144
“NOW What’re We S upposed to Do?” Evidence-Based Practices for Medication-Assisted Treatment of Substance Use Disorders Michael G Bricker MS, CADC-2, NCAC-II, LPC July 26 th 2017

“NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

  • Upload
    others

  • View
    1

  • Download
    0

Embed Size (px)

Citation preview

Page 1: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

“NOW What’re We Supposed to Do?”

Evidence-Based Practices for Medication-Assisted Treatment of

Substance Use DisordersMichael G Bricker MS, CADC-2, NCAC-II, LPC

July 26th 2017

Page 2: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

Thomas Durham, PhD

Director of Training

NAADAC, the Association for Addiction Professionals

www.naadac.org

[email protected]

Page 3: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

Produced ByNAADAC, the Association for Addiction Professionals

www.naadac.org/webinars

Page 4: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

www.naadac.org/webinars

Page 5: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

www.naadac.org/evidence-based-MAT-practices-webinar

Page 6: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

Cost to Watch:Free

CE Hours Available:2 CEs

CE Certificate for NAADAC Members:Free

CE Certificate for Non-members:$25

To obtain a CE Certificate for the time you spent watching this webinar:

1. Watch and listen to this entire webinar.

2. Pass the online CE quiz, which is posted at

www.naadac.org/evidence-based-MAT-practices-webinar

3. If applicable, submit payment for CE certificate or join NAADAC.

4. A CE certificate will be emailed to you within 21 days of submitting the quiz.

CE Certificate

Page 7: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

Using GoToWebinar – (Live Participants Only)

Control Panel

Asking Questions

Audio (phone preferred)

Polling Questions

Page 8: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

Webinar PresenterMichael G Bricker

MS, CADC-II, NCAC-II, LPCBehavioral Health ClinicianAdult SUD Treatment Mgr.

Klamath Falls, [email protected]

Page 9: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

Webinar Learning Objectives

Articulate the philosophical dialectic and practical consider-ations between "abstinence-based" and "medication-assisted" treatment modalities.

Identify the FDA/DEA-approved and experimental medications for assisting patients in recovery from alcohol, opioid and stimulant use disorders.

Become familiar with evidence based practices either designed for or adaptable for treating patients in recovery from alcohol, opioid and stimulant use disorders.

1 32

Page 10: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

The Scope of the Problem

Heroin Use Trends: 2002-2013

SAMHSA - NSDUH 2014.

Page 11: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment
Page 12: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment
Page 13: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

ASAM National Practice Guideline

Page 14: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

Scope of the Problem

From 1999 to 2008, overdose death rates, sales and substance use disorder treatment admissions related to prescription pain relievers increased in parallel. The overdose death rate in 2008 was nearly four times the 1999 rate; sales of prescription pain relievers in 2010 were four times those in 1999, and the SUD admission rate was 6 times higher

Drug overdose is the leading cause of accidental death in the US, with 47,055 lethal drug overdoses in 2014. Opioid addiction is driving this epidemic, with 18,893 overdose deaths related to prescription pain relievers, and 10,574 overdose deaths related to heroin in 2014

Fastest-growing demographic: 12 – 24 year olds!

Page 15: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

The Scope of the Problem

Rx Opioid Trends: 1999-2010

SAMHSA - NSDUH 2014.

National Vital Statistics System, 1999-2010; Automation of Reports and Consolidated Orders System of the DEA; Treatment Episode Data Set

Page 16: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

ASAM National Practice Guideline

Page 17: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

The Scope of the Problem

Opioid Overdose Trends: 2000-2013

CDC/NCHS National Vital Statistics System NCHS Data Brief No. 190 March 2015 Dart RC et al. N Engl J Med. 2015;372:241-8

Page 18: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

ASAM National Practice Guideline

Page 19: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

Why the need for

Medication-Assisted

Treatment?

NIH Effective Treatments for Opioid Addiction

Page 20: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

Opiates and Opioids Opiates are present in opium e.g. morphine,

codeine, thebaine (codeine methylenol ether)

Opioids are manufactured as

Semi-synthetic opioids derived from an opiate (e.g. heroin from morphine)

Synthetics opioids completely synthesized to have function similar to natural

opiates (e.g. methadone)

Page 21: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment
Page 22: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

A Brief History of Opioid Treatment

• 1964: Methadone is approved.

• 1974: Narcotic Treatment Act limits methadone treatment to specifically licensed Opioid Treatment Programs (OTPs).

• 1984: Naltrexone is approved, but has continued to be rarely used (approved in 1994 for alcohol addiction).

• 1993: LAAM (long-acting methadone) is approved for non-pregnant patients only, but underutilized.

Page 23: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

A Brief History of Opioid Treatment

• 2000: Drug Addiction Treatment Act of 2000 (DATA 2000) expands the clinical context of medication-assisted opioid treatment.

• 2002: Tablet formulations of buprenorphine (Subutex®) and buprenorphine/naloxone (Suboxone®) were approved by the Food and Drug Administration (FDA).

• 2004: Sale and distribution of ORLAAM® is discontinued.

Page 24: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

Jul 13, 2016 - Expansion of office-based treatment by allowing nurse practitioners and physician assistants to prescribe buprenorphine for opioid addiction. Authorization of grants to opioid treatment programs and practitionerswho offer office-based medication-assisted treatment to expand access to naloxone through co-prescribing.

Feb 28, 2017 - Qualify for Nurse Practitioners (NPs) and Physician Assistants (PAs) Waiver. (PAs) can train and apply to become DATA-waiver practitioners. Nurse Practitioners and PAs need to complete 24 hours of training to be eligible for a prescribing waiver.

https://www.samhsa.gov/medication-assisted-treatment/qualify-nps-pas-waivers

NOTE: Please ensure that your state regulations allow you to prescribe buprenorphine and other medications to treat OUD before you apply for the waiver. Some states may have overriding state legislation that will prevent NPs from prescribing these medications even if Federal law allows it. PA’s can only prescribe under a supervising waivered physician.

A Brief History of Opioid Treatment (con’t)

Page 25: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

Medically Supervised Withdrawal“Opioid Acute Detoxification”

Low rates of retention in treatment

High rates of relapse post-treatment< 50% abstinent at 6 months< 15% abstinent at 12 months

“Detox” is not treatment, it is just the start of abstinence

Increased rates of overdose due to decreasedtolerance

O’Connor PG. JAMA. 2005.Mattick RP, Hall WD. Lancet. 1996.Stimmel B et al. JAMA. 1977.

Page 26: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

Reasons for Relapse

Protracted abstinence syndrome (chronic withdrawal)

Generalized malaise, fatigue, insomnia Poor tolerance to stress and pain

(artificially lowered threshold) Opioid craving

Conditioned cues (triggers) Priming with small dose of drug

Kleber H et al. Dialogues Clin Neurosci. 2007.

Page 27: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

Opiate RewardReinforcement

Reward/Reinforcement is in part controlled by mu receptors in the Reward Pathway:

Ventral Tegmental Area (VTA) Nucleus Accumbenswith projections to Prefrontal CortexDopaminergic system

Page 28: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

DSM 5 Opioid Use Disorders1

1. Tolerance2

2. Withdrawal2

Loss of Control3. Larger amounts and/or

longer periods4. Inability to cut down on

or control use5. Increased time spent

obtaining, using or recovering

6. Craving/Compulsion

Use Despite Negative Consequences

7. Role failure, work, home, school8. Social, interpersonal problems9. Reducing social, work,

recreational activity10. Physical hazards11. Physical or psychological harm

1 Mild (2-3), F11.10moderate (4-5), severe (≥6) F11.202 Not valid if opioid taken as prescribed ICD-10 F11.929 (eg. Chronic pain)APA (2013) Diagnostic and statistical manual of mental disorders (5th ed.)

Page 29: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

Wit

hdra

wal

Euph

oria

Chronic useTolerance & Physical Dependence

Natural History of Opioid Use Disorder

Nor

mal

Acute use

Episodic use

Page 30: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

Opioid Tolerance & Physical DependenceBoth tolerance and physical dependence are

physiological adaptations to chronic opioid exposure

Tolerance:Increased dosage needed to produce specific effect

Develops rapidly for CNS and respiratory depression

Physical Dependence:Signs and symptoms of withdrawal by

abrupt opioid cessation, rapid dosereduction

Page 31: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

Wit

hdra

wal

Euph

oria

Chronic useTolerance & Physical

Dependence

Treatment of Opioid Use Disorder w Medication

Nor

mal Acute use

Episodic use

Opioid Agonist Therapy

methadone buprenorphine

Page 32: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

Anxiety, Drug Craving0

Vomiting / dehydration, Diarrhea, Abdominal cramps, Curled-up body position4

Nausea, extreme restlessness, elevated blood pressure, Heart rate > 100, Fever 3

Dilated pupils, Gooseflesh, Muscle twitching & shaking, Muscle & Joint aches, Loss of appetite2

Yawning, Sweating, Runny nose, Tearing eyes, Restlessness Insomnia1

Symptoms / SignsGrade Acute Opioid Withdrawal

pulse, sweating, restlessness & anxiety, pupil size, aches, runny nose & tearing, GI sx, tremor, yawning, gooseflesh

5-12 mild, 13-24 moderate 25-36 moderately severe >36 severe

Clinical Opiate Withdrawal Scale (COWS):

Page 33: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

COWS: Clinical Opioid

Withdrawal Scale

Page 34: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

*Protocol Developed by NIDA Clinical Trials Network

Study Day Buprenorphine-Naloxone Dose mg

1 4 + additional 4 as needed

2 8

3 16

4 14

5 12

6 10

7 8

8 6

9 4

10 2

11 2

Withdrawal over 4-30 days is common in clinical practice. Buprenorphine is very flexible and withdrawal can be achieved rapidly or slowly, depending on treatment issues.

Medically Supervised Withdrawal “Detox” using Buprenorphine 30 days*

Page 35: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

Injectable Naltrexone - Vivitrol® Multicenter (13 sites in Russia) Funded by Alkermes DB RPCT, 24 wks, n=250 w/ opioid dependence

XR-NTX vs placebo, all offered biweekly individual drugcounseling

Increased weeks of confirmed abstinence (90% vs 35%)

Increased patients with confirmed abstinence (36% vs 23%)

Decreased craving (-10 vs +0.7)

Krupitsky E et al. Lancet. 2011.

(No Black Box LFTs Warning Label for IM formulation)

Page 36: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

Medications to Treat Opioid Use Disorder Goals

Alleviate signs/symptoms of physical withdrawalOpioid receptor blockadeDiminish and alleviate drug cravingNormalize and stabilize perturbed brain neurochemistry

OptionsOpioid Antagonist

Naltrexone (full opioid antagonist)

Opioid AgonistMethadone (full opioid agonist)

Buprenorphine (partial opioid agonist)

Page 37: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

Polling Question # 1:Do you believe that a person being treated with methadone, buprenorphine or suboxonecan be considered “in recovery”?(a) no, they are still taking an addictive

substance(b) yes, as long as they’re taking it only as

prescribed(c) only if they no don’t have other

symptoms of SUDs

Page 38: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

Buprenorphine Treatment: The Myths and The Facts

Page 39: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

MYTH #1: Patients are still addicted

FACT: Addiction is pathologic use of a substance and may or may not include physical dependence.

Physical dependence on a medication for treatment of a medical problem does notmean the person is engaging in pathologic use and other behaviors.

Page 40: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

MYTH #2: Buprenorphine is simply a substitute for heroin or other opioidsFACT: Buprenorphine is a replacement medication;

it is not simply a substitute Buprenorphine is a legally prescribed

medication, not illegally obtained. Buprenorphine is a medication taken

sublingually, a very safe route of administration. Buprenorphine allows the person to function

normally.

Page 41: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

MYTH #3: Providing medication alone is sufficient treatment for opioid addiction

FACT: Buprenorphine is an important treatment option. However, the complete treatment package must include other elements, as well.

Combining pharmacotherapy with counseling and other ancillary services increases the likelihood of success.

Page 42: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

MYTH #4: Patients are still getting high

FACT: When taken sublingually, buprenorphine is slower acting, and does not provide the same “rush” as heroin.

Buprenorphine has a ceiling effect resulting in lowered experience of the euphoria felt at higher doses.

Page 43: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

Studies (RCT) show buprenorphine moreeffective than placebo and equally effectiveto moderate doses (80 mg) of methadone onprimary outcomes of: Abstinence from illicit opioid use Retention in treatment Decreased opioid craving

Johnson et al. NEJM. 2000. Fudala PJ et al. NEJM. 2003. Kakko J et al. Lancet. 2003.

Page 44: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

Oral Naltrexone Efficacy (opioid MAT)Oral naltrexone

Duration of action 24-48 hours FDA approved 1984

10 RCTs ~700 participants to naltrexone alone or with psychosocialtherapy compared with psychosocial therapy alone or placebo

No clear benefit in treatment retention or relapse at follow up

Benefit in highly motivated patients Impaired physicians > 80% abstinence at 18 months Close monitoring and frequent Urine drug screens MUCH better research outcomes for alcohol

Cochrane Database of Systematic Reviews 2006

Page 45: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

Buprenorphine Formulations Sublingual forms (tablets and films)

“Combo” (buprenorphine/naloxone)

“Mono” (buprenorphine only) Approved for moderate to severe Opioid Use Disorders

Can be used OFF LABEL for pain

Parenteral and transdermal patch forms Approved for pain but NOT OUDs

Can not be used OFF LABEL for OUDs

Page 46: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

Purpose of Naloxone in “combo” Naloxone has limited bio-availability by mouth or

sublingual, but is active parenterally (e.g. injectedsubcutaneous, IM or IV)

The combo product, if crushed, dissolved and injected the: naloxone may cause initial withdrawal if the person is

physically opioid - dependent. decreasing diversion and misuse naloxone will block, or attenuate, the opioid agonist

effect of the buprenorphine therefore safer if diverted

Comer S. Addiction. 2010.

Page 47: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

Buprenorphine/Naloxone Bioavailability If dissolved sublingually

Buprenorphine is active Naloxone is not active

If swallowed Buprenorphine not active (minimal oral bioavailability) Naloxone not active

If injected Buprenorphine active, but Naloxone active x 20 minutes so attenuates the

parenteral “rush”

Not time-released so tablets/film strip can be split

Page 48: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

Buprenorphine Safety Highly safe medication

for both acute and chronic dosing

Primary side effects:

nausea and constipation (like other mu agonist opioids, but may be less severe and more self-limiting)

No evidence of significant disruption in cognitive or psycho-motor performance with buprenorphine maintenance

No evidence of organ damage with chronic dosing of Buprenorphine “mono” or “combo”

Page 49: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

Abuse Potential of Buprenorphine Euphoria in non-opioid dependent individuals Abuse potential less than full opioid agonists Abuse among opioid-dependent individuals is

relatively low Combination product theoretically less likely to be

abused by IV route Most illicit use is to prevent or treat withdrawal

and cravings

Yokel MA et al. Curr Drug Abuse Rev. 2011. Lofwall MR, Walsh SL. J Addic Med. 2014.

Page 50: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

Concurrent sedative-hypnotics?Use or abuse of alcohol and other sedative-hypnotics are relative contraindications to buprenorphine Deaths have resulted from injecting buprenorphine

and benzodiazepines Avoid alcohol while taking buprenorphine to avoid

overdose

Identify and refer patients who are willing and able to undergo medically supervised withdrawal management from alcohol, benzodiazepines, or other sedatives

Fishman et al. 2005; McNicholas, 2008; Lavie et al. 2005.

Page 51: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

All best practices require frequent Urine Drug Screening for compliance

Drug/Medication Primary Metabolite Ave. Detection Time (days)

Opiates (heroin, morphine) Morphine 2-3

Semisynthetic Opioids(oxycodone, hydrocodone)

VariableMust be tested specifically

2-3

Methadone EDDP 2-3

Buprenorphine Nor-buprenorphine 2-3

Cocaine benzoylecgonine 2-3

Amphetamines 2-3

Benzodiazepine Varies by medication type Variable with half lifeUnreliable immunoassays

Marijuana OccasionalMarijuana Chronic

THC 1-3 Up to 30

Page 52: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

Polling Question #2

As a Counselor, how comfortable would you be in treating patients on MAT?(a) I am pretty confident (b) I’m willing, but I need more training (c) I don’t feel comfortable myself, but I’m notopposed to MAT(d) I’m opposed to MAT for most clients

Page 53: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

The “Bible”

Page 54: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

ASAM National Practice Guideline

Page 55: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

Before you

begin… what

are your biases?

Page 56: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

• Identify and refer any acute medical or psychiatric needs

• Physical exam & labs – LFTs, Hepatitis, HI V etc.• Pregnancy test & contraception queries

• Full Mental Health assessment• Evaluation of past & present Substance Use

• Poor prognosis with other SUDs• Tobacco use & cessation counseling

• Social & environmental factors

BIOPSYCHOSOCIAL ASSESSMENT

Page 57: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

ASAM National Practice Guideline

Page 58: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

ASAM National Practice Guideline

Page 59: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

ASAM National Practice Guideline

Page 60: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

ASAM National Practice Guideline

Page 61: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

ASAM National Practice Guideline

Page 62: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

ASAM National Practice Guideline

Page 63: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

ASAM National Practice Guideline

Page 64: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

ASAM National Practice Guideline

Page 65: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

ASAM National Practice Guideline

Page 66: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

ASAM National Practice Guideline

Page 67: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

ASAM National Practice Guideline

Page 68: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

ASAM National Practice Guideline

Page 69: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

ASAM National Practice Guideline

Pregnancy

Chronic pain

Adolescents

PsychiatricDisorders

Criminal Justice

Page 70: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

Pregnancy: Benefits of Opioid Agonist Therapy

Maternal Benefits Fetal Benefits 70% reduction in

overdose related deaths Decrease in risk of HIV,

HBV, HCV Increased engagement in

prenatal care and recovery treatment

Reduces fluctuations in maternal opioid levels; reducing fetal stress

Decrease in intrauterine fetal demise

Decrease in intrauterine growth restriction

Decrease in preterm delivery

Page 71: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

ASAM National Practice Guideline

Page 72: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

Opioid Use Disorder and Breastfeeding The transfer of methadone and into human milk is

minimal and unrelated to maternal doses Buprenorphine has poor oral bioavailability and is

also compatible with breastfeedingThe amount of buprenorphine in human milk is small

and unlikely to have negative effects on the infant

Both are considered Category L3 (probably compatible)

McCarthy JJ 2000; Begg EJ 2001; Jansson LM 2007 & 2008; Hale 2008; Grimm 2005; Lindemalm 2008; Ilett 2012.

Page 73: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

ASAM National Practice Guideline

Page 74: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

Detoxification in pregnancy? Initial studies from 1970s demonstrated fetal distress

and 5 fold increase in still birth rates withantepartum detoxification (Zuspan et al. 1975; Rementeria et al. 1973.)

More recent data shows 2nd trimester detoxificationcanbe safe for the fetus however maternal relapserates prior to delivery range from 70-98%

(Luty et al. 2003; Maas et al. 1990; Dashe et al. 1998.)

Maintenance therapy in pregnancy has been shown to increase retention in prenatal care,addiction recovery and in-hospital deliveries (Jones et al. 2008.)

Page 75: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

ASAM National Practice Guideline

Important to differentiate

between physiological dependence

withoutdysfunction

or active SUD – may

suggest different

EBP’s

Page 76: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

ASAM National Practice Guideline

Physiological dependence

withoutdysfunction: concentrate

on pain management

Active SUD requires

treatment emphasis

Page 77: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

ASAM National Practice Guideline

Page 78: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

Current treatment options for opioid-addicted adolescents and young adults are often unavailable and when found, clinicians report that the outcome leaves much to be desired.

States have different requirement for admitting clients under age 18 to addictions treatment. It is important to know the local requirements.

Opioid-Addicted Adolescents and Young Adults

Page 79: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

Buprenorphine is approved for use with opioid dependent persons age 16 and older

Research conducted through the NIDA Clinical Trials Network (CTN 010) demonstrated that it can be safely and effectively used with young adults.

This research also indicated that medical treatment likely needs to be longer than current standard treatment indicates.

Opioid-Addicted Adolescents and Young Adults

Page 80: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

Use of Pharmacologic Treatment with Adolescents

Pharmacologic therapy is recommended for alladolescents with severe opioid use disorder

Buprenorphine is considered first line treatment Most methadone clinics cannot admit patients under 18 years

old, though methadone may be a good option for young adultswith unstable living arrangements as daily visits providestructure and eliminate the need to manage medications athome

Naltrexone is also an option for adolescents and also may beclinically useful for adolescents/young adults living away fromhome, or patients with co-occurring alcohol use disorders

Page 81: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

ASAM National Practice Guideline

Co-OccurringMental Disorders

Page 82: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

ASAM National Practice Guideline

Co-OccurringMental Disorders

Page 83: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

ASAM National Practice Guideline

Page 84: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

ASAM National Practice Guideline

Page 85: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

NOTE: these are considered “off-label” uses

The National Institute of Drug Abuse (NIDA) established the Methamphetamine Clinical Trials Group (MCTG) to conduct studies of medications for methamphetamine.

Paxil (Paroxetine or Pexeva)Modafinil (Provigil®)Mirtazapine (Remeron)Naltrexone (ReVia® Vivitrol ® )

www.addictionrecoveryguide.org/medication/methamphetamine

Source: University of California - Los Angeles May 19, 2015 Summary: The first study in the United States of Naltrexone's effect on methamphetamine users has found that this medication, approved by the US Food and Drug Administration for the treatment of alcoholism, is potentially a very promising treatment for methamphetamine addiction, researchers report.

Page 86: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

MAT and Pain Management

• Maintenance opioid agonists provide pain relief.

• Use of opioids for pain relief may result in addiction or relapse

• Combining opioid analgesics and opioid agonist therapy may cause respiratory and central nervous system depression.

• The pain complaint may be a manipulation to obtain medications to feel “high.”

Common Misconceptions

Page 87: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

Buprenorphine and Pain Management• Little clinical experience documented

• Acute Pain– Initially treat with non-opioid analgesics– Pain not relieved by non-opioid medications, follow

usual pain management protocol

• Chronic Pain– May not be good candidate for buprenorphine

treatment because of the ceiling effect

Page 88: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

MAT for Alcohol

Medications approved to support abstinence

from alcohol

Page 89: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

Transtheoretical Model and MAT

There are motivational strategies which are

appropriate for each stage of

change…

Page 90: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

Transtheoretical Model and MAT (con’t)

There are motivational strategies which are

appropriate for each stage of

change…

Page 91: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment
Page 92: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment
Page 93: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment
Page 94: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment
Page 95: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

Disulfiram or Antabuse

Page 96: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment
Page 97: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment
Page 98: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment
Page 99: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment
Page 100: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment
Page 101: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment
Page 102: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

Polling Question #3

If I were to do MAT for alcohol patients, I would most likely recommend(a) Disulferam (antabuse)(b) Acamprosate(c) oral Naltrexone (ReVia®)(d) Naltrexone injection (Vivitrol®)

Page 103: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

Module VI: Counseling Buprenorphine Patients

BUPRENORPHINE TREATMENT: A Training For Multidisciplinary Addiction Professionals

Page 104: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

Opioid Drug use historyAlcohol & other drug useSocial Issues – strengthsSocial Services – barriers? Psychological history and statusEducation – attainments & needsVocational – history & future goals

Areas of Needs Assessment

Page 105: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

Counselor Responses:Be flexibleDon’t impose high expectationsDon’t confrontBe non-judgmental Use a motivational interviewing approachProvide support & reinforcement

Counseling Buprenorphine Patients

Page 106: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

Address issues of the necessity of counseling with medication for recovery.

Recovery and Pharmacotherapy:Patients may have ambivalence regarding

medication.The recovery community may ostracize patients

taking medication.Counselors need to be aware fo their biases, have

accurate information and appropriate training

Counseling Buprenorphine Patients

Page 107: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

Issues in 12-Step Meetings:Medication and the 12-Step programs

Program policy “The AA Member: Medications and Other Drugs”

“We are not Doctors”NA: “The ultimate responsibility for making

medical decisions rests with each individual”Some meetings are more accepting of medications

than others

Counseling Buprenorphine Patients

Page 108: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

A Motivational Interviewing Approach:Dealing with other drugs and alcoholDoing more than not-using

MIA-STEPDeveloped through the Blending InitiativeEmpirically supported mentoring products to enhance the MI skills of treatment providersProvides tools to help supervisors offer structured, focused, and effective supervision. The blending products are available at www.drugabuse.gov/Blending www.attcnetwork.org

Counseling Buprenorphine Patients

Page 109: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

NIDA CTN research shows that treatment retention and drug abstinence are improved by providing low-cost reinforcement (prizes, vouchers, clinic privileges, etc.), for drug negative urine tests.The Blending Product Promoting Awareness of Motivational Incentives (PAMI) provides information on this effective technique. The blending products are available at: www.drugabuse.gov/Blending www.attcnetwork.org

Using Motivational Incentives

Page 110: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

Relapse Prevention: Sample TopicsDangerous Emotions

Loneliness, anger, deprivationBe Smart, not Strong

Avoid the dangerous people and placesDon’t rely on will power

Avoiding Relapse DriftIdentify “mooring lines”Monitor drift

Counseling Buprenorphine Patients

Page 111: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

Pharmacotherapy alone is insufficient to treat drug addiction.

Prescribing Providers are responsible for providing or referring patients to counseling.

Contingencies should be established & agreed for patients who fail to follow through on referrals.

Patient Management Issues

Page 112: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

Goals for treatment should include:No illicit opioid drug use No other drug use or diversionAbsence of adverse medical effectsAbsence of adverse behavioral effectsResponsible handling of medicationAdherence to treatment plan

Patient Management: Treatment Monitoring

Page 113: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

Trigger

A trigger is a stimulus which has been repeatedly associated with the preparation for, anticipation of, or use of drugs and/or alcohol. These stimuli include people, things, places, times of day, and emotional states.

(Center for Substance Abuse Treatment, 2006)

Page 114: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

A strong desire for something – limbic activation of “acquired drive state”

Does not always occur in a straightforward way

It takes effort to identify and stop a drug-use related thought.

The further the thoughts are allowed to go, the more likely the individual is to use drugs.

Issues in Recovery: Craving

(Center for Substance Abuse Treatment, 2006)

Page 115: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

Triggers & Cravings

Trigger Thought Craving Use

During addiction, triggers, thoughts, and craving can run together. The usual sequence, however, is as follows:

The key to dealing with this process is to not allow for it to start. Stopping the thought when it first begins helps prevent it from building into a craving.

(Center for Substance Abuse Treatment, 2006)

Page 116: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

However, the

relapse process

isn’t always linear

In your handouts – permission to reproduce

Page 117: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

Often, relapse can start innocently enough…

In your handouts – permission to reproduce

Page 118: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

VisualizationSnappingRelaxationCalling someone

Thought-Stopping Techniques

(Center for Substance Abuse Treatment, 2006)

Page 119: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

New Evidence-Based Practices for MAT

Opioids: COR-12 (Comprehensive Opioid Response with the 12 Steps - Hazelden)

Methamphetamine: STAGE - 12 (NIDA ClinicalTrials Network)

Chronic Pain (opioid dependence w/o evidence ofuse disorder): Illness Management and Recovery and Acceptance & Commitment Therapy (ACT)

Page 120: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

May be more appropriate for chronic

pain patients w/o evidence of “addiction” – there is no “expectation

of abstinence”

Page 121: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

The Model addresses

chronicstressors,

mental health and symptom

mgmt. skills

Page 122: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment
Page 123: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment
Page 124: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

Acceptance & Commitment Therapy for Chronic Pain

ACT helps patients to

change their “relationship” with their pain using “radical acceptance” –

completely compatible with MAT

Page 125: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment
Page 126: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

46 opioid overdose deaths every day

Page 127: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment
Page 128: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

COR-12 Medication Pathways

Options increase patientchoice

and buy-in

Page 129: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment
Page 130: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

DuPont, RL & Gold, MS: Journal of Addictive Diseases vol 26 no 1

“Isn’t this just anotherdrug?”

Page 131: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

How Long Should Buprenorphine Maintenance Continue?

No data to provide guidance on how long to treat a patient with buprenorphine/naloxone maintenance

Studies as long as 16 weeks show high relapse rates with medical withdrawal (Weiss et al., 2011)

Patients can be retained long term; showed approximately 75% retention at one year with maintenance (Kakko et al., 2003)

Continue maintenance as long as patient is benefitting from treatment (opioid/other drug use, employment, educational goals pursued, improvement in relationships, improvement in medical/mental illnesses, engaged in psychosocial treatment)

Page 132: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

“How do I know that I’m ready to stop treatment?”

Page 133: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

Needs work Progress Complete

Page 134: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

Needs work Progress Complete

Page 135: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

Polling Question #4

Of the EBPs for Medication-Assisted Treatment, the one I want to know more about is(a) the general buprenorphine counseling(b) COR – 12 for opioids(c) Illness Management & Recovery(d) ACT for chronic pain(e) STEP – 12 for methamphetamine

Page 136: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

Thank You!

Page 137: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

Thank You for your interest and attention!

Your

Michael G Bricker MS, CADC-II, LPC

Behavioral Health ClinicianAdult SUD Treatment Mgr.

Klamath Falls, [email protected]

Page 138: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

Michael G. Bricker MS, CADC-II, LPC

Consultation in recovery from

substance use and mental disorders

The STEMSS ® InstituteSupport Together for Emotional & Mental Serenity and Sobriety

PO Box 10285341 Bryant AvenueKlamath Falls OR 97601

Phone: (541) 880 - 8886Email: [email protected]

Promoting dual recovery since 1984

Page 139: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

www.naadac.org/evidence-based-MAT-practices-webinar

Page 140: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

Cost to Watch:Free

CE Hours Available:2 CEs

CE Certificate for NAADAC Members:Free

CE Certificate for Non-members:$25

To obtain a CE Certificate for the time you spent watching this webinar:

1. Watch and listen to this entire webinar.

2. Pass the online CE quiz, which is posted at

www.naadac.org/evidence-based-MAT-practices-webinar

3. If applicable, submit payment for CE certificate or join NAADAC.

4. A CE certificate will be emailed to you within 21 days of submitting the quiz.

CE Certificate

Page 141: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

August 9, 2017 September 13, 2017

August 23 2017 September 27, 2017

Upcoming Webinars

www.naadac.org/webinars

Value-Based Reimbursement: Huge Opportunities for Treatment Programsby Richard Brown, MD, MPH

Co-Occurring/Interrelated Domestic Violenceand Substance Use Disorders

By Terry Gray, MS

Electronic Screen Addiction: Don’t Take My Ice Creamby Christina Migliara, LMFT, MAC, CAP, CASAC and Beth Donnellan, MEd, ABD, FT

Addiction as a Relational Disorder: A Neuro-Informed Treatment Perspective by Chad Luke, PhD, LPC/MHSP, NCC, ACS, MAC

Page 142: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

www.naadac.org/webinars

Free CEs for Members

Levels:Professional AssociateStudent

www.naadac.org/join

Page 143: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

Over 75 CEs of free educational webinars are available. Education

credits are FREE for NAADAC members.

WEBINAR SERIES

In each issue of Advances in Addiction & Recovery, NAADAC's

magazine, one article is eligible for CEs.

MAGAZINE ARTICLES

NAADAC offers face-to-face seminars of varying lengths in the

U.S. and abroad.

FACE-TO-FACE SEMINARS

Earn CEs at home and at your own pace (includes study guide and online examination).

INDEPENDENT STUDY COURSES

NAADAC Annual Conference, September 22-26, 2017, Denver, CO

CONFERENCES

Demonstrate advanced education in diverse topics with the NAADAC Certificate Programs.

CERTIFICATE PROGRAMS

Page 144: “NOW What’re We Supposed to Do?” · 7/26/2017  · MYTH #3: Providing medication alone is sufficient treatment for opioid addiction FACT:Buprenorphine is an important treatment

Contact Us!NAADAC44 Canal Center Plaza, Suite 301Alexandria, VA 22314phone: 703.741.7686 / 800.548.0497 fax: 703.741.7698 / [email protected]

NAADACorg

Naadac

NAADAC