Supplementary material

Table. Total phenolic compounds, caffeoylquinic acids and flavonoids content in yerba-mate (Ilex paraguariensis) leaves and commercial products.

SourceTotal Phenolic compounds (1)

(g /100g)

Caffeoylquinic acids (2) (mg/g) Di-Caffeoylquinic acids (2) (mg/g) Rutin (2)

(mg/g)References

3-CQA 5-CQA 4-CQA 3,4-DCQ 3,5-DCQ 4,5-DCQ

Dried leaves 9.61 u.q. (3) 28.0 ± 3.0 u.q. 8.6 ± 0.6 30.4 ± 1.8 28.9 ± 0.6 0.6 ± 0.05(Filip, López, Gilberti,

Coussio, & Ferraro, 2001)

Dried leaves u.q. u.q. 13.67 ± 3.62 u.q. u.q. u.q. u.q. u.q.(Bastos, Fornari,

Queiroz, & Torres, 2006)

Dried leaves 8.75 ± 0.22 u.q. 8.76 ± 2.31 u.q. u.q. u.q. u.q. u.q. (Cardozo Junior et al., 2007)

Dried leaves 11.1 u.q. u.q. u.q. u.q. 20.0 5.0 u.q. (Schinella et al., 2009)

Dried leaves u.q. 11.94 ± 0.44 11.45 ± 0.33 13.73 ± 0.30 u.q. u.q. u.q. 3.75 ± 0.39 (Dartora et al., 2011)

Dried leaves 8.03 24.09 16.12 11.01 23.17 5.89 u.q. u.q. (Balzan et al., 2013)

Commercial mate (4) 7.94 ± 0.25 45.22 ± 2.14 (5) 31.77 ± 1.76 (6) 4.86 ± 0.14 (Bravo et al., 2007)

Commercial mate u.q. u.q. 8.74 ± 0.69 u.q. u.q. u.q. u.q. u.q. (Rivelli et al., 2007)

Commercial mate u.q. u.q. 9.75 ± 0.17 u.q. u.q. u.q. u.q. u.q. (Streit et al., 2007)

Commercial mate 4.78 ± 0.29 u.q. u.q. u.q. u.q. u.q. u.q. u.q. (Meinhart et al., 2010)

(1) Quantified using Folin–Ciocalteau reagent; (2) Quantified by HPLC; (3) u.q. = unquantified; (4) Commercial mate (70% dried leaves + 30% branches); (5) (∑ =Caffeoylquinic acids); (6) (∑ =Di- and Tri-caffeoylquinic acids).

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Table. Phenolic compounds present in mate (Ilex paraguariensis) products characterized by

LC/MS.

Compound * Denomination/Abbreviation

Phenolic acids3-O-caffeoylquinic acid Neo-chlorogenic acid (3-CQA)

Dicaffeic acidDicaffeic acid

Coumaroylquinic acid (CoQA)5-O-caffeoylquinic acid Chlorogenic acid (5-CQA)

4-O-caffeoylquinic acid Crypto-chlorogenic acid (4-CQA)Caffeoylquinic acid (1-CQA)

Feruloylquinic acid (3-FQA)Feruloylquinic acid (5-FQA)

Feruloylquinic acid (4-FQA)Caffeoylshikimic acid

3,4-Dicaffeoylquinic acid (3,4-di-CQA)3,5-Dicaffeoylquinic acid (3,5-di-CQA)

4,5-Dicaffeoylquinic acid (4,5-di-CQA)Caffeoylferuloylquinic acid (3F, 4C-QA)

Dicaffeoylquinic acid (1,5-di-CQA)Caffeoylcoumaroylquinic acid (CCoQA)

Caffeoylsinapylquinic acid (CSQA)Caffeoylferuloylquinic acid (3C,4F-QA)

Caffeoylferuloylquinic acid (3F, 5C-QA)Caffeoylferuloylquinic acid (4C, 5F-QA)

Tricaffeoylquinic acid (tri-CQA)Flavonoids

Quercetin-3-O-glycoside (hexoside) IsoquercitinQuercetin-3-arabinoside Guaijaverin

Quercetin-3-O-rhamnoside QuercitrinQuercetin-3-O-rutinoside Rutin

Kaempferol-3-O-rhamnoglucoside

Kaempferol-3-O-glycoside* Ref.: (Bravo et al., 2007; Carini, Facino, Aldini, Calloni, & Colombo, 1998; Dartora et al., 2011; Dugo et al., 2009; Souza et al.,

2011).

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