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PharmacoEconomics & Outcomes News 652 - 28 Apr 2012
ASCO’s "top five" costly overusedinterventions
ASCO* has identified the top five cancer practices orinterventions that are "costly, widely used, and notsupported by high-level clinical evidence", according toan article published in the Journal of Clinical Oncology.ASCO say that these interventions should not beadministered unless careful consideration has beengiven to the appropriateness of use in individual cases.The top five are:• cancer-directed therapy for solid tumours in patients
with low performance status (III or IV), not eligiblefor a clinical trial, with no benefit from priorevidence-based interventions or with no strongevidence supporting the clinical value of furthertreatment
• PET**, computed tomography (CT) or radionuclidebone scans (RBS) for staging of early prostate cancerin men at low risk of metastases
• PET, CT or RBS for the staging of early breast cancerin women at low risk of metastases
• surveillance biomarker testing or imaging (PET, CTor RBC) in asymptomatic breast cancer patientspreviously treated with curative intent
• white cell stimulating factors for the primaryprevention of febrile neutropenia in patients with a< 20% risk.
The authors say that reconsidering the use of thesefive interventions "one patient at a time" is likely to"improve the value of care" provided at the "lowest costto the patient and society".* American Society of Clinical Oncology** positron emission tomography
Schnipper LE, et al. American Society of Clinical Oncology Identifies Five KeyOpportunities to Improve Care and Reduce Costs: The Top Five List for Oncology.Journal of Clinical Oncology : 3 Apr 2012. Available from: URL: http://dx.doi.org/10.1200/jco.2012.42.8375 803069566
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PharmacoEconomics & Outcomes News 28 Apr 2012 No. 6521173-5503/10/0652-0001/$14.95 Adis © 2010 Springer International Publishing AG. All rights reserved