Aneurysm Model Prototype: Aneurysm Model Prototype: Design Update Design Update

Sara GoldgrabenSara GoldgrabenBill HauserBill Hauser

Michael SavareseMichael Savarese

Advisor: Dr. StreyAdvisor: Dr. StreyCustomer: Dr. ChenCustomer: Dr. Chen

BME 441 DesignBME 441 DesignApril 3, 2006April 3, 2006

OverviewOverview

BackgroundBackgroundOriginal DesignOriginal DesignPre-manufacturing ModificationsPre-manufacturing ModificationsInitial Prototype TestingInitial Prototype TestingPost-Manufacturing ModificationsPost-Manufacturing ModificationsAdditional ModelsAdditional ModelsNear Future ExperimentsNear Future ExperimentsLab SetupLab Setup

BackgroundBackgroundRequired parametersRequired parameters

Aneurysm neck: 4mmAneurysm neck: 4mm Vasculature diameter: 4mmVasculature diameter: 4mm Aneurysm diameter: 7mmAneurysm diameter: 7mm Flow Velocity: 100cm/minFlow Velocity: 100cm/min

Transparent Housing Transparent Housing Optical data acquisitionOptical data acquisition Mechanically strongMechanically strong

Easily DisassembledEasily Disassembled MaintenanceMaintenance Weight measurement of Weight measurement of

polymerpolymer DurableDurable

Water-tight sealsWater-tight seals Seal of aneurysm and Seal of aneurysm and

input/output flowinput/output flow

VersatilityVersatility of Designof Design ReusabilityReusability Variable flowVariable flow

Velocity Velocity

Steady/PulsatileSteady/Pulsatile

Original CAD Original CAD DesignDesign

Size of Size of materialsmaterials PlexiglasPlexiglas O-ringsO-rings

Pre-Manufacturing ModificationsPre-Manufacturing Modifications

Consultation with George Consultation with George LuhrsLuhrsSizes are in closest Sizes are in closest American standard to our American standard to our metric requirementsmetric requirementsOverall Model Stems From Overall Model Stems From 2D Model Idea2D Model Idea

Double PlugDouble Plug Single PlugSingle Plug

Added Handle with gripAdded Handle with gripO-ring Sealed PlugO-ring Sealed PlugHigh Tolerance Machined High Tolerance Machined PlugPlug

New DesignNew Design Size: 5in x 2inSize: 5in x 2in Straight Fluid FlowStraight Fluid Flow Mostly SeamlessMostly Seamless Solid Machined FittingsSolid Machined Fittings

Improvements Over Original Improvements Over Original DesignDesign

Smaller Overall DimensionsSmaller Overall Dimensions Eliminates long entry lengthEliminates long entry length Less Material UsedLess Material Used Less Chance of LeaksLess Chance of Leaks Solid Machined FittingsSolid Machined Fittings

Initial Prototype TestingInitial Prototype Testing

Prototype: High Tolerance FittingPrototype: High Tolerance Fitting

ResultsResults PositivePositive

Water-tightWater-tight

Machined Barbed Fittings Work Well Machined Barbed Fittings Work Well NegativeNegative

Aneurysm CracksAneurysm Cracks

Opaque TintOpaque Tint Requires Further PolishingRequires Further Polishing

Post-Manufacturing ModificationsPost-Manufacturing Modifications

Enlarged PlugEnlarged Plug Larger Aneurysm WallLarger Aneurysm Wall

Will reduce aneurysm weaknessWill reduce aneurysm weakness

Reduction of OpacityReduction of Opacity PolishingPolishing

MechanicalMechanical Cloth TipCloth Tip Wooden Tip (Plausibility not yet known)Wooden Tip (Plausibility not yet known)

Polishing SolutionPolishing Solution

Heat BasedHeat Based BakingBaking Heated Ball BearingsHeated Ball Bearings

Additional ModelsAdditional Models

Lateral Wall Aneurysm ModelsLateral Wall Aneurysm Models 11mm and 13mm Aneurysm11mm and 13mm Aneurysm 4mm vessel4mm vessel

Bifurcated AneurysmBifurcated Aneurysm 10-11mm Aneurysm10-11mm Aneurysm 4mm vessel4mm vessel

Near Future ExperimentsNear Future Experiments

Test Polishing MethodsTest Polishing Methods

Test Model with PolymerTest Model with Polymer Easily Cleaned Easily Cleaned Sufficiently TransparentSufficiently Transparent No Optical ArtifactsNo Optical Artifacts

Lab SetupLab SetupAssemblyAssembly

Safety Precautions Safety Precautions

Barometer set upBarometer set up

Experimental setupsExperimental setups Static flow (reservoir is gravity driven)Static flow (reservoir is gravity driven) Dynamic flow (pump)Dynamic flow (pump)

Closed loopClosed loopOpen loopOpen loop

ConclusionConclusion

Budget BreakdownBudget Breakdown Pump = $400Pump = $400 Plexiglas = $80Plexiglas = $80 Large O-Rings (Not being used) = $35Large O-Rings (Not being used) = $35 Stand/Clamps/etc = $120Stand/Clamps/etc = $120 Total so far = $635Total so far = $635

AcknowledgementsAcknowledgements

Professor Chen – CustomerProfessor Chen – Customer

Professor Strey – AdvisorProfessor Strey – Advisor

George Luhrs – machined our productGeorge Luhrs – machined our product

Lester Orlick – Instructional Support Technician Lester Orlick – Instructional Support Technician CEASCEAS

Greg Pollard – APT InstrumentsGreg Pollard – APT Instruments