Electronic Supplementary Information (ESI)

1

Figure S1: Fabrication process using the desktop digital plotter/cutter and technical drawing pen

with custom refillable ink and Functional test of PADs using BSA as tested bioanalyte: a) Pattern

drawing using a software controlled plotter/cutter. Insertion pictures show a holder for technical

drawing pen or blade for cutting function, b) an image of the fabricated PADs featuring eight

reservoirs and c) quantitative assay of BSA using BPB as binding probe to form blue colour complex.

2

Table S1 Measurements of the phenolic compounds, flavonoids and DPPH• free radical scavenging activity in beverage samples using the µPADs and

spectrophometric assay

3

Beverage Total phenols

(mg GAE/g (L) of sample ± SD)

Total flavonoids

(mg QE/g (L) of sample ± SD)

DPPH• free radical scavenging activity

(BHT equivalent/ g (L) of sample ± SD)

µPADs Spectrophotometry µPADs Spectrophotometry µPADs Spectrophotometry

Tea 1 112.50.4 120.40.2 20.20.8 27.50.7 8.00.9 12.70.8

Tea 2 107.10.5 114.90.8 12.31.0 16.80.4 5.91.9 8.11.2

Tea 3 90.91.4 95.61.1 11.11.2 16.30.5 6.51.3 9.91.0

Tea 4 77.41.1 85.60.7 7.21.1 13. 51.1 5.51.0 7.80.8

Wine 1 244.31.6 250.10.9 72.41.2 79.80.6 7.41.0 10.00.6

Wine 2 157.90.7 160.40.7 65.41.0 70.60.5 6.71.8 10.21.3

Beer 108.30.8 114.60.4 46.20.9 50.80.8 5.02.0 6.11.0