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Are hospital readmissions in the elderly preventable? Antonio Sarría-Santamera MD PhD Institute of Health Carlos III University of Alcalá DUKE-NUS HSSR SEMINAR May 29 th , 2015

Are hospital readmissions in the elderly preventable? Antonio Sarría-Santamera MD PhD Institute of Health Carlos III University of Alcalá DUKE-NUS HSSR

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Page 1: Are hospital readmissions in the elderly preventable? Antonio Sarría-Santamera MD PhD Institute of Health Carlos III University of Alcalá DUKE-NUS HSSR

Are hospital readmissions in the elderly preventable?

Antonio Sarría-Santamera MD PhDInstitute of Health Carlos III

University of Alcalá

DUKE-NUS HSSR SEMINARMay 29th, 2015

Page 2: Are hospital readmissions in the elderly preventable? Antonio Sarría-Santamera MD PhD Institute of Health Carlos III University of Alcalá DUKE-NUS HSSR

• The Spanish health care system• Should we care about this problem?• What we did• Some reflections

Page 3: Are hospital readmissions in the elderly preventable? Antonio Sarría-Santamera MD PhD Institute of Health Carlos III University of Alcalá DUKE-NUS HSSR

Spanish Health Care System

• National Health Care System• Network of hospitals-specialists/GPs-PC centers• Population based budget• Doctors are salaried• GPS: Gate-keeping for specialists• Free at the point of service (no copayments for

medical services)• Copayment for medicines prescribed for

ambulatory patients

Page 4: Are hospital readmissions in the elderly preventable? Antonio Sarría-Santamera MD PhD Institute of Health Carlos III University of Alcalá DUKE-NUS HSSR

Prevention is worth• The condition sought should be an important health problem• There should be an accepted treatment.• Facilities for diagnosis and treatment should be available.• There should be a recognizable latent or early symptomatic stage.• There should be a suitable test or examination.• The test should be acceptable to the population.• The natural history of the condition, including development from latent to

declared disease, should be adequately understood.• There should be an agreed policy on whom to treat as patients.• The cost of case-finding (including diagnosis and treatment of patients

diagnosed) should be economically balanced in relation to possible expenditure on medical care as a whole.

• Case-finding should be a continuing process and not a “once and for all” project.

Wilson . JMG, Jungner G. Principles and practice of screening for disease. Geneva: WHO; 1968

Page 5: Are hospital readmissions in the elderly preventable? Antonio Sarría-Santamera MD PhD Institute of Health Carlos III University of Alcalá DUKE-NUS HSSR

ARE READMISSIONS IN THE ELDERLY A PUBLIC HEALTH PROBLEM?

Page 6: Are hospital readmissions in the elderly preventable? Antonio Sarría-Santamera MD PhD Institute of Health Carlos III University of Alcalá DUKE-NUS HSSR

Evolution hospital readmissions

Page 7: Are hospital readmissions in the elderly preventable? Antonio Sarría-Santamera MD PhD Institute of Health Carlos III University of Alcalá DUKE-NUS HSSR

Hospital readmissions for specific conditions

COPD HEART FAILURE

Page 8: Are hospital readmissions in the elderly preventable? Antonio Sarría-Santamera MD PhD Institute of Health Carlos III University of Alcalá DUKE-NUS HSSR

Hospital readmissions by age groups

2007 2008 2009 2010 2011 20124.00

5.00

6.00

7.00

8.00

9.00

10.00

11.00

12.00

15-4445-6465-74>74 años

Page 9: Are hospital readmissions in the elderly preventable? Antonio Sarría-Santamera MD PhD Institute of Health Carlos III University of Alcalá DUKE-NUS HSSR

Readmissions >74 year old

_x0004_2

001

_x0004_2

002

_x0004_2

003

_x0004_2

004

_x0004_2

005

_x0004_2

006

_x0004_2

007

_x0004_2

008

_x0004_2

009

_x0004_2

010

_x0004_2

011

_x0004_2

01210

12

14

16

18

20

22

Heart failure COPD

Page 10: Are hospital readmissions in the elderly preventable? Antonio Sarría-Santamera MD PhD Institute of Health Carlos III University of Alcalá DUKE-NUS HSSR
Page 11: Are hospital readmissions in the elderly preventable? Antonio Sarría-Santamera MD PhD Institute of Health Carlos III University of Alcalá DUKE-NUS HSSR

Complexity

• Aging, clinical conditions and functional status• Social conditions• Utilization of services• Relationships across professionals and levels

of care• Methodological approaches

Page 12: Are hospital readmissions in the elderly preventable? Antonio Sarría-Santamera MD PhD Institute of Health Carlos III University of Alcalá DUKE-NUS HSSR

• Observational study

• Systematic review of evidence

• Qualitative study

Page 13: Are hospital readmissions in the elderly preventable? Antonio Sarría-Santamera MD PhD Institute of Health Carlos III University of Alcalá DUKE-NUS HSSR

COHORT STUDY

Page 14: Are hospital readmissions in the elderly preventable? Antonio Sarría-Santamera MD PhD Institute of Health Carlos III University of Alcalá DUKE-NUS HSSR

METHODS

• Patients >74 year old discharged from HUPA• Index admission: no admission in the previous 6

months• All patients were followed for 6 months.

• Source of information:– EMR PC + hospital

Page 15: Are hospital readmissions in the elderly preventable? Antonio Sarría-Santamera MD PhD Institute of Health Carlos III University of Alcalá DUKE-NUS HSSR

RESULTS

• 1.051 included• 22,6% readmission in 6 months after the index admission

• Variables associated with an increased risk:– LOS– Number of prescriptions– Hypertension– Heart failure– Ischemic heart disease

• Variables associated with a protective effect:– Visits at nurses at PC

Page 16: Are hospital readmissions in the elderly preventable? Antonio Sarría-Santamera MD PhD Institute of Health Carlos III University of Alcalá DUKE-NUS HSSR

SYSTEMATIC REVIEWFACTORS ASSOCIATED WITH READMISSIONS

Page 17: Are hospital readmissions in the elderly preventable? Antonio Sarría-Santamera MD PhD Institute of Health Carlos III University of Alcalá DUKE-NUS HSSR

Inclusion criteria

• Prospective studies with appropriate statistical analysis, that explored the relationship between risk of readmission with clinical, socio-demographic or other factors in elderly patients (aged at least 75 years) admitted to hospital.

Page 18: Are hospital readmissions in the elderly preventable? Antonio Sarría-Santamera MD PhD Institute of Health Carlos III University of Alcalá DUKE-NUS HSSR

Exclusion criteria

• Studies that focused on patients with specific diseases or conditions (terminal patients, psychiatric patients, heart failure, chronic obstructive pulmonary disease, etc.)

• Studies where >50% of the patients or the average age was <75 years.

Page 19: Are hospital readmissions in the elderly preventable? Antonio Sarría-Santamera MD PhD Institute of Health Carlos III University of Alcalá DUKE-NUS HSSR
Page 20: Are hospital readmissions in the elderly preventable? Antonio Sarría-Santamera MD PhD Institute of Health Carlos III University of Alcalá DUKE-NUS HSSR
Page 21: Are hospital readmissions in the elderly preventable? Antonio Sarría-Santamera MD PhD Institute of Health Carlos III University of Alcalá DUKE-NUS HSSR

LIMITATIONS

• Methodological aspects• Different periods of time:– Short (2 weeks-30 days)– Long (2-3 months)

Page 22: Are hospital readmissions in the elderly preventable? Antonio Sarría-Santamera MD PhD Institute of Health Carlos III University of Alcalá DUKE-NUS HSSR

FACTORS ASSOCIATED WITH READMISSION

1. An admission before the index admission2. Length of stay3. Multi-morbidity poly-pharmacy4. Functional capacity5. Social factors

Page 23: Are hospital readmissions in the elderly preventable? Antonio Sarría-Santamera MD PhD Institute of Health Carlos III University of Alcalá DUKE-NUS HSSR

Systematic review

• Functional status score, illness severity, co-morbidity, polypharmacy, and age.

• Campbell. Age and Ageing 2004; 33: 110–115

Page 24: Are hospital readmissions in the elderly preventable? Antonio Sarría-Santamera MD PhD Institute of Health Carlos III University of Alcalá DUKE-NUS HSSR

SYSTEMATIC REVIEW EFFECTIVE INTERVENTIONS TO PREVENT READMISSION

Page 25: Are hospital readmissions in the elderly preventable? Antonio Sarría-Santamera MD PhD Institute of Health Carlos III University of Alcalá DUKE-NUS HSSR

Inclusion criteria

• Controlled trials, both randomized as well as nonrandomized, which assessed an intervention carried out during admission and/or the follow-up in order to reduce readmissions of elderly patients admitted to hospital for any medical problem (studies focusing on a specific disease were excluded).

• One of the outcome measures (not necessarily the primary one) had to be unplanned hospital readmission (absolute differences, risk ratio, odds ratio).

• Studies were excluded if more than half of participants were younger than 75 years or if the average age of all participants was less than 75 years.

Page 26: Are hospital readmissions in the elderly preventable? Antonio Sarría-Santamera MD PhD Institute of Health Carlos III University of Alcalá DUKE-NUS HSSR
Page 27: Are hospital readmissions in the elderly preventable? Antonio Sarría-Santamera MD PhD Institute of Health Carlos III University of Alcalá DUKE-NUS HSSR

LIMITATIONS• Complexity and variability of the interventions reviewed in this work, and

of their methodologies: it was not possible to make direct comparisons between studies.

• Strong variability in the indicators used to measure readmissions, which can be expressed in terms of the number (or percentage) of events or the number of patients readmitted during a given period.

• Some studies measured the number of days from the admission to the first readmission, others counted patients according to their number of readmissions.

• Distinct lengths of the follow-up period and of the measurement times, which ranged from 15 days to 1 year post discharge.

• Differences in the treatment provided to the control groups, although the majority of the studies compared the intervention with ‘usual care’ (almost never described in detail).

• Hence, this care may vary according to the health care system of each country and it may include some components of geriatric management.

Page 28: Are hospital readmissions in the elderly preventable? Antonio Sarría-Santamera MD PhD Institute of Health Carlos III University of Alcalá DUKE-NUS HSSR

EFFECTIVE INTERVENTIONS

1. Coordination hospital-PC2. Home care component

Page 29: Are hospital readmissions in the elderly preventable? Antonio Sarría-Santamera MD PhD Institute of Health Carlos III University of Alcalá DUKE-NUS HSSR

• Interventions with many components, involving more individuals in care delivery, and supporting patient capacity for self-care.

• Leppin AL. JAMA Intern Med. 2014 Jul;174(7):1095-107

Page 30: Are hospital readmissions in the elderly preventable? Antonio Sarría-Santamera MD PhD Institute of Health Carlos III University of Alcalá DUKE-NUS HSSR

• Home or community care of patients led to a significant reduction of readmissions.

• Benbassat. Israel Journal of Health Policy Research 2013, 2:1

Page 31: Are hospital readmissions in the elderly preventable? Antonio Sarría-Santamera MD PhD Institute of Health Carlos III University of Alcalá DUKE-NUS HSSR

QUALITATIVE STUDY

Page 32: Are hospital readmissions in the elderly preventable? Antonio Sarría-Santamera MD PhD Institute of Health Carlos III University of Alcalá DUKE-NUS HSSR

Qualitative study: problems• No formal communication between PC and hospitals• EMR in PC is connected with EMR in hospitals, but there is no

information PC receive when a patient is admitted to the hospital• Information from patients when they are discharged• Patients have new medicines prescribed• PC have to reevaluate patients based on the new information• Believe that at the hospital there is a view of hospitalizations as

acute events, not as a manifestation of the continuous process of losing functional capacity

• There is the possibility of home visits, but the lack of communication limits an appropriate scheduling

• Continuity of care of a continuous process limited by this communication barrier

Page 33: Are hospital readmissions in the elderly preventable? Antonio Sarría-Santamera MD PhD Institute of Health Carlos III University of Alcalá DUKE-NUS HSSR

Qualitative study: proposals

• Individualize care to specific patient situation• Improve opportunities for home care• Self-management• Coordinated and shared care between PC-

hospitals

Page 34: Are hospital readmissions in the elderly preventable? Antonio Sarría-Santamera MD PhD Institute of Health Carlos III University of Alcalá DUKE-NUS HSSR

COMMENTS

Page 35: Are hospital readmissions in the elderly preventable? Antonio Sarría-Santamera MD PhD Institute of Health Carlos III University of Alcalá DUKE-NUS HSSR
Page 36: Are hospital readmissions in the elderly preventable? Antonio Sarría-Santamera MD PhD Institute of Health Carlos III University of Alcalá DUKE-NUS HSSR

Questions

• Are hospital readmissions in the elderly preventable?

• Hospital readmissions measure hospital quality?

• Do we really know the “natural history” of the disabilitating process related with the advancement of chronic conditions?

Page 37: Are hospital readmissions in the elderly preventable? Antonio Sarría-Santamera MD PhD Institute of Health Carlos III University of Alcalá DUKE-NUS HSSR

Are readmissions preventable?Systematic review

Page 38: Are hospital readmissions in the elderly preventable? Antonio Sarría-Santamera MD PhD Institute of Health Carlos III University of Alcalá DUKE-NUS HSSR

Complex interventions MRC

• Difficulty of standardizing the design and delivery of the interventions.

• Sensitivity to features of the local context.• Organizational and logistical difficulty of

applying experimental methods to service or policy change.

• Length and complexity of the causal chains linking intervention with outcome.

Page 39: Are hospital readmissions in the elderly preventable? Antonio Sarría-Santamera MD PhD Institute of Health Carlos III University of Alcalá DUKE-NUS HSSR

CONCLUSIONS

• Increased risk of readmission:– Short term:

1. Number of previous hospital admissions2. Length of stay

– Long term:1. Multi-morbidity/poly-pharmacy2. Functional capacity3. Social factors

• Effective preventive interventions:1. Coordination hospital-PC2. Home care component3. Self-management

Page 40: Are hospital readmissions in the elderly preventable? Antonio Sarría-Santamera MD PhD Institute of Health Carlos III University of Alcalá DUKE-NUS HSSR

Systemic perspective

• The process of care can not be fragmented into different to some extent independent components.

• Most of the factors associated with a higher risk of readmission require to take into consideration a broad systemic approach.

• The specific characteristics of how to resolve this problem are yet to be understood