EXPERTS IN TREATMENT

ANTIMICROBIAL DRUGS

OF SYSTEMIC ACTION

WWWBIOFARMKHARKIVCOM

ANTIMICROBIAL DRUGS

OF SYSTEMIC ACTION

AdministrationTreatment of colibacillosis, salmonellosis, necrotic enteritis, streptococcosis, hemophillosis, mycoplasmosis and other infectious diseases caused by enrofloxacin– and trimethoprim-sensitive microorganisms in poultry.DosageAdminister orally with drinking water in a dose of 0.5-1 ml of the drug per 1 l of drinking water for 3-5 days.ContraindicationsHypersensitivity to enrofloxacin and trimethoprim. Do not administer to hens laying eggs for human consumption and pullets in 2 weeks prior to commencement

of the laying period. Do not administer in combination with non-steroid anti-inflammatory agents, antibiotics of the macrolides group, tetracycline and chloramphenicol.Withdrawal period is 11 days.PackagingCardboard boxes with 10 plastic vials of 10 ml each and plastic vials of 1 000 ml.StorageStore in a dry, dark place out of the reach of children at 5-30°С.Shelf life3 years. 24 hours after dissolution in drinking water.

AdministrationTreatment of diseases of digestive tract, respiratory organs and urinary system as well as skin and soft tissues caused by enrofloxacin– and trimethoprim-sensitive microorganisms in cattle and swine.DosageCattle. Administer subcutaneously in a dose of 2.5 ml of the drug per 100 kg body weight once daily for 3-5 days. In salmonellosis and diseases of respiratory organs administer 5 ml of the drug per 100 kg body weight once daily for 5 days.Swine. Administer intramuscularly in a dose of 0.25 ml of the drug per 10 kg body weight once daily for 3 days. In salmonellosis and infections of respiratory organs administer 0.5 ml of the drug per 10 kg body weight once daily for 5 days.

ContraindicationsHypersensitivity to enrofloxacin and trimethoprim. Do not administer to pregnant swine. Do not administer Triflon 100 in combination with tetracycline, chloramphenicol, theophylline and non-steroidal anti-inflammatory agents.

Withdrawal period for meat is 14 days, for milk is 7 days.

PackagingGlass vials of 100 ml sealed with rubber stoppers and aluminum caps in cardboard boxes.

StorageStore in a dry, dark place out of the reach of children at 5-30°С.Shelf life3 years.

AdministrationTreatment of mycoplasmosis, ornithobacteriosis, colibacillosis, salmonellosis, necrotic enteritis, streptococcosis as well as other diseases of digestive tract and respiratory organs caused by enrofloxacin-, tilmicosin– and timetoprim-sensitive microorganisms in poultry.

DosageAdminister orally with drinking water in a dose of 1-2 ml of the drug per 1 l of drinking water for 3-5 days. In mycoplasmosis and ornithobacteriosis administer 2 ml per 1 l of drinking water for the first 3 days of life. It is recommended that the treatment is repeated in 20-22 days in a dose of 1-2 ml per 1 l of drinking water during 3 days.

ContraindicationsDo not administer to poultry with hypersensitivity to the drug components. Do not administer to hens laying eggs for human consumption. Do not administer in combination with antibiotic of the tetracycline, chloramphenicol and lincomycine group. Do not administer to poultry with kidney and/or liver injuries.Withdrawal period is 12 days.PackagingCardboard boxes with 10 vials of 10 ml each, plastic vials of 1 l.StorageStore in a dry, dark place out of the reach of children at 5-30°С.Shelf life2 years.24 hours after dissolution in water.

Solution for oral administration

Solution for injections

Solution for oral administration

Composition1 ml of the drug contains:active ingredients: enrofloxacin – 100 mg; trimethoprim – 50 mg;excipient – purified water.

Composition1 ml of the drug contains:active ingredients: enrofloxacin – 100 mg; trimethoprim – 50 mg;excipient – water for injections.

Composition1 ml of the drug contains:active ingredients: tilmicosin – 50 mg; enrofloxacin – 50 mg; trimethoprim – 25 mg;excipient – purified water.

TRIFLON

TRIFLON 100

TRIMICOSIN

EXPERTS IN TREATMENT

AdministrationTreatment of mycoplasmosis, ornithobacteriosis, colibacillosis, salmonellosis, necrotic enteritis, streptococcosis as well as other diseases of digestive tract and respiratory organs caused by enrofloxacin-, tilmicosin- and timetoprim-sensitive microorganisms in poultry.

DosageAdminister orally with drinking water in a dose of 0.5-1 kg of the drug per 1 t of drinking water during the first 3-5 days of life. It is recommended that the treatment be repeated in 20 to 22 days in a dose of 0.5-1 kg of the drug per 1 t of drinking water for 3 days.

ContraindicationsDo not administer to poultry with hypersensitivity to the drug components. Do not administer to hens laying eggs for human consumption. Do not administer in combination with antibiotic of the tetracycline, chloramphenicol and lincomycine group.Withdrawal period is 12 days.PackagingBags of 1 000 g film or foil materials.StorageStore in a dry, dark place out of the reach of children at 5-30°С.Shelf life2 years.24 hours after dissolution in water.

AdministrationCattle: treatment of animals against acute mastitis, escherichiosis, respiratory diseases caused by Pasteurella multocida, P. haemolytica and other cefquinome-sensitive microorganisms as well as panaritium, hoof sole ulcer, purulent pododermatitis, septicemia, bacterial interdigital dermatitis and necrobacillosis.Swine: treatment of animals against MMA syndrome, meningitis, arthritis, dermatitis as well as diseases of respiratory organs caused by Pasteurella multocida, Haemophillus parasuis, Actinobacillus pleuropneumoniae, Streptococcus suis and other cefquinome-sensitive bacteria.

ContraindicationsDo not administer to animals sensitive to the drug and other β-lactam antibiotics. Do not prescribe in combination with bacteriostatics.Withdrawal period for meat of swine is 4 days, for meat of cattle is 8 days and for milk is 3 days.PackagingGlass vials of 100 ml.StorageStore in a dark place at 2-30°С.Shelf life2 years.

AdministrationTreatment of animals against diseases caused by amoxicillin– and gentamicin-sensitive microorganisms:– swine: pneumonia, diarrhea, enteritis, colibacteriosis, metritis, mastitis;– sheep and goats: pneumonia, diarrhea, enteritis, pasteurellosis, colibacteriosis;– cattle: pneumonia, diarrhea, enteritis, mastitis, metritis, superficial abscess;– horses: pneumonia, diarrhea, enteritis, superficial abscess, genitourinary and limb diseases.DosageAdminister the drug intramuscularly in a dose of 1 ml per 10 kg body weight of an animal once daily for 3-5 days. Shake the vial thoroughly before use.ContraindicationsDo not prescribe to animals with individual

hypersensitivity to amoxicillin and gentamicin. Do not use in non-target animals. Do not administer to rabbits, hamsters and other small herbivorous animals. Do not administer to animals with kidney function, hearing organs and vestibular system disorders.Withdrawal period for meat is 30 days, for milk is 3 days.PackagingGlass vials of 100 ml with rubber stoppers and aluminum caps.StorageStore in a dry, dark place out of the reach of children at 15-30°С.Shelf life2 years.28 days following the first sampling from the vial in case of storage in a dark place at 2-8°С.

Water-soluble powder for oral administration

Suspension for injections

Suspension for injection

Composition1 g of the drug contains:active ingredients: tilmicosin phosphate – 100 mg; enrofloxacin – 100 mg; trimethoprim – 50 mg;excipient – glucose.

Composition1 ml of the drug contains:active ingredient: cefquinome sulfate – 29.64 mg;excipients – colza oil, propylparahydroxybenzoate, methylparahydroxybenzoate.

Composition1 ml of the drug contains:active ingredients: amoxicillin (amoxicillin trihydrate) – 150 mg;gentamicin (gentamicin sulfate) – 40 mg;excipient – vegetable oil.

TRIMICOSIN М

CEBACTAL

AMOXILEK

DosageAnimal species Indications Daily drug dose

(per 10 kg body weight)Duration of treatment

Cattle Diseases of respiratory organs, interdigital necrobacillosis or dermatitis

0.4 ml 3-5 days

Acute mastitis 0.4 ml 2 daysEscherichiosis (colibacillosis) in calves 0.8 ml 3-5 days

Swine Diseases of respiratory organs 0.8 ml 3 daysMMA syndrome 0.8 ml 2 daysMeningitis, arthritis, dermatitis 0.8 ml 5 days

ANTIMICROBIAL DRUGS

OF SYSTEMIC ACTION

AdministrationTreatment of diseases of respiratory organs, urinary system and digestive tract caused by trimethoprim – and colistin-sensitive microorganisms in calves, goats and lambs of up to 3 months of age, swine, rabbits, chickens and broiler chickens.DosageAdminister orally with drinking water or liquid feed in the following doses:– calves, goatlings and lambs of up to 3 months of age, swine, rabbits: 2-2.5 g of the drug per 10 kg body weight twice daily (maximum 30 g of the drug per animal daily) for 3 days;– chickens and broiler chickens: 1-2.5 g of the drug per 1 l of drinking water (young poultry – maximum 1 g of the drug per 1 l of drinking water in the beginning of treatment) for 3 days. The drug solution must be the only source of drinking water throughout the whole treatment period!

ContraindicationsDo not administer to animals with hypersensitivity to colistin and trimethoprim as well as to animals with liver and kidney injuries. Do not administer in combination with aminoglycosides (gentamicin, neomycin), muscle relaxant and anesthetics. Resistance of strains of pathogenic bacteria to colistin and/or trimethoprim belongs to contraindications for administration. Do not administer to hens laying eggs for human consumption as well as ruminants with functionally developed proventriculi.Withdrawal period is 7 days.PackagingBags of 1 000 g of film or foil materials.StorageStore in a dry, dark place out of the reach of children at 5-30°С.Shelf life2 years.24 hours after dissolution in drinking water.

AdministrationTreatment of diseases of respiratory organs caused by tilmicosin-sensitive microorganisms in chickens, calves (of up to 6 months of age), piglets (of up to 3 months of age). DosageAdminister orally with drinking water or milk substitute in the following doses:– chickens: 300 ml of the drug per 1 t of drinking water for the first 3 days of life. It is recommended that the administration be repeated on the 20th-22nd day of life (the duration and dose being the same);– piglets (of up to 3 months of age): 80 ml of the drug per 100 l of drinking water for 5 days;– calves (of up to 6 months of age): 1 ml of the drug per 20 kg body weight twice daily for 3-5 days.

ContraindicationsDo not administer to animals with hypersensitivity to tilmicosin. Do not administer to hens laying eggs for human consumption. Do not administer in combination with injections of macrolides. Do not prescribe to cows with functionally developed proventriculi. Do not administer with feed containing bentonites.Withdrawal period for meat of piglets is 14 days, for meat of chickens is 7 days, for meat of calves is 36 days.PackagingPlastic vials of 1 000 ml.StorageStore in a dry, dark place out of the reach of children at 5-30°С.Shelf life2 years.24 hours after dissolution.

AdministrationTreatment of calves (of up to 3 months of age), swine, sheep, goats, dogs, cats, poultry (broiler chickens, turkeys) against diseases of digestive tract and respiratory organs caused by lincomycin– and spectinomycin-sensitive microorganisms.DosageAdminister intramuscularly in the neck area in the following doses:– swine: 1 ml of the drug per 10 kg body weight once daily for 3-7 days;– calves of up to 3 months of age: 1 ml of the drug per 10 kg body weight once daily for 2-4 days;– sheep, goats: 1 ml of the drug per 10 kg body weight once daily for 3 days;– dogs, cats: 1 ml of the drug per 5 kg body weight once daily for 3-5 days (maximum treatment period – 21 days).Administer subcutaneously in the following doses:– broiler chickens, turkeys: 1 ml of the drug per 2.5 kg body weight once daily for 3 days.

ContraindicationsDo not administer to animals with hypersensitivity to lincomycin and spectinomycin. Do not administer to animals with blood or liver disorders. Do not administer to horses, rabbits, chinchillas as well as to hens laying eggs for human consumption. Do not administer Spelimix in combination with penicillin, quinolones, cephalosporins and erythromycin.Withdrawal period for meat of poultry is 7 days, for meat of others is 14 days, for milk is 3 days.PackagingGlass vials of 100 ml sealed with rubber stoppers and aluminum caps.StorageStore in a dry, dark place out of the reach of children at 15-25°С.Do not freeze!Shelf life2 years.48 hours after the initial opening (sampling) provided it is stored at 2-8°С.

Water-soluble powder for oral administration

Solution for oral administration

Solution for injections

Composition1 g of the drug contains:active ingredients: colistin sulfate – 1 200 000 IU; trimethoprim – 50 mg;excipient – glucose.

Composition1ml of the drug contains:active ingredient: tilmicosin base – 250 mg;excipient – propylene glycol.

Composition1 ml of the drug contains:active ingredients: lincomycin (lincomycin hydrochloride) – 50 mg; spectinomycin (spectinomycin sulfate) – 100 mg;excipients – benzyl alcohol, water for injections.

TRIMECOL

TILMICOL

SPELIMIX

EXPERTS IN TREATMENT

AdministrationTreatment of hens (broiler chickens, breeding hens, pullets) ) and swine against enzootic pneumonia, salmonellosis, dysentery, MMA (mastitis-metritis-agalactia) syndrome, necrotic enteritis, colibacillosis, mycoplasmosis and other diseases of digestive tract and respiratory organs caused by lincomycin– and spectinomycin-sensitive microorganisms.DosageAdminister orally with feed individually to every animal or by group method in the following doses:– 2 kg of Spelimix 44 per 1 t of feed for 5-7 days.It is recommended that the drug be mixed up with 3-10% of total feed quantity first and then the obtained blend be mixed with the rest of the feed.

ContraindicationsDo not administer to animals with hypersensitivity to lincomycin and spectinomycin as well as to hens laying eggs for human consumption. Do not administer in combination with penicillin, cephalosporins and macrolides.Withdrawal period for meat of swine is 3 days, for meat of poultry is 2 days.PackagingBags of film or foil materials of 1 000 g and paper bags of 25 kg.StorageStore in a dry, dark place out of the reach of children at 0-30°С.Shelf life1 year.

AdministrationTreatment of poultry (broilers, breeders, pullets) and swine against enzootic pneumonia, salmonellosis, dysentery, MMA (mastitis-metritis-agalactia) syndrome, necrotic enteritis, colibacillosis, mycoplasmosis and other diseases of digestive tract and respiratory organs caused by lincomycin– and spectinomycin-sensitive microorganisms.DosageAdminister orally with drinking water in the following doses:– piglets: 10 mg of active ingredients per 1 kg body weight daily (1.5 g of the powder per 100 kg body weight) or 150 g of the drug per 1,5 t of drinking water. Treatment period: 4-7 days;– broilers, breeders, pullets: 150 g of the drug per 150-200 l of drinking water for 5-7 days.The solution of the drug must be the only source of drinking water throughout the whole treatment period!

ContraindicationsDo not administer to animals with hypersensitivity to lincomycin and spectinomycin as well as to hens laying eggs for human consumption. Do not prescribe to pregnant or lactating sows. Do not administer in combination with penicillin, cephalosporins and macrolides.Withdrawal period for meat of swine is 3 days, for meat of poultry is 2 days.PackagingBags of film or foil materials of 150 g.StorageStore in a dry, dark place out of the reach of children at 0-30°С.Shelf life2 years.24 hours after dissolution in drinking water.

AdministrationTreatment of swine against enzootic pneumonia, salmonellosis, dysentery, actinobacillary pleuropneumonia, eperythzoonosis, MMA (mastitis-metritis-agalactia) syndrome, necrotic enteritis, colibacillosis, mycoplasmosis and other diseases of digestive tract and respiratory organs caused by lincomycin– and spectinomycin-sensitive microorganisms.DosageAdminister orally with feed individually or by group method in a dose of 0.5-1 kg of the drug per 1 t of feed for 5-7 days.If used with feed, it is necessary to mix the drug with the feed thoroughly. It is recommended that the drug be mixed with 3-10% of total feed quantity first and then blend the obtained mixture with the rest of the feed.ContraindicationsDo not administer to animals with

hypersensitivity to lincomycin and spectinomycin. Do not administer to rabbits, horses, cattle and laying hens. Do not administer to pregnant and lactating animals. Do not administer to animals with liver and kidney disorders. Do not administer in combination with erythromycin, antibiotics of the penicillin group, cephalosporins and fluoroquinolones as well as thiamfenicol and chloramfenicol.Withdrawal period is 14 days.PackagingBags of film or foil materials of 1 000 g andpaper bags of 25 kg.StorageStore in a dark, damp-proof place out of the reach of children at 0-30°С.Shelf life1 year.3 months after being mixed with feed.

Powder for oral administration

Water-soluble powder for oral administration

Powder for oral administration

Composition1 g of the drug contains:active ingredients: lincomycin hydrochloride – 22 mg; spectinomycin sulfate – 22 mg;excipient – semolina.

Composition150 g of the drug contains:active ingredients: lincomycin hydrochloride – 33.3 g; spectinomycin sulfate – 66.7 g;excipient – lactose.

Composition1 g of the drug contains:active ingredients: florfenicol – 40 mg; lincomycin (lincomycin hydrochloride) – 44 mg; spectinomycin (spectinomycin sulfate) – 44 mg;excipient – wheat groats

SPELIMIX 44

SPELIMIX 100

SPELIMIX FORTE

ANTIMICROBIAL DRUGS

OF SYSTEMIC ACTION

AdministrationTreatment of diseases of respiratory organs, digestive organs and urinary system caused by sulfametoxazol– and trimethoprim-sensitive microorganisms in cattle, sheep, goats, swine and rabbits.DosageThe drug is administered intramuscularly in the following doses:– cattle (adult), sows: 1 ml of the drug per 20 kg body weight once daily for 3-5 days;– calves, sheep, goats, piglets: 1 ml of the drug per 10 kg body weight once daily for 3-5 days;– rabbits: 0.1 ml of the drug per 1 kg body weight once or twice with an interval of 1-1.5 days.ContraindicationsDo not prescribe to animals with individual hypersensitivity to trimethoprim and sulfametoxazol. Do not administer in combination with drugs, which cause sulfur removal (sodium sulfate), aminoglycosides

(gentamicin, neomycin, streptomycin), as well as muscle relaxant and anesthetics as this may cause paralysis of respiratory muscles. Do not administer to animals with kidney and liver disorders as well as to animals with essential changes in hematological indices (in case of dyscrasia). Be cautious when administering the drug to goats as they are hypersensitive to sulfanilamides.Do not use Novocain solution for dissolution.Withdrawal period for meat is 12 days, for milk is 4 days.PackagingGlass vials of 100 ml sealed with rubber stoppers and aluminum caps.StorageStore in a dry, dark place out of the reach of children at 5-30°С.Shelf life2 years.48 hours after the initial opening (sampling) provided it is stored at 2-8°С.

AdministrationTreatment of calves, goatlings and lambs of up to 3 months of age, in swine and broiler chickens of gastrointestinal diseases caused by amoxicillin– and colistin-sensitive microorganisms.

DosageOrally with drinking water or feed in the following doses:– calves, goatlings and lambs of up to 3 months of age: 5 g per 100 kg body weight twice daily for 3-5 days with feed or drinking water;– broiler chickens, swine: 1 kg per 1 t of drinking water for 3-5 days.In case of administration with drinking water the drug solution shall be the only source of drinking water throughout the whole treatment period!

ContraindicationsDo not prescribe to animals with hypersensitivity to colistin and amoxicillin as well as with kidney injuries. Do not use concurrently with chloramphenicol, tetracyclines and sulfanilamides. Do not administer to ruminants with functionally developed proventriculi and hens laying eggs for human consumption. Withdrawal period is 8 days.PackagingPackages of film or foil materials of 1 000 g.StorageStore in a dry dark place out of the reach of children at 5-30°С.Shelf life2 years.8 hours following dissolution in water.

AdministrationTreatment of poultry (broiler chickens, breeding hens, pullets), piglets and calves (of up to 3 months of age) against diseases of respiratory organs and digestive tract caused by doxycycline– and tylosin-sensitive microorganisms.DosageAdminister orally with drinking water in the following doses:– calves (up to 3 months of age): 5 g per 100 kg body weight twice daily for 3-5 days;– piglets (up to 3 months of age), poultry (broiler chickens, breeding hens, pullets): 1 kg per 1 t of drinking water for 3-5 days.ContraindicationsDo not administer to animals with hypersensitivity to doxycycline and tylosin, to animals with liver and kidney injuries. Do

not prescribe in combination with penicillins, cephalosporins, quinolones and cycloserines. Do not administer to ruminants with functionally developed proventriculi and hens laying eggs for human consumption.

Withdrawal period for meat of cattle is 14 days, for meat of piglets is 8, for meat of poultry is 7 days.

PackagingPackages of film or foil materials of 1 000 g.

StorageStore in a dark dry place out of the reach of children at 5-30°С.

Shelf life2 years.24 hours after dissolution in water.

Solution for injections

Water-soluble powder for oral administration

Water-soluble powder for oral administration

Composition1 ml of the drug contains:active ingredients: sulfametoxazol – 200 mg; trimethoprim – 40 mg;excipient – propylene glycol.

Composition1 g of the drug contains:active ingredients: colistin sulfate – 1 200 000 IU; amoxicillin trihydrate – 200 mg;excipient – glucose.

Composition1 g of the drug contains:active ingredients: doxycycline (in form of doxycycline hydrochloride) – 100 mg; tylosin (in form of tylosin tartrate) – 100 mg; ascorbic acid – 100 mg;excipient – glucose.

SUPRIM 240

AMPICOL

DOXYTIL

EXPERTS IN TREATMENT

AdministrationSwine. Treatment of dysentery, atrophic rhinitis, enzootic pneumonia, actinobacillosis pleuropneumonia, hemophilosis, intestinal spirochetosis, salmonellosis, colibacteriosis, necrotic enteritis, caused by microorganisms sensitive to tiamulin and doxycycline.Hens (chickens, broiler chickens) and turkeys. Treatment of diseases of digestive tract and respiratory organs caused by tiamulin – and doxycycline-sensitive microorganisms (Mycoplasma gallisepticum, Mycoplasma synoviae and Mycoplasma meleagridis).DosageAdminister orally with feed or drinking water in the following doses:– swine: 0.5-1 kg of the drug per 1 t of feed or 0.25-0.5 kg of the drug per 1 t of drinking water daily for 7 days;– poultry (chickens, broiler chickens) and turkeys: 0.25-0.5 kg of the drug per 1 t of feed or 0.125-0.25 kg of the drug per 1 t of drinking water daily for 7 days. ContraindicationsDo not administer to animals with hypersensitivity to tetracyclines and tiamulin as well as to animals with kidney and liver disorders. Avoid administration of

drugs containing monensin, maduramycin, narasin, lasalocid or salinomycin at least in 7 days prior to, during and in 7 days following administration of Tiakur as this may cause deterioration in health condition or even death. Do not prescribe in combination with penicillins, cephalosporins, quinolones, erythromycin, sulfonamides, chloramphenicol and chlorpromazine as well as with drugs containing cations of magnesium, calcium, aluminum, as the latter are bound to doxycycline and prevent its absorption.Do not administer the drug to hens and turkeys laying eggs for human consumption. Do not administer the drug to pregnant or lactating animals.Withdrawal period is 10 days.PackagingBags of 1 000 g film or foil materials.StorageStore in a dry, dark place out of the reach of children at 5-30°С.Shelf life18 months. 24 hours after dissolution in drinking water.7 days after being mixed with feed.

AdministrationTreatment of keratoconjuctivitis, colibacillosis, salmonellosis, pasteurellosis, staphilococcosis, gastroentherocolitis, mastitis, dysentery, atrophic rhinitis, enzootic pneumonia, actinobacillary pneumonia, haemophillosis, intestinal spirochetosis, necrotic enteritis in swine, cattle, sheep and goats. The drug is also effective in treatment of diseases of respiratory organs, urinary system, digestive tract, skin, musculoskeletal system, of post-surgical, wound and postpartum complications caused by doxycycline– and tiamulin-sensitive microorganisms.DosageAdminister intramuscularly for 2-3 days in the following doses:– cattle, sheep, goats, swine: 1-1.5 ml per 10 kg body weight.Administer not more than 10 ml into a single site to adult cattle, not more than 2.5 ml – to calves, sheep and goats, not more than 5ml to swine. In case the required dose exceeds the acceptable dose – divide it and make injections to several sites.

ContraindicationsDo not administer to animals with hypersensitivity to tetracyclines and tiamulin as well as to animals with kidney and liver disorders. Avoid administration of drugs containing ionophoric antibiotics such as monensin, maduramycin, narasin, lasalocid or salinomycin during 7 days prior to, and during 7 days following administration of Tiakur 250. Do not use the drug in combination with penicillins, cephalosporins.Withdrawal period is 21 days.PackagingGlass vials of 100 ml sealed with rubber stoppers and aluminum caps.StorageStore in a dry, dark place out of the reach of children at 5-30°С.Shelf life2 years. 28 hours after the initial opening (sampling) provided it is stored at 5-30°С in the original packaging.

AdministrationTreatment of lawsoniosis, enzootic pneumonia, actinobacillary pleuropneumonia, salmonellosis, dysentery, MMA (mastitis-metritis-agalactia) syndrome, eperythrozoonosis, necrotic enteritis, colibacillosis, mycoplasmosis and other diseases of digestive tract and breathing organs caused by tiamulin-, lincomycin– and spectinomycin-sensitive microorganisms in swine.DosageAdminister orally with feed individually or by group method in a dose of 0.5-1 kg of Tiamix per 1 t of feed for 5-7 days or with drinking water in a dose of 0.5-1 kg of Tiamix per 1 t of drinking water for 5-7 days.If administered with feed, mix the drug with the feed thoroughly. It is recommended that the drug be used with 3-10% of total feed quantity first and then the obtained mixture be mixed with the rest of the feed.If administered with drinking water, the medicated solution must be the only source of drinking water throughout the whole treatment period.

ContraindicationsDo not administer to animals with hypersensitivity to tiamulin, lincomycin and spectinomycin. Do not administer to rabbits, horses, cattle and laying hens. Do not administer to pregnant and lactating animals.Avoid administration of drugs containing monensin, maduramycin, narasin, lasalocid or salinomycin at least in 7 days prior to, during and in 7 days following administration of Tiamix as this may cause deterioration in health condition or even death.Withdrawal period is 7 days.PackagingBags of 1000 g film or foil materials.StorageStore in a dark, damp-proof place out of the reach of children at 0-30°С.Shelf life2 years. 3 months after being mixed with feed. 24 hours after dissolution in drinking water.

Water-soluble powder for oral administration

Solution for injections

Water-soluble powder for oral administration

Composition1 g of the drug contains:active ingredients: doxycycline hyclate – 200 mg; tiamulin (tiamulin hydrogen fumarate) – 66 mg;excipient – glucose.

Composition1 ml of the drug contains:active ingredients: doxycycline hyclate – 150 mg; tiamulin (tiamulin hydrogen fumarate) – 100 mg;excipients – 2-pyrrolidone, water for injections.

Composition1 g of the drug contains:active ingredients: tiamulin (as hydrogen fumarate) – 225 mg; lincomycin (as lincomycin hydrochloride) – 44 mg; spectinomycin (spectinomycin sulfate) – 44 mg;excipient – dextrose.

TIAKUR

TIAKUR 250

TIAMIX

ANTIMICROBIAL DRUGS

OF SYSTEMIC ACTION

AdministrationSwine: treatment of animals against pleuropneumonia, atrophic rhinitis, Glasser’s disease, infectious coryzae, mycoplasmosis and other diseases caused by florfenicol-sensitive microorganisms (Actinobacillus pleuropneumoniae, Pasteurella multocida, Bordetella bronchiseptica, Haemophilus parasuis, Pasteurella multocida, Bordetella bronchiseptica). Poultry (broiler chickens, breeding hens, pullets): colisepticemia, pasteurellosis, mycoplasmosis as well as diseases of respiratory organs and digestive tract caused by florfenicol-sensitive microorganisms.DosageAdminister orally with drinking water in the following doses:– swine: 3.75-5 ml of the drug per 100 kg body weight (1.5-2 mf of florfenicol per 1 kg body weight) daily. Duration of treatment – 7 days;– poultry (broiler chickens, breeding hens,

pullets): 50 ml of the drug per 100 kg body weight (20 mg of florfenicol per 1 kg body weight) daily. Duration of treatment: 3-5 days.ContraindicationsDo not administer to animals sensitive to florfenicol. Do not administer to hens laying eggs for human consumption. Do not use in combination with thiamphenicol and chloramphenicol.Withdrawal period is 2 days.PackagingCardboard boxes with 10 vials of 10 ml each, plastic vials of 1 l.StorageStore in a dry, dark, damp-proof place out of the reach of children at 5-30°С.Shelf life2 years. 24 hours after dissolution in water.

AdministrationCattle. Treatment of animals against interdigital necrobacillosis, keratoconjuctivitis as well as diseases of respiratory organs caused by florfenicol-sensitive microorganisms.Swine. Treatment of animals against diseases of respiratory organs caused by florfenicol-sensitive microorganisms. DosageAdminister in the following doses:– swine: 15 mg of florfenicol per 1 kg body weight intramuscularly (0.5 ml of the drug per 10 kg body weight). Repeat injection in 48 hours;– cattle: 20 mg of florfenicol per 1 kg body weight intramuscularly (1 ml of the drug per 15 kg body weight) twice with an interval of 48 hours or 40 mg of florfenicol per 1 kg body weight subcutaneously (2 ml of the drug per 15 kg body weight) once.Administer maximum 10 ml of the drug per single injection site.

ContraindicationsDo not administer to animals sensitive to florfenicol. Do not administer to pregnant and lactating animals, stud bulls and breeding boars. Do not use in combination with antibiotics of the penicillin group, cephalosporins and fluoroquinolones as well as thiamfenicol and chloramfenicol.Withdrawal period for meat of swine is 14 days, for meat of cattle in case of intramuscular administration is 30 days, for meat of cattle in case of subcutaneous administration is 44 days.PackagingGlass vials of 100 ml sealed with rubber stoppers and aluminum caps.StorageStore in a dark place out of the reach of children at 5-30°С. Do not freeze!Shelf life2 years.48 hours after initial opening (sampling) if stored a 2-8°С.

AdministrationSwine. Treatment of animals against pleuropneumonia (Actinobacillus pleuropneumoniae), atrophic rinitis (Pasteurella multocida, Bordetella bronchiseptica), hemophilic polyserositis (Haemophilus parasuis) as well as other diseases of respiratory organs caused by florfenicol-sensitive microorganisms.Fish (carps, salmons). Treatment of fish against aeromonosis (furunculosis, red spot disease, hemorrhagic septicemia), pasteurellosis, enterosepsis, vibriosis, pseudomonosis, streptococcosis caused by florfenicol-sensitive microorganisms.DosageAdminister orally with feed in the following doses:– swine: 1.25 g of the drug per 10 kg body weight daily (5 mg of florfenicol per 1 kg body weight daily). Duration of treatment – 7 days;– fish (carps, salmons): 10 mg of florfenicol per 1 kg of fish daily (25 g of the drug per 100 kg of fish). Duration of treatment – 10 days. Divide

the daily dose in two feedings for small-size and juvenile fish. Recommended norm of ready medicated feed – 0.5-3% of total fish weight.ContraindicationsDo not administer to animals sensitive to florfenicol. Do not administer to pregnant and lactating animals and breeding boars. Do not feed the drug to fish if water temperature is below 5°C. Do not use in combination with antibiotics of the penicillin group, cephalosporins and fluoroquinolones as well as thiamfenicol and chloramfenicol.Withdrawal period for meat of swine is 1 day, for meat of fish is 16 days (if water temperature is 5-10°C) and 8 days (if water temperature is above 10°C).PackagingPackages of film or foil materials of 1000 g.StorageStore in a dark place out of the reach of children at 5-30°С.Shelf life2 years.

Solution for oral administration

Solution for injections

Powder for oral administration

Composition1 ml of the drug contains:active ingredient: florfenicol – 40 mg;excipient – PEG-400.

Composition1 ml of the drug contains:active ingredient: florfenicol – 300 mg;excipients – propylene glycol, PEG-400.

Composition1 kg of the drug contains:active ingredient – florfenicol – 40 g;excipient – semolina.

FLOSAN 4%

FLOSAN 30%

FLOSAN

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