, and the adrenal cortex. (Fig 11-2, p. 356)
a. Growth Hormone (GH) – also called somatotropin hormone
(STH), is essential for growth and development of bone, muscles,
and other organs. It also enhances protein synthesis, decreases
the use of glucose, and promotes fat destruction (lipolysis).
i. Hyposecretion may result in dwarfism and Simmonds’
disease.
ii. Hypersecretion may result in gigantism (early life)
and acromegaly (adults).
b. Adrenocorticotropin Hormone (ACTH) – essential for
growth and development of the middle and inner zones of the
ANATOMY AND PHYSIOLOGY FOR ICD-10
THE ENDOCRINE SYSTEM
adrenal cortex, which secretes the glucocorticoids cortisol and
corticosterone.
c. Thyroid-Stimulating Hormone (TSH) – essential for
growth and development of the thyroid gland. Stimulates
production of thyroxine and triiodothyronine and influences the
body’s metabolic processes.
d. Follicle-Stimulating Hormone (FSH) – gonadotropic
hormone that is essential in stimulating the growth of ovarian
follicles in females and sperm production in males.
e. Luteinizing Hormone (LH) – gonadotropic hormone
essential in the maturation process of the ovarian follicles and
stimulation of the corpus luteum in females and testosterone
production in males.
f. Prolactin (PRL) – known as lactogenic hormone (LTH).
Gonadotropic hormone that stimulates milk production after
childbirth.
g. Melanocyte-Stimulating Hormone (MSH) – regulates skin
pigmentation and promotes the deposit of melanin in the skin
after exposure to sunlight.
2. The Posterior Lobe – or neurohypophysis; secretes two
known hormones:
ANATOMY AND PHYSIOLOGY FOR ICD-10
THE ENDOCRINE SYSTEM
a. Antidiuretic Hormone (ADH) – also known as vasopressin
(VP). Stimulates the reabsorption of water by the renal tubules
and has a pressor effect that elevates blood pressure.
i. Oversecretion results in diabetes insipidus.
b. Oxytocin – acts on the mammary glands to stimulate the
release of milk and the stimulation of uterine contractions
during labor, delivery, and parturition.
B. The Pineal Gland (Body) – small, pine cone-shaped
gland located near the posterior end of the corpus callosum. It
secretes the following:
1. Melatonin – a hormone that may be released at night to
regulate the release of gonadotropin.
2. Serotonin – hormone that is a neurotransmitter,
vasoconstrictor, and smooth muscle stimulant and acts to inhibit
gastric secretions.
C. The Thyroid Gland – large bilobed gland located in the
neck. It plays a vital role in metabolism and regulates the
body’s metabolic processes. It secretes: (Fig. 11-3, p. 357)
1. Thyroxine (T4) – essential for maintenance and
regulation of the basal metabolic rate (BMR). It contains four
iodine atoms. Thyroxine influences growth and development and
ANATOMY AND PHYSIOLOGY FOR ICD-10
THE ENDOCRINE SYSTEM
the metabolism of fats, proteins, carbohydrates, water,
vitamins, and minerals.
2. Triiodothyronine (T3) – effective thyroid hormone that
contains three iodine atoms. It influences the basal metabolic
rate.
a. Hyposecretion of T4 and T3
i. Cretinism (infancy) and myxedema (adulthood)
ii. Hashimoto’s disease – chronic thyroid disease
b. Hypersecretion of T4 and T3
i. Hyperthyroidism or thyrotoxicosis
ii. Graves’ Disease, exophthalmic goiter, toxic goiter, or
Basedow’s disease
3. Calcitonin – also known as thyrocalcitonin. Calcitonin
is a thyroid hormone that influences bone and calcium metabolism
and maintains plasma calcium homeostasis.
D. The Parathyroid Glands – small, yellowish-brown bodies
occurring as two pairs. (Fig. 11-4, p. 358) The hormone secreted is
the:
1. Parathormone (PTH) – essential for the maintenance of
a normal serum calcium level. It aids in the metabolism of
phosphorus.
ANATOMY AND PHYSIOLOGY FOR ICD-10
THE ENDOCRINE SYSTEM
a. Hyposecretion of PTH – results in hypoparathyroidism,
which may result in tetany (Fig 11-5, p. 359).
b. Hypersecretion of PTH – results in hyperparathy-
roidism, which may result in osteoporosis, kidney stones, and
hypercalcemia.
E. The Pancreas (The Islets of Langerhans) – the islets
are small clusters of cells located within the pancreas. There
are three types of cells:
1. Alpha Cells – secrete glucagon, which aids in the
breakdown of glycogen to glucose. This results in an increase in
blood sugar.
2. Beta Cells – secrete insulin, which is essential for
the maintenance of normal blood sugar. Insulin promotes the use
of glucose in cells, thereby lowering the blood glucose level,
and plays a vital role in carbohydrate, protein, and fat
metabolism.
a. Hyposecretion – results in diabetes mellitus
b. Hypersecretion – results in hyperinsulinism
3. Delta Cells – secrete somatostatin, which suppresses
the release of glucagon and insulin. (Figs. 11-6 & 11-7, pp. 359
& 360)
ANATOMY AND PHYSIOLOGY FOR ICD-10
THE ENDOCRINE SYSTEM
F. The Adrenal Glands (Suprarenals) – two small,
triangular-shaped glands on top of each kidney. They consist of:
1. The Adrenal Cortex – secretes the following:
glucocorticoids, mineralocorticoids, and the androgens. (Fig 11-
8, p. 361)
a. The Glucocorticoids
i. Cortisol – a hydrocortisone that is the principle
steroid hormone secreted by the cortex. Hyposecretion results in
Addison’s disease and hypersecretion results in Cushing’s
disease.
ii. Corticosterone – a steroid hormone secreted by the
adrenal cortex. Is essential for normal use of carbohydrates,
absorption of glucose, a process known as gluconeogenesis, and
influences potassium and sodium metabolism.
b. The Mineralocorticoids – aldosterone is secreted by
the adrenal cortex. It regulates electrolyte and water balance
by promoting sodium and chloride retention and potassium
excretion.
i. Hyposecretion – results in a reduced plasma volume.
ii. Hypersecretion – results in primary aldosteronism.
ANATOMY AND PHYSIOLOGY FOR ICD-10
THE ENDOCRINE SYSTEM
c. The Androgens – hormones that promote the development
of male characteristics. The two main androgen hormones are
testosterone and androsterone. They are responsible for
development of the male secondary sex characteristics.
2. The Adrenal Medulla – synthesizes, secretes, and
stores catecholamines, specifically the following:
a. Dopamine – dilates systemic arteries, elevates blood
pressure (BP), increases cardiac output, and increases urinary
output.
b. Epinephrine – Adrenalin or adrenaline, acts as a
vasoconstrictor, vasopressor, cardiac stimulant, antispasmodic,
and sympathomimetic. Its main function is to assist in the
regulation of the sympathetic branch of the autonomic nervous
system.
c. Norepinephrine – noradrenaline, acts as a
vasoconstrictor, vasopressor, and neurotransmitter. It elevates
systolic and diastolic blood pressure (BP), increases the heart
rate and cardiac output and increases glycogenolysis.
G. The Ovaries – the hormones produced by the ovaries are
essential for promoting growth, development, and the maintenance
of secondary female sex organs and characteristics. They also
ANATOMY AND PHYSIOLOGY FOR ICD-10
THE ENDOCRINE SYSTEM
prepare the uterus for pregnancy, promote development of the
mammary glands, and play a vital role in a woman’s emotional
well being and her sexual drive. The hormones produced are:
1. Estrogens (estradiol, estrone, and estriol) – the
female sex hormone secreted by the graafian follicles of the
ovaries.
2. Progesterone – a steroid hormone secreted by the
corpus luteum.
H. The Testes – produce testosterone, which is essential
for normal growth and development of the male accessory sex
organs. Testosterone plays a role in the erection process of the
penis.
I. The Placenta – the spongy structure which joins the
mother and child. It produces chorionic gonadotropin hormone,
estrogen, and progesterone.
J. The Gastrointestinal Mucosa
1. Gastrin – secreted by the mucosa of the pyloric area
of the stomach and stimulates gastric acid secretion.
2. Secretin – secreted by the mucosa of the duodenum and
jejunum and stimulates pancreatic juices, bile, and intestinal
secretions.
ANATOMY AND PHYSIOLOGY FOR ICD-10
THE ENDOCRINE SYSTEM
3. Pancreozymin-cholecystokinin – secreted by the mucosa
of the duodenum and stimulates the pancreas.
4. Enterogastrone – secreted by the mucosa of the
duodenum and regulates gastric secretions.
K. The Thymus – a bilobed body located in the mediastinal
cavity. It is composed of lymphoid tissue and is a part of the
lymphatic system. This ductless gland-like body secretes:
1. Thymosin – promotes the maturation process of T
lymphocytes.
2. Thymopoietin – hormone that influences production of
lymphocyte precursors and aids them in their process of becoming
T lymphocytes.
II. Life Span Considerations
A. The Child – most structures and glands of the
endocrine system are developed during the first 3 months of
pregnancy. Either excessive high or insufficient production of
growth hormone (GH) by the anterior lobe of the pituitary gland
can cause abnormal growth patterns. Excessive production of GH
can cause gigantism; insufficient production of GH can cause
dwarfism.
ANATOMY AND PHYSIOLOGY FOR ICD-10
THE ENDOCRINE SYSTEM
1. Diabetes Mellitus – most common endocrine system
disorder of childhood. Symptoms include:
a. Polyuria (frequent urination)
b. Polydipsia (excessive thirst)
c. Polyphagia (extreme hunger)
B. The Older Adult – hormonal changes vary with each
individual. Tissue receptors decrease, thus diminishing the
body’s response to hormones. Type 2 diabetes mellitus in the
older adult occurs because the amount of insulin produced by the
body is sufficient, but the number of receptors is reduced. This
results in the inability of glucose to enter the cells.
III. Terminology
A. Medical Words and Definitions with Word Parts – these
terms (shown in black in the Building Your Medical Vocabulary
feature) can be analyzed and defined by dividing them into
component parts.
1. Prefixes
2. Word Roots
3. Combining Forms
4. Suffixes
5. Pathology Spotlight
ANATOMY AND PHYSIOLOGY FOR ICD-10
THE ENDOCRINE SYSTEM
a. Diabetes (p. 371) (See PowerPoint presentation on the
accompanying IRCD to view a video on the topic of diabetes)–
Diabetes Mellitus is a complex disorder of metabolism. It is a
disease in which the body does not produce or properly use
insulin. There are three major types:
i. Type 1 diabetes – results from the body’s failure
to produce insulin. An individual with this type of diabetes
will need to take insulin injections each day for the rest of
his or her life. It is estimated that 5–10% of Americans with
diabetes have Type 1 diabetes.
ii. Type 2 diabetes – is the most common type. It results
from insulin resistance combined with relative insulin
deficiency. Type 2 diabetes used to be rare in children, but
with the increase in obesity in children, 1 out of 20 children
who have diabetes has type 2. Of these children, 85% are obese.
Even modest lifestyle changes can help prevent the onset of Type
2 diabetes. The key is to eat a healthy diet, exercise 30
minutes a day at least 5 days a week, and maintain a proper body
weight for age and body type.
ANATOMY AND PHYSIOLOGY FOR ICD-10
THE ENDOCRINE SYSTEM
iii. Gestational Diabetes – or pregnancy-induced diabetes
develops in a pregnant woman. In most cases, this type of
diabetes goes away after the woman’s child is born.
(Table 11-2, p. 372)
b. Hyperthyroidism (p. 373) (See PowerPoint presentation
on the accompanying IRCD to view a video on the topic of
hyperthyroidism)– condition caused by elevated levels of thyroid
hormone.
i. Graves’ Disease – an autoimmune disease in which
antibodies produced by the immune system stimulate the thyroid
to produce too much thyroxine.
ii. Thyroiditis – inflammation of the thyroid gland
iii. Tumors of the Thyroid Gland
c. Hypothyroidism (p. 372) (See PowerPoint presentation
on the accompanying IRCD to view a video on the topic of
hypothyroidism)– a condition in which the thyroid gland does not
produce adequate amounts of thyroid hormone.
i. Goiter – enlargement of the thyroid gland most often
caused by Hashimoto’s thyroiditis, an autoimmune inflammation of
the thyroid.
ANATOMY AND PHYSIOLOGY FOR ICD-10
THE ENDOCRINE SYSTEM
ii. Myxedema – a rare, life-threatening condition that is
the result of long-term, undiagnosed hypothyroidism.
B. Medical Words and Definitions without Word Parts –
these terms (shown in pink in the Building Your Medical
Vocabulary feature) are not usually analyzed and defined by
dividing them into component parts.
1. Pathology Spotlight
a. Addison’s Disease (p. 371) – occurs when the cortex of
the adrenal gland is damaged and there is a deficiency in the
production of the adrenocortical hormones. It is most commonly
caused by the body attacking itself (autoimmune disease).
C. Pathology Checkpoint
IV. Drug Highlights
A. Thyroid Hormones – increase metabolic rate, cardiac
output, O2 consumption, body temperature, respiratory rate,
blood volume, and carbohydrate, fat, and protein metabolism, and
influence growth and development at cellular level. Thyroid
hormones are used as supplements or replacement therapy in
hypothyroidism, myxedema, and cretinism.
B. Antithyroid Hormones – inhibit the synthesis of
thyroid hormones by decreasing iodine use in manufacture of
ANATOMY AND PHYSIOLOGY FOR ICD-10
THE ENDOCRINE SYSTEM
thyroglobin and iodothyronine. They do not inactivate or
inhibit thyroxine or triiodothyronine. They are used in the
treatment of hyperthyroidism.
C. Insulin – stimulates carbohydrate metabolism by
increasing the movement of glucose and other monosaccharides
into cells. It also influences fat and carbohydrates metabolism
in the liver and adipose cells. It decreases blood sugar,
phosphate, and potassium, and increases blood pyruvate and
lactate. Insulin is used in the treatment of insulin-dependent
diabetes mellitus, non-insulin-dependent diabetes mellitus when
other regimes are not effective, and to treat ketoacidosis.
D. Insulin Preparations – insulin is given by
subcutaneous injection and is available in rapid-acting,
intermediate-acting, and long-acting preparations.
E. Oral Hypoglycemic – agents of the sulfonylurea class
and are used to stimulate insulin secretions from pancreatic
cells in non-insulin-dependent diabetes with some pancreatic
function.
V. Diagnostic and Laboratory Tests
ANATOMY AND PHYSIOLOGY FOR ICD-10
THE ENDOCRINE SYSTEM
A. Catcholamines – a test performed on urine to determine
the amount of epinephrine and norepinephrine present. These
adrenal hormones increase in times of stress.
B. Corticotropin, Corticotropin-releasing Factor (CRF) –
a test performed on blood plasma to determine the amount of
corticotropin present. Increased levels may indicate stress,
adrenal cortical hypofunction, and/or pituitary tumors.
Decreased levels may indicate adrenal neoplasms and/or Cushing’s
syndrome.
C. Fasting Blood Sugar (FBS) – a test performed on blood
to determine the level of sugar in the bloodstream. Increased
levels may indicate diabetes mellitus, diabetic acidosis, and
many other conditions. Decreased levels may indicate
hypoglycemia, hyperinsulinism, and many other conditions.
D. Glucose Tolerance Test (GTT) – a blood sugar test
performed at specific intervals after the patient has been given a
certain amount of glucose. Blood samples are drawn, and the blood
glucose level of each sample is determined. It is more accurate
than any other blood sugar test, and is used to diagnose diabetes
mellitus.
ANATOMY AND PHYSIOLOGY FOR ICD-10
THE ENDOCRINE SYSTEM
E. 17-hydroxycorticosteroids (17-OHCS) – a test performed
on urine to identify adrenocorticosteroid hormones. It is used
to determine adrenal cortical function.
F. 17-ketosteroids (17-KS) – a test performed on urine to
determine the amount of 17 KS present. 17-KS is the end product
of androgens and is secreted from the adrenal glands and testes.
It is used in the diagnosing of adrenal tumors.
G. Protein-Bound Iodine (PBI) – a test performed on serum
to indicate the amount of iodine that is attached to serum
protein. It may be used to indicate thyroid function.
H. Radioactive Iodine Uptake (RAIU) – a test to measure
the ability of the thyroid gland to concentrate ingested iodine.
Increased level may indicate hyperthyroidism, cirrhosis, and/or
thyroiditis. Decreased level may indicate hypothyroidism.
I. Radioimmunoassay – a standard assay method that is
used for the measurement of minute quantities of specific
antibodies and/or antigens. It may be used for clinical
laboratory measurements of hormones, therapeutic drug
monitoring, and substance abuse screening.
J. Thyroid Scan – a test to detect tumors of the thyroid
gland. The patient is given radioactive iodine 131, which
ANATOMY AND PHYSIOLOGY FOR ICD-10
THE ENDOCRINE SYSTEM
localizes in the thyroid gland, and the gland is then visualized
with a scanner device.
K. Thyroxine (T4) – a test performed to determine the
amount of throxine present. Increased levels may indicate
hyperthyroidism. Decreased levels may indicate hypothyroidism.
L. Triiodothyronine Uptake (T3) – a test performed on
blood serum to determine the amount of triiodothyronine present.
Increased levels may indicate thyrotoxicosis, toxic adenoma,
and/or Hashimoto’s struma. Decreased levels may indicate
starvation, severe infection, and severe trauma.
M. Total Calcium – a test performed on blood serum to
determine the amount of calcium present. Increased levels may
indicate hyperparathyroidism. Decreased levels may indicate
hypoparathyroidism.
N. Ultrasonography – the use of high-frequency sound
waves to visualize the structure being studied. May be used to
visualize the pancreas, thyroid, and any other gland. It is used
as a screening test or as a diagnostic tool.
VI. Abbreviations (p. 377)
VII. Study and Review
ANATOMY AND PHYSIOLOGY FOR ICD-10
THE ENDOCRINE SYSTEM
MedMedia
www.prenhall.com/rice
activities for this chapter can be found on the Companion
Website. For Terminology Translator, animations, video, audio
glossary, and review, access the CD-ROM that accompanies the
student textbook.
POST TEST A
Part I Multiple Choice
DIRECTIONS: Select the best answer to each multiple choice
question and write the appropriate letter on the answer sheet.
1. The _____ gland is known as the master gland of the
body.
a. pineal
b. thyroid
c. pituitary
d. adrenal
ANATOMY AND PHYSIOLOGY FOR ICD-10
THE ENDOCRINE SYSTEM
2. Prolactin is secreted by the:
a. neurohypophysis
b. pineal gland
c. ovaries
d. adenohypophysis
3. The _____ gland plays a vital role in metabolism and
regulates the body’s metabolic processes.
a. thyroid
b. parathyroid
c. pineal
d. pituitary
ANATOMY AND PHYSIOLOGY FOR ICD-10
THE ENDOCRINE SYSTEM
4. _____ is essential for maintenance of a normal level
of blood sugar.
a. Cortisol
b. Insulin
c. Parahormone
d. Serotonin
5. The principle mineralocorticoid secreted by the
adrenal cortex is:
a. aldosterone
b. androgen
c. oxytocin
d. dopamine
6. All are true statements concerning epinephrine except:
ANATOMY AND PHYSIOLOGY FOR ICD-10
THE ENDOCRINE SYSTEM
a. it elevates the systolic blood pressure
b. it decreases the heart rate and cardiac output
c. it dilates the bronchial tubes
d. it dilates the pupils
7. An enlargement of the extremities due to excessive
growth hormone is called:
a. cretinism
b. dwarfism
c. acromegaly
d. gigantism
8. The _____ is the primary link between the endocrine
and nervous sytem.
ANATOMY AND PHYSIOLOGY FOR ICD-10
THE ENDOCRINE SYSTEM
a. pineal
b. hypothalamus
c. hypophysis
d. pituitary
9. _____ is any disease of the adrenal gland.
a. Adrenopathy
b. Adenopathy
c. Adrenotropic
d. Adenalgia
10. A congenital deficiency in secretion of the thyroid
hormone is called:
a. diabetes
ANATOMY AND PHYSIOLOGY FOR ICD-10
THE ENDOCRINE SYSTEM
b. hirsutism
c. gigantism
d. cretinism
11. A physician who specializes in the study of the
endocrine system is known as a/an
a. endocrinology
b. endocrinologist
c. pathologist
d. gastroenterologist
12. _____ means an abnormal protrusion of the eye.
a. Exopthalmic
b. Exocrine
c. Exophthalmic
ANATOMY AND PHYSIOLOGY FOR ICD-10
THE ENDOCRINE SYSTEM
d. Endocrine
13. Excessive secretion of milk after cessation of nursing
is:
a. galactorrhea
b. mammorrhea
c. glandular
d. galactin
14. The medical term for pertaining to drowsiness,
sluggish is:
a. pallor
b. myxedema
c. ascites
d. lethargic
ANATOMY AND PHYSIOLOGY FOR ICD-10
THE ENDOCRINE SYSTEM
15. The pituitary gland is also known as the:
a. pineal
b. hypophysis
c. parathyroid
d. pituitarism
16. _____ is a condition of premature old age occurring in
children.
a. Virilism
b. Progesterone
c. Progeria
d. Vasopressin
ANATOMY AND PHYSIOLOGY FOR ICD-10
THE ENDOCRINE SYSTEM
17. Thymosin promotes the maturation process of:
a. monocytes
b. T lymphocytes
c. B lymphocytes
d. NK cells
18. The surgical excision of the thyroid gland is called:
a. thyroidotomy
b. thyroidotome
c. thyrotherapy
d. thyroidectomy
19. _____ are biochemical substances, epinephrine,
norepinephrine, and dopamine.
ANATOMY AND PHYSIOLOGY FOR ICD-10
THE ENDOCRINE SYSTEM
a. Catecholamines
b. Steroids
c. Hormones
d. Iodines
20. The word root creat means:
a. cretin
b. secrete
c. milk
d. flesh
21. The word root kal means:
a. calcium
b. iron
ANATOMY AND PHYSIOLOGY FOR ICD-10
THE ENDOCRINE SYSTEM
c. potassium
d. magnesium
22. The suffix -in means:
a. fixation
b. chemical
c. disease
d. resemble
23. The ovaries produce all of the following except:
a. androgen
b. estrogen
c. progesterone
d. estrone
ANATOMY AND PHYSIOLOGY FOR ICD-10
THE ENDOCRINE SYSTEM
24. _____ is a gland that produces an internal secretion.
a. Exocrine
b. Enzyme
c. Ectropion
d. Endocrine
25. _____ is used as an anti-inflammatory agent.
a. Aldosterone
b. Cortisone
c. Dopamine
d. Somatotropin
Part II Matching
ANATOMY AND PHYSIOLOGY FOR ICD-10
THE ENDOCRINE SYSTEM
DIRECTIONS: Using the answer sheet, write the letter of the
definition that best matches the word.
26. adenoma
27. adrenal
28. diabetes
29. gigantism
30. hirsutism
31. hyperkalemia
32. hypogonadism
33. oxytocin
34. parathyroid
35. thyroid
36. virilism
37. vasopressin
38. epinephrine
39. dwarfism
40. testosterone a. Also called ADH
b. A condition of being abnormally small
c. Stimulates uterine contraction during childbirth
ANATOMY AND PHYSIOLOGY FOR ICD-10
THE ENDOCRINE SYSTEM
d. A condition of being abnormally large
e. Excessive amounts of potassium in the blood
f. A tumor of a gland
g. Also called adrenaline
h. Toward the kidney
i. Male sex hormone
j. Masculinity developed in a female
k. Hairy condition
l. To go through
m. Deficient internal secretion of the gonads
n. Located beside the thyroid gland
o. Resembling a shield
p. Masculinity developed in a male
Part III Abbreviations: Fill-in-the-Blank
DIRECTIONS: Using the answer sheet, write the correct
abbreviation for each of the following.
41. adrenocorticotropic hormone
ANATOMY AND PHYSIOLOGY FOR ICD-10
THE ENDOCRINE SYSTEM
42. basal metabolic rate
43. diabetes mellitus
44. follicle-stimulating hormone
45. growth hormone
46. somatotropin hormone
47. triiodothyronine
48. thyroxine
49. thyroid function studies
50. thyroid-stimulating hormone
POST TEST B
Part I Word Parts
DIRECTIONS: Using the answer sheet, write the letter of the
definition that best matches the word part.
1. ex-
2. para-
3. pro-
4. acr/o-
ANATOMY AND PHYSIOLOGY FOR ICD-10
THE ENDOCRINE SYSTEM
5. aden-
6. creat-
7. crin/o-
8. dwarf-
9. galact/o-
10. gigant-
11. hirsut-
12. kal-
13. letharg-
14. myx-
15. pituitar-
16. thym-
17. thyr/o-
18. viril-
19. -betes
20. -oid
21. -osis
22. -physis
23. -one
24. -gen
25. -inenda. gland
ANATOMY AND PHYSIOLOGY FOR ICD-10
THE ENDOCRINE SYSTEM
b. milk
c. potassium
d. beside
e. phlegm
f. to go
g. condition of
h. out, away from
i. extremity
j. giant
k. resemble
l. growth
m. before
n. drowsiness
o. thymus
p. hormone
q. pertaining to
r. flesh
s. formation, produce
t. excision
u. to secrete
v. thyroid, shield
ANATOMY AND PHYSIOLOGY FOR ICD-10
THE ENDOCRINE SYSTEM
w. masculine
x. small
y. hairy
z. mucus
Part II Abbreviations: Fill-in-the-Blank
DIRECTIONS: Using the answer sheet, write the correct
abbreviation or meaning for each of the following.
26. ADH
27. diabetes insipidus
28. GTT
29. protein bound iodine
30. RIA
31. PTH
32. LH
33. fasting blood sugar
34. vasopressin
35. BG
ANATOMY AND PHYSIOLOGY FOR ICD-10
THE ENDOCRINE SYSTEM
Part III Multiple Choice
DIRECTIONS: Select the best answer to each multiple choice
question and write the appropriate letter on the answer sheet.
36. The _____ synthesizes and secretes releasing hormones.
a. pineal
b. thyroid
c. hypothalamus
d. adrenal
37. The _____ gland plays a vital role in metabolism.
a. thyroid
b. parathyroid
c. pineal
d. pituitary
ANATOMY AND PHYSIOLOGY FOR ICD-10
THE ENDOCRINE SYSTEM
38. Which disease results from a deficiency in the
secretion of adrenocortical hormones?
a. cretinism
b. hirsutism
c. Addison’s
d. acromegaly
39. In the term androgen, the combining form andr/o means:
a. body
b. self
c. form
d. man
ANATOMY AND PHYSIOLOGY FOR ICD-10
THE ENDOCRINE SYSTEM
40. The suffix -one means:
a. gland
b. enzyme
c. hormone
d. secretion
41. Which disease results from hypersecretion of cortisol?
a. Cushing’s
b. virilism
c. thyrotoxicosis
d. pituitarism
42. In the term estrogen, the combining form estr/o means:
ANATOMY AND PHYSIOLOGY FOR ICD-10
THE ENDOCRINE SYSTEM
a. longing
b. formation
c. produce
d. mad desire
43. In the term norepinephrine, the prefix nor means:
a. without
b. not
c. away from
d. against
44. In the term steroid, the root ster means:
a. structure
b. form
c. solid
ANATOMY AND PHYSIOLOGY FOR ICD-10
THE ENDOCRINE SYSTEM
d. fatty substance
45. A hormone produced by the beta cells of the pancreas
is called:
a. melatonin
b. insulin
c. glucagon
d. calcitonin
46. A test performed on urine to determine the amount of
epinephrine and norepinephrine present is:
a. catecholamines
b. corticotropin
c. protein bound iodine
d. total calcium
ANATOMY AND PHYSIOLOGY FOR ICD-10
THE ENDOCRINE SYSTEM
47. Increased levels of _____ may indicate diabetes
mellitus.
a. thyroid scan
b. total calcium
c. fasting blood sugar
d. protein bound iodine
48. A test used to detect tumors of the thyroid gland is:
a. thyroxine
b. total calcium
c. thyroid scan
d. protein bound iodine
ANATOMY AND PHYSIOLOGY FOR ICD-10
THE ENDOCRINE SYSTEM
49. A blood sugar test that is performed at specified
intervals after the patient has taken glucose is:
a. fasting blood sugar
b. glucose tolerance test
c. protein bound iodine
d. corticotropin
50. A test used in the diagnosing of adrenal tumors is
called:
a. 17-HCS
b. 17-OHCS
c. 17-KS
d. 17-HDL