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Answer• 1.Alder- reilly anamoly.• 2. plasma cells• 3. Burkett lymphoma “starlight”• 4. Chediak-Steinbrinck –Higashi Anomaly• 5. Reed sternberg cells- Hogdkin lymphoma• 6. Smudge cells –CLL/SLL• 7. ALL• 8. AML• 9. May-Hegglin Anomaly, associated with giant platelets• 10. hairy Cell lymphoma-B cell• 11. Sezary- t cell• 12. Dsyelomyeloiesis• 13. Pelger-Huet Bodies• 14. Nuclear extrusion anomaly• 15. Dohle bodies• 16.Promyelocyte• 17. Band• 18. Myelocyte• 19.metamyelocyte• 20. Auer rods
Alder-Reilly Anomaly1.Cytoplasmic inherited
abnormalities of neutrophils.
2. Seen in inheritedHunter’s or Hurler’s syndromes.3. Heavy granulation.4. Also seen in mucopolysaccharide storage disease.5. Caused by an inherited autosomal recessive trait.
May-Hegglin Anomaly
1. Rare, autosomal dominant, qualitative leukocyte abnormality.
2. Appears as Dohle-like inclusions.
3. Associated with giant platelets , thrombocytopenia , and slight bleeding tendency.
4. Cytoplasmic inclusions in May-Hegglin anomaly are PAS negative.
5. Inclusion found in eosinophils, basophils, monocytes, and neutrophils.
6. Cytoplasmic inclusions results from structural RNA.
Chediak-Steinbrinck –Higashi Anomaly
1. Rare, autosomal recessive disorder that results in qualitative abnormalities in all types of leucocytes.
2. Giant , coarse , irregular , peroxidase positive lysosome granules are found in the cytoplasm of granulocytes and monocytes.
3. Patients demonstrate abnormal pigmentation ,pancytopenia, neuropathies, and recurrent infections.