12
Cancer Research and Treatment 2004;36(1):19-30 Annual Report 19 2001 Annual Report of the Korea Central Cancer Registry: Based on Registered Data from 134 Hospitals Hai-Rim Shin, M.D., Young-Joo Won, M.R.A., Kyu-Won Jung, M.S. and Jae-Gahb Park, M.D. 134 KCCR-affiliated Hospitals, Korea Central Cancer Registry, National Cancer Center, Goyang, Korea Purpose : To estimate the number of cancer cases during 2001, in Korea, through a nationwide hospital based cancer registration by the Korea Central Cancer Registry (KCCR). Materials and Methods: One hundred and thirty four hospitals participated in the KCCR program in 2001. Cancer cases were coded and classified according to the Interna- tional Classification of Diseases for Oncology 2 nd edition (ICD-O-2). The software program “IARC Check” was used to evaluate the quality of the registered cancer cases. Of the 111,816 malignancies registered, 10,106 (9.0%) dupli- cated malignancies were excluded. Among the remaining 95,542 malignancies, 3,598 (3.8%) cases with carcinoma in situ (Morphology code/2) were separated. Finally, 91,944 malignancies were analyzed. Results: Of the total 91,944 malignancies, 51,753 (56.3%) cases were males and 40,191 (43.7%) were females. More than one third of cases were from the elderly (65 years old and more). The six leading primary cancer sites, in the order of their relative frequency, were stomach (24.1%), followed by the lung (16.0%), the liver (16.0%), the colorectum (10.5%), the bladder (3.4%), and the prostate (2.8%) among males. In females, the breast (16.1%) was the common cancer site, followed by the stomach (15.3%), the colorectum (10.5%), the cervix uteri (10.1%), the thyroid gland (8.3%) and the lung (6.6%). Conclusion: With the continued increase in cancer cases, the total number of registered cancer cases in Korea con- tinues to rapidly increase. (Cancer Research and Treat- ment 2004;36:19-30) Key Words: Cancer registry, Annual report Correspondence: Jae-Gahb Park, National Cancer Center, Goyang-si, Gyeonggi-do 411-769, Korea. (Tel) 82-31-920-2050, (Fax) 82-31- 920-2051, (E-mail) [email protected] This study was supported by The National Cancer Center Grant 0110010. INTRODUCTION The Korea Central Cancer Registry (KCCR) was started as an ambitious project of the Ministry of Health and Welfare in 1980 (1). In the beginning, 47 nationwide resident-training general hospitals participated in this program. The number of participating hospitals and registered malignancies increased year by year, and 134 hospitals submitted their data diskettes in 2001. In 1996, the International Classification of Diseases for Oncology 2 nd edition (ICD-O-2) was translated into Korean and distributed to all the participating hospitals. Topography and Morphology codes of the ICD-O-2 have been used since the 16 th annual report of the KCCR. The aim of this paper is to provide a summary of the 22 nd annual report of the KCCR, which was published in February 2003 (1). It contains the relative frequencies of various cancers in the Republic of Korea, derived from the nationwide database of the hospital-based cancer registry program from January 1, to December 31, 2001. MATERIALS AND METHODS One hundred and thirty four hospitals participated in the KCCR in 2001. All cancer registry data, submitted from the participating hospitals on diskettes during the year, were revi- ewed and sorted by qualified cancer registrars in the National cancer Center. After correction of erroneous coding of topogra- phy and morphology, cancer cases were classified according to the ICD-O-2. To avoid duplication, the computer compared the personal identification number of all subjects. The software program “IARC Check” which was freely distributed by International Association of Cancer Registry (IACR), was used to evaluate the quality of registered cancer cases. The pathologists working at the hospitals where the cases were diagnosed, reviewed the cases with errors shown from “IARC Check” program. Much emphasis was placed on the basis of diagnosis during this selection procedure. Cases diagnosed by histological examination were preferentially chosen. Of 111,816 malignancies registered, 10,106 (9.0%) duplicated malignancies were excluded. Among the remaining 95,542 malignancies, 3,598 (3.8%) cases with carcinoma in situ (Mor- phology code/2) were separated. Finally, 91,944 malignancies were analyzed.

Annual Report 2001 Annual Report of the Korea … Jae-Gahb Park, National Cancer Center, Goyang-si, Gyeonggi-do 411-769, Korea. (Tel) 82-31-920-2050, (Fax) 82-31- 920-2051, (E-mail)

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Cancer Research and Treatment 200436(1)19-30 Annual Report

19

2001 A nnual Report of the K orea C entral C ancer Registry Based on Registered Data from 134 H ospitals

Hai-Rim Shin MD Young-Joo Won MRA Kyu-Won Jung MS and Jae-Gahb Park MD

134 KCCR-affiliated Hospitals Korea Central Cancer Registry National Cancer Center Goyang Korea

Purpose To estimate the number of cancer cases during 2001 in Korea through a nationwide hospital based cancer registration by the Korea Central Cancer Registry (KCCR) Materials and Methods One hundred and thirty four hospitals participated in the KCCR program in 2001 Cancer cases were coded and classified according to the Interna-tional Classification of Diseases for Oncology 2nd edition (ICD-O-2) The software program ldquoIARC Checkrdquo was used to evaluate the quality of the registered cancer cases Of the 111816 malignancies registered 10106 (90) dupli-cated malignancies were excluded Among the remaining 95542 malignancies 3598 (38) cases with carcinoma in situ (Morphology code2) were separated Finally 91944 malignancies were analyzed

Results Of the total 91944 malignancies 51753 (563) cases were males and 40191 (437) were females

More than one third of cases were from the elderly (65 yearsold and more) The six leading primary cancer sites in the order of their relative frequency were stomach (241) followed by the lung (160) the liver (160) the colorectum (105) the bladder (34) and the prostate (28) among males In females the breast (161) was thecommon cancer site followed by the stomach (153) the colorectum (105) the cervix uteri (101) the thyroid gland (83) and the lung (66) Conclusion With the continued increase in cancer cases the total number of registered cancer cases in Korea con-tinues to rapidly increase (Cancer Research and Treat-ment 20043619-30)985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103 Key W ords Cancer registry Annual report

Correspondence Jae-Gahb Park National Cancer Center Goyang-si

Gyeonggi-do 411-769 Korea (Tel) 82-31-920-2050 (Fax) 82-31-

920-2051 (E-mail) hrshinnccrekr

This study was supported by The National Cancer Center Grant 0110010

INTRODUCTION

The Korea Central Cancer Registry (KCCR) was started as an ambitious project of the Ministry of Health and Welfare in 1980 (1) In the beginning 47 nationwide resident-training general hospitals participated in this program The number of participating hospitals and registered malignancies increased year by year and 134 hospitals submitted their data diskettes in 2001 In 1996 the International Classification of Diseases for Oncology 2

nd edition (ICD-O-2) was translated into Korean and

distributed to all the participating hospitals Topography and Morphology codes of the ICD-O-2 have been used since the 16th annual report of the KCCR The aim of this paper is to provide a summary of the 22nd annual report of the KCCR which was published in February 2003 (1) It contains the relative frequencies of various cancers in the Republic of Korea derived from the nationwide database of the hospital-based cancer registry program from January 1

to December 31 2001

MATERIALS AND METHODS

One hundred and thirty four hospitals participated in the KCCR in 2001 All cancer registry data submitted from the participating hospitals on diskettes during the year were revi-ewed and sorted by qualified cancer registrars in the National cancer Center After correction of erroneous coding of topogra-phy and morphology cancer cases were classified according to the ICD-O-2 To avoid duplication the computer compared the personal identification number of all subjects The software program ldquoIARC Checkrdquo which was freely distributed by International Association of Cancer Registry (IACR) was used to evaluate the quality of registered cancer cases The pathologists working at the hospitals where the cases were diagnosed reviewed the cases with errors shown from ldquoIARC Checkrdquo program Much emphasis was placed on the basis of diagnosis during this selection procedure Cases diagnosed by histological examination were preferentially chosen Of 111816 malignancies registered 10106 (90) duplicated malignancies were excluded Among the remaining 95542 malignancies 3598 (38) cases with carcinoma in situ (Mor-phology code2) were separated Finally 91944 malignancies were analyzed

20 Cancer Research and Treatment 200436(1)

Table 1 Frequency of new cancer cases by gender and age in 2001 Korea

985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114 Male Female Total

Age 985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

groupN N N

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103 0 75 01 53 01 128 01

1~4 237 05 172 04 409 04

5~9 189 04 123 03 312 03

10~14 160 03 127 03 287 03

15~19 256 05 246 06 502 05

20~24 298 06 468 12 766 08

25~29 500 10 977 24 1477 16

30~34 869 17 1778 44 2647 29

35~39 1546 30 2801 70 4347 47

40~44 2825 55 4151 103 6976 76

45~49 3962 77 4207 105 8169 89

50~54 5233 101 3954 98 9187 100

55~59 7101 137 4263 106 11364 124

60~64 9071 175 4696 117 13767 150

65~69 8167 158 4521 112 12688 138

70~74 5774 112 3663 91 9437 103

75~79 3583 69 2453 61 6036 66

80~84 1438 28 1044 26 2482 27

85+ 469 09 494 12 963 10985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

All 51753 1000 40191 1000 91944 1000

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103Fig 1 New cancer cases and proportion of cancer cases by major

primary site and gender

RESULTS

1) Marginal frequency of malignant neoplasm and carcinoma in situ by age sex and topography

Of the total 91944 registered malignancies 51753 (563) cases were males and 40191 (437) were females The pro-portion of cancer cases among children (age 0~14) and among the elderly (65 and more) were 11 and 344 respectively (Table 1) The most common 10 primary sites among males were stomach (241) lung (160) liver (160) colorectum (105) blader (34) prostate (28) esophagus (27) hema-topoietic amp reticuloendothelial systems (27) pancreas (23) and kidney (20) Among females they were the breast (161) stomach (153) colorectum (105) cervix uteri (101) thyroid (83) lung (66) liver (65) ovary (38) hematopoietic amp reticuloendothelial systems (27) and pancreas (21) (Fig 1) The most common cancer among children (0~14 years old) was in the hematopoietic amp reticuloendothelial systems with 363 of boys and 341 of girls For the age group 15~34 stomach cancer was the most common cancer among males (179) and thyroid cancer among females (225) For the males in the older age groups the stomach was leading site

of cancer at 261 and 226 among 35~64 year olds and those 65 and over respectively However among the females aged 35~64 breast cancer was the most common cancer (221) with stomach cancer being the most common among those 65 and over (201) (Table 2) Table 3 shows the number of carcinoma in situ cases by gender 416 of registered uterine cervix cases were car-cinomas in situ However only 68 of registered female breast cancer cases were diagnosed as carcinomas in situ

2) Distribution of the six major cancers by topographic and morphologic type

Table 4 shows the primary sites and morphologic types of the six major cancers by gender More than one third of stomach cancer (C16) occurred in the antrum part of the stomach (341 in males and 327 in females respectively) and half of these were adenocarcinomas (524 in males and 490 in females) For bronchus and lung cancers (C34) the major primary site was the upper lobe (316 in males and 263 in females) with squamous cell carcinomas (394) the major morphologic type in males but adenocarcinomas (400) in females In males hepatocellularcarcinomas accounted for 762 of the liver and intrahepatic bile ducts cancers (C22) however in females this was 637 For breast cancer 356 of female breast cancer (C50) occurred in the upper outer part of the breast with 826 being

Table 2 Frequency of major cancer cases by gender and age in 2001 Korea985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114

Male FemaleAge

Rank 985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103group

Site N () Site N ()985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

0~14 1 Hematopoietic 240 (363) Hematopoietic 162 (341)

2 Brain 105 (159) Brain 78 (164)

3 Adrenal gland 42 (64) Adrenal gland 25 (53)

4 Bone and Joints and articular 30 (45) Ovary 24 (51)

cartilage of limbs

5 Testis 29 (44) Bone and Joints and articular 21 (44)

cartilage of limbs

6 Lymph nodes 29 (44) Eye and adnexa 21 (44)

7 Connective subcutaneous and 28 (42) Thyroid gland 19 (40)

other soft tissues

8 Eye and adnexa 27 (41) Kidney 18 (38)

9 Kidney 24 (36) Connective subcutaneous 16 (34)

and other soft tissues

10 Liver and intrahepatic bile ducts 16 (24) Lymph nodes 16 (34)

etc 91 (138) 75 (158)985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Subtotal 675 731

98510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510315~34 1 Stomach 344 (179) Thyroid gland 780 (225)

2 Hematopoietic 266 (138) Breast 611 (176)

3 Liver and intrahepatic bile ducts 154 (80) Stomach 375 (108)

4 Colorectum 132 (69) Cervix uteri 342 (99)

5 Brain 130 (68) Ovary 309 (89)

6 Lymph nodes 123 (64) Hematopoietic 203 (59)

7 Thyroid gland 112 (58) Colorectum 125 (36)

8 Testis 68 (35) Brain 87 (25)

9 Bone and Joints and articular 63 (33) Lymph nodes 66 (19)

cartilage of limbs

10 Bronchus and lung 56 (29) Corpus uteri 53 (15)

etc 475 (247) 518 (149)

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103Subtotal 1836 3521

98510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510335~64 1 Stomach 7747 (261) Breast 5311 (221)

2 Liver and intrahepatic bile ducts 6073 (204) Stomach 3346 (139)

3 Bronchus and lung 3839 (129) Cervix uteri 2987 (124)

4 Colorectum 3265 (110) Colorectum 2188 (91)

5 Bladder 844 (28) Thyroid gland 2161 (90)

6 Esophagus 762 (26) Liver and intrahepatic bile ducts 1450 (60)

7 Kidney 697 (23) Bronchus and lung 1214 (50)

8 Pancreas 656 (22) Ovary 939 (39)

9 Hematopoietic 622 (21) Corpus uteri 565 (24)

10 Larynx 538 (18) Hematopoietic 461 (19)

etc 4695 (158) 3450 (143)985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Subtotal 30752 25994

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Hai-Rim Shin et alAnnual Report of the KCCR-2001 21

22 Cancer Research and Treatment 200436(1)

Table 3 Frequency of primary in-situ cases in 2001 Korea985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114

Male Female Rank 985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103}}}}}}}}985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Malignant in-situ (n=122) Malignant in-situ (n=3476)

Primary site 985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103 Primary site 985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103N () N () N () N ()

9851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851031 Skin 648 (969) 33 (18) Cervix 4061 (584) 2898 (416)

2 Bladder 1734 (992) 29 (31) Breast 6469 (932) 473 (68)

3 Colon 2657 (995) 25 (37) Skin 613 (958) 27 (42)

4 Stomach 12481 (999) 24 (08) Colon 2139 (994) 12 (06)

5 Larynx 923 (989) 20 (02) Vagina 49 (803) 12 (197)

etc 33310 (999) 64 (02) 26860 (998) 54 (02)985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Table 2 Continued 985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114

Male FemaleAge

Rank 985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103group

Site N () Site N ()985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

65+ 1 Stomach 4388 (226) Stomach 2442 (201)

2 Bronchus and lung 4385 (226) Colorectum 1903 (156)

3 Colorectum 2074 (107) Bronchus and lung 1372 (113)

4 Liver and intrahepatic 2018 (104) Liver and intrahepatic 1095 (90)

bile ducts bile ducts

5 Prostate gland 1079 (56) Cervix uteri 731 (60)

6 Bladder 857 (44) Breast 547 (45)

7 Esophagus 657 (34) Pancreas 510 (42)

8 Pancreas 517 (27) Thyroid gland 357 (29)

9 Other and unspecified 436 (22) Gallbladder 339 (28)

parts of biliary tract

10 Larynx 382 (20) Other and unspecified 323 (27)

parts of biliary tract

etc 2638 (136) 2556 (210)985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Subtotal 22135 13599

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

infiltrating duct carcinomas The most common site of colon cancer (C18) was the sigmoid colon (398 in males and 357 in females respectively) and the most frequent morpho-logic type was adenocarcinomas (600 in males and 601 in females) Only 112 of male and 111 of female rectal cancers occurred in the rectosigmoid junction As with other cancers adenocarcinomas were the major morphologic type of rectal cancer (625 in males and 606 in females) Appendix 2 shows the distribution of cancer cases by ICD-10 for easy comparison of the cancer death statistics

DISCUSSION

Information on the incidence and mortality of cancers and their changing trends is an essential component in the planning and monitoring of programs for cancer prevention early dete-ction and treatment (2) The Korea Central Cancer Registry (KCCR) was started as an ambitious project of the Ministry of Health and Welfare

Table 4 Frequency of topography and morphology in major cancer sites985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114

Male Female985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103}}}985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103Topography Cases () Morphology Cases () Topography Cases () Morphology Cases ()985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103Stomach (C16)985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103Gastric antrum 4258 Adenocarcinoma 6539 Gastric antrum 2015 Adenocarcinoma 3020

(341) (524) (327) (490)

Body 2900 Tubular adeno ca 3041 Body 1623 Signet ring cell ca 1315

(232) (244) (263) (213)

Overlapping 1698 Signet ring cell ca 1599 Overlapping 838 Tubular adeno ca 1079

lesion (136) (128) lesion (136) (175)

Cardia NOS 483 Mucinous adeno ca 187 Cardia NOS 170 Mucinous adeno ca 98

(39) (15) (28) (16)

Lesser curvature 394 Papillary adeno ca 95 Lesser curvature 164 Leiomyosarcoma 73

(32) (08) (27) (12)

2748 1020 1357 582

(220) (82) (220) (94)985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103Bronchus and lung (C34)985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103Upper lobe 2617 Squamous cell ca 3266 Upper lobe 693 Adenocarcinoma 1056

(316) (394) (263) (400)

Lower lobe 1773 Adenocarcinoma 1838 Lower lobe 592 Squamous cell ca 349

(214) (222) (224) (132)

Main bronchus 375 Small cell ca 1201 Middle lobe 137 Small cell ca 245

(45) (145) (52) (93)

Middle lobe 312 Bronchiolo-alveolar 68 Main bronchus 73 Bronchiolo-alveolar 104

(38) adeno ca (08) (28) adeno ca (39)

Overlapping lesion 241 Carcinoid tumor 59 Overlapping lesion 71 Acinar cell ca 41

(29) (07) (27) (16)

Lung NOS 2966 1852 Lung NOS 1072 843

(358) (224) (406) (320)985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103Liver and intrahepatic bile ducts (C22)985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103Liver 7062 Hepatocellular ca 6293 Liver 1905 Hepatocellular ca 1654

(855) (762) (734) (637)

Intrahepatic 1199 Cholangiocarcinoma 418 Intrahepatic 690 Cholangiocarcinoma 213

bile duct (145) (51) bile duct (266) (82)

Adenocarcinoma 173 Adenocarcinoma 92

(21) (35)

Combined hepatocellular 27 Hepatoblastoma 10

ca and cholangio ca (03) (04)

Tubular adeno ca 10 Combined hepatocellular 8

Hepatoblastoma (01) ca and cholangio ca (03)

Tubular adeno ca

1330 610

(161) (235)

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Hai-Rim Shin et alAnnual Report of the KCCR-2001 23

24 Cancer Research and Treatment 200436(1)

Table 4 Continued 985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114

Male Female985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103}}}985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103Topography Cases () Morphology Cases () Topography Cases () Morphology Cases ()

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103Breast (C50)985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Upper outer 2300 Infiltrating duct ca 5346

(356) (826)

Overlapping 839 Lobular ca 221

lesion (130) (34)

Upper inner 752 Mucinous adeno ca 144

(116) (22)

Lower outer 371 Medullary ca 116

(57) (18)

Central portion 329 Papillary ca 80

(51) (12)

1878 562

(290) (87)985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103Rectum (C19-C20)985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103Rectum NOS 2501 Adenocarcinoma 1762 Rectum NOS 1850 Adenocarcinoma 1261

(888) (625) (889) (606)

Rectosigmoid 316 Tubular adeno ca 677 Rectosigmoid 232 Tubular adeno ca 478

junction (112) (240) junction (111) (230)

Mucinous adeno ca 73 Mucinous adeno ca 66

(26) (32)

Carcinoid tumor 48 Papillary adeno ca 48

(17) (23)

Papillary adeno ca 48 Carcinoid tumor 28

(17) (13)

209 201

(74) (97)985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103Colon (C18)985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103}Sigmoid colon 1057 Adenocarcinoma 1593 Sigmoid colon 763 Adenocarcinoma 1286

(600) (357) (398) (601)

Ascending colon 494 Tubular adeno ca 559 Ascending colon 517 Tubular adeno ca 431

(186) (210) (242) (201)

Transverse colon 206 Mucinous adeno ca 163 Transverse colon 162 Mucinous adeno ca 149

(78) (61) (76) (70)

Descending colon 152 Papillary adeno ca 67 Cecum 136 Papillary adeno ca 40

(57) (25) (64) (19)

Cecum 126 Malig Lymphoma 26 Descending colon 101 Malig Lymphoma 15

(47) large cell diffuse (10) (47) large cell diffuse (07)

622 249 460 218

(234) (94) (215) (102)

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Hai-Rim Shin et alAnnual Report of the KCCR-2001 25

in 1980 In the beginning 47 nationwide resident-training general hospitals participated in this program The number of participating hospitals and registered malignancies has incre-ased year-by-year with 134 hospitals submitting their data diskettes in 2001 (1) The number of cancer cases in the KCCR for 2000 was assumed to be more than 90 precise for cancer cases with the comparison of the estimated cancer incidence cases (3) using national mortality data and the incidence data from four frontier regional cancer registries including Kangwha Seoul Busan and Daegu in the Cancer Incidence in Five Continents (4) The KCCR database is especially useful for showing the trend of cancer occurrence in Korea as information on the changing trend of cancer incidence over time is an essential component in the planning and monitoring of programs for cancer prevention early detection and treatment Major cancers including stomach lung liver breast and colorectum but with the exception of uterine cervix cancer were increasing (data not shown) For uterine cervix cancer the proportion of carcinoma in-situ cases increased among the registered cases meaning significant uterine cervix cancers were detected at an early stage Currently KCCR being a nationwide hospital-based cancer registry is supporting technically and financially 9 population- based regional registries Seoul Busan Daegu Incheon Gwangju Daejeon Ulsan Jejudo and Goyang-si in 2003 The KCCR database continues to hold the most important position until a nationwide population-based data acquisition program can be constructed on the basis of international standards One area for caution in the interpretation of the KCCR data

is that the numbers outlined in this report do not represent persons but cases that have been reported The patients who had cancers at several sites have been treated as multiple primary patients and have been reported according to the cancer site

ACKNOWLEDGEMENTS

We would like to sincerely thank the participation of the medical record administrators in the KCCR-affiliated hospitals [Appendix 1] who enthusiastically participated in the KCCR by registering new cancer cases We would also like to thank Ji-Young Kim MRA Su-Jin Kim MS Hye-Jin Kim MRA Kwang-Suk Park MRA and Ji-Young Oh MRA for their devoted efforts to mining and clearing the KCCR data set

REFERENCES

1 Ministry Health and Welfare 2001 Annual report of Korea Central Cancer Registry (published in 2003) Available from URLhttpwwwnccrekr

2 WHO IARC Cancer Registration Principles and methods 1991 Lyon France

3 Shin HR Ahn YO Bae JM Shin MH Lee DH Lee CW Ohrr HC Ahn DH Ferlay J Parkin DM Oh DK Park JG Cancer Incidence in Korea Cancer Research and Treatment 2002 405-408

4 WHO IARC Cancer Incidence in Five Continents Volume VIII 2002

Appendix 1 List of the Hospitals participating in the 2001 KCCR program985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114

Ajou University Hospital

Andong General Hospital

Andong Presbyterian Hospital

Ansan Hando General Hospital

Asan Medical Center

Bag Ae Hospital

Benedict Hospital

Bupyeong Serim Hospital

Busan Veterans Hospital

Carollo Hospital

Catholic GEN Hospital

Changwon Fatima Hospital

Changwon General Hospital

ChonBuk National University Hospital

Chongju St Marys Hospital

Chonnam University Hospital

Choon Hae Hospital

Chosun University Hospital

Chung-Ang University Hospital

ChungAng University Medical Center

Chungbuk National University Hospital

Chungnam National University Hospital

College of Medicine Pochon CHA university CHA General Hospital

Dae Dong hospital

Dae Jeon Veterans Hospital

Dae Rim St Marys Hospital

Daegu Medical Center

Daewoo Hospital

DanKook University Hospital

Dong Kang General Hospital

Dong Rae Bong Seng Hospital

Dong-A University Hospital

Dongeui Medical Center

Dongguk University Kyong Ju Hospital

Dong-In Hospital

Dong-Kuk University Po-Hang Hospital

Dongsan Medical Center

Ewha Womans University Mokdong Hospital

Ewha Womans University Tongdaemun Hospital

Gachon Medical School Gil Medical Center

Gangneung Asan Hospital

Gangneung Medical Center

Gyeongsang University Hospital

Hae Dong Hospital

Halla General hospital

Hallym Sacred Heart Hospital

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

26 Cancer Research and Treatment 200436(1)

Appendix 1 Continued

985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114Hallym University Hang Gang Sacred Heart Hospital

Hallym University Medical Center ChunCheon Sacred Heart Hospital

Hangdong University Sunlin Presbyterian Hospital

Hanil Hospital

Hanyang University Hospital

Hanyang University Kuri Hospital

Holy Hamily Hospital

Il Sin Christian Hospital

In Je University Pusan Paik hospital

Inchon Christian Hospital

Inha University Hospital

Inha University Medical Center Inha Hospital

Inje Univ Ilsan Paik Hospital

Inje University Sanggye Paik Hospital

Inje University Seoul Paik Hospital

kang Dong Sacred Heart Hospital

Kangbuk Samsung Hospital

kangnam General Hospital Public Corporation

KangNam Sacred Heart Hospital Hallym University

Keimyung University Medical Center

Kon Kuk University Medical Center Seoul Hospital

Konyang University Hospital

Korea Cancer Center Hospital

Korea University Ansan Hospital

Korea University College of Medicine Guro Hospital

Korea University Hospital

Korea Veterans Hospital

Kosin University Gospel Hospital

Kwaks Hospital

Kwang Ju Christian Hospital

Kwang Ju Veterans Hospital

Kwang Myung Sung Ae General Hospital

Kwanghye General Hospital

Kyung Hee Medical Center

Kyungpook National University Hospital

Local Public Corp Inchun Medical Center

Local Public Corporation Chung Cheong Nam-do Hong Sung Medical Center

Maryknoll General Hospital

Masan Samsung Hospital

Mokpo Catholic Hospital

Moonhwa Hospital

Nam Kwang Hospital

National Cancer Center

National Health Insurance Corporation Ilsan Hospital

National Medical Center

National Police Hospital

Pochon Cha Univ Kumicha medical center

Pohang St Marys Hospital

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Hai-Rim Shin et alAnnual Report of the KCCR-2001 27

28 Cancer Research and Treatment 200436(1)

Appendix 1 Continued

985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114Presbyterian Medical Center

Pundang Je-Saeng Hospital

Pusan Adventist Hospital

Pusan Medical Center

Pusan National University Hospital

Samsun Hospital

Samsung Medical center

Sansung Cheil Hospital amp Womens Health Care Center

Sejong General Hospital

Seo San Medical Center

Seoul Adventist Hospital

Seoul Municipal Boramae Hospital

Seoul National University Hospital

Seoul Red Cross Hospital

Severance Hospital Yonsei University Medical College

Shin Chun Hospital

Soonchunhyang GuMi Hospital

Soonchunhyang University Cheonan Hospital

Soonchunyang Univ Hospital

St Marys hospital The Catholic University of Korea

St Francisco General Hospital

St Pauls Hospital

Sun General Hospital

Sung Ae Hospital

Taeback Choongang General Hospital

Taegu Catholic University Hospital

Taegu Fatima Hospital

The Catholic University of Korea Kangnam St Marys Hospital

The Catholic University of Korea Taejon St Marys Hospital

The Catholic University of Korea Our Lady of mercy Hospital

The Catholic University of Korea St Vincents Hospital

Uijongbu St Marys Hospital The Catholic University of Korea

Ulsan University Hospital

Wallace Memorial Baptist Hospital

WonJu Christian Hospital Won Ju Clooege of Medicine Yonsei University

WonKwang University Hospital

Yeungnam University Medical Center

Yeungnam University Youngchun Hospital

Yonsei Medical center Yong-Dong Severance Hospital

Young Dong Hospital985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Appendix 2 Marginal frequency of malignant cases by sexgender and ICD-10 grouping in 2001985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114

Male FemaleSite (code) 985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103}}}}}985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

n n 985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Lip (C00) 17 00 11 00

Tongue (C01~02) 209 04 79 02

Mouth (C03~06) 242 05 99 02

Salivary glands (C07~08) 136 03 107 03

Tonsil (C09) 109 02 15 00

Other oropharynx (C10) 46 01 6 00

Nasopharynx (C11) 218 04 81 02

Hypopharynx (C12~13) 239 05 14 00

Pharynx unspecified (C14) 27 01 3 00

Oesophagus (C15) 1416 27 120 03

Stomach (C16) 12356 239 6050 151

Small intestine (C17) 204 04 140 03

Colon (C18) 2620 51 2112 53

Rectum (C19~20) 2814 54 2073 52

Anus (C21) 59 01 62 02

Liver (C22) 8259 160 2596 65

Gallbladder etc(C23~24) 1361 26 1241 31

Pancreas (C25) 1187 23 854 21

Nose sinuses etc(C30~31) 148 03 81 02

Larynx (C32) 920 18 71 02

TrecheaTrachea bronchus and lung (C33~34) 8292 160 2632 65

Other thoracic organs (C37~38) 157 03 89 02

Bone (C40~41) 218 04 191 05

Melanoma of skin (C43) 112 02 111 03

Other skin (C44) 509 10 493 12

Mesothelioma (C45) 27 01 11 00

Kaposi sarcoma (C46) 7 00 6 00

Connective and soft tissue (C47~49) 294 06 251 06

Breast (C50) 36 01 6459 161

Vulva (C51) - - 67 02

Vagina (C52) - - 48 01

Cervix uteri (C53) - - 4054 101

Corpus uteri (C54) - - 739 18

Uterus unspecified (C55) - - 61 02

Ovary (C56) - - 1520 38

Other female genital organs (C57) - - 34 01

Placenta (C58) 0 00 69 02

Penis (C60) 44 01 - -

Prostate (C61) 1466 28 - -

Testis (C62) 133 03 - -

Other male genital organs (C63) 28 01 - -

Kidney (C64) 1011 20 465 12

Renal pelvis (C65) 128 02 29 01

Ureter (C66) 117 02 62 02

Bladder (C67) 1730 33 415 10

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Hai-Rim Shin et alAnnual Report of the KCCR-2001 29

Appendix 2 Continued985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114

Male FemaleSite (code) 985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103}}}}}}}}}985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

n n 985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Other urinary organs (C68) 21 00 24 01

Eye (C69) 51 01 40 01

Brain nervous system (C70~72) 609 12 489 12

Thyroid (C73) 551 11 3305 82

Adrenal gland (C74) 71 01 48 01

Other endocrine (C75) 46 01 20 00

Hodgkin disease (C81) 92 02 42 01

Non-Hodgkin lymphoma (C82~85 C96) 1185 23 793 20

Immunoproliferative diseases (C88) 9 00 0 00

Multiple myeloma (C90) 267 05 202 05

Lymphoid leukaemia (C91) 290 06 194 05

Myeloid leukaemia (C92~94) 645 12 555 14

Leukaemia unspecified (C95) 39 01 39 01

Other and unspecified 981 19 819 20 (C26 C39 C48 C76 C80 C97)

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

30 Cancer Research and Treatment 200436(1)

20 Cancer Research and Treatment 200436(1)

Table 1 Frequency of new cancer cases by gender and age in 2001 Korea

985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114 Male Female Total

Age 985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

groupN N N

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103 0 75 01 53 01 128 01

1~4 237 05 172 04 409 04

5~9 189 04 123 03 312 03

10~14 160 03 127 03 287 03

15~19 256 05 246 06 502 05

20~24 298 06 468 12 766 08

25~29 500 10 977 24 1477 16

30~34 869 17 1778 44 2647 29

35~39 1546 30 2801 70 4347 47

40~44 2825 55 4151 103 6976 76

45~49 3962 77 4207 105 8169 89

50~54 5233 101 3954 98 9187 100

55~59 7101 137 4263 106 11364 124

60~64 9071 175 4696 117 13767 150

65~69 8167 158 4521 112 12688 138

70~74 5774 112 3663 91 9437 103

75~79 3583 69 2453 61 6036 66

80~84 1438 28 1044 26 2482 27

85+ 469 09 494 12 963 10985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

All 51753 1000 40191 1000 91944 1000

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103Fig 1 New cancer cases and proportion of cancer cases by major

primary site and gender

RESULTS

1) Marginal frequency of malignant neoplasm and carcinoma in situ by age sex and topography

Of the total 91944 registered malignancies 51753 (563) cases were males and 40191 (437) were females The pro-portion of cancer cases among children (age 0~14) and among the elderly (65 and more) were 11 and 344 respectively (Table 1) The most common 10 primary sites among males were stomach (241) lung (160) liver (160) colorectum (105) blader (34) prostate (28) esophagus (27) hema-topoietic amp reticuloendothelial systems (27) pancreas (23) and kidney (20) Among females they were the breast (161) stomach (153) colorectum (105) cervix uteri (101) thyroid (83) lung (66) liver (65) ovary (38) hematopoietic amp reticuloendothelial systems (27) and pancreas (21) (Fig 1) The most common cancer among children (0~14 years old) was in the hematopoietic amp reticuloendothelial systems with 363 of boys and 341 of girls For the age group 15~34 stomach cancer was the most common cancer among males (179) and thyroid cancer among females (225) For the males in the older age groups the stomach was leading site

of cancer at 261 and 226 among 35~64 year olds and those 65 and over respectively However among the females aged 35~64 breast cancer was the most common cancer (221) with stomach cancer being the most common among those 65 and over (201) (Table 2) Table 3 shows the number of carcinoma in situ cases by gender 416 of registered uterine cervix cases were car-cinomas in situ However only 68 of registered female breast cancer cases were diagnosed as carcinomas in situ

2) Distribution of the six major cancers by topographic and morphologic type

Table 4 shows the primary sites and morphologic types of the six major cancers by gender More than one third of stomach cancer (C16) occurred in the antrum part of the stomach (341 in males and 327 in females respectively) and half of these were adenocarcinomas (524 in males and 490 in females) For bronchus and lung cancers (C34) the major primary site was the upper lobe (316 in males and 263 in females) with squamous cell carcinomas (394) the major morphologic type in males but adenocarcinomas (400) in females In males hepatocellularcarcinomas accounted for 762 of the liver and intrahepatic bile ducts cancers (C22) however in females this was 637 For breast cancer 356 of female breast cancer (C50) occurred in the upper outer part of the breast with 826 being

Table 2 Frequency of major cancer cases by gender and age in 2001 Korea985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114

Male FemaleAge

Rank 985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103group

Site N () Site N ()985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

0~14 1 Hematopoietic 240 (363) Hematopoietic 162 (341)

2 Brain 105 (159) Brain 78 (164)

3 Adrenal gland 42 (64) Adrenal gland 25 (53)

4 Bone and Joints and articular 30 (45) Ovary 24 (51)

cartilage of limbs

5 Testis 29 (44) Bone and Joints and articular 21 (44)

cartilage of limbs

6 Lymph nodes 29 (44) Eye and adnexa 21 (44)

7 Connective subcutaneous and 28 (42) Thyroid gland 19 (40)

other soft tissues

8 Eye and adnexa 27 (41) Kidney 18 (38)

9 Kidney 24 (36) Connective subcutaneous 16 (34)

and other soft tissues

10 Liver and intrahepatic bile ducts 16 (24) Lymph nodes 16 (34)

etc 91 (138) 75 (158)985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Subtotal 675 731

98510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510315~34 1 Stomach 344 (179) Thyroid gland 780 (225)

2 Hematopoietic 266 (138) Breast 611 (176)

3 Liver and intrahepatic bile ducts 154 (80) Stomach 375 (108)

4 Colorectum 132 (69) Cervix uteri 342 (99)

5 Brain 130 (68) Ovary 309 (89)

6 Lymph nodes 123 (64) Hematopoietic 203 (59)

7 Thyroid gland 112 (58) Colorectum 125 (36)

8 Testis 68 (35) Brain 87 (25)

9 Bone and Joints and articular 63 (33) Lymph nodes 66 (19)

cartilage of limbs

10 Bronchus and lung 56 (29) Corpus uteri 53 (15)

etc 475 (247) 518 (149)

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103Subtotal 1836 3521

98510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510335~64 1 Stomach 7747 (261) Breast 5311 (221)

2 Liver and intrahepatic bile ducts 6073 (204) Stomach 3346 (139)

3 Bronchus and lung 3839 (129) Cervix uteri 2987 (124)

4 Colorectum 3265 (110) Colorectum 2188 (91)

5 Bladder 844 (28) Thyroid gland 2161 (90)

6 Esophagus 762 (26) Liver and intrahepatic bile ducts 1450 (60)

7 Kidney 697 (23) Bronchus and lung 1214 (50)

8 Pancreas 656 (22) Ovary 939 (39)

9 Hematopoietic 622 (21) Corpus uteri 565 (24)

10 Larynx 538 (18) Hematopoietic 461 (19)

etc 4695 (158) 3450 (143)985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Subtotal 30752 25994

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Hai-Rim Shin et alAnnual Report of the KCCR-2001 21

22 Cancer Research and Treatment 200436(1)

Table 3 Frequency of primary in-situ cases in 2001 Korea985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114

Male Female Rank 985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103}}}}}}}}985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Malignant in-situ (n=122) Malignant in-situ (n=3476)

Primary site 985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103 Primary site 985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103N () N () N () N ()

9851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851031 Skin 648 (969) 33 (18) Cervix 4061 (584) 2898 (416)

2 Bladder 1734 (992) 29 (31) Breast 6469 (932) 473 (68)

3 Colon 2657 (995) 25 (37) Skin 613 (958) 27 (42)

4 Stomach 12481 (999) 24 (08) Colon 2139 (994) 12 (06)

5 Larynx 923 (989) 20 (02) Vagina 49 (803) 12 (197)

etc 33310 (999) 64 (02) 26860 (998) 54 (02)985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Table 2 Continued 985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114

Male FemaleAge

Rank 985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103group

Site N () Site N ()985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

65+ 1 Stomach 4388 (226) Stomach 2442 (201)

2 Bronchus and lung 4385 (226) Colorectum 1903 (156)

3 Colorectum 2074 (107) Bronchus and lung 1372 (113)

4 Liver and intrahepatic 2018 (104) Liver and intrahepatic 1095 (90)

bile ducts bile ducts

5 Prostate gland 1079 (56) Cervix uteri 731 (60)

6 Bladder 857 (44) Breast 547 (45)

7 Esophagus 657 (34) Pancreas 510 (42)

8 Pancreas 517 (27) Thyroid gland 357 (29)

9 Other and unspecified 436 (22) Gallbladder 339 (28)

parts of biliary tract

10 Larynx 382 (20) Other and unspecified 323 (27)

parts of biliary tract

etc 2638 (136) 2556 (210)985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Subtotal 22135 13599

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

infiltrating duct carcinomas The most common site of colon cancer (C18) was the sigmoid colon (398 in males and 357 in females respectively) and the most frequent morpho-logic type was adenocarcinomas (600 in males and 601 in females) Only 112 of male and 111 of female rectal cancers occurred in the rectosigmoid junction As with other cancers adenocarcinomas were the major morphologic type of rectal cancer (625 in males and 606 in females) Appendix 2 shows the distribution of cancer cases by ICD-10 for easy comparison of the cancer death statistics

DISCUSSION

Information on the incidence and mortality of cancers and their changing trends is an essential component in the planning and monitoring of programs for cancer prevention early dete-ction and treatment (2) The Korea Central Cancer Registry (KCCR) was started as an ambitious project of the Ministry of Health and Welfare

Table 4 Frequency of topography and morphology in major cancer sites985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114

Male Female985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103}}}985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103Topography Cases () Morphology Cases () Topography Cases () Morphology Cases ()985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103Stomach (C16)985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103Gastric antrum 4258 Adenocarcinoma 6539 Gastric antrum 2015 Adenocarcinoma 3020

(341) (524) (327) (490)

Body 2900 Tubular adeno ca 3041 Body 1623 Signet ring cell ca 1315

(232) (244) (263) (213)

Overlapping 1698 Signet ring cell ca 1599 Overlapping 838 Tubular adeno ca 1079

lesion (136) (128) lesion (136) (175)

Cardia NOS 483 Mucinous adeno ca 187 Cardia NOS 170 Mucinous adeno ca 98

(39) (15) (28) (16)

Lesser curvature 394 Papillary adeno ca 95 Lesser curvature 164 Leiomyosarcoma 73

(32) (08) (27) (12)

2748 1020 1357 582

(220) (82) (220) (94)985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103Bronchus and lung (C34)985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103Upper lobe 2617 Squamous cell ca 3266 Upper lobe 693 Adenocarcinoma 1056

(316) (394) (263) (400)

Lower lobe 1773 Adenocarcinoma 1838 Lower lobe 592 Squamous cell ca 349

(214) (222) (224) (132)

Main bronchus 375 Small cell ca 1201 Middle lobe 137 Small cell ca 245

(45) (145) (52) (93)

Middle lobe 312 Bronchiolo-alveolar 68 Main bronchus 73 Bronchiolo-alveolar 104

(38) adeno ca (08) (28) adeno ca (39)

Overlapping lesion 241 Carcinoid tumor 59 Overlapping lesion 71 Acinar cell ca 41

(29) (07) (27) (16)

Lung NOS 2966 1852 Lung NOS 1072 843

(358) (224) (406) (320)985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103Liver and intrahepatic bile ducts (C22)985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103Liver 7062 Hepatocellular ca 6293 Liver 1905 Hepatocellular ca 1654

(855) (762) (734) (637)

Intrahepatic 1199 Cholangiocarcinoma 418 Intrahepatic 690 Cholangiocarcinoma 213

bile duct (145) (51) bile duct (266) (82)

Adenocarcinoma 173 Adenocarcinoma 92

(21) (35)

Combined hepatocellular 27 Hepatoblastoma 10

ca and cholangio ca (03) (04)

Tubular adeno ca 10 Combined hepatocellular 8

Hepatoblastoma (01) ca and cholangio ca (03)

Tubular adeno ca

1330 610

(161) (235)

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Hai-Rim Shin et alAnnual Report of the KCCR-2001 23

24 Cancer Research and Treatment 200436(1)

Table 4 Continued 985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114

Male Female985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103}}}985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103Topography Cases () Morphology Cases () Topography Cases () Morphology Cases ()

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103Breast (C50)985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Upper outer 2300 Infiltrating duct ca 5346

(356) (826)

Overlapping 839 Lobular ca 221

lesion (130) (34)

Upper inner 752 Mucinous adeno ca 144

(116) (22)

Lower outer 371 Medullary ca 116

(57) (18)

Central portion 329 Papillary ca 80

(51) (12)

1878 562

(290) (87)985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103Rectum (C19-C20)985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103Rectum NOS 2501 Adenocarcinoma 1762 Rectum NOS 1850 Adenocarcinoma 1261

(888) (625) (889) (606)

Rectosigmoid 316 Tubular adeno ca 677 Rectosigmoid 232 Tubular adeno ca 478

junction (112) (240) junction (111) (230)

Mucinous adeno ca 73 Mucinous adeno ca 66

(26) (32)

Carcinoid tumor 48 Papillary adeno ca 48

(17) (23)

Papillary adeno ca 48 Carcinoid tumor 28

(17) (13)

209 201

(74) (97)985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103Colon (C18)985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103}Sigmoid colon 1057 Adenocarcinoma 1593 Sigmoid colon 763 Adenocarcinoma 1286

(600) (357) (398) (601)

Ascending colon 494 Tubular adeno ca 559 Ascending colon 517 Tubular adeno ca 431

(186) (210) (242) (201)

Transverse colon 206 Mucinous adeno ca 163 Transverse colon 162 Mucinous adeno ca 149

(78) (61) (76) (70)

Descending colon 152 Papillary adeno ca 67 Cecum 136 Papillary adeno ca 40

(57) (25) (64) (19)

Cecum 126 Malig Lymphoma 26 Descending colon 101 Malig Lymphoma 15

(47) large cell diffuse (10) (47) large cell diffuse (07)

622 249 460 218

(234) (94) (215) (102)

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Hai-Rim Shin et alAnnual Report of the KCCR-2001 25

in 1980 In the beginning 47 nationwide resident-training general hospitals participated in this program The number of participating hospitals and registered malignancies has incre-ased year-by-year with 134 hospitals submitting their data diskettes in 2001 (1) The number of cancer cases in the KCCR for 2000 was assumed to be more than 90 precise for cancer cases with the comparison of the estimated cancer incidence cases (3) using national mortality data and the incidence data from four frontier regional cancer registries including Kangwha Seoul Busan and Daegu in the Cancer Incidence in Five Continents (4) The KCCR database is especially useful for showing the trend of cancer occurrence in Korea as information on the changing trend of cancer incidence over time is an essential component in the planning and monitoring of programs for cancer prevention early detection and treatment Major cancers including stomach lung liver breast and colorectum but with the exception of uterine cervix cancer were increasing (data not shown) For uterine cervix cancer the proportion of carcinoma in-situ cases increased among the registered cases meaning significant uterine cervix cancers were detected at an early stage Currently KCCR being a nationwide hospital-based cancer registry is supporting technically and financially 9 population- based regional registries Seoul Busan Daegu Incheon Gwangju Daejeon Ulsan Jejudo and Goyang-si in 2003 The KCCR database continues to hold the most important position until a nationwide population-based data acquisition program can be constructed on the basis of international standards One area for caution in the interpretation of the KCCR data

is that the numbers outlined in this report do not represent persons but cases that have been reported The patients who had cancers at several sites have been treated as multiple primary patients and have been reported according to the cancer site

ACKNOWLEDGEMENTS

We would like to sincerely thank the participation of the medical record administrators in the KCCR-affiliated hospitals [Appendix 1] who enthusiastically participated in the KCCR by registering new cancer cases We would also like to thank Ji-Young Kim MRA Su-Jin Kim MS Hye-Jin Kim MRA Kwang-Suk Park MRA and Ji-Young Oh MRA for their devoted efforts to mining and clearing the KCCR data set

REFERENCES

1 Ministry Health and Welfare 2001 Annual report of Korea Central Cancer Registry (published in 2003) Available from URLhttpwwwnccrekr

2 WHO IARC Cancer Registration Principles and methods 1991 Lyon France

3 Shin HR Ahn YO Bae JM Shin MH Lee DH Lee CW Ohrr HC Ahn DH Ferlay J Parkin DM Oh DK Park JG Cancer Incidence in Korea Cancer Research and Treatment 2002 405-408

4 WHO IARC Cancer Incidence in Five Continents Volume VIII 2002

Appendix 1 List of the Hospitals participating in the 2001 KCCR program985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114

Ajou University Hospital

Andong General Hospital

Andong Presbyterian Hospital

Ansan Hando General Hospital

Asan Medical Center

Bag Ae Hospital

Benedict Hospital

Bupyeong Serim Hospital

Busan Veterans Hospital

Carollo Hospital

Catholic GEN Hospital

Changwon Fatima Hospital

Changwon General Hospital

ChonBuk National University Hospital

Chongju St Marys Hospital

Chonnam University Hospital

Choon Hae Hospital

Chosun University Hospital

Chung-Ang University Hospital

ChungAng University Medical Center

Chungbuk National University Hospital

Chungnam National University Hospital

College of Medicine Pochon CHA university CHA General Hospital

Dae Dong hospital

Dae Jeon Veterans Hospital

Dae Rim St Marys Hospital

Daegu Medical Center

Daewoo Hospital

DanKook University Hospital

Dong Kang General Hospital

Dong Rae Bong Seng Hospital

Dong-A University Hospital

Dongeui Medical Center

Dongguk University Kyong Ju Hospital

Dong-In Hospital

Dong-Kuk University Po-Hang Hospital

Dongsan Medical Center

Ewha Womans University Mokdong Hospital

Ewha Womans University Tongdaemun Hospital

Gachon Medical School Gil Medical Center

Gangneung Asan Hospital

Gangneung Medical Center

Gyeongsang University Hospital

Hae Dong Hospital

Halla General hospital

Hallym Sacred Heart Hospital

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

26 Cancer Research and Treatment 200436(1)

Appendix 1 Continued

985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114Hallym University Hang Gang Sacred Heart Hospital

Hallym University Medical Center ChunCheon Sacred Heart Hospital

Hangdong University Sunlin Presbyterian Hospital

Hanil Hospital

Hanyang University Hospital

Hanyang University Kuri Hospital

Holy Hamily Hospital

Il Sin Christian Hospital

In Je University Pusan Paik hospital

Inchon Christian Hospital

Inha University Hospital

Inha University Medical Center Inha Hospital

Inje Univ Ilsan Paik Hospital

Inje University Sanggye Paik Hospital

Inje University Seoul Paik Hospital

kang Dong Sacred Heart Hospital

Kangbuk Samsung Hospital

kangnam General Hospital Public Corporation

KangNam Sacred Heart Hospital Hallym University

Keimyung University Medical Center

Kon Kuk University Medical Center Seoul Hospital

Konyang University Hospital

Korea Cancer Center Hospital

Korea University Ansan Hospital

Korea University College of Medicine Guro Hospital

Korea University Hospital

Korea Veterans Hospital

Kosin University Gospel Hospital

Kwaks Hospital

Kwang Ju Christian Hospital

Kwang Ju Veterans Hospital

Kwang Myung Sung Ae General Hospital

Kwanghye General Hospital

Kyung Hee Medical Center

Kyungpook National University Hospital

Local Public Corp Inchun Medical Center

Local Public Corporation Chung Cheong Nam-do Hong Sung Medical Center

Maryknoll General Hospital

Masan Samsung Hospital

Mokpo Catholic Hospital

Moonhwa Hospital

Nam Kwang Hospital

National Cancer Center

National Health Insurance Corporation Ilsan Hospital

National Medical Center

National Police Hospital

Pochon Cha Univ Kumicha medical center

Pohang St Marys Hospital

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Hai-Rim Shin et alAnnual Report of the KCCR-2001 27

28 Cancer Research and Treatment 200436(1)

Appendix 1 Continued

985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114Presbyterian Medical Center

Pundang Je-Saeng Hospital

Pusan Adventist Hospital

Pusan Medical Center

Pusan National University Hospital

Samsun Hospital

Samsung Medical center

Sansung Cheil Hospital amp Womens Health Care Center

Sejong General Hospital

Seo San Medical Center

Seoul Adventist Hospital

Seoul Municipal Boramae Hospital

Seoul National University Hospital

Seoul Red Cross Hospital

Severance Hospital Yonsei University Medical College

Shin Chun Hospital

Soonchunhyang GuMi Hospital

Soonchunhyang University Cheonan Hospital

Soonchunyang Univ Hospital

St Marys hospital The Catholic University of Korea

St Francisco General Hospital

St Pauls Hospital

Sun General Hospital

Sung Ae Hospital

Taeback Choongang General Hospital

Taegu Catholic University Hospital

Taegu Fatima Hospital

The Catholic University of Korea Kangnam St Marys Hospital

The Catholic University of Korea Taejon St Marys Hospital

The Catholic University of Korea Our Lady of mercy Hospital

The Catholic University of Korea St Vincents Hospital

Uijongbu St Marys Hospital The Catholic University of Korea

Ulsan University Hospital

Wallace Memorial Baptist Hospital

WonJu Christian Hospital Won Ju Clooege of Medicine Yonsei University

WonKwang University Hospital

Yeungnam University Medical Center

Yeungnam University Youngchun Hospital

Yonsei Medical center Yong-Dong Severance Hospital

Young Dong Hospital985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Appendix 2 Marginal frequency of malignant cases by sexgender and ICD-10 grouping in 2001985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114

Male FemaleSite (code) 985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103}}}}}985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

n n 985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Lip (C00) 17 00 11 00

Tongue (C01~02) 209 04 79 02

Mouth (C03~06) 242 05 99 02

Salivary glands (C07~08) 136 03 107 03

Tonsil (C09) 109 02 15 00

Other oropharynx (C10) 46 01 6 00

Nasopharynx (C11) 218 04 81 02

Hypopharynx (C12~13) 239 05 14 00

Pharynx unspecified (C14) 27 01 3 00

Oesophagus (C15) 1416 27 120 03

Stomach (C16) 12356 239 6050 151

Small intestine (C17) 204 04 140 03

Colon (C18) 2620 51 2112 53

Rectum (C19~20) 2814 54 2073 52

Anus (C21) 59 01 62 02

Liver (C22) 8259 160 2596 65

Gallbladder etc(C23~24) 1361 26 1241 31

Pancreas (C25) 1187 23 854 21

Nose sinuses etc(C30~31) 148 03 81 02

Larynx (C32) 920 18 71 02

TrecheaTrachea bronchus and lung (C33~34) 8292 160 2632 65

Other thoracic organs (C37~38) 157 03 89 02

Bone (C40~41) 218 04 191 05

Melanoma of skin (C43) 112 02 111 03

Other skin (C44) 509 10 493 12

Mesothelioma (C45) 27 01 11 00

Kaposi sarcoma (C46) 7 00 6 00

Connective and soft tissue (C47~49) 294 06 251 06

Breast (C50) 36 01 6459 161

Vulva (C51) - - 67 02

Vagina (C52) - - 48 01

Cervix uteri (C53) - - 4054 101

Corpus uteri (C54) - - 739 18

Uterus unspecified (C55) - - 61 02

Ovary (C56) - - 1520 38

Other female genital organs (C57) - - 34 01

Placenta (C58) 0 00 69 02

Penis (C60) 44 01 - -

Prostate (C61) 1466 28 - -

Testis (C62) 133 03 - -

Other male genital organs (C63) 28 01 - -

Kidney (C64) 1011 20 465 12

Renal pelvis (C65) 128 02 29 01

Ureter (C66) 117 02 62 02

Bladder (C67) 1730 33 415 10

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Hai-Rim Shin et alAnnual Report of the KCCR-2001 29

Appendix 2 Continued985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114

Male FemaleSite (code) 985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103}}}}}}}}}985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

n n 985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Other urinary organs (C68) 21 00 24 01

Eye (C69) 51 01 40 01

Brain nervous system (C70~72) 609 12 489 12

Thyroid (C73) 551 11 3305 82

Adrenal gland (C74) 71 01 48 01

Other endocrine (C75) 46 01 20 00

Hodgkin disease (C81) 92 02 42 01

Non-Hodgkin lymphoma (C82~85 C96) 1185 23 793 20

Immunoproliferative diseases (C88) 9 00 0 00

Multiple myeloma (C90) 267 05 202 05

Lymphoid leukaemia (C91) 290 06 194 05

Myeloid leukaemia (C92~94) 645 12 555 14

Leukaemia unspecified (C95) 39 01 39 01

Other and unspecified 981 19 819 20 (C26 C39 C48 C76 C80 C97)

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

30 Cancer Research and Treatment 200436(1)

Table 2 Frequency of major cancer cases by gender and age in 2001 Korea985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114

Male FemaleAge

Rank 985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103group

Site N () Site N ()985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

0~14 1 Hematopoietic 240 (363) Hematopoietic 162 (341)

2 Brain 105 (159) Brain 78 (164)

3 Adrenal gland 42 (64) Adrenal gland 25 (53)

4 Bone and Joints and articular 30 (45) Ovary 24 (51)

cartilage of limbs

5 Testis 29 (44) Bone and Joints and articular 21 (44)

cartilage of limbs

6 Lymph nodes 29 (44) Eye and adnexa 21 (44)

7 Connective subcutaneous and 28 (42) Thyroid gland 19 (40)

other soft tissues

8 Eye and adnexa 27 (41) Kidney 18 (38)

9 Kidney 24 (36) Connective subcutaneous 16 (34)

and other soft tissues

10 Liver and intrahepatic bile ducts 16 (24) Lymph nodes 16 (34)

etc 91 (138) 75 (158)985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Subtotal 675 731

98510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510315~34 1 Stomach 344 (179) Thyroid gland 780 (225)

2 Hematopoietic 266 (138) Breast 611 (176)

3 Liver and intrahepatic bile ducts 154 (80) Stomach 375 (108)

4 Colorectum 132 (69) Cervix uteri 342 (99)

5 Brain 130 (68) Ovary 309 (89)

6 Lymph nodes 123 (64) Hematopoietic 203 (59)

7 Thyroid gland 112 (58) Colorectum 125 (36)

8 Testis 68 (35) Brain 87 (25)

9 Bone and Joints and articular 63 (33) Lymph nodes 66 (19)

cartilage of limbs

10 Bronchus and lung 56 (29) Corpus uteri 53 (15)

etc 475 (247) 518 (149)

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103Subtotal 1836 3521

98510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510398510335~64 1 Stomach 7747 (261) Breast 5311 (221)

2 Liver and intrahepatic bile ducts 6073 (204) Stomach 3346 (139)

3 Bronchus and lung 3839 (129) Cervix uteri 2987 (124)

4 Colorectum 3265 (110) Colorectum 2188 (91)

5 Bladder 844 (28) Thyroid gland 2161 (90)

6 Esophagus 762 (26) Liver and intrahepatic bile ducts 1450 (60)

7 Kidney 697 (23) Bronchus and lung 1214 (50)

8 Pancreas 656 (22) Ovary 939 (39)

9 Hematopoietic 622 (21) Corpus uteri 565 (24)

10 Larynx 538 (18) Hematopoietic 461 (19)

etc 4695 (158) 3450 (143)985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Subtotal 30752 25994

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Hai-Rim Shin et alAnnual Report of the KCCR-2001 21

22 Cancer Research and Treatment 200436(1)

Table 3 Frequency of primary in-situ cases in 2001 Korea985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114

Male Female Rank 985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103}}}}}}}}985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Malignant in-situ (n=122) Malignant in-situ (n=3476)

Primary site 985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103 Primary site 985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103N () N () N () N ()

9851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851031 Skin 648 (969) 33 (18) Cervix 4061 (584) 2898 (416)

2 Bladder 1734 (992) 29 (31) Breast 6469 (932) 473 (68)

3 Colon 2657 (995) 25 (37) Skin 613 (958) 27 (42)

4 Stomach 12481 (999) 24 (08) Colon 2139 (994) 12 (06)

5 Larynx 923 (989) 20 (02) Vagina 49 (803) 12 (197)

etc 33310 (999) 64 (02) 26860 (998) 54 (02)985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Table 2 Continued 985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114

Male FemaleAge

Rank 985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103group

Site N () Site N ()985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

65+ 1 Stomach 4388 (226) Stomach 2442 (201)

2 Bronchus and lung 4385 (226) Colorectum 1903 (156)

3 Colorectum 2074 (107) Bronchus and lung 1372 (113)

4 Liver and intrahepatic 2018 (104) Liver and intrahepatic 1095 (90)

bile ducts bile ducts

5 Prostate gland 1079 (56) Cervix uteri 731 (60)

6 Bladder 857 (44) Breast 547 (45)

7 Esophagus 657 (34) Pancreas 510 (42)

8 Pancreas 517 (27) Thyroid gland 357 (29)

9 Other and unspecified 436 (22) Gallbladder 339 (28)

parts of biliary tract

10 Larynx 382 (20) Other and unspecified 323 (27)

parts of biliary tract

etc 2638 (136) 2556 (210)985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Subtotal 22135 13599

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

infiltrating duct carcinomas The most common site of colon cancer (C18) was the sigmoid colon (398 in males and 357 in females respectively) and the most frequent morpho-logic type was adenocarcinomas (600 in males and 601 in females) Only 112 of male and 111 of female rectal cancers occurred in the rectosigmoid junction As with other cancers adenocarcinomas were the major morphologic type of rectal cancer (625 in males and 606 in females) Appendix 2 shows the distribution of cancer cases by ICD-10 for easy comparison of the cancer death statistics

DISCUSSION

Information on the incidence and mortality of cancers and their changing trends is an essential component in the planning and monitoring of programs for cancer prevention early dete-ction and treatment (2) The Korea Central Cancer Registry (KCCR) was started as an ambitious project of the Ministry of Health and Welfare

Table 4 Frequency of topography and morphology in major cancer sites985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114

Male Female985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103}}}985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103Topography Cases () Morphology Cases () Topography Cases () Morphology Cases ()985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103Stomach (C16)985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103Gastric antrum 4258 Adenocarcinoma 6539 Gastric antrum 2015 Adenocarcinoma 3020

(341) (524) (327) (490)

Body 2900 Tubular adeno ca 3041 Body 1623 Signet ring cell ca 1315

(232) (244) (263) (213)

Overlapping 1698 Signet ring cell ca 1599 Overlapping 838 Tubular adeno ca 1079

lesion (136) (128) lesion (136) (175)

Cardia NOS 483 Mucinous adeno ca 187 Cardia NOS 170 Mucinous adeno ca 98

(39) (15) (28) (16)

Lesser curvature 394 Papillary adeno ca 95 Lesser curvature 164 Leiomyosarcoma 73

(32) (08) (27) (12)

2748 1020 1357 582

(220) (82) (220) (94)985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103Bronchus and lung (C34)985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103Upper lobe 2617 Squamous cell ca 3266 Upper lobe 693 Adenocarcinoma 1056

(316) (394) (263) (400)

Lower lobe 1773 Adenocarcinoma 1838 Lower lobe 592 Squamous cell ca 349

(214) (222) (224) (132)

Main bronchus 375 Small cell ca 1201 Middle lobe 137 Small cell ca 245

(45) (145) (52) (93)

Middle lobe 312 Bronchiolo-alveolar 68 Main bronchus 73 Bronchiolo-alveolar 104

(38) adeno ca (08) (28) adeno ca (39)

Overlapping lesion 241 Carcinoid tumor 59 Overlapping lesion 71 Acinar cell ca 41

(29) (07) (27) (16)

Lung NOS 2966 1852 Lung NOS 1072 843

(358) (224) (406) (320)985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103Liver and intrahepatic bile ducts (C22)985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103Liver 7062 Hepatocellular ca 6293 Liver 1905 Hepatocellular ca 1654

(855) (762) (734) (637)

Intrahepatic 1199 Cholangiocarcinoma 418 Intrahepatic 690 Cholangiocarcinoma 213

bile duct (145) (51) bile duct (266) (82)

Adenocarcinoma 173 Adenocarcinoma 92

(21) (35)

Combined hepatocellular 27 Hepatoblastoma 10

ca and cholangio ca (03) (04)

Tubular adeno ca 10 Combined hepatocellular 8

Hepatoblastoma (01) ca and cholangio ca (03)

Tubular adeno ca

1330 610

(161) (235)

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Hai-Rim Shin et alAnnual Report of the KCCR-2001 23

24 Cancer Research and Treatment 200436(1)

Table 4 Continued 985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114

Male Female985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103}}}985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103Topography Cases () Morphology Cases () Topography Cases () Morphology Cases ()

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103Breast (C50)985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Upper outer 2300 Infiltrating duct ca 5346

(356) (826)

Overlapping 839 Lobular ca 221

lesion (130) (34)

Upper inner 752 Mucinous adeno ca 144

(116) (22)

Lower outer 371 Medullary ca 116

(57) (18)

Central portion 329 Papillary ca 80

(51) (12)

1878 562

(290) (87)985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103Rectum (C19-C20)985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103Rectum NOS 2501 Adenocarcinoma 1762 Rectum NOS 1850 Adenocarcinoma 1261

(888) (625) (889) (606)

Rectosigmoid 316 Tubular adeno ca 677 Rectosigmoid 232 Tubular adeno ca 478

junction (112) (240) junction (111) (230)

Mucinous adeno ca 73 Mucinous adeno ca 66

(26) (32)

Carcinoid tumor 48 Papillary adeno ca 48

(17) (23)

Papillary adeno ca 48 Carcinoid tumor 28

(17) (13)

209 201

(74) (97)985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103Colon (C18)985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103}Sigmoid colon 1057 Adenocarcinoma 1593 Sigmoid colon 763 Adenocarcinoma 1286

(600) (357) (398) (601)

Ascending colon 494 Tubular adeno ca 559 Ascending colon 517 Tubular adeno ca 431

(186) (210) (242) (201)

Transverse colon 206 Mucinous adeno ca 163 Transverse colon 162 Mucinous adeno ca 149

(78) (61) (76) (70)

Descending colon 152 Papillary adeno ca 67 Cecum 136 Papillary adeno ca 40

(57) (25) (64) (19)

Cecum 126 Malig Lymphoma 26 Descending colon 101 Malig Lymphoma 15

(47) large cell diffuse (10) (47) large cell diffuse (07)

622 249 460 218

(234) (94) (215) (102)

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Hai-Rim Shin et alAnnual Report of the KCCR-2001 25

in 1980 In the beginning 47 nationwide resident-training general hospitals participated in this program The number of participating hospitals and registered malignancies has incre-ased year-by-year with 134 hospitals submitting their data diskettes in 2001 (1) The number of cancer cases in the KCCR for 2000 was assumed to be more than 90 precise for cancer cases with the comparison of the estimated cancer incidence cases (3) using national mortality data and the incidence data from four frontier regional cancer registries including Kangwha Seoul Busan and Daegu in the Cancer Incidence in Five Continents (4) The KCCR database is especially useful for showing the trend of cancer occurrence in Korea as information on the changing trend of cancer incidence over time is an essential component in the planning and monitoring of programs for cancer prevention early detection and treatment Major cancers including stomach lung liver breast and colorectum but with the exception of uterine cervix cancer were increasing (data not shown) For uterine cervix cancer the proportion of carcinoma in-situ cases increased among the registered cases meaning significant uterine cervix cancers were detected at an early stage Currently KCCR being a nationwide hospital-based cancer registry is supporting technically and financially 9 population- based regional registries Seoul Busan Daegu Incheon Gwangju Daejeon Ulsan Jejudo and Goyang-si in 2003 The KCCR database continues to hold the most important position until a nationwide population-based data acquisition program can be constructed on the basis of international standards One area for caution in the interpretation of the KCCR data

is that the numbers outlined in this report do not represent persons but cases that have been reported The patients who had cancers at several sites have been treated as multiple primary patients and have been reported according to the cancer site

ACKNOWLEDGEMENTS

We would like to sincerely thank the participation of the medical record administrators in the KCCR-affiliated hospitals [Appendix 1] who enthusiastically participated in the KCCR by registering new cancer cases We would also like to thank Ji-Young Kim MRA Su-Jin Kim MS Hye-Jin Kim MRA Kwang-Suk Park MRA and Ji-Young Oh MRA for their devoted efforts to mining and clearing the KCCR data set

REFERENCES

1 Ministry Health and Welfare 2001 Annual report of Korea Central Cancer Registry (published in 2003) Available from URLhttpwwwnccrekr

2 WHO IARC Cancer Registration Principles and methods 1991 Lyon France

3 Shin HR Ahn YO Bae JM Shin MH Lee DH Lee CW Ohrr HC Ahn DH Ferlay J Parkin DM Oh DK Park JG Cancer Incidence in Korea Cancer Research and Treatment 2002 405-408

4 WHO IARC Cancer Incidence in Five Continents Volume VIII 2002

Appendix 1 List of the Hospitals participating in the 2001 KCCR program985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114

Ajou University Hospital

Andong General Hospital

Andong Presbyterian Hospital

Ansan Hando General Hospital

Asan Medical Center

Bag Ae Hospital

Benedict Hospital

Bupyeong Serim Hospital

Busan Veterans Hospital

Carollo Hospital

Catholic GEN Hospital

Changwon Fatima Hospital

Changwon General Hospital

ChonBuk National University Hospital

Chongju St Marys Hospital

Chonnam University Hospital

Choon Hae Hospital

Chosun University Hospital

Chung-Ang University Hospital

ChungAng University Medical Center

Chungbuk National University Hospital

Chungnam National University Hospital

College of Medicine Pochon CHA university CHA General Hospital

Dae Dong hospital

Dae Jeon Veterans Hospital

Dae Rim St Marys Hospital

Daegu Medical Center

Daewoo Hospital

DanKook University Hospital

Dong Kang General Hospital

Dong Rae Bong Seng Hospital

Dong-A University Hospital

Dongeui Medical Center

Dongguk University Kyong Ju Hospital

Dong-In Hospital

Dong-Kuk University Po-Hang Hospital

Dongsan Medical Center

Ewha Womans University Mokdong Hospital

Ewha Womans University Tongdaemun Hospital

Gachon Medical School Gil Medical Center

Gangneung Asan Hospital

Gangneung Medical Center

Gyeongsang University Hospital

Hae Dong Hospital

Halla General hospital

Hallym Sacred Heart Hospital

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

26 Cancer Research and Treatment 200436(1)

Appendix 1 Continued

985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114Hallym University Hang Gang Sacred Heart Hospital

Hallym University Medical Center ChunCheon Sacred Heart Hospital

Hangdong University Sunlin Presbyterian Hospital

Hanil Hospital

Hanyang University Hospital

Hanyang University Kuri Hospital

Holy Hamily Hospital

Il Sin Christian Hospital

In Je University Pusan Paik hospital

Inchon Christian Hospital

Inha University Hospital

Inha University Medical Center Inha Hospital

Inje Univ Ilsan Paik Hospital

Inje University Sanggye Paik Hospital

Inje University Seoul Paik Hospital

kang Dong Sacred Heart Hospital

Kangbuk Samsung Hospital

kangnam General Hospital Public Corporation

KangNam Sacred Heart Hospital Hallym University

Keimyung University Medical Center

Kon Kuk University Medical Center Seoul Hospital

Konyang University Hospital

Korea Cancer Center Hospital

Korea University Ansan Hospital

Korea University College of Medicine Guro Hospital

Korea University Hospital

Korea Veterans Hospital

Kosin University Gospel Hospital

Kwaks Hospital

Kwang Ju Christian Hospital

Kwang Ju Veterans Hospital

Kwang Myung Sung Ae General Hospital

Kwanghye General Hospital

Kyung Hee Medical Center

Kyungpook National University Hospital

Local Public Corp Inchun Medical Center

Local Public Corporation Chung Cheong Nam-do Hong Sung Medical Center

Maryknoll General Hospital

Masan Samsung Hospital

Mokpo Catholic Hospital

Moonhwa Hospital

Nam Kwang Hospital

National Cancer Center

National Health Insurance Corporation Ilsan Hospital

National Medical Center

National Police Hospital

Pochon Cha Univ Kumicha medical center

Pohang St Marys Hospital

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Hai-Rim Shin et alAnnual Report of the KCCR-2001 27

28 Cancer Research and Treatment 200436(1)

Appendix 1 Continued

985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114Presbyterian Medical Center

Pundang Je-Saeng Hospital

Pusan Adventist Hospital

Pusan Medical Center

Pusan National University Hospital

Samsun Hospital

Samsung Medical center

Sansung Cheil Hospital amp Womens Health Care Center

Sejong General Hospital

Seo San Medical Center

Seoul Adventist Hospital

Seoul Municipal Boramae Hospital

Seoul National University Hospital

Seoul Red Cross Hospital

Severance Hospital Yonsei University Medical College

Shin Chun Hospital

Soonchunhyang GuMi Hospital

Soonchunhyang University Cheonan Hospital

Soonchunyang Univ Hospital

St Marys hospital The Catholic University of Korea

St Francisco General Hospital

St Pauls Hospital

Sun General Hospital

Sung Ae Hospital

Taeback Choongang General Hospital

Taegu Catholic University Hospital

Taegu Fatima Hospital

The Catholic University of Korea Kangnam St Marys Hospital

The Catholic University of Korea Taejon St Marys Hospital

The Catholic University of Korea Our Lady of mercy Hospital

The Catholic University of Korea St Vincents Hospital

Uijongbu St Marys Hospital The Catholic University of Korea

Ulsan University Hospital

Wallace Memorial Baptist Hospital

WonJu Christian Hospital Won Ju Clooege of Medicine Yonsei University

WonKwang University Hospital

Yeungnam University Medical Center

Yeungnam University Youngchun Hospital

Yonsei Medical center Yong-Dong Severance Hospital

Young Dong Hospital985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Appendix 2 Marginal frequency of malignant cases by sexgender and ICD-10 grouping in 2001985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114

Male FemaleSite (code) 985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103}}}}}985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

n n 985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Lip (C00) 17 00 11 00

Tongue (C01~02) 209 04 79 02

Mouth (C03~06) 242 05 99 02

Salivary glands (C07~08) 136 03 107 03

Tonsil (C09) 109 02 15 00

Other oropharynx (C10) 46 01 6 00

Nasopharynx (C11) 218 04 81 02

Hypopharynx (C12~13) 239 05 14 00

Pharynx unspecified (C14) 27 01 3 00

Oesophagus (C15) 1416 27 120 03

Stomach (C16) 12356 239 6050 151

Small intestine (C17) 204 04 140 03

Colon (C18) 2620 51 2112 53

Rectum (C19~20) 2814 54 2073 52

Anus (C21) 59 01 62 02

Liver (C22) 8259 160 2596 65

Gallbladder etc(C23~24) 1361 26 1241 31

Pancreas (C25) 1187 23 854 21

Nose sinuses etc(C30~31) 148 03 81 02

Larynx (C32) 920 18 71 02

TrecheaTrachea bronchus and lung (C33~34) 8292 160 2632 65

Other thoracic organs (C37~38) 157 03 89 02

Bone (C40~41) 218 04 191 05

Melanoma of skin (C43) 112 02 111 03

Other skin (C44) 509 10 493 12

Mesothelioma (C45) 27 01 11 00

Kaposi sarcoma (C46) 7 00 6 00

Connective and soft tissue (C47~49) 294 06 251 06

Breast (C50) 36 01 6459 161

Vulva (C51) - - 67 02

Vagina (C52) - - 48 01

Cervix uteri (C53) - - 4054 101

Corpus uteri (C54) - - 739 18

Uterus unspecified (C55) - - 61 02

Ovary (C56) - - 1520 38

Other female genital organs (C57) - - 34 01

Placenta (C58) 0 00 69 02

Penis (C60) 44 01 - -

Prostate (C61) 1466 28 - -

Testis (C62) 133 03 - -

Other male genital organs (C63) 28 01 - -

Kidney (C64) 1011 20 465 12

Renal pelvis (C65) 128 02 29 01

Ureter (C66) 117 02 62 02

Bladder (C67) 1730 33 415 10

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Hai-Rim Shin et alAnnual Report of the KCCR-2001 29

Appendix 2 Continued985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114

Male FemaleSite (code) 985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103}}}}}}}}}985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

n n 985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Other urinary organs (C68) 21 00 24 01

Eye (C69) 51 01 40 01

Brain nervous system (C70~72) 609 12 489 12

Thyroid (C73) 551 11 3305 82

Adrenal gland (C74) 71 01 48 01

Other endocrine (C75) 46 01 20 00

Hodgkin disease (C81) 92 02 42 01

Non-Hodgkin lymphoma (C82~85 C96) 1185 23 793 20

Immunoproliferative diseases (C88) 9 00 0 00

Multiple myeloma (C90) 267 05 202 05

Lymphoid leukaemia (C91) 290 06 194 05

Myeloid leukaemia (C92~94) 645 12 555 14

Leukaemia unspecified (C95) 39 01 39 01

Other and unspecified 981 19 819 20 (C26 C39 C48 C76 C80 C97)

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

30 Cancer Research and Treatment 200436(1)

22 Cancer Research and Treatment 200436(1)

Table 3 Frequency of primary in-situ cases in 2001 Korea985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114

Male Female Rank 985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103}}}}}}}}985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Malignant in-situ (n=122) Malignant in-situ (n=3476)

Primary site 985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103 Primary site 985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103N () N () N () N ()

9851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851039851031 Skin 648 (969) 33 (18) Cervix 4061 (584) 2898 (416)

2 Bladder 1734 (992) 29 (31) Breast 6469 (932) 473 (68)

3 Colon 2657 (995) 25 (37) Skin 613 (958) 27 (42)

4 Stomach 12481 (999) 24 (08) Colon 2139 (994) 12 (06)

5 Larynx 923 (989) 20 (02) Vagina 49 (803) 12 (197)

etc 33310 (999) 64 (02) 26860 (998) 54 (02)985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Table 2 Continued 985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114

Male FemaleAge

Rank 985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103group

Site N () Site N ()985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

65+ 1 Stomach 4388 (226) Stomach 2442 (201)

2 Bronchus and lung 4385 (226) Colorectum 1903 (156)

3 Colorectum 2074 (107) Bronchus and lung 1372 (113)

4 Liver and intrahepatic 2018 (104) Liver and intrahepatic 1095 (90)

bile ducts bile ducts

5 Prostate gland 1079 (56) Cervix uteri 731 (60)

6 Bladder 857 (44) Breast 547 (45)

7 Esophagus 657 (34) Pancreas 510 (42)

8 Pancreas 517 (27) Thyroid gland 357 (29)

9 Other and unspecified 436 (22) Gallbladder 339 (28)

parts of biliary tract

10 Larynx 382 (20) Other and unspecified 323 (27)

parts of biliary tract

etc 2638 (136) 2556 (210)985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Subtotal 22135 13599

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

infiltrating duct carcinomas The most common site of colon cancer (C18) was the sigmoid colon (398 in males and 357 in females respectively) and the most frequent morpho-logic type was adenocarcinomas (600 in males and 601 in females) Only 112 of male and 111 of female rectal cancers occurred in the rectosigmoid junction As with other cancers adenocarcinomas were the major morphologic type of rectal cancer (625 in males and 606 in females) Appendix 2 shows the distribution of cancer cases by ICD-10 for easy comparison of the cancer death statistics

DISCUSSION

Information on the incidence and mortality of cancers and their changing trends is an essential component in the planning and monitoring of programs for cancer prevention early dete-ction and treatment (2) The Korea Central Cancer Registry (KCCR) was started as an ambitious project of the Ministry of Health and Welfare

Table 4 Frequency of topography and morphology in major cancer sites985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114

Male Female985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103}}}985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103Topography Cases () Morphology Cases () Topography Cases () Morphology Cases ()985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103Stomach (C16)985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103Gastric antrum 4258 Adenocarcinoma 6539 Gastric antrum 2015 Adenocarcinoma 3020

(341) (524) (327) (490)

Body 2900 Tubular adeno ca 3041 Body 1623 Signet ring cell ca 1315

(232) (244) (263) (213)

Overlapping 1698 Signet ring cell ca 1599 Overlapping 838 Tubular adeno ca 1079

lesion (136) (128) lesion (136) (175)

Cardia NOS 483 Mucinous adeno ca 187 Cardia NOS 170 Mucinous adeno ca 98

(39) (15) (28) (16)

Lesser curvature 394 Papillary adeno ca 95 Lesser curvature 164 Leiomyosarcoma 73

(32) (08) (27) (12)

2748 1020 1357 582

(220) (82) (220) (94)985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103Bronchus and lung (C34)985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103Upper lobe 2617 Squamous cell ca 3266 Upper lobe 693 Adenocarcinoma 1056

(316) (394) (263) (400)

Lower lobe 1773 Adenocarcinoma 1838 Lower lobe 592 Squamous cell ca 349

(214) (222) (224) (132)

Main bronchus 375 Small cell ca 1201 Middle lobe 137 Small cell ca 245

(45) (145) (52) (93)

Middle lobe 312 Bronchiolo-alveolar 68 Main bronchus 73 Bronchiolo-alveolar 104

(38) adeno ca (08) (28) adeno ca (39)

Overlapping lesion 241 Carcinoid tumor 59 Overlapping lesion 71 Acinar cell ca 41

(29) (07) (27) (16)

Lung NOS 2966 1852 Lung NOS 1072 843

(358) (224) (406) (320)985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103Liver and intrahepatic bile ducts (C22)985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103Liver 7062 Hepatocellular ca 6293 Liver 1905 Hepatocellular ca 1654

(855) (762) (734) (637)

Intrahepatic 1199 Cholangiocarcinoma 418 Intrahepatic 690 Cholangiocarcinoma 213

bile duct (145) (51) bile duct (266) (82)

Adenocarcinoma 173 Adenocarcinoma 92

(21) (35)

Combined hepatocellular 27 Hepatoblastoma 10

ca and cholangio ca (03) (04)

Tubular adeno ca 10 Combined hepatocellular 8

Hepatoblastoma (01) ca and cholangio ca (03)

Tubular adeno ca

1330 610

(161) (235)

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Hai-Rim Shin et alAnnual Report of the KCCR-2001 23

24 Cancer Research and Treatment 200436(1)

Table 4 Continued 985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114

Male Female985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103}}}985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103Topography Cases () Morphology Cases () Topography Cases () Morphology Cases ()

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103Breast (C50)985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Upper outer 2300 Infiltrating duct ca 5346

(356) (826)

Overlapping 839 Lobular ca 221

lesion (130) (34)

Upper inner 752 Mucinous adeno ca 144

(116) (22)

Lower outer 371 Medullary ca 116

(57) (18)

Central portion 329 Papillary ca 80

(51) (12)

1878 562

(290) (87)985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103Rectum (C19-C20)985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103Rectum NOS 2501 Adenocarcinoma 1762 Rectum NOS 1850 Adenocarcinoma 1261

(888) (625) (889) (606)

Rectosigmoid 316 Tubular adeno ca 677 Rectosigmoid 232 Tubular adeno ca 478

junction (112) (240) junction (111) (230)

Mucinous adeno ca 73 Mucinous adeno ca 66

(26) (32)

Carcinoid tumor 48 Papillary adeno ca 48

(17) (23)

Papillary adeno ca 48 Carcinoid tumor 28

(17) (13)

209 201

(74) (97)985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103Colon (C18)985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103}Sigmoid colon 1057 Adenocarcinoma 1593 Sigmoid colon 763 Adenocarcinoma 1286

(600) (357) (398) (601)

Ascending colon 494 Tubular adeno ca 559 Ascending colon 517 Tubular adeno ca 431

(186) (210) (242) (201)

Transverse colon 206 Mucinous adeno ca 163 Transverse colon 162 Mucinous adeno ca 149

(78) (61) (76) (70)

Descending colon 152 Papillary adeno ca 67 Cecum 136 Papillary adeno ca 40

(57) (25) (64) (19)

Cecum 126 Malig Lymphoma 26 Descending colon 101 Malig Lymphoma 15

(47) large cell diffuse (10) (47) large cell diffuse (07)

622 249 460 218

(234) (94) (215) (102)

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Hai-Rim Shin et alAnnual Report of the KCCR-2001 25

in 1980 In the beginning 47 nationwide resident-training general hospitals participated in this program The number of participating hospitals and registered malignancies has incre-ased year-by-year with 134 hospitals submitting their data diskettes in 2001 (1) The number of cancer cases in the KCCR for 2000 was assumed to be more than 90 precise for cancer cases with the comparison of the estimated cancer incidence cases (3) using national mortality data and the incidence data from four frontier regional cancer registries including Kangwha Seoul Busan and Daegu in the Cancer Incidence in Five Continents (4) The KCCR database is especially useful for showing the trend of cancer occurrence in Korea as information on the changing trend of cancer incidence over time is an essential component in the planning and monitoring of programs for cancer prevention early detection and treatment Major cancers including stomach lung liver breast and colorectum but with the exception of uterine cervix cancer were increasing (data not shown) For uterine cervix cancer the proportion of carcinoma in-situ cases increased among the registered cases meaning significant uterine cervix cancers were detected at an early stage Currently KCCR being a nationwide hospital-based cancer registry is supporting technically and financially 9 population- based regional registries Seoul Busan Daegu Incheon Gwangju Daejeon Ulsan Jejudo and Goyang-si in 2003 The KCCR database continues to hold the most important position until a nationwide population-based data acquisition program can be constructed on the basis of international standards One area for caution in the interpretation of the KCCR data

is that the numbers outlined in this report do not represent persons but cases that have been reported The patients who had cancers at several sites have been treated as multiple primary patients and have been reported according to the cancer site

ACKNOWLEDGEMENTS

We would like to sincerely thank the participation of the medical record administrators in the KCCR-affiliated hospitals [Appendix 1] who enthusiastically participated in the KCCR by registering new cancer cases We would also like to thank Ji-Young Kim MRA Su-Jin Kim MS Hye-Jin Kim MRA Kwang-Suk Park MRA and Ji-Young Oh MRA for their devoted efforts to mining and clearing the KCCR data set

REFERENCES

1 Ministry Health and Welfare 2001 Annual report of Korea Central Cancer Registry (published in 2003) Available from URLhttpwwwnccrekr

2 WHO IARC Cancer Registration Principles and methods 1991 Lyon France

3 Shin HR Ahn YO Bae JM Shin MH Lee DH Lee CW Ohrr HC Ahn DH Ferlay J Parkin DM Oh DK Park JG Cancer Incidence in Korea Cancer Research and Treatment 2002 405-408

4 WHO IARC Cancer Incidence in Five Continents Volume VIII 2002

Appendix 1 List of the Hospitals participating in the 2001 KCCR program985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114

Ajou University Hospital

Andong General Hospital

Andong Presbyterian Hospital

Ansan Hando General Hospital

Asan Medical Center

Bag Ae Hospital

Benedict Hospital

Bupyeong Serim Hospital

Busan Veterans Hospital

Carollo Hospital

Catholic GEN Hospital

Changwon Fatima Hospital

Changwon General Hospital

ChonBuk National University Hospital

Chongju St Marys Hospital

Chonnam University Hospital

Choon Hae Hospital

Chosun University Hospital

Chung-Ang University Hospital

ChungAng University Medical Center

Chungbuk National University Hospital

Chungnam National University Hospital

College of Medicine Pochon CHA university CHA General Hospital

Dae Dong hospital

Dae Jeon Veterans Hospital

Dae Rim St Marys Hospital

Daegu Medical Center

Daewoo Hospital

DanKook University Hospital

Dong Kang General Hospital

Dong Rae Bong Seng Hospital

Dong-A University Hospital

Dongeui Medical Center

Dongguk University Kyong Ju Hospital

Dong-In Hospital

Dong-Kuk University Po-Hang Hospital

Dongsan Medical Center

Ewha Womans University Mokdong Hospital

Ewha Womans University Tongdaemun Hospital

Gachon Medical School Gil Medical Center

Gangneung Asan Hospital

Gangneung Medical Center

Gyeongsang University Hospital

Hae Dong Hospital

Halla General hospital

Hallym Sacred Heart Hospital

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

26 Cancer Research and Treatment 200436(1)

Appendix 1 Continued

985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114Hallym University Hang Gang Sacred Heart Hospital

Hallym University Medical Center ChunCheon Sacred Heart Hospital

Hangdong University Sunlin Presbyterian Hospital

Hanil Hospital

Hanyang University Hospital

Hanyang University Kuri Hospital

Holy Hamily Hospital

Il Sin Christian Hospital

In Je University Pusan Paik hospital

Inchon Christian Hospital

Inha University Hospital

Inha University Medical Center Inha Hospital

Inje Univ Ilsan Paik Hospital

Inje University Sanggye Paik Hospital

Inje University Seoul Paik Hospital

kang Dong Sacred Heart Hospital

Kangbuk Samsung Hospital

kangnam General Hospital Public Corporation

KangNam Sacred Heart Hospital Hallym University

Keimyung University Medical Center

Kon Kuk University Medical Center Seoul Hospital

Konyang University Hospital

Korea Cancer Center Hospital

Korea University Ansan Hospital

Korea University College of Medicine Guro Hospital

Korea University Hospital

Korea Veterans Hospital

Kosin University Gospel Hospital

Kwaks Hospital

Kwang Ju Christian Hospital

Kwang Ju Veterans Hospital

Kwang Myung Sung Ae General Hospital

Kwanghye General Hospital

Kyung Hee Medical Center

Kyungpook National University Hospital

Local Public Corp Inchun Medical Center

Local Public Corporation Chung Cheong Nam-do Hong Sung Medical Center

Maryknoll General Hospital

Masan Samsung Hospital

Mokpo Catholic Hospital

Moonhwa Hospital

Nam Kwang Hospital

National Cancer Center

National Health Insurance Corporation Ilsan Hospital

National Medical Center

National Police Hospital

Pochon Cha Univ Kumicha medical center

Pohang St Marys Hospital

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Hai-Rim Shin et alAnnual Report of the KCCR-2001 27

28 Cancer Research and Treatment 200436(1)

Appendix 1 Continued

985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114Presbyterian Medical Center

Pundang Je-Saeng Hospital

Pusan Adventist Hospital

Pusan Medical Center

Pusan National University Hospital

Samsun Hospital

Samsung Medical center

Sansung Cheil Hospital amp Womens Health Care Center

Sejong General Hospital

Seo San Medical Center

Seoul Adventist Hospital

Seoul Municipal Boramae Hospital

Seoul National University Hospital

Seoul Red Cross Hospital

Severance Hospital Yonsei University Medical College

Shin Chun Hospital

Soonchunhyang GuMi Hospital

Soonchunhyang University Cheonan Hospital

Soonchunyang Univ Hospital

St Marys hospital The Catholic University of Korea

St Francisco General Hospital

St Pauls Hospital

Sun General Hospital

Sung Ae Hospital

Taeback Choongang General Hospital

Taegu Catholic University Hospital

Taegu Fatima Hospital

The Catholic University of Korea Kangnam St Marys Hospital

The Catholic University of Korea Taejon St Marys Hospital

The Catholic University of Korea Our Lady of mercy Hospital

The Catholic University of Korea St Vincents Hospital

Uijongbu St Marys Hospital The Catholic University of Korea

Ulsan University Hospital

Wallace Memorial Baptist Hospital

WonJu Christian Hospital Won Ju Clooege of Medicine Yonsei University

WonKwang University Hospital

Yeungnam University Medical Center

Yeungnam University Youngchun Hospital

Yonsei Medical center Yong-Dong Severance Hospital

Young Dong Hospital985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Appendix 2 Marginal frequency of malignant cases by sexgender and ICD-10 grouping in 2001985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114

Male FemaleSite (code) 985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103}}}}}985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

n n 985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Lip (C00) 17 00 11 00

Tongue (C01~02) 209 04 79 02

Mouth (C03~06) 242 05 99 02

Salivary glands (C07~08) 136 03 107 03

Tonsil (C09) 109 02 15 00

Other oropharynx (C10) 46 01 6 00

Nasopharynx (C11) 218 04 81 02

Hypopharynx (C12~13) 239 05 14 00

Pharynx unspecified (C14) 27 01 3 00

Oesophagus (C15) 1416 27 120 03

Stomach (C16) 12356 239 6050 151

Small intestine (C17) 204 04 140 03

Colon (C18) 2620 51 2112 53

Rectum (C19~20) 2814 54 2073 52

Anus (C21) 59 01 62 02

Liver (C22) 8259 160 2596 65

Gallbladder etc(C23~24) 1361 26 1241 31

Pancreas (C25) 1187 23 854 21

Nose sinuses etc(C30~31) 148 03 81 02

Larynx (C32) 920 18 71 02

TrecheaTrachea bronchus and lung (C33~34) 8292 160 2632 65

Other thoracic organs (C37~38) 157 03 89 02

Bone (C40~41) 218 04 191 05

Melanoma of skin (C43) 112 02 111 03

Other skin (C44) 509 10 493 12

Mesothelioma (C45) 27 01 11 00

Kaposi sarcoma (C46) 7 00 6 00

Connective and soft tissue (C47~49) 294 06 251 06

Breast (C50) 36 01 6459 161

Vulva (C51) - - 67 02

Vagina (C52) - - 48 01

Cervix uteri (C53) - - 4054 101

Corpus uteri (C54) - - 739 18

Uterus unspecified (C55) - - 61 02

Ovary (C56) - - 1520 38

Other female genital organs (C57) - - 34 01

Placenta (C58) 0 00 69 02

Penis (C60) 44 01 - -

Prostate (C61) 1466 28 - -

Testis (C62) 133 03 - -

Other male genital organs (C63) 28 01 - -

Kidney (C64) 1011 20 465 12

Renal pelvis (C65) 128 02 29 01

Ureter (C66) 117 02 62 02

Bladder (C67) 1730 33 415 10

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Hai-Rim Shin et alAnnual Report of the KCCR-2001 29

Appendix 2 Continued985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114

Male FemaleSite (code) 985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103}}}}}}}}}985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

n n 985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Other urinary organs (C68) 21 00 24 01

Eye (C69) 51 01 40 01

Brain nervous system (C70~72) 609 12 489 12

Thyroid (C73) 551 11 3305 82

Adrenal gland (C74) 71 01 48 01

Other endocrine (C75) 46 01 20 00

Hodgkin disease (C81) 92 02 42 01

Non-Hodgkin lymphoma (C82~85 C96) 1185 23 793 20

Immunoproliferative diseases (C88) 9 00 0 00

Multiple myeloma (C90) 267 05 202 05

Lymphoid leukaemia (C91) 290 06 194 05

Myeloid leukaemia (C92~94) 645 12 555 14

Leukaemia unspecified (C95) 39 01 39 01

Other and unspecified 981 19 819 20 (C26 C39 C48 C76 C80 C97)

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

30 Cancer Research and Treatment 200436(1)

Table 4 Frequency of topography and morphology in major cancer sites985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114

Male Female985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103}}}985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103Topography Cases () Morphology Cases () Topography Cases () Morphology Cases ()985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103Stomach (C16)985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103Gastric antrum 4258 Adenocarcinoma 6539 Gastric antrum 2015 Adenocarcinoma 3020

(341) (524) (327) (490)

Body 2900 Tubular adeno ca 3041 Body 1623 Signet ring cell ca 1315

(232) (244) (263) (213)

Overlapping 1698 Signet ring cell ca 1599 Overlapping 838 Tubular adeno ca 1079

lesion (136) (128) lesion (136) (175)

Cardia NOS 483 Mucinous adeno ca 187 Cardia NOS 170 Mucinous adeno ca 98

(39) (15) (28) (16)

Lesser curvature 394 Papillary adeno ca 95 Lesser curvature 164 Leiomyosarcoma 73

(32) (08) (27) (12)

2748 1020 1357 582

(220) (82) (220) (94)985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103Bronchus and lung (C34)985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103Upper lobe 2617 Squamous cell ca 3266 Upper lobe 693 Adenocarcinoma 1056

(316) (394) (263) (400)

Lower lobe 1773 Adenocarcinoma 1838 Lower lobe 592 Squamous cell ca 349

(214) (222) (224) (132)

Main bronchus 375 Small cell ca 1201 Middle lobe 137 Small cell ca 245

(45) (145) (52) (93)

Middle lobe 312 Bronchiolo-alveolar 68 Main bronchus 73 Bronchiolo-alveolar 104

(38) adeno ca (08) (28) adeno ca (39)

Overlapping lesion 241 Carcinoid tumor 59 Overlapping lesion 71 Acinar cell ca 41

(29) (07) (27) (16)

Lung NOS 2966 1852 Lung NOS 1072 843

(358) (224) (406) (320)985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103Liver and intrahepatic bile ducts (C22)985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103Liver 7062 Hepatocellular ca 6293 Liver 1905 Hepatocellular ca 1654

(855) (762) (734) (637)

Intrahepatic 1199 Cholangiocarcinoma 418 Intrahepatic 690 Cholangiocarcinoma 213

bile duct (145) (51) bile duct (266) (82)

Adenocarcinoma 173 Adenocarcinoma 92

(21) (35)

Combined hepatocellular 27 Hepatoblastoma 10

ca and cholangio ca (03) (04)

Tubular adeno ca 10 Combined hepatocellular 8

Hepatoblastoma (01) ca and cholangio ca (03)

Tubular adeno ca

1330 610

(161) (235)

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Hai-Rim Shin et alAnnual Report of the KCCR-2001 23

24 Cancer Research and Treatment 200436(1)

Table 4 Continued 985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114

Male Female985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103}}}985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103Topography Cases () Morphology Cases () Topography Cases () Morphology Cases ()

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103Breast (C50)985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Upper outer 2300 Infiltrating duct ca 5346

(356) (826)

Overlapping 839 Lobular ca 221

lesion (130) (34)

Upper inner 752 Mucinous adeno ca 144

(116) (22)

Lower outer 371 Medullary ca 116

(57) (18)

Central portion 329 Papillary ca 80

(51) (12)

1878 562

(290) (87)985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103Rectum (C19-C20)985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103Rectum NOS 2501 Adenocarcinoma 1762 Rectum NOS 1850 Adenocarcinoma 1261

(888) (625) (889) (606)

Rectosigmoid 316 Tubular adeno ca 677 Rectosigmoid 232 Tubular adeno ca 478

junction (112) (240) junction (111) (230)

Mucinous adeno ca 73 Mucinous adeno ca 66

(26) (32)

Carcinoid tumor 48 Papillary adeno ca 48

(17) (23)

Papillary adeno ca 48 Carcinoid tumor 28

(17) (13)

209 201

(74) (97)985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103Colon (C18)985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103}Sigmoid colon 1057 Adenocarcinoma 1593 Sigmoid colon 763 Adenocarcinoma 1286

(600) (357) (398) (601)

Ascending colon 494 Tubular adeno ca 559 Ascending colon 517 Tubular adeno ca 431

(186) (210) (242) (201)

Transverse colon 206 Mucinous adeno ca 163 Transverse colon 162 Mucinous adeno ca 149

(78) (61) (76) (70)

Descending colon 152 Papillary adeno ca 67 Cecum 136 Papillary adeno ca 40

(57) (25) (64) (19)

Cecum 126 Malig Lymphoma 26 Descending colon 101 Malig Lymphoma 15

(47) large cell diffuse (10) (47) large cell diffuse (07)

622 249 460 218

(234) (94) (215) (102)

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Hai-Rim Shin et alAnnual Report of the KCCR-2001 25

in 1980 In the beginning 47 nationwide resident-training general hospitals participated in this program The number of participating hospitals and registered malignancies has incre-ased year-by-year with 134 hospitals submitting their data diskettes in 2001 (1) The number of cancer cases in the KCCR for 2000 was assumed to be more than 90 precise for cancer cases with the comparison of the estimated cancer incidence cases (3) using national mortality data and the incidence data from four frontier regional cancer registries including Kangwha Seoul Busan and Daegu in the Cancer Incidence in Five Continents (4) The KCCR database is especially useful for showing the trend of cancer occurrence in Korea as information on the changing trend of cancer incidence over time is an essential component in the planning and monitoring of programs for cancer prevention early detection and treatment Major cancers including stomach lung liver breast and colorectum but with the exception of uterine cervix cancer were increasing (data not shown) For uterine cervix cancer the proportion of carcinoma in-situ cases increased among the registered cases meaning significant uterine cervix cancers were detected at an early stage Currently KCCR being a nationwide hospital-based cancer registry is supporting technically and financially 9 population- based regional registries Seoul Busan Daegu Incheon Gwangju Daejeon Ulsan Jejudo and Goyang-si in 2003 The KCCR database continues to hold the most important position until a nationwide population-based data acquisition program can be constructed on the basis of international standards One area for caution in the interpretation of the KCCR data

is that the numbers outlined in this report do not represent persons but cases that have been reported The patients who had cancers at several sites have been treated as multiple primary patients and have been reported according to the cancer site

ACKNOWLEDGEMENTS

We would like to sincerely thank the participation of the medical record administrators in the KCCR-affiliated hospitals [Appendix 1] who enthusiastically participated in the KCCR by registering new cancer cases We would also like to thank Ji-Young Kim MRA Su-Jin Kim MS Hye-Jin Kim MRA Kwang-Suk Park MRA and Ji-Young Oh MRA for their devoted efforts to mining and clearing the KCCR data set

REFERENCES

1 Ministry Health and Welfare 2001 Annual report of Korea Central Cancer Registry (published in 2003) Available from URLhttpwwwnccrekr

2 WHO IARC Cancer Registration Principles and methods 1991 Lyon France

3 Shin HR Ahn YO Bae JM Shin MH Lee DH Lee CW Ohrr HC Ahn DH Ferlay J Parkin DM Oh DK Park JG Cancer Incidence in Korea Cancer Research and Treatment 2002 405-408

4 WHO IARC Cancer Incidence in Five Continents Volume VIII 2002

Appendix 1 List of the Hospitals participating in the 2001 KCCR program985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114

Ajou University Hospital

Andong General Hospital

Andong Presbyterian Hospital

Ansan Hando General Hospital

Asan Medical Center

Bag Ae Hospital

Benedict Hospital

Bupyeong Serim Hospital

Busan Veterans Hospital

Carollo Hospital

Catholic GEN Hospital

Changwon Fatima Hospital

Changwon General Hospital

ChonBuk National University Hospital

Chongju St Marys Hospital

Chonnam University Hospital

Choon Hae Hospital

Chosun University Hospital

Chung-Ang University Hospital

ChungAng University Medical Center

Chungbuk National University Hospital

Chungnam National University Hospital

College of Medicine Pochon CHA university CHA General Hospital

Dae Dong hospital

Dae Jeon Veterans Hospital

Dae Rim St Marys Hospital

Daegu Medical Center

Daewoo Hospital

DanKook University Hospital

Dong Kang General Hospital

Dong Rae Bong Seng Hospital

Dong-A University Hospital

Dongeui Medical Center

Dongguk University Kyong Ju Hospital

Dong-In Hospital

Dong-Kuk University Po-Hang Hospital

Dongsan Medical Center

Ewha Womans University Mokdong Hospital

Ewha Womans University Tongdaemun Hospital

Gachon Medical School Gil Medical Center

Gangneung Asan Hospital

Gangneung Medical Center

Gyeongsang University Hospital

Hae Dong Hospital

Halla General hospital

Hallym Sacred Heart Hospital

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

26 Cancer Research and Treatment 200436(1)

Appendix 1 Continued

985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114Hallym University Hang Gang Sacred Heart Hospital

Hallym University Medical Center ChunCheon Sacred Heart Hospital

Hangdong University Sunlin Presbyterian Hospital

Hanil Hospital

Hanyang University Hospital

Hanyang University Kuri Hospital

Holy Hamily Hospital

Il Sin Christian Hospital

In Je University Pusan Paik hospital

Inchon Christian Hospital

Inha University Hospital

Inha University Medical Center Inha Hospital

Inje Univ Ilsan Paik Hospital

Inje University Sanggye Paik Hospital

Inje University Seoul Paik Hospital

kang Dong Sacred Heart Hospital

Kangbuk Samsung Hospital

kangnam General Hospital Public Corporation

KangNam Sacred Heart Hospital Hallym University

Keimyung University Medical Center

Kon Kuk University Medical Center Seoul Hospital

Konyang University Hospital

Korea Cancer Center Hospital

Korea University Ansan Hospital

Korea University College of Medicine Guro Hospital

Korea University Hospital

Korea Veterans Hospital

Kosin University Gospel Hospital

Kwaks Hospital

Kwang Ju Christian Hospital

Kwang Ju Veterans Hospital

Kwang Myung Sung Ae General Hospital

Kwanghye General Hospital

Kyung Hee Medical Center

Kyungpook National University Hospital

Local Public Corp Inchun Medical Center

Local Public Corporation Chung Cheong Nam-do Hong Sung Medical Center

Maryknoll General Hospital

Masan Samsung Hospital

Mokpo Catholic Hospital

Moonhwa Hospital

Nam Kwang Hospital

National Cancer Center

National Health Insurance Corporation Ilsan Hospital

National Medical Center

National Police Hospital

Pochon Cha Univ Kumicha medical center

Pohang St Marys Hospital

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Hai-Rim Shin et alAnnual Report of the KCCR-2001 27

28 Cancer Research and Treatment 200436(1)

Appendix 1 Continued

985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114Presbyterian Medical Center

Pundang Je-Saeng Hospital

Pusan Adventist Hospital

Pusan Medical Center

Pusan National University Hospital

Samsun Hospital

Samsung Medical center

Sansung Cheil Hospital amp Womens Health Care Center

Sejong General Hospital

Seo San Medical Center

Seoul Adventist Hospital

Seoul Municipal Boramae Hospital

Seoul National University Hospital

Seoul Red Cross Hospital

Severance Hospital Yonsei University Medical College

Shin Chun Hospital

Soonchunhyang GuMi Hospital

Soonchunhyang University Cheonan Hospital

Soonchunyang Univ Hospital

St Marys hospital The Catholic University of Korea

St Francisco General Hospital

St Pauls Hospital

Sun General Hospital

Sung Ae Hospital

Taeback Choongang General Hospital

Taegu Catholic University Hospital

Taegu Fatima Hospital

The Catholic University of Korea Kangnam St Marys Hospital

The Catholic University of Korea Taejon St Marys Hospital

The Catholic University of Korea Our Lady of mercy Hospital

The Catholic University of Korea St Vincents Hospital

Uijongbu St Marys Hospital The Catholic University of Korea

Ulsan University Hospital

Wallace Memorial Baptist Hospital

WonJu Christian Hospital Won Ju Clooege of Medicine Yonsei University

WonKwang University Hospital

Yeungnam University Medical Center

Yeungnam University Youngchun Hospital

Yonsei Medical center Yong-Dong Severance Hospital

Young Dong Hospital985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Appendix 2 Marginal frequency of malignant cases by sexgender and ICD-10 grouping in 2001985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114

Male FemaleSite (code) 985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103}}}}}985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

n n 985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Lip (C00) 17 00 11 00

Tongue (C01~02) 209 04 79 02

Mouth (C03~06) 242 05 99 02

Salivary glands (C07~08) 136 03 107 03

Tonsil (C09) 109 02 15 00

Other oropharynx (C10) 46 01 6 00

Nasopharynx (C11) 218 04 81 02

Hypopharynx (C12~13) 239 05 14 00

Pharynx unspecified (C14) 27 01 3 00

Oesophagus (C15) 1416 27 120 03

Stomach (C16) 12356 239 6050 151

Small intestine (C17) 204 04 140 03

Colon (C18) 2620 51 2112 53

Rectum (C19~20) 2814 54 2073 52

Anus (C21) 59 01 62 02

Liver (C22) 8259 160 2596 65

Gallbladder etc(C23~24) 1361 26 1241 31

Pancreas (C25) 1187 23 854 21

Nose sinuses etc(C30~31) 148 03 81 02

Larynx (C32) 920 18 71 02

TrecheaTrachea bronchus and lung (C33~34) 8292 160 2632 65

Other thoracic organs (C37~38) 157 03 89 02

Bone (C40~41) 218 04 191 05

Melanoma of skin (C43) 112 02 111 03

Other skin (C44) 509 10 493 12

Mesothelioma (C45) 27 01 11 00

Kaposi sarcoma (C46) 7 00 6 00

Connective and soft tissue (C47~49) 294 06 251 06

Breast (C50) 36 01 6459 161

Vulva (C51) - - 67 02

Vagina (C52) - - 48 01

Cervix uteri (C53) - - 4054 101

Corpus uteri (C54) - - 739 18

Uterus unspecified (C55) - - 61 02

Ovary (C56) - - 1520 38

Other female genital organs (C57) - - 34 01

Placenta (C58) 0 00 69 02

Penis (C60) 44 01 - -

Prostate (C61) 1466 28 - -

Testis (C62) 133 03 - -

Other male genital organs (C63) 28 01 - -

Kidney (C64) 1011 20 465 12

Renal pelvis (C65) 128 02 29 01

Ureter (C66) 117 02 62 02

Bladder (C67) 1730 33 415 10

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Hai-Rim Shin et alAnnual Report of the KCCR-2001 29

Appendix 2 Continued985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114

Male FemaleSite (code) 985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103}}}}}}}}}985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

n n 985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Other urinary organs (C68) 21 00 24 01

Eye (C69) 51 01 40 01

Brain nervous system (C70~72) 609 12 489 12

Thyroid (C73) 551 11 3305 82

Adrenal gland (C74) 71 01 48 01

Other endocrine (C75) 46 01 20 00

Hodgkin disease (C81) 92 02 42 01

Non-Hodgkin lymphoma (C82~85 C96) 1185 23 793 20

Immunoproliferative diseases (C88) 9 00 0 00

Multiple myeloma (C90) 267 05 202 05

Lymphoid leukaemia (C91) 290 06 194 05

Myeloid leukaemia (C92~94) 645 12 555 14

Leukaemia unspecified (C95) 39 01 39 01

Other and unspecified 981 19 819 20 (C26 C39 C48 C76 C80 C97)

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

30 Cancer Research and Treatment 200436(1)

24 Cancer Research and Treatment 200436(1)

Table 4 Continued 985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114

Male Female985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103}}}985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103Topography Cases () Morphology Cases () Topography Cases () Morphology Cases ()

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103Breast (C50)985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Upper outer 2300 Infiltrating duct ca 5346

(356) (826)

Overlapping 839 Lobular ca 221

lesion (130) (34)

Upper inner 752 Mucinous adeno ca 144

(116) (22)

Lower outer 371 Medullary ca 116

(57) (18)

Central portion 329 Papillary ca 80

(51) (12)

1878 562

(290) (87)985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103Rectum (C19-C20)985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103Rectum NOS 2501 Adenocarcinoma 1762 Rectum NOS 1850 Adenocarcinoma 1261

(888) (625) (889) (606)

Rectosigmoid 316 Tubular adeno ca 677 Rectosigmoid 232 Tubular adeno ca 478

junction (112) (240) junction (111) (230)

Mucinous adeno ca 73 Mucinous adeno ca 66

(26) (32)

Carcinoid tumor 48 Papillary adeno ca 48

(17) (23)

Papillary adeno ca 48 Carcinoid tumor 28

(17) (13)

209 201

(74) (97)985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103Colon (C18)985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103}Sigmoid colon 1057 Adenocarcinoma 1593 Sigmoid colon 763 Adenocarcinoma 1286

(600) (357) (398) (601)

Ascending colon 494 Tubular adeno ca 559 Ascending colon 517 Tubular adeno ca 431

(186) (210) (242) (201)

Transverse colon 206 Mucinous adeno ca 163 Transverse colon 162 Mucinous adeno ca 149

(78) (61) (76) (70)

Descending colon 152 Papillary adeno ca 67 Cecum 136 Papillary adeno ca 40

(57) (25) (64) (19)

Cecum 126 Malig Lymphoma 26 Descending colon 101 Malig Lymphoma 15

(47) large cell diffuse (10) (47) large cell diffuse (07)

622 249 460 218

(234) (94) (215) (102)

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Hai-Rim Shin et alAnnual Report of the KCCR-2001 25

in 1980 In the beginning 47 nationwide resident-training general hospitals participated in this program The number of participating hospitals and registered malignancies has incre-ased year-by-year with 134 hospitals submitting their data diskettes in 2001 (1) The number of cancer cases in the KCCR for 2000 was assumed to be more than 90 precise for cancer cases with the comparison of the estimated cancer incidence cases (3) using national mortality data and the incidence data from four frontier regional cancer registries including Kangwha Seoul Busan and Daegu in the Cancer Incidence in Five Continents (4) The KCCR database is especially useful for showing the trend of cancer occurrence in Korea as information on the changing trend of cancer incidence over time is an essential component in the planning and monitoring of programs for cancer prevention early detection and treatment Major cancers including stomach lung liver breast and colorectum but with the exception of uterine cervix cancer were increasing (data not shown) For uterine cervix cancer the proportion of carcinoma in-situ cases increased among the registered cases meaning significant uterine cervix cancers were detected at an early stage Currently KCCR being a nationwide hospital-based cancer registry is supporting technically and financially 9 population- based regional registries Seoul Busan Daegu Incheon Gwangju Daejeon Ulsan Jejudo and Goyang-si in 2003 The KCCR database continues to hold the most important position until a nationwide population-based data acquisition program can be constructed on the basis of international standards One area for caution in the interpretation of the KCCR data

is that the numbers outlined in this report do not represent persons but cases that have been reported The patients who had cancers at several sites have been treated as multiple primary patients and have been reported according to the cancer site

ACKNOWLEDGEMENTS

We would like to sincerely thank the participation of the medical record administrators in the KCCR-affiliated hospitals [Appendix 1] who enthusiastically participated in the KCCR by registering new cancer cases We would also like to thank Ji-Young Kim MRA Su-Jin Kim MS Hye-Jin Kim MRA Kwang-Suk Park MRA and Ji-Young Oh MRA for their devoted efforts to mining and clearing the KCCR data set

REFERENCES

1 Ministry Health and Welfare 2001 Annual report of Korea Central Cancer Registry (published in 2003) Available from URLhttpwwwnccrekr

2 WHO IARC Cancer Registration Principles and methods 1991 Lyon France

3 Shin HR Ahn YO Bae JM Shin MH Lee DH Lee CW Ohrr HC Ahn DH Ferlay J Parkin DM Oh DK Park JG Cancer Incidence in Korea Cancer Research and Treatment 2002 405-408

4 WHO IARC Cancer Incidence in Five Continents Volume VIII 2002

Appendix 1 List of the Hospitals participating in the 2001 KCCR program985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114

Ajou University Hospital

Andong General Hospital

Andong Presbyterian Hospital

Ansan Hando General Hospital

Asan Medical Center

Bag Ae Hospital

Benedict Hospital

Bupyeong Serim Hospital

Busan Veterans Hospital

Carollo Hospital

Catholic GEN Hospital

Changwon Fatima Hospital

Changwon General Hospital

ChonBuk National University Hospital

Chongju St Marys Hospital

Chonnam University Hospital

Choon Hae Hospital

Chosun University Hospital

Chung-Ang University Hospital

ChungAng University Medical Center

Chungbuk National University Hospital

Chungnam National University Hospital

College of Medicine Pochon CHA university CHA General Hospital

Dae Dong hospital

Dae Jeon Veterans Hospital

Dae Rim St Marys Hospital

Daegu Medical Center

Daewoo Hospital

DanKook University Hospital

Dong Kang General Hospital

Dong Rae Bong Seng Hospital

Dong-A University Hospital

Dongeui Medical Center

Dongguk University Kyong Ju Hospital

Dong-In Hospital

Dong-Kuk University Po-Hang Hospital

Dongsan Medical Center

Ewha Womans University Mokdong Hospital

Ewha Womans University Tongdaemun Hospital

Gachon Medical School Gil Medical Center

Gangneung Asan Hospital

Gangneung Medical Center

Gyeongsang University Hospital

Hae Dong Hospital

Halla General hospital

Hallym Sacred Heart Hospital

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

26 Cancer Research and Treatment 200436(1)

Appendix 1 Continued

985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114Hallym University Hang Gang Sacred Heart Hospital

Hallym University Medical Center ChunCheon Sacred Heart Hospital

Hangdong University Sunlin Presbyterian Hospital

Hanil Hospital

Hanyang University Hospital

Hanyang University Kuri Hospital

Holy Hamily Hospital

Il Sin Christian Hospital

In Je University Pusan Paik hospital

Inchon Christian Hospital

Inha University Hospital

Inha University Medical Center Inha Hospital

Inje Univ Ilsan Paik Hospital

Inje University Sanggye Paik Hospital

Inje University Seoul Paik Hospital

kang Dong Sacred Heart Hospital

Kangbuk Samsung Hospital

kangnam General Hospital Public Corporation

KangNam Sacred Heart Hospital Hallym University

Keimyung University Medical Center

Kon Kuk University Medical Center Seoul Hospital

Konyang University Hospital

Korea Cancer Center Hospital

Korea University Ansan Hospital

Korea University College of Medicine Guro Hospital

Korea University Hospital

Korea Veterans Hospital

Kosin University Gospel Hospital

Kwaks Hospital

Kwang Ju Christian Hospital

Kwang Ju Veterans Hospital

Kwang Myung Sung Ae General Hospital

Kwanghye General Hospital

Kyung Hee Medical Center

Kyungpook National University Hospital

Local Public Corp Inchun Medical Center

Local Public Corporation Chung Cheong Nam-do Hong Sung Medical Center

Maryknoll General Hospital

Masan Samsung Hospital

Mokpo Catholic Hospital

Moonhwa Hospital

Nam Kwang Hospital

National Cancer Center

National Health Insurance Corporation Ilsan Hospital

National Medical Center

National Police Hospital

Pochon Cha Univ Kumicha medical center

Pohang St Marys Hospital

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Hai-Rim Shin et alAnnual Report of the KCCR-2001 27

28 Cancer Research and Treatment 200436(1)

Appendix 1 Continued

985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114Presbyterian Medical Center

Pundang Je-Saeng Hospital

Pusan Adventist Hospital

Pusan Medical Center

Pusan National University Hospital

Samsun Hospital

Samsung Medical center

Sansung Cheil Hospital amp Womens Health Care Center

Sejong General Hospital

Seo San Medical Center

Seoul Adventist Hospital

Seoul Municipal Boramae Hospital

Seoul National University Hospital

Seoul Red Cross Hospital

Severance Hospital Yonsei University Medical College

Shin Chun Hospital

Soonchunhyang GuMi Hospital

Soonchunhyang University Cheonan Hospital

Soonchunyang Univ Hospital

St Marys hospital The Catholic University of Korea

St Francisco General Hospital

St Pauls Hospital

Sun General Hospital

Sung Ae Hospital

Taeback Choongang General Hospital

Taegu Catholic University Hospital

Taegu Fatima Hospital

The Catholic University of Korea Kangnam St Marys Hospital

The Catholic University of Korea Taejon St Marys Hospital

The Catholic University of Korea Our Lady of mercy Hospital

The Catholic University of Korea St Vincents Hospital

Uijongbu St Marys Hospital The Catholic University of Korea

Ulsan University Hospital

Wallace Memorial Baptist Hospital

WonJu Christian Hospital Won Ju Clooege of Medicine Yonsei University

WonKwang University Hospital

Yeungnam University Medical Center

Yeungnam University Youngchun Hospital

Yonsei Medical center Yong-Dong Severance Hospital

Young Dong Hospital985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Appendix 2 Marginal frequency of malignant cases by sexgender and ICD-10 grouping in 2001985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114

Male FemaleSite (code) 985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103}}}}}985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

n n 985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Lip (C00) 17 00 11 00

Tongue (C01~02) 209 04 79 02

Mouth (C03~06) 242 05 99 02

Salivary glands (C07~08) 136 03 107 03

Tonsil (C09) 109 02 15 00

Other oropharynx (C10) 46 01 6 00

Nasopharynx (C11) 218 04 81 02

Hypopharynx (C12~13) 239 05 14 00

Pharynx unspecified (C14) 27 01 3 00

Oesophagus (C15) 1416 27 120 03

Stomach (C16) 12356 239 6050 151

Small intestine (C17) 204 04 140 03

Colon (C18) 2620 51 2112 53

Rectum (C19~20) 2814 54 2073 52

Anus (C21) 59 01 62 02

Liver (C22) 8259 160 2596 65

Gallbladder etc(C23~24) 1361 26 1241 31

Pancreas (C25) 1187 23 854 21

Nose sinuses etc(C30~31) 148 03 81 02

Larynx (C32) 920 18 71 02

TrecheaTrachea bronchus and lung (C33~34) 8292 160 2632 65

Other thoracic organs (C37~38) 157 03 89 02

Bone (C40~41) 218 04 191 05

Melanoma of skin (C43) 112 02 111 03

Other skin (C44) 509 10 493 12

Mesothelioma (C45) 27 01 11 00

Kaposi sarcoma (C46) 7 00 6 00

Connective and soft tissue (C47~49) 294 06 251 06

Breast (C50) 36 01 6459 161

Vulva (C51) - - 67 02

Vagina (C52) - - 48 01

Cervix uteri (C53) - - 4054 101

Corpus uteri (C54) - - 739 18

Uterus unspecified (C55) - - 61 02

Ovary (C56) - - 1520 38

Other female genital organs (C57) - - 34 01

Placenta (C58) 0 00 69 02

Penis (C60) 44 01 - -

Prostate (C61) 1466 28 - -

Testis (C62) 133 03 - -

Other male genital organs (C63) 28 01 - -

Kidney (C64) 1011 20 465 12

Renal pelvis (C65) 128 02 29 01

Ureter (C66) 117 02 62 02

Bladder (C67) 1730 33 415 10

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Hai-Rim Shin et alAnnual Report of the KCCR-2001 29

Appendix 2 Continued985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114

Male FemaleSite (code) 985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103}}}}}}}}}985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

n n 985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Other urinary organs (C68) 21 00 24 01

Eye (C69) 51 01 40 01

Brain nervous system (C70~72) 609 12 489 12

Thyroid (C73) 551 11 3305 82

Adrenal gland (C74) 71 01 48 01

Other endocrine (C75) 46 01 20 00

Hodgkin disease (C81) 92 02 42 01

Non-Hodgkin lymphoma (C82~85 C96) 1185 23 793 20

Immunoproliferative diseases (C88) 9 00 0 00

Multiple myeloma (C90) 267 05 202 05

Lymphoid leukaemia (C91) 290 06 194 05

Myeloid leukaemia (C92~94) 645 12 555 14

Leukaemia unspecified (C95) 39 01 39 01

Other and unspecified 981 19 819 20 (C26 C39 C48 C76 C80 C97)

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

30 Cancer Research and Treatment 200436(1)

Hai-Rim Shin et alAnnual Report of the KCCR-2001 25

in 1980 In the beginning 47 nationwide resident-training general hospitals participated in this program The number of participating hospitals and registered malignancies has incre-ased year-by-year with 134 hospitals submitting their data diskettes in 2001 (1) The number of cancer cases in the KCCR for 2000 was assumed to be more than 90 precise for cancer cases with the comparison of the estimated cancer incidence cases (3) using national mortality data and the incidence data from four frontier regional cancer registries including Kangwha Seoul Busan and Daegu in the Cancer Incidence in Five Continents (4) The KCCR database is especially useful for showing the trend of cancer occurrence in Korea as information on the changing trend of cancer incidence over time is an essential component in the planning and monitoring of programs for cancer prevention early detection and treatment Major cancers including stomach lung liver breast and colorectum but with the exception of uterine cervix cancer were increasing (data not shown) For uterine cervix cancer the proportion of carcinoma in-situ cases increased among the registered cases meaning significant uterine cervix cancers were detected at an early stage Currently KCCR being a nationwide hospital-based cancer registry is supporting technically and financially 9 population- based regional registries Seoul Busan Daegu Incheon Gwangju Daejeon Ulsan Jejudo and Goyang-si in 2003 The KCCR database continues to hold the most important position until a nationwide population-based data acquisition program can be constructed on the basis of international standards One area for caution in the interpretation of the KCCR data

is that the numbers outlined in this report do not represent persons but cases that have been reported The patients who had cancers at several sites have been treated as multiple primary patients and have been reported according to the cancer site

ACKNOWLEDGEMENTS

We would like to sincerely thank the participation of the medical record administrators in the KCCR-affiliated hospitals [Appendix 1] who enthusiastically participated in the KCCR by registering new cancer cases We would also like to thank Ji-Young Kim MRA Su-Jin Kim MS Hye-Jin Kim MRA Kwang-Suk Park MRA and Ji-Young Oh MRA for their devoted efforts to mining and clearing the KCCR data set

REFERENCES

1 Ministry Health and Welfare 2001 Annual report of Korea Central Cancer Registry (published in 2003) Available from URLhttpwwwnccrekr

2 WHO IARC Cancer Registration Principles and methods 1991 Lyon France

3 Shin HR Ahn YO Bae JM Shin MH Lee DH Lee CW Ohrr HC Ahn DH Ferlay J Parkin DM Oh DK Park JG Cancer Incidence in Korea Cancer Research and Treatment 2002 405-408

4 WHO IARC Cancer Incidence in Five Continents Volume VIII 2002

Appendix 1 List of the Hospitals participating in the 2001 KCCR program985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114

Ajou University Hospital

Andong General Hospital

Andong Presbyterian Hospital

Ansan Hando General Hospital

Asan Medical Center

Bag Ae Hospital

Benedict Hospital

Bupyeong Serim Hospital

Busan Veterans Hospital

Carollo Hospital

Catholic GEN Hospital

Changwon Fatima Hospital

Changwon General Hospital

ChonBuk National University Hospital

Chongju St Marys Hospital

Chonnam University Hospital

Choon Hae Hospital

Chosun University Hospital

Chung-Ang University Hospital

ChungAng University Medical Center

Chungbuk National University Hospital

Chungnam National University Hospital

College of Medicine Pochon CHA university CHA General Hospital

Dae Dong hospital

Dae Jeon Veterans Hospital

Dae Rim St Marys Hospital

Daegu Medical Center

Daewoo Hospital

DanKook University Hospital

Dong Kang General Hospital

Dong Rae Bong Seng Hospital

Dong-A University Hospital

Dongeui Medical Center

Dongguk University Kyong Ju Hospital

Dong-In Hospital

Dong-Kuk University Po-Hang Hospital

Dongsan Medical Center

Ewha Womans University Mokdong Hospital

Ewha Womans University Tongdaemun Hospital

Gachon Medical School Gil Medical Center

Gangneung Asan Hospital

Gangneung Medical Center

Gyeongsang University Hospital

Hae Dong Hospital

Halla General hospital

Hallym Sacred Heart Hospital

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

26 Cancer Research and Treatment 200436(1)

Appendix 1 Continued

985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114Hallym University Hang Gang Sacred Heart Hospital

Hallym University Medical Center ChunCheon Sacred Heart Hospital

Hangdong University Sunlin Presbyterian Hospital

Hanil Hospital

Hanyang University Hospital

Hanyang University Kuri Hospital

Holy Hamily Hospital

Il Sin Christian Hospital

In Je University Pusan Paik hospital

Inchon Christian Hospital

Inha University Hospital

Inha University Medical Center Inha Hospital

Inje Univ Ilsan Paik Hospital

Inje University Sanggye Paik Hospital

Inje University Seoul Paik Hospital

kang Dong Sacred Heart Hospital

Kangbuk Samsung Hospital

kangnam General Hospital Public Corporation

KangNam Sacred Heart Hospital Hallym University

Keimyung University Medical Center

Kon Kuk University Medical Center Seoul Hospital

Konyang University Hospital

Korea Cancer Center Hospital

Korea University Ansan Hospital

Korea University College of Medicine Guro Hospital

Korea University Hospital

Korea Veterans Hospital

Kosin University Gospel Hospital

Kwaks Hospital

Kwang Ju Christian Hospital

Kwang Ju Veterans Hospital

Kwang Myung Sung Ae General Hospital

Kwanghye General Hospital

Kyung Hee Medical Center

Kyungpook National University Hospital

Local Public Corp Inchun Medical Center

Local Public Corporation Chung Cheong Nam-do Hong Sung Medical Center

Maryknoll General Hospital

Masan Samsung Hospital

Mokpo Catholic Hospital

Moonhwa Hospital

Nam Kwang Hospital

National Cancer Center

National Health Insurance Corporation Ilsan Hospital

National Medical Center

National Police Hospital

Pochon Cha Univ Kumicha medical center

Pohang St Marys Hospital

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Hai-Rim Shin et alAnnual Report of the KCCR-2001 27

28 Cancer Research and Treatment 200436(1)

Appendix 1 Continued

985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114Presbyterian Medical Center

Pundang Je-Saeng Hospital

Pusan Adventist Hospital

Pusan Medical Center

Pusan National University Hospital

Samsun Hospital

Samsung Medical center

Sansung Cheil Hospital amp Womens Health Care Center

Sejong General Hospital

Seo San Medical Center

Seoul Adventist Hospital

Seoul Municipal Boramae Hospital

Seoul National University Hospital

Seoul Red Cross Hospital

Severance Hospital Yonsei University Medical College

Shin Chun Hospital

Soonchunhyang GuMi Hospital

Soonchunhyang University Cheonan Hospital

Soonchunyang Univ Hospital

St Marys hospital The Catholic University of Korea

St Francisco General Hospital

St Pauls Hospital

Sun General Hospital

Sung Ae Hospital

Taeback Choongang General Hospital

Taegu Catholic University Hospital

Taegu Fatima Hospital

The Catholic University of Korea Kangnam St Marys Hospital

The Catholic University of Korea Taejon St Marys Hospital

The Catholic University of Korea Our Lady of mercy Hospital

The Catholic University of Korea St Vincents Hospital

Uijongbu St Marys Hospital The Catholic University of Korea

Ulsan University Hospital

Wallace Memorial Baptist Hospital

WonJu Christian Hospital Won Ju Clooege of Medicine Yonsei University

WonKwang University Hospital

Yeungnam University Medical Center

Yeungnam University Youngchun Hospital

Yonsei Medical center Yong-Dong Severance Hospital

Young Dong Hospital985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Appendix 2 Marginal frequency of malignant cases by sexgender and ICD-10 grouping in 2001985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114

Male FemaleSite (code) 985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103}}}}}985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

n n 985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Lip (C00) 17 00 11 00

Tongue (C01~02) 209 04 79 02

Mouth (C03~06) 242 05 99 02

Salivary glands (C07~08) 136 03 107 03

Tonsil (C09) 109 02 15 00

Other oropharynx (C10) 46 01 6 00

Nasopharynx (C11) 218 04 81 02

Hypopharynx (C12~13) 239 05 14 00

Pharynx unspecified (C14) 27 01 3 00

Oesophagus (C15) 1416 27 120 03

Stomach (C16) 12356 239 6050 151

Small intestine (C17) 204 04 140 03

Colon (C18) 2620 51 2112 53

Rectum (C19~20) 2814 54 2073 52

Anus (C21) 59 01 62 02

Liver (C22) 8259 160 2596 65

Gallbladder etc(C23~24) 1361 26 1241 31

Pancreas (C25) 1187 23 854 21

Nose sinuses etc(C30~31) 148 03 81 02

Larynx (C32) 920 18 71 02

TrecheaTrachea bronchus and lung (C33~34) 8292 160 2632 65

Other thoracic organs (C37~38) 157 03 89 02

Bone (C40~41) 218 04 191 05

Melanoma of skin (C43) 112 02 111 03

Other skin (C44) 509 10 493 12

Mesothelioma (C45) 27 01 11 00

Kaposi sarcoma (C46) 7 00 6 00

Connective and soft tissue (C47~49) 294 06 251 06

Breast (C50) 36 01 6459 161

Vulva (C51) - - 67 02

Vagina (C52) - - 48 01

Cervix uteri (C53) - - 4054 101

Corpus uteri (C54) - - 739 18

Uterus unspecified (C55) - - 61 02

Ovary (C56) - - 1520 38

Other female genital organs (C57) - - 34 01

Placenta (C58) 0 00 69 02

Penis (C60) 44 01 - -

Prostate (C61) 1466 28 - -

Testis (C62) 133 03 - -

Other male genital organs (C63) 28 01 - -

Kidney (C64) 1011 20 465 12

Renal pelvis (C65) 128 02 29 01

Ureter (C66) 117 02 62 02

Bladder (C67) 1730 33 415 10

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Hai-Rim Shin et alAnnual Report of the KCCR-2001 29

Appendix 2 Continued985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114

Male FemaleSite (code) 985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103}}}}}}}}}985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

n n 985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Other urinary organs (C68) 21 00 24 01

Eye (C69) 51 01 40 01

Brain nervous system (C70~72) 609 12 489 12

Thyroid (C73) 551 11 3305 82

Adrenal gland (C74) 71 01 48 01

Other endocrine (C75) 46 01 20 00

Hodgkin disease (C81) 92 02 42 01

Non-Hodgkin lymphoma (C82~85 C96) 1185 23 793 20

Immunoproliferative diseases (C88) 9 00 0 00

Multiple myeloma (C90) 267 05 202 05

Lymphoid leukaemia (C91) 290 06 194 05

Myeloid leukaemia (C92~94) 645 12 555 14

Leukaemia unspecified (C95) 39 01 39 01

Other and unspecified 981 19 819 20 (C26 C39 C48 C76 C80 C97)

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

30 Cancer Research and Treatment 200436(1)

Appendix 1 List of the Hospitals participating in the 2001 KCCR program985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114

Ajou University Hospital

Andong General Hospital

Andong Presbyterian Hospital

Ansan Hando General Hospital

Asan Medical Center

Bag Ae Hospital

Benedict Hospital

Bupyeong Serim Hospital

Busan Veterans Hospital

Carollo Hospital

Catholic GEN Hospital

Changwon Fatima Hospital

Changwon General Hospital

ChonBuk National University Hospital

Chongju St Marys Hospital

Chonnam University Hospital

Choon Hae Hospital

Chosun University Hospital

Chung-Ang University Hospital

ChungAng University Medical Center

Chungbuk National University Hospital

Chungnam National University Hospital

College of Medicine Pochon CHA university CHA General Hospital

Dae Dong hospital

Dae Jeon Veterans Hospital

Dae Rim St Marys Hospital

Daegu Medical Center

Daewoo Hospital

DanKook University Hospital

Dong Kang General Hospital

Dong Rae Bong Seng Hospital

Dong-A University Hospital

Dongeui Medical Center

Dongguk University Kyong Ju Hospital

Dong-In Hospital

Dong-Kuk University Po-Hang Hospital

Dongsan Medical Center

Ewha Womans University Mokdong Hospital

Ewha Womans University Tongdaemun Hospital

Gachon Medical School Gil Medical Center

Gangneung Asan Hospital

Gangneung Medical Center

Gyeongsang University Hospital

Hae Dong Hospital

Halla General hospital

Hallym Sacred Heart Hospital

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

26 Cancer Research and Treatment 200436(1)

Appendix 1 Continued

985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114Hallym University Hang Gang Sacred Heart Hospital

Hallym University Medical Center ChunCheon Sacred Heart Hospital

Hangdong University Sunlin Presbyterian Hospital

Hanil Hospital

Hanyang University Hospital

Hanyang University Kuri Hospital

Holy Hamily Hospital

Il Sin Christian Hospital

In Je University Pusan Paik hospital

Inchon Christian Hospital

Inha University Hospital

Inha University Medical Center Inha Hospital

Inje Univ Ilsan Paik Hospital

Inje University Sanggye Paik Hospital

Inje University Seoul Paik Hospital

kang Dong Sacred Heart Hospital

Kangbuk Samsung Hospital

kangnam General Hospital Public Corporation

KangNam Sacred Heart Hospital Hallym University

Keimyung University Medical Center

Kon Kuk University Medical Center Seoul Hospital

Konyang University Hospital

Korea Cancer Center Hospital

Korea University Ansan Hospital

Korea University College of Medicine Guro Hospital

Korea University Hospital

Korea Veterans Hospital

Kosin University Gospel Hospital

Kwaks Hospital

Kwang Ju Christian Hospital

Kwang Ju Veterans Hospital

Kwang Myung Sung Ae General Hospital

Kwanghye General Hospital

Kyung Hee Medical Center

Kyungpook National University Hospital

Local Public Corp Inchun Medical Center

Local Public Corporation Chung Cheong Nam-do Hong Sung Medical Center

Maryknoll General Hospital

Masan Samsung Hospital

Mokpo Catholic Hospital

Moonhwa Hospital

Nam Kwang Hospital

National Cancer Center

National Health Insurance Corporation Ilsan Hospital

National Medical Center

National Police Hospital

Pochon Cha Univ Kumicha medical center

Pohang St Marys Hospital

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Hai-Rim Shin et alAnnual Report of the KCCR-2001 27

28 Cancer Research and Treatment 200436(1)

Appendix 1 Continued

985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114Presbyterian Medical Center

Pundang Je-Saeng Hospital

Pusan Adventist Hospital

Pusan Medical Center

Pusan National University Hospital

Samsun Hospital

Samsung Medical center

Sansung Cheil Hospital amp Womens Health Care Center

Sejong General Hospital

Seo San Medical Center

Seoul Adventist Hospital

Seoul Municipal Boramae Hospital

Seoul National University Hospital

Seoul Red Cross Hospital

Severance Hospital Yonsei University Medical College

Shin Chun Hospital

Soonchunhyang GuMi Hospital

Soonchunhyang University Cheonan Hospital

Soonchunyang Univ Hospital

St Marys hospital The Catholic University of Korea

St Francisco General Hospital

St Pauls Hospital

Sun General Hospital

Sung Ae Hospital

Taeback Choongang General Hospital

Taegu Catholic University Hospital

Taegu Fatima Hospital

The Catholic University of Korea Kangnam St Marys Hospital

The Catholic University of Korea Taejon St Marys Hospital

The Catholic University of Korea Our Lady of mercy Hospital

The Catholic University of Korea St Vincents Hospital

Uijongbu St Marys Hospital The Catholic University of Korea

Ulsan University Hospital

Wallace Memorial Baptist Hospital

WonJu Christian Hospital Won Ju Clooege of Medicine Yonsei University

WonKwang University Hospital

Yeungnam University Medical Center

Yeungnam University Youngchun Hospital

Yonsei Medical center Yong-Dong Severance Hospital

Young Dong Hospital985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Appendix 2 Marginal frequency of malignant cases by sexgender and ICD-10 grouping in 2001985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114

Male FemaleSite (code) 985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103}}}}}985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

n n 985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Lip (C00) 17 00 11 00

Tongue (C01~02) 209 04 79 02

Mouth (C03~06) 242 05 99 02

Salivary glands (C07~08) 136 03 107 03

Tonsil (C09) 109 02 15 00

Other oropharynx (C10) 46 01 6 00

Nasopharynx (C11) 218 04 81 02

Hypopharynx (C12~13) 239 05 14 00

Pharynx unspecified (C14) 27 01 3 00

Oesophagus (C15) 1416 27 120 03

Stomach (C16) 12356 239 6050 151

Small intestine (C17) 204 04 140 03

Colon (C18) 2620 51 2112 53

Rectum (C19~20) 2814 54 2073 52

Anus (C21) 59 01 62 02

Liver (C22) 8259 160 2596 65

Gallbladder etc(C23~24) 1361 26 1241 31

Pancreas (C25) 1187 23 854 21

Nose sinuses etc(C30~31) 148 03 81 02

Larynx (C32) 920 18 71 02

TrecheaTrachea bronchus and lung (C33~34) 8292 160 2632 65

Other thoracic organs (C37~38) 157 03 89 02

Bone (C40~41) 218 04 191 05

Melanoma of skin (C43) 112 02 111 03

Other skin (C44) 509 10 493 12

Mesothelioma (C45) 27 01 11 00

Kaposi sarcoma (C46) 7 00 6 00

Connective and soft tissue (C47~49) 294 06 251 06

Breast (C50) 36 01 6459 161

Vulva (C51) - - 67 02

Vagina (C52) - - 48 01

Cervix uteri (C53) - - 4054 101

Corpus uteri (C54) - - 739 18

Uterus unspecified (C55) - - 61 02

Ovary (C56) - - 1520 38

Other female genital organs (C57) - - 34 01

Placenta (C58) 0 00 69 02

Penis (C60) 44 01 - -

Prostate (C61) 1466 28 - -

Testis (C62) 133 03 - -

Other male genital organs (C63) 28 01 - -

Kidney (C64) 1011 20 465 12

Renal pelvis (C65) 128 02 29 01

Ureter (C66) 117 02 62 02

Bladder (C67) 1730 33 415 10

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Hai-Rim Shin et alAnnual Report of the KCCR-2001 29

Appendix 2 Continued985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114

Male FemaleSite (code) 985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103}}}}}}}}}985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

n n 985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Other urinary organs (C68) 21 00 24 01

Eye (C69) 51 01 40 01

Brain nervous system (C70~72) 609 12 489 12

Thyroid (C73) 551 11 3305 82

Adrenal gland (C74) 71 01 48 01

Other endocrine (C75) 46 01 20 00

Hodgkin disease (C81) 92 02 42 01

Non-Hodgkin lymphoma (C82~85 C96) 1185 23 793 20

Immunoproliferative diseases (C88) 9 00 0 00

Multiple myeloma (C90) 267 05 202 05

Lymphoid leukaemia (C91) 290 06 194 05

Myeloid leukaemia (C92~94) 645 12 555 14

Leukaemia unspecified (C95) 39 01 39 01

Other and unspecified 981 19 819 20 (C26 C39 C48 C76 C80 C97)

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

30 Cancer Research and Treatment 200436(1)

Appendix 1 Continued

985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114Hallym University Hang Gang Sacred Heart Hospital

Hallym University Medical Center ChunCheon Sacred Heart Hospital

Hangdong University Sunlin Presbyterian Hospital

Hanil Hospital

Hanyang University Hospital

Hanyang University Kuri Hospital

Holy Hamily Hospital

Il Sin Christian Hospital

In Je University Pusan Paik hospital

Inchon Christian Hospital

Inha University Hospital

Inha University Medical Center Inha Hospital

Inje Univ Ilsan Paik Hospital

Inje University Sanggye Paik Hospital

Inje University Seoul Paik Hospital

kang Dong Sacred Heart Hospital

Kangbuk Samsung Hospital

kangnam General Hospital Public Corporation

KangNam Sacred Heart Hospital Hallym University

Keimyung University Medical Center

Kon Kuk University Medical Center Seoul Hospital

Konyang University Hospital

Korea Cancer Center Hospital

Korea University Ansan Hospital

Korea University College of Medicine Guro Hospital

Korea University Hospital

Korea Veterans Hospital

Kosin University Gospel Hospital

Kwaks Hospital

Kwang Ju Christian Hospital

Kwang Ju Veterans Hospital

Kwang Myung Sung Ae General Hospital

Kwanghye General Hospital

Kyung Hee Medical Center

Kyungpook National University Hospital

Local Public Corp Inchun Medical Center

Local Public Corporation Chung Cheong Nam-do Hong Sung Medical Center

Maryknoll General Hospital

Masan Samsung Hospital

Mokpo Catholic Hospital

Moonhwa Hospital

Nam Kwang Hospital

National Cancer Center

National Health Insurance Corporation Ilsan Hospital

National Medical Center

National Police Hospital

Pochon Cha Univ Kumicha medical center

Pohang St Marys Hospital

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Hai-Rim Shin et alAnnual Report of the KCCR-2001 27

28 Cancer Research and Treatment 200436(1)

Appendix 1 Continued

985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114Presbyterian Medical Center

Pundang Je-Saeng Hospital

Pusan Adventist Hospital

Pusan Medical Center

Pusan National University Hospital

Samsun Hospital

Samsung Medical center

Sansung Cheil Hospital amp Womens Health Care Center

Sejong General Hospital

Seo San Medical Center

Seoul Adventist Hospital

Seoul Municipal Boramae Hospital

Seoul National University Hospital

Seoul Red Cross Hospital

Severance Hospital Yonsei University Medical College

Shin Chun Hospital

Soonchunhyang GuMi Hospital

Soonchunhyang University Cheonan Hospital

Soonchunyang Univ Hospital

St Marys hospital The Catholic University of Korea

St Francisco General Hospital

St Pauls Hospital

Sun General Hospital

Sung Ae Hospital

Taeback Choongang General Hospital

Taegu Catholic University Hospital

Taegu Fatima Hospital

The Catholic University of Korea Kangnam St Marys Hospital

The Catholic University of Korea Taejon St Marys Hospital

The Catholic University of Korea Our Lady of mercy Hospital

The Catholic University of Korea St Vincents Hospital

Uijongbu St Marys Hospital The Catholic University of Korea

Ulsan University Hospital

Wallace Memorial Baptist Hospital

WonJu Christian Hospital Won Ju Clooege of Medicine Yonsei University

WonKwang University Hospital

Yeungnam University Medical Center

Yeungnam University Youngchun Hospital

Yonsei Medical center Yong-Dong Severance Hospital

Young Dong Hospital985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Appendix 2 Marginal frequency of malignant cases by sexgender and ICD-10 grouping in 2001985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114

Male FemaleSite (code) 985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103}}}}}985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

n n 985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Lip (C00) 17 00 11 00

Tongue (C01~02) 209 04 79 02

Mouth (C03~06) 242 05 99 02

Salivary glands (C07~08) 136 03 107 03

Tonsil (C09) 109 02 15 00

Other oropharynx (C10) 46 01 6 00

Nasopharynx (C11) 218 04 81 02

Hypopharynx (C12~13) 239 05 14 00

Pharynx unspecified (C14) 27 01 3 00

Oesophagus (C15) 1416 27 120 03

Stomach (C16) 12356 239 6050 151

Small intestine (C17) 204 04 140 03

Colon (C18) 2620 51 2112 53

Rectum (C19~20) 2814 54 2073 52

Anus (C21) 59 01 62 02

Liver (C22) 8259 160 2596 65

Gallbladder etc(C23~24) 1361 26 1241 31

Pancreas (C25) 1187 23 854 21

Nose sinuses etc(C30~31) 148 03 81 02

Larynx (C32) 920 18 71 02

TrecheaTrachea bronchus and lung (C33~34) 8292 160 2632 65

Other thoracic organs (C37~38) 157 03 89 02

Bone (C40~41) 218 04 191 05

Melanoma of skin (C43) 112 02 111 03

Other skin (C44) 509 10 493 12

Mesothelioma (C45) 27 01 11 00

Kaposi sarcoma (C46) 7 00 6 00

Connective and soft tissue (C47~49) 294 06 251 06

Breast (C50) 36 01 6459 161

Vulva (C51) - - 67 02

Vagina (C52) - - 48 01

Cervix uteri (C53) - - 4054 101

Corpus uteri (C54) - - 739 18

Uterus unspecified (C55) - - 61 02

Ovary (C56) - - 1520 38

Other female genital organs (C57) - - 34 01

Placenta (C58) 0 00 69 02

Penis (C60) 44 01 - -

Prostate (C61) 1466 28 - -

Testis (C62) 133 03 - -

Other male genital organs (C63) 28 01 - -

Kidney (C64) 1011 20 465 12

Renal pelvis (C65) 128 02 29 01

Ureter (C66) 117 02 62 02

Bladder (C67) 1730 33 415 10

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Hai-Rim Shin et alAnnual Report of the KCCR-2001 29

Appendix 2 Continued985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114

Male FemaleSite (code) 985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103}}}}}}}}}985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

n n 985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Other urinary organs (C68) 21 00 24 01

Eye (C69) 51 01 40 01

Brain nervous system (C70~72) 609 12 489 12

Thyroid (C73) 551 11 3305 82

Adrenal gland (C74) 71 01 48 01

Other endocrine (C75) 46 01 20 00

Hodgkin disease (C81) 92 02 42 01

Non-Hodgkin lymphoma (C82~85 C96) 1185 23 793 20

Immunoproliferative diseases (C88) 9 00 0 00

Multiple myeloma (C90) 267 05 202 05

Lymphoid leukaemia (C91) 290 06 194 05

Myeloid leukaemia (C92~94) 645 12 555 14

Leukaemia unspecified (C95) 39 01 39 01

Other and unspecified 981 19 819 20 (C26 C39 C48 C76 C80 C97)

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

30 Cancer Research and Treatment 200436(1)

28 Cancer Research and Treatment 200436(1)

Appendix 1 Continued

985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114Presbyterian Medical Center

Pundang Je-Saeng Hospital

Pusan Adventist Hospital

Pusan Medical Center

Pusan National University Hospital

Samsun Hospital

Samsung Medical center

Sansung Cheil Hospital amp Womens Health Care Center

Sejong General Hospital

Seo San Medical Center

Seoul Adventist Hospital

Seoul Municipal Boramae Hospital

Seoul National University Hospital

Seoul Red Cross Hospital

Severance Hospital Yonsei University Medical College

Shin Chun Hospital

Soonchunhyang GuMi Hospital

Soonchunhyang University Cheonan Hospital

Soonchunyang Univ Hospital

St Marys hospital The Catholic University of Korea

St Francisco General Hospital

St Pauls Hospital

Sun General Hospital

Sung Ae Hospital

Taeback Choongang General Hospital

Taegu Catholic University Hospital

Taegu Fatima Hospital

The Catholic University of Korea Kangnam St Marys Hospital

The Catholic University of Korea Taejon St Marys Hospital

The Catholic University of Korea Our Lady of mercy Hospital

The Catholic University of Korea St Vincents Hospital

Uijongbu St Marys Hospital The Catholic University of Korea

Ulsan University Hospital

Wallace Memorial Baptist Hospital

WonJu Christian Hospital Won Ju Clooege of Medicine Yonsei University

WonKwang University Hospital

Yeungnam University Medical Center

Yeungnam University Youngchun Hospital

Yonsei Medical center Yong-Dong Severance Hospital

Young Dong Hospital985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Appendix 2 Marginal frequency of malignant cases by sexgender and ICD-10 grouping in 2001985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114

Male FemaleSite (code) 985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103}}}}}985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

n n 985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Lip (C00) 17 00 11 00

Tongue (C01~02) 209 04 79 02

Mouth (C03~06) 242 05 99 02

Salivary glands (C07~08) 136 03 107 03

Tonsil (C09) 109 02 15 00

Other oropharynx (C10) 46 01 6 00

Nasopharynx (C11) 218 04 81 02

Hypopharynx (C12~13) 239 05 14 00

Pharynx unspecified (C14) 27 01 3 00

Oesophagus (C15) 1416 27 120 03

Stomach (C16) 12356 239 6050 151

Small intestine (C17) 204 04 140 03

Colon (C18) 2620 51 2112 53

Rectum (C19~20) 2814 54 2073 52

Anus (C21) 59 01 62 02

Liver (C22) 8259 160 2596 65

Gallbladder etc(C23~24) 1361 26 1241 31

Pancreas (C25) 1187 23 854 21

Nose sinuses etc(C30~31) 148 03 81 02

Larynx (C32) 920 18 71 02

TrecheaTrachea bronchus and lung (C33~34) 8292 160 2632 65

Other thoracic organs (C37~38) 157 03 89 02

Bone (C40~41) 218 04 191 05

Melanoma of skin (C43) 112 02 111 03

Other skin (C44) 509 10 493 12

Mesothelioma (C45) 27 01 11 00

Kaposi sarcoma (C46) 7 00 6 00

Connective and soft tissue (C47~49) 294 06 251 06

Breast (C50) 36 01 6459 161

Vulva (C51) - - 67 02

Vagina (C52) - - 48 01

Cervix uteri (C53) - - 4054 101

Corpus uteri (C54) - - 739 18

Uterus unspecified (C55) - - 61 02

Ovary (C56) - - 1520 38

Other female genital organs (C57) - - 34 01

Placenta (C58) 0 00 69 02

Penis (C60) 44 01 - -

Prostate (C61) 1466 28 - -

Testis (C62) 133 03 - -

Other male genital organs (C63) 28 01 - -

Kidney (C64) 1011 20 465 12

Renal pelvis (C65) 128 02 29 01

Ureter (C66) 117 02 62 02

Bladder (C67) 1730 33 415 10

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Hai-Rim Shin et alAnnual Report of the KCCR-2001 29

Appendix 2 Continued985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114

Male FemaleSite (code) 985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103}}}}}}}}}985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

n n 985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Other urinary organs (C68) 21 00 24 01

Eye (C69) 51 01 40 01

Brain nervous system (C70~72) 609 12 489 12

Thyroid (C73) 551 11 3305 82

Adrenal gland (C74) 71 01 48 01

Other endocrine (C75) 46 01 20 00

Hodgkin disease (C81) 92 02 42 01

Non-Hodgkin lymphoma (C82~85 C96) 1185 23 793 20

Immunoproliferative diseases (C88) 9 00 0 00

Multiple myeloma (C90) 267 05 202 05

Lymphoid leukaemia (C91) 290 06 194 05

Myeloid leukaemia (C92~94) 645 12 555 14

Leukaemia unspecified (C95) 39 01 39 01

Other and unspecified 981 19 819 20 (C26 C39 C48 C76 C80 C97)

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

30 Cancer Research and Treatment 200436(1)

Appendix 2 Marginal frequency of malignant cases by sexgender and ICD-10 grouping in 2001985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114

Male FemaleSite (code) 985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103}}}}}985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

n n 985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Lip (C00) 17 00 11 00

Tongue (C01~02) 209 04 79 02

Mouth (C03~06) 242 05 99 02

Salivary glands (C07~08) 136 03 107 03

Tonsil (C09) 109 02 15 00

Other oropharynx (C10) 46 01 6 00

Nasopharynx (C11) 218 04 81 02

Hypopharynx (C12~13) 239 05 14 00

Pharynx unspecified (C14) 27 01 3 00

Oesophagus (C15) 1416 27 120 03

Stomach (C16) 12356 239 6050 151

Small intestine (C17) 204 04 140 03

Colon (C18) 2620 51 2112 53

Rectum (C19~20) 2814 54 2073 52

Anus (C21) 59 01 62 02

Liver (C22) 8259 160 2596 65

Gallbladder etc(C23~24) 1361 26 1241 31

Pancreas (C25) 1187 23 854 21

Nose sinuses etc(C30~31) 148 03 81 02

Larynx (C32) 920 18 71 02

TrecheaTrachea bronchus and lung (C33~34) 8292 160 2632 65

Other thoracic organs (C37~38) 157 03 89 02

Bone (C40~41) 218 04 191 05

Melanoma of skin (C43) 112 02 111 03

Other skin (C44) 509 10 493 12

Mesothelioma (C45) 27 01 11 00

Kaposi sarcoma (C46) 7 00 6 00

Connective and soft tissue (C47~49) 294 06 251 06

Breast (C50) 36 01 6459 161

Vulva (C51) - - 67 02

Vagina (C52) - - 48 01

Cervix uteri (C53) - - 4054 101

Corpus uteri (C54) - - 739 18

Uterus unspecified (C55) - - 61 02

Ovary (C56) - - 1520 38

Other female genital organs (C57) - - 34 01

Placenta (C58) 0 00 69 02

Penis (C60) 44 01 - -

Prostate (C61) 1466 28 - -

Testis (C62) 133 03 - -

Other male genital organs (C63) 28 01 - -

Kidney (C64) 1011 20 465 12

Renal pelvis (C65) 128 02 29 01

Ureter (C66) 117 02 62 02

Bladder (C67) 1730 33 415 10

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Hai-Rim Shin et alAnnual Report of the KCCR-2001 29

Appendix 2 Continued985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114

Male FemaleSite (code) 985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103}}}}}}}}}985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

n n 985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Other urinary organs (C68) 21 00 24 01

Eye (C69) 51 01 40 01

Brain nervous system (C70~72) 609 12 489 12

Thyroid (C73) 551 11 3305 82

Adrenal gland (C74) 71 01 48 01

Other endocrine (C75) 46 01 20 00

Hodgkin disease (C81) 92 02 42 01

Non-Hodgkin lymphoma (C82~85 C96) 1185 23 793 20

Immunoproliferative diseases (C88) 9 00 0 00

Multiple myeloma (C90) 267 05 202 05

Lymphoid leukaemia (C91) 290 06 194 05

Myeloid leukaemia (C92~94) 645 12 555 14

Leukaemia unspecified (C95) 39 01 39 01

Other and unspecified 981 19 819 20 (C26 C39 C48 C76 C80 C97)

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

30 Cancer Research and Treatment 200436(1)

Appendix 2 Continued985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114985114

Male FemaleSite (code) 985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103}}}}}}}}}985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

n n 985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

Other urinary organs (C68) 21 00 24 01

Eye (C69) 51 01 40 01

Brain nervous system (C70~72) 609 12 489 12

Thyroid (C73) 551 11 3305 82

Adrenal gland (C74) 71 01 48 01

Other endocrine (C75) 46 01 20 00

Hodgkin disease (C81) 92 02 42 01

Non-Hodgkin lymphoma (C82~85 C96) 1185 23 793 20

Immunoproliferative diseases (C88) 9 00 0 00

Multiple myeloma (C90) 267 05 202 05

Lymphoid leukaemia (C91) 290 06 194 05

Myeloid leukaemia (C92~94) 645 12 555 14

Leukaemia unspecified (C95) 39 01 39 01

Other and unspecified 981 19 819 20 (C26 C39 C48 C76 C80 C97)

985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103985103

30 Cancer Research and Treatment 200436(1)