1Acute intermittent hypoxia augments the cardiovascular response to an orthostatic challenge preceded by locomotor exercise.Wednesday, May 02, 2018 09:30 AM - 10:30 AMLearning Objectives:Provide a characterization of the additive effects of acute exercise and intermittent hypoxia on cardiovascular response to orthostatic challenge.

Participants:McMillan D, Maher J, Nash MUniversity of Miami , Coral Gables , FL, United statesDavid McMillan, MSUniversity of Miami Bio:David W McMillan, MS, is a doctoral candidate in the clinical exercise physiology PhD program at the University of Miami's, and a graduate research assistant at The Miami Project to Cure Paralysis. He began administering exercise therapy to people with spinal cord injuries (SCI) during his Bachelor's training, and conducted a Master's thesis pertaining to the topic of optimization of neuromuscular responses to acute locomotor exercise in persons with SCI. He now works with Drs. Mark S Nash and Kevin A Jacobs studying cardiovascular and metabolic responses to lifestyle interventions in this population. His global research interest relate to the role of the central nervous system in control energy expenditure and macronutrient processing, and he is conducting a dissertation project examining the effect of acute exercise on dietary lipid metabolism.Education:California State University San Marcos (San Marcos, CA), BS 2009 - 2013, Exercise Science

California State University Los Angeles (Los Angeles, CA), MS 2013 - 2015, Exercise Science

University of Miami (Miami, FL), PhD 2015 - Current, Clinical Exercise PhysiologyThis author has no relevant disclosures.Jennifer Maher, PhDUniversity of Miami This author has no relevant disclosures.Mark Nash, PhDUniversity of Miami This author has no relevant disclosures.

2Talking in Private: Facebook Closed Group Promotes SCI Peer SupportWednesday, May 02, 2018 09:30 AM - 10:30 AMLearning Objectives:

Describe how a Facebook closed group can provide a peer support community for people coping with spinal cord injuries

Participants:1Flaum T, 2Lollino S1Hill Foundation for Families Living with Disabilities , Chicago , IL, United states; 2Hill Foundation for Families Living with Disabilitiess , Chicago , IL, USAThea Flaum, BAHill Foundation for Families Living with Disabilities Bio:Thea Flaum is the president of the Hill Foundation for Families Living with Disabilities. She is the founder of FacingDisability.com, an innovative website which provides information and support for families facing spinal cord injuries. She oversees all activities of the website and the Foundation. She comes to this work after a 35-year career as a television producer. She is currently a member of the boards of Chicago's Shirley Ryan AbilityLab (formerly the Rehabilitation Institute of Chicago), Access Living of Metropolitan Chicago, the National Advisory Board of the Model Systems Knowledge Translation Center, and the Advisory Board of the Midwest Regional Spinal Care Injury System (Shirley Ryan AbilityLab) with which she is currently developing a series of spinal cord injury videos for the in-hospital TV systems of all Model Systems hospitals. Education:BA 1960--English Honors Skidmore College, Saratoga Spring, NYThis author has no relevant disclosures.Stephanie Lollino, B.AHill Foundation for Families Living with Disabilitiess Bio:Stephanie D. Lollino, Executive Producer of FacingDisability.com, is a Chicago native who has been working with the website since its inception. She received her BA in Journalism from Winona State University in Minnesota and became a corporate video producer and TV producer for major national television networks. Her background in research, media and writing is career-long. After spending 20 years as a producer and writer, she began working with The Hill Foundation in 2014, which supports FacingDisability.com. Since she has been with the company, Stephanie has helped shape the video content of the website and to build a successful and growing social media presence which is crucial to people with spinal cord injuries and their families. She is a member of the Advisory Board of the Midwest Regional Spinal Care Injury System (Shirley Ryan AbilityLab) with which she is currently developing a series of spinal cord injury videos for the in-hospital TV systems of all Model Systems hospitals.

Her extensive background in bringing people and their stories together through creative communication turns the task of improving the lives of others a dream job. “Making people aware of SCI, and everything that goes along with it, is something I am really proud to do.”

Stephanie enjoys outdoor sports and fitness – especially with her two daughters and husband of 15 years.

Education:B.A. Journalism 1995

Winona State University Winona, MNThis author has no relevant disclosures.

3An acute bout of body-weight support treadmill training improves blood glucose control in obese men with incomplete spinal cord injuries: A case seriesWednesday, May 02, 2018 09:30 AM - 10:30 AM

Participants:1Maher J, 1Nash M, 2Mendez A1The Miami Project to Cure Paralysis , Miami , FL, USA; 2The Diabetes Research Institute , Miami , FL, USAJennifer Maher, PhDThe Miami Project to Cure Paralysis Bio:Jennifer L. Maher, PhD is a postdoctoral associate at the Miami Project to Cure Paralysis. After receiving her Bachelor's and Master's degrees in exercise science from the University of Florida and University of West Florida, respectively, Maher completed her doctorate in Exercise Physiology with a focus in human energy metabolism at the University of Miami. For her postdoctoral training she is currently working under the mentorship of Mark S. Nash investigating cardiometabolic responses to exercise after spinal cord injury (SCI). She has established a line of research developing novel strategies that aim to restore functional independence in individuals with SCI and prevent secondary complications while also attempting to better understand the underlying physiological mechanisms. Education:Education: 2013 University of Miami Exercise Physiology Ph.D. 2004 University of West Florida Exercise Science M.S. 2003 University of Florida Exercise and Sport Science B.S. This author has the following disclosures:Mark Nash, PhDThe Miami Project to Cure Paralysis This author has the following disclosures:Armando Mendez, PhDThe Diabetes Research Institute This author has the following disclosures:

4Spinal cord atrophy after spinal cord injury, a meta-analysis and replication.

Wednesday, May 02, 2018 09:30 AM - 10:30 AMLearning Objectives:Understanding the magnitude of above-lesion cord atrophy, and how it can be measured using MRI

Participants:1Linnman C, 2Dahlberg L, 3Morse L1Boston Children's Hospital and Spaulding Rehab Hospital , Boston , MA, USA; 2Boston Children's Hospital , Boston , MA, USA; 3Craig Hospital , Denver , CO, USAClas Linnman, PhDBoston Children's Hospital and Spaulding Rehab Hospital Bio:Clas Linnman, PhD, is an assistant professor in Anesthesia at Boton Children's Hospital and and associate in Research at Spaulding Rehab Hospital. He studies the role of neuroinflammation and microglia in neuropathic pain after spinal cord injury using Positron Emission Tomography and Magnetic Resonance Imaging, employing both clinical studied and animal models. Education:PhD, Psychology, Uppsala University, Sweden, 2008This author has no relevant disclosures.Linda Dahlberg, PhDBoston Children's Hospital This author has no relevant disclosures.Leslie Morse, DOCraig Hospital This author has no relevant disclosures.

5Regenerating axons and blood vessels in tissue engineered scaffolds have defined spatial relationships after complete spinal cord injury in rats.Wednesday, May 02, 2018 09:30 AM - 10:30 AMLearning Objectives:Identify the distribution patterns and defined relationships of tissue-engineered, regenerating axons and blood vessels after complete spinal cord injury.

Participants:1Madigan N, 2Oswald D, 3Kelly D, 1Hakim J, 1Chen B, 1Yaszemski M, 1Windebank A1Mayo Clinic , Rochester , Minnesota, USA; 2Paracelsus Medical University , Salzburg , , Austria; 3National University of Ireland, Galway (Nuig) , Galway , , IrelandNicolas Madigan, MB BCh BAO, PhDMayo Clinic Bio:Dr. Nicolas Madigan completed clinical residency training in Internal Medicine in Ireland and in Neurology at the Mayo Clinic. He has worked in the Neural Regeneration spinal cord injury

research group for the last ten years as a research fellow and in an international collaboration with Galway, Ireland. Dr. Madigan recently completed a three year a post-doctoral research fellowship in the Clinical Investigator Program in Translational Research for Regenerative Medicine at Mayo Clinic. He was funded in part as NIH T32 Fellow for Regenerative and Translational Medicine. Dr. Madigan is now training in Mayo Clinic's Neuromuscular Medicine fellowship. His research research has involved the use of Schwann cells and mesenchymal stem cell as therapies for spinal cord injury. He have developed a series of genetically modified stem cell lines for neurotrophic growth factor delivery to the injured spinal cord in animals implanted with hydrogel scaffolds. Dr. Madigan is involved as a Co-Investigator in three clinical trials at Mayo Clinic using intrathecal delivery of autologous MSC to patients with spinal cord injury and ALS. His role extends from direct patient care in the hospital and outpatient clinic to both develop the next generation of therapeutic cell lines and polymer cell delivery for spinal cord injury repair. The patient-centered design is a highly collaborative approach, focused on safety and efficient current Good Manufacturing Practices, for rapid clinical translation of a novel treatment for spinal cord injury patients. Education:National University of Ireland, Galway, MB BCh BAO 1999 - 2004 Medicine, Surgery and Obstetrics University College Hospital, Galway, Ireland. 2004-2007 Internal Medicine Residency National University of Ireland, Galway, PhD 2007 - 2012 Mayo Clinic, Rochester MN 2010-2014 Neurology Residency Rutgers The State University of New Jersey, New Brunswick, New Jersey - 2014 - 2016 NIH T-32 Fellow, Regenerative and Translational Medicine Mayo Clinic, Rochester MN 2014-2017 Fellow, Clinician-Investigator Program Mayo Clinic, Rochester MN 2017 - present, Fellow, Neuromuscular MedicineThis author has the following disclosures:

Other (see below)Stipend support from Mayo Clinic Graduate School of Medical EducationDavid Oswald, MDParacelsus Medical University This author has no relevant disclosures.Domhnall Kelly, MScNational University of Ireland, Galway (Nuig) This author has no relevant disclosures.Jeffery Hakim, MD, PhDMayo Clinic This author has no relevant disclosures.Bingkun Chen, MD, PhDMayo Clinic This author has no relevant disclosures.Michael Yaszemski, MD, PhDMayo Clinic This author has the following disclosures:

Research Support

Other (see below)R01 NIH/NIBIB; R01 NIH/NIAMS; Department of Defense/Armed Forces Institute of Regenerative Medicine Patent held on OPF polymer materialsAnthony Windebank, MDMayo Clinic This author has the following disclosures:

Research SupportNational Institute of Aging; National Center for Advancing Translational Sciences; Armed Forces Institute of Regenerative Medicine; Regenerative Medicine Minnesota; Morton Cure Paralysis Fund; Craig H. Neilsen Foundation; The Bowen Family Foundation; The Judith and Jean Pape Adams Foundationl Mayo Clinic Center for Regenerative Medicine; and BrainStorm Cell Therapeutics

6Metabolic dysfunction exacerbates astrogliosis and impairs motor recovery after experimental spinal cord injuryWednesday, May 02, 2018 09:30 AM - 10:30 AMLearning Objectives:Define the impact of systemic metabolic dysfunction on neurobehavioral recovery following traumatic spinal cord injury.

Participants:Kim H, Yoon H, Kleven A, Kleppe L, Lanza L, LeBrasseur N, Matveyenko A, Scarisbrick IMayo Clinic , Rochester , MN, United statesHaneui Kim, Mayo Clinic Bio:Ha Neui Kim, PhD, is a research fellow in Dr. Scarisbrick lab and the department of physical medicine and rehabilitation in Mayo Clinic. After receiving her Bachelor’s in biology from Kyung Sung University in South Korea in 2009, and she moved to Pusan National University of Korean Medicine to study Korean medicine and neuroscience and earned her Master’s and Doctoral (Korean Medicine and neuroscience) degree in 2014. She performed two years post-doctoral research fellow at same university as earned PhD degree and then started third year of research fellow in physical medicine and rehabilitation in Mayo Clinic, Rochester Minnesota from 2016 so far. She studies electroacupuncture and herbal medicine for pain and cerebral palsy, rehabilitation in animal model and protease-activated receptor-1 inhibitor for multiple sclerosis. Now she have been studying metabolic dysfunction and protease activated receptors deletion model with spinal cord injury for moto recovery and rehabilitation. Education:Kyung Sung University (Busan, South Korea), BS 2005-2009 Biology

Pusan National University School of Korean medicine (Yangsan-si, Gyeongsangnam-do, South Korea), MS 2009-2011, Korean medicine

Pusan National University School of Korean medicine (Yangsan-si, Gyeongsangnam-do, South Korea), PhD 2011-2014, Korean medicine

Pusan National University School of Korean medicine (Yangsan-si, Gyeongsangnam-do, South Korea), Postdoctoral research fellow 2014-2016, Neuroscience

Mayo Clinic (Rochester, MN) Research Fellow, 2016-present, Physical Medicine and RehabilitationThis author has no relevant disclosures.Hyesook Yoon, PhDMayo Clinic This author has no relevant disclosures.Andrew Kleven, PhDMayo Clinic This author has no relevant disclosures.Laurel Kleppe, Mayo Clinic This author has no relevant disclosures.Lan Lanza, PhDMayo Clinic This author has no relevant disclosures.Nathan LeBrasseur, PhDMayo Clinic This author has no relevant disclosures.Aleksey Matveyenko, PhDMayo Clinic This author has no relevant disclosures.Isobel Scarisbrick, PhDMayo Clinic This author has no relevant disclosures.

7Accelerated Cardiometabolic Risks and Extant Atherosclerotic Disease in a Model of Spinal Cord InjuryWednesday, May 02, 2018 09:30 AM - 10:30 AMLearning Objectives:Illustrate that spinal cord injury exacerbates extant atherosclerotic disease and discuss the effect of anti-inflammatory pharmacotherapy on disease severity

Participants:1Bigford G, 2Herderick E, 1Mendez A, 1Nash M

1University of Miami Miller School of Medicine , Miami , FL, USA; 2Eeh Science Llc , Pickerington , OH, USAGregory Bigford, PhDUniversity of Miami Miller School of Medicine Bio:Our research examines how trauma to the central nervous system triggers chronically acquired secondary diseases such as cardiovascular disease and diabetes. The aim is to understand how metabolic dysfunction contributes to these disease states on a cellular, physiological and behavior level. Our overall goal is to test interventions directed at minimizes dysfunction and disease due to CNS trauma.Education:University of Miami Miller School of Medicine, PhD 2009, Neuroscience University of Toronto, BS 2001, KinesiologyThis author has no relevant disclosures.Edward Herderick, Eeh Science Llc This author has the following disclosures:

ConsultantEEH Science LLC; analystArmando Mendez, PhDUniversity of Miami Miller School of Medicine This author has no relevant disclosures.Mark Nash, PhDUniversity of Miami Miller School of Medicine This author has no relevant disclosures.

8Factors associated with regular dental care in people with spinal cord injury: Results from the FRASCI studyWednesday, May 02, 2018 09:30 AM - 10:30 AMLearning Objectives:Attendees will learn factors that are related to receiving regular dental care in people with spinal cord injury.

Participants:1Coker J, 1Morse L, 2Battaglino R1Craig Hospital , Englewood , CO, US; 2University of Colorado - Anschutz Medical Campus , Aurora , CO, USJennifer Coker, MPHCraig Hospital Bio:Ms. Coker has worked in the field of traumatic spinal cord injury (SCI) since 1997. She obtained a Master of Public Health from the Rollins School of Public Health at Emory University in May

2001, where she won the James W Alley Award for Outstanding Service to Disadvantaged Populations, and is currently a PhD student in the Clinical Sciences program at the University of Colorado-Anschutz Medical Campus. She has presented research at national conferences of ASIA, the American Association of Spinal Cord Injury Psychologists and Social Workers (now ASCIP), the American Public Health Association, and the American Psychological Association. In addition, Ms. Coker has won several awards for research presentations and publications. She has been a Research Associate at Craig Hospital since April 2012 and works primarily with the SCI Model Systems (SCIMS) projects. Ms. Coker is the PI for the Craig H Neilsen Foundation funded project, A Bridge from Rehabilitation to Real-World: Reinventing Yourself after SCI, the SCIMS module, Utilization of Complementary and Integrative Healthcare to Treat Pain in People with SCI, and Co-PI for a NIDILRR-funded project, A Multi-site Randomized Controlled Trial of an Intervention to Improve Outcomes after Spinal Cord Injury.Education:Berry College (Mt Berry, GA), BA 1997, Psychology & Child Development

Rollins School of Public Health, Emory University (Atlanta, GA), MPH 2001, Behavioral Health & Education

Clinical Science Graduate Program, University of Colorado-Anschutz Medical Campus (Aurora, CO), PhD in progress, Clinical Investigations This author has the following disclosures:

Research Support Other (see below)

Research Support: National Institute on Disability, Independent Living, and Rehabilitation Research (90SI5015).

Other-Employment: Craig Hospital, Englewood, CO; Medical University of South Carolina, Charleston, SC

Other-Volunteer: Cycle of Hope Board of Directors (member)Leslie Morse, DOCraig Hospital This author has the following disclosures:

Research Support Other (see below)

Research Support: National Institute of Child Health and Human Development (R21HD057030 and R21HD057030‐ 02S1), National Institute of Arthritis and Musculoskeletal and Skin Diseases (1R01AR059270‐01), and National Institute on Disability, Independent Living, and Rehabilitation Research (90SI5015).

Other-Employment: Craig Hospital, Englewood, CORicardo Battaglino, PhDUniversity of Colorado - Anschutz Medical Campus This author has the following disclosures:

Research Support Other (see below)

Research Support: National Institute of Child Health and Human Development (R21HD057030 and R21HD057030‐ 02S1), National Institute of Arthritis and Musculoskeletal and Skin Diseases (1R01AR059270‐01)

Other-Employment: University of Colorado-Anschutz, Aurora, CO

9Heritability in spinal cord thickness – a twin studyWednesday, May 02, 2018 09:30 AM - 10:30 AMLearning Objectives:Learning objective: To discuss how heritability may contribute to variability in cervical spinal cord thickness, a metric that is a proxy of above-lesion spinal cord degeneration.

Participants:Solstrand Dahlberg LBoston Children's Hospital, Harvard Medical School , Boston , MA, USALinda Solstrand Dahlberg, PhDBoston Children's Hospital, Harvard Medical School Bio:Linda Solstrand Dahlberg, PhD, is a research fellow in the department of Anesthesiology, Perioperative and Pain Medicine at Boston Children's Hospital. She studies the role of neuroinflammation and microglia in neuropathic pain after spinal cord injury using Positron Emission Tomography and Magnetic Resonance Imaging, employing both clinical studies and animal models. Lately she has also focused on spinal cord structure as a metric in relation to injury and behavior. Her background is in neuroscience and neuroimaging. Education:Education Uppsala University, Uppsala, Sweden PhD Neuroscience 2012-2015 Project title: Relationship between psychiatric condition, feeding behaviour, neuropathology and the structure of the adolescent brain.

University of Nottingham, Nottingham, UK MSc Cognitive Neuroscience and Neuroimaging 2010-2011 Main modules: Methods for Cognitive Neuroscience, Advanced Statistics Course, Neuroimaging Practicals.

University of Nottingham, Nottingham, UK BSc (Hons) Psychology 2007-2010

Main modules: Cognitive Psychology, Behavioral Psychology and Neuroscience, Statistical Methods in Psychology and Social Psychology. This author has no relevant disclosures.

10Brain White Matter Abnormality Induced by Chronic Spinal Cord Injury in the Pediatric Population: A Tract Based Spatial Statistic StudyWednesday, May 02, 2018 09:30 AM - 10:30 AMLearning Objectives:Discuss how the severity of spinal cord injury can lead to white matter changes in the cerebral cortex using TBSS.

Participants:Krisa L, Middleton D, Alizadeh M, Fisher J, Calhoun-Thielen C, Mulcahey M, Mohamed FThomas Jefferson University , Philadelphia , Pennsylvan, United statesLaura Krisa, PhDThomas Jefferson University Bio:Laura Krisa, PhD is an Assistant Professor in the departments of Physical and Occupational therapy at Thomas Jefferson University. After receiving a bachelors degree in biology she earned her PhD in Neuroscience from Drexel University College of Medicine. Laura’s research focus is using advanced imaging techniques, including functional Magnetic Resonance Imaging (fMRI) and Diffusion Tensor Imaging (DTI) as potential biomarkers in persons with spinal cord injury. Her recent work has indicated positive findings in using these techniques in conjunction with the clinical exam to further define injury location and severity. Education:INSTITUTION AND LOCATION DEGREE (if applicable)

Completion Date MM/YYYY

FIELD OF STUDY

Millersville University, Millersville, PA B.S. 05/04

Biology

Drexel University, Philadelphia, PA Ph.D. 05/10

Neuroscience

Shriners Hospitals for Children, Philadelphia, PA Post-Doctoral Fellowship 03/13 Clinical Neuroscience This author has the following disclosures:

Research SupportDevon Middleton, PhDThomas Jefferson University This author has no relevant disclosures.Mahdi Alizadeh, PhDThomas Jefferson University This author has no relevant disclosures.Joshua Fisher, BSThomas Jefferson University This author has no relevant disclosures.Christina Calhoun-Thielen, MS/PTThomas Jefferson University This author has no relevant disclosures.MJ Mulcahey, OT, PhDThomas Jefferson University This author has no relevant disclosures.Feroze Mohamed, PhDThomas Jefferson University This author has no relevant disclosures.

11Extent and pattern of lower motor neuron damage following cervical spinal cord injuryWednesday, May 02, 2018 09:30 AM - 10:30 AMLearning Objectives:Learn about the pattern of lower motoneuron damage following traumatic/ischemic cervical spinal cord injury, and its potential impact on the application of innovative therapeutic approaches such as spinal neuroregenerative strategies or upper extremity neuroprostheses.

Participants:Franz S, Eck U, Wolf M, Wilder-Smith E, Weber M, Rupp R, Weidner NHeidelberg University Hospital , Heidelberg , , Germany

Steffen Franz, MDHeidelberg University Hospital Bio:Academic activities / Teaching Since 10/2014 Lecturer at the Spinal Cord Injury Center, Heidelberg University Hospital: • Focus areas: o Courses in neurological examination o Courses in physical and rehabilitative medicine, with specific focus on spinal cord injury care. o Tutor for undergraduate students attending clinical traineeships and internships in neurology and spinal cord medicine. Since 05/2010 Consulting physician and instructor for the official “European Multicenter Study about Spinal Cord Injury (EMSCI)” training course: “Neurological examination according to the International Standards for Neurological Classification in Spinal Cord Injury (ISNCSCI) of the American Spinal Injury Association (ASIA)”. Focus of research activities Regeneration and neuroplasticity of the central nervous system • Current focus: Functional and structural plasticity following spinal cord injury: contributions to chronic central neuropathic pain. (SFB1158 of the German Research Foundation [DFG]: https://www.sfb1158.de) Neurorehabilitation: • Neuroprosthetics • Functional and therapeutic electric stimulation • Electrode-nerve-interfaces Clinical and neurophysiological measurements, assessments and outcomes Board memberships, committees and society memberships: Since 2017 • Member of the "Education Committee" of the American Spinal Injury Association (ASIA) Since 2016 • Editorial board working on the clinical guidelines for pain after spinal cord injury by order of the German speaking medical society for paraplegia (DMGP). Perpetual • German Society for Neurology (DGN) • International Spinal Cord Society (ISCoS) • American Spinal Injury Association (ASIA) • Deutschsprachige Medizinische Gesellschaft für Paraplegiologie (DMGP) Awards 2015 Friedrich-Wilhelm Meinecke – memorial award – of the DMGP Publications Original work, reviews and case reports Franz S, Schuld C, Wilder-Smith EP, Heutehaus L, Lang S, Gantz S,

Schuh-Hofer S, Treede RD, Bryce TN, Wang H, Weidner N. (2017) Spinal Cord Injury Pain Instrument and painDETECT questionnaire: Convergent construct validity in individuals with Spinal Cord Injury. Eur J Pain 2017. Schuld C, Franz S, Bruggemann K, Heutehaus L, Weidner N, Kirshblum SC, Rupp R, EMSCI study group. (2016) International standards for neurological classification of spinal cord injury: impact of the revised worksheet (revision 02/13) on classification performance. The journal of spinal cord medicine 2016:1-9. Franz S, Kirshblum SC, Weidner N, Rupp R, Schuld C & on behalf of the EMSCI study group (2016) Motor levels in high cervical spinal cord injuries: Implications for the International Standards for Neurological Classification of Spinal Cord Injury, J Spinal Cord Med. 2016 Feb 25. Schuld C, Franz S, van Hedel HJ, Moosburger J, Maier D, Abel R, van de Meent, H., Curt, A., Weidner, N., Emsci study group, Rupp, R. et al. (2014) International standards for neurological classification of spinal cord injury: classification skills of clinicians versus computational algorithms. Spinal cord. 2014 Dec 9. PubMed PMID: 25487243. Franz S, Ciatipis M, Pfeifer K, Kierdorf B, Sandner B, Bogdahn U, Blesch A, Winner B, Weidner N (2014). Thoracic Rat Spinal Cord Contusion Injury Induces Remote Spinal Gliogenesis but Not Neurogenesis or Gliogenesis in the Brain. PloS one 9: e102896 Schuld, C., Wiese, J., Franz, S., Putz, C., Stierle, I., Smoor, I., Weidner, N., and Rupp, R. (2013). Effect of formal training in scaling, scoring and classification of the International Standards for Neurological Classification of Spinal Cord Injury. Spinal cord 51, 282-288. Franz, S., Weidner, N., and Blesch, A. (2012). Gene therapy approaches to enhancing plasticity and regeneration after spinal cord injury. Experimental neurology 235, 62-69. Grum, F., Hufendiek, K., Franz, S., Bogdahn, U., Gamulescu, M.A., Rummele, P., and Schlachetzki, F. (2010). High-resolution color-coded sonography in angiolymphoid hyperplasia with eosinophilia presenting as temporal arteritis. Circulation 121, 1045-1046. Anneser, J.M.H., Chahli, C., Franz, S., Borasio, G.D., Lorenzl S. (2007) Die Regulation entzündlicher Prozesse bei der Amyotrophen Lateralsklerose: Suppressor of cytokine signalling, aktiviertes STAT und CCAAT/enhancer-binding protein ß (c/EBP ß) Aktuelle Neurologie 01/2007; 34. Book chapters Franz S., Finnerup N.B. (2017) Diagnostics and therapy of pain in spinal cord injury. In: Neurological Aspects of Spinal Cord Injury, ed. K. Tansey, R. Rupp, N. Weidner. Heidelberg: Springer. DOI: 10.1007/978-3-319-46293-6_12 Franz S., Hug A., Weidner N. (2015) Functional Recovery in CNS disease: Impact of animal models. In: Oxford Textbook of Neurorehabilitation, ed. V. Dietz, N. Ward. DOI:10.1093/med/9780199673711.003.0011 Heidelberg, Germany, October 5, 2017

Education:Education and Qualification Since 01/2014 Consultant Neurologist (attending physician) at the Spinal Cord Injury Center, Heidelberg University Hospital 03/2013 – 12/2013 Neurologist and Postdoctoral Fellow – Spinal Cord Injury Center, Heidelberg University Hospital 03/2013 Board Certification in Neurology 10/2012 – 02/2013 Registrar/Resident and Postdoctoral Fellow – Spinal Cord Injury Center, Heidelberg University Hospital 10/2011 – 09/2012 Registrar/Resident – Department of Psychiatry, Heidelberg University Hospital 01/2011 – 09/2011 Registrar/Resident and Postdoctoral Fellow – Spinal Cord Injury Center, Heidelberg University Hospital 12/2009 Board certification/authorisation in application/administration of botulinumtoxin for the indications of spasticity, dystonia, blepharospasm and hemifacial spasm 10/2008 – 12/2009 Associate in “TEMPiS” (tele-medical project for integrated stroke care in Bavaria, Germany) 07/2006 – 12/2010 Registrar/Resident and Graduate/Research Associate – Department of Neurology, University of Regensburg, Germany 10/2001 – 04/2006 Technical University of Munich 3. state examination in April 2006 2. state examination in August 2004 1. state examination in August 2002 Clinical studies in medicine 10/1999 – 09/2001 Ludwig - Maximilians - University of Munich Preliminary medical examination (“Physikum") in August 2001 Preclinical studies in human medicineThis author has no relevant disclosures.Ute Eck, Heidelberg University Hospital This author has no relevant disclosures.Marcel Wolf, Heidelberg University Hospital This author has no relevant disclosures.Einar Wilder-Smith, Heidelberg University Hospital

This author has no relevant disclosures.Marc-André Weber, Heidelberg University Hospital This author has no relevant disclosures.Rüdiger Rupp, Heidelberg University Hospital This author has no relevant disclosures.Norbert Weidner, Heidelberg University Hospital This author has no relevant disclosures.

12Testing the Robustness of “Promising” Neuro-Protective Drug Candidates in a Cervical Hemi-Contusion Model of Rats.Wednesday, May 02, 2018 09:30 AM - 10:30 AMLearning Objectives:XXXXYYYYYXXXXX

Participants:Tetzlaff WIcord , Vancouver , BC, CanadaWolfram Tetzlaff, MD, PhDIcord Bio:XXXXYYYYYYYXXXXXYYYYYEducation:XXXXXYYYYYXXXXXThis author has no relevant disclosures.

13Task specific spinal cord epidural stimulation enables independent stepping in motor complete humansWednesday, May 02, 2018 09:30 AM - 10:30 AMLearning Objectives:Discuss the impact of activity-based, task-specific training on locomotor outcomes after complete spinal cord injury.

Participants:Angeli C, Harkema SUniversity of Louisville , Louisville , KY, USAClaudia Angeli, PhDUniversity of Louisville

Bio:Claudia Angeli, PhD is a Senior Researcher in the Human Locomotion Research Center and Assistant Professor at the Kentucky Spinal Cord Injury Center at the University of Louisville. Dr. Claudia Angeli was born in Buenos Aires, Argentina. After her high school graduation she moved to the United States to further her educational opportunities. She received her B.S. in Health and Human Performance at East Carolina University. From there, she went to Michigan State University where she obtained her Masters and Ph.D. in Kinesiology with a concentration in Mechanical Engineering. While at Michigan State she worked as a research assistant at the Biomechanics Evaluation Laboratory. She moved to Louisville taking a position at Frazier Rehab Institute as the coordinator of the Gait and Biomechanics Laboratory. She also has faculty appointments in the departments of Neurological Surgery, Mechanical Engineering and Physical Medicine and Rehabilitation at the University of Louisville and the department of Physical Therapy at Bellarmine University. Her research interest is in understanding mechanisms of control of human locomotion following neurologic injury. She is working on studies with a primary focus of activity-based retraining of the nervous system following spinal cord injury. Her current work is focused on the use of epidural stimulation in combination with locomotor training to increase the excitability of the spinal cord and augment return of function.Education:1994 B.S. East Carolina University - Exercise and Sport Science.

1996 M.S. Michigan State University Physical Education and Exercise Science. Area of Emphasis: Biomechanics.

2001 Ph.D. Michigan State University Kinesiology. Area of Emphasis: Biomechanics and Mechanical Engineering. This author has no relevant disclosures.Susan Harkema, PhDUniversity of Louisville This author has no relevant disclosures.

14Swimming and Cardiovascular Fitness after SCI: A Pilot ProjectWednesday, May 02, 2018 09:30 AM - 10:30 AMLearning Objectives:Recognize the barriers to exercise after spinal cord injury and consider swimming as a form of exercise to suggest to patients after spinal cord injury.

Participants:Kessler A, Dayanidhi SShirley Ryan Abilitylab , Chicago , IL, USAAllison Kessler, MSc, MDShirley Ryan Abilitylab Bio:Allison Kessler, MSc, MD, is an Attending Physician at the Shirley Ryan Abilitylab (formerly

the Rehabilitation Institute of Chicago) and an Assistant Professor of Physical Medicine and Rehabilitation at Northwestern University’s Feinberg School of Medicine in Chicago, IL. She received her Bachelor’s degree in human evolutionary biology at Harvard in 2007. She then obtained her masters of science in bioscience, biomedicine and society, an integrated program including public health, sociology, biology, and ethical considerations at the London School of Economics. She then went on to earn her Medical degree from Northwestern University’s Feinberg School of Medicine. She completed her internship at Northwestern Memorial Hospital and Physical Medicine and Rehabilitation Residency followed by her fellowship in Spinal Cord Injury Medicine at the Rehabilitation Institute of Chicago (now the Shirley Ryan Abilitylab). She currently serves on the Rehabilitation Standards Committee of the American Spinal Injury Association. Her current research projects focus on swimming and cardiovascular fitness after spinal cord injury. Education:2016 – 2017: Spinal Cord Injury Medicine Fellowship. Shirley Ryan Abilitylab (formerly RIC)/McGaw Medical Center of Northwestern University, Chicago, IL.

2012 - 2016: Physical Medicine and Rehabilitation Residency. Rehabilitation Institute of Chicago (RIC)/McGaw Medical Center of Northwestern University, Chicago, IL.

2008 – 2012: MD Northwestern University, Feinberg School of Medicine (FSOM), Chicago, IL.

2007 – 2008: Masters of Science, Biomedicine Bioscience and Society. London School of Economics, London, England UK.

2003 - 2007: Bachelor of Arts, Human Evolutionary Biology. Harvard College, Cambridge, MA. This author has the following disclosures:

Research SupportResearch support from the Craig H Neilsen FoundationSudarshan Dayanidhi, MD, PhDShirley Ryan Abilitylab This author has the following disclosures:

Research SupportResearch support from the Craig H Neilsen Foundation

15Case reportWednesday, May 02, 2018 09:30 AM - 10:30 AMLearning Objectives:Understand the limitations of the latest proposed classification systems of thoracolumbar fractures and the indications for advanced imaging in the acute setting

Participants:1Clifton W, 2Tavanaiepour D, 2Rahmathulla G1Mayo Clinic Florida , Jacksonville , FL, USA; 2Uf Health Jacksonville , Jacksonville , FL, USAWilliam Clifton, MDMayo Clinic Florida Bio:Dr. Clifton completed his medical school training at the University of South Florida in Tampa, FL and is currently in his residency training in Neurologic Surgery at Mayo Clinic in Jacksonville, FLEducation:BS: University of Central Florida, 2007-2010

MD: University of South Florida COM, 2010-2014

Resident in Neurological Surgery: Mayo Clinic Florida, 2014-present

This author has no relevant disclosures.Daryoush Tavanaiepour, MDUf Health Jacksonville This author has no relevant disclosures.Gazanfar Rahmathulla, MDUf Health Jacksonville This author has no relevant disclosures.

16Inspiratory Muscle Training in Individuals with Spinal Cord Injuries Wednesday, May 02, 2018 09:30 AM - 10:30 AMLearning Objectives:Explain the use of inspiratory muscle training in individuals with chronic spinal cord injury participating in a community exercise program and the potential functional benefits.

Participants:1Sliwinski M, 2Boak S, 2Courville A, 2Dearwater M, 2Radhakrishnan S, 3Leathem J1Columbia University Medical Center , New York , NY, USA; 2Columbia University , New York , NY, USA; 3John F. Kennedy Medical Center , Edison , NJ, USAMartha Sliwinski, PT, PhD, MAColumbia University Medical Center Bio:My research focus is centered to individuals who have suffered a spinal cord injury. These individuals are in an advanced aging process in comparison to the normal population as well hospital readmission and challenges with quality of life. I am interested in pursuing interventions, particularly that have promise to prevent wellness decline in this population and to improve their quality of life. Collaborating with other researchers who have an interest in these

same principles provides promise for this population. My collaboration with community partners and centers serving this population has been an ongoing part of my research. My role as a practitioner for 38 years and an educator for 24 years in the field of physical therapy provides me with the knowledge and experience to support research initiatives with this population. Serving as an editor and chapter author for the text book Spinal Cord Injuries: Management and Rehabilitation provided me with the additional tools to have a broad knowledge for the comprehensive care and life challenges for individuals with a spinal cord injury. Education:Montgomery County Community College (Blue Bell, PA) AA 1975- 1977 General Studies Temple University (Philadelphia, PA) BS 1977-1979 Physical Therapy New York University (New York, NY) MA 1982-1985 Pathokinesiology New York University (New York, NY) PhD 1993-2002 PathokinesiologyThis author has no relevant disclosures.Sarah Boak, Student Physical TherapistColumbia University This author has no relevant disclosures.Aubrey Courville, Student Physical TherapistColumbia University This author has no relevant disclosures.Michelle Dearwater, Student Physical TherapistColumbia University This author has no relevant disclosures.Sneha Radhakrishnan, Student Physical TherapistColumbia University This author has no relevant disclosures.Jessica Leathem, DPTJohn F. Kennedy Medical Center This author has no relevant disclosures.

17Characterization of Volitional Electromyographic Signals in the Lower Extremity after Motor Complete Spinal Cord InjuryWednesday, May 02, 2018 09:30 AM - 10:30 AMLearning Objectives:Learning Objective: To learn about the presence of small volitional electromyographic signals below the level of injury even in subjects diagnosed as motor complete and to discuss the implications and applications of these signals.

Participants:1Heald E, 2Hart R, 1Kilgore K, 1Peckham P1Case Western Reserve Univsity , Cleveland , OH, United states; 2Louis Stokes Veterans Affairs Medical Center , Cleveland , OH, United states

Elizabeth Heald, Case Western Reserve Univsity Bio:Elizabeth Heald (formerly Thrailkill) is a PhD candidate in Biomedical Engineering at Case Western Reserve University (CWRU) in Cleveland Ohio. She received her bachelor’s degree in Biological Systems Engineering from the University of Nebraska-Lincoln in 2011. Ms. Heald is studying under the mentorship of Dr. Hunter Peckham and Dr. Kevin Kilgore. She is a graduate research assistant within the Cleveland FES Center, working at both MetroHealth Medical Center and at the Louis Stokes Cleveland VA Medical Center, where the goal of her research is to improve the control of implanted neuroprosthetic devices used to restore function to patients with paralysis caused by spinal cord injury. At CWRU, she is positioned in an environment where the expertise and collaboration necessary to perform this research is possible, working as part of an interdisciplinary team of doctors, therapists, engineers, technicians, and patients who all have one overarching goal: the clinical deployment of restorative technologies that will impact and improve the lives of people with spinal cord injuries. Education:Case Western Reserve University (Cleveland, OH), 2012-Present, PhD Candidate, Biomedical Engineering

University of Nebraska-Lincoln (Lincoln, NE), 2007-2011, BS, Biological Systems Engineering This author has no relevant disclosures.Ronald Hart, MSLouis Stokes Veterans Affairs Medical Center This author has no relevant disclosures.Kevin Kilgore, PhDCase Western Reserve Univsity This author has no relevant disclosures.P. Hunter Peckham, PhDCase Western Reserve Univsity This author has no relevant disclosures.

18Understanding and Preventing Loss to Follow-up: Experiences from the Spinal Cord Injury Model SystemsWednesday, May 02, 2018 09:30 AM - 10:30 AMLearning Objectives:To identify demographic and clinical factors associated with loss to follow-up at post-injury years 1-35 among 25,871 people with spinal cord injury enrolled in the National Spinal Cord Injury Database.

Participants:1Kim H, 2Cutter G, 3George B, 2Chen Y

1Duke Clinical Research Institute , Durham , NC, USA; 2University of Alabama at Birmingham , Birmingham , AL, United states; 3Thomas Jefferson University , Philadelphia , PA, United statesHwasoon Kim, PhDDuke Clinical Research Institute This author has no relevant disclosures.Gary Cutter, PhDUniversity of Alabama at Birmingham This author has no relevant disclosures.Brandon George, PhDThomas Jefferson University This author has no relevant disclosures.Yuying Chen, MD, PhDUniversity of Alabama at Birmingham Bio:Dr. Yuying Chen is a Professor with tenure in the Department of Physical Medicine and Rehabilitation, University of Alabama at Birmingham (UAB) in Birmingham, Alabama, USA. She also serves as the Director of the National Spinal Cord Injury Statistical Center (NSCISC), continuously funded by the National Institute on Disability, Independent Living, and Rehabilitation Research (NIDILRR) since 1984. Dr. Chen was trained in Taiwan as a physiatrist and earned a Master of Public Health from Yale University in 1996 and PhD in epidemiology from UAB in 2000. With the unique blend of clinical and research training, Dr. Chen has been very productive since she joined UAB in 1997 and gained national and international recognition for her research involving epidemiology, mortality, and secondary conditions after spinal cord injury (SCI) including urologic complications, pressure ulcers, and, more recently, obesity and cardiovascular health. Her research has been continuously funded through the NIDILRR, NIH, Paralyzed Veterans of America Research Foundation, and industries over the last 2 decades. She is a member of the Editorial Board of the Topics in Spinal Cord Injury Rehabilitation, Oversight Committee of the NINDS SCI Common Data Elements, and International SCI Data Set. She currently chairs the American Congress of Rehabilitation Medicine SCI Interdisciplinary Special Interest Group. As the NSCISC Director, Dr. Chen has provided consultation and technical assistance to investigators in the US and outside US who are interested in analyzing the SCI Model System National Database for research. In addition, Dr. Chen has also served as a mentor/preceptor in various capacities for students, resident physicians, and visiting scholars at UAB. Education:2000 Ph.D. University of Alabama at Birmingham (UAB), Birmingham, AL 1996 M.P.H. Yale University, New Haven, CT 1990 M.D. Chung Shan Medical University, Taichung, Taiwan This author has no relevant disclosures.

19Missing data in spinal cord injury survey research: racial differences Wednesday, May 02, 2018 09:30 AM - 10:30 AMLearning Objectives:

Describe racial/ethnic differences in responding to survey questions and discuss the strategies aimed to improve missing data in a longitudinal study of people with spinal cord injury.

Participants:1Chen Y, 2Lin H, 2Tseng T, 1Wen H, 1DeVivo M1University of Alabama at Birmingham , Birmingham , Alabama, USA; 2Louisiana State University Health Sciences Center , New Orleans , Louisiana, USAYuying Chen, MD, PhDUniversity of Alabama at Birmingham Bio:Dr. Yuying Chen is a Professor with tenure in the Department of Physical Medicine and Rehabilitation, University of Alabama at Birmingham (UAB) in Birmingham, Alabama, USA. She also serves as the Director of the National Spinal Cord Injury Statistical Center (NSCISC), continuously funded by the National Institute on Disability, Independent Living, and Rehabilitation Research (NIDILRR) since 1984. Dr. Chen was trained in Taiwan as a physiatrist and earned a Master of Public Health from Yale University in 1996 and PhD in epidemiology from UAB in 2000. With the unique blend of clinical and research training, Dr. Chen has been very productive since she joined UAB in 1997 and gained national and international recognition for her research involving epidemiology, mortality, and secondary conditions after spinal cord injury (SCI) including urologic complications, pressure ulcers, and, more recently, obesity and cardiovascular health. Her research has been continuously funded through the NIDILRR, NIH, Paralyzed Veterans of America Research Foundation, and industries over the last 2 decades. She is a member of the Editorial Board of the Topics in Spinal Cord Injury Rehabilitation, Oversight Committee of the NINDS SCI Common Data Elements, and International SCI Data Set. She currently chairs the American Congress of Rehabilitation Medicine SCI Interdisciplinary Special Interest Group. As the NSCISC Director, Dr. Chen has provided consultation and technical assistance to investigators in the US and outside US who are interested in analyzing the SCI Model System National Database for research. In addition, Dr. Chen has also served as a mentor/preceptor in various capacities for students, resident physicians, and visiting scholars at UAB. Education:Year Degree Institution 2000 Ph.D. University of Alabama at Birmingham (UAB), Birmingham, AL 1996 M.P.H. Yale University, New Haven, CT 1990 M.D. Chung Shan Medical University, Taichung, Taiwan This author has no relevant disclosures.Hui-Yi Lin, PhDLouisiana State University Health Sciences Center This author has no relevant disclosures.Tung-Sung Tseng, DrPHLouisiana State University Health Sciences Center This author has no relevant disclosures.Huacong Wen, MD, MSUniversity of Alabama at Birmingham This author has no relevant disclosures.

Michael DeVivo, DrPHUniversity of Alabama at Birmingham This author has no relevant disclosures.

20Responsiveness and Minimal Clinically Important Difference of the Capabilities of Upper Extremity TestWednesday, May 02, 2018 09:30 AM - 10:30 AMLearning Objectives:Discuss the responsiveness of the CUE-T and the MCID based on subjective and objective anchors.

Participants:1Marino R, 1Sinko R, 1Leiby B, 2Bryden A, 3Nemunaitis G, 4Chen D, 5Backus D1Thomas Jefferson University , Philadelphia , PA, USA; 2Case Western Reserve University , Cleveland , OH, USA; 3Metrohealth Medical Center , Cleveland , OH, USA; 4Shirley Ryan Abilitylab , Chicago , IL, USA; 5Shepherd Center , Atlanta , GA, USARalph Marino, MD, MSThomas Jefferson University Bio:Dr. Ralph Marino is Professor of Rehabilitation Medicine at Thomas Jefferson University. He is board certified in Physical Medicine and Rehabilitation and in the subspecialty of Spinal Cord Injury Medicine. He completed residency training in PM&R at Jefferson in 1987, and has been on the faculty from 1987- 1998, and from 2002 to present. Dr. Marino is the Project Director of the Regional Spinal Cord Injury Center of the Delaware Valley, which is funded as a Spinal Cord Injury Model System of Care by the Administration for Community Living, HHS. He has over 60 peer-reviewed publications and over 70 abstracts. Education:Eckerd College (St. Petersburg, FL), BS 1974-78 Biopsychology

Jefferson Medical College (Philadelphia, PA), MD 1978-82 Medicine

Roanoke Memorial Hospital (Roanoke, VA), 1982-1983, Internship

Thomas Jefferson University Hospital (Philadelphia, PA), 1984-1987 PM&R

University of Pennsylvania (Philadelphia, PA), MS 1993-98 Clinical Epidemiology

This author has the following disclosures: Consultant

Vertex Pharmaceuticals, Consultant for clinical trials in SCI.Rebecca Sinko, OTD, OTR/LThomas Jefferson University This author has no relevant disclosures.

Benjamin Leiby, PhDThomas Jefferson University This author has no relevant disclosures.Anne Bryden, OTR/LCase Western Reserve University This author has no relevant disclosures.Greg Nemunaitis, MDMetrohealth Medical Center This author has no relevant disclosures.David Chen, MDShirley Ryan Abilitylab This author has no relevant disclosures.Deborah Backus, PT, PhDShepherd Center This author has no relevant disclosures.

21ReInventing yourself after SCI: A bridge from rehabilitation to real worldWednesday, May 02, 2018 09:30 AM - 10:30 AMLearning Objectives:Attendees will be able to describe an intervention to target self-efficacy for people with SCI who have been recently discharged from rehabilitation, as well as the short and long term effects of the intervention.

Participants:Coker JCraig Hospital , Englewood , CO, United statesJennifer Coker, MPHCraig Hospital Bio:Ms. Coker has worked in the field of traumatic spinal cord injury (SCI) since 1997. She obtained a Master of Public Health from the Rollins School of Public Health at Emory University in May 2001, where she won the James W Alley Award for Outstanding Service to Disadvantaged Populations, and is currently a PhD student in the Clinical Sciences program at the University of Colorado-Anschutz Medical Campus. She has presented research at national conferences of ASIA, the American Association of Spinal Cord Injury Psychologists and Social Workers (now ASCIP), the American Public Health Association, and the American Psychological Association. In addition, Ms. Coker has won several awards for research presentations and publications. She has been a Research Associate at Craig Hospital since April 2012 and works primarily with the SCI Model Systems (SCIMS) projects. Ms. Coker is the PI for the Craig H Neilsen Foundation funded project, A Bridge from Rehabilitation to Real-World: Reinventing Yourself after SCI, the SCIMS module, Utilization of Complementary and Integrative Healthcare to Treat Pain in

People with SCI, and Co-PI for a NIDILRR-funded project, A Multi-site Randomized Controlled Trial of an Intervention to Improve Outcomes after Spinal Cord Injury.Education:Berry College (Mt Berry, GA), BA 1997, Psychology & Child Development

Rollins School of Public Health, Emory University (Atlanta, GA), MPH 2001, Behavioral Health & Education

Clinical Science Graduate Program, University of Colorado-Anschutz Medical Campus (Aurora, CO), PhD in progress, Clinical InvestigationsThis author has the following disclosures:

Research Support Other (see below)

Research Support: Craig H Neilsen Neilsen Foundation (#288944)

Other-Employment: Craig Hospital, Englewood, CO; Medical University of South Carolina, Charleston, SC

Other-Volunteer: Cycle of Hope Board of Directors (member)

22The Effects of an Exercise Program to Accompany Biologic or Therapeutic Clinical Trials in People with Chronic Spinal Cord InjuryWednesday, May 02, 2018 09:30 AM - 10:30 AMLearning Objectives:Describe the effects of a 12-week training program on multiple body systems in people with chronic SCI.

Participants:1Gant K, 2Kathleen N, 1Cowan R, 3Field-Fote E, 4Nash M, 5Kressler J, 1Thomas C, 1Castellanos M, 6Widerstrom-Noga E1Department of Neurological Surgery, Miami Project to Cure Paralysis, University of Miami Leonard M. Miller School of Medicine , Miami , FL, USA; 2Covance Central Laboratory Services , Indianapolis , IN, USA; 3Emory University School of Medicine, Division of Physical Therapy; Professor, Georgia Institute of Technology, School of Biological Sciences; Director, Spinal Cord Injury Research & the Hulse Spinal Cord Injury Laboratory, Shepherd Center , Atlanta , GA, USA; 4Department of Neurological Surgery, Department of Physical Medicine and Rehabilitation Medicine, Miami Project to Cure Paralysis, University of Miami Leonard M. Miller School of Medicine , Miami , FL, USA; 5Department of Exercise and Nutritional Sciences, College of Health and Human Services, San Diego State University , San Diego , CA, USA; 6Department of Neurological Surgery, Miami Project to Cure Paralysis, University of Miami Leonard M. Miller School of Medicine, 1095 Nw 14Th Terrace, Miami, Fl 33136; Bruce W. Carter Department of Veterans Affairs Medical Center , Miami , FL, USA

Katie Gant, PhDDepartment of Neurological Surgery, Miami Project to Cure Paralysis, University of Miami Leonard M. Miller School of Medicine Bio:Katie Gant, PhD is an Assistant Scientist at The Miami Project to Cure Paralysis and Department of Neurological Surgery at The University of Miami. She is a part of The Miami Project’s clinical trials program, where she is responsible for the recruitment and screening of research participants, as well as the collection and analysis of research data. She also contributes to The Miami Project’s educational program and outreach efforts. She completed her BS and MS degrees in biomedical engineering at Tulane University and her PhD in biomedical engineering at The University of Miami. Education:Tulane University (New Orleans, LA), BS 2001-2005 Biomedical Engineering

Tulane University (New Orleans, LA), MS 2005-2007 Biomedical Engineering

The University of Miami (Miami, FL), PhD 2010-2016This author has no relevant disclosures.Nagle Kathleen, BSCovance Central Laboratory Services This author has no relevant disclosures.Rachel Cowan, PhDDepartment of Neurological Surgery, Miami Project to Cure Paralysis, University of Miami Leonard M. Miller School of Medicine This author has no relevant disclosures.Edelle Field-Fote, PT, PhDEmory University School of Medicine, Division of Physical Therapy; Professor, Georgia Institute of Technology, School of Biological Sciences; Director, Spinal Cord Injury Research & the Hulse Spinal Cord Injury Laboratory, Shepherd Center This author has no relevant disclosures.Mark Nash, PhDDepartment of Neurological Surgery, Department of Physical Medicine and Rehabilitation Medicine, Miami Project to Cure Paralysis, University of Miami Leonard M. Miller School of Medicine This author has no relevant disclosures.Jochen Kressler, PhDDepartment of Exercise and Nutritional Sciences, College of Health and Human Services, San Diego State University This author has no relevant disclosures.Christine Thomas, PhDDepartment of Neurological Surgery, Miami Project to Cure Paralysis, University of Miami Leonard M. Miller School of Medicine This author has no relevant disclosures.

Mabelin Castellanos, BSDepartment of Neurological Surgery, Miami Project to Cure Paralysis, University of Miami Leonard M. Miller School of Medicine This author has no relevant disclosures.Eva Widerstrom-Noga, DDS, PhDDepartment of Neurological Surgery, Miami Project to Cure Paralysis, University of Miami Leonard M. Miller School of Medicine, 1095 Nw 14Th Terrace, Miami, Fl 33136; Bruce W. Carter Department of Veterans Affairs Medical Center This author has no relevant disclosures.

23The Accuracy of Wireless Accelerometers in Detecting the Leg Movements of Young Infants: A Pilot StudyWednesday, May 02, 2018 09:30 AM - 10:30 AMLearning Objectives:LEARNING OBJECTIVE: The results from the current study represent a first step in using wearable technology to monitor the frequency of infant LMs and kicks over developmental time. It is anticipated that this type of technology will enable parents of infants with disabilities, e.g. Down syndrome and spina bifida, to take advantage of telehealth and work with their child’s therapist on a frequent basis without requiring an in-clinic visit to monitor how often their child is moving their legs.

Participants:1Chapman D, 2Lopez C, 2Zhao K1St. Catherine University , Minneapolis , MN, United states; 2Mayo Clinic , Rochester , MN, 55905David Chapman, PT, PhDSt. Catherine University Bio:Dr. Chapman graduated from the Physical Therapy Program at Indiana University. He earned a Master of Science degree in Education from Southern Illinois University - Carbondale and a PhD from Indiana University in Kinesiology and Developmental Psychology. He has practiced as a physical therapist with inpatient and outpatient adult and pediatric patients as well as in the acute rehabilitation setting with a focus on the management of patients with congenital and acquired neuromuscular diagnoses like Down syndrome, Spina Bifida, stroke, traumatic brain injury, ALS, and Parkinson's disease. Dr. Chapman has published and presented nationally and internationally on topics related to the impact the context has on movement, the developmental profiles of infants with neuromuscular conditions, the sensory consequences of movement, and on the management of pediatric athletes. Prior to joining the faculty at St. Catherine University, Dr. Chapman served for many years as a faculty member in the physical therapy program at Indiana University. Most recently he was the Supervisor of Rehabilitation Services for Bloomington Hospital in Bloomington, Indiana. Dr. Chapman currently teaches content in the area of rehabilitation, pediatrics, neurologic physical therapy, and leadership/administration.

Education:Indiana University Indianapolis, IN 1995-2000 Physical Therapy Bachelor of Science, August, 2000

Indiana University Bloomington, IN 1992-1999 Human Performance-Special Populations/Developmental Psychology Doctor of Philosophy, August, 1999

Southern Illinois University – Carbondale Carbondale, IL 1981-1984 Physical Education/Adapted Physical Education Master of Science May, 1984

The University of Iowa Iowa City, Iowa 1977-1980 Exercise Science/Secondary Education May, 1980 This author has the following disclosures:

Other (see below)Dr. Chapman is employed by St. Catherine University as an Associate Professor and receives a salary. The work being presented is supported by the Mayo Clinic Children's Research Center. Cesar Lopez, MSMayo Clinic This author has the following disclosures:

Other (see below)Mr. Lopez is employed by Mayo Clinic Department of Physical Medicine and Rehabilitation as an engineer and receives a salary. The work being presented is supported by the Mayo Clinic Children's Research Center.Kristin Zhao, PhDMayo Clinic This author has the following disclosures:

Other (see below)Dr. Zhao is employed by Mayo Clinic Department of Physical Medicine and Rehabilitation as an Associate Consultant II and receives a salary. The work being presented is supported by the Mayo Clinic Children's Research Center.

24The effects of acute intermittent hypoxia on respiratory function in humans with spinal cord injury: a pilot study.Wednesday, May 02, 2018 09:30 AM - 10:30 AMLearning Objectives:To discuss the effects of a single session of acute intermittent hypoxia on respiratory function after spinal cord injury, and consider how the effects may vary between individuals.

Participants:1Sutor T, 2Doughty K, 3Ahmed S, 3Fuller D, 3Mitchell G, 4Fox E1University of Florida , Gainesville , Florida, United states; 2Brooks Rehabilitation , Jacksonville , Florida, United states; 3University of Florda , Gainesville , Florida, United states; 4University of Florida, Brooks Rehabilitation , Gainesville , Florida, United statesTommy Sutor, MS, CSCSUniversity of Florida Bio:Tommy Sutor, MS, CSCS, is a pre-doctoral student in Rehabilitation Science at the University of Florida. He completed undergraduate and master's degrees in exercise science from East Stroudsburg University in Pennsylvania, during which time he also became a Certified Strength and Conditioning Specialist through the National Strength and Conditioning Association, a certification which he maintains to this day. Following completion of the master's degree, he went on to become an exercise trainer and Program Director at a community gym for people with spinal cord injuries and other neurological disorders that result in paralysis. His four years of experience guiding clients with spinal cord injuries through activity-based exercise programs sparked his curiosity about the physiology of different modalities of activity-based exercise, and why activity-based exercise works better for some people with spinal cord injuries than others. He is currently in his third year of the Rehabilitation Science PhD program at the University of Florida.Education:• PhD Student, Rehabilitation Science August 2015 – Present University of Florida, Gainesville, Florida My focus in my PhD studies under Dr. Emily Fox is to investigate novel ways to enhance outcomes of physical rehabilitation for people with spinal cord injuries, specifically with the most severe, motor complete injuries. As a career goal I hope to conduct research into ways to both enhance physical rehabilitation outcomes as well as explore ways that physical rehabilitation can be used in conjunction with regenerative or restorative therapies designed to heal an injured spinal cord, and ultimately work towards finding a cure for paralysis. • M.S. Exercise Science August 2011 East Stroudsburg University, East Stroudsburg, Pennsylvania (CAAHEP accredited) Thesis Title: “Does a Standard Post-Activation Potentiation Scheme Potentiate Performance in the Throws?” • B.S. Exercise Science May 2009 East Stroudsburg University, East Stroudsburg, Pennsylvania (CAAHEP accredited) This author has no relevant disclosures.

Kathryn Doughty, PT, DPT, NCSBrooks Rehabilitation This author has no relevant disclosures.Shakeel Ahmed, PTUniversity of Florda This author has no relevant disclosures.David Fuller, PhDUniversity of Florda This author has no relevant disclosures.Gordon Mitchell, PhDUniversity of Florda This author has no relevant disclosures.Emily Fox, PT, DPT, PhD, NCSUniversity of Florida, Brooks Rehabilitation This author has no relevant disclosures.

25Appraisals of Disability in Middle Adulthood Following Pediatric-Onset Spinal Cord InjuryWednesday, May 02, 2018 09:30 AM - 10:30 AMLearning Objectives:To describe cognitive appraisals in individuals with pediatric-onset spinal cord injury (SCI) during middle adulthood.

Participants:1Chlan K, 2Zebracki K, 3Kennedy P, 2Vogel L1Shriners Hospitals Fo Children , Chicago , IL, United states; 2Shriners Hospitals for Children , Chicago , IL, United states; 3Deceased; The National Spinal Injuries Centre, Stoke Mandeville Hospital , Buckinghamshire , , UKKathleen Chlan, BAShriners Hospitals Fo Children Bio:Conducting research with individuals with pediatric-onset spinal cord injuries has been the focus of my research career. Since 2002, I have served as Operations Coordinator on the study entitled, Long-term Outcomes and Life Satisfaction of Adults with Pediatric-Onset Spinal Cord Injuries at Shriners Hospitals for Children-Chicago. My responsibilities include managing patient recruitment, conducting initial and follow-up interviews, maintaining enrollment/ implementing techniques to minimize attrition, training of research assistants, data analyses, IRB management, and preparing abstracts and manuscripts for presentation and publication. Furthermore, from 2002-2008, I served as a Research Specialist on a grant entitled, “Providing young adolescents with disabilities, work experience and guidance toward adulthood: A Summer Transition Program. I was responsible for orienting and assisting the study coordinator, assisting with subject recruitment, and organizing reunions of former patients. From 2006-2007, I additionally

served as Research Specialist on a study entitled, International Standards for Neurological Classification of Spinal Cord Injury: Reliability testing when applied to children and youth. I was responsible for subject recruitment as well as conducting repeated measures of the standardized and pediatric modified ISCSCI motor and sensory exam. Moreover, from 2015-2017 I served as Research Specialist on as study entitled, Living with SCI: Middle adulthood psychosocial outcomes of pediatric-SCI. As lead or co-author, I have published 20 manuscripts on long-term outcomes among individuals with pediatric-onset spinal cord injury as well as 75 abstracts and presentations presented at both national and international scientific meetings. I have been a member of American Spinal Injury Association (ASIA) since 2011 and serve on its Pediatric Committee.

Education:

Saint Mary’s University Winona MN BA 05/02 Biology, pre-med This author has no relevant disclosures.Kathy Zebracki, PhDShriners Hospitals for Children This author has no relevant disclosures.Paul Kennedy, Deceased; The National Spinal Injuries Centre, Stoke Mandeville Hospital This author has no relevant disclosures.Lawrence Vogel, MDShriners Hospitals for Children This author has no relevant disclosures.

26Malnutrition after spinal cord injuries: a systematic reviewWednesday, May 02, 2018 09:30 AM - 10:30 AM

Participants:1Wong S, 1Kenssous N, 1Lewis S, 2Jamous A, 1Saif M1National Spinal Injuries Centre, Stoke Mandeville Hospital , Aylesbury , , UK; 2Royal Buckinghamshire Hospital , Aylesbury , , UKSamford Wong, MSc (Med Sci)., PhD., RDNational Spinal Injuries Centre, Stoke Mandeville Hospital Bio:Samford Wong is NSIC Dietetic Lead in Research / Lead Dietitian, National Spinal Injuries Centre, Stoke Mandeville Hospital Department of Nutrition and Dietetics, Stoke Mandeville Hospital, Buckinghamshire Healthcare NHS Trust, Aylesbury HP21 8AL; Tel: 01296 315775 Education:Education: 2004: BSc (Hons)., RD; 2006: MSc (Med Sci);

2010; Dip Adv Diet: 2011; 2012: MPhil / PhD PTLLS: 2013; CMS: 2014 This author has the following disclosures:

Research SupportResearch grant from Yakult HonshaNoureddine Kenssous, BSc (Hons)National Spinal Injuries Centre, Stoke Mandeville Hospital This author has no relevant disclosures.Sarah Lewis, MScNational Spinal Injuries Centre, Stoke Mandeville Hospital This author has no relevant disclosures.Ali Jamous, MDRoyal Buckinghamshire Hospital This author has no relevant disclosures.Mofid Saif, MD., FRCS., FRCPNational Spinal Injuries Centre, Stoke Mandeville Hospital This author has no relevant disclosures.

27Cerebrovascular reactivity and cognitive function are impaired following chronic high-thoracic spinal cord injuryWednesday, May 02, 2018 09:30 AM - 10:30 AMLearning Objectives:To use an animal model to investigate long-term cerebrovascular consequences following chronic high-thoracic SCI.

Participants:1Chornenka K, 1Jia M, 2Phillips A, 3Wang S, 1Yung A, 1Zheng M, 4Leong S, 1Kozlowski P, 3Fan F, 3Roman R, 1Krassioukov A1International Collaboration on Repair Discoveries (Icord), Faculty of Medicine, University of British Columbia , Vancouver , BC, Canada; 2Physiology and Pharmacology, Cumming School of Medicine, Libin Cardiovascular Institute, Hotchkiss Brain Institute, University of Calgary , Calgary , AB, Canada; 3Department of Pharmacology & Toxicology, the University of Mississippi Medical Center , Jackson , MS, USA; 4University of British Columbia , Vancouver , BC, CanadaKarina Chornenka, International Collaboration on Repair Discoveries (Icord), Faculty of Medicine, University of British Columbia Bio:Karina Chornenka is a second year medical student at the University of British Columbia Faculty of Medicine. Prior to beginning her medical training in 2016, she studied biology and philosophy

at York University in Toronto, Ontario. She was involved in a research studentship at the Hospital for Sick Children in Toronto, Ontario during her undergraduate studies where she helped create an in vitro model to test p53 functional restoration following CRISPR/Cas9 repair of heterozygous TP53 mutations in Li-Fraumeni Syndrome patient-derived fibroblasts. In 2017, she received the UBC Faculty of Medicine Summer Student Research Award to study autonomic dysfunction and cerebrovascular consequences of spinal cord injury supervised by Dr. Krassioukov at the International Collaboration On Repair Discoveries. Education:2016-2020 Doctor of Medicine Candidate, University of British Columbia MD Undergraduate Program, Vancouver, BC.

2012-2016 Bachelor of Science, Honours Double Major Biology & Philosophy, York University, Toronto ONThis author has no relevant disclosures.Mengyao Jia, B.Sc.International Collaboration on Repair Discoveries (Icord), Faculty of Medicine, University of British Columbia This author has no relevant disclosures.Aaron Phillips, PhDPhysiology and Pharmacology, Cumming School of Medicine, Libin Cardiovascular Institute, Hotchkiss Brain Institute, University of Calgary This author has no relevant disclosures.Shaoxun Wang, M.Sc.Department of Pharmacology & Toxicology, the University of Mississippi Medical Center This author has no relevant disclosures.Andrew Yung, M.Sc.International Collaboration on Repair Discoveries (Icord), Faculty of Medicine, University of British Columbia This author has no relevant disclosures.Mei Mu Zi Zheng, M.Sc.International Collaboration on Repair Discoveries (Icord), Faculty of Medicine, University of British Columbia This author has no relevant disclosures.Sarah Leong, B.Kin.University of British Columbia This author has no relevant disclosures.Piotr Kozlowski, M.Sc., Ph.D.International Collaboration on Repair Discoveries (Icord), Faculty of Medicine, University of British Columbia This author has no relevant disclosures.

Fan Fan, MD, MSDepartment of Pharmacology & Toxicology, the University of Mississippi Medical Center This author has no relevant disclosures.Richard Roman, PhDDepartment of Pharmacology & Toxicology, the University of Mississippi Medical Center This author has no relevant disclosures.Andrei Krassioukov, MD, PhD, FRCPCInternational Collaboration on Repair Discoveries (Icord), Faculty of Medicine, University of British Columbia This author has the following disclosures:

Research Support Other (see below)

ONGOING RESEARCH SUPPORT 1. Craig H. Neilsen Foundation QOL Project Grants. Title: Motherhood after spinal cord injury: lactation, breastfeeding, and autonomic dysreflexia. Period: 2016-2017 ROLE: PI

2. Heart and Stroke GIA 2016/17. Title: When are blood vessels “ready to rupture”? Cerebrovascular health following spinal cord injury: from animal models to clinical practice. Period: 2016 – 2019 ROLE: PI

3. Pfizer Canada Inc. Title: A Phase II, Open-Label Exploratory Study Investigating the Efficacy of Toviaz for Treatment of Adult Patients with Spinal Cord Injury (SCI) with Neurogenic Detrusor Overactivity (NDO) for Amelioration of Autonomic Dysreflexia (AD). Period: Nov 2015 –Feb 2017 ROLE: PI

4. Rick Hansen Institute. Title: Development of a mobile app (telephone/iPod application) for emergency department physicians on recognition and management of life-threatening episodes of autonomic dysreflexia: “ABC of AD for the EM doc”. Period: Apr 2015-Dec 2016. ROLE: PI

5. Vancouver Foundation. Title: Vancouver Foundation Start-up Funds: Period: April 2015 – March 2017 ROLE: PI

6. Christopher and Dana Reeve Foundation. Title: Big Idea Cardiovascular Committee. Period: Feb 2015-Aug2015. ROLE: PI

7. Rick Hansen Institute/ RHI Pilot Studies - Optimizing Neurorecovery Following SCI. Title: Effect of epidural stimulation on cardiovascular control following spinal cord injury. Period: Mar 2015-Mar 2017.

ROLE: PI

8. Rick Hansen Foundation/International Collaboration On Repair Discoveries (ICORD)/Seed Grants. Title: Development of evidence-based guidelines for blood pressure management during iatrogenically-induced autonomic dysreflexia in those with spinal cord injury: the limits of cerebral autoregulation. Period: Apr 2014-Jun 2016. PI: Dr. Stacy Elliott. ROLE: Co-Investigator

9. Department of Defense USA. Title: Alleviating autonomic dysreflexia after spinal cord injury. Period: September 2014-August 2017. ROLE: PI

10. Craig H. Neilsen Foundation/ Neilsen Senior Research Grant. Title: Cardiac function after spinal cord injury: from bench to bedside. Period: July 2013-June 2017. ROLE: PI 11. Rick Hansen Institute. Title: Validation of the International Autonomic Standards for evaluation of individuals with chronic spinal cord injury. Period: March 2013- March 2017. ROLE: PI

12. Rick Hansen Foundation. Title: Improving Cardiovascular Health for Canadians Living with SCI: Effects of Exercise, sex Differences, and Targeted Clinical Education. Period: April 2012-March 2017. ROLE: PI

13. Rick Hansen Institute / Operating Grant. Title: BOTOX treatment for neurogenic detrusor hyperreflexia and prevention of autonomic dysreflexia following spinal cord injury. Period: July 2012 – Jan. 2017. ROLE: PI

14. Canadian Institutes of Health Research (CIHR) / Chronic disease risk and intervention strategies team grant. Title: Improving cardiovascular health for Canadians living with spinal cord injury: effects of exercise and targeted education. Period: Dec. 2011-Nov. 2016. ROLE: PI

15. Craig H. Neilsen Foundation/Christopher and Dana Reeve Foundation. Title: Recovery of cardiovascular function with epidural stimulation after human spinal cord injury. Period: January 2015-December 2017. PI: Dr. Susan Harkema ROLE: Co-Investigator

16. Canadian Institutes of Health Research (CIHR) / Operating grant. Title: Beyond VO2peak: Understanding exercise-induced changes in cardiovascular function after

stroke. Period: 2011-2015. PI: Dr. J. Eng ROLE: Co-Investigator

17. International Spinal Research Trust / Operating grant. Title: Peripheral Sympathetic and sensory plasticity in bladder and bowel circuitry in chronic spinal cord injury. Period: Jan. 2011-Aug. 2014. PI: Dr. M. Ramer ROLE: Co-Investigator

18. Rick Hansen Institute Start Up Funds. Title: Rick Hansen Institute Start-Up Funds. Period: March 2007 – March 2020. ROLE: PI

OTHER

Coloplast and WellSpect

28Non-invasive cervical electrical stimulation for SCI Wednesday, May 02, 2018 09:30 AM - 10:30 AMLearning Objectives:Learning objective 1: Describe how cervical electrical stimulation may be used to both measure and strengthen circuit function after spinal cord injury.

Participants:1Wu Y, 2Santiago T, 2Saeed S, 2LiMonta J, 2Yung L, 3Kastuar S, 2Hussain J, 2Guber K, 4Weir J, 5Carmel J, 1Harel N1James J. Peters Vamc, Icahn School of Medicine at Mount Sinai , Bronx , NY, USA; 2James J. Peters Vamc , Bronx , NY, USA; 3Icahn School of Medicine at Mount Sinai , New York , NY, USA; 4University of Kansas , Lawrence , KS, USA; 5Burke Medical Research Institute , White Plains , NY, USAYu-Kuang Wu, PT, PhDJames J. Peters Vamc, Icahn School of Medicine at Mount Sinai This author has no relevant disclosures.Tiffany Santiago, BSJames J. Peters Vamc This author has no relevant disclosures.Sana Saeed, BSJames J. Peters Vamc This author has no relevant disclosures.James LiMonta, BSJames J. Peters Vamc

This author has no relevant disclosures.Lok Yung, MDJames J. Peters Vamc This author has no relevant disclosures.Shivani Kastuar, BSIcahn School of Medicine at Mount Sinai This author has the following disclosures:Jasmeen Hussain, BSJames J. Peters Vamc This author has the following disclosures:Kenneth Guber, BAJames J. Peters Vamc This author has the following disclosures:Joseph Weir, PhDUniversity of Kansas This author has the following disclosures:Jason Carmel, MD, PhDBurke Medical Research Institute This author has no relevant disclosures.Noam Harel, MD, PhDJames J. Peters Vamc, Icahn School of Medicine at Mount Sinai Bio:Noam Y. Harel, MD, PhD, is an Investigator at the Spinal Cord Damage Research Center, Staff Physician at the James J. Peters VA Medical Center, and Associate Professor in the Departments of Neurology and Rehabilitation Medicine at Icahn School of Medicine at Mount Sinai, all in New York City. He obtained his bachelor’s degree in biology from the University of Pennsylvania in 1992, then stayed at Penn to obtain his Medical and Doctoral (Molecular Biology) degrees in 2000. He completed residency in Neurology at New York-Presbyterian Hospital-Columbia Campus, followed by a neuroscience fellowship at Yale University before joining Yale’s faculty as a neurologist and basic neuroscientist. Dr. Harel is board-certified in Adult Neurology, and has subspecialty certification in Neural Repair and Rehabilitation.

He has authored over 25 publications in international peer-reviewed journals, as well as given invited presentations at regional, national, and international meetings. He served as senior author on two chapters for the 13th edition of Merritt’s Neurology, one of the pre-eminent textbooks of clinical neurology. He has been funded by NINDS, VA, New York State, ALS Association, and Neilsen Foundation. Dr. Harel practices clinical neurology and spinal cord medicine in addition to running a clinical research program in SCI neurorehabilitation. He runs five human clinical research studies, with a main emphasis on non-invasive methods of electrical and magnetic nerve stimulation to strengthen spared neural circuits after SCI and ALS. He also performs research on targeted physical exercises, balance function, and spasticity.Education:University of Pennsylvania (Philadelphia, PA), BA 1988-1992 Biology

University of Pennsylvania (Philadelphia, PA), PhD, 1992-1998 Molecular Biology

University of Pennsylvania (Philadelphia, PA), MD, 1992-2000

Pennsylvania Hospital (Philadelphia, PA), Internal Medicine Internship 2000-2001

New York-Presbyterian Hospital (New York, NY), Adult Neurology Residency 2001-2004

Yale University School of Medicine (New Haven, CT), Neurobiology Fellowship 2004-2005This author has the following disclosures:

ConsultantAdare Pharmaceuticals, Advisory Board

29Intermittent catheterization: The devil is in the detailsWednesday, May 02, 2018 09:30 AM - 10:30 AMLearning Objectives:Cochrane is considered the gold standard for providing evidence using a systematic review and meta-analysis.

Here we present the results of an independent appraisal of the data and analyses presented in the 2014 Cochrane review, which will change your mind on the conclusions drawn by the authors.

Participants:1Christison K, 1Walter M, 2Wyndaele J, 3Kennelly M, 4Kesslerr T, 5Noonan V, 5Fallah N, 1Krassioukov A1International Collaboration on Repair Discoveries (Icord), Faculty of Medicine, University of British Columbia , Vancouver , BC, Canada; 2Department of Urology, University of Antwerp , Antwerp , , Belgium; 3Department of Urology, Carolinas Medical Center , Charlotte , NC, USA; 4Neuro-Urology, Spinal Cord Injury Center & Research, Balgrist University Hospital , Zürich , , Switzerland; 5Rick Hansen Institute , Vancouver , BC, CanadaKathleen Christison, RN, CNCC(C), BScNInternational Collaboration on Repair Discoveries (Icord), Faculty of Medicine, University of British Columbia Bio:Kathleen Christison, RN, CNCC(C), BScN, is a second-year medical student in the University of British Columbia’s (UBC) Northern Medical Program and a Certified Nurse in Critical Care (Canada). After receiving a Bachelor of Science in Nursing with a focus on critical care from the University of Northern British Columbia, Kathleen worked for five years in intensive care units and post-anaesthetic recovery rooms across British Columbia. She went on to become certified in Advanced Cardiac Life Support and Continuous Renal Replacement Therapy. Kathleen entered medical school at UBC in 2016 in the Northern Medical Program relocating to Prince George, BC. Today, Kathleen serves on the Years 1 and 2 Subcommittee and Program Evaluation, Planning and Improvement Subcommittee for the UBC Faculty of Medicine MD Undergraduate

Program, the Pre-Clinical Education Advisory Committee for the Northern Medical Program and acts as the Northern Medical Program Vice President Academic for the UBC Medicine 2020 Class Council. Kathleen was a 2017 award recipient of the UBC Faculty of Medicine Summer Student Research Program and as a result was awarded a grant to conduct research with the Autonomic Research Unit at the International Collaboration On Repair Discoveries in Vancouver, BC. She continues her work with this group through the UBC Faculty of Medicine Medical Undergraduate Program ‘FLEX’ curriculum. Education:University of Northern British Columbia (Prince George, BC), BScN 2007-2011 Registered Nursing

Canadian Nurses Association (CNA) (Vancouver, BC), CNCC(C) 2015 Certified Nursing in Critical Care Canada

University of British Columbia, Northern Medical Program (Prince George, BC) MD 2016 – Present Medical Student Year II This author has the following disclosures:

Research Support2017 Faculty of Medicine Summer Student Research Program and the Florence E. Heighway Summer Research Award Recipient Matthias Walter, MD, FEBUInternational Collaboration on Repair Discoveries (Icord), Faculty of Medicine, University of British Columbia This author has the following disclosures:

Research Support2017 Michael Smith Foundation for Health Related (MSFHR) Postdoctoral Research Trainee Award Recipient, co-funded by the Rick Hansen Institute (RHI); WellSpect Research Grant-in-Aid RecipientJean-Jacques Wyndaele, MD, PhD, FEBUDepartment of Urology, University of Antwerp This author has no relevant disclosures.Michael Kennelly, MD, FACSDepartment of Urology, Carolinas Medical Center This author has the following disclosures:

Research Support Consultant

Research Support - Allergan, Boston scientific, Coloplast, Contura, Cook Myosite, Dignify Therapeutics, Taris

Consultant - Allergan, Astellas, Boston Scientific, CogentixThomas Kesslerr, MD, FEBUNeuro-Urology, Spinal Cord Injury Center & Research, Balgrist University Hospital This author has no relevant disclosures.

Vanessa Noonan, MSc, PhD, PTRick Hansen Institute This author has no relevant disclosures.Nader Fallah, PhDRick Hansen Institute This author has no relevant disclosures.Andrei Krassioukov, MD, PhD, FRCPCInternational Collaboration on Repair Discoveries (Icord), Faculty of Medicine, University of British Columbia This author has the following disclosures:

Research Support Other (see below)

ONGOING RESEARCH SUPPORT 1. Craig H. Neilsen Foundation QOL Project Grants. Title: Motherhood after spinal cord injury: lactation, breastfeeding, and autonomic dysreflexia. Period: 2016-2017 ROLE: PI

2. Heart and Stroke GIA 2016/17. Title: When are blood vessels “ready to rupture”? Cerebrovascular health following spinal cord injury: from animal models to clinical practice. Period: 2016 – 2019 ROLE: PI

3. Pfizer Canada Inc. Title: A Phase II, Open-Label Exploratory Study Investigating the Efficacy of Toviaz for Treatment of Adult Patients with Spinal Cord Injury (SCI) with Neurogenic Detrusor Overactivity (NDO) for Amelioration of Autonomic Dysreflexia (AD). Period: Nov 2015 –Feb 2017 ROLE: PI

4. Rick Hansen Institute. Title: Development of a mobile app (telephone/iPod application) for emergency department physicians on recognition and management of life-threatening episodes of autonomic dysreflexia: “ABC of AD for the EM doc”. Period: Apr 2015-Dec 2016. ROLE: PI

5. Vancouver Foundation. Title: Vancouver Foundation Start-up Funds: Period: April 2015 – March 2017 ROLE: PI

6. Christopher and Dana Reeve Foundation. Title: Big Idea Cardiovascular Committee. Period: Feb 2015-Aug2015. ROLE: PI

7. Rick Hansen Institute/ RHI Pilot Studies - Optimizing Neurorecovery Following SCI. Title: Effect of epidural stimulation on cardiovascular control following spinal cord injury. Period: Mar 2015-Mar 2017.

ROLE: PI

8. Rick Hansen Foundation/International Collaboration On Repair Discoveries (ICORD)/Seed Grants. Title: Development of evidence-based guidelines for blood pressure management during iatrogenically-induced autonomic dysreflexia in those with spinal cord injury: the limits of cerebral autoregulation. Period: Apr 2014-Jun 2016. PI: Dr. Stacy Elliott. ROLE: Co-Investigator

9. Department of Defense USA. Title: Alleviating autonomic dysreflexia after spinal cord injury. Period: September 2014-August 2017. ROLE: PI

10. Craig H. Neilsen Foundation/ Neilsen Senior Research Grant. Title: Cardiac function after spinal cord injury: from bench to bedside. Period: July 2013-June 2017. ROLE: PI 11. Rick Hansen Institute. Title: Validation of the International Autonomic Standards for evaluation of individuals with chronic spinal cord injury. Period: March 2013- March 2017. ROLE: PI

12. Rick Hansen Foundation. Title: Improving Cardiovascular Health for Canadians Living with SCI: Effects of Exercise, sex Differences, and Targeted Clinical Education. Period: April 2012-March 2017. ROLE: PI

13. Rick Hansen Institute / Operating Grant. Title: BOTOX treatment for neurogenic detrusor hyperreflexia and prevention of autonomic dysreflexia following spinal cord injury. Period: July 2012 – Jan. 2017. ROLE: PI

14. Canadian Institutes of Health Research (CIHR) / Chronic disease risk and intervention strategies team grant. Title: Improving cardiovascular health for Canadians living with spinal cord injury: effects of exercise and targeted education. Period: Dec. 2011-Nov. 2016. ROLE: PI

15. Craig H. Neilsen Foundation/Christopher and Dana Reeve Foundation. Title: Recovery of cardiovascular function with epidural stimulation after human spinal cord injury. Period: January 2015-December 2017. PI: Dr. Susan Harkema ROLE: Co-Investigator

16. Canadian Institutes of Health Research (CIHR) / Operating grant. Title: Beyond VO2peak: Understanding exercise-induced changes in cardiovascular function after

stroke. Period: 2011-2015. PI: Dr. J. Eng ROLE: Co-Investigator

17. International Spinal Research Trust / Operating grant. Title: Peripheral Sympathetic and sensory plasticity in bladder and bowel circuitry in chronic spinal cord injury. Period: Jan. 2011-Aug. 2014. PI: Dr. M. Ramer ROLE: Co-Investigator

18. Rick Hansen Institute Start Up Funds. Title: Rick Hansen Institute Start-Up Funds. Period: March 2007 – March 2020. ROLE: PI

OTHER: Coloplast and WellSpect

30: Longitudinal recovery and reduced costs after 120 sessions of locomotor training for motor incomplete spinal cord injury Wednesday, May 02, 2018 09:30 AM - 10:30 AMLearning Objectives:1. understand the time course of clinically meaningful recovery in human incomplete SCI and the potential impact of therapy caps on optimal recovery

Participants:1Morrison S, 2Lorenz D, 3Eskay C, 4Forrest G, 5Basso D1Shepherd Center, Inc , Atlanta , GA, USA; 2University of Louisville , Louisville , KY, USA; 3Wexner Medical Center, Outpatient Neurological Clinic, the Ohio State University, , Columbus , OH, USA; 4Kessler Foundation Research Center, Human Performance and Movement Analysis Laboratory , West Orange , NJ, USA; 5The Ohio State University , Columbus , OH, USASarah Morrison, PT, MBA, MHAShepherd Center, Inc Bio:Sarah Morrison is the President and CEO at Shepherd Center in Atlanta, GA. Shepherd Center is a 152-bed private, not-for-profit specialty care hospital for persons with spinal cord injury, brain injury and other neurological disorders. As CEO, Sarah is responsible for all activities and operations within the hospital. Sarah is well known in the healthcare community, having written many peer-reviewed publications, conducted over 40 invited lectures nationally and internationally and actively participated in 8 funded research studies. In 2013, Sarah received the award for Clinical Excellence in Neurology from the Neurological Section of the American Physical Therapy Association. Sarah received her bachelor’s degree in Physical Therapy from the University of Miami, where she graduated summa cum laude. She received an MBA and

MHA from Georgia State University, where she received the Max G. Holland scholarship for the highest grade point average in the graduate business program.Education:University of Miami (Coral Gables, FL), BS 1984 Physical Therapy Georgia State University (Atlanta, GA), MS 2016, MBA Georgia State University (Atlanta, GA), MS 2017, MHAThis author has no relevant disclosures.Douglas Lorenz, PhDUniversity of Louisville This author has no relevant disclosures.Carol P. Eskay, PT, MPT Eskay, PT, MPTWexner Medical Center, Outpatient Neurological Clinic, the Ohio State University, This author has no relevant disclosures.Gail F Forrest, PhDKessler Foundation Research Center, Human Performance and Movement Analysis Laboratory This author has no relevant disclosures.D Michele Basso, Ed.D., PTThe Ohio State University Bio:D. Michele Basso Ed.D., PT received a B.S. in Physical Therapy from the University of Utah in 1984, an M.A. and Ed.D in Motor Learning from Teachers College, Columbia University in 1986 and 1991, respectively. She completed two postdoctoral fellowships – one with Michael Goldberger, Ph.D., in recovery of function after SCI at Medical College of Pennsylvania, 1991-1992, and one with Jacqueline Bresnahan, Ph.D., and Michael Beattie, Ph.D., in mechanisms of recovery at The Ohio State University, 1992-1996. Dr. Basso is currently a professor and Director of Research for the School of Health and Rehabilitation Sciences at The Ohio State University. Dr. Basso has two research initiatives for spinal cord injury (SCI) – projects that use a basic science approach and human studies that translate to the clinic. The basic science projects focus on the cellular and molecular mechanisms of sensory and motor recovery after SCI. Recent studies focus on the role of inflammatory mechanisms in impeding exercise-induced improvements in function after SCI. The activity-based interventions used in experimental SCI closely match those used in neurorehabilitation. The clinical and translational initiatives include participating in the first multicenter clinical trial in neurorehabilitation for SCI (SCILT) as well as directing the Neurorecovery Network Center at Ohio State University. Currently funded projects are the first in-person study of task-specific training derived in our basic science experimental models. Grant funding to support the clinical and basic science projects includes NIH, DOD, Craig H. Neilsen Foundation and Christopher and Dana Reeve Foundation through a cooperative agreement from the U.S. Administration for Community Living at the Department of Health and Human Services. She and her colleagues at Ohio State were recognized as a Center of Excellence for SCI research by NIH for 10 years which has continued through the Craig H. Neilsen Foundation. They train SCI scientists in practice standards for experimental SCI. Dr. Basso serves on study sections for NIH, Wings For Life Foundation and Shriner’s Foundation. She is a Councilor for the National Neurotrauma Society and is appointed to the Research Committee for the Association of Schools of Allied Health Professions.

Education:University of Utah, BS, 1984, Physical Therapy

Teachers College, Columbia University, MA, 1986, Motor Learning

Teachers College, Columbia University, Ed.D. 1991, Motor Learning

Medical College of Pennsylvania (now Drexel University), Postdoc, 1991, Spinal Cord Injury

The Ohio State University, Postdoc, 1992, Spinal Cord Injury

This author has the following disclosures: Research Support

NIH, Craig H. Neilsen, Christopher & Dana Reeve Foundation

31The effects of activity-based training on urinary tract function following spinal cord injuryWednesday, May 02, 2018 09:30 AM - 10:30 AMLearning Objectives:Learning Objective: To describe the impact of activity-based training on bladder outcomes after SCI.

Participants:1Hubscher C, 2Herrity A, 1Montgomery L, 3Angeli C, 2Harkema S1University of Louisville, Department of Anatomical Sciences and Neurobiology , Louisville , KY, U.s.a.; 2University of Louisville, Department of Neurological Surgery , Louisville , KY, U.s.a.; 3University of Louisville, Frazier Rehab Institute , Louisville , KY, U.s.a.Charles Hubscher, PhDUniversity of Louisville, Department of Anatomical Sciences and Neurobiology Bio:Title: Charles H. Hubscher, Ph.D. Professor and Vice Chair Director of Graduate Studies Department Anatomical Sciences & Neurobiology University of Louisville School of Medicine

Bio: Dr. Charles Hubscher received his Bachelor of Science degrees in Biochemistry (1986) from Concordia University and in Psychology (1988) from McGill University in Montreal, Canada. He earned his Master of Science degree (1990) and Doctor of Philosophy degree (1994) in Neuroscience from the Psychology Department at Florida State University in Tallahassee. He held an Assistant Scientist position at the University of Florida in Gainesville in the Department of Physiological Sciences before coming to the University of Louisville as a faculty member in

the Department of Anatomical Sciences and Neurobiology in 2001. Dr. Hubscher currently holds the rank of Professor at the University Of Louisville School Of Medicine and serves as Vice Chair and Director of Graduate Studies for the Department of Anatomical Sciences and Neurobiology. He has an Associate appointment in the Department of Neurological Surgery and is a member of the Kentucky Spinal Cord Injury Research Center. His research on spinal cord injury is funded by grants from agencies that include the National Institutes of Health, the Department of Defense, and several private foundations. Specific research expertise includes the areas of bladder, bowel and sexual functions as well as chronic spinal cord injury related pain. Education:Concordia University BS 1986 Biochemistry McGill University BS 1988 Psychology Florida State University MS 1990 Neuroscience Florida State University PhD 1994 Neuroscience University of Florida 1994-1996 Postdoctoral TrainingThis author has no relevant disclosures.April Herrity, DC, PhDUniversity of Louisville, Department of Neurological Surgery This author has no relevant disclosures.Lynnette Montgomery, PT, PhDUniversity of Louisville, Department of Anatomical Sciences and Neurobiology This author has no relevant disclosures.Claudia Angeli, PhDUniversity of Louisville, Frazier Rehab Institute This author has no relevant disclosures.Susan Harkema, PhDUniversity of Louisville, Department of Neurological Surgery This author has no relevant disclosures.

32Development of an Educational Pamphlet about the ISNCSCI Examination for Young Patients Wednesday, May 02, 2018 09:30 AM - 10:30 AMLearning Objectives:Objective: The learner will be able to describe the purpose and relevance of the development of a patient-education pamphlet designed to explain the ISNCSCI examination in non-technical, child-friendly terminology.

Participants:Scharff K, Johnson DShriners Hospitals for Children - Philadelphia , Philadelphia , PA, USAKimberly Scharff, PT, DPT, PCSShriners Hospitals for Children - Philadelphia

Bio:Kimberly A. Scharff, PT, DPT, PCS is a physical therapist at Shriners Hospitals for Children – Philadelphia. She received a Bachelor of Science degree in Biology from Villanova University, a Master of Education degree from Cabrini College, and a Doctorate of Physical Therapy degree from Drexel University in 2006. She is a Pediatric Clinical Specialist as designated by the American Physical Therapy Association. She has ten years of experience evaluating and treating children and youth with spinal cord injuries. She is the current co-chair of the ASIA Pediatrics Committee. Education:Drexel University, Philadelphia, PA Doctorate of Physical Therapy, May 2006

Cabrini College, Radnor, PA Master of Education, August 2000

Villanova University, Villanova, PA Bachelor of Science in Biology, May 1996 This author has no relevant disclosures.Dana Johnson, PT, DPTShriners Hospitals for Children - Philadelphia Bio:Dana R. Johnson, PT, DPT is a senior physical therapist and Spinal Cord Injury Team Leader at Shriners Hospitals for Children – Philadelphia. She received a Bachelor of Science degree in Mathematics from Spelman College in 1998, and a Doctorate of Physical Therapy degree from Temple University in 2003. She has twelve years of experience evaluating and treating children and youth with spinal cord injuries and is a member of the American Spinal Injury Association. Education:Temple University, Philadelphia, PA Doctorate of Physical Therapy, July 2003

Spelman College, Atlanta, GA Bachelor of Science in Mathematics, May 1998 This author has no relevant disclosures.

33Facilitating Developmental Movement Patterns with the Use of a Body-Weight Supported Harness in Incomplete Spinal Cord Injury.Wednesday, May 02, 2018 09:30 AM - 10:30 AMLearning Objectives:To demonstrate the potential benefits of utilizing a body weight supported harness for developmental movement patterns, in the management of postural instability and spasticity related to incomplete spinal cord injury.

Participants:

Kenig NKessler Institute for Rehabilitation , West Orange , NJ, United statesNaama Kenig, PT, DPTKessler Institute for Rehabilitation Bio:Naama Kenig PT, DPT is a proficient physical therapist in the spinal cord injury unit at Kessler Institute for Rehabilitation in West Orange, NJ. Naama earned her doctorate degree from SUNY Downstate Medical Center in 2013. She has been working in Kessler since 2014 and has experience in treating stroke, spinal cord injury, and other neurologic conditions. Naama is a member of the American Physical Therapy Association, neurology section.

Education:CUNY College of Staten Island (New York) 2008-2010, Majored in Psychology SUNY Downstate Medical Center (New York) 2010-2013, BS and DPT in Physical Therapy This author has the following disclosures:

Other (see below)I am employed by Select Medical- Kessler Institute for Rehabilitation.

34Cardiovascular fitness responses to Body-Weight Support Treadmill Training and Arm-Crank Ergometry Training in Individual with Complete Motor Spinal Cord Injury: Randomized Control TrialWednesday, May 02, 2018 09:30 AM - 10:30 AMLearning Objectives:It is to investigate and compare the effects of a 6-month training program of two modalities of training including manually-assisted Body Weight-Supported Treadmill Training (BWSTT) and Arm-Cycle Ergometry Training (ACET) on the cardiovascular fitness in chronic motor complete spinal cord injury individuals.

Participants:1Alrashidi A, 2Hubli M, 3MacDonald M, 3Hick A, 4Ditor D, 5Craven C, 5Verrier M, 3Currie K, 1Krassioukov A1University of British Columbia , Vancouver , British co, Canada; 2University of Zurich , Zurich , , Switzerland; 3Mcmaster University , Hamilton , Ontario, Canada; 4Brock University , St. Catharines, , Ontario, Canada; 5University of Toronto , Toronto , Ontario, CanadaAbdullah Alrashidi, PT, MSc, Phd studentUniversity of British Columbia Bio:Abdullah is a senior physical therapist. Finished my BSc at King Saud University on 2004 where I practiced my profession at King Fahd Medical City, Rehabilitation Hospital, Physical Therapy department. On 2008, I received a scholarship from my employer to obtain Master degree. I finished my MSc at University of Pittsburgh on 2009. I returned to the same work where I worked as a senior physical therapist and the head of the acute setting. On September 2016, I started my Phd at the University of British Columbia, Experimental Medicine, Faculty of

Medicine. My PhD supervisor is Dr. Krassioukov a well-known researcher in cardiovascular/autonomic with spinal cord injury population. My research interest is studying the effect of different kind of exercises/Rehabilitation techniques on aerobic capacity with spinal cord population.Education:- BSc in physical therapy, 2004, King Saud University, Riaydh, KSA - MSc in Rehabilitation science, University of Pittsburgh, Pittsburgh, USA.This author has the following disclosures:

Research SupportPhD scholarship from King Fahd Medical City, Ministry of Health, Saudi Arabia.Michèle Hubli, PhDUniversity of Zurich This author has no relevant disclosures.Maureen MacDonald, PhDMcmaster University This author has no relevant disclosures.Audrey Hick, PhDMcmaster University This author has no relevant disclosures.Dave Ditor, PhDBrock University This author has no relevant disclosures.Cathy Craven, MDUniversity of Toronto This author has no relevant disclosures.Molly Verrier, Dip (P&OT), MHScUniversity of Toronto This author has no relevant disclosures.Katharine Currie, PhdMcmaster University This author has no relevant disclosures.Andrie Krassioukov, MD, PhDUniversity of British Columbia This author has the following disclosures:

Research SupportCanadian Institute for Health Research as principal investigator. Craig H. Neilsen Foundation as principal investigator.

35Quality of life in patients after a traumatic cervical spinal cord injury based on the severity and recovery of the neurological impairmentWednesday, May 02, 2018 09:30 AM - 10:30 AM

Learning Objectives:Discuss the relationship between neurological status and recovery, and long-term quality of life in patients with traumatic cervical SCI.

Participants:1Houle-Clermont G, 2Richard-Denis A, 2Thompson C, 2Mac-Thiong J1Université De Sherbrooke , Sherbrooke , Québec, Canada; 2Hôpital Du Sacré-Coeur De Montréal , Montréal , Québec, CanadaGabrielle Houle-Clermont, Université De Sherbrooke This author has no relevant disclosures.Andréane Richard-Denis, MD. MScHôpital Du Sacré-Coeur De Montréal This author has no relevant disclosures.Cynthia Thompson, Hôpital Du Sacré-Coeur De Montréal This author has no relevant disclosures.Jean-Marc Mac-Thiong, MD, PhDHôpital Du Sacré-Coeur De Montréal Bio:Jean-Marc Mac-Thiong, MD, PhD, is a clinician-scientist practicing as an orthopedic spine surgeon at the Hopital du Sacre-Coeur de Montreal, with a multidisciplinary background in spine surgery (MD, fellowship), biomedical sciences (MSc, PhD), and engineering (BEng). He is an associate professor of surgery and research director of the Orthopedics Division at Université de Montréal. He is Chairman of the Medtronic Research Chair in spinal trauma at Université de Montréal and in charge of the Rick Hansen Spinal Cord Injury Registry at Hopital du Sacre-Coeur de Montreal. He is Chair of the Spine/Acute care Committee at the American Spinal Injury Association. His research has been supported by the Canadian Funds for Innovation, Natural Sciences and Engineering Research Council of Canada, Department of the US Army, Fonds de recherche du Québec – Santé, Fonds de recherche du Québec – Nature et technologies, and Scoliosis Research Society. He has focused his research on acute predictors of the outcome after a traumatic spinal cord injury, and on the biomechanical and experimental characterization of traumatic spinal cord injury.Education:École Polytechnique de Montréal (Montréal, QC, Canada), B.Eng 1997 Mechanical engineering Université de Montréal (Montréal, QC, Canada), MS 2001 Biomedical sciences Université de Montréal (Montréal, QC, Canada), MD 2002 Medicine Université de Montréal (Montréal, QC, Canada), Residency 2007 Orthopedic surgery Université de Montréal (Montréal, QC, Canada), Ph.D 2008 Biomedical sciences Twin Cities Spine Center (Minneapolis, MN, US), Fellowship 2008 Spine surgery This author has no relevant disclosures.

36

CASE STUDY: The Impact of Urinary Symptoms and the Urine Microbiome in an individual that has changed from Intermittent to Suprapubic catheter Wednesday, May 02, 2018 09:30 AM - 10:30 AMLearning Objectives:-Review why an SCI patient would change from an intermittent to supraubic catheter -Discuss urinary symptoms while using an intermittent catheter or suprapubic catheter -Review the changes in urinalysis, cultures and microbiome.

Participants:1Rounds A, 1Ljungberg I, 2Groah S1Medstar Health Research Institute , Washington , DC, USA; 2Medstar National Rehabilitation Hospital , Washington , DC, USAAmanda Rounds, PhDcMedstar Health Research Institute Bio:Amanda K Rounds, PhDc is a Rehabilitation Science PhD candidate at George Mason University in Fairfax, VA. After completing her bachelors at George Mason University in Integrative Studies, she immediately started the PhD program for Rehabilitation Science where she has focused on individuals with neurological trauma such as Stroke and SCI and how these traumas alter perception. Amanda K Rounds joined the SCI research team in 2017 at National Rehabilitation Hospital in Washington, DC and has continued to explore perception in SCI patients and how urinary symptoms are perceived in relation to how they are actually measured. Education:Ph.D. Rehabilitation Science, August 2012- Present George Mason University Fairfax, Virginia

B.S. Integrative Studies Concentration: Life Sciences, August 2010-May 2012 George Mason University Fairfax, Virginia This author has no relevant disclosures.Inger Ljungberg, MPHMedstar Health Research Institute This author has no relevant disclosures.Suzanne Groah, MSPH, MDMedstar National Rehabilitation Hospital This author has no relevant disclosures.

37Larval Debridement Therapy of Sacral/Coccyx Pressure Ulcer in the Acute Rehabilitation Setting : Giving Their Lives for a Good Cause - Case ReportsWednesday, May 02, 2018 09:30 AM - 10:30 AMLearning Objectives:

To define LDT as a viable debridement option for the SCI population with sacral/coccyx Pressure ulcers in the Acute Rehabilitation setting.

Participants:Otsuji-Miwa N, Phillips E, Rece JMagee Rehabilitation Hospital , Philadelphia , Pennsylvan, USANaoko Otsuji-Miwa, RN, BSN, CRRN, CWOCN, CFCNMagee Rehabilitation Hospital Bio:Naoko Otsuji-Miwa, RN, BSN is a wound care nurse in the Magee Rehabilitation Hospital. She has been certified with wound, ostomy and continence nursing after she worked as a floor nurse for patients with spinal cord injury (SCI). she has also been certified with foot care and rehabilitation nursing to provide better services for SCI patients. She is interested in improving patients' care in an acute rehabilitation hospital for SCI patients.Education:Tokyo Municipal Fuchu Nursing School 1977- 1980

Community College of Philadelphia 1998-2000

Drexel University RN-BSN program 2000 - 2010

La Salle University, wound, ostomy and continence education program 2011-2012This author has no relevant disclosures.Everyn Phillips, MS, RD, LDN, CDEMagee Rehabilitation Hospital Education:9/95 to 5/98 Masters of Science in Health Education Saint Joseph's University, Philadelphia, PA. Thesis topic: Screening for Hip Fracture Risk in Older Adults

1/87 to 3/88 Coordinated Undergraduate Program in Clinical Dietetics Drexel University / Hospital of the University of Pennsylvania, Philadelphia, PA. Registered Dietitian 4/88 ADA# 719440

9/79 to 6/82 Bachelor of Science Degree in General Dietetics Drexel University, Philadelphia, PA This author has no relevant disclosures.Julianna Rece, RN, MSN, CWOCNMagee Rehabilitation Hospital Education:aSalle University, Philadelphia, PA Post-Graduate Certificate: Wound, Ostomy, Continence Nurse Education Program, May, 2000 Thomas Jefferson University, Philadelphia, PA -M.S. Nursing, May, 1992 University of North Carolina – Greensboro, Greensboro, NC

-B.S. Nursing, May, 1984 University of North Carolina – Greensboro, Greensboro, NC -B.S. History, May, 1982 This author has no relevant disclosures.

38Predictive equations over-estimate the resting energy expenditure in spinal cord injured patients who are dependent on invasive ventilation support: a case series.Wednesday, May 02, 2018 09:30 AM - 10:30 AMLearning Objectives:The objective of this case-series is to compare the measured resting metabolic rate (m-RMR) with estimated RMR (e-RMR) using four commonly used predictive equations (Harris-Benedicts, Mifflin-St. Jeor, Oxford-Henry and Schofield) in spinal cord injured patients required mechanical ventilation.

Participants:Wong S, Subong P, Ahmed W, Derry F, Graham A, Saif M, Belci MNational Spinal Injuries Centre, Stoke Mandeville Hospital , Aylesbury , , United kingdomSamford Wong, MSc (Med Sci)., PhD., RDNational Spinal Injuries Centre, Stoke Mandeville Hospital Bio:Samford Wong is NSIC Dietetic Lead in Research / Lead Dietitian, National Spinal Injuries Centre, Stoke Mandeville Hospital Department of Nutrition and Dietetics, Stoke Mandeville Hospital, Buckinghamshire Healthcare NHS Trust, Aylesbury HP21 8AL; Tel: 01296 315775Education:2004: BSc (Hons)., RD; 2006: MSc (Med Sci); 2010; Dip Adv Diet: 2011; 2012: MPhil / PhD PTLLS: 2013; CMS: 2014This author has the following disclosures:

Research SupportResearch grant form Yakult HonshaPaul Subong, RNNational Spinal Injuries Centre, Stoke Mandeville Hospital This author has no relevant disclosures.Wail Ahmed, MRCSNational Spinal Injuries Centre, Stoke Mandeville Hospital This author has no relevant disclosures.Fadel Derry, FRCSNational Spinal Injuries Centre, Stoke Mandeville Hospital

This author has no relevant disclosures.Allison Graham, MD., FRCPNational Spinal Injuries Centre, Stoke Mandeville Hospital This author has no relevant disclosures.Mofid Saif, MD., FRCP., FRCSNational Spinal Injuries Centre, Stoke Mandeville Hospital This author has no relevant disclosures.Maurizio Belci, MRCS., FRCPNational Spinal Injuries Centre, Stoke Mandeville Hospital This author has no relevant disclosures.

39Effects of Neuromuscular Electrical Stimulation on Upper Extremity Recovery in Individuals with Spinal Cord InjuryWednesday, May 02, 2018 09:30 AM - 10:30 AMLearning Objectives:Learning Objective: To discuss the effects of a task specific upper extremity NMES program on recovery of upper extremity kinematics and upper extremity motor and sensory measures.

Participants:1Nalle E, 1Pfeiffer J, 2Herrity A, 3Shogren C, 4Harkema S1Frazier Rehab Institute , Louisville , KY, United states; 2Department of Neurological Surgery, University of Louisville , Louisville , KY, United states; 3Courage Kenny Rehabilitation Institute, a Part of Allina Health , Minneapolis , MN, United states; 4Professor and Associate Director, Kentucky Spinal Cord Injury Research Center, University of Louisville Owsley B. Frazier Chair in Neurological Rehabilitation Research Director, Frazier Rehab Institute Director of the Neurorecovery Network , Louisville , KY, United statesErin Nalle, MS, OTR/L, CBISFrazier Rehab Institute Bio:Erin Nalle, MS, OTR/L, CBIS has been a practicing occupational therapist for seven years. She is currently a Research Occupational Therapist with the spinal cord program at Frazier Rehab Institute in Louisville, Kentucky. Prior to August of 2015, she worked at Cardinal Hill Rehabilitation Hospital in Lexington, Kentucky, where she specialized in working with patients that had experienced a CVA or TBI, and received her certified brain injury specialist certification. She received her Master of Science, Occupational Therapy from Eastern Kentucky University in Richmond, Kentucky. Erin is currently an active member of the Kentucky Occupational Therapy Association. Her clinical interests include neurological rehabilitation and research for evidence-based practice and neuromuscular electrical stimulation.Education:Eastern Kentucky University (Richmond, KY) 08/2007-07/2010, MS, Occupational Therapy

University of Kentucky (Lexington, KY) 08/2002- 05/2006, B.A. Psychology

This author has no relevant disclosures.Julie Pfeiffer, PT, DPTFrazier Rehab Institute This author has no relevant disclosures.April Herrity, DC, PhDDepartment of Neurological Surgery, University of Louisville This author has no relevant disclosures.Carrie Shogren, OTR/LCourage Kenny Rehabilitation Institute, a Part of Allina Health This author has no relevant disclosures.Susan Harkema, PhDProfessor and Associate Director, Kentucky Spinal Cord Injury Research Center, University of Louisville Owsley B. Frazier Chair in Neurological Rehabilitation Research Director, Frazier Rehab Institute Director of the Neurorecovery Network This author has the following disclosures:

Research SupportSusan Harkema, PhD, Professor and Associate Scientific Director, U of L’s KSCIRC, Dir. of research at FRI, Dir. of CDRF’s Neurorecovery Network and receives a salary. Her research is funded by the National Institutes of Health, the Leona M and Harry B Helmsley Charitable Trust, the CDRF, the Craig H Neilsen Foundation, The Kessler Foundation Research Center, and the Kentucky Spinal Cord and Head Injury Research Trust. Her research receives support from FRI and the Commonwealth of Kentucky Challenge for Excellence Trust Fund.

40An examination of the adapted Rotterdam Transition Profile and transition outcomes for young adults with SCIWednesday, May 02, 2018 09:30 AM - 10:30 AMLearning Objectives:Objective 1: Describe transition outcomes and early strategies to examine the validity and reliability of an adapted tool.

Participants:Ryerson Espino S, Kalinich T, Anderson L, Kelly E, Zebracki KShriners Hospitals for Children Chicago , Chicago , IL, USASusan Ryerson Espino, PhDShriners Hospitals for Children Chicago Bio:Dr. Ryerson Espino is a practicing community psychologist, researcher and program evaluator. As part of the Shriners Scientific staff, she is responsible for developing, promoting, and conducting interdisciplinary pediatric rehabilitation research related to patient populations including those with spinal cord injury, cerebral palsy, spina bifida, and osteogenesis imperfecta. She has particular interests in research, evaluation and program development work that involve consumer collaboration and emphasize quality of life.

Education:Macalester College (Saint Paul, MN), BA 1991-1993 Anthropology, Latin American Studies with minor in Spanish

University of Illinois at Chicago (Chicago, IL), MA 2001 Community and Prevention Research, Department of Psychology

University of Illinois at Chicago (Chicago, IL), PhD 2001 Community and Prevention Research, Department of Psychology with minor in Statistics, Methods & Measurement This author has the following disclosures:

Research SupportStaff, Shriners Hospitals for Children ChicagoTyler Kalinich, Shriners Hospitals for Children Chicago This author has the following disclosures:

Other (see below)Intern for Shriners Hospitals for Children ChicagoLara Anderson, Shriners Hospitals for Children Chicago This author has the following disclosures:

ConsultantResearch assistant for Shriners Hospitals for Children ChicagoErin Kelly, PhDShriners Hospitals for Children Chicago This author has the following disclosures:

Consultant Other (see below)

Scientific Staff and Consultant, Shriners Hospitals for Children ChicagoKathy Zebracki, PhDShriners Hospitals for Children Chicago This author has the following disclosures:

Research SupportStaff, Shriners Hospitals for Children Chicago

41Identifying propulsion and non-propulsion activity in manual wheelchair users with spinal cord injury in their free-living environments using wearable inertial sensorsWednesday, May 02, 2018 09:30 AM - 10:30 AMLearning Objectives:1. Identify wheelchair propulsion from non-propulsion physical activity in manual wheelchair users in their natural environment using wearable sensors.

Participants:Fortune E, Cloud B, Madansingh S, Murphree D, Zhao K, Morrow MMayo Clinic , Rochester , Minnesota, United statesEmma Fortune, PhDMayo Clinic Bio:Emma Fortune, PhD, is a Research Associate in the Health Care Systems Engineering group in the Mayo Clinic Department of Health Sciences Research, and an Assistant Professor of Biomedical Engineering and Health Care Systems Engineering in the Mayo Clinic Graduate School in Rochester, Minnesota, USA. After receiving her Bachelor’s degree in Electrical Engineering with a focus on Biomedical Engineering from University College Dublin in Ireland in 2005, Fortune completed her research internship in Pharmacology at Duke University Medical Center in Durham, North Carolina in 2008 and earned her Doctoral (Biomedical Engineering) degree at University College Dublin in 2010. She then completed her Research Fellowships in Biomechanics and Wearable Sensor research in Intel as part of the Technology Research for Independent Living Centre in Ireland in 2011 and in the Motion Analysis Lab in the Department of Orthopedic Surgery at the Mayo Clinic in Rochester, Minnesota in 2016. Dr. Fortune has research funding support from the NIH and Neilsen Foundation. She studies the use of wearable sensors to measure and evaluate real world lower extremity function in older adults, and real world upper extremity function in humans after spinal cord injury, with an interest in developing outcome measures to assess and track functional recovery.Education:University College Dublin (Dublin, Ireland), BS 2001-2005 Electrical Engineering

Duke University Medical Center (Durham, NC, USA), Research Internship 2007-2008 Pharmacology

University College Dublin (Dublin, Ireland), PhD 2005-2010 Biomedical Engineering

Intel (Kildare, Ireland)/Technology Research for Independent Living Center (Dublin, Ireland), Postdoctoral Research Fellowship 2010-2011 Biomechanics and Wearable Sensor Technology

Mayo Clinic (Rochester, MN), Postdoctoral Research Fellowship 2011-2014 Biomechanics and Wearable Sensor Technology

Mayo Clinic (Rochester, MN), Senior Postdoctoral Research Fellowship 2014-2016 Biomechanics and Wearable Sensor Technology This author has the following disclosures:

Research SupportDr. Fortune is employed by Mayo Clinic Department of Health Sciences Research as an Assistant Professor and a Research Associate and receives a salary. The work being presented is supported by the Mayo Clinic Rehabilitation Medicine Research Center, on behalf of the Craig H. Neilsen Fund for Spinal Cord Injury Care and Research Honoring Robert D. Brown Jr., M.D.

Beth Cloud, PT, DPT, PhDMayo Clinic This author has the following disclosures:

Research SupportDr. Cloud is employed my Mayo Clinic as a Physical Therapy Educator and Assistant Professor and receives a salary. The work being presented is supported by the Mayo Clinic Rehabilitation Medicine Research Center, on behalf of the Craig H. Neilsen Fund for Spinal Cord Injury Care and Research Honoring Robert D. Brown Jr., M.D.Stefan Madansingh, PhDMayo Clinic This author has the following disclosures:

Research Support Consultant

Dr. Madansingh is employed my Mayo Clinic as a Research Fellow and receives a salary. He is employed as a consultant to iShoe, Inc., a medical device small-business focused upon falls risk management in elderly populations. The work being presented is supported by the Mayo Clinic Rehabilitation Medicine Research Center, on behalf of the Craig H. Neilsen Fund for Spinal Cord Injury Care and Research Honoring Robert D. Brown Jr., M.D.Dennis Murphree, PhDMayo Clinic This author has the following disclosures:

Research SupportDr. Murphree is employed by Mayo Clinic Department of Health Sciences Research as an Assistant Professor and a Research Associate and receives a salary. He received an equipment donation from the NVIDIA Corporation of four graphical processing units (GPU’s). The GPU’s are used solely in the employ of speeding up calculations necessary to perform this research, but are unrelated to either the study or its outcomes. The work being presented is supported by the Mayo Clinic Rehabilitation Medicine Research Center, on behalf of the Craig H. Neilsen Fund for Spinal Cord Injury Care and Research Honoring Robert D. Brown Jr., M.D.Kristin Zhao, PhDMayo Clinic This author has the following disclosures:

Research SupportDr. Zhao is employed by Mayo Clinic Department of Physical Medicine and Rehabilitation as an Associate Consultant II and receives a salary. The work being presented is supported by the Mayo Clinic Rehabilitation Medicine Research Center, on behalf of the Craig H. Neilsen Fund for Spinal Cord Injury Care and Research Honoring Robert D. Brown Jr., M.D.Melissa Morrow, PhDMayo Clinic This author has the following disclosures:

Research SupportDr. Morrow is employed by Mayo Clinic Department of Health Sciences Research as an Associate Consultant I and receives a salary. The work being presented is supported by the Mayo

Clinic Rehabilitation Medicine Research Center, on behalf of the Craig H. Neilsen Fund for Spinal Cord Injury Care and Research Honoring Robert D. Brown Jr., M.D.

42Sources of Injustice among Individuals Living with Spinal Cord InjuryWednesday, May 02, 2018 09:30 AM - 10:30 AMLearning Objectives:Upon completion of this session, the participant will be able to discuss injustice perception and its application to the SCI population.

Participants:1Monden K, 1Philippus A, 2Trost Z1Craig Hospital , Englewood , CO, USA; 2University of Alabama at Birmingham , Birmingham , AL, USAKimberley Monden, PhDCraig Hospital Bio:Kimberley R. Monden, PhD, is a Principal Investigator in the Research Department at Craig Hospital. After completing her Bachelor’s degree in Psychology and Master’s degrees in Counseling Psychology, with a focus on positive psychology, Dr. Monden earned her Doctoral degree in Counseling Psychology at the University of Kansas in 2009. She completed her pre-doctoral internship in Clinical Psychology at the University of Kansas Medical Center in Kansas City, KS and Post-Doctoral Fellowship in Health Psychology and Integrated Primary Care at the University of Wisconsin Hospital and Clinics and Access Community Health Centers in Madison, Wisconsin. Dr. Monden is a Licensed Psychologist with clinical experience in health and rehabilitation psychology. She serves on the Executive Committee of Division 22 (Rehabilitation Psychology) of the American Psychological Association as Treasurer and Past Chair of the Communications Committee. Dr. Monden has research funding support for NIDILLR and the Craig Hospital Foundation. She studies perceptions of injustice and resilience following traumatic injury with an interest in improving quality of life and long-term psychosocial outcomes after injury. Education:Avila University (Kansas City, MO), BA, Psychology, 2002

University of Kansas (Lawrence, KS), MS, Counseling Psychology, 2005

University of Kansas (Lawrence, KS), PhD, Counseling Psychology, 2009

University of Kansas Medical Center (Kansas City, KS), Pre-Doctoral Internship, Clinical Psychology, 2009

University of Madison Hospital & Clinics and Access Community Health Centers (Madison, WI), Post-Doctoral Fellowship, Health Psychology & Integrated Primary Care 2010This author has the following disclosures:

Research SupportAngie Philippus, BACraig Hospital This author has the following disclosures:

Research SupportZina Trost, PhDUniversity of Alabama at Birmingham This author has no relevant disclosures.

43Targeting urological improvements with spinal cord epidural stimulation after spinal cord injuryWednesday, May 02, 2018 09:30 AM - 10:30 AMLearning Objectives:Learning Objective: To describe the clinical implications of spinal cord epidural stimulation on recovery of bladder function after SCI.

Participants:1Herrity A, 2Hubscher C, 3Angeli C, 1Rejc E, 1Ferreira C, 1Harkema S1University of Louisville, Department of Neurological Surgery , Louisville , KY, U.s.a.; 2University of Louisville, Department of Anatomical Sciences and Neurobiology , Louisville , KY, U.s.a.; 3University of Louisville, Frazier Rehab Institute , Louisville , KY, U.s.a.April Herrity, DC, PhDUniversity of Louisville, Department of Neurological Surgery Bio:April Herrity, DC, PhD, is an Assistant Professor at the University of Louisville, Department of Neurological Surgery. She received her doctorate in Anatomical Sciences and Neurobiology from the University of Louisville in 2014. Her work examined the role of the vagus nerve after spinal cord injury and its input to the bladder and bowel in rodents. During her PhD candidacy, she received the National Institutes of Health F31, Ruth L. Kirschstein National Research Service Award (NRSA). April’s current research work is focused on understanding the impact of activity-based training and spinal cord epidural stimulation on the recovery of bladder, bowel and sexual function after human spinal cord injury. Her current professional experience includes: Lead Regulatory Coordinator for all Urogenital and Bowel studies, Director of Project Operations for the Kentucky Spinal Cord Injury Research Center’s Data Safety and Monitoring Board, and Manager and co-Director of the Urogenital and Bowel Core Laboratory. April also graduated with her Doctor of Chiropractic degree in 2003 from Cleveland Chiropractic College of Los Angeles, California and continues to work with patients part-time in Louisville, Kentucky.Education:University of New Mexico, Albuquerque, NM BS 1998 Bilingual Education Cleveland Chiropractic College, Los Angeles, CA DC 2003 Chiropractic University of Louisville, Louisville, KY, MS 2011 Anatomy & Neurobiology University of Louisville, Louisville, KY, PhD 2014 Anatomy & Neurobiology

This author has no relevant disclosures.Charles Hubscher, PhDUniversity of Louisville, Department of Anatomical Sciences and Neurobiology This author has no relevant disclosures.Claudia Angeli, PhDUniversity of Louisville, Frazier Rehab Institute This author has no relevant disclosures.Enrico Rejc, PhDUniversity of Louisville, Department of Neurological Surgery This author has no relevant disclosures.Christie Ferreira, BSUniversity of Louisville, Department of Neurological Surgery This author has no relevant disclosures.Susan Harkema, PhDUniversity of Louisville, Department of Neurological Surgery This author has no relevant disclosures.

44Influence of a posterior ligamentous complex injury on the mechanical condition of the spinal cord during flexionWednesday, May 02, 2018 09:30 AM - 10:30 AMLearning Objectives:To investigate the importance of post-traumatic immobilisation and stabilisation in the management of injured patients.

Participants:1Eric W, 1Hagen J, 1Beauséjour M, 2Mac-Thiong J, 3Arnoux P, 1Petit Y1École De Technologie Supérieure , Montreal , Quebec, Canada; 2University of Montreal , Montreal , Quebec, Canada; 3Aix-Marseille University , Marseille , Provence, FranceWagnac Eric, PhDÉcole De Technologie Supérieure This author has no relevant disclosures.Jérémy Hagen, M.A.Sc.École De Technologie Supérieure This author has no relevant disclosures.Marie-Hélène Beauséjour, PhD candidateÉcole De Technologie Supérieure This author has no relevant disclosures.Jean-Marc Mac-Thiong, MD, PhDUniversity of Montreal This author has the following disclosures:

Shareholder

Spinologics inc.Pierre-Jean Arnoux, PhDAix-Marseille University This author has no relevant disclosures.Yvan Petit, PhDÉcole De Technologie Supérieure Bio:Yvan Petit is professor in mechanical engineering at École de technologie supérieure (ÉTS) since 2003. He has a thorough expertise in the fields of biomechanical modeling and of the mechanical design of medical and protective devices. He is head of the Canada Research Chair on Engineering Innovations in Spinal Trauma that is dedicated to the development of sophisticated tools (numerical and experimental) to better understand, protect and treat traumatic spinal and spinal cord injuries. He is also head of the imaging and orthopaedics research laboratory of at Hôpital du Sacré-Coeur de Montréal (LIO-HSCM. He is also co-founder and member of the scientific committee of the International Research Lab on Imaging and Biomechanics of the Spine (iLab-Spine) dedicated to develop sophisticated numerical models to study spinal injuries and pathologies. Prof. Petit has published 4 US and Canadian patents (+2 under review) and more than 115 scientific papers in peers-reviewed journals or conference proceedings.Education:École Polytechnique de Montréal, B.eng, 1988-1993, Mechanical Engineering École Polytechnique de Montréal, M.A.Sc, 1993-1995, Mechanical Engineering École Polytechnique de Montréal, PhD, 2000-2003, Biomedical Engineering Queen's University, Kingston ON, postdoctoral fellowship, 2003, Biomedical EngineeringThis author has no relevant disclosures.

45Quality of sleep and psychosocial functioning in pediatric-onset spinal cord injury over time.Wednesday, May 02, 2018 09:30 AM - 10:30 AMLearning Objectives:Identify how sleep quality changes over time for adults with pediatric-onset spinal cord injury and be able to list variables that increase the risk for poor sleep quality.

Participants:January A, Zebracki K, Chlan K, Vogel LShriners Hospitals for Children-Chicago , Chicago , IL, USAAlicia January, PhDShriners Hospitals for Children-Chicago Bio:Alicia M. January, PhD, is a licensed clinical psychologist and member of the scientific and medical staff at Shriners Hospital for Children, Chicago. She is also an Assistant Professor in the Department of Psychology at Purdue University Northwest. After receiving her bachelor’s degree in psychology from John Carroll University, January earned her Master’s and Doctoral degrees in clinical psychology with a focus on child development and statistics. She then

completed her postdoctoral training in pediatric rehabilitation through a collaboration with Marquette University and Shriners Hospital for Children and funding support from NIDDR/NIDILRR and Shriners Hospitals. January is an instructor and research mentor with a focus on multidisciplinary research in the area of assessment and pediatric rehabilitation outcomes. She is involved in a number of university committees, as well as a member of the Pediatric Committee of ASIA. She has presented at both national and international conferences, and has published several peer-reviewed manuscripts in the area of rehabilitation and outcomes research.Education:John Carroll University (2000-2004), B.S, Psychology Wayne State University (2006-2008), M.A., Clinical Psychology Advocate Illinois Masonic Medical Center (2011-2012), APA Clinical Internship Wayne State University (2008-2012), Ph.D., Clinical Psychology Shriners Hospitals for Children/Marquette University (2012- 2014), Postdoctoral Fellowship in Pediatric Rehabilitation Psychology This author has the following disclosures:

Research SupportAlicia M. January is an Assistant Investigator at Shriners Hospitals for Children, Chicago and an Assistant Professor at Purdue University Northwest and receives a salary, including grant funding from Shriners Hospitals for Children (grant # 84202).Kathy Zebracki, PhDShriners Hospitals for Children-Chicago This author has the following disclosures:

Research SupportKathy Zebracki is Director of Psychology at Shriners Hospitals for Children, Chicago and receives a salary, including grant funding from Shriners Hospitals for Children (grant # 324671). Kathleen Chlan, BAShriners Hospitals for Children-Chicago This author has the following disclosures:

Research SupportKathleen M. Chlan is a Research Specialist at Shriners Hospitals for Children, Chicago and receives a salary, including grant funding from Shriners Hospitals for Children (grant # 324671). Lawrence Vogel, MDShriners Hospitals for Children-Chicago This author has the following disclosures:

Research SupportLawrence Vogel was Chief of Pediatrics at Shriners Hospitals for Children, Chicago and received a salary

46Heterotopic Ossification after Traumatic Spinal Cord Injury: Use of NSAIDs for ProphylaxisWednesday, May 02, 2018 09:30 AM - 10:30 AM

Learning Objectives:After viewing this research, participants will be able to: Discuss the potential role of NSAIDs in the prevention of Heterotopic Ossification following Traumatic Spinal Cord Injury, and identify certain patients whom this strategy may be considered.

Participants:1Crew J, 1Pence B, 1McKenna S, 2Yurkiewicz S, 3Zakrasek E1Santa Clara Valley Medical Center , San Jose , California, United states; 2Stanford University , Palo Alto , CA, United states; 3Va Palo Alto Health Care System , Palo Alto , California, United statesJames Crew, MDSanta Clara Valley Medical Center Bio:Dr. James Crew has been faculty at Santa Clara Valley Medical Center (SCVMC) for eight years, following his training in PM&R and Spinal Cord Injury (SCI) Medicine at the University of Washington. In 2011, he was appointed the Chief of Spinal Cord Injury at SCVMC. This position includes program oversight of an Inpatient SCI Unit, and collaboration with the Rehab Trauma Center at SCVMC for early SCI management pre-rehabilitation including ventilator management. Dr. Crew is also closely involved with the outpatient clinics at SCVMC to ensure smooth clinical transition and management of patients with SCI across the continuum of care. Additionally, Dr. Crew was appointed Chair of PM&R at SCVMC in 2014, overseeing clinical operations for a moderately large sized inpatient and outpatient academic neurorehabilitation practice with CARF Accreditation in seven programs. While his clinical work has been focused on treating individuals with SCI in the acute care and inpatient rehabilitation settings, he is also boarded in Neuromuscular Medicine and is actively involved in electrodiagnostics in the inpatient and outpatient setting. His research experience has focused on optimizing function and quality of life after SCI. He has participated as a co-investigator in the Geron OPC1 Stem Cell trial in SCI. He has clinical research experience with biomechanical devices including as the co-PI of a safety and efficacy evaluation of the Ekso wearable exoskeletal device for those with SCI. He currently serves as the SCVMC site Co-PI for the Asterias Stem Cell Clinical Trial in SCI, and was the SCVMC site Co-PI for the Geron Stem Cell Clinical Trial in SCI. Further, he was the SCVMC site PI for the Asubio SUN13837 clinical trial in acute cervical SCI. In addition, he previously received funding through the American Spinal Injury Association Young Investigator Award for his project on the Treatment of Vitamin D Deficiency in Persons with SCI. Dr. Crew is also actively involved in residency training, currently Chair of the Stanford PM&R Research and Quality Committee and having served as site director at SCVMC for the Stanford University PM&R program. He is a member of the Graduate Medical Education Committee at SCVMC, and was recently appointed onto the CNS Council in AAPMR in 2017 as Vice Chair of Education. Dr. Crew is also interested in SCI patient advocacy, having joined the ASIA Health Advocacy Commitee in 2017.Education:Creighton University (Omaha, NE) 1996-2000, Bachelor of Arts, Philosophy, Summa Cum Laude

Creighton University Medical School (Omaha, NE) 2000-2004, Doctorate of Medicine

University of Washington (Seattle, WA) 2004-2005, Transitional Year Internship

University of Washington (Seattle, WA) 2005-2008, Physical Medicine and Rehabilitation Residency

University of Washington/VA Puget Sound Healthcare (Seattle, WA) 2008-2009, Spinal Cord Injury Medicine Fellowship This author has no relevant disclosures.Benjamin Pence, DOSanta Clara Valley Medical Center This author has no relevant disclosures.Stephen McKenna, MDSanta Clara Valley Medical Center This author has no relevant disclosures.Shara Yurkiewicz, MDStanford University This author has no relevant disclosures.Elissa Zakrasek, MDVa Palo Alto Health Care System This author has no relevant disclosures.

47The impact of the parcellation strategy on the topological organization of brain networks in spinal cord injury.Wednesday, May 02, 2018 09:30 AM - 10:30 AMLearning Objectives:Examine the impact of the parcellation template on quantitative network metrics utilized for studying qualities of resting-state brain networks in spinal cord injury.

Participants:1Kaushal M, 2Oni-Orisan A, 1Chen G, 1Kaushal W, 3Leschke J, 1Budde M, 4Schmit B, 1Li S, 1Muqeet V, 1Kurpad S1Medical College of Wisconsin , Wauwatosa , WI, USA; 2Ut Health Science Center at Houston , Houston , TX, USA; 3University of Minnesota , Minneapolis , MN, USA; 4Marquette University , Milwaukee , WI, USAMayank Kaushal, MBBS, MBAMedical College of Wisconsin Bio:Mayank Kaushal, MD, MBA, is presently a Postdoctoral Fellow in the Department of Neurosurgery at Medical College of Wisconsin, Milwaukee, USA. He received his Medical and Business degrees at the Government Medical College, Chandigarh, India and the Indian Institute of Management, Ahmedabad, India, respectively. He then worked as a Research Associate in the

Department of Biomedical Engineering at Marquette University, Milwaukee, USA. His area of research is the study of neural networks in humans after spinal cord injury and traumatic brain injury using resting-state functional magnetic resonance imaging. Education:Government Medical College, Chandigarh, India, MBBS 2005-2011 Medicine Indian Institute of Management, Ahmedabad, India, MBA 2011-2013 Business Administration This author has no relevant disclosures.Akin Oni-Orisan, MDUt Health Science Center at Houston This author has no relevant disclosures.Gang Chen, PhDMedical College of Wisconsin This author has no relevant disclosures.Wenjun Li Kaushal, PhDMedical College of Wisconsin This author has no relevant disclosures.Jack Leschke, MDUniversity of Minnesota This author has no relevant disclosures.Matthew Budde, PhDMedical College of Wisconsin This author has no relevant disclosures.Brian Schmit, Marquette University This author has no relevant disclosures.Shi-Jiang Li, PhDMedical College of Wisconsin This author has no relevant disclosures.Vaishnavi Muqeet, MDMedical College of Wisconsin This author has no relevant disclosures.Shekar Kurpad, MD, PhDMedical College of Wisconsin This author has no relevant disclosures.

48Case Study: A Patient with Intellectual Deficits due to Aarskog-Scott Syndrome demonstrates ability to make neurological and functional gains after suffering a traumatic Spinal Cord Injury Wednesday, May 02, 2018 09:30 AM - 10:30 AM

Participants:

Rapalo R, Cantwell JMount Sinai Rehab , New York , NY, USARoberto Rapalo, PT,DPTMount Sinai Rehab Bio:Roberto is a a Senior Physical Therapist at Mount Sinai Hospital. Roberto has worked with Spinal Cord Injuries in the acute, rehab and outpatient setting working with all levels of injury , different etiologies and age groups. Roberto Has participated in stem cell research as a primary blinded investigator for spinal cord injuries.Education:University at Buffalo, Bachelor of Science 2009 New York Medical College , Doctorate of Physical Therapist 2012This author has no relevant disclosures.Jessica Cantwell, OTR/LMount Sinai Rehab Bio:Jessica is a Senior Occupational Therapist at Mount Sinai Medical Center in New York City. After receiving her Bachelor’s degree in Kinesiology with a minor in Gerontology from the University of Illinois Champaign- Urbana in 2008, Cantwell earned a Masters in Occupational Therapy from Washington University in St. Louis School of Medicine. Cantwell has worked in various adult rehabilitation settings with the focus on neurological rehabilitation and the most recent four years on the Spinal Cord Injury unit at Mount Sinai Hospital.Education:Washington University in St. Louis School of Medicine, St. Louis, MO December 2011 Master of Science in Occupational Therapy

University of Illinois, Champaign-Urbana, IL May 2008 Bachelor of Science in Kinesiology; Minor in Gerontology This author has no relevant disclosures.

49Wide-pulse neuromuscular electrical stimulation compared to traditional NMES parameters for changes in muscle volume and fatigue.Wednesday, May 02, 2018 09:30 AM - 10:30 AMLearning Objectives:1.The objective is to evaluate the increase of the pulse of electrical stimulation for the longitudinal effect of training on muscle cross sectional area and muscle fatigue.

Participants:1Forrest G, 2Rejc E, 2Harkema S1Kessler Foundation , West Orange , NJ, USA; 2University of Lousiville , Lousiville , Kentucky, USA

Gail Forrest, Ph.DKessler Foundation Bio:Gail F Forrest, Ph.D, is currently an Associate Professor, Rutgers, Associate Director of the Human Performance and Engineering Laboratory, an Affiliated Faculty Department of Biomedical Engineering, New Jersey Institute of Technology, Newark, NJ, Member of the Graduate Faculty in Biomedical Science, Rutgers, Newark, NJ. Much of Dr Forrest's funded research is focused towards functional, neural and musculoskeletal recovery after SCI. Dr Forrest is currently funded by multiple grants from the National Institute on Disability and Rehabilitation Research, Christopher and Dana Reeve Foundation, Department of Defense, and the Craig H. Neilsen Foundation. Recently Dr Forrest received funding to study the long term adaptions of exoskeleton training on neural and musculoskeletal recovery for non ambulatory incomplete SCI. Education:Temple University, Philadelphia Ph.D. 1/2001 Biomechanics

Post Doctoral Fellow, Kessler Foundation 1/2001-12/2002 Biomechanics This author has no relevant disclosures.Enrica Rejc, Ph.DUniversity of Lousiville This author has no relevant disclosures.Susan Harkema, Ph.DUniversity of Lousiville This author has no relevant disclosures.

50Advancing Recovery after Spinal Cord Injury utilizing Lower Extremity Neuromuscular Electrical Stimulation Wednesday, May 02, 2018 09:30 AM - 10:30 AMLearning Objectives:Describe the therapeutic outcomes as a result of lower extremity (LE) neuromuscular electrical stimulation (NMES) for individuals with upper and lower motor neuron injuries.

Participants:1Oakley A, 2Herrity A, 1O'Brien K, 3Shogren C, 4Tefertiller C, 5Forrest G, 6Harkema S1Frazier Rehabilitation Institute , Louisville , Kentucky, United states; 2University of Louisville Kentucky Spinal Cord Injury Research Center , Louisville , Kentucky, United states; 3Courage Kenny Rehabilitation Institute , Minneapolis , Minnesota, United states; 4Craig Hospital , Englewood , Colorado, United states; 5Kessler Foundation , West Orange , New jersey, United states; 6Frazier Rehabilitation Institute; University of Louisville Kentucky Spinal Cord Injury Research Center , Louisville , Kentucky, United statesAmanda Oakley, PT, DPT, NCSFrazier Rehabilitation Institute

Bio:Amanda Oakley, PT, DPT, NCS has been a practicing physical therapist for eight years. She is currently the Research Physical Therapy Supervisor at Frazier Rehab Institute in Louisville, Kentucky. Prior to May of 2015, she worked at the International Center for Spinal Cord Injury (ICSCI) at Kennedy Krieger Institute and per diem at Johns Hopkins Children's Hospital. She received her Bachelor of Health Sciences and Doctorate of Physical Therapy from Creighton University in Omaha, Nebraska. She is a board certified Neurologic Clinical Specialist and her clinical interests include the delivery of activity based therapy, specifically neuromuscular electrical stimulation and locomotor training. Amanda is a member of the American Physical Therapy Association and the Neurology section. She is a clinical mentor within the NeuroRecovery Training Institute Neurlogical Clinical Residency program. Additionally, she assisted with the course development and served as a Team Instructor for the NeuroRecovery Training Institute Lower Extremity Neuromuscular Electrical Stimulation. She is experienced as a land and aquatic therapist for children and adults with neuromuscular diagnoses. Education:Creighton University: Doctor of Physical Therapy May 2009 Bachelor of Science in Health Sciences May 2009 This author has no relevant disclosures.April Herrity, PhDUniversity of Louisville Kentucky Spinal Cord Injury Research Center This author has no relevant disclosures.Kelly O'Brien, PT, DPT, NCSFrazier Rehabilitation Institute This author has no relevant disclosures.Carrie Shogren, OTR/LCourage Kenny Rehabilitation Institute This author has no relevant disclosures.Candy Tefertiller, PT, DPT, NCSCraig Hospital This author has no relevant disclosures.Gail Forrest, PhDKessler Foundation This author has no relevant disclosures.Susan Harkema, PhDFrazier Rehabilitation Institute; University of Louisville Kentucky Spinal Cord Injury Research Center This author has the following disclosures:

Other (see below)Dr. Harkema has financial relationships with Power NeuroRecovery and NeuroRecovery Education.

51

Pain, Depression, and Resilience and their Relation to Life Satisfaction in Spinal Cord Injury Wednesday, May 02, 2018 09:30 AM - 10:30 AMLearning Objectives:Identify the relation between pain, depression and resilience in SCI.

Participants:Taylor HTirr Memorial Hermann , Houston , Texas, USHeather Taylor, PhDTirr Memorial Hermann Bio:Dr. Heather Taylor is the Director for Spinal Cord Injury and Disability Research (SCIDR) at TIRR Memorial Hermann. She is also the former Associate Director for Research for the Center for Research on Women with Disabilities in the department of Physical Medicine and Rehabilitation at Baylor College of Medicine. Dr. Taylor has focused her research on health, motor recovery and learning, and psychosocial functioning with a strong emphasis on women and children with SCI. She has published widely and presented nationally and internationally on research in the context of SCI. Dr. Taylor is the current founder and Chair for the American Congress of Rehabilitation Medicine’s SCI Interdisciplinary Special Interest Group Women’s Health Task Force (ACRM SCI-ISIG WHTF) focusing on the unique concerns of women’s health after SCI. She is also the current Chair for the American Spinal Injury Association’s (ASIA) Pediatric Committee sharing her mission to improve the lives of children with SCI. Dr. Taylor is the project director for the Texas Model Spinal Cord Injury System. Additionally, she is principal investigator on multiple projects and subcontracts collaborating nationally on motor recovery, health, and appropriate measures for adults and children with SCI. Education:Ohio University, Athens, Ohio BA 08/1992 Psychology

Ohio University, Athens, Ohio MS 06/1994 Human and Consumer Sciences

Ohio University, Athens, Ohio MED 06/1994 Counseling

University of Houston, Houston, TX PHD 05/2001 Counseling Psychology

University of Texas Medical Branch, Galveston, TX Internship training 07/2001 Clinical Neuropsychology and Rehabilitation Internship

Baylor College of Medicine, Houston, TX Residency training 09/2002 Rehabilitation Psychology Postdoctoral Training This author has no relevant disclosures.

52Assessment of Trunk Muscle in Human Spinal Cord Injury:Discovery of Volitional Movement Below the Level of InjuryWednesday, May 02, 2018 09:30 AM - 10:30 AMLearning Objectives:Learning Objective: Describe new approach of assessing the trunk muscle activation, the Functional Neurophysiological Assessment, and compare to the International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI) exam, and the neuromuscular recovery scale (NRS).

Participants:1O'Brien K, 2Atkinson D, 1Ochsner J, 3Tolfo C, 2Harkema S, 4Wyles E1Frazier Rehab Institute , Louisville , KY, USA; 2University of Lousville , Louisville , KY, USA; 3Frazier Rehab , Louisville , KY, USA; 4University of Louisville , Louisville , KY, USAKelly O'Brien, PT, DPT, CNSFrazier Rehab Institute Bio:Kelly O’Brien, PT, DPT, NCS, is a research physical therapist at Frazier Rehabilitation Institute and University of Louisville in Louisville, Kentucky. She has been a practicing physical therapist for 4 years. After receiving her bachelors in health science and doctorate in physical therapy at the University of Maryville in St. Louis, she completed a residency in neurologic physical therapy at the Shepherd Center in partnership with Mercer University in Atlanta, Georgia. She then received her board-certified neurologic clinical specialty certification. She assisted with the course development and served as an instructor and presenter for the NeuroRecovery Training Institute Lower Extremity Neuromuscular Electrical Stimulation course in 2016. Dr. O’Brien is a member of the American Physical Therapy Association and the Academy of Neurologic Physical Therapy. Education:2010-2012 DPT, Maryville University of St. Louis, Missouri Major: Physical Therapy This author has the following disclosures:Darryn Atkinson, DPT, PhDUniversity of Lousville This author has the following disclosures:Jamie Ochsner, PTFrazier Rehab Institute This author has the following disclosures:Carie Tolfo, PT, CNSFrazier Rehab This author has the following disclosures:Susan Harkema, University of Lousville

This author has the following disclosures:Erin Wyles, University of Louisville This author has the following disclosures:

53“A D is not a D”: Identifying sources of neuromuscular and functional heterogeneity within an AIS D population.Wednesday, May 02, 2018 09:30 AM - 10:30 AMLearning Objectives:To identify and discuss sources of functional variability which are common within AIS classifications, as well as opportunities to improve measurement of neuromuscular function in incomplete SCI individuals

Participants:1Atkinson D, 2Schmidt Read M, 3Tefertiller C, 2watson E, 4Oakley A, 3Joyce M, 5Forrest G, 5Wojceihowski B, 6basso D, 7Sisto S, 1Harkema S, 1Behrman A1University of Louisville , Louisville , KY, United states; 2Magee Rehabilitation Hospital , Philadelphia , PA, United states; 3Craig Hospital , Denver , Colorado, United states; 4Frazier Rehab Institute , Louisville , Kentucky, United states; 5Kessler Rehab Institute , West Orange , New jersey, United states; 6The Ohio State University , Columbus , Ohio, United states; 7Stony Brook University , Stony Brook , New york, United statesDarryn Atkinson, PhD, PTUniversity of Louisville Bio:I began working in spinal cord injury rehabilitation as an inpatient physical therapist at The Institute for Research and Rehabilitation (TIRR) in Houston, TX, in the spinal cord injury (SCI) program. Since 2011, I have been engaged in basic and clinical SCI research within the Kentucky Spinal Cord Injury Research Center at the University of Louisville, developing neurophysiological and electrophysiological techniques for quantitative evaluation of spinal connectivity and volitional neuromuscular activation capacity after SCI. upon graduation in 2016, I moved to the pediatric Neurorecovery research lab of Dr, Andrea Behrman. I am interested in the development/refinement of 1) novel intervention strategies to promote improved recovery of neuromuscular function after SCI, and 2) sensitive and predictive physiological and clinical outcome measures, which are needed to identify underlying mechanisms of neuroplasticity thought to mediate functional recovery. Education:

Harding University BS 08/1999 05/2003 Exercise Science

UTSW medical center MPT 05/2003 05/2005 Physical Therapy

University of Louisville

University of Louisville MS PhD 01/2010 08/14 University of Louisville PhD 08/2014 12/2016 Anat. Sci. and Neurobiol

This author has no relevant disclosures.Mary Schmidt Read, PT, DPT, MSMagee Rehabilitation Hospital This author has no relevant disclosures.Candy Tefertiller, PT, DPT, NCSCraig Hospital This author has no relevant disclosures.elizabeth watson, PT, DPT, NCSMagee Rehabilitation Hospital This author has no relevant disclosures.Amanda Oakley, PT, DPT, NCSFrazier Rehab Institute This author has no relevant disclosures.Meghan Joyce, PT, DPT, NCSCraig Hospital This author has no relevant disclosures.Gail Forrest, PhDKessler Rehab Institute This author has no relevant disclosures.Buffy Wojceihowski, PT, DPTKessler Rehab Institute This author has no relevant disclosures.D. basso, Ed.D, PTThe Ohio State University This author has no relevant disclosures.Sue Ann Sisto, PT, MA, PhD, FACRMStony Brook University This author has no relevant disclosures.Susan Harkema, PhDUniversity of Louisville This author has no relevant disclosures.Andrea Behrman, PhD, PTUniversity of Louisville This author has no relevant disclosures.

54Parenting an adolescent with SCI: A case study on responsive parentingWednesday, May 02, 2018 09:30 AM - 10:30 AMLearning Objectives:Identify the potential importance of responsive parenting in SCI.

Participants:Taylor HTirr Memorial Hermann , Houston , TX, USHeather Taylor, PhDTirr Memorial Hermann Bio:Dr. Heather Taylor is the Director for Spinal Cord Injury and Disability Research (SCIDR) at TIRR Memorial Hermann. She is also the former Associate Director for Research for the Center for Research on Women with Disabilities in the department of Physical Medicine and Rehabilitation at Baylor College of Medicine. Dr. Taylor has focused her research on health, motor recovery and learning, and psychosocial functioning with a strong emphasis on women and children with SCI. She has published widely and presented nationally and internationally on research in the context of SCI. Dr. Taylor is the current founder and Chair for the American Congress of Rehabilitation Medicine’s SCI Interdisciplinary Special Interest Group Women’s Health Task Force (ACRM SCI-ISIG WHTF) focusing on the unique concerns of women’s health after SCI. She is also the current Chair for the American Spinal Injury Association’s (ASIA) Pediatric Committee sharing her mission to improve the lives of children with SCI. Dr. Taylor is the project director for the Texas Model Spinal Cord Injury System. Additionally, she is principal investigator on multiple projects and subcontracts collaborating nationally on motor recovery, health, and appropriate measures for adults and children with SCI. Education:Ohio University, Athens, Ohio BA 08/1992 Psychology

Ohio University, Athens, Ohio MS 06/1994 Human and Consumer Sciences

Ohio University, Athens, Ohio MED 06/1994 Counseling

University of Houston, Houston, TX PHD 05/2001 Counseling Psychology

University of Texas Medical Branch, Galveston, TX 07/2001 Clinical Neuropsychology and Rehabilitation Internship

Baylor College of Medicine, Houston, TX 09/2002 Rehabilitation Psychology Postdoctoral Training This author has no relevant disclosures.

55SCI-HIGH: Moving Best Practices with Indicator Implementation for Individuals with Spinal Cord Injury during Rehabilitation Care and in the CommunityWednesday, May 02, 2018 01:45 PM - 03:15 PMLearning Objectives:Upon completion of the course on “Developing and applying quality indicators among Individuals with Spinal Cord Injury (SCI) during rehabilitation care and in the community” attendees will be able to:

Describe and define the different types of quality indicators and the importance of linking to quality care – Bayley

Review the rehab care domain ranking process – Alavinia

Understand the role of Root Cause analysis in driving process improvements. And quality care - Flett

Design method for indicator development and implementation – Farahani

Discuss the SCI-High indicators and their role in accreditation standards and proposed quality indicators – Craven

Participants:1Craven C, 2Alavinia M, 2Flett H, 2Farahani F, 3Bayley M1University of Toronto , Toronto , Ontario, Canada; 2University Health Network , Toronto , Ontario, Canada; 3Division of Physiatry, University of Toronto , Toronto , Ontario, CanadaCatharine Craven, MD, FRCPUniversity of Toronto Bio:B. Catharine (Cathy) Craven, BA, MD, MSc, FRCPC is the Medical Lead of the Toronto Rehab Lyndhurst Centre Spinal Cord Rehabilitation Program and a Senior Scientist in the Neural Engineering and Therapeutics Team at Toronto Rehab’s Lyndhurst Centre within University Health Network. Dr. Craven is an Associate Professor in the Department of Medicine, Division of Physical Medicine and Rehabilitation, and Institutes of Rehabilitation Science and Health Policy Management and Evaluation at the University of Toronto, Canada. After completing a BA in Kinesiology at York University, Dr. Craven completed her Medical training and residency in Physical Medicine and Rehabilitation at McMaster University, and then completed training as a Clinical Scholar in Spinal Cord injury and a Master’s in Clinical Epidemiology at the University of Toronto. Dr. Craven has served as the Co- Chair of the 1st through 7th National SCI conference ( www.SCI2017.com ) in Canada, Scientific Officer for the Canadian Association of Physical Medicine and Rehabilitation, Chair of the Rick Hansen Institute CARE Committee, Inaugural Chair of the newly founded Canadian Spinal Cord Injury – Rehabilitation Association. Dr. Craven holds research funding from the Craig H. Nielsen Foundation, Canadian Institute of Health Research, Rick Hansen Institute, Ontario Neurotrauma Foundation and Physician

Services Inc. Dr. Craven was the 2017 CAPMR Award of Merit Recipient. Dr. Craven’s current research focuses on reducing Endocrine Metabolic disease (fracture, heart disease, and diabetes) risk after spinal cord injury and enhancing health services for patients with SCI in Canada by 2020 through leadership of the E-Scan Atlas (www.idapt.com/research/E-scan )and SCI-HIGH projects (https://sites.google.com/view/sci-high/home). Dr Craven has published over 125 papers on related topics. Education:B. Catharine (Cathy) Craven – Educational Summary

1984-1989 – York University – BA 1991-1994 – McMaster University – MD 1994-1998 - McMaster University – FRCP(c) Physical Medicine and Rehabilitation 1998-1999 – University of Toronto, Department of Medicine Clinical Scholar, Physiatry SCI 2003-2007 - University of Toronto – MSc Clinical Epidemiology This author has the following disclosures:

Research Support Consultant Other (see below)

Rick Hansen Institute, Chair of the Canadian Spinal Cord Injury - Rehabilitation Association , CIHR, Craig H. Neilsen Foundation, Physicians' Services Incorporated Foundation, Toronto Rehab Foundation, Ontario Neurotrauma Foundation, Toronto Rehab FoundationMohammad Alavinia, MD, PhDUniversity Health Network Bio:Mohammad Alavinia, MSc, MD, PhD has been working as a member of Neural Engineering and Therapeutics Team at Toronto Rehab’s Lyndhurst Centre within University Health Network since 2014. He graduated from Tehran Medical School as a family physician and subsequently completed MSc and PhD training in Clinical Epidemiology in the Erasmus-mc University in the Netherlands, where he studied workers’ health through application of the Work Ability Index (WAI). After graduation, he focused his research on communicable and non-communicable diseases and development of health quality indicators for Type II diabetes mellitus. Dr. Alavinia has served as an assistant professor of epidemiology at medical school, the director of the Program for Control and Prevention of Type-II Diabetes at Centers for Disease Control and Prevention at the Ministry of Health of Iran, and the director of the Vector-Borne Diseases Research Center, North Khorasan University of Medical Sciences. During his fellowship at Lyndhurst Centre, he participated in the design, implementation, and evaluation of care indicators for SCI rehabilitation locally and nationally (the SCI-HIGH project) (https://sites.google.com/view/sci-high/home) as well as contributes to quality improvement activities related to minimizing Urinary Tract Infections. Dr. Alavinia has published over 25 papers on various topics.Education:S. M. (Mohammad) Alavinia – Educational Summary

1985 – 1992 – Iran University of Medical Sciences – MD 1997 – 2000 – Tehran University of Medical Sciences – MPH

2004 – 2005 – Netherlands Institute for Health Sciences – MSc Clinical Epidemiology 2005- 2006 – Erasmus-mc University – DSc Clinical Epidemiology 2004 – 2008 – Erasmus-mc University – PhD Clinical Epidemiology

This author has the following disclosures: Research Support

Toronto Rehab Foundation, Rick Hansen InstituteHeather Flett, MSc, BScPTUniversity Health Network Bio:Heather Flett, BA, BScPT, MSc is the Advanced Practice Leader of the Toronto Rehab Lyndhurst Centre Spinal Cord Rehabilitation Program and a lecturer in the Department of Physical Therapy at the University of Toronto, Canada. Heather’s career in the field of spinal cord rehabilitation almost 20 years, first as a physical therapist in inpatient spinal cord rehabilitation and then for the last 11 years as Advanced Practice Leader, with a focus on the integration of research into practice. Heather’s graduate studies examined the relationship of sensorimotor function on walking outcomes following incomplete spinal cord injuries. Heather has led the implementation of numerous best practice initiatives within spinal cord rehabilitation. Most recently, Heather was a Toronto site co-lead for the SCI Knowledge Mobilization Network, a six site Canadian collaboration focusing on the implementation of best practices in the areas of pressure injuries and pain. Heather has been a co-investigator on numerous spinal cord rehabilitation studies in the areas of pressure injuries, walking, outcome measures, and falls. Heather has presented her work at several national and international conferences and has published over 20 papers and 2 book chapters in the area of spinal cord rehabilitation. Education:Heather Flett – Educational Summary

1990-1994 - University of Western Ontario – BA

1994-1998 - University of Toronto – BSc Physical Therapy

2003-2009 - University of Toronto – MSc Rehabilitation Science This author has the following disclosures:

Research SupportRick Hansen InstituteFarnoosh Farahani, BA, CCRPUniversity Health Network Bio:Farnoosh Farahani, HSBc, CCRP, is a working member of the Neural Engineering and Therapeutics Team at Toronto Rehab’s Lyndhurst Centre within University Health Network. Farnoosh has obtained an Honors Bachelor in Science from University of Toronto in 2004, specializing in human biology. During her undergraduate studies, Farnoosh participated in various independent research projects and developed a keen interest in clinical research. Since then, she has worked in several research settings including pharmaceutical, contract research organization, as well as acute and rehabilitation hospitals. Since December 2009, Farnoosh has

been working as a research coordinator under the supervision of Dr. Cathy Craven in the area of spinal cord injury rehabilitation. During her employment at Toronto Rehab, she has managed qualitative and quantitative research projects, national registries, participated in conferences and report out meetings, as well as collaborated with other acute and rehab sites across Canada. Her research interests include 1) improving the quality of rehabilitation care for people living with a spinal cord injury 2) implementation of best practices that improve patient outcomes 3) knowledge mobilization activities. Education:Farnoosh Farahani – Educational Summary

1999 - 2005 Honors Bachelor of Science, Human Biology Specialist, University of Toronto, Toronto, Canada 2015-Present Project Management, University of Toronto School of Continuing Education 2014- Present Certified Clinical Research Professional (CCRP), The Society of Clinical Research Associates (SOCRA) This author has no relevant disclosures.Mark Bayley, MD, FRCPCDivision of Physiatry, University of Toronto Bio:Mark Bayley, MD, FRCPC

Mark Bayley is currently Medical Director and Senior Scientist at the Brain and Spinal Cord Rehabilitation Program at Toronto Rehab. He is Professor and Saunderson Family Chair in Brain injury Research at the University of Toronto in the Division of Physical Medicine and Rehabilitation, Faculty of Medicine. Mark’s research focuses on understanding how to speed brain recovery through exercise, virtual reality, telerehabilitation and functional electrical stimulation. Importantly, he has explored novel implementation strategies to bridge the knowledge-practice gap by making best evidence available to clinicians through smartphone apps and Best Practices guidelines in stroke, concussion and Brain injury. His work has redesigned the stroke and brain injury rehabilitation systems in Canada. http://ihpme.utoronto.ca/faculty/mark-bayley/ Education:Mark Bayley – Educational Summary

Queens University at Kingston, Canada BA 05/1988 Chemistry

Queens University at Kingston, Canada MD 06/1988 Medicine

Division of Physiatry, University of Toronto FRCPC 09/19992 Physical Medicine and Rehabilitation This author has the following disclosures:

Research SupportCIHR, Canadian Spinal Cord Injury - Rehabilitation Association

56

Human Rights and Access to Technology by People with Spinal Cord InjuryWednesday, May 02, 2018 03:25 PM - 04:25 PMLearning Objectives:1. Identify the issues surrounding access to technology for an orphan population such as SCI. 2. Identify and articulate human rights that can enable people with SCI to access technology. 3. Discuss the responsibilities, risks and costs of constituents along the technology development path to improve access and availability to the end user. 4. Explore the advocacy roles of stakeholders and methods by which systemic change can occur. 5. Understand the need for people with SCI to advocate on their own behalf, and on behalf of peers.

Participants:1Bryden A, 1Gran B, 2Anderson K, 1Moynahan M1Case Western Reserve University , Cleveland , Ohio, USA; 2Miami Project to Cure Paralysis , Miami , FL, USAAnne Bryden, MA, OTR/LCase Western Reserve University Bio:Anne Bryden, MA, OTR/L is the Director of Clinical Trials and Research for the Institute for Functional Restoration (IFR) at Case Western Reserve University. The IFR is a non-profit organization with the mission of translating science and technological research interventions targeted toward spinal cord injury and other paralytic conditions into clinical programs to help people with these conditions. The IFR is closely affiliated with The Cleveland FES Center.

Anne received her Bachelor of Science in Occupational Therapy from Cleveland State University in 1991. She has a Master’s degree in Sociology and is currently a doctoral candidate in Sociology at Case Western Reserve University. Anne has over twenty years of experience specializing in upper extremity care of people with cervical spinal cord injury. Anne leads the functional assessment program for upper extremity neuroprosthetics and reconstructive surgeries at The Cleveland FES Center. Currently she is responsible for leading the multi-center pivotal clinical trial for the networked neuroprosthesis, the latest innovation developed at the Cleveland FES Center. Her research interests include upper extremity assessment, surgical interventions, outcomes measurement, and the social determinants of health and wellness in people with chronic physical disability. Additionally, she is exploring the experiences of navigating health and social resources following SCI through the lens of human rights, by measuring barriers and facilitators to obtaining services necessary for quality of life. She is also conducting research on the human rights knowledge base of health professionals and other stakeholders involved in the care of people with SCI.

Anne has authored and co-authored several peer-reviewed publications on the topic of spinal cord injury. She is the recipient of the 2015 Neilsen Foundation Allied Health Professional Research Award of the American Spinal Injury Association (ASIA). Currently Anne is the Chair of the Rehabilitation Standards Committee of ASIA and an active member of the Research Committee of the Academy of Spinal Cord Injury Professionals. Additional professional

memberships include The American Occupational Therapy Association, The American Sociological Association and the International Spinal Cord Society.Education:Cleveland State University B.S. 06/91 Occupational Therapy Cleveland, Ohio Case Western Reserve University M.A. 05/17 Sociology Cleveland, Ohio Case Western Reserve University Ph.D. est 2019 Sociology Cleveland, Ohio This author has no relevant disclosures.Brian Gran, PhD, JDCase Western Reserve University Bio:I am a sociologist and lawyer whose work concentrates on human rights and institutions that support and hinder their enforcement, with a particular interest in how rights can foster science and improve lives of individuals with disabilities. As a lawyer, I represented individuals who pursued disability claims with the U.S. Social Security Administration. As an academic, I am contributing to scholarship on research and methodological innovations useful to answering questions about rights, science, and disability. I have published in a variety of domains, including podcasts, and am pursuing innovations in disseminating research and knowledge about human rights and science. I am a nominee of the Andrew Carnegie Fellowship. With David Brunsma and Keri Iyall Smith, I edited The Handbook of Sociology and Human Rights. Under contract with Polity Press I am preparing the book, Sociology of Children’s Rights. I have enjoyed invitations to publish with The Annual Review of Law and Society and Problemy Wczesnej Edukacji, as well as to give lectures to COST Action IS1409 in Barcelona and the Social Science Korea Human Rights Forum in Seoul. I co-direct the inaugural International Survey of Human Rights. I am a co-founder of the ASA Human Rights section and I have served on the Steering Committee and Council of the Science and Human Rights Project of the American Association for the Advancement of Science. I am former President of the thematic group on Global Justice and Human Rights of the International Sociological Association and am the current editor of the journal, Societies Without Borders, the flagship journal of Sociologists Without Borders. I serve as a reviewer for various journals and organizations, including the U.S. National Science Foundation (NSF)

and the Fulbright Commission. I have enjoyed support from the NSF, the Swiss National Science Foundation, and was a Fulbright Scholar to Iceland. I am one of fourteen members of the U.S. National Conference of Lawyers and Scientists.Education:DePauw University, Greencastle, Indiana. B.A. 08/81-05/85 English Literature Indiana University, Bloomington, Indiana. J.D. 08/85-05/88 Law Northwestern University, Evanston, Illinois Ph.D. 09/90-07/97 Sociology Yale University, Robert Wood Johnson Scholar in Health Policy, New Haven, Connecticut 08/97-07/99 Health PolicyThis author has no relevant disclosures.Kimberly Anderson, PhDMiami Project to Cure Paralysis Bio:My research experience spans from cellular and molecular neuroscience in graduate school, to in vivo animal models of cervical spinal cord injury (SCI) and forelimb function as a post-doctoral fellow, to clinical studies as an Adjunct Assistant Professor at UC Irvine. I purposefully gained experience in those three very different avenues of research. I wanted to use my personal experience and knowledge gained from living with a spinal cord injury for 27 years combined with my detailed understanding of cellular, whole animal, and human research to make a unique difference in the lives of many people living with SCI. The opportunity to do so availed itself to me in 2009 and I joined the Miami Project as the Director of Education. In addition to continuing my outreach and education efforts, I have continued a research track. I was the PI conducting a multi-center clinical trial validating the Spinal Cord Independence Measure (SCIM III) in the US healthcare setting. I was recently the Chair of the NINDS SCI CDE Functional Outcomes Working Group. Several of my studies have focused on obtaining the perspective of people living with SCI on various aspects of research, including functional priorities, acceptable benefits and risks, preferences for neuroprosthetics, and exercise participation. One of my current projects focuses on identifying the facilitators and barriers to clinical trial participation from the SCI consumer perspective. I have significant experience with consumer-oriented research.Education:Texas A&M University, Galveston B.S.1990-1995 Marine Biology

Univ. of New Mexico Sch. of Med., Albuquerque Ph. D. 1996-2000 Biomedical Sciences

University of California, Irvine Post-doc 2000-2004 Spinal Cord Injury This author has no relevant disclosures.Megan Moynahan, MSCase Western Reserve University Bio:As the Executive Director of the Institute for Functional Restoration (IFR), I am accountable to

my organization’s mission: to restore function to people with paralysis by creating a sustainable commercialization model for neuromodulation devices. The IFR serves as a commercialization pathway for technologies developed at Case Western Reserve University that are intended for small (orphan) markets. A critical part of that mission is to advocate for a better commercialization ecosystem for the entire field of neuromodulation. Toward that end, I serve in an advocacy role with FDA, CMS, and industry partners to create the most favorable commercialization pathway for these technologies. I work with investigational teams to ready them for eventual commercial translation, including assisting with high-level regulatory strategies through the FDA process, developing partnerships with industry, and strategizing on evidentiary needs for reimbursement.

I come to my role as Executive Director for the Institute for Functional Restoration following a 17-year career at FDA’s Center for Devices and Radiological Health. In my last position at FDA, I served as Associate Director for Technology and Innovation, in which I was responsible for directing two of its most prominent programs, the White House-sponsored Entrepreneurs in Residence program and the Innovation Pathway program, a streamlined regulatory program for innovative medical devices.

My regulatory background is strongest on the pre-market side for medical devices, having worked six years as a front-line reviewer at FDA, followed by six years as supervisor for the Pacing and Defibrillators branch at FDA. In those two roles, I was responsible for the premarket reviews of over 6,000 FDA applications from hundreds of companies. Those applications included requests to begin clinical studies (Investigational Device Exemptions, or IDEs), and marketing applications for both lower risk devices (510(k)s) and high-risk devices (Premarket Applications, or PMAs). In addition, I have extensive experience navigating the regulatory framework on the post-market side of FDA. For example, I worked on medical device adverse event reporting, product recalls, inspections, bioresearch monitoring of clinical trials, and risk communication efforts. From these experiences, I was able to create novel programs and business processes inside the FDA to coordinate these disparate functions into a whole, most notably serving as chief architect of the Signal Management program.Education:Johns Hopkins University BS 1986 Biomedical Engineering

Case Western Reserve University MS 1990 Biomedical Engineering This author has no relevant disclosures.

57Training on the Administration, Scoring and Interpretation of the Spinal Cord Injury-Functional Index and the Pediatric Spinal Cord Injury Activity MeasureWednesday, May 02, 2018 01:45 PM - 03:15 PMLearning Objectives:1.) Describe CAT functionality and understand how CATs provide customized assessments. 2.) Explain the conceptual framework underlying the SCI-FI and PEDI-SCI AM assessments and

list the domains assessed by each. 3.) Given clinical vignettes, administer a CAT assessment and explain how to interpret the scores and use them to develop treatment goals.

Participants:1Mulcahey M, 2Slavin M, 1Thielen C1Thomas Jefferson University , Philadelphia , PA, United states; 2Boston University , Boston , MA, USAMJ Mulcahey, PhD, OTR\LThomas Jefferson University Bio:MJ Mulcahey is Professor in the Department of Occupational Therapy, Jefferson College of Health Professions, Thomas Jefferson University, Philadelphia, PA, USA. She has focused her clinical practice in rehabilitation of children and youth with spinal cord injuries (SCI), and other chronic physical conditions. She worked as an occupational therapy clinician and researcher, and served as the Director of Rehabilitation and Clinical Research at the Shriners Hospitals for Children, Philadelphia, USA for 26 years, and is now a member of their scientific staff. Her research has focused on development and validation of performance and patient reported outcome measures for children with SCI, cerebral palsy, spine impairments, and brachial plexus birth palsy, and on the outcomes of intervention for upper limb function in youth with SCI. She has published over 150 peer-review manuscripts, and has authored 15 chapters on pediatric SCI, SCI upper extremity management, and occupational therapy for children with SCI. She is also co-editor of two textbooks on pediatric SCI, associate editor of Topics in Spinal Cord Injury Rehabilitation, and immediate past President of the American Spinal Injury Association. Education:BS Special Education MS Occupational Therapy PhD Education This author has the following disclosures:

Research Support Other (see below)

Dr. Mulcahey receives funding from the Criag H. Neilsen Foundation, Shriners Hospitals for Children, NINDS and Rick Hansen Institute.

Dr. Mulcahey receives compensation for her role as associate editor of Topics in Spinal Cord Rehabilitation.

Dr. Mulcahey is the immediate Past President of ASIA, Vice President of the Pediatric Spine Foundation and Chair of the Steel Assembly. Mary Slavin, PhD, PTBoston University Bio:Mary Slavin is a research associate in the Department of Health Law, Policy and Management at Boston University School of Public Health. She served as the Director of Education and

Dissemination at the Health and Disability Research Institute, located at the Boston University School of Public Health, Boston MA, USA. Dr. Slavin is a physical therapist who has worked in SCI as a clinician, educator and researcher. Her research has focused on development of sophisticated rehabilitation outcome measures. She was involved in the development and testing of the Spinal Cord Injury Function Index (SCI-FI), a new patient-reported measure for adults with SCI. She contributed to the development and testing of the PEDI-SCI. Education:Clark University Experimental Psychology, PhD

Boston University Sargent College of Health and Rehabilitation Sciences Physical Therapy-Teaching Specialization, MS

Northeastern University Physical Therapy, BS This author has the following disclosures:

Other (see below)

Dr. Slavin serves on the Board for the Rehabilitation Taxonomy DRRP, and am only compensated for travel expenses for Board meetings. Christina Thielen, MS PTThomas Jefferson University Bio:Christina is a research coordinator of several multi-center studies and is responsible for overall coordination of study implementation. She is trained as a Physical Therapist and has expertise in pediatric SCI. She is adjunct faculty in the Dept. of Physical Therapy, Thomas Jefferson University, Philadelphia PA. Education:BS Kinesiology MS Physical TherapyThis author has no relevant disclosures.

58The importance of tissue perfusion in acute and chronic spinal cord injury: New Findings in Animal and Human ModelsWednesday, May 02, 2018 01:45 PM - 03:15 PMLearning Objectives:Discuss how spinal cord perfusion pressure (SCPP) can predict neurologic recovery.

Appreciate the value of animal models of spinal cord injury (SCI) in advancing the field.

Explained the benefits of detecting and addressing blood pressure dysregulation in persons with SCI

Participants:1Krisa L, 2Jones L, 3Bloom O, 4Papadopoulos M, 5West C, 6Guest J, 7Wecht J1Thomas Jefferson University , Philadelphia , Pennsylvan, United states; 2Craig H. Neilsen Foundation , Encino , California, United states; 3The Feinstein Institute for Medical Research , Manhasset , NY, USA; 4St. George’s University Hospitals , Wandsworth , , England; 5Icord (International Collaboration on Repair Discoveries) , Vancouver , BC, Canada; 6The Miami Project to Cure Paralysis , Miami , FL, USA; 7James J. Peters Va Medical Center and the Mount Sinai School of Medicine , Bronx , NY, USALaura Krisa, PhDThomas Jefferson University Bio:Laura Krisa, PhD is an Assistant Professor in the departments of Physical and Occupational therapy at Thomas Jefferson University. After receiving a bachelors degree in biology she earned her PhD in Neuroscience from Drexel University College of Medicine. Laura’s research focus is using advanced imaging techniques, including functional Magnetic Resonance Imaging (fMRI) and Diffusion Tensor Imaging (DTI) as potential biomarkers in persons with spinal cord injury. Her recent work has indicated positive findings in using these techniques in conjunction with the clinical exam to further define injury location and severity. Education:Millersville University, Milllersville, PA BS in Biology 2000-2004

Drexel University College of Medicine PhD in Neuroscience 2005-2010This author has no relevant disclosures.Linda Jones, PTCraig H. Neilsen Foundation Bio:Linda Jones is a Program Officer for the Spinal Cord Injury Research on the Translational Spectrum (SCIRTS) program. She co-manages the funding portfolio that spans mechanistic, translational and early clinical research aimed at improving recovery from spinal cord injury. With over 20 years of experience, Linda has applied her clinical expertise, serving as a consultant and staff member in a number of pharmaceutical, biotechnology, exoskeleton and healthcare settings. She worked at Geron Corporation from 2006-2011, preparing and managing the first clinical trial in the United States utilizing cells derived from human embryonic stem cells, in a Phase I study in patients with neurologically complete, sub-acute spinal cord injury. Prior to this, she worked with Proneuron Biotechnologies, the sponsor of the first Phase 1 cell-based study (autologous macrophage injection) in spinal cord injury, and subsequently managed the Phase II trial. Linda also worked at Denver Health Medical Center for 12 years, with a focus on physical therapy interventions in the intensive care unit. As a result of this background, Linda has experience reviewing preclinical data and integrating necessary components of these findings into the clinical trial/protocol, assessing the feasibility of trial implementation, developing the operational infrastructure to execute trials and addressing regulatory challenges. Her focus has been on applying lessons from an operational perspective that are learned in clinical trials and addressing gaps in outcome measures used in such trials. Publications have focused on results and “lessons learned” from the Proneuron trial as well as

the natural history of recovery (based on data from the European Multicenter Study about Spinal Cord Injury – EMSCI) and outcome measures in spinal cord injury. Linda has also participated in publications on updates to and challenging cases based on the International Standards for the Neurological Classification of Spinal Cord Injury. Linda has been a guest lecturer at the University of Colorado, as well as a guest lecturer, affiliate faculty and instructor at Regis University, with a focus on complex systems, critical care, and neuroscience. She currently sits on several committees within professional organizations addressing spinal cord injury. Linda completed her Advanced Master’s Degree in neurological physical therapy from Samuel Merritt College and her undergraduate degrees in kinesiology and physical therapy from the University of Colorado. She is currently enrolled in a Doctoral Program at the University of Colorado in Clinical Science, in the Clinical Investigation track. Education:

PhD student, Clinical Sciences, Clinical Investigation track, University of Colorado, Denver, Colorado 2014- presentThis author has no relevant disclosures.Ona Bloom, PhDThe Feinstein Institute for Medical Research Bio:Dr. Ona Bloom is director of The Laboratory of Neuroimmunology and associate professor at the Feinstein Institute for Medical Research. She is jointly appointed as associate professor of Physical Medicine & Rehabilitation and of Molecular Medicine at the Donald and Barbara Zucker School of Medicine at Hofstra/Northwell. Dr. Bloom also serves as the director of research for the Department of Physical Medicine and Rehabilitation.

Prior to joining Northwell Health, Dr. Bloom performed her postdoctoral studies and served as an associate research scientist in the Departments of Cell Biology and Immunology at the Yale University School of Medicine. Her studies at Yale focused on understanding how immune cells communicate with each other. Dr. Bloom received her PhD from The Rockefeller University, where she studied molecular and cellular neuroscience in the laboratory of Professor Paul Greengard. Her PhD studies were focused on understanding the molecular anatomy of synapses, the points of communication between nerve cells.Education:Barnard College Degree: BA Field of Study: History

The Rockefeller University Degree: PhD Field of Study: Molecular and Cellular Neuroscience

Yale University School of Medicine Degree: Postdoc Field of Study: Cell Biology/Immunology

This author has no relevant disclosures.Marios Papadopoulos, MD,FRCS(SN)St. George’s University Hospitals Bio:Marios Papadopoulos is a Professor of Neurosurgery at the University of London (St. George’s) (https://www.stgeorges.nhs.uk/people/marios-papadopoulos/). He was educated at the Universities of Cambridge and Oxford and completed his neurosurgery training in London and San Francisco. His clinical interests are complex spinal surgery and vascular neurosurgery. His research interests are aquaporin water channels and their roles in the CNS. He developed a novel technique to monitor intraspinal pressure and spinal cord perfusion pressure in patients with severe spinal cord injury in the neurointensive care unit. This is analogous to monitoring intracranial pressure and cerebral perfusion pressure in patients with severe brain injury. He showed that, after spinal cord injury, the swollen cord becomes compressed against the surrounding dura. Therefore, in addition to open reduction and laminectomy, he proposed expansion duroplasty to effectively decompress the injured spinal cord. Education:University of Cambridge, U.K. BA 1990 Medical Sciences University of Oxford, U.K. BM BCh 1993 Clinical Medicine University of Cambridge, U.K. MD 1997 Neuroscience Royal College of Surgeons, U.K. FRCS 1998 Surgery Royal College of Surgeons, U.K. FRCS (SN) 2002 Neurosurgery

This author has the following disclosures: Research Support

Christopher West, PhDIcord (International Collaboration on Repair Discoveries) Bio:Dr. West is a translational research scientist who investigates the autonomic and cardiorespiratory consequences of SCI. His research traverses the discovery science-clinical spectrum: at the discovery science level, he investigates the mechanisms that underpin cardiac and vascular adaptations to exercise, and at the clinical level, he works with Paralympic athletes

to investigate the limitations to exercise performance, and more recently the relationship between autonomic completeness of injury, sporting classification and cardiovascular function. “While we know that exercise is beneficial for people with spinal cord injury, we are still far from understanding the optimum mode, intensity and duration of exercise that is best,” says Dr. West. “Equally we still do not truly understand if and how exercise exerts a beneficial cardio-protective effect in the SCI population.”Education:B.Sc. (Sport & Exercise Science) [University of Essex] M.Sc. (Sport & Exercise Science – Human Performance) [Brunel University] Ph.D. (Sport & Exercise Science – Spinal Cord Injury) [Brunel University] Assistant Professor, School of Kinesiology, Faculty of Education, University of British Columbia

This author has the following disclosures: Research Support

James Guest, M.D., Ph.D., F.A.C.S., F.R.C.S. (C)The Miami Project to Cure Paralysis Bio:Dr. Guest’s extensive contributions to the field of spinal cord injury, both in terms of medical practice and research, span over two decades. He’s held numerous hospital appointments such as attending neurosurgeon at the Barrow Neurological Institute, West Palm Beach VA Medical Center, the University of Miami Hospital, and Chief of Spinal Neurosurgery at Miami Veteran’s Medical Center. He’s given more than 25 invited lectures domestically and internationally and has authored over 75 peer-reviewed publications, including articles, book chapters, and abstracts in the areas of cellular therapy for spinal cord injury, biology of neuroglia, and mechanisms of secondary injury. Dr. Guest has been active in research design for human clinical trials, participating as a Principal Investigator for the North American Clinical Trials Network (NACTN) for the Treatment of Spinal Cord Injury.

Dr. Guest earned a Bachelor of Arts in Economics and Political Science, a Bachelor of Science in Chemistry and Biology, and a Medical Degree from the University of Alberta, Edmonton in Canada. He also earned a Ph.D. from the University of Miami, Department of Neuroscience in Miami, FL. His thesis was titled “The potential for human Schwann cell grafts to influence spinal cord regeneration in the nude rat.” Dr. Guest completed his residency in the Division of Neurosurgery at the University of British Columbia in Vancouver, Canada and a fellowship in Spinal Surgery at the Barrow Neurologic Institute in Phoenix, Arizona.Education:University of Alberta, Edmonton, Canada. B.A., Economics and Political Science, 9/79 – 5/83 University of Alberta, Edmonton, Canada. B.Sc., Chemistry and Biology (magna cum laude), 9/83 – 5/85 University of Alberta School of Medicine, Edmonton, Canada. M.D. (magna cum laude with honors in research), 8/85 – 6/89 Thesis title: “The production and characterization of monoclonal antibodies to clinically relevant surface antigens of Chlamydia Trachomatis.” Supervisor: Wanda Wenman, MD.

University of Miami, Department of Neuroscience, Miami, FL. Ph.D., Neuroscience, 7/93 – 9/96. Thesis title: “The potential for human Schwann cell grafts to influence spinal cord 2 of 18 regeneration in the nude rat.”Thesis advisor: R. P. Bunge, Ph.D. US Copyright Registration: TX4-996-628 Internship: St. Paul’s Hospital, Vancouver, British Columbia, Canada. 7/89 – 6/90 Residency: Department of Neurosurgery, University of British Columbia, Canada. 7/90 – 6/98 Rotation: Brain Institute - University of Zurich, Zurich, Switzerland. Supervisor: Dr. ME. Schwab, PhD. Myelin-associated inhibition of neuronal sprouting and regeneration in the adult CNS. 7/94- 09/94This author has the following disclosures:

Research SupportJill Wecht, EdDJames J. Peters Va Medical Center and the Mount Sinai School of Medicine Bio:ill M Wecht, EdD, is a Professor of Medicine and Rehabilitation Medicine at ISMMS and has been studying the effects of de-centralized autonomic cardiovascular control on heart rate and blood pressure in persons with SCI since receiving her Doctorate of Education from Columbia University in 1999. Dr. Wecht is the Program Director of the Cardiovascular Autonomic Program within the National Center for the Medical Consequences of SCI at the JJPVAMC and is the co-chair of the International Consortium of Clinicians and Scientists working to develop International Standards to Document the Remaining Autonomic Function following SCI. Dr. Wecht is currently funded by the Rehabilitation Research & Development Service of the VA, the Craig H. Neilsen Foundation, the New Jersey Commission for Spinal Cord Research and by the National Institute for Disability and Independent Living Rehabilitation Research to study the impact of blood pressure dysregulation on cognitive health and quality of life and determine the effects of increasing blood pressure with anti-hypotensive agents on these outcomes in persons with chronic SCI.Education:INSTITUTION AND LOCATION DEGREE (if applicable)

Completion Date MM/YYYY

FIELD OF STUDY

Millersville University, Millersville, PA B.S. 05/04

Biology

Drexel University, Philadelphia, PA Ph.D. 05/10 Neuroscience

Shriners Hospitals for Children, Philadelphia, PA Post-Doctoral Fellowship 03/13 Clinical Neuroscience This author has the following disclosures:

Research Support

59Assessment and Treatment of Neuropathic Pain after Spinal Cord Injury from Bench to BedsideWednesday, May 02, 2018 01:45 PM - 03:15 PMLearning Objectives:On completion of this symposium participants will be able to: (1) Evaluate neuropathic pain in the clinic (2) Appreciate that there may be different neuropathic pain phenotypes that may reflect different mechanisms of neuropathic pain (3) Appreciate both the prospects and the limitations of translational research with respect to neuropathic pain treatment (4) Use the evidence based CanPain CPG recommendations to guide treatment of neuropathic pain

Participants:1Widerstrom-Noga E, 2Loh E, 3Weidner N, 4Bryce T1University of Miami Miller School of Medicine. , Miami , FL, USA; 2University of Western Ontario , London , Ontario, CA; 3Heidelberg University Hospital , Heidelberg , Germany, Germany; 4Icahn School of Medicine at Mount Sinai , New York , NY, USAEva Widerstrom-Noga, DDS, PhDUniversity of Miami Miller School of Medicine. Bio:Dr. Eva Widerstrӧm-Noga is a Professor of Neurological Surgery and Rehabilitation Medicine and the Principal Investigator of the Clinical Pain Research Laboratory of The Miami Project to Cure Paralysis. Her expertise is in cross-disciplinary pain research (pain physiology and pain psychology) in neurotrauma populations (spinal cord injury and traumatic brain injuries). She has performed human pain research for more than 24 years and in the field of SCI for over 20

years. Dr. Widerstrӧm-Noga has adapted outcome measures used to classify and assess pain in other chronic pain populations to people with SCI. She has published over 60 peer reviewed journal articles and written eight book chapters on pain and pain assessment. Her present research program is interdisciplinary and involves both qualitative and quantitative pain methodologies including quantitative sensory testing and MR spectroscopic brain imaging. Education:University of Gothenburg, Gothenburg, Sweden D.D.S. 1986 Dental Surgery University of Gothenburg, Gothenburg, Sweden Ph.D. 1993 Pain Physiology This author has the following disclosures:

Research Support Other (see below)

Employer: The Miami Project to Cure Paralysis, University of Miami Miller School of Medicine

Research support: DoD, NIDILRR, NICHDEldon Loh, MDUniversity of Western Ontario Bio:Dr. Eldon Loh (MD, FRCPC) completed undergraduate studies at the University of Toronto in 2001, and medical school at Western University in 2005. He completed residency training in Physical Medicine and Rehabilitation at the University of Alberta in 2010 and a clinical fellowship in interventional pain management at HealthPointe Medical Centre in 2011. He is currently an assistant professor in the department of Physical Medicine and Rehabilitation at Western University, Schulich School of Medicine and Dentistry, and consultant physiatrist at Parkwood Institute and the St. Joseph’s Health Centre Pain Clinic in London, Canada. His clinical and research interests include interventional pain management and chronic pain after spinal cord injury. He is chair of the panel that developed the Canadian Best Practice Guidelines for Neuropathic Pain after spinal cord injury (the CanPainSCI guidelines). He is also chair of the National Summit for Neuropathic Pain after SCI, which is providing guidance to ONF and RHI on improving neuropathic pain management after SCI.Education:1997-2001 Hon. B. Sc. University of Toronto (Toronto ON, Canada) – Human Biology, Philosophy (St. Michael’s College)

2001-2005 M.D. University of Western Ontario (London ON, Canada)

2005-2010 University of Alberta (Edmonton AB, Canada), PMR Residency

2010-2011 HealthPointe Medical Centre (Edmonton AB, Canada) This author has the following disclosures:

Research Support Other (see below)

Employer: University of Western Ontario; Lawson Health Research InstituteNorbert Weidner, MDHeidelberg University Hospital

Bio:Prof. Dr. Weidner, a board certified neurologist, is medical director and head of the Spinal Cord Injury Center at Heidelberg University Hospital since 2009. He oversees both, the comprehensive care for acutely and chronically spinal cord injured individuals as well as all research activities aiming for neuroregeneration and neurorehabilitation in spinal cord injury. He received his medical degree at the University of Wuerzburg in 1995. He completed his residency at the Neurology Departments at Würzburg and Regensburg University Hospital and the Neuropathology department at Heidelberg University Hospital to become a board certified neurologist in 2004. A three-year-long postdoctoral fellowship at the Department of Neurosciences, Center for Neural Repair, University of California, San Diego (1996-1999) shaped his research focus towards regenerative therapies following traumatic spinal cord injury. Accordingly, he successfully finished his habilitation entitled “Regenerative strategies for axonal repair in the injured peripheral and central nervous system” in 2005 at Regensburg University Hospital. He is author on more than 80 research papers and is the editor of recent textbooks focusing on repair strategies for the injured spinal cord and neurological aspects of spinal cord injury. He is member of the German Speaking Society for Paraplegia (DMGP) Germany Societies for Neurology (DGN) and Neuroscience (NWG), Society for Neuroscience (SFN) and the International Spinal Cord Society (ISCOS). He currently coordinates all clinical guideline activities at the DMGP. He received several spinal cord injury related research awards. He was principal investigator in a phase I anti-Nogo trial and is currently running a subsequent multi-center phase II trial besides several clinical trials investigating neurorehabilitative interventions.Education:1986 – 1993 MD, Medicine, University of Würzburg, Germany This author has the following disclosures:

Research Support Other (see below)

Employer: Heidelberg University Hospital Thomas Bryce, MDIcahn School of Medicine at Mount Sinai Bio:Dr. Thomas Bryce came to The Mount Sinai Medical Center in 1997 and has served as Medical Director of the Spinal Cord Injury Program since 2001 and as Medical Director of Rehabilitation Ambulatory Services since 2008. He received his undergraduate degree from Johns Hopkins University and his medical degree from Albany Medical College. He received specialty training in Rehabilitation Medicine at Thomas Jefferson University Hospital. Dr. Bryce is board certified in Physical Medicine and Rehabilitation and has sub-specialty certification in both Pain Medicine and Spinal Cord Injury Medicine. Dr. Bryce is involved with research related to spinal cord injury especially as it relates to the assessment of pain after spinal injury and the use of robotic exoskeletons to facilitate walking. He has authored numerous chapters and scientific articles on spinal cord injury. Dr. Bryce has been appointed by Governor Cuomo to the New York State Spinal Cord Research Board. Dr. Bryce is on the steering committee of the Consortium for Spinal Cord Medicine, a consortium of national organizations which publishes clinical guidelines related to the care of individuals with spinal cord injury. He has been a research grant reviewer for the Department of Defense, the European Science Foundation, and the Craig H. Neilsen Foundation.

Education:1985 – 1989 Johns Hopkins University BSE 1989 – 1993 Albany Medical College MD 1993 – 1994 Albany Medical Center Hospital Medicine 1994 – 1997 Sidney Kimmel Medical College PMR

This author has the following disclosures: Research Support Other (see below)

Research support: NIDILRR, Craig H. Neilsen Foundation Employer: Icahn School of Medicine at Mount Sinai

60Endocrine Metabolic Disease Risk - Moving from Concept to Clinical Trial ApplicationWednesday, May 02, 2018 03:25 PM - 04:25 PMLearning Objectives:On completion of this symposium participants will be able to: 1) Describe endocrine metabolic disease (EMD) risk and share clinical definitions for low bone mass, sarcopenia, obesity and sarcopenic obesity. 2) Understand the application of current cardiometabolic disease guidelines for dyslipidemia in the SCI population. 3) Gain insight into clinical trial participants frame of reference. 4) Review the RoBaCO trial methodology.

Participants:1Craven B, 2Nash M, 2Anderson-Erisman K1Toronto Rehabilitation Institute-Uhn , Toronto , Ontario, Canada; 2University of Miami Miller School of Medicine , Miami , Florida, United statesB. Catharine Craven, MDToronto Rehabilitation Institute-Uhn Bio:B. Catharine (Cathy) Craven, BA, MD, MSc, FRCPC is the Medical Lead of the Toronto Rehab Lyndhurst Centre Spinal Cord Rehabilitation Program and a Senior Scientist in the Neural Engineering and Therapeutics Team at Toronto Rehab’s Lyndhurst Centre within University Health Network. Dr. Craven is an Associate Professor in the Department of Medicine, Division of Physical Medicine and Rehabilitation, and Institutes of Rehabilitation Science and Health Policy Management and Evaluation at the University of Toronto, Canada. After completing a BA in Kinesiology at York University, Dr. Craven completed her Medical training and residency in Physical Medicine and Rehabilitation at McMaster University, and then completed training as a Clinical Scholar in Spinal Cord injury and a Master’s in Clinical Epidemiology at the University of Toronto. Dr. Craven has served as the Co- Chair of the 1st through 7th National SCI conference ( www.SCI2017.com ) in Canada, Scientific Officer for the Canadian Association of Physical Medicine and Rehabilitation, Chair of the Rick Hansen Institute CARE Committee, Inaugural Chair of the newly founded Canadian Spinal Cord Injury – Rehabilitation Association. Dr. Craven holds research funding from the Craig H. Nielsen Foundation, Canadian Institute of

Health Research, Rick Hansen Institute, Ontario Neurotrauma Foundation and Physician Services Inc. Dr Craven was the 2017 CAPMR Award of Merit Recipient. Dr Craven’s current research focuses on reducing Endocrine Metabolic disease (fracture, heart disease, and diabetes) risk after spinal cord injury and enhancing health services for patients with SCI in Canada by 2020 through leadership of the E-Scan Atlas (www.idapt.com/research/E-scan )and SCI-HIGH projects (https://sites.google.com/view/sci-high/home). Dr Craven has published over 125 papers on related topics. Education:1984-1989 – York University – BA 1991-1994 – McMaster University – MD 1994-1998 - McMaster University – FRCP(c) Physical Medicine and Rehabilitation 1998-1999 – University of Toronto, Department of Medicine Clinical Scholar, Physiatry SCI 2003-2007 - University of Toronto – MSc Clinical Epidemiology This author has the following disclosures:

Research SupportResearch Grant: Craig H Neilsen Foundation (#350642).Mark Nash, PhDUniversity of Miami Miller School of Medicine Bio:Mark S. Nash, Ph.D., FACSM is a tenured Professor of Neurological Surgery and Physical Medicine & Rehabilitation at the University of Miami School of Medicine, Principal Investigator of the Applied Physiology Research Laboratory for the Miami Project to Cure Paralysis, and Director of Research in Physical Medicine & Rehabilitation. He is a Fellow of the American College of Sports Medicine. Dr. Nash has primary interests in assessment/treatment of cardiometabolic disease risks after SCI. He has published more than 100 peer-review articles, scholarly monographs, and book chapters on these themes and related topics within rehabilitation physiology.

Dr. Nash has served on panels and research advisory boards for the NIH, CDC, and NIDILRR. He is currently an Editorial Board Member for Topics in SCI Rehabilitation, Chair of the ASIA Research & Awards Committee, and Chair of the PVA Consortium for Spinal Cord Medicine Guideline Panel on Cardiometabolic Disorders. Dr. Nash is PI for a DoD multi-center trial examining diabetes prevention after SCI through lifestyle intervention, and Co-PI on a DoD grant examining sleep disorders and cognitive dysfunction after SCI. Dr. Nash was PI for the NIDRR-funded multicenter trial examining Niaspan in Tetraplegia, for which he received the 2012 ASIA David Apple award. He is Co-Director of the NIDILRR South Florida SCI Model System, and PI for a recently awarded multi-center NIDILRR Disability Rehabilitation Research Project examining lifestyle intervention on cardiometabolic risks in stakeholders with SCI and their caregivers. Education:1976 University of Toledo- B.S. Biology 1980 University of Toledo- M.S. Human Physiology 1984 University of Toledo and Medical College of Ohio at Toledo- Ph.D. Applied Physiology and Clinical Anatomy This author has the following disclosures:

Research SupportResearch Grant: Craig H Neilsen Foundation (#350642).Kim Anderson-Erisman, PhDUniversity of Miami Miller School of Medicine Bio:Dr. Anderson-Erisman is a Research Professor and the Director of Education for The Miami Project to Cure Paralysis at the University of Miami Miller School of Medicine. Her research has focused on translational investigations and bridging the gap between basic science, clinical science, and the public community living with spinal cord injury (SCI). Her training spans the spectrum of SCI research, from cellular and molecular studies, to whole animal and behavioral studies, to human clinical research. She has conducted a multi-center clinical study evaluating the reliability and validity of the Spinal Cord Independence Measure in the US healthcare setting. Several of her studies have focused on obtaining the perspective of people living with SCI on various aspects of research, including functional priorities, acceptable benefits and risks, preferences for neuroprosthetics, and exercise participation. Her current projects focus on 1) aging related changes in bladder health after SCI, 2) determining the minimum amount of exercise and locomotor training required for clinical trials targeting chronic SCI, and 3) identifying the facilitators and barriers to clinical trial participation from the SCI consumer perspective. In addition to pursuing her own research regarding chronic injury, she is part of the leadership team running the Schwann cell transplantation clinical trials at the University of Miami.Education:1990-1995 Texas A&M University, Galveston- B.S. Marine Biology

1996-2000 Univ. of New Mexico Sch. of Med., Albuquerque- Ph. D. Biomedical Sciences

2000-2004 University of California, Irvine- Post-doc Spinal Cord Injury This author has the following disclosures:

Research SupportResearch Grant: Craig H Neilsen Foundation (#350642).

61Pediatric Spinal Cord Injury: Quality of Life Enhancement Through Learning to Eat and Speak AgainWednesday, May 02, 2018 03:25 PM - 04:25 PMLearning Objectives:1. Participants will be able to discuss the role of SLP in dysphagia and voice management after SCI. 2. Participants will be able to appreciate the impact of SCI on QOL of patient and parent. 3. Participants will be able to identify physiologic changes specific to SCI through use of video analysis of instrumental assessment(s) and therapy sessions utilizing equipment to enhance biomechanics.

Participants:

Maldonado K, Peck KChildren's Hospital Los Angeles , Los Angeles , California, United states of americaKayla Maldonado, MS, CCC-SLP, CBISChildren's Hospital Los Angeles Bio:Spanish-English Bilingual Pediatric Speech-Language Pathologist (SLP); also proficient in American Sign Language. Recognized as a Certified Brain Injury Specialist. Member of ASHA, American Spinal Injury Association (ASIA), and ASIA Pediatric Committee, which focuses on issues regarding pediatric Spinal Cord Injury (SCI). Specializes in the care of pediatric patients from NICCU through adulthood. Clinical interests include respiration, dysphagia, cognition and speech/language impairments following SCI, brain injury, cancer, prematurity, and prolonged hospitalization in the acute care setting.Education:Master of Science Degree, Gallaudet University Speech-Language Pathology 2010-2012

Bachelor of Arts Degree, University of California, Los Angeles (UCLA) Linguistics; Psychology

2008-2010This author has no relevant disclosures.Katy Peck, M.A., CCC-SLP, CBIS, CLC, BCS-SChildren's Hospital Los Angeles Bio:Pediatric Speech-Language Pathologist (SLP) recognized as a Board Certified Specialist in Swallowing, Certified Brain Injury Specialist, and Lactation Counselor with eighteen years of experience. Guest speaker for local and state conferences, national symposiums, and internationally broadcasted webinars. Authored published manuscripts on tracheostomy and dysphagia. Lead SLP responsible for training staff in instrumental assessments and care for patients with dysphagia complicated by prematurity, cardiorespiratory implications, neurologic impairment, spinal cord injury, and gastrointestinal implications in acute care.Education:Master of Arts Degree, Eastern Michigan University Speech and Language Pathology

Bachelor of Arts Degree, Michigan State University Audiology and Speech Sciences

Postgraduate Credential, California State University Physical and Health Impairments- Pending This author has the following disclosures:

ConsultantMs. Peck is a consultant for Passy-Muir Speaking Valve.

62

β2-adrenoreceptor-mediated mitochondrial biogenesis for the treatment of spinal cord injuryWednesday, May 02, 2018 03:25 PM - 04:25 PMLearning Objectives:Assess the therapeutic efficacy of β2-adrenoreceptor-mediated mitochondrial biogenesis as a potential therapeutic for the treatment of SCI using the FDA approved agonist formoterol.

Participants:1Scholpa N, 2Narang A, 2Wang W, 2Corum D, 2Tomlinson S, 1Schnellmann R1University of Arizona , Tucson , AZ, United states; 2Medical University of South Carolina , Charleston , SC, United statesNatalie Scholpa, PhDUniversity of Arizona Bio:Natalie E. Scholpa, PhD, is a Postdoctoral Scholar in the Department of Pharmacology and Toxicology at the University of Arizona in the lab of Rick G. Schnellmann, PhD, Dean of Pharmacy. After receiving her Bachelor's in biochemistry, with a minor in psychology, from the Georgia Institute of Technology in 2011, she earned her Doctoral degree in Toxicology with a focus on addiction-based neuroscience from the University of Georgia in 2015. Natalie chose to continue in the neuroscience field during her Postdoctoral career, focusing on mitochondrial-based therapeutics for the treatment of various neuropathologies, including spinal cord injury and Parkinson's disease. She has presented her work at multiple national and international conferences, and has won several awards for scientific merit and presentation skills. Natalie currently studies the therapeutic efficacy of pharmacological induction of mitochondrial biogenesis following spinal cord injury on functional recovery in vivo.Education:Georgia Institute of Technology (Atlanta, GA), BS 2007-2011 Biochemistry, Psychology Minor University of Georgia (Athens, GA) PhD 2011-2015 Toxicology Medical University of South Carolina (Charleston, SC), Postdoctoral scholar under Rick G. Schnellmann, PhD 2015-2016 University of Arizona (Tucson, AZ), Postdoctoral scholar under Rick G. Schnellmann, PhD 2016-PresentThis author has no relevant disclosures.Aarti Narang, PhDMedical University of South Carolina This author has no relevant disclosures.Wenxue Wang, Medical University of South Carolina This author has no relevant disclosures.Daniel Corum, Medical University of South Carolina This author has no relevant disclosures.Stephen Tomlinson, Medical University of South Carolina

This author has no relevant disclosures.Rick Schnellmann, University of Arizona This author has no relevant disclosures.

63Placental Mesenchymal Stromal Cells Improve Forelimb Motor Function in a Rodent Cervical Spinal Cord Contusion ModelWednesday, May 02, 2018 03:25 PM - 04:25 PMLearning Objectives:Describe the impact of acute, intrathecal treatment with placental mesenchymal stromal cells on forelimb functional recovery after unilateral cervical spinal cord injury in an established rodent model.

Participants:Vanover M, Pivetti C, Kumar P, Chung K, Galganski L, Farmer D, Wang AUniversity of California, Davis , Sacramento , California, USAMelissa Vanover, MDUniversity of California, Davis Bio:Melissa Vanover, MD, is a Research Fellow in the Surgical Bioengineering Laboratory at the University of California, Davis. After receiving a Bachelor’s degree in sculpture and scientific illustration at the School of the Art Institute of Chicago in 2005, Vanover completed post-baccalaureate coursework at Indiana University-Purdue University Indianapolis prior to earning her Medical degree from the University of Texas Health Science Center San Antonio in 2013. She is currently a fifth-year resident in the Surgery Department at the University of California, Davis in Sacramento, California. Dr. Vanover is completing two years of dedicated research in the UC Davis Surgical Bioengineering Laboratory, co-directed by Diana Farmer, MD, and Aijun Wang, PhD. The Surgical Bioengineering Laboratory has received research funding support from the National Institutes of Health (NIH), California Institute for Regenerative Medicine (CIRM), Shriners Hospital for Children, and March of Dimes Foundation. Their research focuses primarily on tissue engineering approaches for in utero treatment of congenital disorders, such as spina bifida, hemophilia, and congenital diaphragmatic hernia, utilizing placental mesenchymal stromal cells.Education:The School of the Art Institute of Chicago (Chicago, IL), BFA 2002-2005, Sculpture and Scientific Illustration Indiana University-Purdue University Indianapolis (Indianapolis, IN), 2007-2009, Post-Baccalaureate University of Texas Health Science Center San Antonio (San Antonio, TX), MD 2009-2013, Medicine University of California, Davis (Sacramento, CA), 2013-present, General Surgery ResidentThis author has no relevant disclosures.

Christopher Pivetti, MSUniversity of California, Davis This author has no relevant disclosures.Priyadarsini Kumar, PhDUniversity of California, Davis This author has no relevant disclosures.Karen Chung, BSUniversity of California, Davis This author has no relevant disclosures.Laura Galganski, MDUniversity of California, Davis This author has no relevant disclosures.Diana Farmer, MDUniversity of California, Davis This author has no relevant disclosures.Aijun Wang, PhDUniversity of California, Davis This author has no relevant disclosures.

64Applications for 2D and 3D configurations of hybrid OPF+ scaffolds to investigate neuroregeneration in vitro and in vivo following spinal cord injuryWednesday, May 02, 2018 03:25 PM - 04:25 PMLearning Objectives:Discuss the potential of using combinational therapy approaches that utilize biomaterials, ECM molecules, growth factors, and cell therapies to treat spinal cord injury.

Participants:1Siddiqui A, 1Madigan N, 2Brunner R, 1Liu X, 3Schwarzbauer J, 3Harris G, 3Schwartz J, 1Lu L, 1Yaszemski M, 1Windebank A1Mayo Clinic , Rochester , Minnesota, United states; 2Paracelsus Medical University , Salzburg , , Austria; 3Princeton University , Princeton , New jersey, United statesAhad Siddiqui, PhDMayo Clinic Bio:Dr. Ahad M. Siddiqui is a Post-Doctoral Research Fellow in the Regenerative Neurobiology laboratory under the supervision of Dr. Anthony Windebank at the Mayo Clinic in Rochester, Minnesota. In 2009, he completed his undergraduate degree at the University of Toronto with a double major in Biology and Psychology. His interest in the biological aspects of psychology led him to choose to do his Ph.D. in neuroscience, which he completed in 2013 at McMaster University (Hamilton, Ontario, Canada) in Dr. Alexander K. Ball’s lab. His research looked at how microglia transplanted in different activation states would affect the survival and regeneration of retinal ganglion cells after optic nerve injury. As a result of his thesis work he

received the Faculty of Health Sciences Graduate Program Excellence Award. Dr. Siddiqui then went on to do a Post-Doctoral Research Fellow at the University Health Network/University of Toronto in the Fehlings¹ laboratory for neural repair and regeneration. Here his research focused on how cell therapies could modulate the microenvironment to encourage regeneration after spinal cord injury. His work looked at the effects of human umbilical cord derived mesenchymal stromal cells infusion after spinal cord injury, particularly emphasizing the inflammatory response and vascular repair. He also examined the use of genetically modified human iPSC and ESC derived neural stem cells to express compounds that could aid in recovery after cervical spinal cord injury. His research at Mayo Clinic now looks at how different combinatorial treatment strategies using novel biomaterials, genetically modified cells, pharmaceuticals, electrical stimulation, and rehabilitative strategies can work together to promote regeneration and repair after spinal cord injury. Education:Honours Bachelor of Science (H.B.Sc.) - 2005 - 2009 University of Toronto (Mississauga, Ontario, Canada) Double major in Biology and Psychology

Doctor of Philosophy (Ph.D.) - 2009 - 2013 McMaster University (Hamilton, Ontario, Canada) McMaster Integrated Neuroscience Discovery & Study (MiNDS; Graduate Neuroscience Program)

This author has no relevant disclosures.Nick Madigan, MD, PhDMayo Clinic This author has no relevant disclosures.Rosa Brunner, Paracelsus Medical University This author has no relevant disclosures.Xifeng Liu, PhDMayo Clinic This author has no relevant disclosures.Jean Schwarzbauer, PhDPrinceton University This author has no relevant disclosures.Gregory Harris, PhDPrinceton University This author has no relevant disclosures.Jeffrey Schwartz, PhDPrinceton University This author has no relevant disclosures.Lichun Lu, PhDMayo Clinic

This author has no relevant disclosures.Michael Yaszemski, MD, PhDMayo Clinic This author has the following disclosures:

Other (see below)Drs. Windebank and Yaszemski, along with the Mayo Clinic, hold protected intellectual property on scaffolds and polymers. This has not been licensed and has not generated any income. Anthony Windebank, MDMayo Clinic This author has the following disclosures:

Other (see below)Drs. Windebank and Yaszemski, along with the Mayo Clinic, hold protected intellectual property on scaffolds and polymers. This has not been licensed and has not generated any income.

65The use of embedded optical fibers to assess the transient compression distribution at key locations of an instrumented spinal cord surrogateWednesday, May 02, 2018 03:25 PM - 04:25 PMLearning Objectives:Description of an innovative technology for the continuous recording of the dynamic compression distribution within soft materials

Participants:1Facchinello Y, 2Wagnac E, 2Ung B, 2Petit Y, 2Pradhan P, 1Mac-Thiong J1Research Center, Hôpital Du Sacré-Coeur De Montréal , Montréal , QC, Canada; 2École De Technologie Supérieure , Montreal , QC, CanadaYann Facchinello, PhDResearch Center, Hôpital Du Sacré-Coeur De Montréal This author has no relevant disclosures.Eric Wagnac, PhDÉcole De Technologie Supérieure This author has no relevant disclosures.Bora Ung, PhDÉcole De Technologie Supérieure This author has no relevant disclosures.Yvan Petit, PhDÉcole De Technologie Supérieure This author has no relevant disclosures.Prabin Pradhan, École De Technologie Supérieure This author has no relevant disclosures.

Jean-Marc Mac-Thiong, PhD, MDResearch Center, Hôpital Du Sacré-Coeur De Montréal Bio:Jean-Marc Mac-Thiong, MD, PhD, is a clinician-scientist practicing as an orthopedic spine surgeon at the Hopital du Sacre-Coeur de Montreal, with a multidisciplinary background in spine surgery (MD, fellowship), biomedical sciences (MSc, PhD), and engineering (BEng). He is an associate professor of surgery and research director of the Orthopedics Division at Université de Montréal. He is Chairman of the Medtronic Research Chair in spinal trauma at Université de Montréal and in charge of the Rick Hansen Spinal Cord Injury Registry at Hopital du Sacre-Coeur de Montreal. He is Chair of the Spine/Acute care Committee at the American Spinal Injury Association. His research has been supported by the Canadian Funds for Innovation, Natural Sciences and Engineering Research Council of Canada, Department of the US Army, Fonds de recherche du Québec – Santé, Fonds de recherche du Québec – Nature et technologies, and Scoliosis Research Society. He has focused his research on acute predictors of the outcome after a traumatic spinal cord injury, and on the biomechanical and experimental characterization of traumatic spinal cord injury.Education:École Polytechnique de Montréal, Canada, B.Eng. 1997, Mechanical engineering Université de Montréal, Canada, M.S., 2001, Biomedical Sciences Université de Montréal, Canada, M.D., 2002, Medicine Université de Montréal, Canada, Residency, 2007, Orthopedic surgery Université de Montréal, Canada, Ph.D., 2008, Biomedical Sciences Twin Cities Spine Center, Minneapolis, USA, Fellowship, 2008, Spine surgery

This author has the following disclosures: Research Support Shareholder

Co-founder and shareholder (30%) of Spinologics Inc. Head of Medtronic Research Chair in spinal trauma at University of Montreal Financial support from Medtronic of Canada for 1 fellow per year in spinal surgery at Hopital du Sacre-Coeur de Montreal

66Neuroprotective Effects of Spirulina Platensis on The Spinal Cord Following Spinal Cord Injury in Rat Models: Locomotor Activity and Ultrastructural StudyWednesday, May 02, 2018 03:25 PM - 04:25 PMLearning Objectives:To examine the ultrastructural changes following neuroprotection and functional recovery induced by S, platensis in spinal cord-injured rat models.

Participants:1Abdullahi D, 2Annuar A, 3Sanusi J1Department of Anatomy, College of Medical Sciences, Abubakar Tafawa Balewa University , Bauchi , Bauchi sta, Nigeria; 2Department of Biomedical Science, Faculty of Medicine,

University of Malaya , Kuala Lumpur , Kuala lump, Malaysia; 3Department of Anatomy, Faculty of Medicine, University of Malaya , Kuala Lumpur , Kuala lump, MalaysiaDauda Abdullahi, M.Med.Sc (Master of Medical Science)Department of Anatomy, College of Medical Sciences, Abubakar Tafawa Balewa University Bio:Dauda Abdullahi has completed M.Med.Sc with Distinction from the University of Malaya (QS World University Ranking: 114), the premier and the top University in Malaysia. He's appointed as Tutor and Teaching Assistant involved in the Gross and Microscopic Anatomy practical teaching to Medical (MBBS) students in Faculty of Medicine, University of Malaya, Malaysia due to his excellent academic and research performances. He has previously taught Neuroanatomy to the Post-Basic Psychiatric Nursing students in the Federal Neuropsychiatric Nursing, Calabar Nigeria. He was also previously involved in the practical teaching of Regional Anatomy to Medical (MBBS) students as a Graduate Assistant in the Usmanu Danfodiyo University, Sokoto, Nigeria. He is currently an academic staff on Fellowship (study leave) with the Department of Anatomy, College of Medical Sciences, Abubakar Tafawa Balewa University, Bauchi, Nigeria. He utilizes both Electron Microscopic and Immunofluorescence techniques to to unravel the enigma in neuroprotection and repair of spinal cord injury.Education:BSc. (Hons) Human Anatomy (With CGPA of 4.42 out of 5.00): College of Medical Sciences, University of Maiduguri, Nigeria. M.Med.Sc. (Distinction): Faculty of Medicine, University of Malaya, Malaysia. This author has no relevant disclosures.Azlina Annuar, Ph.DDepartment of Biomedical Science, Faculty of Medicine, University of Malaya Bio:Dr Azlina Anuar Ahmad is a Senior Lecturer in Department of Molecular Medicine, Faculty of Medicine, University Malaya since 2006. She holds a degree in Bachelor of Science in Neuroscience from University College London in 1998, before pursuing her PhD degree in 2000 at Imperial College, London. Upon completion of her PhD in 2004, she then joined Dr. Patricia Salinas in University College London for her 2-year postdoctoral research training, working on the role of the Wnt signaling pathway in synapse formation and neurotransmitter release. Her current research interests are the genetics and synapse formation of the brain. Among all, her work includes looking at expression of miRNAs in the brain, particularly in cultured hippocampal neurons and synapse formation, and mutation screening in patients with neurodegenerative diseases. She has published a number of publications in prestigious journals such as Journal of Cell Biology, Current Opinion Neurology, PLoS Genetic, Gene and Science.Education:BSc. (1998), University College London Ph.D (2004), Imperial College, London. This author has no relevant disclosures.Junedah Sanusi, Ph.DDepartment of Anatomy, Faculty of Medicine, University of Malaya Bio:Dr. Junedah Sanusi is an Associate Professor in the Department of Anatomy, Faculty of Medicine, University of Malaya. She holds various administrative positions in the University of

Malaya. Her area of expertise include spinal cord injury, motoneurone pool, afferent activity, motoneurone development, locomotor function, nutritional supplements.Education:BSc. (KANSAS), KANSAS STATE UNIVERSITY, MANHATTAN

MSc. (KANSAS), KANSAS STATE UNIVERSITY, MANHATTAN

PHD(LONDON), UNIVERSITY COLLEGE LONDON, GOWER STREET LONDON WC1 This author has no relevant disclosures.

67Lipoxin A4 and Resolvin D1 Preserve Neural Inductive Capacity of Dental Pulp Stem Cells Cultured under Inflammatory ConditionsImplications for SCI Stem Cell Therapy Wednesday, May 02, 2018 03:25 PM - 04:25 PM

Participants:1Morse L, 1Nguyen N, 1Xu Y, 1Hasturk H, 1Kantarci A, 2Battaglino R1Craig Hospital , Englewood , CO, United states; 2Uc Denver , Aurora , CO, 80113Leslie Morse, Craig Hospital Bio:Medical Director of SCI Research, Craig Hospital. Co-Project Director of the Rocky Mountain Regional Spinal Injury SystemEducation:DO: University of New England Residency: PMR, Boston Medical CenterThis author has the following disclosures:

Research SupportNIH, NIDLRRNguyen Nguyen, MPHCraig Hospital This author has no relevant disclosures.Yan Xu, Craig Hospital This author has no relevant disclosures.Hatice Hasturk, Craig Hospital This author has no relevant disclosures.Alp Kantarci, Craig Hospital This author has no relevant disclosures.

Ricardo Battaglino, PhDUc Denver This author has the following disclosures:

Research SupportNIH

68The Role of Upper Extremity Surgery in Patients with TetraplegiaWednesday, May 02, 2018 03:25 PM - 04:25 PMLearning Objectives:1. Review the benefits of upper extremity reconstructive surgery in patients with tetraplegia. 2. Discuss the barrier and challenges for patients with spinal cord injury to consider prior to undergoing upper extremity surgery. 3. Learn the surgical treatment options available to restore upper extremity function in patients with tetraplegia.

Participants:Rhee P, Garlanger K, K RMayo Clinic , Rochester , , United states of americaPeter Rhee, DO, MSMayo Clinic Bio:Dr. Peter Rhee is currently a hand and microvascular surgeon within the Department of Orthopedic Surgery at the Mayo Clinic in Rochester, MN. He holds academic appointment as an Associate Professor of Orthopedic Surgery through the Mayo Clinic College of Medicine and Associate Professor of Surgery through the F. Edward Hebert School of medicine. He is board certified in orthopedic surgery with a Certificate of Added Qualification in Hand Surgery through the American Board of Orthopedic Surgery.

Dr. Rhee graduated as Valedictorian of his medical school class at the Kirksville College of Osteopathic Medicine (Kirksville, MO). He completed his orthopedic surgery residency and hand surgery fellowship at the Mayo Clinic while obtaining his Master of Science degree in Orthopedic Research from the Mayo Graduate School.

He then served in the United States Air Force as the Chief of Hand and Microvascular Surgery at the San Antonio Military Medical Center (Fort Sam Houston, TX), Director of the Microvascular Surgery Research Lab (Fort Sam Houston, TX), and Chief Hand Surgeon at the Center for the Intrepid Advanced Rehabiliation Center (Fort Sam Houston, TX) from 2013 until 2017.

Dr. Rhee has presented over 60 regional, national, and international presentations, has authored 42 peer-reviewed articles, 2 editorials, and 5 book chapters. He also serves on 8 committees for the American Society for Surgery of the Hand and 1 committee for the American Association for Hand Surgery. Dr. Rhee is a reviewer for the Journal of Hand Surgery America, American Journal of Orthopedics, Journal of Clinical Biomechanics, and Hand Surgery.

Education:Grinnell College (Grinnell, IA), BA 1999-2003 Biology

Kirksville College of Osteopathic Medicine (Kirksville, MO), DO 2003-2007

Mayo Clinic (Rochester, MN), Orthopedic Surgery Residency 2007-2012

Mayo Clinic (Rochester, MN), BS 2008-2012 Orthopedic Surgery Research

Mayo Clinic (Rochester, MN), 2012-2013 Hand and Microvascular Surgery FellowshipThis author has no relevant disclosures.Kristin Garlanger, DOMayo Clinic Bio:Dr. Kristin Garlanger is from the southwest suburb of Chicago called Orland Park, IL. She attended the University of Illinois where she enjoyed cheering for the Illini basketball and football teams and where she met her husband Greg. She received her Masters and DO degree at Midwestern University (Chicago College of Osteopathic Medicine) and stayed an extra year to do an OMM fellowship. Dr. Garlanger completed her internship year at Illinois Masonic Hospital in Chicago before completing her physical medicine and rehabilitation residency at Mayo Clinic. Following residency, she completed a spinal cord injury medicine fellowship at the Medical College of Wisconsin before joining the staff at Mayo Clinic. Her special interests within the SCI field include adaptive sports and the health and wellness of those with spinal cord injury. She is heavily involved in the local Rochester Sled Hockey team. Kristin and Greg enjoy golfing, running races that have great scenery and spending time with their daughter Lyla. Education:University of Illinois Champaign (Urbana, IL), BS 2002-2006 Molecular and Cellular Biology

Midwestern University (Downers Grove, IL), MS 2006-2009 Biomedical Sciences

Chicago College of Osteopathic Medicine (Downers Grove, IL), DO 2007-2021

Chicago College of Osteopathic Medicine (Downers Grove, IL), Osteopathic Manipulative Medicine (OMM) Pre-Doctoral Teaching and Research Fellowship 2009-2012

Illinois Masonic Medical Center (Chicago, IL), Traditional Osteopathic Rotating Internship 2012-2013

Mayo School of Graduate Medical Education (Rochester, MN), Physical Medicine and Rehabilitation Residency 2013-2016

Zablocki VA Medical Center/Medical College of Wisconsin (Milwaukee, WI), Spinal Cord Injury Fellow 2016-2017This author has no relevant disclosures.

Ronald K, MDMayo Clinic Bio:

Ronald K. Reeves, MD is an attending physician at Mayo Clinic in Rochester Minnesota. Dr Reeves earned his B.A. degree from Brandeis University in Waltham Massachusetts and his MD degree from Mayo Clinic College of Medicine. He also completed his PM&R residency at Mayo Clinic. He is a Fellow of the American Academy of Physical Medicine and Rehabilitation and subspecialty certified in Spinal Cord Medicine. Dr Reeves’ has been recognized with presentation awards from the American Spinal Injury Association, excellence in teaching from the Mayo Medical School, the Mayo Clinic Service Excellence Award, PM&R teacher of the Year and a Mayo Clinic Practice Innovation Award. Dr Reeves clinical practice, research and educational activities focus heavily on spinal cord medicine. He previously served as the Mayo Clinic Department of PM&R Vice Chair, Inpatient Rehabilitation Medical Director and the SCI Medical Director. Dr Reeves speaks regularly at National and International venues regarding his non-traumatic spinal cord injury research and SCI education in general. He’s a member of the ASIA Board of Directors and serves on the International Spinal Cord Society Education Committee. Education:1984-1988 Brandeis University: BA, Biology and Psychology

1990-1994 Mayo Medical School: MD

1994-1995 Mayo Graduate School of Medicine, College of Medicine, Mayo Clinic Internship, Internal Medicine

1995-1998 Mayo Graduate School of Medicine, College of Medicine, Mayo Clinic Residency, Physical Medicine and Rehabilitation

This author has no relevant disclosures.

69Clinical Trials 360°, sponsored by Spinal Cord Outcomes Partnership Endeavor (SCOPE)Wednesday, May 02, 2018 01:45 PM - 03:15 PMLearning Objectives:1. Discuss translation of research programs from the pre-clinical to clinical stage. 2. Describe the current status of the highlighted clinical trials. 3. Assess the current challenges in clinical trials.

Participants:Jones LCraig H. Neilsen Foundation , Encino , California, United statesLinda Jones, MS, PTCraig H. Neilsen Foundation

Bio:Linda Jones is a Program Officer for the Spinal Cord Injury Research on the Translational Spectrum (SCIRTS) program. She co-manages the funding portfolio that spans mechanistic, translational and early clinical research aimed at improving recovery from spinal cord injury. With over 20 years of experience, Linda has applied her clinical expertise, serving as a consultant and staff member in a number of pharmaceutical, biotechnology, exoskeleton and healthcare settings. She worked at Geron Corporation from 2006-2011, preparing and managing the first clinical trial in the United States utilizing cells derived from human embryonic stem cells, in a Phase I study in patients with neurologically complete, sub-acute spinal cord injury. Prior to this, she worked with Proneuron Biotechnologies, the sponsor of the first Phase 1 cell-based study (autologous macrophage injection) in spinal cord injury, and subsequently managed the Phase II trial. Linda also worked at Denver Health Medical Center for 12 years, with a focus on physical therapy interventions in the intensive care unit. As a result of this background, Linda has experience reviewing preclinical data and integrating necessary components of these findings into the clinical trial/protocol, assessing the feasibility of trial implementation, developing the operational infrastructure to execute trials and addressing regulatory challenges. Her focus has been on applying lessons from an operational perspective that are learned in clinical trials and addressing gaps in outcome measures used in such trials. Publications have focused on results and “lessons learned” from the Proneuron trial as well as the natural history of recovery (based on data from the European Multicenter Study about Spinal Cord Injury – EMSCI) and outcome measures in spinal cord injury. Linda has also participated in publications on updates to and challenging cases based on the International Standards for the Neurological Classification of Spinal Cord Injury. Linda has been a guest lecturer at the University of Colorado, as well as a guest lecturer, affiliate faculty and instructor at Regis University, with a focus on complex systems, critical care, and neuroscience. She currently sits on several committees within professional organizations addressing spinal cord injury. Linda completed her Advanced Master’s Degree in neurological physical therapy from Samuel Merritt College and her undergraduate degrees in kinesiology and physical therapy from the University of Colorado. She is currently enrolled in a Doctoral Program at the University of Colorado in Clinical Science, in the Clinical Investigation track. Education:Coursework towards a PhD in Clinical Research, Clinical Investigation track• 2014-present University of Colorado, Denver, CO

Advanced Masters of Science in Neurological Physical Therapy • 1996-2001 Samuel Merritt College, Oakland, CA Thesis: “Reliability and Validity of the Acute Care Index of Function in the Critically III”

Bachelor of Science in Physical Therapy • 1998-1990 University of Colorado, Denver, CO

Bachelor of Science in Kinesiology • 1983-1988 University of Colorado, Boulder, CO This author has the following disclosures:

Other (see below)Employee of the Craig H. Neilsen Foundation

70Opposing views – Re-use of catheters: Yea or NayWednesday, May 02, 2018 04:40 PM - 05:40 PMLearning Objectives:Objectives: 1. To introduce and discuss Pros (i.e. gold standard for urinary tract management) and Cons (e.g. urinary tract infection (UTI) of intermittent catheterization in individuals following spinal cord injury (SCI).

2. To present Pros vs Cons on single versus re-use of catheters for intermittent catheterization in individuals SCI.

3. To present and discuss our independent appraisal of the 2014 Cochrane review on “Intermittent catheterization for long-term bladder management”, which led to the withdrawal of the 2017 version.

Participants:1Krassioukov A, 2Kennelly M, 1Walter M1International Collaboration on Repair Discoveries (Icord), Faculty of Medicine, University of British Columbia , Vancouver , BC, Canada; 2Department of Urology, Carolinas Medical Center , Charlotte , NC, USAAndrei Krassioukov, MD, PhD, FRCPCInternational Collaboration on Repair Discoveries (Icord), Faculty of Medicine, University of British Columbia Bio:PERSONAL STATEMENT: Both my research and clinical work are related to spinal cord injury, autonomic dysfunctions, and disability issues. As a leader in a distinct and specialized field, I have published 90 peer-reviewed publications in the past five years, which have collectively been cited over 437 times with an h-index of 31 (Web of Science). I was the PI on 78 of these publications, with my trainees as first authors on 49 of them. I have received a number of recognition for the best published research in the area of SCI (ASIA Awards 2003, 2014). Also during the past five years I have provided 69 invited/plenary/keynote addresses at international and national meetings (e.g., International Society of Physical Medicine Association, Latin American Congress of PM&R, etc.). In recognition of research excellence and leadership I was elected a Fellow of the Canadian Academy of Health Science in 2010.

CURRENT DUTIES: Presently, I am a Professor of Medicine and Chair of Rehabilitation Medicine at the University of British Columbia and a staff physician at the spinal cord injury (SCI) program at the GF Strong Rehabilitation Centre in Vancouver. I am also a head of the Autonomic Dysfunctions Laboratory and Co-Director of ICORD, Vancouver. As a clinician-scientist I spend approximately 60% of my time with my research and 40% with my clinical duties. Both my

research and clinical work are related to spinal cord injury, autonomic dysfunctions and disability issues. Presently, I am a primary research supervisor of three postdoctoral fellows, one medical residents, one MD PhD student, one PhD student, two master students, and four medical students. Experimental animal, human clinical studies, and knowledge translation research are incorporated in ongoing projects in my laboratory.

CONTRIBUTION TO SCIENCE: The following are my most significant knowledge translation contributions to the field of spinal cord injury: • My award winning CIHR-funded “ABC of AD”, an educational web-based program for paramedics won 2 awards from the 2013 Horizon Interactive Awards, and is currently being considered for inclusion in the BC Ambulance Service’s curriculum. The program is designed to empower first responders with evidence-informed disease managements approaches. • I developed the International Autonomic Standards after SCI, and implemented these standards around the world to improve evidence-informed healthcare practices. • My research on the effect of autonomic dysfunction on exercise performance in athletes with SCI has led to the creation of autonomic assessments for athletes, which are currently being proposed to the IPC for inclusion into their classification. These issues have also been communicated to the community via a 2012 CIHR-funded Café Scientifique and represent a major contribution to health care focused on prevention and management of secondary conditions after SCI. • I published the “direly needed” book PleasureAble, which focused on sexual activity after SCI and other disabilities and has received significant international attention.Education:Volgograd State Medical Institute, Volgograd, Russia / MD / 06/1979 / Medicine

Pavlov Institute of Physiology, The Academy of Sciences of Russia, St. Petersburg, Russia / PhD / 04/1983 / Medicine / Neurophysiology

John P. Robarts Research Institute, London, ON, Canada / Fellow / 08/1991 – 09/1994 / Spinal Cord Injury / Neurophysiology

University of British Columbia / FRCPC / 06/2006 / Board Examinations in Physical Medicine and RehabilitationThis author has the following disclosures:

Research Support Other (see below)

ONGOING RESEARCH SUPPORT 1. Craig H. Neilsen Foundation QOL Project Grants. Title: Motherhood after spinal cord injury: lactation, breastfeeding, and autonomic dysreflexia. Period: 2016-2017 ROLE: PI

2. Heart and Stroke GIA 2016/17. Title: When are blood vessels “ready to rupture”? Cerebrovascular health following spinal cord injury: from animal models to clinical practice. Period: 2016 – 2019

ROLE: PI

3. Pfizer Canada Inc. Title: A Phase II, Open-Label Exploratory Study Investigating the Efficacy of Toviaz for Treatment of Adult Patients with Spinal Cord Injury (SCI) with Neurogenic Detrusor Overactivity (NDO) for Amelioration of Autonomic Dysreflexia (AD). Period: Nov 2015 –Feb 2017 ROLE: PI

4. Rick Hansen Institute. Title: Development of a mobile app (telephone/iPod application) for emergency department physicians on recognition and management of life-threatening episodes of autonomic dysreflexia: “ABC of AD for the EM doc”. Period: Apr 2015-Dec 2016. ROLE: PI

5. Vancouver Foundation. Title: Vancouver Foundation Start-up Funds: Period: April 2015 – March 2017 ROLE: PI

6. Christopher and Dana Reeve Foundation. Title: Big Idea Cardiovascular Committee. Period: Feb 2015-Aug2015. ROLE: PI

7. Rick Hansen Institute/ RHI Pilot Studies - Optimizing Neurorecovery Following SCI. Title: Effect of epidural stimulation on cardiovascular control following spinal cord injury. Period: Mar 2015-Mar 2017. ROLE: PI

8. Rick Hansen Foundation/International Collaboration On Repair Discoveries (ICORD)/Seed Grants. Title: Development of evidence-based guidelines for blood pressure management during iatrogenically-induced autonomic dysreflexia in those with spinal cord injury: the limits of cerebral autoregulation. Period: Apr 2014-Jun 2016. PI: Dr. Stacy Elliott. ROLE: Co-Investigator

9. Department of Defense USA. Title: Alleviating autonomic dysreflexia after spinal cord injury. Period: September 2014-August 2017. ROLE: PI

10. Craig H. Neilsen Foundation/ Neilsen Senior Research Grant. Title: Cardiac function after spinal cord injury: from bench to bedside. Period: July 2013-June 2017. ROLE: PI 11. Rick Hansen Institute. Title: Validation of the International Autonomic Standards for evaluation of individuals with chronic spinal cord injury. Period: March 2013- March 2017. ROLE: PI

12. Rick Hansen Foundation. Title: Improving Cardiovascular Health for Canadians Living with SCI: Effects of Exercise, sex Differences, and Targeted Clinical Education. Period: April 2012-March 2017. ROLE: PI

13. Rick Hansen Institute / Operating Grant. Title: BOTOX treatment for neurogenic detrusor hyperreflexia and prevention of autonomic dysreflexia following spinal cord injury. Period: July 2012 – Jan. 2017. ROLE: PI

14. Canadian Institutes of Health Research (CIHR) / Chronic disease risk and intervention strategies team grant. Title: Improving cardiovascular health for Canadians living with spinal cord injury: effects of exercise and targeted education. Period: Dec. 2011-Nov. 2016. ROLE: PI

15. Craig H. Neilsen Foundation/Christopher and Dana Reeve Foundation. Title: Recovery of cardiovascular function with epidural stimulation after human spinal cord injury. Period: January 2015-December 2017. PI: Dr. Susan Harkema ROLE: Co-Investigator

16. Canadian Institutes of Health Research (CIHR) / Operating grant. Title: Beyond VO2peak: Understanding exercise-induced changes in cardiovascular function after stroke. Period: 2011-2015. PI: Dr. J. Eng ROLE: Co-Investigator

17. International Spinal Research Trust / Operating grant. Title: Peripheral Sympathetic and sensory plasticity in bladder and bowel circuitry in chronic spinal cord injury. Period: Jan. 2011-Aug. 2014. PI: Dr. M. Ramer ROLE: Co-Investigator

18. Rick Hansen Institute Start Up Funds. Title: Rick Hansen Institute Start-Up Funds. Period: March 2007 – March 2020. ROLE: PI

OTHER: Coloplast and WellSpect Michael Kennelly, MD, FACSDepartment of Urology, Carolinas Medical Center Bio:Personal Statement

I currently hold various faculty teaching positions in the Departments of Urology and Gynecology at Carolinas Medical Center and University of North Carolina – Chapel Hill. Administratively, I am the Medical Director of the Charlotte Continence Center at Carolinas Medical Center, Director of Urology at Carolinas Rehabilitation Hospital, Co-Director of the Women’s Center for Pelvic Health, and Clinical Professor in the Department of Surgery, Division of Urology at University of North Carolina – Chapel Hill.

My foundation of academic interests developed during my fellowship training in female urology, neurourology, urodynamics, and reconstructive urology and during my American Urologic Association Research Scholar projects (1994 – 1995) with an emphasis on neuropharmacologic treatments and urodynamic effects in neurogenic bladder and detrusor sphincter dyssynergia.

I am dual boarded as a Diplomat of The American Board of Urology with certification in Female Pelvic Medicine and Reconstructive Surgery and Fellow of the American College of Surgeons. I continue to be very active in professional societies (member of more than 15 professional organizations) and I continue to hold several leadership positions such as Past President of the American Spinal Injury Association, member of the Board of Directors of the Academy of Spinal Cord Injury Professionals, President of the American Paraplegic Society, Board of Directors of the Society of Urodynamics and Female Urology, and Chair of the Urology Care Foundation Bladder Health Committee.

My research interests are in the areas of urinary incontinence, voiding dysfunction, pelvic reconstruction surgery, and neurourology where I have been principal investigator in over 60 clinical trials. I maintain active academic pursuits in authoring or coauthored several journal articles, book chapters, and educational videos in the areas of urinary incontinence and neurourology and have lectured regionally, nationally and internationally on these topics.Education:University of Notre Dame, Notre Dame, Indiana / BS / 05/1985 / Science

University of Cincinnati, Cincinnati, Ohio / MD / 06/1989 / Medicine

University of Michigan Medical Center, Ann Arbor, Michigan / Internship / 06/1991 / Surgery

University of Michigan Medical Center, Ann Arbor, Michigan / Residency / 06/1994 / Urology

University of Texas at Houston, Houston, Texas / Fellowship / 06/1995 / Neurourology

CERTIFICATION AND LICENSURE: 1990 National Board of Medical Examiners #369657 1991 Foundations in Microsurgical Skills 1992 Michigan State Medical Board #4301054650 1993 Basic Life Support 1993 Advanced Cardiac Life Support

1993 Urological Laparoscopy 1994 Texas State Medical Board #J7029 1994 American Board of Urology - Part I 1995 North Carolina Medical Board - #95-00634 1997 American Board of Urology - Part II (Board Certified) 1998 American College of Surgeons – Fellow 1998 Bladder Suspension & Pelvic Floor ReconstructionPreceptorship 1999 Interstim Course 2000 American Board of Urology – Re-certification 2013 Female Pelvic Medicine and Reconstructive Surgery 2015 Maintenance of Certificate – American Board Of UrologyThis author has the following disclosures:

Research Support Consultant

Research Support - Allergan, Boston scientific, Coloplast, Contura, Cook Myosite, Dignify Therapeutics, Taris

Consultant - Allergan, Astellas, Boston Scientific, CogentixMatthias Walter, MD, FEBUInternational Collaboration on Repair Discoveries (Icord), Faculty of Medicine, University of British Columbia Bio:Matthias Walter graduated in 2006 with a degree in medicine from the Friedrich-Schiller-University Jena, Germany. In 2014, he completed his MD thesis about the outcome and complications of intrathecal baclofen therapy in children at the University of Zurich. His residency included clinical training in General Surgery, Pediatric Surgery and Urology. Between December 2011 and 2014 he worked as a full-time PhD candidate at the Spinal Cord Injury Centre and Research, University of Zürich, Balgrist University Hospital, Zürich, Switzerland. He completed his residency in Urology and passed the board certification examination of the Swiss Association of Urology at the Cantonal Hospital Aarau in September 2016. He has been board certified as a Urologist by the Swiss Society of Urology and is a fellow of the European Board of Urology (FEBU). Since November 2016, he is a postdoctoral research fellow at the International Collaboration on Repair Discoveries (ICORD), Blusson Spinal Cord Centre, University of British Columbia, Vancouver, Canada. Since September 2017, he is a Michael Smith Foundation for Health Research (MSFHR) and Rick Hansen Institute (RHI) Research Trainee.Education:UNIVERSITY

Friedrich Schiller University Jena, Germany / Medicine (M.D.) / 04/2006

University of Zurich, Switzerland / Doctorate in Medicine (Dr. med.) / 01/2014 / Pediatrics

RESIDENCY AND BOARD CERTIFICATION

Cantonal Hospital Aarau, Switzerland / Urologist / 10/2016 / Residency Urology

European Board of Urology / Fellow of the European Board of Urology (FEBU) / 10/2016 / UrologyThis author has the following disclosures:

Research Support2017 Michael Smith Foundation for Health Related (MSFHR) Postdoctoral Research Trainee Award Recipient, co-funded by the Rick Hansen Institute (RHI); WellSpect Research Grant-in-Aid Recipient

71Surgically implanted nerve cuff electrodes stabilize rapidly and preserve chronic nerve health in anatomically challenging locationsThursday, May 03, 2018 07:00 AM - 08:00 AMLearning Objectives:To understand the acute and chronic time course of neurophysiological responses to stimulating nerve cuff electrodes on the peripheral nerves in terms of conduction velocities, compound motor unit action potentials, sensory nerve action potentials, stimulus threshold stability and overall neuromuscular function.

Participants:1Freeberg M, 2Gilles P, 2Lombardo L, 3Dustin T, 2Ansari R, 4Triolo R1Case Western Reserve University , Cleveland , , USA; 2Louis Stokes Cleveland Va Medical Center , Cleveland , , USA; 3Case Western Reserve University/Cleveland Va Medical Center , Cleveland , , USA; 4Case Western Reerve University/Cleveland Va Medical Center , Cleveland , OH, USAMax Freeberg, Ph.D.Case Western Reserve University This author has no relevant disclosures.Pinault Gilles, M.D.Louis Stokes Cleveland Va Medical Center This author has no relevant disclosures.Lisa Lombardo, MSPTLouis Stokes Cleveland Va Medical Center This author has no relevant disclosures.Tyler Dustin, Ph.D.Case Western Reserve University/Cleveland Va Medical Center This author has no relevant disclosures.Rahila Ansari, M.D.Louis Stokes Cleveland Va Medical Center This author has no relevant disclosures.

Ronald Triolo, Ph.D.Case Western Reerve University/Cleveland Va Medical Center Bio:Ronald Triolo received a BS in Electrical Engineering from Villanova University, Villanova PA in 1980, and MS degrees in both Biomedical and Electrical Engineering from Drexel University in Philadelphia PA in 1982 and 1984, respectively, followed in 1986 by a doctorate in Biomedical Engineering for the design and clinical testing of an actively powered myoelectrically controlled above-knee prosthesis for trans-femoral amputees. Dr. Triolo was Director of Research at the Philadelphia Shriners Hospital from 1986 through 1994 where he investigated neuroprosthetic and neurotherapeutic uses of neural stimulation for children with spinal cord injury or cerebral palsy. He is currently a tenured Professor of Biomedical Engineering at Case Western Reserve University and a Senior Career Scientist with the Rehabilitation Research & Development Service of the US Department of Veterans Affairs. Dr. Triolo is the Executive Director of the Center for Advanced Platform Technology of the Department of Veterans Affairs where he oversees the design, prototyping and production of novel medical devices and neural interfaces for the rehabilitation of individuals with paralysis, sensorimotor impairments or limb loss. He also directs the Motion Study Laboratory at the Louis Stokes Cleveland Veterans Affairs Medical Center where he pursues original research in the development and clinical application of peripheral nerve approaches for neuroprosthetic, neurotherapeutic and restorative technologies, limb prosthetics/orthotics, and dynamic exoskeletal systems along with the quantitative assessment of their outcomes. Dr. Triolo has authored over 130 peer-reviewed journal articles, 250 conference abstracts, 13 book chapters and 6 patents. He currently leads independently funded research programs sponsored by the NIH, VA, DoD, DARPA and the Craig H. Nielsen Foundation to restore or enhance the upright and seated mobility, posture and balance in individuals with neuro-musculo-skeletal disorders such as stroke, multiple sclerosis and spinal cord injury, and to restore natural sensation to lower limb amputees. Education:Villanova University, Villanova PA BS 1980 Electrical Engineering Drexel University, Philadelphia PA MS 1982 Biomedical Engineering Drexel University, Philadelphia PA MS 1984 Electrical Engineering Drexel University, Philadelphia PA Ph.D. 1986 Biomedical Engineering This author has no relevant disclosures.

72Interventional Pain Medicine in Spine Cord Injury Patients: contributions to the fieldThursday, May 03, 2018 07:00 AM - 08:00 AMLearning Objectives:Discuss current evidence about management and treatment of combination of neuropathic pain and spasticity.

Participants:Macrinici G, Alkhudari A, Torres M, Rahman A, Penmetcha T, Subieta G, Clar SJohn H. Stroger Jr Hospital of Cook County , Naperville , IL, United states

George Macrinici, MDJohn H. Stroger Jr Hospital of Cook County Bio:Position Title: Pain Medicine Fellow, Department of Anesthesiology and Pain Medicine at John H. Stroger, Jr. Hospital of Cook County.

Work Experience 07/2011 –07/2016 Attending Anesthesiologist American Anesthesiology Associates of Illinois, S.C. 19627 South LaGrange Road, Mokena, IL 60448

Education:Previous Residencies/Fellowships 07/01/2017 – present Pain Medicine Fellow, Department of Anesthesiology and Pain Medicine John H. Stroger, Jr. Hospital of Cook County

07/01/2016 – 06/30/2017 Spinal Cord Injury Medicine Fellowship at CWRU/MetroHealth, Cleveland, OH.

07/2007 - 06/2011 Anesthesiology Residency Program University of Kentucky Medical Center, 800 Rose Street, Lexington, KY 40536. This author has no relevant disclosures.Azzam Alkhudari, MDJohn H. Stroger Jr Hospital of Cook County This author has no relevant disclosures.Maria Torres, MDJohn H. Stroger Jr Hospital of Cook County This author has no relevant disclosures.Abed Rahman, MDJohn H. Stroger Jr Hospital of Cook County This author has no relevant disclosures.Taruna Penmetcha, MDJohn H. Stroger Jr Hospital of Cook County This author has no relevant disclosures.Gunar Subieta, MDJohn H. Stroger Jr Hospital of Cook County This author has no relevant disclosures.Steve Clar, MDJohn H. Stroger Jr Hospital of Cook County This author has no relevant disclosures.

73Unique Rehabilitation Challenges in a Pediatric Spinal Cord Injury and Brachial Plexopathy related to Malignancy and Subsequent Oncologic Treatment: a case reportThursday, May 03, 2018 07:00 AM - 08:00 AMLearning Objectives:1. Recognize positive outcomes in a pediatric patient for typical management strategies for neurogenic bladder and bowel despite infection risks incurred by oncology therapy.

Participants:Conlee E, Smither F, Pirius L, Cossette K, Brandenburg J, Driscoll SMayo Clinic , Rochester , MN, United statesErin Conlee, MDMayo Clinic Bio:Erin Conlee, MD, is a Pediatric Rehabilitation Medicine fellow at Mayo Clinic in Rochester, MN. Following a bachelor's of science in Biology and Chemistry from Northwest Nazarene University, she obtained her medical degree at the University of California, San Diego. She completed an Internal Medicine preliminary year and her Physical Medicine and Rehabilitation residency at the Mayo Clinic as well where she served as chief resident her senior year. Her specific interests within the broad field of pediatric rehabilitation include complex neurologic patients, cancer rehabilitation and medical education.Education:Northwest Nazarene University (Boise, ID) BS 2004-2008 Biology & Chemistry University of California, San Diego School of Medicine (La Jolla, CA) MD 2008-2012 Mayo Clinic (Rochester, MN) 2012-2013 Internal Medicine Preliminary Year Mayo Clinic (Rochester, MN) 2013-2016 Physical Medicine & Rehabilitation Mayo Clinic (Rochester, MN) 2016-2018 Pediatric Rehabilitation Medicine This author has no relevant disclosures.Fantley Smither, MDMayo Clinic This author has no relevant disclosures.Linda Pirius, PT, DPTMayo Clinic This author has no relevant disclosures.Kaitlin Cossette, OTMayo Clinic This author has no relevant disclosures.Joline Brandenburg, MDMayo Clinic This author has no relevant disclosures.Sherilyn Driscoll, MDMayo Clinic This author has no relevant disclosures.

74Bariatric surgery for morbid obesity in patient with spinal cord injury – a longitudinal follow up Thursday, May 03, 2018 07:00 AM - 08:00 AMLearning Objectives:We previously reported that bariatric surgery could help morbid obese patients with spinal cord injury1 (SCI) but long-term follow up data is lacking. The objective of the present case report is to report a two year outcome of a patient who underwent bariatric surgery.

Participants:Wong S, Tiberti S, Belci MNational Spinal Injuries Centre, Stoke Mandeville Hospital , Aylesbury , , UKSamford Wong, MSc (Med Sci)., PhD., RDNational Spinal Injuries Centre, Stoke Mandeville Hospital Bio:Samford Wong is NSIC Dietetic Lead in Research / Lead Dietitian, National Spinal Injuries Centre, Stoke Mandeville Hospital Department of Nutrition and Dietetics, Stoke Mandeville Hospital, Buckinghamshire Healthcare NHS Trust, Aylesbury HP21 8AL; Tel: 01296 315775 Education:2004: BSc (Hons)., RD; 2006: MSc (Med Sci); 2010; Dip Adv Diet: 2011; 2012: MPhil / PhD PTLLS: 2013; CMS: 2014 This author has the following disclosures:

Research SupportResearch Grant from Yakult HonshaSimone Tiberti, MDNational Spinal Injuries Centre, Stoke Mandeville Hospital This author has no relevant disclosures.Maurizio Belci, DMS., FRCP., MRCSNational Spinal Injuries Centre, Stoke Mandeville Hospital This author has no relevant disclosures.

75Therapeutic potential of transcutaneous electrical spinal stimulation on upper extremity functions in cervical spinal cord injury: a case studyThursday, May 03, 2018 07:00 AM - 08:00 AMLearning Objectives:

Therapeutic potential of transcutaneous electrical spinal stimulation on upper extremity functions in subjects with cervical spinal cord injuries.

Participants:1Inanici F, 1Samejima S, 2Gad P, 2Edgerton R, 1Hofstetter C, 1Moritz C1University of Washington , Seattle , WA, USA; 2UCLa , Los Angeles , California, USAFatma Inanici, MDUniversity of Washington Bio:Fatma Inanici, MD, is a Research Associate in the Moritz Lab at Department of Rehabilitation Medicine, University of Washington, Seattle, WA, and a graduate student in Center for Sensorimotor Neural Engineering. After graduating from Hacettepe University Medical School, she completed her residency in Physical Medicine and Rehabilitation in the same Institute in 1996. Dr. Inanici has served as a clinician and a faculty in Hacettepe University Medical School, Department of PMR until 2013. She started PhD program in Rehabilitation Science in University of Washington in 2014.Education:Hacettepe University (Ankara, Turkey), MD, 1984-1990, Medical School Hacettepe University (Ankara, Turkey), Residency, 1992-1996, Physical and Rehabilitation Medicine University of Washington, (Seattle, WA), PhC, 2014 - , Rehabilitation Science This author has the following disclosures:

Other (see below)Center for Sensorimotor Neural Engineering, an NSF-ERC (EEC–1028720), research assistant awardSoshi Samejima, PTUniversity of Washington This author has the following disclosures:

Other (see below)Center for Sensorimotor Neural Engineering (CSNE), & UW Institute for Neuroengineering (UWIN), research assistant award Parag Gad, PhDUCLa This author has no relevant disclosures.Reggie Edgerton, PhDUCLa This author has the following disclosures:

ShareholderReggie Edgerton hold shareholder interest in NeuroRecovery Technologies. He is president and chair of company’s board of directors and hold certain inventorship rights on intellectual property licensed by the regents of the University of California to NeuroRecovery Technologies and its subsidiaries.

Christoph Hofstetter, MD., PhD.University of Washington This author has no relevant disclosures.Chet Moritz, PhDUniversity of Washington This author has no relevant disclosures.

76Augmenting Therapy with Transcutaneous Electrical Spinal Cord Stimulation (TSCS) to Improve Walking Function in an Individual with Motor-Incomplete Spinal Cord Injury: A Case ReportThursday, May 03, 2018 07:00 AM - 08:00 AMLearning Objectives:After viewing this poster, clinicians will better understand the impact of TSCS and gait training on walking in a patient with iSCI and describe appropriate clinical interventions to pair with TSCS to optimize walking outcomes.

Participants:McHugh L, Miller AKennedy Krieger Institute , Baltimore , MD, USALiza McHugh, PT, DPT, CMTPTKennedy Krieger Institute Bio:Dr. McHugh has her clinical specialization in novel application of stimulation in patients diagnosed with spinal cord injuries and has developed and implemented transcutaneous spinal cord stimulation (TSCS) treatment protocols for patients diagnosed with spinal cord injuries. Her current research projects include (1) the use of TSCS on motor complete and incomplete SCI to determine differences in walking function and voluntary LE motor function and (2) facilitation of voluntary motor activation utilizing transcutaneous electrical spinal cord stimulation, which was presented in a poster to the American Spinal Cord Injury Association 2016 Annual Meeting. In addition, Dr. McHugh presented a case series on the clinical effectiveness and safety of utilizing TSCS to facilitate voluntary motor control in individuals with chronic tetraplegia and diaphragmatic pacemakers at the American Spinal Cord Injury Association 2017 Annual Meeting.Education:Dr. McHugh received her Bachelors of Science in Athletic Training from The University of Delaware and her Doctorate of Physical Therapy from Washington University in St Louis. Dr. McHugh joined The Kennedy Krieger Institute in 2013 as a Physical Therapist in the International Center for Spinal Cord Injury. In 2016, Dr. mcHugh completed her certification in Manual Therapy and Trigger Point Dry Needling, as well as Kineseotaping. This author has the following disclosures:

Research SupportOrokawa Foundation

Ashley Miller, PT, DPTKennedy Krieger Institute Bio:Dr. Miller is certified in Kinesiotaping I-IV, am a certified Walk-Aide Clinician, and has completed Clinical Education Internship Instruction for a full-time Doctorate of Physical Therapy candidate during the summer of 2015. Her research interests are in transcutaneous spinal cord stimulation (TSCS) and electrical stimulation (ES). Dr. Miller's current research projects include (1) the use of TSCS on motor complete and incomplete SCI to determine differences in walking function and voluntary LE motor function and (2) facilitation of voluntary motor activation utilizing transcutaneous electrical spinal cord stimulation. She has presented research via posters and presentations at the American Spinal Cord Injury Association 2016 and 2017 Annual Meeting and the Spinal Cord Symposium at Kennedy Krieger Institute.

Education:Dr. Miller received her Bachelors of Science in Exercise Science and Allied Professions from The University of Dayton and her Doctorate of Physical Therapy from Washington University in St Louis. Dr. Miller joined The Kennedy Krieger Institute in 2013 as a Physical Therapist in the International Center for Spinal Cord Injury. This author has the following disclosures:

Research SupportOrokawa Foundation

77Alternative ways to exercise after SCI- Overground cycling with electrical stimulation without motor assistance- Case StudyThursday, May 03, 2018 07:00 AM - 08:00 AMLearning Objectives:Learning Objectives: 1. Describe an alternative way to exercise with stimulation-driven cycling using a modified recumbent trike to allow stationary and over-ground pedaling without motor assistance. 2. Describe preliminary results of a training protocol utilized with 2 individuals with SCI.

Participants:1Lombardo L, 1Foglyano K, 1Bailey S, 1Triolo R, 2McDaniel J1Louis Stokes Cleveland Va Medical Center , Clevleland , Ohio, USA; 2Kent State University , Kent , Ohio, USALisa Lombardo, MPTLouis Stokes Cleveland Va Medical Center Bio:Lisa Lombardo, MPT is a Research Clinical Coordinator at the Louis Stokes Cleveland VAMC. Lisa received her Bachelor of Science Degree from the Ohio State University in 1994. She is a graduate of Slippery Rock University’s Master of Physical Therapy program in 1997. Lisa began her career at the Cleveland Clinic Foundation where she gained extensive experience in neuro rehab, pediatrics, acute care, and subacute care. She was the Center Coordinator of Clinical

Education and hosted numerous continuing education classes for staff. In 2003 she moved to Minnesota and was a senior therapist at the Courage Center where she gained extensive experience working with individuals with spinal cord injury and brain injury. She was adjunct professor for St Catherine University in St. Paul. Lisa specializes in the treatment of individuals with spinal cord injury, stroke and multiple sclerosis. She is certified in NDT. She is currently involved in several research projects involving the use of an implanted neuroprothesis and electrical stimulation to provide individuals with paralysis the ability to regain functions such as standing, stepping and seated stability. Lisa is also currently a part time professor in the Department of Health Sciences at Cleveland State University. She has presented the research outcomes and courses on functional electrical stimulation numerous times at conferences. Lisa is a member of International Functional Electrical Stimulation Society. She is co-author of 14 publications in various journals and over 40 posters and abstracts. Education:B.S. in Psycohology- The Ohio State University 1989-1994 Master's in Physical Therapy- Slippery Rock University 1994-1997This author has no relevant disclosures.Kevin Foglyano, BMELouis Stokes Cleveland Va Medical Center This author has no relevant disclosures.Stephanie Bailey, BMELouis Stokes Cleveland Va Medical Center This author has no relevant disclosures.Ronald Triolo, PhDLouis Stokes Cleveland Va Medical Center This author has no relevant disclosures.John McDaniel, PhDKent State University This author has no relevant disclosures.

78Epidural spinal cord stimulation affects bladder and bowel function – A Case reportThursday, May 03, 2018 07:00 AM - 08:00 AMLearning Objectives:To provide pilot data regarding the effect of acute epidural spinal cord stimulation on bladder and bowel function in individuals with spinal cord injury.

Participants:1Walter M, 1Lee A, 2Kavanagh A, 3Phillips A, 1Krassioukov A1International Collaboration on Repair Discoveries (Icord), Faculty of Medicine, University of British Columbia , Vancouver , BC, Canada; 2Department of Urologic Sciences, Faculty of Medicine, University of British Columbia , Vancouver , BC, Canada; 3Physiology and

Pharmacology, Cumming School of Medicine, Libin Cardiovascular Institute, Hotchkiss Brain Institute, University of Calgary , Calgary , AB, CanadaMatthias Walter, MD, FEBUInternational Collaboration on Repair Discoveries (Icord), Faculty of Medicine, University of British Columbia Bio:Matthias Walter graduated in 2006 with a degree in medicine from the Friedrich-Schiller-University Jena, Germany. In 2014, he completed his MD thesis about the outcome and complications of intrathecal baclofen therapy in children at the University of Zurich. His residency included clinical training in General Surgery, Pediatric Surgery and Urology. Between December 2011 and 2014 he worked as a full-time PhD candidate at the Spinal Cord Injury Centre and Research, University of Zürich, Balgrist University Hospital, Zürich, Switzerland. He completed his residency in Urology and passed the board certification examination of the Swiss Association of Urology at the Cantonal Hospital Aarau in September 2016. He has been board certified as a Urologist by the Swiss Society of Urology and is a fellow of the European Board of Urology (FEBU). Since November 2016, he is a postdoctoral research fellow at the International Collaboration on Repair Discoveries (ICORD).Education:UNIVERSITY Friedrich Schiller University Jena, Germany / Medicine (M.D.) / 04/2006 University of Zurich, Switzerland / Doctorate in Medicine (Dr. med.) / 01/2014 / Pediatrics

RESIDENCY AND BOARD CERTIFICATION Cantonal Hospital Aarau, Switzerland / Urologist / 10/2016 / Residency Urology European Board of Urology / Fellow of the European Board of Urology (FEBU) / 10/2016 / Urology This author has the following disclosures:

Research Support2017 Michael Smith Foundation for Health Research (MSFHR) Trainee Award (Postdoctoral Research Fellowship) co-funded with Rick Hansen Institute (RHI). WellSpect Research "Grant-in-aid"Amanda Lee, BScInternational Collaboration on Repair Discoveries (Icord), Faculty of Medicine, University of British Columbia This author has the following disclosures:

Research SupportCanadian Institutes of Health Research (CIHR) Master Scholarship.Alex Kavanagh, PEng, MPH, MD, FRCSCDepartment of Urologic Sciences, Faculty of Medicine, University of British Columbia This author has no relevant disclosures.Aaron Phillips, PhDPhysiology and Pharmacology, Cumming School of Medicine, Libin Cardiovascular Institute, Hotchkiss Brain Institute, University of Calgary This author has no relevant disclosures.

Andrei Krassioukov, MD, PhD, FRCPCInternational Collaboration on Repair Discoveries (Icord), Faculty of Medicine, University of British Columbia This author has the following disclosures:

Research Support Other (see below)

ONGOING RESEARCH SUPPORT

1. Craig H. Neilsen Foundation QOL Project Grants. Title: Motherhood after spinal

cord injury: lactation, breastfeeding, and autonomic dysreflexia. Period: 2016-2017

ROLE: PI

2. Heart and Stroke GIA 2016/17. Title: When are blood vessels “ready to rupture”?

Cerebrovascular health following spinal cord injury: from animal models to clinical

practice. Period: 2016 – 2019

ROLE: PI

3. Pfizer Canada Inc. Title: A Phase II, Open-Label Exploratory Study Investigating the

Efficacy of Toviaz for Treatment of Adult Patients with Spinal Cord Injury (SCI) with

Neurogenic Detrusor Overactivity (NDO) for Amelioration of Autonomic Dysreflexia

(AD). Period: Nov 2015 –Feb 2017

ROLE: PI

4. Rick Hansen Institute. Title: Development of a mobile app (telephone/iPod

application) for emergency department physicians on recognition and management

of life-threatening episodes of autonomic dysreflexia: “ABC of AD for the EM doc”.

Period: Apr 2015-Dec 2016.

ROLE: PI

5. Vancouver Foundation. Title: Vancouver Foundation Start-up Funds: Period: April

2015 – March 2017

ROLE: PI

6. Christopher and Dana Reeve Foundation. Title: Big Idea Cardiovascular Committee.

Period: Feb 2015-Aug2015.

ROLE: PI

7. Rick Hansen Institute/ RHI Pilot Studies - Optimizing Neurorecovery Following SCI.

Title: Effect of epidural stimulation on cardiovascular control following spinal cord

injury. Period: Mar 2015-Mar 2017.

ROLE: PI

8. Rick Hansen Foundation/International Collaboration On Repair Discoveries

(ICORD)/Seed Grants. Title: Development of evidence-based guidelines for blood

pressure management during iatrogenically-induced autonomic dysreflexia in those

with spinal cord injury: the limits of cerebral autoregulation. Period: Apr 2014-Jun

2016.

PI: Dr. Stacy Elliott.

ROLE: Co-Investigator

9. Department of Defense USA. Title: Alleviating autonomic dysreflexia after spinal

cord injury. Period: September 2014-August 2017.

ROLE: PI

10. Craig H. Neilsen Foundation/ Neilsen Senior Research Grant. Title: Cardiac

function after spinal cord injury: from bench to bedside. Period: July 2013-June 2017.

ROLE: PI

11. Rick Hansen Institute. Title: Validation of the International Autonomic Standards

for evaluation of individuals with chronic spinal cord injury. Period: March 2013-

March 2017.

ROLE: PI

12. Rick Hansen Foundation. Title: Improving Cardiovascular Health for Canadians

Living with SCI: Effects of Exercise, sex Differences, and Targeted Clinical Education.

Period: April 2012-March 2017.

ROLE: PI

13. Rick Hansen Institute / Operating Grant. Title: BOTOX treatment for neurogenic

detrusor hyperreflexia and prevention of autonomic dysreflexia following spinal cord

injury. Period: July 2012 – Jan. 2017.

ROLE: PI

14. Canadian Institutes of Health Research (CIHR) / Chronic disease risk and

intervention strategies team grant. Title: Improving cardiovascular health for

Canadians living with spinal cord injury: effects of exercise and targeted education.

Period: Dec. 2011-Nov. 2016.

ROLE: PI

15. Craig H. Neilsen Foundation/Christopher and Dana Reeve Foundation. Title:

Recovery of cardiovascular function with epidural stimulation after human spinal

cord injury. Period: January 2015-December 2017.

PI: Dr. Susan Harkema

ROLE: Co-Investigator

16. Canadian Institutes of Health Research (CIHR) / Operating grant. Title: Beyond

VO2peak: Understanding exercise-induced changes in cardiovascular function after

stroke. Period: 2011-2015.

PI: Dr. J. Eng

ROLE: Co-Investigator

17. International Spinal Research Trust / Operating grant. Title: Peripheral

Sympathetic and sensory plasticity in bladder and bowel circuitry in chronic spinal

cord injury. Period: Jan. 2011-Aug. 2014.

PI: Dr. M. Ramer

ROLE: Co-Investigator

18. Rick Hansen Institute Start Up Funds. Title: Rick Hansen Institute Start-Up Funds.

Period: March 2007 – March 2020.

ROLE: PI

OTHER

Coloplast and WellSpect

79Case reports on utilizing a ketogenic diet to improve neuro-recovery and metabolism following spinal cord injury (SCI)Thursday, May 03, 2018 07:00 AM - 08:00 AMLearning Objectives:- Review series of patients either received a KD or SD and their subsequent changes in neurological function, fasting glucose, fasting insulin and gut microbiome composition. - Discuss what is currently known regarding neural plasticity after SCI. - Discuss current treatment options in the acute and sub-acute period after traumatic SCI. - Discuss the proposed mechanisms by which a KD may offer protection following a traumatic SCI. - Discuss areas of future research that are needed.

Participants:Aslam H, Renfro C, Bosarge P, Kulkani A, Cetin H, Cetin B, Kirksey K, McLain A, Yarar-Fisher CUniversity of Alabama at Birmingham , Birmingham , Alabama, USAHammad Aslam, MDUniversity of Alabama at Birmingham Bio:Dr. Aslam is a Resident Physician who joined the UAB Department of Physical Medicine and Rehabilitation in 2015. After he graduated from the University of Georgia with a degree in Chemistry in 2008, he was in an automobile accident in 2009 that resulted in his incurring a traumatic brain injury, a C5 brachial plexus injury and a T3 spinal cord injury. In 2014, he earned his MD from the Medical College of Georgia at Augusta University, where he also completed an internship in Internal Medicine in 2015. Dr. Aslam is member of American Academy of Physical Medicine and Rehabilitation, Academy of Spinal Cord Injury Professionals and serves on the Junior Board for Lakeshore Foundation, a 501(c)3 non-profit organization which serves people with physical disabilities.Education:University of Georgia, 2005-2008, Chemistry. Medical College of Georgia, 2010-2014, MD.

Medical College of Georgia, Internship, 2014-2015. University of Alabama at Birmingham, PM&R Residency, 2015-2018.This author has no relevant disclosures.Cassandra Renfro, DOUniversity of Alabama at Birmingham This author has no relevant disclosures.Patrick Bosarge, MDUniversity of Alabama at Birmingham This author has no relevant disclosures.Adarsh Kulkani, University of Alabama at Birmingham This author has no relevant disclosures.Hatice Cetin, PT, MScUniversity of Alabama at Birmingham This author has no relevant disclosures.Baris Cetin, PT, MScUniversity of Alabama at Birmingham This author has no relevant disclosures.Keneshia Kirksey, MDUniversity of Alabama at Birmingham This author has no relevant disclosures.Amie McLain, MDUniversity of Alabama at Birmingham This author has no relevant disclosures.Ceren Yarar-Fisher, PT, PhDUniversity of Alabama at Birmingham This author has no relevant disclosures.

80Problem solving and social support patterns among family caregivers of adults with SCIThursday, May 03, 2018 08:00 AM - 09:30 AMLearning Objectives:Differentiate caregivers based on social support and problem solving and how both impact caregiver wellbeing.

Participants:1O'Rourke K, 1Kelly E, 1January A, 2Ghaffari A, 3Harris G, 2Richardson M, 4Chen D, 5Ray L1Shriners Hospitals for Children Chicago , Chicago , IL, USA; 2Hines Veteran Administration , Hines , IL, USA; 3Marquette University , Milwaukee , Wisconsin, United states; 4Shirley Ryan Abilitylab , Chicago , IL, USA; 5Schwab Rehabilitation Hospital , Chicago , IL, USAKerry O'Rourke, MPH, MAShriners Hospitals for Children Chicago

This author has the following disclosures: Research Support

Marquette University, Shriners Hospitals for Children ChicagoErin Kelly, PhDShriners Hospitals for Children Chicago This author has the following disclosures:

Consultant Other (see below)

Scientific Staff and Consultant at Shriners Hospitals for Children Chicago; Staff at American Academy of PediatricsAli January, PhDShriners Hospitals for Children Chicago This author has the following disclosures:

Research SupportShriners Hospitals for Children ChicagoAzadeh Ghaffari, PhDHines Veteran Administration This author has the following disclosures:

Other (see below)Staff, Hines VAGerald Harris, PhDMarquette University This author has the following disclosures:

Research Support Other (see below)

Faculty at Marquette University, Shriners Hospitals for Children ChicagoMichael Richardson, MDHines Veteran Administration This author has the following disclosures:

Other (see below)Staff, Hines VADavid Chen, MDShirley Ryan Abilitylab This author has the following disclosures:

Other (see below)Staff, Shirley Ryan AbilityLab, ChicagoLee Ray, MDSchwab Rehabilitation Hospital This author has the following disclosures:

Other (see below)Staff, Schwab Rehabilitation Hospital, Chicago

8112-Month Safety and Efficacy Results from the SCiStar Study – A Phase 1/2a Trial of Human Embryonic Stem Cell-Derived Oligodendrocyte Progenitor Cells (AST-OPC1) in Patients with Subacute Cervical Spinal Cord InjuryThursday, May 03, 2018 08:00 AM - 09:30 AMLearning Objectives:Learning Objectives: Discuss the study design, safety and efficacy results of an open label trial that is evaluating an investigational cell-based therapy for subacute SCI.

Participants:1Wirth III E, 2Fessler R, 3Leslie D, 4Steinberg G, 5McKenna S, 6Liu C, 7Kurpad S, 1Chen S, 1Lebkowski J1Asterias Biotherapeutics , Fremont , CA, United states; 2Rush University , Chicago , IL, United states; 3Shepherd Center , Atlanta , GA, United states; 4Stanford University , Stanford , CA, United states; 5Santa Clara Valley Medical Center , San Jose , CA, United states; 6Usc Keck Medical Center , Los Angeles , CA, United states; 7Medical College of Wisconsin , Milwaukee , WI, United statesEdward Wirth III, MD, PhDAsterias Biotherapeutics Bio:Edward D. Wirth, III, M.D., Ph.D., joined Asterias Biotherapeutics as Chief Translational Officer in 2013 and has served as the Chief Medical Officer since 2015. Prior to that Dr. Wirth served as Chief Science Officer at InVivo Therapeutics Corporation from 2011 to 2012. From 2004 to 2011, Dr. Wirth served as Medical Director for Regenerative Medicine at Geron Corporation. Dr. Wirth held academic appointments at Rush-Presbyterian St. Luke's Medical Center and at the University of Chicago from 2002 to 2004, and was a member of the faculty of the University of Florida from 1996 to 2002. Dr. Wirth received his Ph.D. and M.D. from the University of Florida in 1992 and 1994, respectively, and completed his B.A. degree in Physics at Rollins College in 1986.Education:Rollins College (Winter Park, FL), BA 1982-1986 Physics University of Florida (Gainesville, FL) PhD 1988-1992 Neuroscience University of Florida (Gainesville, FL) MD 1986-1988, 1992-1994 MedicineThis author has the following disclosures:

Shareholder Other (see below)

Employee of AsteriasRichard Fessler, MD, PhDRush University This author has no relevant disclosures.Donald Leslie, MDShepherd Center

This author has no relevant disclosures.Gary Steinberg, MD, PhDStanford University This author has no relevant disclosures.Stephen McKenna, MDSanta Clara Valley Medical Center This author has no relevant disclosures.Charles Liu, MD, PhDUsc Keck Medical Center This author has no relevant disclosures.Shekar Kurpad, MD, PhDMedical College of Wisconsin This author has no relevant disclosures.Susy Chen, MDAsterias Biotherapeutics This author has the following disclosures:

Shareholder Other (see below)

Employee of AsteriasJane Lebkowski, PhDAsterias Biotherapeutics This author has the following disclosures:

Shareholder Other (see below)

Employee of Asterias

82Zest: Promoting Psychological Health of Women with SCI in the Virtual World of Second LifeThursday, May 03, 2018 08:00 AM - 09:30 AMLearning Objectives:Learning Objective 1: Summarize participant feedback and response to the feasibility test of the intervention program. Learning Objective 2: Describe the development of Zest to be used in a randomized controlled trial.

Participants:1Robinson-Whelen S, 2Hughes R, 3Taylor H, 3Markley R, 3Vega J, 1Nosek M1Tirr Memorial Hermann / Baylor College of Medicine , Houston , TX, USA; 2University of Montana , Missoula , MT, USA; 3Tirr Memorial Hermann , Houston , TX, USASusan Robinson-Whelen, PhDTirr Memorial Hermann / Baylor College of Medicine

Bio:Susan Robinson-Whelen, Ph.D. holds appointments as Scientist at the Spinal Cord Injury and Disability Research Center (SCIDR) at TIRR Memorial Hermann, Senior Investigator at the Center for Research on Women with Disabilities (CROWD), and Assistant Professor in the Department of Physical Medicine and Rehabilitation at Baylor College of Medicine. Her research focuses on the health and well-being of people with disabilities. She has been involved in numerous studies that have developed and tested the efficacy of interventions designed to address the unique needs of women with disabilities, including interventions focused on health promotion, weight management, safety awareness and abuse prevention, depression self-management, stress self-management, and self-esteem enhancement for women with disabilities. Education:Louisiana State University (Baton Rouge, LA) BS 1984, Psychology

Washington University in St. Louis (St. Louis, MO) MA, 1987-1989, Clinical Psychology

Vanderbilt University and Nashville VA Consortium (Nashville, TN) 1992-1993, Clinical Psychology/Geropsychology,

Washington University in St. Louis (St. Louis, MO) PhD, 1993, Clinical Psychology/Geropsychology

Ohio State University, Department of Psychiatry (Columbus, OH) 1993-1995, Postdoctoral Fellowship, Health Psychology

This author has the following disclosures: Research Support

Investigator on studies funded by NIDILRR and Craig H. Neilsen FoundationRosemary Hughes, PhDUniversity of Montana This author has the following disclosures:

Research SupportInvestigator on studies funded by NIDILRR, NIH/NICHD, and Craig H. Neilsen FoundationHeather Taylor, PhDTirr Memorial Hermann This author has the following disclosures:

Research SupportInvestigator on studies funded by NIDILRR and Craig H. Neilsen FoundationRachel Markley, MPHTirr Memorial Hermann This author has the following disclosures:

Research SupportResearch assistant funded by studies from NIDILRR and Craig H. Neilsen Foundation

Jose Vega, BSTirr Memorial Hermann This author has the following disclosures:

Research SupportResearch assistant funded by studies from NIDILRR and Craig H. Neilsen FoundationMargaret Nosek, PhDTirr Memorial Hermann / Baylor College of Medicine This author has the following disclosures:

Research SupportInvestigator on studies funded by NIDILRR and Craig H. Neilsen Foundation

83A New Distributed Neuroprosthesis Enables Hand Grasp and Trunk Posture after Cervical Spinal Cord InjuryThursday, May 03, 2018 08:00 AM - 09:30 AMLearning Objectives:1. Understand the basic operating principles of implanted neuroprostheses. 2. Recognize the expected outcomes for neuroprostheses as implemented for upper extremity and trunk function. 3. Be able to recognize the individuals who are candidates for this type of intervention.

Participants:1Kilgore K, 1Hoyen H, 1Keith M, 2Triolo R, 3Bryden A, 2Lombardo L, 2Hart R, 2Miller M, 1Nemunaitis G, 3Peckham P1Metrohealth Medical Center , Cleveland , OH, United states; 2Louis Stokes Cleveland Department of Veterans Affairs , Cleveland , OH, USA; 3Case Western Reserve University , Cleveland , OH, USAKevin Kilgore, PhDMetrohealth Medical Center Bio:Kevin L. Kilgore, Ph.D., received the BS degree in Biomedical Engineering from the University of Iowa, Iowa City, in 1983, and the MS and Ph.D. degrees in Biomedical Engineering from Case Western Reserve University, Cleveland, in 1987 and 1991. He is currently Professor, Department of Orthopaedics at MetroHealth Medical Center and School of Medicine, Case Western Reserve University. He is also a Biomedical Engineer in the Research Service of the Louis Stokes Cleveland Veterans Affairs Medical Center and is an Associate Director in the Cleveland Functional Electrical Stimulation Center. His research interests are in the clinical applications of functional electrical stimulation to provide hand and arm function for individuals with paralysis, and in the application of electrical currents to control unwanted neural activity.Education:University of Iowa (Iowa City, IA), BS 1979-1983 Biomedical Engineering

Case Western Reserve University (Cleveland, OH), MS 1983-1987 Biomedical Engineering

Case Western Reserve University (Cleveland, OH), PhD 1987-1991 Biomedical EngineeringThis author has no relevant disclosures.Harry Hoyen, MDMetrohealth Medical Center This author has no relevant disclosures.Michael Keith, MDMetrohealth Medical Center This author has no relevant disclosures.Ronald Triolo, PhDLouis Stokes Cleveland Department of Veterans Affairs This author has no relevant disclosures.Anne Bryden, OTR/L, MACase Western Reserve University This author has no relevant disclosures.Lisa Lombardo, PTLouis Stokes Cleveland Department of Veterans Affairs This author has no relevant disclosures.Ronald Hart, MSLouis Stokes Cleveland Department of Veterans Affairs This author has no relevant disclosures.Michael Miller, MSLouis Stokes Cleveland Department of Veterans Affairs This author has no relevant disclosures.Gregory Nemunaitis, MDMetrohealth Medical Center This author has no relevant disclosures.P Peckham, PhDCase Western Reserve University This author has no relevant disclosures.

84Feasibility and effectiveness of delivering an adapted weight loss intervention for people with spinal cord injuryThursday, May 03, 2018 08:00 AM - 09:30 AMLearning Objectives:1. Describe features of the GLB AIM that uniquely address issues lifestyle change issues around dietary change and physical activity among those with SCI.

2. Describe feasibility and effectiveness outcomes on weight loss of the GLB AIM among those with SCI.

Participants:1Driver S, 2Kramer K, 3Lee J, 1Froehlich-Grobe K1Baylor Institute for Rehabilitation , Dallas , TX, USA; 2Innovative Wellness Solutions , Pittsburgh , PA, USA; 3Texas Tech University , Lubbock , TX, USASimon Driver, PhDBaylor Institute for Rehabilitation This author has no relevant disclosures.Kaye Kramer, DrPH, MPH, RNInnovative Wellness Solutions This author has no relevant disclosures.Jaehoon Lee, PhDTexas Tech University This author has no relevant disclosures.Katherine Froehlich-Grobe, PhDBaylor Institute for Rehabilitation Bio:Dr. Froehlich-Grobe is Associate Director of Research at Baylor Institute for Rehabilitation. Dr. Froehlich-Grobe received her undergraduate degree from the George Washington University, with a double major in American Literature and Psychology and completed her graduate training the University of Kansas, earning both a Master’s and Doctoral degrees in the Department of Applied Behavioral Science. Dr. Grobe’s research program has focused on exploring and promoting the health and function of individuals with physical disabilities, including spinal cord injury. She has received funding from CDC, NIH, and NIDILRR. Her research program focuses on promoting health, function, and participation among those with disabilities and she has conducted several funded studies that have examined theory-based approaches to promoting physical activity and also weight loss with heterogeneous samples of individuals with physical disabilities, including spinal cord injury. Education:PhD Applied Behavioral Sciences, University of Kansas, Lawrence, KS 2001

MA Applied Behavioral Sciences, University of Kansas, Lawrence, KS 1994

BA Psychology and American Literature, George Washington University, Washington DC

This author has the following disclosures:

85Combined Regenerative and Rehabilitative Approach to Promote Autonomic Recovery after Spinal Cord InjuryThursday, May 03, 2018 08:00 AM - 09:30 AMLearning Objectives:Discuss the cardio-autonomic consequences of spinal cord injury as well as the therapeutic potential of regenerative and rehabilitative approaches using a well-characterized animal model.

Participants:Sachdeva R, Sangha A, Auyeung A, Hutton G, Gopaul R, Ramer M, Krassioukov AUniversity of British Columbia , Vancouver , BC, CanadaRahul Sachdeva, PhDUniversity of British Columbia Bio:Rahul Sachdeva, PhD, is a Craig H. Neilsen Postdoctoral Fellow at the International Collaboration on Repair Discoveries (ICORD, University of British Columbia) in the laboratory of Dr. Andrei Krassioukov. After completing a Bachelors degree in Biotechnology at Pd. Dr. D. Y Patil University, Navi Mumbai, India with a University Gold Medal in 2010, Dr. Sachdeva earned a doctorate in Neuroscience in the laboratory of Dr. John Houle at Drexel University, Philadelphia (2010-15). With research experience spanning across various disciplines ranging from cellular, and molecular biology to microanatomy and physiology, Dr. Sachdeva has been trained on the rat model of spinal cord injury (SCI) focusing on multiple strategies to improve regeneration from spinal cord after injury. After Joining Dr. Krassioukov’s laboratory, Dr. Sachdeva has employed nerve regeneration strategies to promote cardio-autonomic recovery, which is among the highest priorities for recovery after SCI. This study has been recently funded by a two-year postdoctoral fellowship from Craig Neilsen Foundation. In addition to testing potential therapeutic strategies, Dr. Sachdeva is interested in understanding the SCI-associated plasticity in both central and peripheral autonomic neurons that lead to autonomic deficits. Education:Pd. Dr. D. Y. Patil University (Navi Mumbai, India)/ B. Tech./ 2005-09/ Biotechnology Drexel University College of Medicine (Philadelphia, USA)/ Ph.D./ 2010-15/ Neuroscience University of British Columbia, International Collaboration on Repair Discoveries (Vancouver, Canada) / Postdoctoral Fellow / 2015- present / Spinal Cord Injury-Autonomic function This author has the following disclosures:

Research SupportOngoing Research Support 2017/8 - 2019/7: Principal Applicant: Regenerative Strategies for Autonomic Recovery After Spinal Cord Injury. Craig H. Neilsen Foundation. Total Funding - 150,000 (United States dollar).

2016/10 - 2017/10: Co-applicant: ICORD Seed Grant- Combined neuroprosthetic and neuroprotective approach to promote restoration and recovery of autonomic circuitry. International Collaboration on Repair Discoveries. Total Funding - 20,000 (Canadian dollar). Arjun Sangha, BSUniversity of British Columbia This author has no relevant disclosures.Ariana Auyeung, University of British Columbia This author has no relevant disclosures.Gillian Hutton, University of British Columbia

This author has no relevant disclosures.Rayshad Gopaul, University of British Columbia This author has the following disclosures:Matt Ramer, PhDUniversity of British Columbia This author has no relevant disclosures.Andrei Krassioukov, University of British Columbia This author has the following disclosures:

Research Support Other (see below)

ONGOING RESEARCH SUPPORT 1. Craig H. Neilsen Foundation QOL Project Grants. Title: Motherhood after spinal cord injury: lactation, breastfeeding, and autonomic dysreflexia. Period: 2016-2017 ROLE: PI

2. Heart and Stroke GIA 2016/17. Title: When are blood vessels “ready to rupture”? Cerebrovascular health following spinal cord injury: from animal models to clinical practice. Period: 2016 – 2019 ROLE: PI

3. Pfizer Canada Inc. Title: A Phase II, Open-Label Exploratory Study Investigating the Efficacy of Toviaz for Treatment of Adult Patients with Spinal Cord Injury (SCI) with Neurogenic Detrusor Overactivity (NDO) for Amelioration of Autonomic Dysreflexia (AD). Period: Nov 2015 –Feb 2017 ROLE: PI

4. Rick Hansen Institute. Title: Development of a mobile app (telephone/iPod application) for emergency department physicians on recognition and management of life-threatening episodes of autonomic dysreflexia: “ABC of AD for the EM doc”. Period: Apr 2015-Dec 2016. ROLE: PI

5. Vancouver Foundation. Title: Vancouver Foundation Start-up Funds: Period: April 2015 – March 2017 ROLE: PI

6. Christopher and Dana Reeve Foundation. Title: Big Idea Cardiovascular Committee. Period: Feb 2015-Aug2015. ROLE: PI

7. Rick Hansen Institute/ RHI Pilot Studies - Optimizing Neurorecovery Following SCI. Title: Effect of epidural stimulation on cardiovascular control following spinal cord injury. Period: Mar 2015-Mar 2017.

ROLE: PI

8. Rick Hansen Foundation/International Collaboration On Repair Discoveries (ICORD)/Seed Grants. Title: Development of evidence-based guidelines for blood pressure management during iatrogenically-induced autonomic dysreflexia in those with spinal cord injury: the limits of cerebral autoregulation. Period: Apr 2014-Jun 2016. PI: Dr. Stacy Elliott. ROLE: Co-Investigator

9. Department of Defense USA. Title: Alleviating autonomic dysreflexia after spinal cord injury. Period: September 2014-August 2017. ROLE: PI

10. Craig H. Neilsen Foundation/ Neilsen Senior Research Grant. Title: Cardiac function after spinal cord injury: from bench to bedside. Period: July 2013-June 2017. ROLE: PI 11. Rick Hansen Institute. Title: Validation of the International Autonomic Standards for evaluation of individuals with chronic spinal cord injury. Period: March 2013- March 2017. ROLE: PI

12. Rick Hansen Foundation. Title: Improving Cardiovascular Health for Canadians Living with SCI: Effects of Exercise, sex Differences, and Targeted Clinical Education. Period: April 2012-March 2017. ROLE: PI

13. Rick Hansen Institute / Operating Grant. Title: BOTOX treatment for neurogenic detrusor hyperreflexia and prevention of autonomic dysreflexia following spinal cord injury. Period: July 2012 – Jan. 2017. ROLE: PI

14. Canadian Institutes of Health Research (CIHR) / Chronic disease risk and intervention strategies team grant. Title: Improving cardiovascular health for Canadians living with spinal cord injury: effects of exercise and targeted education. Period: Dec. 2011-Nov. 2016. ROLE: PI

15. Craig H. Neilsen Foundation/Christopher and Dana Reeve Foundation. Title: Recovery of cardiovascular function with epidural stimulation after human spinal cord injury. Period: January 2015-December 2017. PI: Dr. Susan Harkema ROLE: Co-Investigator

16. Canadian Institutes of Health Research (CIHR) / Operating grant. Title: Beyond VO2peak: Understanding exercise-induced changes in cardiovascular function after

stroke. Period: 2011-2015. PI: Dr. J. Eng ROLE: Co-Investigator

17. International Spinal Research Trust / Operating grant. Title: Peripheral Sympathetic and sensory plasticity in bladder and bowel circuitry in chronic spinal cord injury. Period: Jan. 2011-Aug. 2014. PI: Dr. M. Ramer ROLE: Co-Investigator

18. Rick Hansen Institute Start Up Funds. Title: Rick Hansen Institute Start-Up Funds. Period: March 2007 – March 2020. ROLE: PI

OTHER

Coloplast and WellSpect

86Opioid utilization in persons with and without spinal cord injury: A propensity-score matched comparison of opioid users in a privately insured population Thursday, May 03, 2018 09:30 AM - 10:30 AMLearning Objectives:Attendees will describe differences in opioid prescription patterns for persons with and without spinal cord injury.

Participants:Hand B, Krause J, Simpson KMedical University of South Carolina , Charleston , South caro, USABrittany Hand, PhD, OTR/LMedical University of South Carolina Bio:Brittany N. Hand, PhD, OTR/L is a Postdoctoral Scholar at the Medical University of South Carolina. After receiving her Bachelor’s degree in biology and Master’s degree in occupational therapy from The Ohio State University, Dr. Hand went on to earn her PhD in Health and Rehabilitation Science, with a focus on data analytics, from The Ohio State University in 2016. She is now working as a Postdoctoral Scholar funded by the South Carolina Spinal Cord Injury Research Fund. In this role, Dr. Hand focuses on health services research and longitudinal health outcomes in the spinal cord injured population. To date, a majority of her postdoctoral work has centered on: 1) the development of valid and reliable patient reported outcome measures related to pain and pain medication use and 2) population-based analyses of medication prescription patterns in persons with spinal cord injury. Education:The Ohio State University (Columbus, OH), BS in Biology, 2007-2011

The Ohio State University (Columbus, OH), Master’s in Occupational Therapy, 2011-2013 The Ohio State University (Columbus, OH), PhD in Health and Rehabilitation Sciences, 2013-2016This author has no relevant disclosures.James Krause, PhDMedical University of South Carolina This author has no relevant disclosures.Kit Simpson, DrPHMedical University of South Carolina This author has no relevant disclosures.

87Incidence of adverse drug events with polypharmacy differs between persons with and without spinal cord injury Thursday, May 03, 2018 09:30 AM - 10:30 AMLearning Objectives:Attendees will compare the incidence and frequency of adverse drug events among persons with polypharmacy with and without spinal cord injury.

Participants:Hand B, Krause J, Simpson KMedical University of South Carolina , Charleston , SC, USABrittany Hand, PhD, OTR/LMedical University of South Carolina Bio:Brittany N. Hand, PhD, OTR/L is a Postdoctoral Scholar at the Medical University of South Carolina. After receiving her Bachelor’s degree in biology and Master’s degree in occupational therapy from The Ohio State University, Dr. Hand went on to earn her PhD in Health and Rehabilitation Science, with a focus on data analytics, from The Ohio State University in 2016. She is now working as a Postdoctoral Scholar funded by the South Carolina Spinal Cord Injury Research Fund. In this role, Dr. Hand focuses on health services research and longitudinal health outcomes in the spinal cord injured population. To date, a majority of her postdoctoral work has centered on: 1) the development of valid and reliable patient reported outcome measures related to pain and pain medication use and 2) population-based analyses of medication prescription patterns in persons with spinal cord injury. Education:The Ohio State University (Columbus, OH), BS in Biology, 2007-2011 The Ohio State University (Columbus, OH), Master’s in Occupational Therapy, 2011-2013 The Ohio State University (Columbus, OH), PhD in Health and Rehabilitation Sciences, 2013-2016 This author has no relevant disclosures.James Krause, PhDMedical University of South Carolina

This author has no relevant disclosures.Kit Simpson, DrPHMedical University of South Carolina This author has no relevant disclosures.

88Correlating chronic pelvic and hip pressure injuries and bilateral hip destruction due to osteomyelitis: a case seriesThursday, May 03, 2018 09:30 AM - 10:30 AMLearning Objectives:-Review the correlation between pressure injuries and osteomyelitis in individuals with SCI, including etiology, clinical presentation, risk factors, diagnosis, and treatment.

Participants:1Yurkiewicz S, 2Shem K1Stanford University , Redwood City , Ca- califo, U.S.; 2Santa Clara Valley Medical Center , San Jose , Ca- califo, U.S.Shara Yurkiewicz, MDStanford University Bio:Shara Yurkiewicz, MD, is a second-year resident in physical medicine and rehabilitation at Stanford University in Redwood City, CA. She graduated from Harvard Medical School in 2014 and Yale University cum laude in 2009 with an intensive B.S. in biology and distinction in the major. Dr. Yurkiewicz has served as the AAPM&R Resident Physician Council Ambassador for Stanford. She has experience in medical journalism, working as a science reporter at the Los Angeles Times via the AAAS Mass Media Science and Engineering Fellowship and as MedPage Today’s inaugural Medical Journalism Fellow. She has written articles for outlets including Scientific American, the Public Library of Science, and Discover. Her pieces have been republished on National Public Radio, included in two Best Science Online writing anthologies, and featured as recommended reading in academic circles. She has made appearances on national public radio in the United States and Canada speaking on the medical training experience. She is a former guest editor for the AMA Journal of Ethics and a former editorial intern for the Hastings Center. Education:Stanford Health Care (Stanford, CA) 2016-present Residency, Physical Medicine and Rehabilitation

Overlook Medical Center (Summit, NJ) 2015-2016 Internship, Internal Medicine

Harvard Medical School (Boston, MA), MD, 2010-2014

Yale University (New Haven, CT), Intensive BS in Molecular, Cellular and Developmental Biology, Cum laude, Distinction in Biology Major, 2005-2009

This author has the following disclosures: Other (see below)

I am employed by Stanford University as a resident in physical medicine and rehabilitation.Kazuko Shem, MDSanta Clara Valley Medical Center This author has the following disclosures:

Research Support Other (see below)

Employed at SCVMC / County of Santa Clara.

Grant support currently with the Cria Neilsen Foundation.

89Cardiovascular Adaptations to Exercise Intervention in SCI populationThursday, May 03, 2018 09:30 AM - 10:30 AMLearning Objectives:1. Review cardiovascular health outcomes in the SCI population. Review key limitations and deterrents to exercise in the SCI population. Describe the cardiovascular effects of body weight support treadmill training and arm-cycle ergometry in individuals with chronic SCI.

Participants:1Shamatutu C, 1Gavric M, 2Currie K, 3Hubli M, 4MacDonald M, 1Krassioukov A1University of British Columbia; International Collaboration on Repair Discoveries , Vancouver , BC, Canada; 2Mcmaster University; Child Health and Exercise Medicine Program , Hailton , Ontario, Canada; 3University of Zurich; Spinal Cord Injury Centre , Zürich , , Switzerland; 4Mcmaster University; Ivor Wynne Centre , Hamilton , Ontario, CanadaChristopher Shamatutu, BSc.University of British Columbia; International Collaboration on Repair Discoveries Bio:Christopher N. Shamatutu, BSc, is a research assistant at the International Collaboration on Repair Discoveries (ICORD) with the Faculty of Medicine, University of British Columbia, and a second year medical student at the University of British Columbia. After receiving his Bachelor's Degree in Biological Sciences with a focus on neuroscience at the University of Alberta in 2016, Christopher went on to the University of British Columbia Medical School. He has research funding support from the University of British Columbia and the Mach-Gaensslen Foundation of Canada. He studies the cardiovascular, respiratory, metabolic, and psychological effects of exercise in humans after spinal cord injury. Education:University of British Columbia (Vancouver, British Columbia), MD 2016-2020 (expected)

University of Alberta (Edmonton, Alberta), BSc 2012-2016This author has no relevant disclosures.

Marko Gavric, B.KinUniversity of British Columbia; International Collaboration on Repair Discoveries This author has no relevant disclosures.Katharine Currie, PhDMcmaster University; Child Health and Exercise Medicine Program This author has no relevant disclosures.Michèle Hubli, PhDUniversity of Zurich; Spinal Cord Injury Centre This author has no relevant disclosures.Maureen MacDonald, PhDMcmaster University; Ivor Wynne Centre This author has no relevant disclosures.Andrei Krassioukov, MD, PhDUniversity of British Columbia; International Collaboration on Repair Discoveries This author has the following disclosures:

Research Support Other (see below)

ONGOING RESEARCH SUPPORT 1. Craig H. Neilsen Foundation QOL Project Grants. Title: Motherhood after spinal cord injury: lactation, breastfeeding, and autonomic dysreflexia. Period: 2016-2017 ROLE: PI

2. Heart and Stroke GIA 2016/17. Title: When are blood vessels “ready to rupture”? Cerebrovascular health following spinal cord injury: from animal models to clinical practice. Period: 2016 – 2019 ROLE: PI

3. Pfizer Canada Inc. Title: A Phase II, Open-Label Exploratory Study Investigating the Efficacy of Toviaz for Treatment of Adult Patients with Spinal Cord Injury (SCI) with Neurogenic Detrusor Overactivity (NDO) for Amelioration of Autonomic Dysreflexia (AD). Period: Nov 2015 –Feb 2017 ROLE: PI

4. Rick Hansen Institute. Title: Development of a mobile app (telephone/iPod application) for emergency department physicians on recognition and management of life-threatening episodes of autonomic dysreflexia: “ABC of AD for the EM doc”. Period: Apr 2015-Dec 2016. ROLE: PI

5. Vancouver Foundation. Title: Vancouver Foundation Start-up Funds: Period: April 2015 – March 2017 ROLE: PI

6. Christopher and Dana Reeve Foundation. Title: Big Idea Cardiovascular Committee. Period: Feb 2015-Aug2015.

ROLE: PI

7. Rick Hansen Institute/ RHI Pilot Studies - Optimizing Neurorecovery Following SCI. Title: Effect of epidural stimulation on cardiovascular control following spinal cord injury. Period: Mar 2015-Mar 2017. ROLE: PI

8. Rick Hansen Foundation/International Collaboration On Repair Discoveries (ICORD)/Seed Grants. Title: Development of evidence-based guidelines for blood pressure management during iatrogenically-induced autonomic dysreflexia in those with spinal cord injury: the limits of cerebral autoregulation. Period: Apr 2014-Jun 2016. PI: Dr. Stacy Elliott. ROLE: Co-Investigator

9. Department of Defense USA. Title: Alleviating autonomic dysreflexia after spinal cord injury. Period: September 2014-August 2017. ROLE: PI

10. Craig H. Neilsen Foundation/ Neilsen Senior Research Grant. Title: Cardiac function after spinal cord injury: from bench to bedside. Period: July 2013-June 2017. ROLE: PI 11. Rick Hansen Institute. Title: Validation of the International Autonomic Standards for evaluation of individuals with chronic spinal cord injury. Period: March 2013- March 2017. ROLE: PI

12. Rick Hansen Foundation. Title: Improving Cardiovascular Health for Canadians Living with SCI: Effects of Exercise, sex Differences, and Targeted Clinical Education. Period: April 2012-March 2017. ROLE: PI

13. Rick Hansen Institute / Operating Grant. Title: BOTOX treatment for neurogenic detrusor hyperreflexia and prevention of autonomic dysreflexia following spinal cord injury. Period: July 2012 – Jan. 2017. ROLE: PI

14. Canadian Institutes of Health Research (CIHR) / Chronic disease risk and intervention strategies team grant. Title: Improving cardiovascular health for Canadians living with spinal cord injury: effects of exercise and targeted education. Period: Dec. 2011-Nov. 2016. ROLE: PI

15. Craig H. Neilsen Foundation/Christopher and Dana Reeve Foundation. Title: Recovery of cardiovascular function with epidural stimulation after human spinal cord injury. Period: January 2015-December 2017.

PI: Dr. Susan Harkema ROLE: Co-Investigator

16. Canadian Institutes of Health Research (CIHR) / Operating grant. Title: Beyond VO2peak: Understanding exercise-induced changes in cardiovascular function after stroke. Period: 2011-2015. PI: Dr. J. Eng ROLE: Co-Investigator

17. International Spinal Research Trust / Operating grant. Title: Peripheral Sympathetic and sensory plasticity in bladder and bowel circuitry in chronic spinal cord injury. Period: Jan. 2011-Aug. 2014. PI: Dr. M. Ramer ROLE: Co-Investigator

18. Rick Hansen Institute Start Up Funds. Title: Rick Hansen Institute Start-Up Funds. Period: March 2007 – March 2020. ROLE: PI

OTHER

Coloplast and WellSpect

90Definitions of traumatic conus medullaris and cauda equinaThursday, May 03, 2018 09:30 AM - 10:30 AMLearning Objectives:To discuss the definition of the CMS and the CES and it relevance for future (clinical) research.

Participants:Brouwers ERadboud University Medical Center , Nijmegen , Gelderland, The netherlandsEveline Brouwers, MPA, PhD studentRadboud University Medical Center Bio:Eveline Brouwers is physician Assistant, department of neurosurgery at the Radboud University Medical Center in Nijmegen, the Netherlands. Besides her ward activities, she is a PhD student. Topic: traumatic spinal cord injuries with special interest in the Conus Medullaris and Cauda Equina. Education:Physiotherapy, Hogeschool Arnhem - Nijmegen (BS) 2003 - 2007

Physician Assistant, Hogeschool Arnhem en Nijmegen (MPA) 2010 - 2013

PhD student Radboud University Nijmegen, from 2016 This author has no relevant disclosures.

91Better Together! Cross Country Collaborations and Lessons Learned in the Development of a Spinal Cord Injury Program in a New Inpatient Rehabilitation Hospital Thursday, May 03, 2018 09:30 AM - 10:30 AMLearning Objectives:The participant will be able to describe challenges in a cross country collaboration as well as strategies used to overcome those challenges.

Participants:1Perera M, 2McClure I1California Rehabilitation Institute , Los Angeles , CA, USA; 2Kessler Institute for Rehabilitation , West Orange , NJ, USAManeshka Perera, MS, OTR/LCalifornia Rehabilitation Institute Bio:Maneshka A. Perera, MS, OTR/L is the therapy education coordinator at California Rehabilitation Institute in Century City, CA. She received her Bachelor’s degree in child & adolescent development with a minor in gerontology from California State University, Northridge followed by a Master’s degree in occupational therapy from Columbia University. Maneshka has worked with the spinal cord injury (SCI) population both at Mount Sinai Medical Center and Rusk Rehabilitation at NYU Langone Medical Center. Maneshka was on the board of directors for United Spinal’s NYC chapter. She was also an active member of Wheeling Forward, and in this capacity, co-developed a community based exercise program for individuals with SCI along with being an instructor for a continuing education workshop that highlights a sensorimotor technique to address neurological trunk weakness. In January 2016, Maneshka was amongst a select number of individuals who helped with the opening of California Rehabilitation Institute: a joint partnership between Cedars-Sinai, UCLA Health and Select Medical. She serves as the Chair for the SCI taskforce: an interdisciplinary team that is tasked with developing the SCI program at California Rehabilitation Institute and is also the Chair of the SCI program steering committee. Maneshka also volunteers with Triumph Foundation, an organization dedicated to assisting those with SCI in the Los Angeles community and lastly serves on the membership committee of the American Spinal Injury Association as well as on the finance committee of the Academy of Spinal Cord Injury Professionals. Education:California State University, Northridge (Northridge, CA), BA 2003-2007 Child & Adolescent Development, Minor in Gerontology

Columbia University (New York, NY) MS 2007-2009 Occupational Therapy This author has the following disclosures:

Other (see below)

Salaried employee of California Rehabilitation Institute Isa McClure, PT, MAPTKessler Institute for Rehabilitation Bio:Isa A. McClure, PT, MAPT is an Advanced Clinical Specialist in Physical Therapy at the Kessler Institute for Rehabilitation, in West Orange, NJ. After receiving her Bachelor’s degrees in biology from Springfield College in 1991, she earned her Bachelor's in Health Sciences and her Masters in Physical Therapy from Touro College. She has presented extensively at both the ASIA and ASCIP meetings and served as the Committee Chair for ASIA's Rehab Standards Committee. While serving as Chair, she participated in the creation of SkinStep, an e-learning module dedicated to the prevention and treatment of pressure injuries as well as the Guide to DME for individuals with SCI/D and a guide to choosing Rehabilitation facilities for patients and their families Education:Springfield College (Springfield, MA), BS 1987-1991 Biology Touro College (Dix Hills, NY), BS 1993-1996 Health Sciences Touro College (Dix Hills, NY), MA1993-1996 Physical Therapy This author has the following disclosures:

Other (see below)Salaried employee of Kessler Institute for Rehabilitation

92Effect of Interface Peak Pressures following the Fifth Spine Board ModificationThursday, May 03, 2018 09:30 AM - 10:30 AMLearning Objectives:To demonstrate significant reduction in interface pressures on the fifth modification of the standard spine board for better skin protection technique for acutely injured persons, especially following spinal cord injury.

Participants:1Wilson J, 2Sun H, 1Roach M, 1Nemunaitis G1Metrohealth , Cleveland , OH, USA; 2Case Western Reserve University , Cleveland , OH, USAJames Wilson, DOMetrohealth Bio:James Wilson, DO is a physiatrist currently in fellowship for Spinal Cord Injury Medicine at Case Western/MetroHealth/Cleveland Clinic/Cleveland VA. Education:Case Western Reserve University (MetroHealth), Cleveland, OH • Spinal Cord Injury Medicine Fellowship Temple University/MossRehab, Philadelphia, PA • Physical Medicine & Rehabilitation (PM&R) Residency (PGY2-4) • Chief Resident (PGY4)

Delaware County Memorial Hospital, CKHN, Drexel Hill, PA • Osteopathic Traditional Rotating Internship (PGY1) Philadelphia College of Osteopathic Medicine, Philadelphia, PA • Doctor of Osteopathic Medicine (D.O.) Clark University, Worcester, MA • Bachelor of Art (B.A.) • Major in Mathematics, Minors in Biology, Physics, Concentration in Computational Science • Summa Cum Laude with Highest Honors in MathematicsThis author has no relevant disclosures.Helen Sun, MDCase Western Reserve University This author has no relevant disclosures.Mary Jo Roach, PhDMetrohealth This author has no relevant disclosures.Greg Nemunaitis, MDMetrohealth This author has no relevant disclosures.

93Time-course of Cardiac Changes following Acute Spinal Cord InjuryThursday, May 03, 2018 09:30 AM - 10:30 AMLearning Objectives:To present the temporal changes in left ventricular function in individuals with acute and subacute SCI.

Participants:1Balthazaar S, 2Currie K, 1Gavric M, 1Krassioukov A1International Collaboration on Repair Discoveries (Icord), Faculty of Medicine, University of British Columbia , Vancouver , BC, Canada; 2Child Health & Exercise Medicine Program, Department of Pediatrics, Mcmaster University , Hamilton , Ontario, CanadaShane Balthazaar, BScKin, RDCSInternational Collaboration on Repair Discoveries (Icord), Faculty of Medicine, University of British Columbia Bio:Shane J.T. Balthazaar, BScKin, RDCS, is a Master of Science candidate at the International Collaboration On Repair Discoveries (ICORD), attending The University of British Columbia. His thesis is focused on the investigation of cardiovascular function after spinal cord injury (SCI) and the effects of exercise on the SCI population. Shane completed his undergraduate degree at McMaster University in Hamilton, Canada in 2011. Next he completed his echocardiography training and since 2013, has been working as a cardiac sonographer in the Department of Cardiology at Vancouver General and St. Paul’s Hospitals. For last two years, Shane has been an Instructor for the Cardiac Sonography courses at the British Columbia Institute of Technology

(BCIT) in Vancouver, Canada. Shane has also travelled to Guyana in 2016 and 2017 with other cardiology experts from around Canada to educate and assist clinicians with echocardiography protocols and collaborate in establishing a Cardiology Department at Georgetown Public Hospital.Education:McMaster University (Hamilton, Ontario, Canada), BScKin 2006-2011 Kinesiology Science

McMaster-Mohawk Institute for Applied Health Sciences (Hamilton, Ontario, Canada), RDCS 2012-2013 Diagnostic Cardiac Sonography

The University of British Columbia (Vancouver, British Columbia, Canada), MSc 2017-Present Experimental MedicineThis author has the following disclosures:

Research Support Other (see below)

This study is supported by the Craig H. Neilsen Foundation.

Employee of Vancouver Coastal Health, Providence Health Care, and the British Columbia Institute of Technology.

International Collaboration on Repair Discoveries (ICORD), Faculty of Medicine, University of British ColumbiaKatharine Currie, PhD, CEP, RKinChild Health & Exercise Medicine Program, Department of Pediatrics, Mcmaster University This author has the following disclosures:

Research Support Other (see below)

This study is supported by the Craig H. Neilsen Foundation.

Post doctoral fellow at McMaster University.

International Collaboration on Repair Discoveries (ICORD), Faculty of Medicine, University of British ColumbiaMarko Gavric, International Collaboration on Repair Discoveries (Icord), Faculty of Medicine, University of British Columbia This author has the following disclosures:

Research Support Other (see below)

This study is supported by the Craig H. Neilsen Foundation.

Clinical Research Coordinator at the International Collaboration on Repair Discoveries (ICORD), Faculty of Medicine, University of British Columbia

Andrei Krassioukov, MD, PhD, FRCPCInternational Collaboration on Repair Discoveries (Icord), Faculty of Medicine, University of British Columbia This author has the following disclosures:

Research Support Other (see below)

International Collaboration on Repair Discoveries (ICORD), Faculty of Medicine, University of British Columbia

ONGOING RESEARCH SUPPORT

1. Craig H. Neilsen Foundation QOL Project Grants. Title: Motherhood after spinal cord injury: lactation, breastfeeding, and autonomic dysreflexia. Period: 2016-2017 ROLE: PI

2. Heart and Stroke GIA 2016/17. Title: When are blood vessels “ready to rupture”? Cerebrovascular health following spinal cord injury: from animal models to clinical practice. Period: 2016 – 2019 ROLE: PI

3. Pfizer Canada Inc. Title: A Phase II, Open-Label Exploratory Study Investigating the Efficacy of Toviaz for Treatment of Adult Patients with Spinal Cord Injury (SCI) with Neurogenic Detrusor Overactivity (NDO) for Amelioration of Autonomic Dysreflexia (AD). Period: Nov 2015 –Feb 2017 ROLE: PI

4. Rick Hansen Institute. Title: Development of a mobile app (telephone/iPod application) for emergency department physicians on recognition and management of life-threatening episodes of autonomic dysreflexia: “ABC of AD for the EM doc”. Period: Apr 2015-Dec 2016. ROLE: PI

5. Vancouver Foundation. Title: Vancouver Foundation Start-up Funds: Period: April 2015 – March 2017 ROLE: PI

6. Christopher and Dana Reeve Foundation. Title: Big Idea Cardiovascular Committee. Period: Feb 2015-Aug 2015. ROLE: PI

7. Rick Hansen Institute/ RHI Pilot Studies - Optimizing Neurorecovery Following SCI. Title: Effect of epidural stimulation on cardiovascular control following spinal cord injury. Period: Mar 2015-Mar 2017. ROLE: PI

8. Rick Hansen Foundation/International Collaboration On Repair Discoveries (ICORD)/Seed Grants. Title: Development of evidence-based guidelines for blood pressure management during atrogenically-induced autonomic dysreflexia in those with spinal cord injury: the limits of cerebral autoregulation. Period: Apr 2014-Jun 2016. PI: Dr. Stacy Elliott. ROLE: Co-Investigator

9. Department of Defense USA. Title: Alleviating autonomic dysreflexia after spinal cord injury. Period: September 2014-August 2017. ROLE: PI

10. Craig H. Neilsen Foundation/ Neilsen Senior Research Grant. Title: Cardiac function after spinal cord injury: from bench to bedside. Period: July 2013-June 2017. ROLE: PI

11. Rick Hansen Institute. Title: Validation of the International Autonomic Standards for evaluation of individuals with chronic spinal cord injury. Period: March 2013-March 2017. ROLE: PI

12. Rick Hansen Foundation. Title: Improving Cardiovascular Health for Canadians Living with SCI: Effects of Exercise, sex Differences, and Targeted Clinical Education. Period: April 2012-March 2017. ROLE: PI

13. Rick Hansen Institute / Operating Grant. Title: BOTOX treatment for neurogenic detrusor hyperreflexia and prevention of autonomic dysreflexia following spinal cord injury. Period: July 2012 – Jan. 2017. ROLE: PI

14. Canadian Institutes of Health Research (CIHR) / Chronic disease risk and intervention strategies team grant. Title: Improving cardiovascular health for Canadians living with spinal cord injury: effects of exercise and targeted education. Period: Dec. 2011-Nov. 2016. ROLE: PI

15. Craig H. Neilsen Foundation/Christopher and Dana Reeve Foundation. Title: Recovery of cardiovascular function with epidural stimulation after human spinal cord injury. Period: January 2015-December 2017. PI: Dr. Susan Harkema ROLE: Co-Investigator

16. Canadian Institutes of Health Research (CIHR) / Operating grant. Title: Beyond VO2peak: Understanding exercise-induced changes in cardiovascular function after stroke. Period: 2011-2015. PI: Dr. J. Eng ROLE: Co-Investigator

17. International Spinal Research Trust / Operating grant. Title: Peripheral Sympathetic and sensory plasticity in bladder and bowel circuitry in chronic spinal cord injury. Period: Jan. 2011-Aug. 2014. PI: Dr. M. Ramer ROLE: Co-Investigator

18. Rick Hansen Institute Start Up Funds. Title: Rick Hansen Institute Start-Up Funds. Period: March 2007 – March 2020. ROLE: PI

OTHER Coloplast and WellSpect

94Targeting the thrombin receptor to improve recovery of function after spinal cord injuryThursday, May 03, 2018 09:30 AM - 10:30 AMLearning Objectives:Describe the pathophysiological roles of protease activated receptors as critical regulators of the microenvironment after traumatic spinal cord injury.

Participants:

1Yoon H, 2Radulovic M, 3Scarisbrick I1Department of Physical Medicine and Rehabilitation, Mayo Clinic , Rochester , Minnesota, USA; 2Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic , Rochester , Minnesota, USA; 3Rehabilitation Medicine Research Center, Department of Physiology and Biomedical Engineering, Neurobiology of Disease Program, Mayo Clinic , Rochester , Minnesota, USAHyesook Yoon, PhDDepartment of Physical Medicine and Rehabilitation, Mayo Clinic Bio:Hyesook Yoon, PhD, is a Research Scientist in the Departments of Physical Medicine and Rehabilitation, an Assistant Professor in the Departments of Physiology, College of Medicine in Mayo Clinic, Rochester Minnesota, USA. After earning her Bachelor’s and Master degrees in Chemistry and Biochemistry with a focused on enzyme kinetics, Hyesook received his PhD degree (2008) in the field o Biochemistry from Florida State University, Tallahassee, Florida. After completing her first Postdoctoral research fellowship at Mount Sinai Hospital, Toronto, CA, she joined Mayo Clinic. She published 18 manuscripts, 12 as first author, which reflects extremely well on her capacity of scientific research success. Hyesook has also received several awards including a Career Development Award from Center for Multiple Sclerosis and Demyelinating Disease, the most outstanding platform presentation award, Young Scientist Travel Award and Young Investigator Award. She has provided outstanding contributions in the area of biochemical mechanisms of traumatic injury of spinal cord. Importantly, she discovered that the kallikreins operate in the activation cascades with the classic thrombolytic and fibrinolytic coagulation enzyme, including thrombin and plasmin, thereby uncovering important links between these enzymatic families and novel mechanism of physiological action.Education:Kyung Hee University (Kyunggi-do, South Korea), BS 1995-1999 Chemistry Hanyang University (Seoul, South Korea), MS 1999-2001 Biochemistry Florida State University (Tallahassee, FL), PhD 2003-2008 Biochemistry Mount Sinai Hospital (Toronto, Canada), Postdoctoral Fellow 2008-2009 Pathology Florida State University (Tallahassee, FL), Postdoctoral Fellow 2009-2010 Biomedical Sciences Mayo Clinic (Rochester, MN), Research Associate 2010-2014 Physical Medicine and RehabilitationThis author has no relevant disclosures.Maja Radulovic, PhDMayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic This author has no relevant disclosures.Isobel Scarisbrick, PhDRehabilitation Medicine Research Center, Department of Physiology and Biomedical Engineering, Neurobiology of Disease Program, Mayo Clinic This author has no relevant disclosures.

95Modulation of Trunk Stimulation to Improve Efficiency of Manual Wheelchair PropulsionThursday, May 03, 2018 09:30 AM - 10:30 AM

Learning Objectives:To understand how modulation of trunk stimulation can improve the efficiency of manual wheelchair propulsion.

Participants:1Bailey S, 1Foglyano K, 1Lombardo L, 2Triolo R1Louis Stokes Cleveland Va Medical Center , Cleveland , , USA; 2Case Western Reserve University/Cleveland Va Medical Center , Cleveland , OH, USAStephanie Bailey, BSLouis Stokes Cleveland Va Medical Center This author has no relevant disclosures.Kevin Foglyano, BSLouis Stokes Cleveland Va Medical Center This author has no relevant disclosures.Lisa Lombardo, MSPTLouis Stokes Cleveland Va Medical Center This author has no relevant disclosures.Ronald Triolo, Ph.D.Case Western Reserve University/Cleveland Va Medical Center Bio:Ronald Triolo received a BS in Electrical Engineering from Villanova University, Villanova PA in 1980, and MS degrees in both Biomedical and Electrical Engineering from Drexel University in Philadelphia PA in 1982 and 1984, respectively, followed in 1986 by a doctorate in Biomedical Engineering for the design and clinical testing of an actively powered myoelectrically controlled above-knee prosthesis for trans-femoral amputees. Dr. Triolo was Director of Research at the Philadelphia Shriners Hospital from 1986 through 1994 where he investigated neuroprosthetic and neurotherapeutic uses of neural stimulation for children with spinal cord injury or cerebral palsy. He is currently a tenured Professor of Biomedical Engineering at Case Western Reserve University and a Senior Career Scientist with the Rehabilitation Research & Development Service of the US Department of Veterans Affairs. Dr. Triolo is the Executive Director of the Center for Advanced Platform Technology of the Department of Veterans Affairs where he oversees the design, prototyping and production of novel medical devices and neural interfaces for the rehabilitation of individuals with paralysis, sensorimotor impairments or limb loss. He also directs the Motion Study Laboratory at the Louis Stokes Cleveland Veterans Affairs Medical Center where he pursues original research in the development and clinical application of peripheral nerve approaches for neuroprosthetic, neurotherapeutic and restorative technologies, limb prosthetics/orthotics, and dynamic exoskeletal systems along with the quantitative assessment of their outcomes. Dr. Triolo has authored over 130 peer-reviewed journal articles, 250 conference abstracts, 13 book chapters and 6 patents. He currently leads independently funded research programs sponsored by the NIH, VA, DoD, DARPA and the Craig H. Nielsen Foundation to restore or enhance the upright and seated mobility, posture and balance in individuals with neuro-musculo-skeletal disorders such as stroke, multiple sclerosis and spinal cord injury, and to restore natural sensation to lower limb amputees.

Education:Villanova University, Villanova PA BS 1980 Electrical Engineering Drexel University, Philadelphia PA MS 1982 Biomedical Engineering Drexel University, Philadelphia PA MS 1984 Electrical Engineering Drexel University, Philadelphia PA Ph.D. 1986 Biomedical Engineering This author has no relevant disclosures.

96Leveraging information from many to better serve the individual: A healthcare tool for personalized prioritization of Clinical Practice Guidelines in pressure injury management.Thursday, May 03, 2018 09:30 AM - 10:30 AMLearning Objectives:Describe current strengths and challenges with applying Clinical Practice Guidelines for pressure injury prevention.

Participants:1Bogie K, 2Henzel K, 3Zhang G, 3Roggenkamp S, 4Sun J, 4Bloostein A, 2Seton J, 2Richmond M, 2Washington M, 2McDaniel J, 2Graebert J, 2Lemmer D, 2Schwartz K1Case Western Reserve University/Louis Stokes Cleveland Va Medical Center , Cleveland , OH, USA; 2Louis Stokes Cleveland Va Medical Center , Cleveland , OH, USA; 3University of Kentucky , Nashville , TN, USA; 4Case Western Reserve University , Cleveland , OH, USAKath Bogie, D.PhilCase Western Reserve University/Louis Stokes Cleveland Va Medical Center Bio:Dr. Kath Bogie is a biomedical engineer who pursues translational research focused on improving patient-centered wound management. Dr. Bogie trained in England at the University of Manchester Institute of Science and Technology followed by a D.Phil in Biomedical Engineering from the University of Oxford. She is currently an Associate Professor in the Dept of Orthopaedics at Case Western Reserve University. At the Cleveland Dept of Veterans Affairs Medical Center Dr. Bogie is a Senior Research Scientist and Director of Health Maintenance and Monitoring within the Advanced Platform Technology Center. Current interdisciplinary translational research include determination of personalized pressure injury risk based on identification of novel biomarkers, using bioinformatics to enable the development of a personalized healthcare tool for pressure injury prevention planning and development of a smart electroceutical bandage to deliver effective wound therapy outside traditional clinical settings.Education:University of Manchester Institute of Science and Technology, Manchester, UK B.Sc.(Hons.) 06/1984 Metals and Materials Technology

University of Oxford, Oxford, UK D.Phil. 08/1998 Biomedical Engineering This author has the following disclosures:

Research Support

Kristi Henzel, MD, PhDLouis Stokes Cleveland Va Medical Center This author has no relevant disclosures.GQ Zhang, PhDUniversity of Kentucky This author has the following disclosures:

Research SupportSteve Roggenkamp, University of Kentucky This author has the following disclosures:

Research SupportJiayang Sun, PhDCase Western Reserve University This author has the following disclosures:

Research SupportArielle Bloostein, Case Western Reserve University This author has the following disclosures:

Research SupportJacinta Seton, Louis Stokes Cleveland Va Medical Center This author has the following disclosures:

Research SupportMaryAnn Richmond, MD, DVMLouis Stokes Cleveland Va Medical Center This author has no relevant disclosures.Monique Washington, Louis Stokes Cleveland Va Medical Center This author has no relevant disclosures.John McDaniel, PhDLouis Stokes Cleveland Va Medical Center This author has the following disclosures:

Research SupportJennifer Graebert, Louis Stokes Cleveland Va Medical Center This author has the following disclosures:

Research SupportDavid Lemmer, Louis Stokes Cleveland Va Medical Center This author has the following disclosures:

Research Support

Katie Schwartz, Louis Stokes Cleveland Va Medical Center This author has the following disclosures:

Research Support

97Effect of Interface Peak Pressures following the 4th Spine Board ModificationThursday, May 03, 2018 09:30 AM - 10:30 AMLearning Objectives:To assess the peak interface pressures on the head, scapulothoracic (ST), sacroiliac (SI), and heel regions on a standard spine board (SSB) and a fourth pressure reducing modification of a proof of concept spine board (P-4) during spinal immobilization.

Participants:1Robles G, 2Roach M, 1Nemunaitis G1Metrohealth Rehabilitation Institute of Ohio/Case Western Reserve University , Cleveland , Ohio, United states; 2Metrohealth System/Case Western Reserve University , Cleveland , Ohio, United statesGeorge Robles, MDMetrohealth Rehabilitation Institute of Ohio/Case Western Reserve University Bio:George A Robles, MD, is a post graduate 4th year resident in Physical Medicine and Rehabilitation at the MetroHealth Rehabilitation Institute of Ohio/Case Western Reserve University residency training program. After receiving his Bachelor of Arts degree in Environmental science and a Bachelor of Science in BioResource science from the University of California at Berkeley, he became a staff research associate within the Department of Laboratory Medicine at the University of California in San Francisco. While there he worked on projects working towards elucidating the basic structure and potential inhibition targets for the HIV integrase enzyme. He went on to pursue a career in healthcare and in 2001 received his medical degree from the Royal College of Surgeons in Ireland before completing an internship and basic specialist training in general internal medicine from James Connolly Memorial Hospital in Dublin. He completed a one year rotation as a Medical Registrar at the National Rehabilitation Hospital-Ireland in 2006 before becoming Medical Officer in the Department of Geriatrics at Our Lady’s Hospice and Care Services serving as staff physician for long term, palliative, and short-stay physical rehabilitation patients. In 2014 he started US residency training in Physical Medicine and Rehabilitation and is due to graduate in June 2018. Education:University of California (Berkeley, CA), BS 1988-1993 BioResource Science. University of California (Berkeley, CA), BA 1988-1993 Environmental Science. Royal College of Surgeons (Dublin, Ireland), MD 1996-2001 Medicine James Connolly Memorial Hospital (Dublin, Ireland), 6/2002 Internship - combined IM/Surgery.

James Connolly Memorial Hospital (Dublin, Ireland), 6/2004 Basic Specialist Training - Internal Medicine

MetroHealth/Case Western Reserve University (Cleveland, OH) 2014-present, Categorical Residency in PM&RThis author has no relevant disclosures.Mary Joan Roach, PhDMetrohealth System/Case Western Reserve University Bio:N/AEducation:N/AThis author has no relevant disclosures.Gregory Nemunaitis, MDMetrohealth Rehabilitation Institute of Ohio/Case Western Reserve University Bio:N/AEducation:N/AThis author has no relevant disclosures.

98Racial/Ethnic Differences in Obesity in Individuals with Spinal Cord Injury: The Impact of Disadvantaged Neighborhood Thursday, May 03, 2018 09:30 AM - 10:30 AMLearning Objectives:discuss the role of neighborhood in the relationship between race and obesity in people with spinal cord injury.

Participants:1Wen H, 1Chen Y, 2Botticello A, 1Bae S1University of Alabama at Birmingham , Birmingham , Alabama, United states; 2 Kessler Foundation , West Orange , new jerse, USHUACONG Wen, MSUniversity of Alabama at Birmingham Bio:Wen, Huacong, MS, is a third year PhD student in the Program of Rehabilitation Science at the University of Alabama (UAB) in Birmingham, Alabama. Ms. Wen finished her medical training in China, and started to pursue research related to health of people with spinal cord injury (SCI) since Master program. After joining the Rehabilitation Science program at UAB, Ms. Wen has been working as a research assistant at the National Spinal Cord Injury Database (NSCID) for a year and participated as a co-principal investigator in a secondary data analysis of NSCID linked with US census data that was funded by UAB Mid-South Transdisciplinary Collaborative Center. In her short academic career she has already published one first-authored article, presented study findings at local and national professional conferences, and won an early career

poster award at the national professional conference. She studies health in people with SCI, with an interest in investigating risk and protective factors of obesity and mortality. Education:Chengdu University of Traditional Chinese Medicine (Chengdu, China), BS 2006-2011 Rehabilitation Medicine; Nanjing Medical University (Nanjing, China), MS 2011-2014, Rehabilitation Medicine & Physical Therapy; University of Alabama at Birmingham (Birmingham, AL, USA), PhD 2015-present Rehabilitation Science

This author has no relevant disclosures.Yuying Chen, MD, PhDUniversity of Alabama at Birmingham This author has no relevant disclosures.Amanda Botticello, PhD, MPHKessler Foundation This author has no relevant disclosures.Sejong Bae, PhDUniversity of Alabama at Birmingham This author has no relevant disclosures.

99Vasomotor and Sudomotor Activity during Heat Stress in Persons with Spinal Cord InjuryThursday, May 03, 2018 09:30 AM - 10:30 AMLearning Objectives:1. Appreciate that vasomotor and sudomotor activity is discordant in persons with SCI.

Participants:Trbovich M, Kellogg DUt Health Science Center at San Antonio , San Antonio , Texas, USAMichelle Trbovich, MDUt Health Science Center at San Antonio Bio:Dr. Trbovich is a Spinal Cord Injury physician working as a staff physician at the South Texas Veteran’s Health Care Center in San Antonio and an Assistant Professor in the Department of Rehabilitation Medicine at the University of TX Health Science Center at San Antonio. She completed her medical degree and PM&R residency at the University of Texas Health Science Center at San Antonio. Following residency, she completed a Spinal Cord Injury Fellowship at Stanford University and an Advanced SCI Research Fellowship at the Palo Alto VA Health Care System. She is board certified in both Physical Medicine and Rehabilitation and Spinal Cord Injury and remain an active member of national SCI organizations. She currently serves on the International Autonomic Standards Committee within ASIA. In 2016, she received a Career Development Award from the Rehabilitation and Research Development department of the VA under which she is currently studying the neurovascular controls of thermoregulation after spinal

cord injury. In addition to her research in the area of thermoregulation after SCI, she is interested in neuropathic pain after SCI and has a grant funding a clinical trial testing the efficacy of the capsaicin 8% patch in persons with SCI. Education:Rice University (Houston, TX), BA 1997-2001 Kinesiology

UT Health Science Center at San Antonio (San Antonio, TX), MD 2001-2005 Medicine

UT Health Science Center at San Antonio (San Antonio, TX), 2005-2009 , PM&R

Stanford University (Stanford, CA), 2009-2010, Spinal Cord Injury Fellowship

VA Palo Alto Health Care System (Palo Alto, CA) 2010-2011. Spinal Cord Injury Advanced Research Fellowship. This author has no relevant disclosures.Dean Kellogg, MD, PhDUt Health Science Center at San Antonio This author has the following disclosures:

100The use of machine learning algorithms for predicting the functional recovery following traumatic spinal cord injuryThursday, May 03, 2018 09:30 AM - 10:30 AMLearning Objectives:Study the potential of machine learning algorithms to predict the long term functional recovery following traumatic spinal cord injury and assess the effect of reducing the number of predictors on the performances of the model.

Participants:1Facchinello Y, 2Beauséjour M, 1Richard-Denis A, 1Thompson C, 1Mac-Thiong J1Research Center, Hôpital Du Sacré-Coeur De Montréal , Montréal , QC, Canada; 2Department of Surgery, Faculty of Medicine, University of Montreal , Montreal , QC, CanadaYann Facchinello, PhDResearch Center, Hôpital Du Sacré-Coeur De Montréal This author has no relevant disclosures.Marie Beauséjour, PhDDepartment of Surgery, Faculty of Medicine, University of Montreal This author has no relevant disclosures.Andréane Richard-Denis, MDResearch Center, Hôpital Du Sacré-Coeur De Montréal This author has no relevant disclosures.Cynthia Thompson, PhDResearch Center, Hôpital Du Sacré-Coeur De Montréal

This author has no relevant disclosures.Jean-Marc Mac-Thiong, Research Center, Hôpital Du Sacré-Coeur De Montréal Bio:Jean-Marc Mac-Thiong, MD, PhD, is a clinician-scientist practicing as an orthopedic spine surgeon at the Hopital du Sacre-Coeur de Montreal, with a multidisciplinary background in spine surgery (MD, fellowship), biomedical sciences (MSc, PhD), and engineering (BEng). He is an associate professor of surgery and research director of the Orthopedics Division at Université de Montréal. He is Chairman of the Medtronic Research Chair in spinal trauma at Université de Montréal and in charge of the Rick Hansen Spinal Cord Injury Registry at Hopital du Sacre-Coeur de Montreal. He is Chair of the Spine/Acute care Committee at the American Spinal Injury Association. His research has been supported by the Canadian Funds for Innovation, Natural Sciences and Engineering Research Council of Canada, Department of the US Army, Fonds de recherche du Québec – Santé, Fonds de recherche du Québec – Nature et technologies, and Scoliosis Research Society. He has focused his research on acute predictors of the outcome after a traumatic spinal cord injury, and on the biomechanical and experimental characterization of traumatic spinal cord injury.Education:École Polytechnique de Montréal, Canada, B.Eng. 1997, Mechanical engineering Université de Montréal, Canada, M.S., 2001, Biomedical Sciences Université de Montréal, Canada, M.D., 2002, Medicine Université de Montréal, Canada, Residency, 2007, Orthopedic surgery Université de Montréal, Canada, Ph.D., 2008, Biomedical Sciences Twin Cities Spine Center, Minneapolis, USA, Fellowship, 2008, Spine surgery

This author has the following disclosures: Research Support Shareholder

Co-founder and shareholder (30%) of Spinologics Inc. Head of Medtronic Research Chair in spinal trauma at University of Montreal Financial support from Medtronic of Canada for 1 fellow per year in spinal surgery at Hopital du Sacre-Coeur de Montreal

101Barriers to employment among those with spinal cord dysfunction: A comparison of participants with SCI and MSThursday, May 03, 2018 09:30 AM - 10:30 AMLearning Objectives:To identify employment rates, barriers, and facilitators to employment among those with SCI and to compare them with those with MS.

Participants:Krause J, Cao Y, Jarnecke MMedical University of South Carolina , Charleston , SC, United states

James Krause, PhDMedical University of South Carolina Bio:James S. Krause, PhD holds the rank of Professor and serves as the Associate Dean for Research in the College of Health Professions at the Medical University of South Carolina (MUSC). He is the Director of the Center for Rehabilitation Research in Neurologic Conditions and Scientific Director of the South Carolina Spinal Cord Injury Research Fund which provides funding for basic, applied, and interdisciplinary studies of spinal cord injury (SCI). After receiving his Bachelor’s degree from the University of Minnesota in 1980, he continued at the University of Minnesota and obtained his PhD in Psychology in 1990. Dr. Krause has served as first author on over 115 articles in peer-reviewed journals and has made over 265 presentations at national and international professional conferences. He has published extensively on SCI including the areas of employment, vocational interests, quality of life, health and secondary conditions, and risk for early mortality. Education:University of Minnesota, Minneapolis, MN BA 1980 Psychology

University of Minnesota, Minneapolis, MN PhD 1990 Psychology This author has the following disclosures:

Research SupportUS Department of Health and Human Services Administration for Community Living, NIDILRR grant numbers 90DP0050 and 90RT5035. Yue Cao, PhDMedical University of South Carolina This author has the following disclosures:

Research SupportUS Department of Health and Human Services Administration for Community Living, NIDILRR grant numbers 90DP0050 and 90RT5035. Melinda Jarnecke, Medical University of South Carolina This author has the following disclosures:

Research SupportUS Department of Health and Human Services Administration for Community Living, NIDILRR grant numbers 90DP0050 and 90RT5035.

102Comparison of abdominal compression devices in persons with abdominal paralysis due to spinal cord injury.

Thursday, May 03, 2018 09:30 AM - 10:30 AMLearning Objectives:Discuss the impact of abdominal compression on improving physiological outcomes in persons with abdominal paralysis due to SCI.

Participants:Hastings J, De Groot M, Swartz JUniversity of Puget Sound , Tacoma , WA, USAJennifer Hastings, PT, PhD, NCSUniversity of Puget Sound Bio:Jennifer Hastings is a professor of Physical Therapy at the University of Puget Sound. Dr. Hastings began teaching in 1995 and has maintained clinical practice since earning her PT license working throughout the spectrum of neurologic care (ICU through outpatient and home health). Dr. Hastings shares responsibility for instruction in adult neurologic rehabilitation and also teaches professional issues and adult systemic pathology courses. She is expert in spinal cord injury management, seating and wheelchair prescription, and orthopedic complications of neurologic disease. Dr. Hastings practiced twenty years in inpatient SCI rehabilitation within the VA healthcare system.Currently, she has a small private practice for wheelchair seating and prescription and functional training for SCI. Dr. Hastings actively researches physical therapy interventions for neurologic clients and has published in Archives of Physical Medicine and Rehabilitation, Physical Therapy, and The American Journal of Physical Medicine and Rehabilitation.Education:Education:

Doctor of Philosophy University of Washington, School of Nursing Seattle, WA Nursing Science June 2006 Dissertation: Effectiveness of Postural Intervention via Manual Wheelchair Change; Feasibility of Teleconsultation Delivery

Master of Science Boston University, Sargent College Boston, MA Physical Therapy May 1985 Thesis: The long term use of lower extremity bracing following spinal cord injury rehabilitation

Bachelor of Arts University of California Berkeley, CA

Physiology August 1981

This author has no relevant disclosures.Michaela De Groot, SPTUniversity of Puget Sound Bio:not required this is not a courseEducation:not required this is not a courseThis author has no relevant disclosures.Jennifer Swartz, SPTUniversity of Puget Sound Bio:not required this is not a courseEducation:not required this is not a courseThis author has no relevant disclosures.

103Changes in spinal cord mitochondria with high fat diet consumption: Implications for the trajectory of recovery after spinal cord injuryThursday, May 03, 2018 09:30 AM - 10:30 AMLearning Objectives:Obesity and metabolic syndrome cause detrimental effects on mitochondria in various tissues including liver and muscle, but the specific effects on the intact spinal cord or in the context of injury is largely unexplored. Importantly, it was recently shown that changes in mitochondrial morphology and function occur following acute spinal cord injury (SCI) (Jia et al, 2016). Here, we seek to illuminate metabolic and mitochondrial changes occurring in the spinal cord of adult mice with diet induced obesity and signs of metabolic syndrome.

Participants:Langley M, Yoon H, Kim H, Lanza I, Matveyenko A, LeBrasseur N, Scarisbrick IMayo Clinic , Rochester , MN, United statesMonica Langley, PhDMayo Clinic Bio:Monica Langley, PhD, is a Research fellow in the neural repair laboratory of Dr. Isobel Scarisbrick at the Mayo Clinic in Rochester, MN. Following completion of her Bachelor’s degree in Biology at the University of Wisconsin- Parkside in 2009, she recently earned her Doctoral degree in Toxicology from Iowa State University in 2017. Through Iowa State and the Society of Toxicology, Dr. Langley was heavily involved in organizing local and regional conferences, workshops, and symposia. She has published manuscripts in high impact journals,

presented at regional and national meetings, and received a number of prestigious awards recognizing her work in neurotoxicology, drug discovery, stem cells, and pathology. She is currently funded in part by a fellowship from the Mayo Clinic Center for Multiple Sclerosis and Autoimmune Neurology. Currently, her work focuses on the effects of high fat diet on mitochondria function in the brain and spinal cord in models of Multiple Sclerosis and spinal cord injury.Education:University of Wisconsin- Parkside (Kenosha, WI), BS 2005-2009 Biology Iowa State University (Ames, IA), PhD 2011-2017, Toxicology Mayo Clinic (Rochester, MN), Research fellowship, 2017- , Physical Medicine and Rehabilitation This author has no relevant disclosures.Hyesook Yoon, PhDMayo Clinic This author has no relevant disclosures.Haneui Kim, PhDMayo Clinic This author has no relevant disclosures.Ian Lanza, PhDMayo Clinic This author has no relevant disclosures.Aleksey Matveyenko, PhDMayo Clinic This author has no relevant disclosures.Nathan LeBrasseur, PhDMayo Clinic This author has no relevant disclosures.Isobel Scarisbrick, PhDMayo Clinic This author has no relevant disclosures.

104Managing and experiencing severe neuropathic pain after SCI: a qualitative studyThursday, May 03, 2018 09:30 AM - 10:30 AMLearning Objectives:To increase the participants’ understanding of the perceived barriers and facilitators to optimal control of severe neuropathic pain after SCI, i.e., the perspectives of the person with SCI and severe neuropathic pain, their significant others, and healthcare providers.

Participants:1Widerstrom-Noga E, 1Anderson K, 1Cambridge J, 2Perez S, 2Martinez-Arizala A1The Miami Project to Cure Paralysis, University of Miami, Miller School of Medicine , Miami , Florida, USA; 2Miami Veterans Administration Health Care System , Miami , Florida, USA

Eva Widerstrom-Noga, DDS, PhDThe Miami Project to Cure Paralysis, University of Miami, Miller School of Medicine Bio:Dr. Eva Widerstrӧm-Noga is a Professor of Neurological Surgery and Rehabilitation Medicine and the Principal Investigator of the Clinical Pain Research Laboratory of The Miami Project to Cure Paralysis. Her expertise is in cross-disciplinary pain research (pain physiology and pain psychology) in neurotrauma populations (spinal cord injury and traumatic brain injuries). She has performed human pain research for more than 24 years and in the field of SCI for over 20 years. Dr. Widerstrӧm-Noga has adapted outcome measures used to classify and assess pain in other chronic pain populations to people with SCI. She has published over 60 peer reviewed journal articles and written eight book chapters on pain and pain assessment. Her present research program is interdisciplinary and involves both qualitative and quantitative pain methodologies including quantitative sensory testing and MR spectroscopic brain imaging. Education:University of Gothenburg, Gothenburg, Sweden D.D.S. 1986 Dental Surgery

University of Gothenburg, Gothenburg, Sweden Ph.D. 1993 Pain Physiology This author has no relevant disclosures.Kimberly Anderson, PhDThe Miami Project to Cure Paralysis, University of Miami, Miller School of Medicine This author has no relevant disclosures.Jessica Cambridge, MPHThe Miami Project to Cure Paralysis, University of Miami, Miller School of Medicine This author has no relevant disclosures.Salome Perez, PhDMiami Veterans Administration Health Care System This author has no relevant disclosures.Alberto Martinez-Arizala, MDMiami Veterans Administration Health Care System This author has no relevant disclosures.

105Six Months of Intensive Lifestyle Intervention Lessens Cardiometabolic Component Risks in Persons with SCI and their Caregivers: A Two Dyad Case Study Thursday, May 03, 2018 09:30 AM - 10:30 AMLearning Objectives:Attendees will: Understand the role of lifestyle intervention on lessening cardiometabolic component risks in persons with SCI.

Participants:Nash M, Betancourt L, Bigford G, Maher J, Anthony M, Mendez AUniversity of Miami Miller School of Medicine , Miami , Florida, USA

Mark Nash, PhDUniversity of Miami Miller School of Medicine Bio:Mark S. Nash, Ph.D., FACSM is a tenured Professor of Neurological Surgery and Physical Medicine & Rehabilitation at the University of Miami School of Medicine, Principal Investigator of the Applied Physiology Research Laboratory for the Miami Project to Cure Paralysis, and Director of Research in Physical Medicine & Rehabilitation. He is a Fellow of the American College of Sports Medicine. Dr. Nash has primary interests in assessment/treatment of cardiometabolic disease risks after SCI. He has published more than 120 peer-review articles, scholarly monographs, and book chapters on these themes and related topics within rehabilitation physiology. He is currently an Editorial Board Member for Topics in SCI Rehabilitation, Chair of the ASIA Research & Awards Committee, and Chair of the PVA Consortium for Spinal Cord Medicine Guideline Panel on Cardiometabolic Disorders. He is Co-Director of the NIDILRR South Florida SCI Model System, and PI for a recently awarded multi-center NIDILRR Disability Rehabilitation Research Project examining lifestyle intervention on cardiometabolic risks in stakeholders with SCI and their caregivers. Education:

University of Toledo B.S., 1976 Biology

University of Toledo M.S., 1980 Human Physiology

University of Toledo and Medical College of Ohio at Toledo Ph.D., 1984 Applied Physiology and Clinical Anatomy This author has no relevant disclosures.Luisa Betancourt, MD, MSUniversity of Miami Miller School of Medicine This author has no relevant disclosures.Gregory Bigford, Ph.D.University of Miami Miller School of Medicine This author has no relevant disclosures.Jennifer Maher, Ph.D.University of Miami Miller School of Medicine This author has no relevant disclosures.Musto Anthony, Ph.D.University of Miami Miller School of Medicine This author has no relevant disclosures.Armando Mendez, Ph.D.University of Miami Miller School of Medicine

This author has no relevant disclosures.

106Comparison of shoulder joint motion and kinetics during fast and inclined reverse and conventional manual wheelchair propulsion in persons with paraplegiaThursday, May 03, 2018 09:30 AM - 10:30 AMLearning Objectives:Attendees will be able to describe how reverse propulsion (RW, rSW) alters shoulder motion and shoulder forces compared to traditional forward manual WC propulsion (fSW) and how this alternative rear wheel could protect the shoulders and preserve mobility and independence for manual WC users.

Participants:1Lighthall Haubert L, 1Requejo P, 1Mulroy S, 1Maneekobkunwong S, 1Rodriguez D, 2Gronely J1Rancho Los Amigos National Rehabilitation Center, Pathokinesiology Laboratory , Downey , California, United states; 2Rancho Los Amigos National Rehabilitation Center , Downey , California, United statesLisa Lighthall Haubert, MPT, KEMGRancho Los Amigos National Rehabilitation Center, Pathokinesiology Laboratory Bio:Lisa Lighthall Haubert earned her Master of Physical Therapy degree from the University of Southern California in 1996. She practiced in outpatient orthopedic physical therapy, with an emphasis in pre- and post-surgical shoulder rehabilitation, until 1999, when she came to Rancho Los Amigos National Rehabilitation Center (RLANRC). She worked in the outpatient physical therapy department and the joint replacement service for two years, at which time she was also an intervention physical therapist for two research studies with the University of Southern California looking at the effectiveness of upper extremity therapy interventions post-stroke, including the EXCITE national clinical trial. She has been a research physical therapist and kinesiologic electromyographer in the Pathokinesiology Service at RLANRC since 2001. She received her certification in kinesiologic electromyography in 2005. She has contributed to many grants including data collection and analysis, publication of results in abstracts and manuscripts, and podium and poster presentations at scientific meetings. These grants have focused on the prevention of shoulder pain and preservation of mobility and participation as well increasing physical activity and reducing pain for individuals with spinal cord injury. Lisa has also been adjunct clinical faculty at the University of Southern California in the Biokinesiology and Physical Therapy Department. Education:University of California at Santa Barbara (Santa Barbara, CA), BS 1989 -1993 Biopsychology

University of Southern California (Los Angeles, CA), Master of Physical Therapy 1994-996

Pathokinesiology Laboratory at Rancho Los Amigos National Rehabilitation Center, Kinesiologic Electromyography Training 2002-2004

This author has the following disclosures: Research Support

RoWheels/Grant FundingPhilip Requejo, PhDRancho Los Amigos National Rehabilitation Center, Pathokinesiology Laboratory This author has the following disclosures:

Research SupportRoWheels/Grant FundingSara Mulroy, Rancho Los Amigos National Rehabilitation Center, Pathokinesiology Laboratory This author has the following disclosures:

Research SupportRoWheels/Grant FundingSomboon Maneekobkunwong, MSMERancho Los Amigos National Rehabilitation Center, Pathokinesiology Laboratory This author has the following disclosures:

Research SupportRoWheels/Grant FundingDiego Rodriguez, BSRancho Los Amigos National Rehabilitation Center, Pathokinesiology Laboratory This author has the following disclosures:

Research SupportRoWheels/Grant FundingJoAnne Gronely, DPTRancho Los Amigos National Rehabilitation Center This author has the following disclosures:

Research SupportRoWheels/Grant Funding

107Early opportunities to improve chronic functional outcome following traumatic spinal cord injuryThursday, May 03, 2018 09:30 AM - 10:30 AMLearning Objectives:Main objective: To identify factors that are consistently and independently associated with global functional outcome in individuals with traumatic spinal cord injury, through their level of importance and through the proposition of a new conceptual framework.

Objectif 2: Identify factors that are modifiable in the early process following traumatic spinal cord injury.

Participants:Richard-Denis AHôpital Du Sacré-Coeur De Montréal , Montreal , Quebec, CanadaAndréane Richard-Denis, MD, MScHôpital Du Sacré-Coeur De Montréal Bio:Dr. Richard-Denis is an emergent clinician-researcher and assistant professor in the department of specialized medicine at University of Montreal. She is a regular researcher at the Sacre-Cœur Hospital Research Center. After completing her residency in physical medicine and rehabilitation and completed a Master's degree in biomedical sciences both at University of Montreal in 2016. She is also chief of the service of physical medicine and rehabilitation of the Sacre-Coeur Hospital. She specializes in rehabilitation following a spinal cord injury with a special interest in the acute care management. Dr. Richard-Denis is also an emergent clinician-researcher in provincial reasearch society (REPAR) and Member of the American Spinal Injury since 2015. She has presented her work in previous national and international conferences notably on the influence of the acute care on the chronic functional outcome following traumatic spinal cord injury.Education:University of Sherbrooke (Quebec, Canada), Medicinae doctor (M.D.) 2004-2008

University of Montreal (Quebec, Canada), Physical Medicine and Rehabilitation residency 2008-2013

University of Montreal (Quebec, Canada) Master in biomedical Sciences (MSc) 2013-2016.This author has the following disclosures:

Research SupportMENTOR program of the Canadian Institute of Health Research (CIHR).

108A Case Report on an Adolescent with Transverse Myelitis and Suspected Conversion DisorderThursday, May 03, 2018 09:30 AM - 10:30 AMLearning Objectives:1. The learner will be able to describe the negative impact of a suspected psychological process on the functional mobility of an adolescent with transverse myelitis.

Participants:Scharff K, Lipa B, Russell HShriners Hospitals for Children - Philadelphia , Philadelphia , PA, 19140Kimberly Scharff, PT, DPT, PCSShriners Hospitals for Children - Philadelphia Bio:Kimberly A. Scharff, PT, DPT, PCS is a physical therapist at Shriners Hospitals for Children –

Philadelphia. She received a Bachelor of Science degree in Biology from Villanova University, a Master of Education degree from Cabrini College, and a Doctorate of Physical Therapy degree from Drexel University in 2006. She is a Pediatric Clinical Specialist as designated by the American Physical Therapy Association. She has ten years of experience evaluating and treating children and youth with spinal cord injuries. She is the current co-chair of the ASIA Pediatrics Committee. Education:Drexel University, Philadelphia, PA Doctorate of Physical Therapy, May 2006

Cabrini College, Radnor, PA Master of Education, August 2000

Villanova University, Villanova, PA Bachelor of Science in Biology, May 1996 This author has no relevant disclosures.Bethany Lipa, MDShriners Hospitals for Children - Philadelphia This author has no relevant disclosures.Heather Russell, Ph.D.Shriners Hospitals for Children - Philadelphia This author has no relevant disclosures.

109The impact of metabolic risk factors on FIM efficiency during acute rehabilitation: a retrospective study of traumatic spinal cord injuryThursday, May 03, 2018 09:30 AM - 10:30 AMLearning Objectives:To describe the impact of metabolic dysfunction on FIM efficiency in the acute stage of rehabilitation following traumatic thoracic SCI.

Participants:Kleven A, Hoppe K, Reeves R, Hollman J, Scarisbrick IMayo Clinic Department of Physical Medicine and Rehabilitation , Rochester, Mn , MN, USAAndrew Kleven, DPTMayo Clinic Department of Physical Medicine and Rehabilitation Bio:Andrew D. Kleven, DPT is a recent graduate of the Mayo Clinic Program in physical therapy. He has worked closely with Dr. Isobel Scarisbrick, PhD in the Rehabilitation Medicine Research Center at the Mayo Clinic to identify the impact of Metabolic Syndrome on spinal cord injury at the cellular and functional outcomes level. He is currently attending the Medical College of Wisconsin medical school.

Education:Saint Olaf College (Northfield, MN), BA 2010-2014 Exercise Science

Mayo Clinic Program in Physical Therapy, DPT 2014-2017

Medical College of Wisconsin, MD candidate 2017 to presentThis author has no relevant disclosures.Kurt Hoppe, MDMayo Clinic Department of Physical Medicine and Rehabilitation This author has no relevant disclosures.Ronald Reeves, MDMayo Clinic Department of Physical Medicine and Rehabilitation This author has no relevant disclosures.John Hollman, PhDMayo Clinic Department of Physical Medicine and Rehabilitation This author has no relevant disclosures.Isobel Scarisbrick, PhDMayo Clinic Department of Physical Medicine and Rehabilitation This author has no relevant disclosures.

110A 3-Phase Interdisciplinary Quality Improvement Project Optimizing Neurogenic Bladder Care Documentation in an SCI Unit at a Veterans Administration Medical CenterThursday, May 03, 2018 09:30 AM - 10:30 AMLearning Objectives:Objective: To improve intermittent catheter paper documentation in the SCI Unit of the Louis Stokes Veterans Administration Medical Center.

Participants:1Tamayo N, 2Kiefer P, 2Willoughby G, 2Henzel M1Case Western University Metrohealth Hospital , Cleveland , OH, USA; 2Louis Stokes Veterans Administration Medical Center , Cleveland , OH, USANina Carmela Tamayo, MS, MPH, DOCase Western University Metrohealth Hospital Bio:Niña Carmela R. Tamayo, MS MPH DO is a current Spinal Cord Injury Fellow at Case Western University MetroHealth Hospital. Dr. Tamayo graduated from the University of Chicago with a Bachelor of Arts in Biology with a specialization in Endocrinology in 2006, and also earned two Master’s degrees from Columbia University in Nutrition and Health Policy and Administration from 2007-2009. She then went on to earn her Doctor of Osteopathy from the University of Medicine and Dentistry of New Jersey School of Osteopathic Medicine (now Rowan University SOM) in 2013. She completed her residency in Physical Medicine and Rehabilitation at Mercy Medical Center in Long Island, New York, where she served on the Graduate Medical Education

Committee as the resident liaison, and as the Chief Resident for two years. Dr. Tamayo has served in other leadership roles including the ASIA Standards Committee and the Resident Physician Council of the American Osteopathic College of Physical Medicine and Rehabilitation. Dr. Tamayo has participated in a variety of research from basic science to clinical research. Her research interests lies in the intersection of rehabilitation medicine, nutrition, public health, and health policy. Education:July 2017- June 2018 Case Western Reserve University, MetroHealth Hospital, Cleveland, OH Louis V. Stokes Veterans Affairs Hospital, Cleveland, OH Cleveland Clinic Foundation, Cleveland, OH Spinal Cord Injury Fellow

July 2014- June 2017 Mercy Medical Center, Rockville Centre, NY Burke Rehabilitation Hospital, White Plains, NY St. Mary’s Children’s Hospital, Bayside, Queens, NY Physical Medicine and Rehabilitation Resident

June 2013- June 2014 Long Beach Medical Center/South Nassau Communities Hospital, Long Beach/Oceanside, NY Traditional Rotating Intern

August 2009- May 2013 University of Medicine and Dentistry of New Jersey- School of Osteopathic Medicine now Rowan University - School of Osteopathic Medicine, Stratford, NJ Doctor of Osteopathic Medicine, DO

August 2007- July 2009 Columbia University, New York, NY Masters of Public Health, Health Policy and Management, MPH Masters of Science, Nutrition, MS

September 2002 - June 2006 The University of Chicago, Chicago, IL Bachelor of Arts in Biology with a Specialization in Endocrinology, BAThis author has no relevant disclosures.Patricia Kiefer, MSN, RN, ACCNS-AGLouis Stokes Veterans Administration Medical Center Bio:Patricia L. Kiefer, MSN, RN, ACCNS-AG, is currently an adjunct professor for the Chamberlain College of Nursing and the Clinical Nurse Specialist on the Spinal Cord Injury/Disorder Unit at the Louis Stokes Veterans Administration Medical Center (LSVAMC) in Cleveland Ohio. After completing her Bachelors of Science in nursing from the University of Akron's College of Nursing in 2004, Patricia worked as a critical care nurse in the medical, cardiac, and surgical intensive care units. She then went on to complete her Masters in Nursing with a focus in Adult

Gerontology and was certified as an Acute Care Clinical Nurse Specialist in 2014. Patricia serves on the Medical Centers Diabetic Advisory Board, is a Board member of the Cuyahoga County Organization of Disaster Preparedness and is the co-chair for the Patient Education Council and the Nursing Peer Review committee. Ms. Kiefer is a member on several other committees and facilitates performance improvement projects to close or alleviate current gaps in care on the Spinal Cord Injury Unit and with in the medical center. She has presented at the Clinical Nurse Specialist Conference on preventing device related Hospital Acquired Pressure Injuries (HAPI) post-tracheotomy and is currently working on a performance improvement project to reduce urinary tract infections in the long term care spinal cord injury patient population which was presented as a poster presentation at the Academy of Spinal Cord Injury Professionals. Education:University of Akron College of Nursing, Akron 2004/ Bachelor of Science of Nursing

University of Akron Graduate School of Nursing, Adult/Gerontological Health Nursing Clinical Nurse Specialist, Akron 2014/ Master of Science in NursingThis author has no relevant disclosures.Ginger Willoughby, RNLouis Stokes Veterans Administration Medical Center This author has no relevant disclosures.M. Kristina Henzel, MD, PhDLouis Stokes Veterans Administration Medical Center This author has no relevant disclosures.

111Vitamin supplement use in people with spinal cord injury: Results from the FRASCI studyThursday, May 03, 2018 09:30 AM - 10:30 AMLearning Objectives:Attendees will be able to describe vitamin and supplement use reported by people with SCI.

Participants:Coker J, Morse L, Charlifue SCraig Hospital , Englewood , CO, USJennifer Coker, MPHCraig Hospital Bio:Ms. Coker has worked in the field of traumatic spinal cord injury (SCI) since 1997. She obtained a Master of Public Health from the Rollins School of Public Health at Emory University in May 2001, where she won the James W Alley Award for Outstanding Service to Disadvantaged Populations, and is currently a PhD student in the Clinical Sciences program at the University of Colorado-Anschutz Medical Campus. She has presented research at national conferences of ASIA, the American Association of Spinal Cord Injury Psychologists and Social Workers (now ASCIP), the American Public Health Association, and the American Psychological Association. In addition, Ms. Coker has won several awards for research presentations and publications. She

has been a Research Associate at Craig Hospital since April 2012 and works primarily with the SCI Model Systems (SCIMS) projects. Ms. Coker is the PI for the Craig H Neilsen Foundation funded project, A Bridge from Rehabilitation to Real-World: Reinventing Yourself after SCI, the SCIMS module, Utilization of Complementary and Integrative Healthcare to Treat Pain in People with SCI, and Co-PI for a NIDILRR-funded project, A Multi-site Randomized Controlled Trial of an Intervention to Improve Outcomes after Spinal Cord Injury.Education:Berry College (Mt Berry, GA), BA 1997, Psychology & Child Development

Rollins School of Public Health, Emory University (Atlanta, GA), MPH 2001, Behavioral Health & Education

Clinical Science Graduate Program, University of Colorado-Anschutz Medical Campus (Aurora, CO), PhD in progress, Clinical InvestigationsThis author has the following disclosures:

Research Support Other (see below)

Research Support: NIDILRR (90SI5015)

Other-Employment: Craig Hospital, Englewood, CO; Medical University of South Carolina, Charleston, SC

Other-Volunteer: Cycle of Hope Board of Directors (member)Leslie Morse, DOCraig Hospital This author has the following disclosures:

Research Support Other (see below)

Research Support: NICHD (R21HD057030 and R21HD057030‐ 02S1), National Institute of Arthritis & Musculoskeletal & Skin Diseases (1R01AR059270‐01), and NIDILRR (90SI5015).

Other-Employment: Craig Hospital, Englewood, COSusan Charlifue, PhDCraig Hospital This author has the following disclosures:

Research Support Other (see below)

Research Support: NIDILRR (90SI5015)

Other-Employment: Craig Hospital, Englewood, CO

112An in-depth analysis of the age profile of people sustaining spinal cord injury in Ireland

Thursday, May 03, 2018 09:30 AM - 10:30 AMLearning Objectives:To improve understanding of SCI epidemiology outside of North America

Participants:1Smith E, 2Fitzpatrick P1National Rehabilitation Hospital , Dublin , , Ireland; 2University College Dublin , Dublin , , IrelandEimear Smith, MB, MSc, MD, FRCPINational Rehabilitation Hospital Bio:Consultant in Rehabilitation Medicine at the National Rehabilitation & Mater Misericordiae University Hospitals, Dublin; Medical Director of the Spinal Cord System of Care programme at the National Rehabilitation Hospital. Member of the ASIA education committee; current Health Research Board (Ireland) grant-holder. Education:Medical Degree (MB, BCh, BAO) - University College Dublin, 1991 - 1997 MSc (Sports & exercise Medicine) Trinity College Dublin, 2001 Membership of Royal College of Physicians of Ireland, 2001 Degree of Doctor of Medicine (MD) - Higher research degree, University College Dublin, 2009 Fellowship of Royal College of Physicians of Ireland, 2015This author has the following disclosures:

Research SupportHealth Research Board (Ireland) grant holder - principal investigatorPatricia Fitzpatrick, MB, BCh, BAO, MD, FRCPI, MPH, FFPHMIUniversity College Dublin Bio:.Education:.This author has the following disclosures:

Research SupportHealth Research Board (Ireland) grant holder - co investigator

113Statin Therapy as Potential Treatment for Endocrine Metabolic Disease in Individuals with Chronic Spinal Cord Injury: A Cross-Sectional StudyThursday, May 03, 2018 09:30 AM - 10:30 AMLearning Objectives:1) To review the prevalence of EMD risk and; 2) To describe the therapeutic potential of statin therapy to increase distal femur bone mass and decrease EMD risk among patients with motor complete SCI.

Participants:1Miyatani M, 1Alavinia S, 2Giangregorio L, 1Blencowe L, 3Anderson-Erisman K, 4Cheung A, 3Nash M, 1Craven B1Toronto Rehabilitation Institute-Uhn , Toronto , Ontario, Canada; 2University of Waterloo , Waterloo , Ontario, Canada; 3University of Miami Miller School of Medicine , Miami , Florida, USA; 4Departments of Medicine and Joint Department of Medical Imaging, University Health Network , Toronto , Ontario, CanadaMasae Miyatani, PhDToronto Rehabilitation Institute-Uhn Bio:Dr. Miyatani is a Clinical Research Coordinator in the Neural Engineering and Therapeutics Team, Toronto Rehabilitation Institute-UHN. Since completing her PhD training in Kinesiology in 2003 at the University of Tokyo, Japan, the substantial portion of her work has revolved around cardiovascular, skeletal muscle health and how body composition affects human health in the general population and among people living with disabilities. Currently, Dr. Miyatani's clinical research focuses on cardiovascular health in people with chronic spinal cord injury. Specifically, she has been studying arterial stiffness and body composition as a potential screening tool for cardiovascular health and the efficacy of exercise and marketed drug interventions on arterial stiffness and body composition in SCI. Currently, she is coordinating a Health Canda approved study exploring the use of statins for the modification of bone mass and cardiometabolic disease risk in people with SCI (RoBaCO Trial NCT#03113994 ). Education:1992 Tokyo Women’s College of Physical Education-B. Ed. Physical Education

1997 Nippon Sport Science University - MS Physical Education

2000 University of Tokyo- MS Kinesiology

2003 University of Tokyo-PhD Kinesiology This author has no relevant disclosures.S. Mohammad Alavinia, MD, PhDToronto Rehabilitation Institute-Uhn This author has no relevant disclosures.Lora Giangregorio, PhDUniversity of Waterloo This author has no relevant disclosures.Lindsie Blencowe, MScToronto Rehabilitation Institute-Uhn This author has no relevant disclosures.Kim Anderson-Erisman, PhDUniversity of Miami Miller School of Medicine This author has no relevant disclosures.

Angela Cheung, MD, PhDDepartments of Medicine and Joint Department of Medical Imaging, University Health Network This author has no relevant disclosures.Mark Nash, PhDUniversity of Miami Miller School of Medicine This author has the following disclosures:

Research SupportResearch Grant: Craig H Neilsen Foundation (#350642)B. Catharine Craven, Md, MScToronto Rehabilitation Institute-Uhn This author has the following disclosures:

Research SupportResearch Grant: Canadian Institutes for Health Research (grant no. 86521), Rick Hansen Institute (grant no. 2012-03), Craig H Neilsen Foundation (#350642)

114Prevalence of vitamin D deficiency in patients with spinal cord injury: a cross sectional study. Thursday, May 03, 2018 09:30 AM - 10:30 AMLearning Objectives:This study aimed to (1) evaluate 25-hydroxyvitamin D concentrations in patients with spinal cord injury admitted to a UK SCI centre over four seasons and (2) to assess the characteristics of vitamin D deficiency.

Participants:1Gainullina I, 1Rouse A, 2Hirani S, 1Saif M, 1Graham A, 1Wong S1National Spinal Injuries Centre, Stoke Mandeville Hospital , Aylesbury , , United kingdom; 2City, University of London , London , , United kingdomIrina Gainullina, MDNational Spinal Injuries Centre, Stoke Mandeville Hospital Bio:Irina Gainullina is Speciality Docotor in the National Spinal Injuries Centre, Stoke Mandeville Hospital Education:MDThis author has no relevant disclosures.Alex Rouse, MDNational Spinal Injuries Centre, Stoke Mandeville Hospital This author has no relevant disclosures.Shashi Hirani, PhDCity, University of London

This author has no relevant disclosures.Mofid Saif, MD., FRCP., FRCSNational Spinal Injuries Centre, Stoke Mandeville Hospital This author has no relevant disclosures.Allison Graham, MD., FRCPNational Spinal Injuries Centre, Stoke Mandeville Hospital This author has no relevant disclosures.Samford Wong, MSc (Med Sci)., PhD., RDNational Spinal Injuries Centre, Stoke Mandeville Hospital Bio:Samford Wong is NSIC Dietetic Lead in Research / Lead Dietitian, National Spinal Injuries Centre, Stoke Mandeville Hospital Department of Nutrition and Dietetics, Stoke Mandeville Hospital, Buckinghamshire Healthcare NHS Trust, Aylesbury HP21 8AL; Tel: 01296 315775 Education:Education: 2004: BSc (Hons)., RD; 2006: MSc (Med Sci); 2010; Dip Adv Diet: 2011; 2012: MPhil / PhD PTLLS: 2013; CMS: 2014This author has the following disclosures:

Research SupportGrant from Yakult Honsha

115Prevalence of dyslipidaemia in patients with spinal cord injury: a cross-sectional study. Thursday, May 03, 2018 09:30 AM - 10:30 AMLearning Objectives:This study aims to (1) assess the uptake of lipid profile screening (LPS); (2) describe the prevalence of dyslipidaemia using ATPIII guideline and 10-years CVD risk using QRISK2; (3) describe the characteristics of elevated CVD risk in patients with SCI.

Participants:1Iova G, 1Rouse A, 2Lari S, 3Ussef I, 3Jamous A, 1Graham A, 1Wong S1National Spinal Injuries Centre, Stoke Mandeville Hospital , Aylesbury , , United kingdom; 2Southport & Ormskirk Hospital , Southport , , United kingdom; 3Royal Buckinghamshire Hospital , Aylesbury , , United kingdomGeorgiana Iova, MDNational Spinal Injuries Centre, Stoke Mandeville Hospital

Bio:Georgiana Ivoa is Specialist Doctor in the National Spinal Injuries Centre at Stoke Mandeville Hospital.Education:MDThis author has no relevant disclosures.Alex Rouse, MDNational Spinal Injuries Centre, Stoke Mandeville Hospital This author has no relevant disclosures.Salman Lari, MRCSSouthport & Ormskirk Hospital This author has no relevant disclosures.Ibrahim Ussef, MDRoyal Buckinghamshire Hospital This author has no relevant disclosures.Ali Jamous, MDRoyal Buckinghamshire Hospital This author has no relevant disclosures.Allison Graham, MD., FRCPNational Spinal Injuries Centre, Stoke Mandeville Hospital This author has no relevant disclosures.Samford Wong, MSc (Med Sci)., PhD., RDNational Spinal Injuries Centre, Stoke Mandeville Hospital Bio:Samford Wong is NSIC Dietetic Lead in Research / Lead Dietitian, National Spinal Injuries Centre, Stoke Mandeville Hospital Department of Nutrition and Dietetics, Stoke Mandeville Hospital, Buckinghamshire Healthcare NHS Trust, Aylesbury HP21 8AL; Tel: 01296 315775 Education:Education: 2004: BSc (Hons)., RD; 2006: MSc (Med Sci); 2010; Dip Adv Diet: 2011; 2012: MPhil / PhD PTLLS: 2013; CMS: 2014This author has the following disclosures:

Research SupportResearch grant form Yakult Honsha

116Normalization of Blood Pressure with Spinal Cord Epidural Stimulation after Severe Spinal Cord Injury

Thursday, May 03, 2018 09:30 AM - 10:30 AMLearning Objectives:To discuss the effects of targeted scES for cardiovascular function (CV-scES) in individuals with severe SCI who suffer from chronic hypotension.

Participants:1Harkema S, 2Wang S, 1Angeli C, 3Chen Y, 4Boakye M, 4Ugiliweneza B, 5Hirsch G1Frazier Rehab Institute; University of Louisville Kentucky Spinal Cord Injury Research Center , Louisville , Kentucky, United states; 2Department of Neurological Surgery , Louisville , Kentucky, United states; 3University of Louisville Kentucky Spinal Cord Injury Research Center , Louisville , Kentucky, United states; 4University of Louisville Department of Neurosurgery , Louisville , Kentucky, United states; 5University of Louisville School of Medicine , Louisville , Kentucky, United statesSusan Harkema, PhDFrazier Rehab Institute; University of Louisville Kentucky Spinal Cord Injury Research Center Bio:Dr. Susan J. Harkema PhD, Professor holds the Owsley B. Frazier Rehabilitation Chair in Neurological Surgery and is the Associate Director of the Kentucky Spinal Cord Injury Research Center at the University of Louisville. She is the Director of Research at Frazier Rehab Institute and is Director of the NeuroRecovery Network that provides standardized activity-based therapies for individuals with spinal cord injury at seven national rehabilitation centers in the United States. Her research focuses on neural plasticity of spinal networks and recovery of function after spinal cord injury.

Dr. Harkema has published numerous scholarly articles on her research and has received several honors and awards throughout her career. In 2007, the National Spinal Cord Injury Association nominated her into the SCI Hall of Fame for Achievement in Research in Quality of Life, and Dr. Harkema was a co-recipient of the Reeve-Irvine Research Medal, awarded to individuals who have made critical contributions to promoting repair of the damaged spinal cord and recovery of function.

Dr. Harkema earned her Bachelor of Science and PhD from Michigan State University and conducted her postdoctoral fellowship in neurophysiology at the University of California, Los Angeles. Education:Dr. Harkema earned her Bachelor of Science and PhD from Michigan State University and conducted her postdoctoral fellowship in neurophysiology at the University of California, Los Angeles. This author has no relevant disclosures.Siqi Wang, Department of Neurological Surgery This author has no relevant disclosures.Claudia Angeli, PhDFrazier Rehab Institute; University of Louisville Kentucky Spinal Cord Injury Research Center This author has no relevant disclosures.

Yangsheng Chen, University of Louisville Kentucky Spinal Cord Injury Research Center This author has no relevant disclosures.Maxwell Boakye, MDUniversity of Louisville Department of Neurosurgery This author has no relevant disclosures.Beatrice Ugiliweneza, PhDUniversity of Louisville Department of Neurosurgery This author has no relevant disclosures.Glenn Hirsch, MD, MHS, FACCUniversity of Louisville School of Medicine This author has no relevant disclosures.

117Personality, high-risk behaviors, and the elevated risk of unintentional deaths related to drug poisoning among those with spinal cord injuryThursday, May 03, 2018 09:30 AM - 10:30 AMLearning Objectives:To identify risk factors for unintentional death due to drug poisoning and to differentiate these factors from those related to other causes of mortality.

Participants:Krause J, Cao Y, DiPiro NMedical University of South Carolina , Charleston , SC, United statesJames Krause, PhDMedical University of South Carolina This author has the following disclosures:

Research SupportUS Department of Health and Human Services Administration for Community Living, NIDILRR grant numbers 90RT5003 AND 90IF0066. Yue Cao, PhDMedical University of South Carolina Bio:Yue Cao holds the rank of Assistant Professor in the College of Health Professions at the Medical University of South Carolina. He graduated from the joint program (PhD in Medical Sociology, and MSPH in Epidemiology) at the University of Alabama at Birmingham. He has authored or co-authored 25 publications and 31 presentations in national or international conferences in the past 5 years. Dr. Cao’s research interests focus on health disparities, Epidemiology of spinal cord injury, psychosocial perspectives of rehabilitation process, migration and health study.Education:August 2011 MSPH, Epidemiology

University of Alabama at Birmingham, USA

May 2010 PhD, Medical Sociology University of Alabama at Birmingham, USA

July 2003 BA, English Nanjing Normal University, China This author has the following disclosures:

Research SupportUS Department of Health and Human Services Administration for Community Living, NIDILRR grant numbers 90RT5003 AND 90IF0066. Nicole DiPiro, PhDMedical University of South Carolina This author has the following disclosures:

Research SupportUS Department of Health and Human Services Administration for Community Living, NIDILRR grant numbers 90RT5003 AND 90IF0066.

118Lifetime Prevalence Comparison of Chronic Health Conditions between Spinal Cord Injury Cohorts and the General PopulationThursday, May 03, 2018 09:30 AM - 10:30 AMLearning Objectives:Identify the lifetime prevalence of 11 chronic health conditions among people with spinal cord injury, and find the difference between them and people in the general population.

Participants:Cao Y, Krause JMedical University of South Carolina , Charleston , SC, United statesYue Cao, MSPH, PhDMedical University of South Carolina Bio:Yue Cao, PhD, MSPH holds the rank of Assistant Professor in the Department of Health Science and Research at the Medical University of South Carolina. He graduated from the joint program (PhD in Medical Sociology, and MSPH in Epidemiology) at the University of Alabama-Birmingham. He previously worked at the National Spinal Cord Injury Statistical Center, where he completed his Postdoc training. His research interests focus on Epidemiology of Spinal Cord Injury, health disparities, and psychosocial perspectives of rehabilitation. In the past four years, he has authored or co-authored 19 publications in peer-reviewed journals and 22 presentations in national or international conferences.

Education:PhD in Medical Sociology MSPH in EpidemiologyThis author has the following disclosures:

Research SupportAdministration for Community Living, NIDILRR grant 90IF0070James Krause, PhDMedical University of South Carolina This author has the following disclosures:

Research SupportAdministration for Community Living, NIDILRR grant 90IF0070

119Development and Implementation of a Universal Standing and Walking Assessment Tool (SWAT) for Spinal Cord Injury during the Rehabilitation Process Thursday, May 03, 2018 09:30 AM - 10:30 AMLearning Objectives:1) Understand the development and implementation process of a Universal Standing and Walking Assessment Tool (SWAT) for Spinal Cord Injury during the Rehabilitation Process.

Participants:1Walden K, 2Verrier M, 3Mussleman K, 4Gagnon D, 5Lemay J, 6Guy K1Rick Hansen Institute , Vancouver , BC, Canada; 2Departments of Physical Therapy, Rehabilitation Science, Institute of Medical Science and Physiology, Faculty of Medicine University of Toronto and University Heath Network-Toronto Rehabilitation Institute, Lyndhurst Centre , Toronto , ON, Canada; 3University Health Network , Toronto , ON, Canada; 4Université De Montréal, Centre De Recherche Interdisciplinaire En Réadaptation Du Montréal Métropolitain (Crir), Institut De Réadaptation Gingras- Lindsay-De-Montréal , Montreal , QC, Canada; 5Institut De Readaptation Gingras-Lindsay-De-Montreal , Montreal , QC, Canada; 6Toronto Rehabilitation Institute , Toronto , ON, CanadaKristen Walden, PTRick Hansen Institute Bio:Kristen Walden is currently the National Clinical Liaison for the Rick Hansen Institute (RHI) and a physiotherapist at Vancouver Coastal Health. The focus of her research involvement and clinical practice has been in the area of spinal cord injury (SCI). Clinically, she has practiced in the area of SCI for over 15 years, working with individuals in intensive care, acute care, as well as both inpatient and outpatient rehabilitation settings. Kristen is currently working on the Rick Hansen Spinal Cord Injury Registry (RHSCIR); a national Canadian initiative at 31 acute care and rehabilitation facilities. RHSCIR aims to collect standardized data on individuals who sustain traumatic spinal cord injuries, as well as link clinicians, researchers, and health care administrators with the goal of improving both research and clinical practice in SCI. Kristen led the development of a freely available web-based International Standards for Neurological

Classification of SCI (ISNCSCI) algorithm and provides clinical training on the use of the ISNCSCI according to the guidelines provided by ASIA for clinicians across Canada. To date she has provided training to over 250 clinicians. Her interests are in supporting best practice implementation into clinical practice.Education:University of British Columbia (Vanouver, BC), BscPT 1997-2000 This author has no relevant disclosures.Molly Verrier, Dip(P&OT), MHScDepartments of Physical Therapy, Rehabilitation Science, Institute of Medical Science and Physiology, Faculty of Medicine University of Toronto and University Heath Network-Toronto Rehabilitation Institute, Lyndhurst Centre This author has no relevant disclosures.Kristin Mussleman, BScPT, MSc, PhDUniversity Health Network This author has no relevant disclosures.Dany Gagnon, BScPT, MSc, PhDUniversité De Montréal, Centre De Recherche Interdisciplinaire En Réadaptation Du Montréal Métropolitain (Crir), Institut De Réadaptation Gingras- Lindsay-De-Montréal This author has no relevant disclosures.Jean Francois Lemay, MPT, PhDInstitut De Readaptation Gingras-Lindsay-De-Montreal This author has no relevant disclosures.Kristina Guy, MScToronto Rehabilitation Institute This author has no relevant disclosures.

120Long-term functional outcome in patients with acquired infections after acute spinal cord injury.Thursday, May 03, 2018 09:30 AM - 10:30 AMLearning Objectives:Outcome modifying factor

Participants:1Schwab J, 2Kopp M, 2Waltzlawick R, 3Martus P, 4Chen Y, 4DeVivo M1The Ohio State University , Columbus , OH, USA; 2Charite - School of Medicine Berlin , Berlin , , Germany; 3Institute for Medical Biometry, University of Tuebingen , Tuebingen , , Germany; 4University of Alabama , Birmingham , Alabama, USAJan Schwab, MD PhDThe Ohio State University Bio:2016 - ongoing Program Director for the Ohio Regional Spinal Cord Injury Model System 2015 - ongoing Director Spinal Cord Injury Division – Neurology

11/2014 – ongoing Professor of Neurology and Neuroscience, W.E. Hunt & C.M. Curtis Chair in Neuroscience, Wexner Medical Center at The Ohio State University. 5/2013 – 10/2014 Attending physician, Spinal Cord Injury Dept., Trauma Hospital Berlin. 12/2012 Board Certification in “Neurology”. 2009 Faculty-Member of the DFG-research training school, 1258 “Neuroinflammation” 07/2007 Professor, Tuebingen University, School of Medicine. 01/2007 - ongoing Physician and Group Leader “Spinal Cord Injury Research”, Department of Neurology & Experimental Neurology, Charité Medical School, Berlin. Education:02/2005 - 04/2006 Research Fellow at Brigham and Women`s Hospital, Harvard Medical School, Boston, U.S.A. 11/2004 - ongoing Medical & Scientific Director of the Wings for Life Spinal Cord Foundation. 02/2004-01/2005 Research Fellow at the CNRS 7102, Université P. & M. Curie, Paris, France. 2004 Habilitation/Venia Legendi “Experimental Neuropathology” 2003 Dissertation (Doctor rerum naturalium, Dr. rer. nat., Ph.D.) 07/2000 - 01/2004 Fellow – Institute of Brain Research, Tuebingen University, School of Medicine. 12/2000 - 03/2003 Neural and Behavioral Sciences, International Max-Planck Research School, University of Tuebingen”. 2000 Dissertation (Doctor medicinae, Dr. med., MD). 01/1999 - 06/2000 Resident Physician “Arzt im Praktikum (AiP)”: Institute of Brain Research, Tuebingen University, School of Medicine. Full Approbation. This author has the following disclosures:

Research SupportMarcel Kopp, MDCharite - School of Medicine Berlin Bio:is not a presenting author on abstractEducation:is not a presenting author on abstractThis author has the following disclosures:

Research SupportRalf Waltzlawick, MDCharite - School of Medicine Berlin Bio:is not a presenting author on abstractEducation:is not a presenting author on abstractThis author has the following disclosures:

Research SupportPeter Martus, PhDInstitute for Medical Biometry, University of Tuebingen Bio:is not a presenting author on abstract

Education:is not a presenting author on abstractThis author has the following disclosures:

Research SupportYuYing Chen, MD PhDUniversity of Alabama Bio:is not presenting author of abstractEducation:is not presenting author of abstractThis author has the following disclosures:

Research SupportMichael DeVivo, PhDUniversity of Alabama Bio:is not presenting author of an abstractEducation:is not presenting author of an abstractThis author has the following disclosures:

Research Support

121Multiple Chronic Conditions and Health Related Behaviors among Persons with Spinal Cord InjuryThursday, May 03, 2018 09:30 AM - 10:30 AMLearning Objectives:Identify the prevalence of multiple chronic conditions among people with spinal cord injury, and assess the impact of health-related behaviors on them.

Participants:Cao Y, Krause JMedical University of South Carolina , Charleston , SC, United statesYue Cao, MSPH, PhDMedical University of South Carolina Bio:Yue Cao, PhD, MSPH holds the rank of Assistant Professor in the Department of Health Science and Research at the Medical University of South Carolina. He graduated from the joint program (PhD in Medical Sociology, and MSPH in Epidemiology) at the University of Alabama-Birmingham. He previously worked at the National Spinal Cord Injury Statistical Center, where he completed his Postdoc training. His research interests focus on Epidemiology of Spinal Cord Injury, health disparities, and psychosocial perspectives of rehabilitation. In the past four years, he has authored or co-authored 19 publications in peer-reviewed journals and 22 presentations in national or international conferences.

Education:PhD in Medical Sociology MSPH in EpidemiologyThis author has the following disclosures:

Research SupportAdministration for Community Living, NIDILRR grant 90IF0070James Krause, PhDMedical University of South Carolina This author has the following disclosures:

Research SupportAdministration for Community Living, NIDILRR grant 90IF0070

122The effects of older age on the initial spine care of patients with acute spine traumaThursday, May 03, 2018 09:30 AM - 10:30 AMLearning Objectives:Discuss the effects of old age on the costs of management of individuals with acute spine trauma.

Participants:1Furlan J, 2G M, 1Craven B1Lyndhurst Centre, Toronto Rehabilitation Institute & University of Toronto , Toronto , ON, Canada; 2Toronto Western Hospital and University of Toronto , Toronto , ON, CanadaJulio Furlan, MD, LLB, MBA, PhD, MSc, FRCPCLyndhurst Centre, Toronto Rehabilitation Institute & University of Toronto Bio:Julio C. Furlan, MD, LLB, MBA, PhD, MSc, FRCPC, is a staff neurologist and a Clinician Investigator in the Division of Physical Medicine and Rehabilitation and the SCI Rehabilitation Program at the Lyndhurst Centre, Toronto Rehabilitation Institute, University Health Network, and an Assistant Professor in the Department of Medicine, Division of Physical Medicine and Rehabilitation, University of Toronto. He is a trained head and neck surgeon from Brazil, who holds a MBA degree in Health Administration, an MSc degree in Clinical Epidemiology, and a PhD degree in Neuroanatomy. In the past, Dr. Furlan has worked as an Associate Research Scientist in the Department of Genetics and Development, Toronto Western Research Institute, University Health Network from 2007 to 2012. Dr. Furlan has also been an Adjunct Scientist at Toronto Rehabilitation Institute, University Health Network from 2009-2016, inclusive. He recently completed five years of residency training in Adult Neurology at University of Toronto in June 2014. Most recently, he completed a two-year clinical fellowship in Neurorehabilitation and Neural Repair at Toronto Rehabilitation Institute and the University of Toronto in June 2016. Dr Furlan´s research has been focused on outcome measures (including clinical assessments, neuroimaging analysis, and neurophysiological assessments) and predictors of outcome (including sex and age) after traumatic and non-traumatic spinal cord injury. In addition he has interest and expertise in autonomic dysfunction after spinal cord injury and economic analyses. Dr. Furlan has received 43 awards over the past 15 years. He has had research funding

support from Christopher and Dana Reeve Foundation, Wings for Life Research Foundation, Rick Hansen Foundation, and Cervical Spine Research Society.Education:University of São Paulo (São Paulo, Brazil), M.D. (1983-1988), Medicine University of São Paulo (São Paulo, Brazil), Residency (1989-1991), General Surgery University of São Paulo (São Paulo, Brazil), Residency (1991-1992), Preventive Medicine & Healthcare Systems University of São Paulo, (São Paulo, Brazil), Residency (1992-1994), Head and Neck Surgery Mackenzie University (São Paulo, Brazil), LL.B. (1994-1999), Law São Paulo Business School, Getúlio Vargas Foundation (São Paulo, Brazil), M.B.A. (1994-1999), Healthcare System and Hospital Administration University of São Paulo (São Paulo, Brazil), Ph.D. (1994-1999), Surgical Neuroanatomy University of Toronto (Toronto, Ontario, Canada), M.Sc. (2004-2006), Clinical Epidemiology Toronto Western Hospital, University Health Network (Toronto, Ontario, Canada), Research Fellowship (2003-2007), Spinal Cord Research University of Toronto (Toronto, Ontario, Canada), Residency (2009-2014), Neurology University of Toronto (Toronto, Ontario, Canada), Clinical Fellowship (2014-2016), Neurorehabilitation and Neural Repair This author has no relevant disclosures.Michael G, MD, PhD, FRCSCToronto Western Hospital and University of Toronto Bio:Dr. Fehlings, MD, PhD, is the Vice Chair Research for the Department of Surgery at the University of Toronto (UofT) and Head of the Spinal Program at Toronto Western Hospital, University Health Network. Dr. Fehlings is a Professor of Neurosurgery at UofT, holds the Gerry and Tootsie Halbert Chair in Neural Repair and Regeneration, is a Scientist at the McEwen Centre for Regenerative Medicine, a McLaughlin Scholar in Molecular Medicine, and is the Co-Director of the newly formed UofT Spine Program. After receiving his Medical degree from the UofT in 1983, he went on to complete his PhD in neuroscience at the U of T (1989). He then completed a clinical fellowship and postdoctoral research fellowship at the New York University Medical Center. He is a Fellow of the American College of Surgeons and a Fellow of the Royal College of Surgeons of Canada. He is the current Chair of the Spinal Cord Injury Knowledge Forum (AOSpine International), Chairman of the AOSpine International Outcome & Clinical Research Committee, President of the International Neurotrauama Society and past President of the Cervical Spine Research Society. He has had research funding support from multiple agencies such as the Wings for Life Spinal Cord Research Foundation, the Cervical Spine Research Society, AOSpine North America, the Heart and Stroke Foundation of Ontario, the Craig H. Neilsen Foundation, the Canadian Institutes of Health Research, the Christopher Reeve Foundation, the Ontario Neurotrauma Foundation, the Rick Hansen Institute, and Paralyzed Veterans of America. Dr. Fehlings combines an active clinical practice in complex spinal surgery with a translationally oriented research program focused on discovering novel treatments for the injured brain and spinal cord. This is reflected by the publication of 790 peer-reviewed articles (h-index 79) chiefly in the area of central nervous system injury and complex spinal surgery. Dr. Fehlings leads a multi-disciplinary team of researchers that is examining the application of stem cells, nanotechnology and tissue engineering for central nervous system repair and regeneration. Clinically, he recently led the international effort to develop clinical practice guidelines for

degenerative cervical myelopathy and traumatic spinal cord injury (SCI). Furthermore, he has been involved in a number of international clinical trials such as the examination of timing for decompressive surgery following SCI and the use of riluzole as a neuroprotective drug in patients with SCI. Dr. Michael Fehlings has received numerous prestigious awards including the Gold Medal in Surgery from the Royal College of Physicians and Surgeons, nomination to the Who’s Who list of the 1000 most influential scientists of the 21st century, the Lister Award in Surgical Research, the Leon Wiltse Award from the North American Spine Society for excellence in leadership and/or clinical research in spine care, the Reeve-Irvine Research Medal in SCI, and the Golden Axon Leadership Award. In 2013, Dr. Fehlings was honoured with the Queen Elizabeth II Diamond Jubilee Medal presented to him by the Honourable Stephen Harper. In 2014, Dr. Fehlings was elected to the Fellowship of the Royal Society of Canada and to the Canadian Academy of Health Sciences. Dr. Fehlings is active in many medical societies and journal editorial boards including Journal of Neurosurgery: Spine (Past-Chairman Editorial Board), Journal of Neurotrauma (Editor, Special Topics), Neurosurgery (Associate Editor) and Spine where he holds the position of Deputy Editor.

Education:University of Toronto (Toronto, ON, CAN) MD 1983 Medicine

University of Toronto (Toronto, ON, CAN) PhD 1989 Neuroscience

New York University Medical Center (New York, NY, USA) Postdoctoral Research Fellow January 1991- June 1991 Neurosurgery

New York University Medical Center (New York, NY, USA) Clinical Fellow July 1991-June 1992 Neurosurgery This author has no relevant disclosures.Beverly Craven, BA, MD, MSc, FRCPCLyndhurst Centre, Toronto Rehabilitation Institute & University of Toronto Bio:B. Catharine (Cathy) Craven, BA, MD, MSc, FRCPC is the Medical Lead of the Toronto Rehab Lyndhurst Centre Spinal Cord Rehabilitation Program and a Senior Scientist in the Neural Engineering and Therapeutics Team at Toronto Rehab’s Lyndhurst Centre within University Health Network. Dr. Craven is an Associate Professor in the Department of Medicine, Division of Physical Medicine and Rehabilitation, and Institutes of Rehabilitation Science and Health Policy Management and Evaluation at the University of Toronto, Canada. After completing a BA in Kinesiology at York University, Dr. Craven completed her Medical training and residency in Physical Medicine and Rehabilitation at McMaster University, and then completed training as a Clinical Scholar in Spinal Cord injury and a Master’s in Clinical Epidemiology at the University of Toronto. Dr. Craven has served as the Co- Chair of the 1st through 7th National SCI conference ( www.SCI2017.com ) in Canada, Scientific Officer for the Canadian Association of Physical Medicine and Rehabilitation, Chair of the Rick Hansen Institute CARE Committee, Inaugural Chair of the newly founded Canadian Spinal Cord Injury – Rehabilitation Association. Dr. Craven holds research funding from the Craig H. Nielsen Foundation, Canadian Institute of Health Research, Rick Hansen Institute, Ontario Neurotrauma Foundation and Physician Services Inc. Dr Craven was the 2017 CAPMR Award of Merit Recipient. Dr Craven’s current

research focuses on reducing Endocrine Metabolic disease (fracture, heart disease, and diabetes) risk after spinal cord injury and enhancing health services for patients with SCI in Canada by 2020 through leadership of the E-Scan Atlas (www.idapt.com/research/E-scan )and SCI-HIGH projects (https://sites.google.com/view/sci-high/home). Dr Craven has published over 125 papers on related topics. Education:York University (Ontario, Canada), BA (1989), Physical Education McMaster University (Ontario, Canada), MD (1994), Medicine McMaster University (Ontario, Canada), FRCPC (1998), Physiatry University of Toronto (Ontario, Canada), MSc (2007), Clinical Epidemiology This author has no relevant disclosures.

123Case ReportsThursday, May 03, 2018 09:30 AM - 10:30 AMLearning Objectives:To educate about the benefits in lower limb prosthesis in tetraplegics

Participants:1Pathak R, 1Pathak R, 2Dabai N, 3Recio A1Kennedy Krieger Institute , Baltimore , MD, USA; 2The Johns Hopkins University School of Medicine , Baltimore , Maryland, United states; 3The Johns Hopkins University School of Medicine, the International Center for Spinal Cord Injury at Kennedy Krieger Institute , Baltimore , Maryland, United statesRishi Pathak, MDKennedy Krieger Institute Bio:Rishi Pathak M.D. is a SCI fellow at the Kennedy Krieger Institute and Johns Hopkins University. He has completed his preliminary year in General Surgery at St. Josephs Hospital in Denver Colorado. With regard to residency he completed this at the Rehabilitation Institute of Michigan in Detroit, MI.Education:St Joseph's College (Patchogue, NY, BS 2004-2008 Biology St. Matthews University (Grand Cayman Island, BWI), MD 2009-2012 Medicine St. Josephs Hospitah (Denver, CO) 2013-2014 Prelim Year Rehabilitation institute of Michigan (Detroit, MI) PM&R Kennedy Krieger Institute/Johns Hopkins Fellowship SCI (Baltimore, MD) Current This author has no relevant disclosures.Rishi Pathak, MDKennedy Krieger Institute Bio:

“Hey Pathak, your of the dot type Indian variety right? Why don't you hit the library instead of my field because I guarantee you can crush textbooks better than you can open field tackle.” Not

the most motivating high school coach I’ve ever had; however, the words stuck with me. He thought that by discouraging me from playing football, I would quit and just leave team sports and resign myself to academia only. His words instead spurred me to push myself both as a team player in sports and in academics. I developed a personal philosophy and have stuck by it ever since; knowledge is potential and action is power with the eventual goal of being a team physician.

Whilst progressing through rotations both in medical school and residency it was not until my sports medicine rotation that I found my niche. In Physiatry I have been exposed to all aspects of injury, from accident to traumatic, and the multidisciplinary approach to treating each individual based on their specific needs. A team can consist of occupational and physical therapists, neuropsychologists, athletic trainers, and recreational therapists. With the intimate knowledge I have gained of musculoskeletal, spinal cord, traumatic brain, and pediatric injury from my other rotations, I can apply my skills to varying types of athletes. The additional training I have received of electrodiagnostics, ultrasound, and fluoroscopy has given me confidence and my skills have grown to the point that completing a sports medicine fellowship would aid in my becoming a more knowledgeable and well rounded a physician.

Physiatry is much more than signs and symptoms followed by treatment and discharge. There is a direct impact on the patient which can be appreciated immediately. Throughout the residency I was amazed at the amount of time and attention given to each and every patient and their family. Personally, I adore spending time with patients and families. The additional contact from all members of the team allowed for me to have better context in my treatment of the whole patient. During my time in the clinic , it was evident that the added personal connection the attending physicians conveyed throughout the recovery process aided in the building of lasting tools for the patient’s healing; something which I greatly admire. The ability to memorize and regurgitate diagnoses and treatment on exams makes a great physician, on paper. Does that however translate to real time interactive quality health care? Having the ability to retain knowledge is bountiful potential, yet having the ability to communicate that wealth of information to the patient and or team effectively, is both powerful and crucial.

The ability to help in regaining a patient’s ability to adaptively live independently was enriching as well as rewarding. Participating with the patients in the Sports Ability basketball tournaments and Bowling league was life altering for me. The multidisciplinary approach to a patient’s overall well-being was something that was congruent with my personal medical practice philosophy. I believe treatment should address not only the biological/physiological processes but the mechanical, social, psychological, and familial aspects as well. Sports medicine based physiatric practice encompasses all of the above, all the while taking into account the future social welfare of the patient by prescribing continued in or outpatient therapy and home health care if necessary in conjunction with school based therapies in the pediatric population.

Having slid off a roof and having to complete therapy myself, I realized how there are various aspects in play in terms of recovery. If I were to need continued therapy and adaptive equipment,

what that would mean to not only myself but my family? That thought process informs my judgement for prescribing treatment. Whether it is the inability to complete simple tasks or complete dependency on others, either can cause life to become burdensome for a patient and family. The ability to help in regaining a family’s ability to adaptively live independently was enriching as well as rewarding.

While meeting the rigorous demands of medical school and residency, I found that moving to a foreign country for basic sciences along with the consistent travel associated with the St. Matthew’s clinical and Rehabilitation Institute of Michigan curriculum were more challenging than anticipated. Although the need to regularly relocate in order to participate in my medical education proved difficult, I was able to overcome. I believe that this experience has helped me to become a more resilient and adaptable individual; all attributes I feel will aid me throughout my fellowship. My journey to and throughout medical school and a heavy inpatient/outpatient residency has equipped me with the tools to lead, communicate, travel, and teach which are essential attributes of a physician regardless of subspecialty. Given my life, work, and educational experiences in conjunction with a fellowship I feel as if I have the ability to treat all “athletes.” That spectrum consists of everyone including the weekend warrior, industrial athlete, as well as elite athletes of all ages.

I respect and value how sports medicine trained physiatrists work tirelessly to treat debilitating, life altering diseases of the musculoskeletal system. I want to continue building upon my knowledge of the clinical pathophysiology and rehabilitation needed to serve a diverse patient population. During my sports medicine rotation I witnessed, and wanted to contribute to, the strong lasting relationships physiatrists develop with their patients and families. I want to join a sports medicine fellowship program that matches my enthusiasm and excitement about learning; a program that encourages fellows to formulate theories and create research and quality improvement projects. My long-term goal is to work with an affiliated hospital system as part of the rehabilitation team while teaching residents and medical students both on and off the field. In closing, I am passionate and highly motivated to become a sports medicine physician. I am persevering, meticulous, respectful, open-minded, and hardworking. I look forward to being able to integrate knowledge from all the medical specialties that I have been involved in while practicing pediatric rehabilitation. This field of medicine will enable me to make a tremendous difference in patient care, one individual, in conjunction with their family, at a time.

Education:St. Joseph's College (Patchogue, NY) BS 2004-2008, Biology St. Matthews University (Grand Cayman Islands, BWI MD 2009-2012 Medicine Exempla Health (Denver, CO) Preliminary Surgical Intern 20013-200-14 Rehabilitation Institute of Michigan (Detroit, MI, PM&R Johns Hopkins/Kennedy Krieger Institute - Spinal Cord Fellow, Current This author has the following disclosures:Nicholas Dabai, DOThe Johns Hopkins University School of Medicine Bio:Nicholas S Dabai, D.O. is a Physical Medicine and Rehabilitation resident at Johns Hopkins School of Medicine. He completed medical school at the University of New England, College of

Osteopathic Medicine. Prior to starting his PMR residency, he completed his preliminary year in General Surgery at Harbor-UCLA Medical Center, Torrance, CA. Education:Johns Hopkins School of Medicine Physical Medicine and Rehabilitation Residency, July 2016 to current Post-Graduate Year II

Harbor UCLA Medical Center, Internship General Surgery Internship in General Surgery, June 2015 to June 2016 Post-Graduate Year I

University of New England College of Osteopathic Medicine Doctor of Osteopathic Medicine, May 2015

Boston University School of Medicine Master of Arts, Medical Sciences, January 2011

University of California, Davis Bachelor of Science, Biochemistry with Minor, Managerial Economics, June 2003This author has the following disclosures:Albert Recio, MD, RPT, PTRPThe Johns Hopkins University School of Medicine, the International Center for Spinal Cord Injury at Kennedy Krieger Institute Bio:I am currently a physician in the paralysis restoration program at the International Center for Spinal Cord Injury (ICSCI), and the Medical Director for the Aquatics Medicine Program at Kennedy Krieger Institute. I am also an Assistant Professor of Physical Medicine and Rehabilitation at The Johns Hopkins University School of Medicine.

Born in the Philippines, my medical career began first as a licensed physical therapist from 1990-1993 at the Sarah Bush Lincoln Health Center in Mattoon, Illinois. I then graduated cum laude in 1997 from the Perpetual Help College of Medicine in Biñan, Laguna. I did my internship training at the Perpetual Help Medical Center from 1997-1998 and completed my general internship at Jackson Park Hospital in Chicago, Illinois from 2002-2003. I did my residency in Physical Medicine and Rehabilitation at the Harvard Medical School/Spaulding Rehabilitation Hospital in Boston, Massachusetts from 2003-2006. From there, I completed a year-long clinical fellowship in spinal cord injury medicine at University of Washington/VA-Puget Sound Health Care System in Seattle, Washington in 2007.

Since 2010, I piloted the Virtual Sailing Simulator Research Program at Kennedy Krieger Institute which allows individuals with disabilities to participate in real time “ride on” virtual sailing. I have also researched adaptive sailing and how adapted recreational activity complements the rehabilitation process, enriches patients' lives and positively impacts outcome measures. Most recently, and keeping with the water theme, I am looking at the effectiveness of skilled aquatic therapy on functional improvements among chronic spinal cord injury patients with complex medical conditions.Education:Perpetual Help College of Med, Philippines, B.S. 1988 Physical Therapy

Perpetual Help College of Med, Philippines, M.D. 1997 Medicine

Harvard Medical School, Boston, MA, Residency 2003-2006, PM&R

University of Washington, Seattle, WA, Fellowship, 2006-2007 Spinal Cord InjuryThis author has the following disclosures:

124Indoor rock climbing after spinal cord injuryThursday, May 03, 2018 09:30 AM - 10:30 AMLearning Objectives:Share our early findings regarding the challenges and benefits of implementing an indoor rock climbing program for people with SCI.

Participants:Zakrasek E, Kiratli JPalo Alto Va , Palo Alto , CA, USAElissa Zakrasek, MDPalo Alto Va Bio:Dr. Zakrasek completed her PM&R training at Stanford University and has recently completed her Spinal Cord Injury Clinical Fellowship through Stanford/Palo Alto VA. She is passionate about SCI clinical medicine and research. She has wide-ranging clinical research interests in SCI medicine including adapted sports, urologic management, respiratory management and HO prophylaxis. She is committed to a career as a research-clinician in SCI medicine and will be starting a advanced research fellowship in SCI at the Palo Alto VA in January 2018. She herself is a very recent mother of two amazing children (two year old and 5 day old) and an athlete. Education:College: Brown University, RI (2002-2006) Medical School: UC Davis School of Medicine (2007-2012) Internship: Brigham and Women's Hospital (prelim internal medicine) (2012-2013) PM&R Residency: Stanford University (2013-2016) SCI Fellowship: Stanford University (2016-2017)This author has no relevant disclosures.Jenny Kiratli, PhDPalo Alto Va This author has no relevant disclosures.

125The Use of High Fidelity Human Simulation for Interdisciplinary Skill Training and Team Building for the Care of a Patient with Spinal Cord InjuryThursday, May 03, 2018 09:30 AM - 10:30 AM

Learning Objectives:1. The learner will identify components and outcomes of High Fidelity Human Simulation of a patient with SCI

Participants:Morina AThomas Jefferson University Hospital , Ocean City , NJ, USAAmanda Morina, PT,DPT,NCS,ATPThomas Jefferson University Hospital Bio:Amanda Morina received her BS in Interdisciplinary Health Services/Biology from St. Joseph’s University in 2004. She obtained her BS/MS in Physical Therapy from Thomas Jefferson University in 2006 and returned for her Doctorate in Physical Therapy in 2008. Since 2006, Amanda has worked in the acute hospital, inpatient rehabilitation unit, and outpatient areas within Thomas Jefferson University’s Department of Rehabilitation. Amanda became board certified as an American Physical Therapy Association (APTA) Neurologic Clinical Specialist in 2011 and serves as a lab instructor within the neurologic curriculum at Thomas Jefferson University. Amanda currently serves as a member of the Rehab Standards Committee for the American Spinal Injury Association (ASIA) and a participant in the Stroke and SCI Special Interest Groups of the APTA Neurologic Section. She obtained her Assistive Technology Professional (ATP) certification in 2016.Education:-St. Joseph’s University. Philadelphia, PA. Interdisciplinary Health Services/Minor in Biology 2004. -Thomas Jefferson University. Philadelphia, PA. BS/MS Physical Therapy 2006 -Thomas Jefferson University. Philadelphia, PA. Doctorate in Physical Therapy 2008. This author has no relevant disclosures.

126A systematic review on the epidemiology of war-related spinal cord injury among soldiers: Thursday, May 03, 2018 09:30 AM - 10:30 AMLearning Objectives:Discuss the characteristics of the spinal cord injury among soldiers, and how those features differ from the civilians with spinal cord injury.

Participants:Furlan J, Gulasingam S, Craven BLyndhurst Centre, Toronto Rehabilitation Institute & University of Toronto , Toronto , ON, CanadaJulio Furlan, MD, LLB, MBA, PhD, MSc, FRCPCLyndhurst Centre, Toronto Rehabilitation Institute & University of Toronto Bio:Julio C. Furlan, MD, LLB, MBA, PhD, MSc, FRCPC, is a staff neurologist and a Clinician Investigator in the Division of Physical Medicine and Rehabilitation and the SCI Rehabilitation

Program at the Lyndhurst Centre, Toronto Rehabilitation Institute, University Health Network, and an Assistant Professor in the Department of Medicine, Division of Physical Medicine and Rehabilitation, University of Toronto. He is a trained head and neck surgeon from Brazil, who holds a MBA degree in Health Administration, an MSc degree in Clinical Epidemiology, and a PhD degree in Neuroanatomy. In the past, Dr. Furlan has worked as an Associate Research Scientist in the Department of Genetics and Development, Toronto Western Research Institute, University Health Network from 2007 to 2012. Dr. Furlan has also been an Adjunct Scientist at Toronto Rehabilitation Institute, University Health Network from 2009-2016, inclusive. He recently completed five years of residency training in Adult Neurology at University of Toronto in June 2014. Most recently, he completed a two-year clinical fellowship in Neurorehabilitation and Neural Repair at Toronto Rehabilitation Institute and the University of Toronto in June 2016. Dr Furlan´s research has been focused on outcome measures (including clinical assessments, neuroimaging analysis, and neurophysiological assessments) and predictors of outcome (including sex and age) after traumatic and non-traumatic spinal cord injury. In addition he has interest and expertise in autonomic dysfunction after spinal cord injury and economic analyses. Dr. Furlan has received 43 awards over the past 15 years. He has had research funding support from Christopher and Dana Reeve Foundation, Wings for Life Research Foundation, Rick Hansen Foundation, and Cervical Spine Research Society.Education:University of São Paulo (São Paulo, Brazil), M.D. (1983-1988), Medicine University of São Paulo (São Paulo, Brazil), Residency (1989-1991), General Surgery University of São Paulo (São Paulo, Brazil), Residency (1991-1992), Preventive Medicine & Healthcare Systems University of São Paulo, (São Paulo, Brazil), Residency (1992-1994), Head and Neck Surgery Mackenzie University (São Paulo, Brazil), LL.B. (1994-1999), Law São Paulo Business School, Getúlio Vargas Foundation (São Paulo, Brazil), M.B.A. (1994-1999), Healthcare System and Hospital Administration University of São Paulo (São Paulo, Brazil), Ph.D. (1994-1999), Surgical Neuroanatomy University of Toronto (Toronto, Ontario, Canada), M.Sc. (2004-2006), Clinical Epidemiology Toronto Western Hospital, University Health Network (Toronto, Ontario, Canada), Research Fellowship (2003-2007), Spinal Cord Research University of Toronto (Toronto, Ontario, Canada), Residency (2009-2014), Neurology University of Toronto (Toronto, Ontario, Canada), Clinical Fellowship (2014-2016), Neurorehabilitation and Neural Repair This author has no relevant disclosures.Sivakumar Gulasingam, MBBS, FRCPCLyndhurst Centre, Toronto Rehabilitation Institute & University of Toronto Bio:Dr. Sivakumar Gulasingam is a staff Physiatrist attached to the Brain and Spinal Cord Program and Cardiovascular Prevention and Rehabilitation Program at the Toronto Rehabilitation Institute, University Health Network. He is Clinician Teacher and an Assistant Professor at the Department of Medicine, University of Toronto. He received his medical degree from the University of Colombo, Sri Lanka in 1998 and worked as a Spinal Cord and Rehabilitation Medicine Physician in Sri Lanka since 2001. Upon migrating to Canada, he completed his residency training in Physical Medicine & Rehabilitation (PMR) at the University of Toronto in 2006 and an additional one year clinical fellowship in Spinal Cord Injury (SCI)

Rehabilitation including Sexual Medicine and Cardiac Rehabilitation at the University of Toronto and the University of British Columbia. His areas of clinical practice include SCI rehabilitation, para sports, exercise medicine and men's health in SCI. Dr. Gulasingam is the current Objective Structured Clinical Examination (OSCE) Lead at the University of Toronto, Division of PMR, Chair of the International Rehabilitation Special Interest Group (SIG) and a member of the Education SIG of the Canadian Association of Physical Medicine and Rehabilitation (CAPMR). His research interests include para sports & para sports classification, men's health outcome measures & performance indicators in SCI and skin & wound care in SCI. He serves as an International Classifier with International Paralympic Committee for Para Athletics and Para Dance Sports. He is also the National Head of Classification for Para Dance Canada, National Trainer and Classifier for Athletics Canada and the Multisport Categorization Lead for the Invictus Games 2017.Education:2016 - 2017 Post Graduate Clinical Fellowship in Spinal Cord Injury Rehabilitation and Cardiac Rehabilitation Division of Physical Medicine & Rehabilitation, Department of Medicine, University of Toronto and Division of Physical Medicine & Rehabilitation, University of British Columbia, Canada 2011 - 2016 Post Graduate Training in Physical Medicine and Rehabilitation Division of Physical Medicine & Rehabilitation, Department of Medicine, University of Toronto, Ontario, Canada 2006 - 2007 Post Graduate Diploma in Applied Sociology - Medical major Faculty of Sociology, University of Colombo, Western Province, Sri Lanka 1992 - 1997 Bachelor of Medicine and Bachelor of Surgery (MBBS) Faculty of Medicine, University of Colombo, Western Province, Sri LankaThis author has no relevant disclosures.Beverly Craven, BA, MD, MSc, FRCPCLyndhurst Centre, Toronto Rehabilitation Institute & University of Toronto Bio:B. Catharine (Cathy) Craven, BA, MD, MSc, FRCPC is the Medical Lead of the Toronto Rehab Lyndhurst Centre Spinal Cord Rehabilitation Program and a Senior Scientist in the Neural Engineering and Therapeutics Team at Toronto Rehab’s Lyndhurst Centre within University Health Network. Dr. Craven is an Associate Professor in the Department of Medicine, Division of Physical Medicine and Rehabilitation, and Institutes of Rehabilitation Science and Health Policy Management and Evaluation at the University of Toronto, Canada. After completing a BA in Kinesiology at York University, Dr. Craven completed her Medical training and residency in Physical Medicine and Rehabilitation at McMaster University, and then completed training as a Clinical Scholar in Spinal Cord injury and a Master’s in Clinical Epidemiology at the University of Toronto. Dr. Craven has served as the Co- Chair of the 1st through 7th National SCI conference ( www.SCI2017.com ) in Canada, Scientific Officer for the Canadian Association of Physical Medicine and Rehabilitation, Chair of the Rick Hansen Institute CARE Committee, Inaugural Chair of the newly founded Canadian Spinal Cord Injury – Rehabilitation Association. Dr. Craven holds research funding from the Craig H. Nielsen Foundation, Canadian Institute of Health Research, Rick Hansen Institute, Ontario Neurotrauma Foundation and Physician Services Inc. Dr Craven was the 2017 CAPMR Award of Merit Recipient. Dr Craven’s current

research focuses on reducing Endocrine Metabolic disease (fracture, heart disease, and diabetes) risk after spinal cord injury and enhancing health services for patients with SCI in Canada by 2020 through leadership of the E-Scan Atlas (www.idapt.com/research/E-scan )and SCI-HIGH projects (https://sites.google.com/view/sci-high/home). Dr Craven has published over 125 papers on related topics. Education:York University (Ontario, Canada), BA (1989), Physical Education McMaster University (Ontario, Canada), MD (1994), Medicine McMaster University (Ontario, Canada), FRCPC (1998), Physiatry University of Toronto (Ontario, Canada), MSc (2007), Clinical Epidemiology This author has no relevant disclosures.

127A systematic review on the Health Economics of the spinal cord injury or disease among veterans of war Thursday, May 03, 2018 09:30 AM - 10:30 AMLearning Objectives:Discuss the main features of health economics of the spinal cord injury or disease among veterans of war, and how those costs differ from the civilians with spinal cord injury or disease.

Participants:Furlan J, Gulasingam S, Craven BLyndhurst Centre, Toronto Rehabilitation Institute & University of Toronto , Toronto , ON, CanadaJulio Furlan, MD, LLB, MBA, PhD, MSc, FRCPCLyndhurst Centre, Toronto Rehabilitation Institute & University of Toronto Bio:Julio C. Furlan, MD, LLB, MBA, PhD, MSc, FRCPC, is a staff neurologist and a Clinician Investigator in the Division of Physical Medicine and Rehabilitation and the SCI Rehabilitation Program at the Lyndhurst Centre, Toronto Rehabilitation Institute, University Health Network, and an Assistant Professor in the Department of Medicine, Division of Physical Medicine and Rehabilitation, University of Toronto. He is a trained head and neck surgeon from Brazil, who holds a MBA degree in Health Administration, an MSc degree in Clinical Epidemiology, and a PhD degree in Neuroanatomy. In the past, Dr. Furlan has worked as an Associate Research Scientist in the Department of Genetics and Development, Toronto Western Research Institute, University Health Network from 2007 to 2012. Dr. Furlan has also been an Adjunct Scientist at Toronto Rehabilitation Institute, University Health Network from 2009-2016, inclusive. He recently completed five years of residency training in Adult Neurology at University of Toronto in June 2014. Most recently, he completed a two-year clinical fellowship in Neurorehabilitation and Neural Repair at Toronto Rehabilitation Institute and the University of Toronto in June 2016. Dr Furlan´s research has been focused on outcome measures (including clinical assessments, neuroimaging analysis, and neurophysiological assessments) and predictors of outcome (including sex and age) after traumatic and non-traumatic spinal cord injury. In addition he has interest and expertise in autonomic dysfunction after spinal cord injury and economic

analyses. Dr. Furlan has received 43 awards over the past 15 years. He has had research funding support from Christopher and Dana Reeve Foundation, Wings for Life Research Foundation, Rick Hansen Foundation, and Cervical Spine Research Society.Education:University of São Paulo (São Paulo, Brazil), M.D. (1983-1988), Medicine University of São Paulo (São Paulo, Brazil), Residency (1989-1991), General Surgery University of São Paulo (São Paulo, Brazil), Residency (1991-1992), Preventive Medicine & Healthcare Systems University of São Paulo, (São Paulo, Brazil), Residency (1992-1994), Head and Neck Surgery Mackenzie University (São Paulo, Brazil), LL.B. (1994-1999), Law São Paulo Business School, Getúlio Vargas Foundation (São Paulo, Brazil), M.B.A. (1994-1999), Healthcare System and Hospital Administration University of São Paulo (São Paulo, Brazil), Ph.D. (1994-1999), Surgical Neuroanatomy University of Toronto (Toronto, Ontario, Canada), M.Sc. (2004-2006), Clinical Epidemiology Toronto Western Hospital, University Health Network (Toronto, Ontario, Canada), Research Fellowship (2003-2007), Spinal Cord Research University of Toronto (Toronto, Ontario, Canada), Residency (2009-2014), Neurology University of Toronto (Toronto, Ontario, Canada), Clinical Fellowship (2014-2016), Neurorehabilitation and Neural Repair This author has no relevant disclosures.Sivakumar Gulasingam, MBBS, FRCPCLyndhurst Centre, Toronto Rehabilitation Institute & University of Toronto Bio:Dr. Sivakumar Gulasingam is a staff Physiatrist attached to the Brain and Spinal Cord Program and Cardiovascular Prevention and Rehabilitation Program at the Toronto Rehabilitation Institute, University Health Network. He is Clinician Teacher and an Assistant Professor at the Department of Medicine, University of Toronto. He received his medical degree from the University of Colombo, Sri Lanka in 1998 and worked as a Spinal Cord and Rehabilitation Medicine Physician in Sri Lanka since 2001. Upon migrating to Canada, he completed his residency training in Physical Medicine & Rehabilitation (PMR) at the University of Toronto in 2006 and an additional one year clinical fellowship in Spinal Cord Injury (SCI) Rehabilitation including Sexual Medicine and Cardiac Rehabilitation at the University of Toronto and the University of British Columbia. His areas of clinical practice include SCI rehabilitation, para sports, exercise medicine and men's health in SCI. Dr. Gulasingam is the current Objective Structured Clinical Examination (OSCE) Lead at the University of Toronto, Division of PMR, Chair of the International Rehabilitation Special Interest Group (SIG) and a member of the Education SIG of the Canadian Association of Physical Medicine and Rehabilitation (CAPMR). His research interests include para sports & para sports classification, men's health outcome measures & performance indicators in SCI and skin & wound care in SCI. He serves as an International Classifier with International Paralympic Committee for Para Athletics and Para Dance Sports. He is also the National Head of Classification for Para Dance Canada, National Trainer and Classifier for Athletics Canada and the Multisport Categorization Lead for the Invictus Games 2017.Education:2016 - 2017 Post Graduate Clinical Fellowship in Spinal Cord Injury Rehabilitation and Cardiac

Rehabilitation Division of Physical Medicine & Rehabilitation, Department of Medicine, University of Toronto and Division of Physical Medicine & Rehabilitation, University of British Columbia, Canada 2011 - 2016 Post Graduate Training in Physical Medicine and Rehabilitation Division of Physical Medicine & Rehabilitation, Department of Medicine, University of Toronto, Ontario, Canada 2006 - 2007 Post Graduate Diploma in Applied Sociology - Medical major Faculty of Sociology, University of Colombo, Western Province, Sri Lanka 1992 - 1997 Bachelor of Medicine and Bachelor of Surgery (MBBS) Faculty of Medicine, University of Colombo, Western Province, Sri LankaThis author has no relevant disclosures.Beverly Craven, BA, MD, MSc, FRCPCLyndhurst Centre, Toronto Rehabilitation Institute & University of Toronto Bio:B. Catharine (Cathy) Craven, BA, MD, MSc, FRCPC is the Medical Lead of the Toronto Rehab Lyndhurst Centre Spinal Cord Rehabilitation Program and a Senior Scientist in the Neural Engineering and Therapeutics Team at Toronto Rehab’s Lyndhurst Centre within University Health Network. Dr. Craven is an Associate Professor in the Department of Medicine, Division of Physical Medicine and Rehabilitation, and Institutes of Rehabilitation Science and Health Policy Management and Evaluation at the University of Toronto, Canada. After completing a BA in Kinesiology at York University, Dr. Craven completed her Medical training and residency in Physical Medicine and Rehabilitation at McMaster University, and then completed training as a Clinical Scholar in Spinal Cord injury and a Master’s in Clinical Epidemiology at the University of Toronto. Dr. Craven has served as the Co- Chair of the 1st through 7th National SCI conference ( www.SCI2017.com ) in Canada, Scientific Officer for the Canadian Association of Physical Medicine and Rehabilitation, Chair of the Rick Hansen Institute CARE Committee, Inaugural Chair of the newly founded Canadian Spinal Cord Injury – Rehabilitation Association. Dr. Craven holds research funding from the Craig H. Nielsen Foundation, Canadian Institute of Health Research, Rick Hansen Institute, Ontario Neurotrauma Foundation and Physician Services Inc. Dr Craven was the 2017 CAPMR Award of Merit Recipient. Dr Craven’s current research focuses on reducing Endocrine Metabolic disease (fracture, heart disease, and diabetes) risk after spinal cord injury and enhancing health services for patients with SCI in Canada by 2020 through leadership of the E-Scan Atlas (www.idapt.com/research/E-scan )and SCI-HIGH projects (https://sites.google.com/view/sci-high/home). Dr Craven has published over 125 papers on related topics. Education:York University (Ontario, Canada), BA (1989), Physical Education McMaster University (Ontario, Canada), MD (1994), Medicine McMaster University (Ontario, Canada), FRCPC (1998), Physiatry University of Toronto (Ontario, Canada), MSc (2007), Clinical Epidemiology This author has no relevant disclosures.

128

Glenohumeral Joint Biomechanics, Pain and Stroke Pattern Variability During Pediatric Manual Wheelchair Mobilty: A Longitudinal EvaluationThursday, May 03, 2018 09:30 AM - 10:30 AMLearning Objectives:Discuss how pediatric manual wheelchair mobility can be quantified and how it changes over time.

Participants:1Slavens B, 2Schlidt K, 1Schnorenberg A, 3Vogel L, 4Harris G1University of Wisconsin-Milwaukee , Milwaukee , WI, USA; 2Medical College of Wisconsin , Milwaukee , WI, USA; 3Shriners Hospitals for Children , Chicago , WI, USA; 4Marquette University , Milwaukee , WI, USABrooke Slavens, PhD, MSUniversity of Wisconsin-Milwaukee Bio:Brooke Slavens is an Associate Professor in the Department of Occupational Science & Technology and Biomedical Engineering at the University of Wisconsin-Milwaukee. She is the Director of the Movement Analysis for Biomedical Innovation & Technology (Mobility) Lab. Dr. Slavens received her B.S. degree in Biomedical Engineering from the University of Iowa and her M.S. and Ph.D. degrees in Biomedical Engineering from Marquette University. Dr. Slavens completed a Postdoctoral Fellowship in Pediatric Mobility through the Orthopaedic and Rehabilitation Engineering Center (OREC) at Marquette University and the Medical College of Wisconsin.

Dr. Slavens’ research interests include pediatric mobility, upper extremity motion analysis, wheelchair biomechanics, rehabilitation engineering, and orthopaedic biomechanics. She has received extramural funding from NIH, NSF, and NIDRR/NIDILRR for her research. She is an active member of the American Society of Biomechanics (ASB), IEEE Engineering in Medicine and Biology Society (EMBS), Gait and Clinical Movement Analysis Society (GCMAS) and the Rehabilitation Engineering and Assistive Technology Society of North America (RESNA). Education:University of Iowa, Iowa City, IA B.S. 12/2001 Biomedical Engineering Marquette University, Milwaukee, WI M.S. 8/2004 Biomedical Engineering Marquette University, Milwaukee, WI Ph.D. 12/2007 Biomedical Engineering Marquette University, Milwaukee, WI Postdoctoral 8/2010 Biomedical Engineering Northwestern University, Chicago, IL NIH K12 5/2015 Rehabilitation Engineering This author has no relevant disclosures.Kevin Schlidt, B.S.Medical College of Wisconsin This author has no relevant disclosures.Alyssa Schnorenberg, MSUniversity of Wisconsin-Milwaukee This author has no relevant disclosures.

Lawrence Vogel, MDShriners Hospitals for Children This author has no relevant disclosures.Gerald Harris, PhD, PEMarquette University This author has no relevant disclosures.

129PREVALENCE OF PRE-HOSPITAL HAEMODYNAMIC INSTABILITY IN THE ACUTE PHASE OF TRAUMATIC SPINAL CORD INJURY (SCI)Thursday, May 03, 2018 09:30 AM - 10:30 AMLearning Objectives:Acute care; trauma management

Participants:1Clark J, 2Rao P, 1Freeman B, 1Atherton M1Royal Adelaide Hospital , Adelaide , South aust, Australia; 2Royal Adelaide Hospial , Adelaide , South aust, AustraliaJILLIAN Clark, Ph.D.Royal Adelaide Hospital Bio:Dr Jillian Clark is a Senior Research Fellow, Spinal Services, Royal Adelaide Hospital and Affiliate Professor, School of Medicine, Faculty of Health and Medical Sciences, University of Adelaide, Adelaide, South Australia Education:Ph.D ( Medicine)This author has no relevant disclosures.Prashanthe Rao, MD; Ph.D.Royal Adelaide Hospial This author has no relevant disclosures.Brian Freeman, MD, Ph.D.Royal Adelaide Hospital This author has no relevant disclosures.Mike Atherton, MDRoyal Adelaide Hospital This author has no relevant disclosures.

130Best Practice for Heterotopic Ossification Prevention and ManagementThursday, May 03, 2018 12:45 PM - 02:15 PMLearning Objectives:

On completion of this symposium participants will be able to: • Explain Heterotopic Ossification (HO) in terms of its presentation and potential morbidity in those with spinal cord injury (SCI). • Describe the impact of HO on ROM and mobility, and address the unique challenges it creates in SCI therapy management including wheelchair seating. • Discuss screening, prophylaxis, and medical treatment options for HO, including medication type, dosage, and duration.

Participants:1Crew J, 2Hastings J1Santa Clara Valley Medical Center , San Jose , California, United states; 2University of Puget Sound , Tacoma , Washington, United statesJames Crew, MDSanta Clara Valley Medical Center Bio:Dr. James Crew has been faculty at Santa Clara Valley Medical Center (SCVMC) for eight years, following his training in PM&R and Spinal Cord Injury (SCI) Medicine at the University of Washington. In 2011, he was appointed the Chief of Spinal Cord Injury at SCVMC. This position includes program oversight of an Inpatient SCI Unit, and collaboration with the Rehab Trauma Center at SCVMC for early SCI management pre-rehabilitation including ventilator management. Dr. Crew is also closely involved with the outpatient clinics at SCVMC to ensure smooth clinical transition and management of patients with SCI across the continuum of care. Additionally, Dr. Crew was appointed Chair of PM&R at SCVMC in 2014, overseeing clinical operations for a moderately large sized inpatient and outpatient academic neurorehabilitation practice with CARF Accreditation in seven programs. While his clinical work has been focused on treating individuals with SCI in the acute care and inpatient rehabilitation settings, he is also boarded in Neuromuscular Medicine and is actively involved in electrodiagnostics in the inpatient and outpatient setting. His research experience has focused on optimizing function and quality of life after SCI. He has participated as a co-investigator in the Geron OPC1 Stem Cell trial in SCI. He has clinical research experience with biomechanical devices including as the co-PI of a safety and efficacy evaluation of the Ekso wearable exoskeletal device for those with SCI. He currently serves as the SCVMC site Co-PI for the Asterias Stem Cell Clinical Trial in SCI, and was the SCVMC site Co-PI for the Geron Stem Cell Clinical Trial in SCI. Further, he was the SCVMC site PI for the Asubio SUN13837 clinical trial in acute cervical SCI. In addition, he previously received funding through the American Spinal Injury Association Young Investigator Award for his project on the Treatment of Vitamin D Deficiency in Persons with SCI. Dr. Crew is also actively involved in residency training, currently Chair of the Stanford PM&R Research and Quality Committee and having served as site director at SCVMC for the Stanford University PM&R program. He is a member of the Graduate Medical Education Committee at SCVMC, and was recently appointed onto the CNS Council in AAPMR in 2017 as Vice Chair of Education. Dr. Crew is also interested in SCI patient advocacy, having joined the ASIA Health Advocacy Commitee in 2017. Education:Creighton University (Omaha, NE) 1996-2000, Bachelor of Arts, Philosophy, Summa Cum Laude

Creighton University Medical School (Omaha, NE) 2000-2004, Doctorate of Medicine

University of Washington (Seattle, WA) 2004-2005, Transitional Year Internship

University of Washington (Seattle, WA) 2005-2008, Physical Medicine and Rehabilitation Residency

University of Washington/VA Puget Sound Healthcare (Seattle, WA) 2008-2009, Spinal Cord Injury Medicine FellowshipThis author has no relevant disclosures.Jennifer Hastings, PT, PhDUniversity of Puget Sound Bio:Dr. Hastings is a board certified clinical specialist in neurologic physical therapy and with over 30 years as a practicing clinician. She worked for 20 years as a SCI inpatient rehabilitation specialist at the Seattle VA. Currently she has a part time practice in wheelchair and seating prescription and functional skills training for SCI. Dr. Hastings is a professor at the University of Puget Sound School of Physical Therapy where she teaches portions of adult neurologic rehabilitation curriculum and advanced neurologic physical therapy electives. Dr. Hastings actively researches physical therapy interventions for neurologic clients and has published in Archives of Physical Medicine and Rehabilitation, Physical Therapy, and the American Journal of Physical Medicine and Rehabilitation.Education:Doctor of Philosophy University of Washington, School of Nursing Seattle, WA Nursing Science June 2006 Dissertation: Effectiveness of Postural Intervention via Manual Wheelchair Change; Feasibility of Teleconsultation Delivery

Master of Science Boston University, Sargent College Boston, MA Physical Therapy May 1985 Thesis: The long term use of lower extremity bracing following spinal cord injury rehabilitation

Bachelor of Arts University of California Berkeley, CA Physiology August 1981 This author has no relevant disclosures.

131Measuring Bowel Dysfunction After SCI: Strategies and FindingsThursday, May 03, 2018 12:45 PM - 02:15 PMLearning Objectives:1. Discuss different ways of assessing neurogenic bowel dysfunction and complications using the SCI International Datasets for Bowel Function. 2. Discuss the use of patient reported measures as identified in the Common Data Elements to assess bowel dysfunction after SCI. 3. Discuss research findings from quantitative and qualitative studies on bowel dysfunction after SCI.

Participants:1Tate D, 2Post M, 3Tulsky D, 1Rodriguez G1University of Michigan , Ann Arbor , Michigan, USA; 2University of Groningen Department of Rehabilitation Medicine , Groningen , NA, The netherlands; 3University of Delaware College of Health Sciences , Maryland , Delaware, USADenise Tate, PhDUniversity of Michigan Bio:Dr. Tate is a Professor and Associate Chair for Research in the Department of Physical Medicine and Rehabilitation at the University of Michigan Medical School. For the past 30 years, she served as the PI for the University of Michigan SCI Model System (U-M SCIMS), funded by NIDILRR. Her current funding includes the SCIRP- Congressionally Directed Medical Research Program from the U.S. the Department of Defense; Craig Neilsen Foundation (CHN) for a multi-site international research project examining the validation of a measure of quality of life (QOL) to be used in SCI clinical trials; and the National Institute on Disability Independent Living and Rehabilitation Research (NIDILRR). Most recently her SCI research has focused on neurogenic bowel and bladder dysfunction after SCI and their impact on quality of life, the role of socio environmental factors, and adaptation to complications, aging and decision making related to bowel and bladder management. She has experienced in clinical trials, observational and qualitative studies. Throughout the years she has served as a panel reviewer and/or chair for the NIH, AHRQ, PCORI, CHN, CDC and CDMRP. She was a member of the NINDS/NIH Common Data Elements QOL taskforce, and served on several advisory boards (i.e. National Center for Medical Rehabilitation Research at the NIH, the American Congress of Rehabilitation Medicine, American Spinal Injury Association and the National Injury Center of CDC). Education:Gama Filho University (Rio de Janeiro, Brazil), BS 1968-73 Psychology Fundacao Getulio Vargas (Rio de Janeiro, Brazil) MS, 1973-74 Experimental Psychology Michigan State University (Lansing, Michigan) PhD , 1974-1979 Michigan State University Clinical Rehabilitation Post Doctoral Program (1980-81)This author has no relevant disclosures.Marcel Post, PhDUniversity of Groningen Department of Rehabilitation Medicine

Bio:Dr. Post has worked as associate professor at the Department of Rehabilitation medicine, Nursing Sciences and Sports of the University Medical Center Utrecht and as senior researcher and leader of the spinal cord injury research program at De Hoogstraat Rehabilitation since 2005. In 2014 he was been appointed research (“special”) professor of spinal cord injury rehabilitation at the University of Groningen. His main research interests include rehabilitation care including bowel care, participation, quality of life, psychological factors, self-management, and family empowerment in persons with spinal cord injury, and instrument development in these areas. For many years he have been involved in the development, translation and/or validation of tests and questionnaires. He has served on the executive committee of the International SCI Data Sets project since its origin in 2002 and have co-chaired the development of the Quality of Life Data Set and the Activities and Participation Data Set. He has extensive experience as PI of different types of studies, including psychometrical studies, multicenter cohort studies and a multicentre randomized clinical trial. With his research team he published a landmark article on the Archives of Physical Medicine and Rehabilitation on outcomes of neurogenic bowel management (2015). Findings from this large study will be discussed at this course. Dr. Post is also a methodologist with expertise in measurement outcomes. Education:Utrecht University, The Netherlands, MA in Psychology (1983-85) Utrecht University, the Netherlands, PhD in Psychology (1992-97). This author has no relevant disclosures.David Tulsky, PhDUniversity of Delaware College of Health Sciences Bio:Dr. Tulsky is Professor in the Department of Physical Therapy and Director of the Center for Health Assessment Research and Translation at the University of Delaware. He received his PhD from UIC with specializations in Clinical Psychology and Psychometrics. He completed post-doctoral fellowship at Rush-Presbyterian St. Luke’s Medical Center in Chicago where he developed measures of quality of life for cancer patients. Dr. Tulsky has served as PI and Co-I on several measurement related grants from the NIH, NIDRR, DoD, VA including serving as a PI on the SCI Model Systems from NIDRR, PI of NIH multi-site R-01 study to optimize PROMIS for individuals with SCI and a U-01 PROMIS research grant to validate PROMIS in children with SCI and TBI, NIDRR grants to optimize PROMIS for individuals with TBI, and was Project PI on a large multisite study to validate NIH Toolbox in individuals with SCI, TBI, and Stroke. Dr. Tulsky is serving as the PI of a Craig H Neilsen Foundation grant to develop a symptom-monitoring/self-management system using SCI-QOL item banks and motion-graphic animated video for symptoms of pain, depression, and anxiety for individuals with SCI. The SCI-QOL project contains data on bowel management and complications from a group of SCIMS centers. This data will be discussed during his presentation. Over 15 years, Dr. Tulsky has worked on the development of NIH Common Data Elements measures and has validated and optimized them for rehabilitation populations. As Co-Principal Investigator, Dr. Tulsky has expertise in implementing outcomes measures for individuals with SCI and will provide access to qualitative data collected during previous projects. Dr. Tulsky has successfully led several multisite collaborative studies of individuals with SCI and has a history of successful collaboration with other project investigators.

Education:University of Illinois, Urbana, Chicago BA in Psychology (1977-82) University of Illinois at Chicago MA in Clinical Psychology (1984-86) University of Illinois at Chicago PhD Clinical Psychology, Psychometrics, Research Methods (1984-89) Rush Presbyterian St. Luke Cancer Center Postdoctoral in Health Psychology (1989) This author has no relevant disclosures.Gianna Rodriguez, MDUniversity of Michigan Bio:Dr. Rodriguez is an Associate Professor in the Department of Physical Medicine and Rehabilitation at the University of Michigan. She serves as the Medical Director for the Wheelchair Seating and Spinal Cord Injury programs serving both inpatients and outpatients in SCI. She is in the editorial board of the Journal of Head Trauma Rehabilitation and Topics in Spinal Cord Injury Rehabilitation. Her research interests include bladder and bowel functions after SCI and she is a member of the Michigan Bowel Program implemented in conjunction with the Division of Gastroenterology at the University of Michigan Health Systems. She is a member of the International Standards Committee of ASIA and served as a Co Investigator for the UM-SCIMS. Dr. Rodriguez was recently awarded a clinical trials grant from the Craig Neilsen Foundation to study the smart pill I mapping the gut of persons with SCI. She will discuss this study during her presentation. Education:Ateneo de Manila University, Manila, Philippines BS in Biology (1985-1990) University of the East - RM Medical Center, Manila Philippines, MD degree in Medicine (1990-94)This author has no relevant disclosures.

132Stimulating Spinal Cord Injury: Moving Neuromodulation of Gait Past Proof of PrincipleThursday, May 03, 2018 12:45 PM - 02:15 PMLearning Objectives:1) Discuss the rationale and underlying principles of neuromodulation in SCI

2) Appreciate the different approaches being investigated in spinal cord and peripheral nerve stimulation to augment stepping after SCI

3) Understand the challenges in this emerging field of neural augmentation for SCI

Participants:1Tansey K, 2Lee K, 3Krenn M1Methodist Rehab/Ummc/Jackson Vamc , Jackson , MS, USA; 2Mayo Clinic , Rochester , MN, USA; 3Univ Miss Med Ctr , Jackson , MS, USAKeith Tansey, MD, PhDMethodist Rehab/Ummc/Jackson Vamc

Bio:Keith E. Tansey, MD, PhD, is a Senior Scientist in the Center for Neuroscience and Neurological Recovery and the NeuroRobotics Lab at Methodist Rehabilitation Center, a Professor in the Departments of Neurosurgery (Division of Physical Medicine and Rehabilitation) and Neurobiology and Anatomical Sciences and in the Neurotrauma Center of the Neuro Institute at the University of Mississippi Medical Center, and a Physician Scientist on the Spinal Cord Injury Medicine and Research Services at the G.V. (Sonny) Montgomery Veterans Administration Medical Center in Jackson Mississippi, USA. After receiving his bachelor’s and master’s degrees in biology (biomechanics) from Stanford University, Tansey earned his medical and doctoral degrees (neuroscience) at the University of Texas Southwestern Medical Center. He completed his residency in neurology at Washington University and fellowships in neurorehabilitation and spinal cord injury research there and at the University of California at Los Angeles. He was board-certified in Neurology and then earned subspecialty certifications in Spinal Cord Injury Medicine and Neural Repair and Rehabilitation. Dr. Tansey has served on the boards of the American Society for Neurorehabilitation and the International Society for Restorative Neurology (Past-President), and is the current President of the American Spinal Injury Association. He also works on several committees, advisory boards, and planning groups for other national and international organizations. Tansey is an award-winning medical educator and with colleagues from Heidelberg, has recently co-edited a textbook, “Neurological Aspects of Spinal Cord Injury” for Springer. He has been invited to speak on his research internationally and won awards for his group’s work from the American Spinal Injury Association and the American Association of Neuromuscular and Electrodiagnostic Medicine. He has had funding support for his research from the NIH, NIDDR/NIDILLR, DoD, VA, Neilsen Foundation, Fox Foundation, and Mobility Foundation Center. He studies plasticity in neural circuits for pain, autonomic function, locomotion, and upper extremity function in animal models and humans after spinal cord injury, with an interest in shaping that plasticity to improve functional recovery.Education:Stanford University, BS, MS, 1985 University of Texas Southwestern Medical Center, MD, PhD, 1994This author has the following disclosures:

ConsultantNeuralstem Trial (medical monitor) Unite 2 Fight Paralysis (scientific advisor) WISE trial (data safety and monitoring board)Kendall Lee, MD, PhDMayo Clinic Bio:Professor and Consultant of Neurosurgery, Physiology and Biomedical Engineering, and Physical Medicine and Rehabilitation A. Personal Statement I have extensive research expertise in neuroscience, specifically in electrophysiology, stereotactic and functional neurosurgery, and electrochemistry. I received my M.D. and Ph.D. degrees through the Medical Scientist Training Program at Yale University in 1998. My doctoral dissertation was on neurochemical modulation of synchronized oscillations in the thalamus (Department of Neurobiology). I was a neurology resident at Harvard Medical School and

completed my neurosurgery residency at Dartmouth-Hitchcock Medical Center, with an emphasis on stereotactic and functional neurosurgery and deep brain stimulation (DBS). During my residency I also completed a postdoctoral research fellowship in electrophysiology. In 2006, I joined Mayo Clinic as a stereotactic and functional neurosurgeon with clinical emphasis on DBS and now am 50% clinical and 50% research. I founded and am co-director of the Mayo Neural Engineering Laboratories (NEL) for nine years, during which time the laboratory has grown from 5 to 42 full and part-time personnel. Under my leadership, the laboratory has mentored 14 graduate school and medical school students. In 2015 I became the chair of Enterprise Neurosurgery Research across Mayo’s three sites, and I am sitting member of BNVT study sections for NIH. For the past eleven years, my research has focused on elucidating the therapeutic mechanisms of electrical stimulation in restoring function in both brain (DBS) and spinal cord. The lab’s endeavors have included intensive collaboration with Mayo’s Division of Engineering to develop novel research devices such as wireless human-compatible fast-scan cyclic voltammetry designed for use during human and animal DBS surgery to monitor the neurochemical and electrophysiological bases of DBS, as well as research tools and novel imaging strategies to trace circuitry effects of DBS as a function of stimulation parameters and DBS target. Lastly, our lab is working to improve intraspinal microstimulation (ISMS), which is believed to be capable of producing longer-lasting muscle contractions, at least in part, by the lower stimulation amplitudes associated with direct stimulation of spinal circuits.Education:University of Colorado at Denver, B.A., 1987-1990 Yale University Graduate School, M.Phil., 1991-1994 Yale University School of Medicine, M.D., 1991-1998 Yale University Graduate School, Ph.D., 1994-1998 This author has no relevant disclosures.Matthias Krenn, PhDUniv Miss Med Ctr Bio:Instructor A. Personal Statement I have the expertise, training, expertise, and motivation necessary to carry out the proposed research project successfully. I have a broad background in electrical stimulation of muscle and nervous tissues, with specific training and expertise in transcutaneous spinal cord stimulation. In the early phase of my career, I was strongly involved in electrical stimulation systems for restoration of lower extremity function in paraplegic individuals, with focus on stimulation parameter optimization and neuromuscular assessment using ultrasound imaging, electro- and acceleromyograph. Subsequently, I worked with paraplegic patients with lower motor neuron lesion in a clinical environment. In the project, I contributed to clinical and scientific examinations of subjects from various international rehabilitations centers. In the frame of two projects, funded by the Vienna Science and Technology Fund (WWTF LS11-057) and Wings for Life Spinal Cord Research Foundation (WfL-AT-007/11), which were dedicated to modification of spasticity and non-invasive restoration of movement functions in spinal cord injured via neuromodulation, I was responsible for development and application of stimulation and recording technologies and covered the clinical engineering part in all assessment and intervention procedures. The work on both projects was in close collaboration with physiotherapist and physicians. In this involvement, I could gain profound experience in

both non-invasive and epidural electrical stimulation for inducing neuromodulation inputs in the posterior roots of the lumbosacral spinal cord. The clinical assessments and interventions were applied in resting and walking conditions, on spinal cord injured as well as in control subjects with the intact central nervous system. The transcutaneous spinal cord stimulation is a novel approach for clinical neuromodulation, which requirements specific technological developments and improvements. To refine selectivity of stimulation, I developed a compact computer-controlled stimulation system, which can enable single or multiple segments of an electrode array. The new electrode prototypes could focus on selective or predominant uni- and bilateral segmental stimulation of the lumbosacral posterior-roots. In combination with additional stimulation of peripheral afferent nerve branches extended paradigms for modification of electrically elicited spinal reflexes could be introduced, which refine the assessment of residual functionality of the injured spinal cord, but also support analysis of spinal mechanisms in the intact spinal cord. My current research interest is strongly dedicated to applications of electrical stimulation to generate sustained afferent inputs to the spinal networks for improving neuromuscular functions in the lower extremities of spinal cord injured humans. For neuromodulation approaches, a new assessment methodology of the sensory-motor integration will be essential for successful applications in spinal cord injured individuals. Education:Vienna University of Technology, Austria, MSc, 04/2007 Medical University of Vienna, Austria, PhD, 09/2015 This author has no relevant disclosures.

133STEEL Acute Pediatric Myelitis: Diagnosis, differentiation and managementThursday, May 03, 2018 12:45 PM - 02:15 AMLearning Objectives:1) Discuss the presentations of acute flaccid myelitis and transverse myelitis in a child. 2) Anticipate and differentiate functional outcomes for children with different types of myelitis. 3) Provide recommendations for medical, urologic and rehabilitation strategies for a child with myelitis.

Participants:Tillema J, Granberg C, Driscoll S, Landry BMayo Clinic Children's Center , Rochester , MN, USAJan-Mendelt Tillema, MDMayo Clinic Children's Center Bio:Dr Tillema completed a research fellowship, Pediatrics residency and Child Neurology Fellowship at Cincinnati Children's followed by a Multiple Sclerosis Fellowship at the Mayo Clinic. His practice at Mayo Clinic Children's Center includes the care of children and adolescents with neurological problems with special clinical interest in pediatric and early adulthood presentation of Multiple Sclerosis and other demyelinating diseases, neuro-immunology, leukoencephalopathies and neuro-imaging features of these diseases. He has

several research grants and is currently focused on MRI and other neuroimaging biomarkers in demyelinating disease both for the diagnostic process and prognosis of future symptoms and disability.Education:Katholieke Universiteit Nijmegen (Radboud University Nijmegen), Nijmegen, Netherlands - MD 07/1997 - 08/2005 Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio - Research Fellowship 10/2005 - 06/2006 Pediatric Residency, Cinncinnati Children's Hospital Medical Center, Cincinnati, Ohio - Resident, Pediatric Residency 07/2006 - 06/2008 Child Neurology Fellowship, Cincinnati Children's Hospital Medical Center and the University of Cincinnati College of Medicine, Cincinnati, Ohio - Resident, Child Neurology Residency Residency Director: Donald L. Gilbert, M.D., M.S. 07/2008 - 06/2011 Multiple Sclerosis Fellowship, Mayo Clinic, Rochester, Minnesota - Fellow, Multiple Sclerosis Fellowship Fellowship director: Claudia Lucchinetti, M.D. 07/2011 - 06/2012 This author has no relevant disclosures.Candace Granberg, MDMayo Clinic Children's Center Bio:Dr. Granberg completed Medical School and her Urology residency at Mayo Clinic in Rochester MN and followed this with Pediatric Urology Fellowship at Children's Medical Center-Fellowship, University of Texas Southwestern Medical Center at Dallas. She returned to care for children at Mayo Clinic Children's Center where she's been active in various leadership roles within her department and the institution. Her practice is dedicated to the care of children and adolescents with surgical urologic disorders. She's active as a national speaker and researcher. Education:Jamestown College, Jamestown, North Dakota - BA, Chemistry 1996 - 2000 University of North Dakota School of Medicine and Health Sciences, Fargo, North Dakota - MD 2001 - 2005 Mayo School of Graduate Medical Education, Mayo Clinic College of Medicine, Rochester, Minnesota - Internship 2005 - 2006 Mayo School of Graduate Medical Education, Mayo Clinic College of Medicine, Rochester, Minnesota - Resident, Urology 2005 - 2010 Children's Medical Center-Fellowship, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas - Fellow, Pediatric Urology 2011 - 2012 This author has no relevant disclosures.Sherilyn Driscoll, MDMayo Clinic Children's Center Bio:Dr. Driscoll is a pediatric rehabilitation physician at Mayo Clinic Children's Center following completion of her PM&R residency at Mayo Clinic and subsequent pediatric subspecialization. She serves as the Program Director for the Pediatric Rehabilitation Medicine Fellowship, Division Chair for Pediatric Rehabilitation and Vice Chair of Visibility for the Children's Center as well as a Board Director for the American Board of PM&R. She cares for children and

adolescents with all types of rehabilitation needs and has special interest in spina bifida and brain injury. Education:Pomona College - BA, Biology 1981 - 1985 University of New Mexico - MD 1985 - 1990 University of New Mexico - Internship, Internal Medicine 1990 - 1991 Mayo School of Graduate Medical Education, Mayo Clinic College of Medicine - Resident, Physical Medicine and Rehabilitation 1991 - 1994

Additional Education Active Leaders Program intensive group leadership training program Chaska, Minnesota 2008 Career and Leadership Program Individual leadership development program Mayo Clinic 2008 - 2009

This author has no relevant disclosures.Brad Landry, DO, MSPTMayo Clinic Children's Center Bio:Dr Landry started his career as a physical therapist but then changed direction towards medicine. He completed his PM&R residency and his Pediatric Rehabilitation Fellowship at Mayo Clinic in Rochester, MN where he's been on staff since. He serves as the Medical Director for the pediatric inpatient rehabilitation unit. He sees children and adolescents with a wide variety of rehabilitation needs but has special interest in chronic pain, hypermobility syndrome and musculoskeletal disorders. His research is focused on chronic pain in children and adolescents. Education:University of Hartford, West Hartford, Connecticut - BS, Health Sciences 08/1998 - 12/2001 University of Hartford, West Hartford, Connecticut - MPT, Physical therapy 01/2002 - 12/2003 New York College of Osteopathic Medicine, Old Westbury, New York - Doctor of Osteopathic Medicine 08/2004 - 05/2009 New York College of Osteopathic Medicine, Old Westbury, New York - Master of Science, MS in Neuromusculoskeletal Science 08/2006 - 05/2009 New York College of Osteopathic Medicine, Old Westbury, New York - Predoctoral Fellowship, Co-facilitator in problem-based learning track medical school curriculum with a focus on biomedical sciences research. 08/2006 - 05/2009 Brookhaven Memorial Hospital Medical Center, Patchogue, New York - Rotating Internship 07/2009 - 06/2010 Stony Brook University Medical Center / St. Charles Rehabilitation, Department of Physical Medicine and Rehabilitation, Port Jefferson, New York - Resident 07/2010 - 06/2011 Department of Physical Medicine and Rehabilitation, Mayo School of Graduate Medical Education, Mayo Clinic College of Medicine, Rochester, Minnesota - Resident 07/2011 -

06/2013 Department of Physical Medicine and Rehabilitation, Mayo School of Graduate Medical Education, Mayo Clinic College of Medicine, Rochester, Minnesota - Fellow, Pediatric Rehabilitation Medicine 07/2013 - 06/2015

Academic Career Development Training in Policies Studies - Health Policy Fellowship American Osteopathic Association /New York College of Osteopathic Medicine 2014 - 2015 This author has no relevant disclosures.

134Hands on, Evidence Based Approach to Decreasing pain in the upper Extremity for Individuals with Spinal Cord InjuryThursday, May 03, 2018 12:45 PM - 02:15 PMLearning Objectives:1.) Describe the relationship between musculoskeletal pain and outcomes in acute and chronic spinal cord injury 2.) Demonstrate manual techniques and modalities designed to alleviate pain syndromes at the shoulder, elbow and hand/wrist 3.) Demonstrate hands-on guided movement and soft tissue interventions, including a multimodality approach to restore function and decrease pain.

Participants:1McClure I, 2Carnahan J, 2McNair K1Kessler Institution for Rehabiliation , West Orange , New jersey, USA; 2Kessler Institute for Rehabilitation , West Orange , New jersey, USAIsa McClure, PT, MAPTKessler Institution for Rehabiliation Bio:Isa A. McClure, PT, MAPT is an Advanced Clinical Specialist in Physical Therapy at the Kessler Institute for Rehabilitation, in West Orange, NJ. After receiving her Bachelor’s degrees in biology from Springfield College in 1991, she earned her Bachelor's in Health Sciences and her Masters in Physical Therapy from Touro College. She has presented extensively at both the ASIA and ASCIP meetings and served as the Committee Chair for ASIA's Rehab Standards Committee. While serving as Chair, she participated in the creation of SkinStep, an e-learning module dedicated to the prevention and treatment of pressure injuries as well as the Guide to DME for individuals with SCI/D and a guide to choosing Rehabilitation facilities for patients and their families. Education:Springfield College (Springfield, MA), BS 1987-1991 Biology Touro College (Dix Hills, NY), BS 1993-1996 Health Sciences Touro College (Dix Hills, NY), MA1993-1996 Physical Therapy

This author has the following disclosures:

Other (see below)Isa McClure is a full time Physical Therapist at the Kessler Institute for Rehabilitation and receives a salaryJanelle Carnahan, PT, DPT, ATPKessler Institute for Rehabilitation Bio:Janelle is a clinical specials physical therapist at Kessler. She has 9 years of experience treating spinal cord injuries in the acute, rehab, and outpatient settings where she developed a strong interest in the tetraplegic upper extremity. Janelle was involved in reinstituting and continues to develop the arm and hand program to best suit the patient’s needs. In addition she instituted a serial casting program for the spinal cord injury population and active member of wheelchair seating and mobility team.Education:BIOGRAPHICAL SKETCH Provide the following information for the Senior/key personnel and other significant contributors. Follow this format for each person. DO NOT EXCEED FIVE PAGES. NAME: Janelle Kenny Carnahan, PT, DPT, ATP eRA COMMONS USER NAME (credential, e.g., agency login): POSITION TITLE: Clinical Specialist Spinal Cord Injury and Ventilator Dependent Spinal Cord Injury, Kessler Institute for Rehabilitation

EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, include postdoctoral training and residency training if applicable. Add/delete rows as necessary.) INSTITUTION AND LOCATION DEGREE (if applicable) Completion Date MM/YYYY FIELD OF STUDY

Sacred Heart University, Fairfield, CT BS- Psychology 2006 Psychology Sacred Heart University, Fairfield, CT DPT 2008 Physical Therapy

NOTE: The Biographical Sketch may not exceed five pages. Follow instructions below. A. Personal Statement The main areas of focus have been in clinical rehabilitation related to spinal cord injury with special focus on upper extremity management and seating and positioning. I have also contributed to research that directly relates to improving the care of persons with spinal cord injury and other disabilities. B. Positions and Honors Positions and Employment (Since 2011) 2008-2010 Physical Therapist, Helen Hayes Hospital, West Haverstraw, NY

2010-2013 Physical Therapist, Shepherd Center, Atlanta, GA 2013-2014 Physical Therapist, Mount Sinai Hospital, New York, NY 2014-Present Physical Therapist, Kessler Institute for Rehabilitation, West Orange, NJ

Certification: a. New Jersey State Licensure, Physical Therapy, 2014-present b. New York State Licensure, Physical Therapy , inactive (acquired in 2008) c. Georgia State Licensure, Physical Therapy, inactive (acquired in 2010)

Clinical License: New Jersey. 40QA01542800 C. Contribution to Science • ”Pressure relief behaviors and weight shifting activities to prevent pressure ulcers in persons with SCI” 2015-present D. Additional Information: Research Support and/or Scholastic Performance

Research Support (Active) This author has the following disclosures:

Other (see below)Janelle Carnahan is a part time Physical Therapist at the Kessler Institute for Rehabilitation and receives a salaryKeara McNair, MS, OTR/L, BCPRKessler Institute for Rehabilitation Bio:Short bio: Keara McNair began her career at Medstar National Rehabilitation Hospital on general medicine, pediatric, and spinal cord injury units. She developed her practice further into a focus of working with patients with motor complete spinal cord injuries, particularly C4-C6 tetraplegia, including use of environmental controls, advanced home modifications, and durable medical equipment for this population. She began working at Kessler West Orange in 2014 after completing a month long 200- hour yoga teacher training at the Integral Yoga Institute in Buckingham, Virginia. At Kessler, she was additionally trained in ventilator care. She has been responsible for running the Arm Hand Program to address upper extremity management of patients with incomplete tetraplegia and presented on her success with the program at the Annual ASIA Scientific Meeting in April 2016. She is the co- lead of Kessler’s EADL program and presented at the ASCIP conference in 2017 on integrating consumer- based technology into an EADL program.Education:Education: University at Buffalo, The State University of New York. Masters in Occupational Therapy (June 2011). University at Buffalo, The State University of New York. Bachelors in Occupational Science (June 2011). This author has the following disclosures:

Other (see below)

Keara McNair is a full time OccupationalTherapist at the Kessler Institute for Rehabilitation and receives a salary

135Advancements in our understanding of manual wheelchair biomechanics: Daily life and SportThursday, May 03, 2018 03:45 PM - 05:15 PMLearning Objectives:1. Describe tools and methods to measure wheelchair biomechanics (kinematics and kinetics) outside of the laboratory 2. Describe the impact of wheelchair configuration on propulsion technique 3. Describe tools and methods to measure wheelchair racing mechanics

Participants:1Morrow M, 2McNitt-Gray J, 3Rice I1Mayo Clinic , Rochester , MN, USA; 2Usc , Los Angeles , CA, USA; 3University of Illinois Urbana-Champaign , Champaign , Illinois, USAMelissa Morrow, PhDMayo Clinic Bio:Dr. Melissa (Missy) Morrow is an Assistant Professor of Biomedical Engineering and Associate Consultant in the Health Sciences Research Department.

Dr. Morrow is from Houston, Texas. She earned her undergraduate in Biomedical engineering from Tulane University in 2003, her master’s degree in clinical and translational research, and her PhD in Biomedical Sciences and Biomedical Engineering through the Mayo Clinic Graduate School. She was a post-doctoral research fellow on Dr. Jeffrey Basford’s T32 in rehabilitation research at Mayo for two years, followed by serving two years as a research scholar on an NIH K12 career award.

Dr. Morrow’s current research program is focused on secondary conditions of spinal cord injury and remote monitoring in health care. She regularly serves on the NIH Musculoskeletal Rehabilitation Sciences Study section as an ad hoc member. Dr. Morrow's research is funded by the Neilsen Foundation, the NIH (NICHD R01, NIA R01, and NIA R21) and a Department of Defense CDMRP award.Education:Tulane University, New Orleans, Louisiana - BSE, Biomedical Engineering 08/1999 - 05/2003

Mayo Graduate School, Mayo Clinic College of Medicine, Rochester, Minnesota— Doctor of Philosophy in Biomedical Sciences-Biomedical Engineering 06/2004 - 09/2009

Department of Orthopedic Surgery, Rochester, Minnesota - Post Doctoral Fellowship, NIH T32 Rehabilitation Training Fellow 10/2009 - 10/2011

Department of Orthopedic Surgery, Rochester, Minnesota - Research Scholar, NIH K12 Career Development Program, Building Interdisciplinary Research Careers inWomen's Health (BIRCWH) Scholar, Women's Health Research Center 10/2011 - 10/2013

Mayo Graduate School, Mayo Clinic College of Medicine, Rochester, Minnesota— Masters in Clinical and Translational Science 11/2011 - 12/2013This author has the following disclosures:

Research SupportDr. Morrow is employed by Mayo Clinic Department of Health Sciences Research an an Associate Consultant I and receives a salary. The work being presented was supported by NIH NICHD and the Neilsen Foundation. Jill McNitt-Gray, PhDUsc Bio:Jill L. McNitt-Gray, Ph.D. is a Gabilan Distinguished Professor in Science and Engineering and mentors students the Departments of Biological Sciences and Biomedical Engineering at the University of Southern California. She is also the Director of the USC Biomechanics Research Laboratory and was the founding director of a cross-cutting interdisciplinary graduate program in biological sciences at USC.

Dr. McNitt-Gray’s interdisciplinary research focuses on the neuromuscular control and dynamics of human movements and aims to identify risk factors and develop effective methods in rehabilitation engineering and performance enhancement for individuals with various ability levels (clinical populations as well as elite athletes). She uses both experimental and dynamic modeling approaches to test research hypotheses specific to control priorities during physically-demanding well-practiced tasks. Her research has been funded by Department of Defense, National Science Foundation, National Institutes of Health, Veterans Administration, and national governing bodies of sport including the Medical Commission of the International Olympic Committee and the United States Olympic Committee.

Dr. McNitt-Gray earned her undergraduate degree in mathematics and statistics with a certification in coaching from Miami University in Oxford, Ohio in 1980. After working in load research and load management for the American Electric Power Service Corporation, she returned to graduate school at the University of North Carolina, Chapel Hill. In 1985, she earned her master’s degree in biomechanics at the University of North Carolina at Chapel Hill under the mentorship of Barney LeVeau PT PhD and was the assistant coach of the Carolina Women’s Gymnastics team. Dr. McNitt-Gray received her doctoral degree in biomechanics from Penn State under the mentorship of Richard Nelson and Peter Cavanagh in 1989.

Dr. McNitt-Gray has served on the Editorial Board of the International Journal of Sports Biomechanics and the Journal of Applied Biomechanics and as an ad hoc reviewer on study sections for NIH, NSF, CDC, and various governing bodies of sport. She served on the ASB membership committee from 1989-92, and then as a member of the education committee. Dr.

McNitt-Gray has served on the Executive Board as Education Chair (1993-95), Program Chair (2002), and as President (2009-2012). Dr. McNitt-Gray also served as a member of the Executive Council of the ISB from 2001 to 2007 and served as the ISB Liaison to Affiliated and Economically Developing Societies. Dr. McNitt-Gray has received the USC Mellon Culture of Mentoring Award for her work with the Women in Science and Engineering program (WiSE) and a USC Mellon Mentoring award for her mentoring of undergraduate students. The Medical Commission of the International Olympic Committee recognized her research team’s work in the physical sciences with the Prince Alexandre de Merode Award. Dr. McNitt-Gray is also actively involved in translation of science into the practice and outreach programs that provide informal educational experiences in Science, Technology, Engineering and Mathematics fields. Her innovative approaches to research and education have been recognized by the USC Center for Excellence in Teaching and funded by the National Science Foundation. She has served as a biomechanist for the International Olympic Committee, the US Olympic Committee, multiple National Governing Bodies of Sport, and the National Collegiate Athletic Association.Education:1985-1989 Ph.D. Degree, The Pennsylvania State University, University Park, PA. Major Area: Biomechanics Related Areas: Motor Performance, Engineering, Exercise Physiology, Anatomy

1983-1985 M.A. Degree, The University of North Carolina, Chapel Hill, NC. Major Area: Biomechanics Minor Areas: Physical Therapy, Motor Performance, Anatomy, Exercise Physiology

1981-1982 Graduate Applied Statistics Courses, Ohio State University, Columbus, OH. Areas of Study: Experimental Design, Regression, Multivariate, Nonparametric Analysis 1976-1980 A.B. Degree, Miami University, Oxford, OH. Major Area: Mathematics andThis author has the following disclosures:

Research SupportDr. McNitt-Gray is employed by USC in the Departments of Biological Sciences an Biomedical Engineering as a Professor and receives a salary. She is funded by the DoD and the Rancho Los Amigos Research Institute. Ian Rice, PhDUniversity of Illinois Urbana-Champaign Bio:Assistant Professor, Department of Kinesiology and Community Health Sciences, at the University of Illinois, Urbana Champaign. Ian earned his PhD from the University of Pittsburgh in 2010 in rehabilitation science and technology with a focus on biomechanics. His research interests include the study of interventional and adaptive technologies to promote injury prevention, physical activity, and full life participation in persons with mobility limitations. Dr. Rice has a particular interest in combining motor learning, motor control, and ergonomics to optimize the match between person and mobility technology in the contexts of everyday life and adapted sports. Education:PhD. Rehabilitation Science and Technology 2010

University of Pittsburgh

M.S. Occupational Therapy 2002 Washington University School of Medicine

B.S. Psychology 1999 University of Illinois, Champaign Urbana, IL This author has the following disclosures:

Research SupportDr. Rice is employed by the the University of Illinois Urbana-Champaign in the Department of Kinesiology and Community Health as an Assistant Professor and receives a salary. His research is funded by the the University of Illinois and the Paralyzed Veterans of America.

136Advancements in our understanding of manual wheelchair biomechanics: Functional TasksThursday, May 03, 2018 03:45 PM - 05:15 PMLearning Objectives:1. Describe how trunk posture modifications during propulsion may reduce risk of damage to the rotator cuff

2. Describe recommendations for safe and effective body transfers and wheelchair frame loading

3. Describe how pediatric wheelchair propulsion mechanics compare to to adult wheelchair propulsion mechanics

Participants:1Cloud B, 2Koontz A, 3Requejo P, 4Slavens B1Mayo Clinic , Rochester , MN, USA; 2University of Pittsburgh , Pittsburgh , PA, USA; 3Rancho Los Amigos National Rehabilitation Center , Downey , CA, USA; 4University of Wisconsin Milwaukee , Milwaukee , WI, USABeth Cloud, PT, DPT, PhDMayo Clinic Bio:Beth Cloud is an assistant professor in the Physical Therapy Doctoral Program at Mayo Clinic. She is a 2010 graduate of the same program. She completed a Ph.D. in Clinical and Translational Science from the Mayo Clinic Graduate School of Biomedical Sciences in 2015 with a thesis evaluating spine and shoulder motion during manual wheelchair propulsion. Dr. Cloud's primary research interests are the evaluation of upper limb biomechanics and the characterization and treatment of secondary conditions following neurological injury. She works collaboratively with a multidisciplinary team in the Rehabilitation Medicine Research Center to execute this research agenda. Dr. Cloud's teaching interests include anatomy, neuroscience, neurorehabilitation, biomechanics, and research topics. Clinically she works in neurorehabilitaiton, primarily treating patients in an acute setting.

Education:Anatomy Training Program, Anatomical Society & American Association of Anatomists; Certificate (2014-2017)

Mayo Clinic Graduate School of Biomedical Sciences, Rochester, MN; Ph.D., Clinical and Translational Science (2010-2015)

Mayo Clinic School of Health Sciences, Rochester, MN; Doctor of Physical Therapy (2007-2010)

Augustana College, Rock Island, IL; B.A., Psychology & Biology (2003-2007) This author has the following disclosures:

Research SupportDr. Beth Cloud is an Assistant Professor at Mayo Clinic in the PT Doctoral program at Mayo Clinic and receives a salary. Her research is funded through Mayo Clinic and the Craig H. Neilsen Foundation. Alicia Koontz, PhD, RETUniversity of Pittsburgh Bio:Alicia M. Koontz, PhD, RET is the Associate Director for Research at the Human Engineering Research Laboratories, VA Pittsburgh HealthCare System and an Associate Professor at the University of Pittsburgh. She received her PhD degree in Rehabilitation Science from the University of Pittsburgh and B.S. and M.S. degrees in Biomedical Engineering from Wright State University. Dr. Koontz’s research is aimed towards improving the health, function and quality of life of wheelchair users. She has expertise in the areas of rehabilitation biomechanics, assistive technology, and secondary injury prevention. Dr. Koontz has a 12 year track record of grant funding from sources including the VA, NIH, and the PVA and has authored over 100 peer-reviewed journal articles, conference proceedings and book chapters. Education:08/2001 PhD in Rehabilitation Science (Rehabilitation Engineering) University of Pittsburgh, Pittsburgh, PA

06/1994 MS in Biomedical Engineering (Rehabilitation Engineering) Wright State University, Dayton, OH

06/1993 BS in Biomedical Engineering Wright State University, Dayton, OH This author has the following disclosures:

Research SupportDr. Alicia Koontz is an Associate Professor at the University of Pittsburgh and receives a salary. Her research is funded by the DoD, NIH, NSF, and the Paralyzed Veterans of America. Philip Requejo, PhDRancho Los Amigos National Rehabilitation Center Bio:Dr. Requejo has 20 years of technology and engineering-based experience in rehabilitation of

children and adults aimed to enhance health and function and promote social participation. His research is at the interface of engineering, neuroscience, and rehabilitation where he has focused on the development and delivery of cutting-edge technologies for identification, evaluation, and rehabilitation of motor processes to enhance the quality of life in those with disabilities. Dr. Requejo's research primarily falls into several broad areas of rehabilitation engineering and biomechanics research; focusing on the design, analysis, and implementation of technologies to preserve and enhance mobility in those with severe disabilities, including spinal cord injury, stroke, cerebral palsy, traumatic brain injury, and other neurological diseases.Education:1996-2002: PhD. University of Southern California, Los Angeles, CA. Discipline: Kinesiology/Biomechanics/Engineering

1988-1993: B. S. (Cum Laude) California State University, Long Beach, Long Beach, CA. Major Area: Electrical Engineering with emphasis on DigitalSystems, Controls, and Biomedical EngineeringThis author has the following disclosures:

Research SupportDr. Philip Requejo is a Director of the Engineering Rehab program at Rancho Los Amigos and receives a salary. His research is funded by the DoD, NIDILRR, and the Craig H. Neilsen Foundation. Brooke Slavens, PhDUniversity of Wisconsin Milwaukee Bio:Brooke Slavens’ research interests include upper extremity motion analysis, inverse dynamics modeling, rehabilitation engineering and orthopaedic biomechanics. She is currently investigating upper extremity dynamics during crutch, walker and wheelchair mobility in children and adults with orthopaedic disabilities.

New interests in human motion analysis have directed research to the area of upper extremity. To quantify the upper extremity, the Movement Analysis for Biomedical Innovation & Technology (Mobility) Lab has developed a validated 3D inverse dynamics model for assessment of pediatric mobility. The model can be used to characterize shoulder, elbow and wrist joint forces and moments. It is being applied to subjects with myelomeningocele, cerebral palsy, spinal cord injury and osteogenesis imperfecta to characterize crutch, walker and wheelchair mobility to better understand joint load demands. Due to long-term assistive device usage, these mobility device users may be at an increased risk for developing upper extremity pain or pathologies.

Further research interests include musculoskeletal and finite element modeling to investigate the tissue level effects of long-term joint loading from assistive device usage. Research may improve clinical intervention strategies, therapeutic gait planning and offer insight to long-term joint loading effects.Education:NIDRR ARRT Postdoctoral Training Pediatric Mobility Marquette University 2010

Ph D Biomedical Engineering Marquette University 2007

MS Biomedical Engineering Marquette University 2004

BS Biomedical Engineering University of Iowa 2001This author has the following disclosures:

Other (see below)Dr. Slavens is an Associate Professor at the University of Wisconsin Milwaukee and receives a salary.

137Motherhood after spinal cord injury: lactation, breastfeeding and autonomic dysreflexia: knowledge to practiceThursday, May 03, 2018 03:45 PM - 05:15 PMLearning Objectives:On completion of this course, participants will be able to: 1) Explain the SCI-related challenges and barriers that prospective mothers face during lactation and breastfeeding 2) Discuss the special considerations that must be made for postpartum care and breastfeeding with SCI 3) Understand the resources and guidelines available to provide their patients with information, and how to utilize evidence-based recommendations to provide postpartum care, including: management of Autonomic Dysreflexia, facilitating breastfeeding for mothers with SCI who choose to do so and connecting them with an interdisciplinary team of professionals who can provide support in the areas of lactation, psychological wellbeing, independent living, rehabilitation and activities of daily living

Participants:1Lee A, 2Elliott S, 3Hocaloski S, 4Hodge K, 1Krassioukov A1International Collaboration on Repair Discoveries (Icord), Faculty of Medicine, University of British Columbia , Vancouver , BC, Canada; 2University of British Columbia, Bc Centre for Sexual Medicine, Vancouver Sperm Retrieval Clinic, Prostate Cancer Supportive Care Clinic , Vancouver , BC, Canada; 3Gf Strong Rehabilitation Centre , Vancouver , BC, Canada; 4Sunny Hill Health Centre , Vancouver , BC, CanadaAmanda Lee, BScInternational Collaboration on Repair Discoveries (Icord), Faculty of Medicine, University of British Columbia Bio:Amanda Lee is a MSc student in Experimental Medicine at the University of British Columbia who is supervised by Dr. Krassioukov and supported by a Canadian Institutes of Health Research (CIHR) CGS-M scholarship. Amanda previously completed her BSc in Psychology at the University of British Columbia, where she conducted both basic sciences research using rodent models and clinical studies. She studies the impact of spinal cord injury on motherhood, with a specific interest lactation and breastfeeding outcomes. Her Master's work involves studying

quality of life and breastfeeding success in mothers with SCI and creating evidence-based recommendations for improved clinical care of mothers with SCI in the postpartum.Education:University of British Columbia (Vancouver, BC, Canada), BSc 2010-2015, Psychology

University of British Columbia (Vancouver, BC, Canada), MSc 2016-present, Experimental MedicineThis author has the following disclosures:

Research SupportAmanda is recipient of a Master's student scholarship from the Canadian Institutes of Health Research (CIHR).Stacy Elliott, BA, MDUniversity of British Columbia, Bc Centre for Sexual Medicine, Vancouver Sperm Retrieval Clinic, Prostate Cancer Supportive Care Clinic Bio:Dr. Stacy Elliott is a Clinical Professor in the Departments of Psychiatry and Urologic Sciences, and Principal Investigator and Faculty member at International Collaboration on Repair Discoveries (ICORD), University of British Columbia (UBC), and the Medical Manager of the BC Center for Sexual Medicine, Co-Director for the Vancouver Sperm Retrieval Clinic, and has a specialized interest in neurological disability. She has been on international panels and developed practice guidelines for SCI as well as a Pregnancy and Spinal Cord Injury information booklet and university course on women, pregnancy, delivery and lactation. Internationally she is a recognized sexual medicine expert in SCI, with numerous national and international conference presentations and several peer reviewed publications and invited book chapters. As a sexual medicine physician she assesses and manages the sexual and reproductive consequences of medical or surgical problems, particularly neurological disability. The Sexual Health Clinic at ICORD in Vancouver is responsible for over 150 live births following neurological disability in men and Dr. Elliott has written numerous articles and book chapters on sexual and fertility rehabilitation after spinal cord injury (sperm retrieval and autonomic dysreflexia). She has been an invited author for the Paralyzed Veterans of America Clinical Practice Guidelines: Sexuality and Reproductive Health in Adults with Spinal Cord Injury which are referenced internationally by health care professionals (http://www.pva.org) and Advisory Board Member, American Spinal Injury Association (ASIA), International Autonomic Standards Committee. In addition to being an international speaker and teacher and board member, she is involved in physical medicine and rehabilitation, gynecology, urology, nursing, occupational and physical therapists. Dr. Elliott teaches undergraduate medical school students as well as residents in psychiatry, urology and physiatry at UBC as well as practicing community physicians and specialists. Her teaching includes being an author of university course development: Two 3 credit BC Institute of Technology (BCIT) for sexual rehabilitation for health care professionals in order to better prepare them for dealing with sexuality, fertility and disability (http://www.bcit.ca/health/industry/sexualrehab.shtml). In 2009, Dr. Elliott and colleagues collaborated on the publication of a sexual device manual aimed at persons with neurological disability which is downloadable worldwide, Title: PleasureAble http://www.dhrn.ca/files/sexualhealthmanual_lowres_2010_0208.pdf). Krassioukov, A., MacHattie, E., Naphtali, K., Miller, W.C., and Elliott, S.. (2009). PleasurAble: Sexual Device

Manual for Persons with Disabilities and also on a Practical Guide for Pregnancy and Delivery for women with SCI.

Currently she is investigating techniques of sensory substitution and neuroplasticity regarding sexual function ( Borisoff J, Elliott S, Hocaloski S, Birch G. The development of a sensory substitution system for the sexual rehabilitation of men with chronic spinal cord injury. J Sex Med. 2010 Nov;7(11):3647-58) and autonomic dysreflexia with sexual activity and vibrostimulation

Education:University of British Columbia / BA / 1976-1980 / Human Nutrition

University of British Columbia / MD / 1980-1985 / Medicine

Royal Columbian Hospital, BC / Internship / 1985-1986 / Rotating Internship

Sexual Medicine Unit, Shaughnessy Hospital / Fellowship / 1986-1988 / Fellowship in Sexual MedicineThis author has the following disclosures:

Speaker Bureau Research Support

ONGOING RESEARCH SUPPORT:

1. Craig H. Neilsen Foundation QOL Project Grants. Motherhood after spinal cord injury: lactation, breastfeeding, and autonomic dysreflexia. Period: 2016-2017 PI: Dr. A. Krassioukov ROLE: Co-Investigator

2. Rick Hansen Institute. Title: Development of a mobile app (telephone/iPod application) for emergency department physicians on recognition and management of life threatening episodes of autonomic dysreflexia: “ABC of AD for the EM doc”. Period: Apr 2015-Dec 2016. PI: Dr. A. Krassioukov. ROLE: Co-PI

3. Rick Hansen Foundation/International Collaboration On Repair Discoveries (ICORD)/Seed Grants. Title: Development of evidence-based guidelines for blood pressure management during iatrogenically-induced autonomic dysreflexia in those with spinal cord injury: the limits of cerebral autoregulation. Period: Apr 2014-Jun 2016. ROLE: PI

COMPLETED RESEARCH SUPPORT: 1. Rick Hansen Institute. Title: Perinatal Care of Women with Spinal Cord Injury – Workshop to develop Consensus for Research, Clinical and Policy Implications. Period 2014-2015. PI: M. Basso ROLE: Co-Investigator

2. GF Strong Foundation. Title: Validation of the International Autonomic Standards of Evaluation of Individuals with Chronic Spinal Cord injury: Focus on Sexual, Bladder and Bowel Function. Period 2013-2015. PI: Dr. M. Carlson ROLE: Co-Investigator

Disclosures Speaker Bureau: Sanofi and Mylan speaker and CME developmentShea Hocaloski, RN, BTechNGf Strong Rehabilitation Centre Bio:Shea Hocaloski is a rehabilitation nurse and sexual health clinician who specializes in sexual health rehabilitation. She has extensive experience working with patients with SCI during both the pregnancy and postpartum stages. As one of the experts on the panel for the Craig H Neilsen Foundation Quality of Life grant, she played a major role in patient outreach in addition to helping develop the surveys used and evaluating the findings. Previously, she was also involved in the development of the Pregnancy and Spinal Cord Injury booklet and brochure which has been disseminated to patients at the Sexual Health Clinic at Vancouver General Hospital. She will be one of the presenters at the conference workshop, speaking on her work in sexual health and special considerations to be made for women with SCI who choose to breastfeed.Education:British Columbia Institute of Technology (Burnaby, BC, Canada) RN, 2002, Bachelor of Technology in Nursing

This author has the following disclosures: Consultant

Shea is listed as a working expert on the project "Motherhood after spinal cord injury: lactation, breastfeeding and autonomic dysreflexia" and receives consultant fees (upper limit of $3000 over the entire project duration) for her expertise and involvement with project development. Shea is employed as a Sexual Health Nurse at the GF Strong Rehabilitation Centre in Vancouver, BC, Canada.Karen Hodge, MSW, RCSWSunny Hill Health Centre Bio:Karen Hodge, MSW, RCSW is a Registered Clinical Social Worker in a pediatric hospital setting. Karen completed her Bachelor of Arts degree at Saint Mary’s University in Halifax, NS in 2000. She went on to complete her Bachelor of Social Work degree at Carleton University in Ottawa, ON in 2001 and her Master of Social Work degree at the University of British Columbia in 2005. Karen received the Rick Hansen Man in Motion Fellowship during her graduate studies at UBC. Karen’s area of focus has been in health care and working with persons with medical, developmental and physical challenges. In 2016, Karen was the winner of the Inspiring Social Worker of the Year award, a provincial award established in partnership by the BC Association of Social Workers and the UBC School of Social Work to recognize social workers in British Columbia whose professional and personal efforts and dedication to serving people from

marginalized communities has inspired others to care and contribute to the promotion of social justice.

Karen’s spinal cord injury occurred at age 15. She is the mother of two young children and is a founding member of the Spinal Cord Injury Perinatal Interest Group (SCI -PIG) established in 2013. This is a multi-disciplinary (nurses, researchers, physician, and mother with a SCI) with representation from multiple agencies (Spinal Cord Injury BC, BC Women’s Hospital, Vancouver Coastal Health). This small, dedicated group strives to identify the key barriers and gaps in knowledge about pregnancy and spinal cord injury, and works to raise awareness amongst clinicians and women with spinal cord injury about the potential to have children after spinal cord injury.

Karen has completed additional training to enhance skills when working with prospective or current parents including postpartum doula training, breastfeeding training (supportive of all modes of feeding that best meet the child and the mother’s needs), training related to the facilitation of postpartum support groups, as well as coursework related to addressing the symptoms of depression and anxiety. In 2014 Karen completed all training and supervision requirements and successfully wrote the Association of Social Work Boards, Clinical Social Worker Licensing Exam (2014). A Registered Clinical Social Worker (RCSW) is a separate class of the Registered Social Worker designation which recognizes advanced practice skills in mental health and clinical social work, typically counselling and psychotherapy, human development, and mental health disorders. RCSWs are authorized in the province of British Columbia to use and apply the Diagnostic and Statistical Manual of Mental Disorders (DSM-V).

Karen has presented at international, national and local conferences and for various community groups. Karen has worked as a sessional lecturer within the School of Social Work at the University of British Columbia on the topic of Disability and Social Policy as well as having been invited as a guest speaker to numerous classes from the intro level to the masters level to present on the topic of disability and social work practice. Education:University of British Columbia (Vancouver, BC), 2005, Master of Social Work

Carleton University (Ottawa, ON), 2001, Bachelor of Social Work

Saint Mary’s University (Halifax, Nova Scotia), 2000, BAThis author has the following disclosures:

ConsultantKaren is listed as a working expert on the project "Motherhood after spinal cord injury: lactation, breastfeeding and autonomic dysreflexia" and receives consultant fees (upper limit of $3600 over the entire project duration) for her expertise and involvement with project development. Andrei Krassioukov, MD, PhD, FRCPCInternational Collaboration on Repair Discoveries (Icord), Faculty of Medicine, University of British Columbia Bio:PERSONAL STATEMENT:

Both my research and clinical work are related to spinal cord injury, autonomic dysfunctions, and disability issues. As a leader in a distinct and specialized field, I have published 90 peer-reviewed publications in the past five years, which have collectively been cited over 437 times with an h-index of 31 (Web of Science). I was the PI on 78 of these publications, with my trainees as first authors on 49 of them. I have received a number of recognition for the best published research in the area of SCI (ASIA Awards 2003, 2014). Also during the past five years I have provided 69 invited/plenary/keynote addresses at international and national meetings (e.g., International Society of Physical Medicine Association, Latin American Congress of PM&R, etc.). In recognition of research excellence and leadership I was elected a Fellow of the Canadian Academy of Health Science in 2010.

CURRENT DUTIES: Presently, I am a Professor of Medicine and Chair of Rehabilitation Medicine at the University of British Columbia and a staff physician at the spinal cord injury (SCI) program at the GF Strong Rehabilitation Centre in Vancouver. I am also a head of the Autonomic Dysfunctions Laboratory and Co-Director of ICORD, Vancouver. As a clinician-scientist I spend approximately 60% of my time with my research and 40% with my clinical duties. Both my research and clinical work are related to spinal cord injury, autonomic dysfunctions and disability issues. Presently, I am a primary research supervisor of three postdoctoral fellows, one medical residents, one MD-PhD student, one PhD student, two master students, and four medical students. Experimental animal, human clinical studies, and knowledge translation research are incorporated in ongoing projects in my laboratory.

CONTRIBUTION TO SCIENCE: The following are my most significant knowledge translation contributions to the field of spinal cord injury: • My award winning CIHR-funded “ABC of AD”, an educational web-based program for paramedics won 2 awards from the 2013 Horizon Interactive Awards, and is currently being considered for inclusion in the BC Ambulance Service’s curriculum. The program is designed to empower first responders with evidence-informed disease managements approaches. • I developed the International Autonomic Standards after SCI, and implemented these standards around the world to improve evidence-informed healthcare practices. • My research on the effect of autonomic dysfunction on exercise performance in athletes with SCI has led to the creation of autonomic assessments for athletes, which are currently being proposed to the IPC for inclusion into their classification. These issues have also been communicated to the community via a 2012 CIHR-funded Café Scientifique and represent a major contribution to health care focused on prevention and management of secondary conditions after SCI. • I published the “direly needed” book PleasureAble, which focused on sexual activity after SCI and other disabilities and has received significant international attention.Education:Volgograd State Medical Institute (Volgograd, Russia) MD (June 1979) Medicine

Pavlov Institute of Physiology, The Academy of Sciences of Russia (St. Petersburg, Russia), PhD (April 1983), Medicine/Neurophysiology

P. Robarts Research Institute (London, ON, Canada) Fellow (Aug 1991- Sep 1994), Spinal Cord Injury, Neurophysiology

University of British Columbia, FRCPC (Vancouver, BC, Canada) June 2006, Board Examinations in Physical Medicine and RehabilitationThis author has the following disclosures:

Research Support Other (see below)

Dr. Krassioukov is Principle Investigator on the project "Motherhood after spinal cord injury: lactation, breastfeeding and autonomic dysreflexia" through which the evidence for the proposed course was developed. The project was funded by the Craig H Neilsen (CNF) Foundation via a Quality of Life grant.

ONGOING RESEARCH SUPPORT 1. Craig H. Neilsen Foundation QOL Project Grants. Title: Motherhood after spinal cord injury: lactation, breastfeeding, and autonomic dysreflexia. Period: 2016-2017 ROLE: PI

2. Heart and Stroke GIA 2016/17. Title: When are blood vessels “ready to rupture”? Cerebrovascular health following spinal cord injury: from animal models to clinical practice. Period: 2016 – 2019 ROLE: PI

3. Pfizer Canada Inc. Title: A Phase II, Open-Label Exploratory Study Investigating the Efficacy of Toviaz for Treatment of Adult Patients with Spinal Cord Injury (SCI) with Neurogenic Detrusor Overactivity (NDO) for Amelioration of Autonomic Dysreflexia (AD). Period: Nov 2015 –Feb 2017 ROLE: PI

4. Rick Hansen Institute. Title: Development of a mobile app (telephone/iPod application) for emergency department physicians on recognition and management of life-threatening episodes of autonomic dysreflexia: “ABC of AD for the EM doc”. Period: Apr 2015-Dec 2016. ROLE: PI

5. Vancouver Foundation. Title: Vancouver Foundation Start-up Funds: Period: April 2015 – March 2017 ROLE: PI

6. Christopher and Dana Reeve Foundation. Title: Big Idea Cardiovascular Committee. Period: Feb 2015-Aug2015. ROLE: PI

7. Rick Hansen Institute/ RHI Pilot Studies - Optimizing Neurorecovery Following SCI. Title: Effect of epidural stimulation on cardiovascular control following spinal cord injury. Period: Mar 2015-Mar 2017.

ROLE: PI

8. Rick Hansen Foundation/International Collaboration On Repair Discoveries (ICORD)/Seed Grants. Title: Development of evidence-based guidelines for blood pressure management during iatrogenically-induced autonomic dysreflexia in those with spinal cord injury: the limits of cerebral autoregulation. Period: Apr 2014-Jun 2016. PI: Dr. Stacy Elliott. ROLE: Co-Investigator

9. Department of Defense USA. Title: Alleviating autonomic dysreflexia after spinal cord injury. Period: September 2014-August 2017. ROLE: PI

10. Craig H. Neilsen Foundation/ Neilsen Senior Research Grant. Title: Cardiac function after spinal cord injury: from bench to bedside. Period: July 2013-June 2017. ROLE: PI 11. Rick Hansen Institute. Title: Validation of the International Autonomic Standards for evaluation of individuals with chronic spinal cord injury. Period: March 2013- March 2017. ROLE: PI

12. Rick Hansen Foundation. Title: Improving Cardiovascular Health for Canadians Living with SCI: Effects of Exercise, sex Differences, and Targeted Clinical Education. Period: April 2012-March 2017. ROLE: PI

13. Rick Hansen Institute / Operating Grant. Title: BOTOX treatment for neurogenic detrusor hyperreflexia and prevention of autonomic dysreflexia following spinal cord injury. Period: July 2012 – Jan. 2017. ROLE: PI

14. Canadian Institutes of Health Research (CIHR) / Chronic disease risk and intervention strategies team grant. Title: Improving cardiovascular health for Canadians living with spinal cord injury: effects of exercise and targeted education. Period: Dec. 2011-Nov. 2016. ROLE: PI

15. Craig H. Neilsen Foundation/Christopher and Dana Reeve Foundation. Title: Recovery of cardiovascular function with epidural stimulation after human spinal cord injury. Period: January 2015-December 2017. PI: Dr. Susan Harkema ROLE: Co-Investigator

16. Canadian Institutes of Health Research (CIHR) / Operating grant. Title: Beyond VO2peak: Understanding exercise-induced changes in cardiovascular function after

stroke. Period: 2011-2015. PI: Dr. J. Eng ROLE: Co-Investigator

17. International Spinal Research Trust / Operating grant. Title: Peripheral Sympathetic and sensory plasticity in bladder and bowel circuitry in chronic spinal cord injury. Period: Jan. 2011-Aug. 2014. PI: Dr. M. Ramer ROLE: Co-Investigator

18. Rick Hansen Institute Start Up Funds. Title: Rick Hansen Institute Start-Up Funds. Period: March 2007 – March 2020. ROLE: PI

OTHER

Coloplast and WellSpect

138The continued evolution of ISNCSCI – an interactive updateThursday, May 03, 2018 03:45 PM - 05:15 PMLearning Objectives:- To discuss consideration for changes and additions to the International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI) being deliberated in the International Standards Committee. - To provide feedback on proposed ISNCSCI updates. - To identify needs for ISNCSCI clarifications, future topics and priorities.

Participants:1Rupp R, 2Kirshblum S, 3Tansey K, 4Burns S1Heidelberg University Hospital - Spinal Cord Injury Center , Heidelberg , BW, Germany; 2Kessler Institute for Rehabilitation , West Orange , NJ, USA; 3University of Mississippi Medical Center , Jackson , MS, USA; 4Spinal Cord Injury Service, Va Puget Sound Health Care System , Seattle , WA, USARuediger Rupp, Dr.-Ing.Heidelberg University Hospital - Spinal Cord Injury Center Bio:Ruediger Rupp received the Dipl.-Ing. degree in electrical engineering with focus on biomedical engineering and his Ph.D. degree from the Technical University of Karlsruhe, Germany, in 1994 and 2008, respectively. After working at the Institute for Biomedical Engineering and Biocybernetics (Prof. G. Vossius) until 1996, since 1997 he is with the Spinal Cord Injury Center (Head: Prof. N. Weidner) of Heidelberg University Hospital, Germany, where he holds the position as the head of the Experimental Neurorehabilitation group.

His main research interests are in the field of rehabilitation engineering for spinal cord injured patients. This includes neuroprosthetics mainly of the upper extremity, man-machine interfaces, gait analysis, development and clinical validation of novel methods and devices for locomotion therapy and realization of software projects for standardized documentation of rehabilitation outcome. He is author of more than 200 journal, book and conference abstracts and holds two patents. He has been awarded several times for his work and is a member of IEEE, IFESS, VDE, DMGP, DGOOC, ISCoS and ASIA. Education:1989 - 1994 Electrical engineering, Technical University of Karlsruhe, GermanyThis author has the following disclosures:

Other (see below)Chair of the International Standards Committee, ASIASteven Kirshblum, MDKessler Institute for Rehabilitation Bio:Dr Kirshblum is a Senior Medical Officer and Director of SCI Services at Kessler Institute for Rehabilitation in West Orange NJ, and is a Professor and Chair of Physical Medicine and Rehabilitation at Rutgers New Jersey medical School. He also serves as the Chief Academic Officer for the Select Medical Rehabilitation Division and Chief Medical Officer for the Kessler Foundation. Education:Fairleigh Dickinson University (Teaneck, NJ), BS- Biology, 1981 University of Health Sciences/Chicago Medical School (N. Chicago, IL), MD, 1986 St Francis Hospital (Evanston, IL), Internship Physical Medicine and Rehabilitation (PM&R), 1987 Mount Sinai Medical Center (NY, NY), Residency PM&R, 1990 This author has the following disclosures:

Other (see below)Board Liaison of the International Standards Committee, ASIA Board of Directors, ASIAKeith Tansey, MD, PhDUniversity of Mississippi Medical Center Bio:Keith E. Tansey, MD, PhD, is a Senior Scientist in the NeuroRobotics Lab and the Center for Neuroscience and Neurological Recovery at Methodist Rehabilitation Center, a Professor in the Departments of Neurosurgery and Neurobiology and Anatomical Science and lead faculty of the Neurotrauma Center in the Neuro Institute at the University of Mississippi Medical Center, and a Physician on the Spinal Cord Injury Medicine and Research Services at the G.V. (Sonny) Montgomery Veterans Administration Medical Center in Jackson Mississippi, USA. After receiving his Bachelor’s and Master’s degrees in biology with a focus on biomechanics from Stanford University in 1985, Tansey earned his Medical and Doctoral (Neuroscience) degrees at the University of Texas Southwestern Medical School in 1994. He then completed his Residency in Neurology at Washington University and Fellowships in Neurorehabilitation and Spinal Cord

Injury Research there and at the University of California at Los Angeles. He was board-certified in Neurology and then earned subspecialty certifications in Spinal Cord Injury Medicine and Neural Repair and Rehabilitation. Dr. Tansey has served on the boards of the American Society for Neurorehabilitation and the International Society for Restorative Neurology (Past-President), and is the current President of the American Spinal Injury Association. He also works on numerous scientific advisory boards and planning groups for other national and international groups. Tansey is an award-winning medical educator and has been invited to speak on his research work internationally. He has had research funding support from NIH, NIDDR/NIDILLR, DoD, VA, Neilsen Foundation, Fox Foundation, and the Mobility Foundation Center. He studies plasticity in neural circuits for pain, autonomic function, locomotion, and upper extremity function in animal models and humans after spinal cord injury, with an interest in shaping that plasticity to improve functional recovery.Education:Mary Washington College (Fredericksburg, VA), BS 1984-1988 Biology Medical College of Virginia (Richmond, VA), MD 1988-1992 Medicine Medical College of Virginia (Richmond, VA) 1992-1996, PM&R University of Colorado Health Sciences Center (Denver, CO) Research Fellowship MSPH 1996-1999, Public Health Craig Hospital (Denver, CO) 1998-1999, Neurorehabilitation FellowshipThis author has the following disclosures:

Other (see below)Member of the International Standards Committee, ASIA President, ASIAStephen Burns, MDSpinal Cord Injury Service, Va Puget Sound Health Care System Bio:Dr. Burns is the director of the Spinal Cord Injury Service at VA Puget Sound Health Care System and an associate professor in the Department of Rehabilitation Medicine at the University of Washington.

He is board certified in physical medicine and rehabilitation and SCI Medicine. He is the former chair of the Neurologic Standards Committee of the American Spinal Injury Association. He is a senior reviewer for the American Board of PM&R SCI Medicine subspecialty certification examination. He serves as medical co-director for the Northwest Regional SCI System of Care, and he directs the VA Advanced Fellowship in SCI Medicine. His research interests include the medical consequences SCI, and neurological assessment and classification techniques. Education:Education History

1984 - 1988 Brown University; Providence, RI Degree: Bachelor of Science in Biology; May 1988

1988 - 1992 Brown Medical School; Providence, RI

Degree: Doctor of Medicine, June 1992

POSTGRADUATE TRAINING 1992 - 1993 Integrated Internship, Department of Rehabilitation Medicine University of Washington; Seattle, WA

1993 - 1994 Residency in Physical Medicine and Rehabilitation, Year 1 University of Washington; Seattle, WA

1994 - 1996 Residency in Physical Medicine and Rehabilitation, Years 2 and 3 Thomas Jefferson University, Philadelphia, PA

1997 - 1998 Participant, Research Enrichment Program for Physiatrists Sponsor: Missouri Arthritis Rehabilitation Research and Training Center and NIDRR; Columbia, MO

Board Certifications

1993 Diplomate, National Board of Medical Examiners

1997 Diplomate, American Board of Physical Medicine and Rehabilitation. Passed Maintenance of Certification Examination in 2005; next due 12/31/17 1999 Subspecialty certification in Spinal Cord Injury Medicine; recertified through 12/31/19.

2000 - 2010 Diplomate, American Board of Electrodiagnostic Medicine This author has the following disclosures:

139Ventilator Weaning Multi-institution Best Practice SymposiumThursday, May 03, 2018 03:45 PM - 04:30 PMLearning Objectives:On completion of this symposium participants will be able to:

1. Discuss recently published studies which may guide pharmacologic strategies for improving ventilator weaning rates. 2. Understand similarities and differences in ventilator weaning practice patterns between two centers with high success rates for ventilator liberation. 3. Review the challenges and opportunities for providing consultation in the acute intensive care (pre-rehabilitation) setting.

Participants:

1McKenna S, 2Crew J, 3Davis M1Santa Clara Valley Medical Center; Stanford University , San Jose , CA, United states; 2Santa Clara Valley Medical Center , San Jose , CA, USA; 3Tirr Memorial Hermann , Houston , Texas, USAStephen McKenna, MDSanta Clara Valley Medical Center; Stanford University Bio:Dr. McKenna is a clinical scientist board certified in Internal Medicine and Neurocritical Care. He is currently the Director of the Rehabilitation Trauma Center at Santa Clara Valley Medical Center (SCVMC). His clinical duties focus on the care of ventilator dependent patients with catastrophic brain and spinal cord injury. His translational research aims to develop evidence based guidelines for the management of brain and spinal cord injury. Dr McKenna’s teaching responsibilities include being the site director for the Advanced Spinal Injury Medicine Fellowship at SCVMC.

In 1995, Dr. McKenna began his clinical career as the Project Manager for the NIH HIV vaccine clinical trial centers in Rwanda and Zambia. Since joining the faculty at SCVMC in 2005, Dr. McKenna has been the principal investigator for numerous clinical trials including investigations of stem cell derived oligodendrocytes for acute spinal cord injury. Dr. McKenna is a founding member of the Stanford Partnership for Spinal Cord Injury and Repair (SPSC). The SPSC leverages scientific and clinical partnerships to reduce the costs - personal, social, and financial - of spinal cord injury. Dr. McKenna holds an appointment at the Stanford University School of Medicine as a Clinical Associate Professor (Affiliated) in the Department of Neurosurgery. In collaboration with Stanford, UCSF and UC Berkley, Dr. McKenna envisages a broad community of practice to translate bench and engineering science to the bedside. Education:6/2002-5/2005 Internal Medicine Resident, Santa Clara Valley Medical Center, San Jose CA 9/1997-5/2002 Stanford University, School of Medicine, Stanford, CA – MD 6/1988-5/1994 University of California, Berkeley, CA – BA Applied Mathematics with Department Honors 6/1988-5/1994 University of California Berkeley, CA – BA Statistics (Epidemiology, Honors Thesis)

This author has no relevant disclosures.James Crew, MDSanta Clara Valley Medical Center Bio:Dr. James Crew has been faculty at Santa Clara Valley Medical Center (SCVMC) for eight years, following his training in PM&R and Spinal Cord Injury (SCI) Medicine at the University of Washington. In 2011, he was appointed the Chief of Spinal Cord Injury at SCVMC. This position includes program oversight of an Inpatient SCI Unit, and collaboration with the Rehab Trauma Center at SCVMC for early SCI management pre-rehabilitation including ventilator management. Dr. Crew is also closely involved with the outpatient clinics at SCVMC to ensure smooth clinical transition and management of patients with SCI across the continuum of care. Additionally, Dr. Crew was appointed Chair of PM&R at SCVMC in 2014, overseeing clinical operations for a moderately large sized inpatient and outpatient academic neurorehabilitation

practice with CARF Accreditation in seven programs. While his clinical work has been focused on treating individuals with SCI in the acute care and inpatient rehabilitation settings, he is also boarded in Neuromuscular Medicine and is actively involved in electrodiagnostics in the inpatient and outpatient setting. His research experience has focused on optimizing function and quality of life after SCI. He has participated as a co-investigator in the Geron OPC1 Stem Cell trial in SCI. He has clinical research experience with biomechanical devices including as the co-PI of a safety and efficacy evaluation of the Ekso wearable exoskeletal device for those with SCI. He currently serves as the SCVMC site Co-PI for the Asterias Stem Cell Clinical Trial in SCI, and was the SCVMC site Co-PI for the Geron Stem Cell Clinical Trial in SCI. Further, he was the SCVMC site PI for the Asubio SUN13837 clinical trial in acute cervical SCI. In addition, he previously received funding through the American Spinal Injury Association Young Investigator Award for his project on the Treatment of Vitamin D Deficiency in Persons with SCI. Dr. Crew is also actively involved in residency training, currently Chair of the Stanford PM&R Research and Quality Committee and having served as site director at SCVMC for the Stanford University PM&R program. He is a member of the Graduate Medical Education Committee at SCVMC, and was recently appointed onto the CNS Council in AAPMR in 2017 as Vice Chair of Education. Dr. Crew is also interested in SCI patient advocacy, having joined the ASIA Health Advocacy Committee in 2017.

Education:Creighton University (Omaha, NE) 1996-2000, Bachelor of Arts, Philosophy, Summa Cum Laude

Creighton University Medical School (Omaha, NE) 2000-2004, Doctorate of Medicine

University of Washington (Seattle, WA) 2004-2005, Transitional Year Internship

University of Washington (Seattle, WA) 2005-2008, Physical Medicine and Rehabilitation Residency

University of Washington/VA Puget Sound Healthcare (Seattle, WA) 2008-2009, Spinal Cord Injury Medicine FellowshipThis author has no relevant disclosures.Matthew Davis, MDTirr Memorial Hermann Bio:Matthew Davis, MD is the clinical medical director of the SCI service line at TIRR Memorial Hermann in Houston, TX. He is an assistant professor in the department of Physical Medicine & Rehabilitation at the McGovern Medical School. He completed his medical school training at Southwestern Medical Center in Dallas, TX, followed by residency training in PM&R in Denver, CO and fellowship in SCI in Seattle, WA. He has a special interest in advocacy for people with SCI and serves as chair of the advocacy committees of two national organizations. Education:UNDERGRADUATE EDUCATION: Washington & Lee University, Lexington, VA Awarded 1998

GRADUATE EDUCATION: Doctor of Medicine, 2003 University of Texas Southwestern Medical Center, Dallas, TX Awarded 2003

POSTGRADUATE TRAINING: Internship 2003-2004 Presbyterian Hospital of Dallas, Department of Internal Medicine Dallas, TX

Residency 2004-2007 University of Colorado Health Sciences Center, Department of Physical Medicine & Rehabilitation Denver, CO

Spinal Cord Injury Fellowship 2007-2008 University of Washington, Department of Rehabilitation Medicine Seattle, WA

This author has no relevant disclosures.

140Expert Panel Discussion of Pathways to Field Testing Clinical Guidelines: Case Study on Ventilator WeaningThursday, May 03, 2018 04:30 PM - 05:15 PMLearning Objectives:On completion of this symposium participants will be able to: • Understand the need for collaboration between clinical consortiums, licensing agencies, and non-governmental organizations in order to promote evidence based algorithms and CPGs for the management of SCI • Discuss the importance and role of consensus-based recommendations in SCI CPGs when there is a paucity of evidence for aspects of management because appropriate research studies have not been published. • Examine the role of CPGs as a teaching tool for both current and future SCI professionals in training and in practice.

Participants:1Parsons K, 2Beattie M, 3Vines C, 1McKenna S, 4Davis M1Paradigm Outcomes Medical Director , Englewood , CO, USA; 2University of California - San Francisco , San Francisco , CA, USA; 3Paralyzed Veterans of America , Washington Dc , Washington, USA; 4Tirr Memorial Hermann , Houston , Texas, USAKenneth Parsons, MDParadigm Outcomes Medical Director

Bio:Kenneth C. Parsons MD is board certified in Physical Medicine and Rehabilitation. He completed his undergraduate education, then completed medical school at the University of Michigan. He completed his residency in Physical Medicine and Rehabilitation at the University of Michigan in 1976. for 30 years of clinical practice he specialized in rehabilitation of persons with spinal cord injury. A longtime member of ASIA, and a past president, Dr. Parsons has organized and presented many educational offerings at ASIA's annual meetings. Dr. Parsons led a multidisciplinary team of healthcare professionals in the development of the Consortium of Spinal Cord Medicine. He served as chairperson of the Steering Committee for the Consortium from 1994 to 2004. With the support of Paralyzed Veterans of America, the Consortium has published many clinical practice guidelines to improve the clinical management after spinal cord injury. Dr. Parsons was the lead author of the CPG entitled Respiratory Management Following Spinal Cord Injury. Dr. Parsons has had academic affiliations with several departments of Physical Medicine and Rehabilitation. He currently serves as a Paradigm Medical Director for Paradigm Outcomes, and assists in the Outcome focused care of catastrophically injured workers with spinal cord injury. Dr. Parsons lives in Englewood, Colorado with his wife, Carolyn. He has three children and two grand children.

Education:1. Undergraduate: University of Michigan (3 years pre-med, 1963-1966)

2. Graduate: University of Michigan Medical School (1966-1970) Graduated: June 6, 1970

3. Internship: St. Joseph’s Mercy Hospital Ann Arbor, Michigan 48106 July 1, 1970 – June 30, 1971

4. Residency: University Hospital Ann Arbor, Michigan Department of Physical Medicine and Rehabilitation July 1, 1971 to August 31, 1971 Sep 1, 1973 to June 30, 1976

This author has no relevant disclosures.Michael Beattie, Ph.DUniversity of California - San Francisco Bio:

Dr. Beattie received his Ph.D. from The Ohio State University in 1977, where he stayed on to become the founding chair of the Department of Neuroscience in 1999. He and his wife and colleague, Jacqueline Bresnahan, joined the University of California, San Francisco in 2006. He is currently Co-Director and Director of Research for the Brain and Spinal Injury Center

(BASIC) in the Weill Institute for Neurosciences and Department of Neurological Surgery at UCSF. His interests are in the cell biology of CNS injury and repair, and preclinical and clinical neurotrauma research. He has authored more than 140 peer-reviewed publications and has served on multiple editorial and NIH and other review panels. He is a member of the Boards of Directors of the American Spinal Injury Association (ASIA) and the Rick Hansen Foundation, and a member of the NIH CNNT study section. He and Dr. Bresnahan are the recipients of the 2012 Reeve-Irvine Research medal for excellence in spinal cord injury research.Education:1967 - 1972 University of California, Davis B.S. Biological Psychology

1972 - 1974 Ohio State University M.A. Neuropsychology

1974 - 1977 Ohio State University Ph.D. Neuropsychology/Neuroanatomy

1977 - 1978 Ohio State University NIH Postdoctoral fellow Neuroanatomy

1978 - 1979 Michigan State University Postdoctoral NeurophysiologyThis author has no relevant disclosures.Cheryl Vines, MSParalyzed Veterans of America Bio:Cheryl Lady Vines is the Director of Research and Education at Paralyzed Veterans of America, a consumer driven organization advocating for access to quality health care, access to benefits, access to the community and research to improve the lives of veterans and others living with spinal cord injury. There she manages the grant portfolios for the PVA Research Foundation and Education Foundation as well as coordinating the development and dissemination of the SCI Clinical Practice Guidelines.

Ms. Vines was previously the Executive Director of the Arkansas Spinal Cord Commission, a state agency that identifies and provides a wide array of services to Arkansans who have sustained spinal cord disabilities. As part of this model system of community-based care Ms. Vines managed the legislatively mandated, population based, Arkansas Spinal Cord Disability Registry and a lifelong follow up and case management program for Arkansans living with spinal cord disabilities. She has done extensive research developing community-based models to identify and prevent secondary conditions in people with spinal cord disabilities. This included the Consumer Action

to Prevent Pressure Sores (CAPPS) project in collaboration with the Centers for Disease Control and Prevention Disability and Wellness program.

Ms. Vines began her career as a Recreation Therapist and is a strong proponent of recreation and leisure education for people with spinal cord disabilities and has been involved in the wheelchair sports movement on the local, national and international levels. In addition to her membership in ASIA she is a member of ASCIP and the National Spinal Cord Injury Association. She serves on the Boards of Directors the PVA Education Foundation, Arkansas Spinal Cord Foundation and Be Extraordinary.

Ms. Vines holds a Bachelors Degree from California State University, Fresno and a Masters Degree from The Florida State University.Education:Florida State University, Tallahassee, Florida,1980. Master of Science, Human Services and Studies/Leisure Services and Studies,

California State University, Fresno, 1976 Bachelor of Science, Recreation Administration This author has no relevant disclosures.Stephen McKenna, Paradigm Outcomes Medical Director Bio:Dr. McKenna is a clinical scientist board certified in Internal Medicine and Neurocritical Care. He is currently the Director of the Rehabilitation Trauma Center at Santa Clara Valley Medical Center (SCVMC). His clinical duties focus on the care of ventilator dependent patients with catastrophic brain and spinal cord injury. His translational research aims to develop evidence based guidelines for the management of brain and spinal cord injury. Dr McKenna’s teaching responsibilities include being the site director for the Advanced Spinal Injury Medicine Fellowship at SCVMC.

In 1995, Dr. McKenna began his clinical career as the Project Manager for the NIH HIV vaccine clinical trial centers in Rwanda and Zambia. Since joining the faculty at SCVMC in 2005, Dr. McKenna has been the principal investigator for numerous clinical trials including investigations of stem cell derived oligodendrocytes for acute spinal cord injury. Dr. McKenna is a founding member of the Stanford Partnership for Spinal Cord Injury and Repair (SPSC). The SPSC leverages scientific and clinical partnerships to reduce the costs - personal, social, and financial - of spinal cord injury. Dr. McKenna holds an appointment at the Stanford University School of Medicine as a Clinical Associate Professor (Affiliated) in the Department of Neurosurgery. In collaboration with Stanford, UCSF and UC Berkley, Dr. McKenna envisages a broad community of practice to translate bench and engineering science to the bedside.

Education:6/2002-5/2005: Internal Medicine Resident, Santa Clara Valley Medical Center, San Jose CA

9/1997-5/2002: Stanford University, School of Medicine, Stanford, CA – MD

6/1988-5/1994: University of California, Berkeley, CA – BA Applied Mathematics with Department Honors

6/1988-5/1994 University of California Berkeley, CA – BA Statistics (Epidemiology, Honors Thesis) This author has no relevant disclosures.Matthew Davis, MDTirr Memorial Hermann Bio:Matthew Davis, MD is the clinical medical director of the SCI service line at TIRR Memorial Hermann in Houston, TX. He is an assistant professor in the department of Physical Medicine & Rehabilitation at the McGovern Medical School. He completed his medical school training at Southwestern Medical Center in Dallas, TX, followed by residency training in PM&R in Denver, CO and fellowship in SCI in Seattle, WA. He has a special interest in advocacy for people with SCI and serves as chair of the advocacy committees of two national organizations. Education:

UNDERGRADUATE EDUCATION: Washington & Lee University, Lexington, VA Awarded 1998

GRADUATE EDUCATION: Doctor of Medicine, 2003 University of Texas Southwestern Medical Center, Dallas, TX Awarded 2003

POSTGRADUATE TRAINING:

Internship 2003-2004 Presbyterian Hospital of Dallas, Department of Internal Medicine Dallas, TX

Residency 2004-2007 University of Colorado Health Sciences Center, Department of Physical Medicine & Rehabilitation Denver, CO

Spinal Cord Injury Fellowship 2007-2008

University of Washington, Department of Rehabilitation Medicine Seattle, WA This author has no relevant disclosures.

141Ouch… that hurts!! Understanding, assessing, and treating pain in youth with spinal cord injury using a multidisciplinary approachThursday, May 03, 2018 03:45 PM - 04:45 PMLearning Objectives:1. To identify the frequency of pain in children with SCI.

2. To be familiar with developmentally appropriate assessments of pain in youth with SCI.

3. To understand, from an interdisciplinary perspective, various forms of treatment for youth with SCI.

Participants:Russell H, Scharff K, Pittman M, Lipa BShriners Hospitals for Children- Philadelphia , Philadelphia , PA, USAHeather Russell, PhDShriners Hospitals for Children- Philadelphia Bio:I have had extensive training and experience in both the clinical and research realms within the field of pediatric psychology. In an effort to disseminate my research findings, I have published over 25 articles in peer reviewed journals and presented over 50 times at national meetings on this topic. Specifically, my expertise is in working with children with physical disabilities or chronic conditions and their families in order to better understand and facilitate the coping and adjustment processes with the ultimate goal of optimizing psychosocial outcomes. I also have extensive involvement in the professional realm where I serve as the President of the Psychology, Social Work and Counseling section of the Academy of Spinal Cord Injury Professionals (PSWC/ASCIP), in addition to serving as the Vice-President of the Governance Board (GB/ASICP), and as a long-term member of the PSWC Clinical Practice Committee. In the American Spinal Injury Association, I serve as a member of the Program Committee (Past Chair 2015-2017) and as a member of the Pediatric Committee. Lastly, I was honored to be named the 2014 recipient of the Clinical Practice Award for PSWC/ASCIP and to receive a Leadership Service Award in 2017 from ASIA. All of these clinical, research and professional experiences have come together to make me a well-rounded professional.Education:Smith College, Northampton, MA AB 5/1991 Biology

La Salle University, Philadelphia, PA MA 5/1995 Psychology

duPont Hospital for Children, DE Intern 1997-1998

Temple University, Philadelphia, PA PhD 2000 Psychology

Children’s Hospital of Philadelphia, PA Fellow 2000-2001

This author has no relevant disclosures.Kim Scharff, PT, DPT, PCSShriners Hospitals for Children- Philadelphia Bio:Kimberly A. Scharff, PT, DPT, PCS is a physical therapist at Shriners Hospitals for Children – Philadelphia. She received a Bachelor of Science degree in Biology from Villanova University, a Master of Education degree from Cabrini College, and a Doctorate of Physical Therapy degree from Drexel University in 2006. She is a Pediatric Clinical Specialist as designated by the American Physical Therapy Association. She has ten years of experience evaluating and treating children and youth with spinal cord injuries. She is the current co-chair of the ASIA Pediatrics Committee. Education:Drexel University, Philadelphia, PA Doctorate of Physical Therapy, May 2006

Cabrini College, Radnor, PA Master of Education, August 2000

Villanova University, Villanova, PA Bachelor of Science in Biology, May 1996 This author has no relevant disclosures.Madeleine Pittman, MS, OTR/L, CKTPShriners Hospitals for Children- Philadelphia Bio:Madeleine Pittman, MS, OTR/L, CKTP is an occupational therapist at Shriners Hospitals for Children in Philadelphia. She received a Bachelors of Science in Exercise Physiology and a Masters of Science in Recreation, Parks and Tourism from West Virginia University, and a Masters of Science in Occupational Therapy from Philadelphia University in 2013. She is a Certified Kinesio Tape Practitioner and has three years experience evaluating and treating children with spinal cord injuries. Education:Philadelphia University, Philadelphia, PA Masters of Science in Occupational Therapy, May 2013

West Virginia University, Morgantown, WV Masters of Science in Recreation, Parks and Tourism Resources, May 2010

West Virginia University, Morgantown, WV Bachelor of Science in Exercise Physiology, May 2008 This author has no relevant disclosures.

Bethany Lipa, MDShriners Hospitals for Children- Philadelphia Bio:I have cared for children and young adults with mobility impairment and physical limitations associated with neuromuscular conditions for the past six years. My clinical focus has been on improving mobility, participation and quality of life while minimizing medical complications caused by complex neuromuscular disorders. My clinical research interest include predicting neuro recovery through early electrodiagnostic screening after brachial plexus birth palsy, improving mobility and trunk strength through activity based rehabilitation after spinal cord injury, and improving individualized goal attainment by treating lower limb spasticity with botulinum toxin injections. I also have a passion for caring for children and youth with spinal cord injury. At Shriners Hospitals for Children Philadelphia, I work regularly with children and youth up to 21 years of age on our inpatient rehabilitation unit and outpatient clinics. I have seen first-hand the critical importance of treating pain with a multidisciplinary team approach to improve outcomes, participation and avoid long-term complications. Education:State University of New York, Geneseo NY BS 05/2003

University of Buffalo, Buffalo NY MD 05/2007

UMDNJ/Rutgers University, Newark NJ Internship 06/2008

UMDNJ/Rutgers University, Newark NJ Residency 06/2011

UC Davis Medical Center, Sacramento CA Shriners Hospitals for Children, Northern California Fellowship 07/2012

UC Davis Medical Center, Sacramento, CA Fellowship 08/2013 This author has no relevant disclosures.

142Yoga: A Holistic Approach to Treating Multidimensional Pain After Spinal Cord Injury/Disorder (SCI/D)Thursday, May 03, 2018 04:45 PM - 05:15 PMLearning Objectives:1. Describe the physiological impacts of breathing (pranayama) on the pain response. 2. List the physiological benefits of postures (asana) for each pain syndrome experienced by individuals with SCI/D. 3. List the impact of mindfulness/ meditation on body awareness for managing pain in individuals with SCI/D.

Participants:

McNair K, Baig KKessler Institute for Rehabilitation , West Orange , NJ, 07052Keara McNair, MS, OTR/L, BCPR, RYTKessler Institute for Rehabilitation Bio:Keara McNair began her career at Medstar National Rehabilitation Hospital on general medicine, pediatric, and spinal cord injury units. She developed her practice further into a focus of working with patients with motor complete spinal cord injuries, particularly C4-C6 tetraplegia, including use of environmental controls, advanced home modifications, and durable medical equipment for this population. She began working at Kessler West Orange in 2014 after completing a month long 200- hour yoga teacher training at the Integral Yoga Institute in Buckingham, Virginia. At Kessler, she was additionally trained in ventilator care. She has been responsible for running the Arm Hand Program to address upper extremity management of patients with incomplete tetraplegia and presented on her success with the program at the Annual ASIA Scientific Meeting in April 2016. She is the co- lead of Kessler’s EADL program and presented at the ASCIP conference in 2017 on integrating consumer- based technology into an EADL program.Education:University at Buffalo, The State University of New York. Masters in Occupational Therapy (June 2011).

University at Buffalo, The State University of New York. Bachelors in Occupational Science (June 2011).This author has the following disclosures:

Other (see below)Salaried employee of Kessler Institute for Rehabilitation, West Orange, NJ.Karyn Baig, PT, DPT, RYTKessler Institute for Rehabilitation Bio:Karyn Baig, PT, DPT, RYT is a physical therapy clinical specialist in outpatient spinal cord injury at Kessler Institute for Rehabilitation in West Orange, NJ with over nine years of experience working with the SCI/D population. She began her career at Kessler Rehabilitation in 2008 and worked for over eight years in inpatient spinal cord injury before transitioning to outpatient in order to further pursue her passion for community reintegration and embracing the potential that exists beyond the rehabilitation setting, including peer support, adapted recreation, and yoga. She completed her yoga teacher training in 2015 with the Marianne Wells Yoga School in Costa Rica in order to provide a more holistic, comprehensive approach to patient care. She has presented at the annual ASIA meeting and ASCIP conference on integrating yoga into a plan of care for individuals with spinal cord injury. She has played an integral role in developing Kessler's peer program and participates in multiple community activities for SCI advocacy.Education:5/2008 Columbia University, College of Physicians and Surgeons, New York City, NY Doctor of Physical Therapy 9/2003- Orange Coast College, Costa Mesa, CA 5/2005 Physical Therapy Prerequisites

5/1998 Cornell University, Ithaca, NY Bachelor of Science in Communication, Concentration in Business Management Dean’s ListThis author has the following disclosures:

Other (see below)Salaried employee of Kessler Institute for Rehabilitation, West Orange, NJ.

143Increasing the clinical value of the zones of partial preservation – A quantitative comparison of a new definition rule applicable also in incomplete lesionsFriday, May 04, 2018 09:15 AM - 10:15 AMLearning Objectives:Participants will be able to recognize a limitation of the current zone of partial preservation (ZPP) defined in ISNCSCI and will learn the benefit of a slightly changed ZPP rule.

Participants:1Schuld C, 1Franz S, 1Weidner N, 2Kirshblum S, 3Tansey K, 1Rupp R1Heidelberg University Hospital , Heidelberg , , Germany; 2Kessler Institute for Rehabilitation , West Orange , New jersey, USA; 3Methodist Rehabilitation Center , Jackson , Mississipp, USAChristian Schuld, Dipl.-Inform. Med.Heidelberg University Hospital Bio:BIOGRAPHICAL SKETCH

NAME OF APPLICANT: Christian Schuld POSITION TITLE: Research Associate

INSTITUTION AND LOCATION DEGREE START END FIELD OF STUDY Hoechst AG Apprenticeship 09/95 07/97 IT specialist University Heidelberg, Germany Diploma (M.Sc.) 10/98 03/05 Medical Informatics

PERSONAL STATEMENT My long term research interests involve human gait analysis with focus on gait deviations resulting from spinal cord injury (SCI). Beyond analysis, I am also interested in gait therapy and restoration using novel approaches like putting the patient in loop and provide real-time feedback from the running gait analysis. In order to be able to validly and reliably measure the benefits, clinical outcome measured are of utmost importance. In the field of SCI medicine, the International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI) stands out as “the” internationally accepted tool to quantify the location and severity of a SCI. Starting as the database developer of the European Multicenter Study about Spinal Cord Injury (EMSCI) I have become involved in ISNCSCI research resulting in multiple publications on ISNCSCI training, the ISNCSCI calculators and studies simulating the effects of possible revisions using modified calculators and large datasets.

Education:ACTIVITY START END FIELD COMPANY SUPERVISOR IT specialist 07/97 06/98 IT support Celanese GmbH Thomas Huschke

Research associate 05/05 12/09 rehabilitation engineering Stiftung Orthopädische Universitätsklinik Rüdiger Rupp

Research associate 01/10 present rehabilitation engineering Heidelberg University Hospital, Spinal Cord Injury Center

OTHER EXPERIENCES AND PROFESSIONAL MEMBERSHIPS 2013- American Spinal Injury Association (ASIA) 2011- International Spinal Cord Society (ISCos)This author has the following disclosures:

Other (see below)Christian Schuld is member of the International Standards Committee.Steffen Franz, MDHeidelberg University Hospital This author has the following disclosures:

Other (see below)Steffen Franz is member of the Educational Committee.Norbert Weidner, MDHeidelberg University Hospital This author has no relevant disclosures.Steven Kirshblum, MDKessler Institute for Rehabilitation This author has the following disclosures:

Other (see below)Steven Kirshblum is board liaison in the International Standards Committee and member of the Educational Committee.Keith Tansey, MD, PhDMethodist Rehabilitation Center This author has the following disclosures:

Other (see below)Keith Tansey is president of the American Spinal Injury Association and member of the International Standards Committee.Rüdiger Rupp, PhDHeidelberg University Hospital This author has the following disclosures:

Research Support Other (see below)

Rüdiger Rupp is chair or the International Standards Committee. Rüdiger Rupp received funding from:

The European Multicenter Study about Spinal Cord Injury (EMSCI) and Deutsche Stiftung Querschnittlähmung (DSQ).

144Validity and Reliability of Physical Abilities and Mobility Scale (PAMS) in children with spinal cord related paralysis Friday, May 04, 2018 09:15 AM - 10:15 AMLearning Objectives:Become familiar with Physical Abilities and Mobility Scale

Participants:Sadowsky C, Neuland EKennedy Krieger Institute , Baltimore , MD, USACristina Sadowsky, MDKennedy Krieger Institute Bio:Dr. Sadowsky is Clinical Director of the International Center for Spinal Cord Injury at Kennedy Krieger Institute in Baltimore, a program caring for both children and adults with spinal cord related paralysis and built on the philosophy that functional restoration is activity dependent and can be best achieved through structured medico-rehabilitative interventions. Dr. Sadowsky’s research interests’ center on prevention of complications in patients with paralysis and the efficacy of activity based restorative therapies (ABRT) in helping individuals with long-term spinal cord injury and paralysis recover sensation, movement and independence. She has published in highly regarded specialty related peer reviewed journals, wrote chapters in seminal specialty books, has organized numerous courses and seminars, and has been invited to lecture in different universities, and at national and international meetings.Education:9/83-9/89 MD degree, Institute of Medicine and Pharmacy, Bucharest, Romania 7/91-6/95 Internal Medicine Internship and Residency, Meridia Huron-Hillcrest Hospital, Cleveland, Ohio Lawrence Gray, MD, Primary Mentor 7/95-6/98 Physical Medicine and Rehabilitation Residency, Barnes-Jewish Hospital, Washington University School of Medicine, St. Louis, Missouri Oksana Volshteyn, MD, Primary Mentor 7/98 -6/99 Spinal Cord Injury Medicine Fellowship, Barnes-Jewish Hospital, Washington University School of Medicine, St. Louis, Missouri Oksana Volshteyn, MD, Primary Mentor

This author has no relevant disclosures.Erin Neuland, DPTKennedy Krieger Institute This author has no relevant disclosures.

145Psychometric Properties of the Spinal Cord Independence Measure-III Self Report- YouthFriday, May 04, 2018 09:15 AM - 10:15 AMLearning Objectives:Participants will be able to discuss psychometric properties of the SCIM-III SR-Y

Participants:1Mulcahey M, 1Thielen C, 2Sadowsky C, 2Martin R, 3Vogel L, 4Taylor H, 5Davidson L1Thomas Jefferson University , Philadelphia , PA, United states; 2Kennedy Krieger Institute , Baltimore , MD, USA; 3Shriners Hospitals for Children , Chicago , IL, United states; 4Tirr Herman Memorial , Houston , Texas, USA; 5Shriners Hospitals for Children Northern Ca , Sacramento , CA, USAMJ Mulcahey, PhD, OTR\LThomas Jefferson University Bio:Dr. Mulcahey is Professor and Director of Research in the Dept. of Occupational Therapy, College of Health Professions at Thomas Jefferson University, Philadelphia. Dr. Mulcahey previously served as Director of Rehabilitation and Research at the Shriners Hospitals for Children Philadelphia, where she remains active on Scientific Staff. Much of Dr. Mulcahey's research has focused on development, validation and dissemination of clinically relevant outcome instruments for pediatric spinal cord injury. She led a seminal study that established the psychometric properties of the ISNCSCI motor, sensory and anorectal examinations in children, and used the study results to develop guidelines for use of the ISNCSCI in children and youth. These guidelines form the basis for ASIA's elearning module "WeeStep." She has also developed and validated computerized adaptive tests and short forms of activity and participation for child and parent report, and worked collaboratively with investigators at Boston University to link them to the adult SCI-FI to create a measure that can be administered across the life span. She is currently funded to carry-out a knowledge translation project to facilitate uptake of these measures by practitioners and researchers. Dr. Mulcahey has served the SCI field in multiple capacities. She is immediate past president of ASIA and serves on several ASIA committees, and has acted as chair for or participated as a member in review panels for NIDILRR, Dept. of Defense, Craig H. Neilsen Foundation, Wings for Life, AOTF and Action Research. She is on the editorial board of Spinal Cord, J Physical Therapy, American J Occupational Therapy, Physical and Occupational Therapy in Pediatrics, and is Associate Editor of Topics in SCI Rehabilitation. Her research has\is funded by Shriners Hospitals for Children, NIH, Craig H. Neilsen Foundation and, Rick Hansen Institute. Education:Gwynedd Mercy College (BS Special and Elementary Education) Thomas Jefferson University (post-BS and MS Occupational Therapy) Capella University (PhD Education) Boston University (Visiting Scientist, Measurement)This author has the following disclosures:

Research Support

Other (see below)Receives research funding from Shriners Hospitals for Children, Craig H. Neilsen Foundation, NIH, Rick Hansen Institute. Receives compensation for associate editor of Topics in SCI Rehab.

Member of the ASIA BOD, Vice President Pediatric Spine Foundation, Chair Steel Assembly Christina Thielen, Thomas Jefferson University This author has no relevant disclosures.Cristina Sadowsky, MDKennedy Krieger Institute This author has no relevant disclosures.Rebecca Martin, OTDKennedy Krieger Institute This author has no relevant disclosures.Lawrence Vogel, Shriners Hospitals for Children This author has the following disclosures:

Other (see below)Receives compensation for Editor of Topics in SCI Rehab

BOD Steel AssemblyHeather Taylor, PhDTirr Herman Memorial This author has no relevant disclosures.Loren Davidson, MDShriners Hospitals for Children Northern Ca This author has no relevant disclosures.

146GRASSP Version 2: A comprehensive SCI upper limb outcome measureFriday, May 04, 2018 09:15 AM - 10:15 AMLearning Objectives:1. To enhance understanding of the modifications made to GRASSP, and the applications of these changes.

Participants:1Kalsi-Ryan S, 2Albisser U, 3Fehlings M, 2Curt A, 4Verrier M, 5Fellinghauer C, 6Velstra I1Toronto Rehabilitation Institute - Uhn , Toronto , Ontario, Canada; 2University Hospital, Balgrist , Zurich , , Switzerland; 3Toronto Western Hospital - Uhn , Toronto , , Canada; 4University of Toronto , Toronto , Ontario, Canada; 5Swiss Paraplegic Research, Icf Unit; University Lucerne, Department of Health Science and Health Policy , Lucerne , , Switzerland; 6Swiss Paraplegic Centre Nottwil, Clinical Trial Unit , Nottwil , , Switzerland

Sukhvinder Kalsi-Ryan, BScPT, MSc, PhDToronto Rehabilitation Institute - Uhn Bio:Dr. Kalsi-Ryan, is a Clinician Scientist in the field of upper limb assessment and recovery and spine pathology at TRI-UHN and is also Assistant Professor at the University of Toronto, Department of Physical Therapy. Her research is oriented to establishing methods to quantify neurological change after injury and studying neuro-restorative methods to enhance and optimize function for those with neurological impairment. After gaining her Bachelors of Science, Dr. Kalsi-Ryan, focused on brain injury and stroke patients as a Physiotherapist at St. Michael’s Hospital. From there, she began a 19-year tenure at the Toronto Western Hospital (TWH), joining the staff initially as a frontline Physical Therapist in 1997 and then a Research Physical Therapist in 2006. Dr. Kalsi-Ryan completed a Post Doctoral Fellowship at TWH’s Krembil Neuroscience Centre in 2015, focusing on clinical research with the traumatic and non-traumatic SCI population and transferring her skillset in development of sensitive outcomes to other neurological disorders.

Kalsi-Ryan continues as a clinical researcher and continues work on several research committees and collaborations. Her research is oriented to establishing methods to quantify neurological change after injury and understand neuro-restorative methods to enhance and optimize function for those with neurological impairment. She has participated on the International Acute SCI Clinical Practice Guidelines Committee, which were recently published in the Global Spine Journal. Since completing her Master’s degree, Kalsi-Ryan has been awarded over $1.6 million in research grants in both the Primary and Co-Investigator roles, from foundations such as the CIHR, Craig Neilsen Foundation, AO Spine North America, and the Physical Therapy Foundation of Canada.

She is the Founder of her own company that manufactures the GRASSP; she acts as a consultant for neurological trials worldwide and has recently co-founded the Spine Therapy Network. Education:Post Doctor Fellowship, Krembil Neuroscience Centre (2010-2015) PhD, University of Toronto, Rehab Sciences Institute (2006-2011) MSc, University of Toronto, Rehab Sciences Institute (2000-2005) BScPT, University of Toronto, Dept of Physical Therapy (1991-1995)This author has the following disclosures:

ConsultantNeural Outcomes, manufacturer of GRASSP, consulting or outcomes to pharmaceutical industryUrs Albisser, BScOTUniversity Hospital, Balgrist This author has no relevant disclosures.Michael Fehlings, MD, PhDToronto Western Hospital - Uhn This author has no relevant disclosures.Armin Curt, MDUniversity Hospital, Balgrist This author has no relevant disclosures.

Molly Verrier, DipPT, MHScUniversity of Toronto This author has no relevant disclosures.Carolina Fellinghauer, PhDSwiss Paraplegic Research, Icf Unit; University Lucerne, Department of Health Science and Health Policy This author has no relevant disclosures.Inge-Marie Velstra, BScOT, PhDSwiss Paraplegic Centre Nottwil, Clinical Trial Unit This author has no relevant disclosures.

147Development of the International SCI Basic Data Set for Caregivers: Capturing data beyond the person with SCI/DFriday, May 04, 2018 09:15 AM - 10:15 AMLearning Objectives:At the conclusion of this presentation, participants will understand the rationale for development of a caregiver basic data set and describe the iterative process used for development and validation.

Participants:1Haywood C, 2Martin R, 3Mulcahey M, 4Pediatric I1University of Southern California , Los Angeles , CA, 90089; 2Kennedy Krieger Institute , Baltimore , MD, USA; 3Thomas Jefferson University , Philadelphia , PA, USA; 4Multiple Institutions Represented , Multiple Cities Represented , , InternationalCarol Haywood, OTR/LUniversity of Southern California Bio:Carol Haywood, OTR/L, is a PhD Candidate in Occupational Science at the University of Southern California. She received her Bachelor’s degree in Psychology and Master’s degree in Occupational Therapy from St. Ambrose University in Davenport, Iowa. From 2009-2013, she worked in inpatient care at the Rehabilitation Institute of Chicago with a focus in pediatric rehabilitation. Now at the University of Southern California in Los Angeles, California, Carol is completing dissertation research to better understand experiences of participation and development for adolescents and young adults with spinal cord injuries and their caregivers by employing narrative and phenomenological research methods. Carol has also received funding from the Patient-Centered Outcomes Research Institute (PCORI) Pipeline-to-Proposal Award program to collaborate with adolescents and young adults with chronic health conditions and other community stakeholders for research development, implementation, and dissemination.Education:University of Southern California (Los Angeles, CA), PhD Occupational Science, In Progress

St. Ambrose University (Davenport, IA), MA Occupational Therapy, 2009

St. Ambrose University (Davenport, IA), BA Psychology, 2008 This author has no relevant disclosures.Rebecca Martin, OTR/L, OTD, CPAMKennedy Krieger Institute Bio:Dr. Martin received her Bachelors of Science in Occupational Therapy from Boston University in 2001 and her Occupational Therapy Doctorate from Rocky Mountain University of Allied Health Professions in 2008. Prior to joining the Kennedy Krieger Institute, Dr. Martin worked in brain injury rehabilitation in Boston, Massachusetts.

Dr. Martin joined Kennedy Krieger in 2005 as a Senior Occupational Therapist in the International Center for Spinal Cord Injury. Since 2010, Dr. Martin has been the Manager of Clinical Education and Training at ICSCI and is responsible for program development, staff training, and oversight of the clinical research program. Dr. Martin speaks nationally on topics related to Activity-Based Rehabilitation; she has taught many continuing education courses for rehabilitation professionals in the areas of neurological pathology, rehabilitation, and research. She has been the principal investigator and co-investigator for grants from the Paralyzed Veterans of America Education Foundation and Department of Defense to develop, promote, and disseminate an activity-based restorative therapy training program and curriculum.Education:Sargent College of Allied Health and Rehabilitation Sciences at Boston University (Boston, MA), BS Occupational Therapy, 2001

Rocky Mountain University of Allied Health Professions (Provo, UT), Occupational Therapy Doctorate, 2008 This author has no relevant disclosures.Mary Jane Mulcahey, PhD, OTR/LThomas Jefferson University This author has no relevant disclosures.International Spinal Cord Injury Basic Data Set Caregiver Workgroup Pediatric, Multiple Institutions Represented This author has no relevant disclosures.

148Item Banks for Measuring the Impact of Blood Pressure Dysregulation on Health-Related Quality of Life in Persons with Spinal Cord InjuryFriday, May 04, 2018 09:15 AM - 10:15 AMLearning Objectives:To present a qualitative assessment tool for clinical evaluation of the impact of blood pressure dysregulation in persons with SCI on health-related quality of life and everyday activities.

Participants:

1Wecht J, 2Morin K, 3Kallen M1Dr. , Bronx , Ny - new y, USA; 2James J Peters Va Medical Center , Bronx , NY, USA; 3Epartment of Medical Social Sciences, Northwestern University Feinberg School of Medicine , Chicago , IL, USAJill Wecht, Dr. Bio:I have been investigating the impact of Spinal Cord Injury (SCI) on autonomic regulation of the cardiovascular system and have published numerous articles describing the effects of orthostatic positioning on blood pressure regulation and cerebral blood flow. I am presently the PI of the Cardiovascular/Autonomic Program within the National Center for the Medical Consequences of SCI, and the focus of this investigative body of work is to develop a battery of clinical tests to determine the integrity of autonomic cardiovascular regulation in individuals with SCI. It is anticipated that this battery of tests will be easy to use and will provide the clinician with valuable information to help guide treatment algorithms for cardiovascular health and longevity in the SCI population. Although hypotension is a common cardiovascular finding in the SCI population, particularly in individuals with lesions above thoracic level 6, my laboratory has noted that many hypotensive individuals with SCI remain asymptomatic and do not complain of symptoms associated with cerebral hypoperfusion, which include dizziness, lightheadedness, nausea, blurred vision, ringing in the ears, and fatigue. However, after administration of an anti-hypotensive medication these individuals with SCI feel better and report more energy, improved motivation and a general feeling of warmth. Education:1999 Doctorate of Education: Applied Physiology Teachers College, Columbia University, New York, NY 1989 Master of Science: Applied Physiology Springfield College, Springfield, MA 1987 Bachelor of Science: Health Sciences Lock Haven University, Lock Haven, PA This author has no relevant disclosures.Kel Morin, BSJames J Peters Va Medical Center This author has no relevant disclosures.Michael Kallen, PhD, MPHEpartment of Medical Social Sciences, Northwestern University Feinberg School of Medicine This author has no relevant disclosures.

149Recovery after thoracic and lumbar traumatic spinal cord injury: the neurological level of lesion mattersFriday, May 04, 2018 09:15 AM - 10:15 AMLearning Objectives:Discuss the differences in functional outcomes between TSCI, CMS and CES.

Participants:Brouwers ERadboud University Medical Center , Nijmegen , Gelderland, The netherlandsEveline Brouwers, MPA, PhD studentRadboud University Medical Center Bio:Eveline Brouwers is physician Assistant, department of neurosurgery at the Radboud University Medical Center in Nijmegen, the Netherlands. Besides her ward activities, she is a PhD student. Topic: traumatic spinal cord injuries with special interest in the Conus Medullaris and Cauda Equina.Education:Physiotherapy, Hogeschool Arnhem - Nijmegen (BS) 2003 - 2007

Physician Assistant, Hogeschool Arnhem en Nijmegen (MPA) 2010 - 2013

PhD student Radboud University Nijmegen, from 2016 This author has no relevant disclosures.

150The Effects of Acute Aerobic Exercise on Inflammatory Markers and Mood in Individuals with Multiple Sclerosis and Spinal Cord InjuryFriday, May 04, 2018 09:15 AM - 10:15 AMLearning Objectives:To understand the role of acute exercise in improving mood in individuals with spinal cord injury and multiple sclerosis, and to understand the role of exercise-induced changes in pro-inflammatory cytokines in the exercise-induced improvements in mood.

Participants:1Donia S, 2Allison D, 1Gammage K, 1Ditor D1Brock University , St. Catharines , Ontario, Canada; 2Mcmaster University , Hamilton , Ontario, CanadaScott Donia, MScBrock University Bio:Scott A. Donia, MSc, is a Research Assistant in the Neuromuscular Acquisition & Rehabilitation Lab at Brock University under the supervision of Dr. David Ditor, and Head Trainer at Power Cord, an adaptive exercise facility for people with spinal cord injuries, multiple sclerosis, and lower limb amputations under the umbrella of the Brock-Niagara Centre for Health and Well-Being where he is also a part-time supervisor. His research focuses on acute aerobic exercise and its role in the improvement of mood in individuals with SCI & MS via inflammatory mechanisms.

Education:Brock University (St. Catharines, ON) BSc 2010-2014 Kinesiology Brock University (St. Catharines, ON) MSc 2015-2017 Kinesiology This author has no relevant disclosures.David Allison, PhDMcmaster University This author has no relevant disclosures.Kimberley Gammage, PhDBrock University This author has no relevant disclosures.David Ditor, PhDBrock University This author has no relevant disclosures.

151Does the functional outcome 6 months after a traumatic spinal cord injury predicts the chronic functional outcome 12 months after the injury?Friday, May 04, 2018 09:15 AM - 10:15 AMLearning Objectives:Discuss the factors associated with a clinically important improvement in functional outcome between 6 and 12 months after a traumatic spinal cord injury (TSCI)

Participants:1Chatta R, 2Thompson C, 2Richard-Denis A, 2Mac-Thiong J1Faculty of Medicine, University of Montreal , Montreal , Quebec, Canada; 2Hôpital Du Sacré-Coeur , Montreal , Quebec, CanadaRami Chatta, BScFaculty of Medicine, University of Montreal This author has the following disclosures:Cynthia Thompson, PhDHôpital Du Sacré-Coeur This author has the following disclosures:Andréane Richard-Denis, MDHôpital Du Sacré-Coeur This author has the following disclosures:Jean-Marc Mac-Thiong, MD, PhDHôpital Du Sacré-Coeur Bio:Jean-Marc Mac-Thiong, MD, PhD, is a clinician-scientist practicing as an orthopedic spine surgeon at the Hopital du Sacre-Coeur de Montreal, with a multidisciplinary background in spine surgery (MD, fellowship), biomedical sciences (MSc, PhD), and engineering (BEng). He is an associate professor of surgery and research director of the Orthopedics Division at Université de

Montréal. He is Chairman of the Medtronic Research Chair in spinal trauma at Université de Montréal and in charge of the Rick Hansen Spinal Cord Injury Registry at Hopital du Sacre-Coeur de Montreal. He is Chair of the Spine/Acute care Committee at the American Spinal Injury Association. His research has been supported by the Canadian Funds for Innovation, Natural Sciences and Engineering Research Council of Canada, Department of the US Army, Fonds de recherche du Québec – Santé, Fonds de recherche du Québec – Nature et technologies, and Scoliosis Research Society. He has focused his research on acute predictors of the outcome after a traumatic spinal cord injury, and on the biomechanical and experimental characterization of traumatic spinal cord injury.Education:École Polytechnique de Montréal, Canada, B.Eng, 1997, Mechanical engineering

Université de Montréal, Canada, M.S., 2001, Biomedical sciences

Université de Montréal, Canada, M.D., 2002, Medicine

Université de Montréal, Canada, Residency, 2007, Orthopedic Surgery

Université de Montréal, Canada, Ph.D., 2008, Biomedical sciences

Twin Cities Spine Center, Fellowship, 2008, Spine surgeryThis author has no relevant disclosures.

152Relationships between Specific Functional Abilities and Health-Related Quality of Life in Chronic Spinal Cord InjuryFriday, May 04, 2018 09:15 AM - 10:15 AMLearning Objectives:Determine the functional priorities associated with the quality of life of patients in the chronic phase after a traumatic spinal cord injury.

Participants:Goulet J, Mac-Thiong JUniversité De Montréal , Montreal , Quebec, CanadaJulien Goulet, MDUniversité De Montréal Bio:Julien Goulet, MD, is a post-graduate year 4 resident in orthopaedic surgery at the University of Montreal. He is implicated in the Spine and Trauma divisions of the Orthopaedic Research Centre at the Sacré-Coeur Hospital in Montreal. His work on spinal cord injury has been supported by Fonds de recherche du Québec – Santé and Fondation de recherche et d'éducation en orthopédie de Montréal under the mentorship of Dr Jean-Marc Mac-Thiong. Education:Université de Montréal (Montreal, Qc, Canada), MD 2010-2014, Medicine

Université de Montréal (Montreal, Qc, Canada), Orthopaedic Surgery 2014 - ...

This author has the following disclosures: Research Support

Fonds de recherche du Québec – SantéJean-Marc Mac-Thiong, MD, PhDUniversité De Montréal Bio:Jean-Marc Mac-Thiong, MD, PhD, is a clinician-scientist practicing as an orthopedic spine surgeon at the Hopital du Sacre-Coeur de Montreal, with a multidisciplinary background in spine surgery (MD, fellowship), biomedical sciences (MSc, PhD), and engineering (BEng). He is an associate professor of surgery and research director of the Orthopedics Division at Université de Montréal. He is Chairman of the Medtronic Research Chair in spinal trauma at Université de Montréal and in charge of the Rick Hansen Spinal Cord Injury Registry at Hopital du Sacre-Coeur de Montreal. He is Chair of the Spine/Acute care Committee at the American Spinal Injury Association. His research has been supported by the Canadian Funds for Innovation, Natural Sciences and Engineering Research Council of Canada, Department of the US Army, Fonds de recherche du Québec – Santé, Fonds de recherche du Québec – Nature et technologies, and Scoliosis Research Society. He has focused his research on acute predictors of the outcome after a traumatic spinal cord injury, and on the biomechanical and experimental characterization of traumatic spinal cord injury. Education:École Polytechnique de Montréal (Montreal, Qc, Canada), B.Eng. 1997 Mechanical Engineering

Université de Montréal (Montreal, Qc, Canada), M.S. 2001 Biomedical Sciences

Université de Montréal (Montreal, Qc, Canada), MD 2002 Medicine

Université de Montréal (Montreal, Qc, Canada ), Residendy 2007 Orthopaedic Surgery

Université de Montréal (Montreal, Qc, Canada), Ph.D. 2008 Biomedical Sciences

Twin Cities Spine Center (Minneapolis, MN), Fellowship 2008 Spine Surgery This author has the following disclosures:

Research SupportFonds de recherche du Québec – Santé

153Activity-based training with spinal cord epidural stimulation for the recovery of standing in individuals with chronic motor complete spinal cord injuryFriday, May 04, 2018 09:15 AM - 10:15 AMLearning Objectives:

Discuss how activity-based training with spinal cord epidural stimulation can be optimized for improving standing motor function in chronic, motor complete spinal cord injured individuals.

Participants:Rejc E, Angeli C, Harkema SUniversity of Louisville , Louisville , KY, USAEnrico Rejc, PhDUniversity of Louisville Bio:Dr. Rejc is currently Assistant Professor and Scientific Director of the Metabolic, Neuromuscular and Skeletal research core at the Kentucky Spinal Cord Injury Research Center, University of Louisville. He received his Ph.D. in Exercise Physiology from University of Udine (Italy), and has been involved in research activities at the Department of Integrative Biology and Physiology, UCLA, and at the Institute for Biophysical and Clinical Research into Human Movement, MMU (UK). Presently, the main topic of his research activity deals with the interactive effects of lumbosacral spinal cord epidural stimulation and activity-based rehabilitation on motor function for standing in individuals with severe spinal cord injury. He also studies the effects of different training interventions on lower limb muscle properties.Education:University of Udine (Italy), BS (2000-2004), Human Movement Science

University of Udine (Italy), MS (2004-2007), Sport Science

University of Udine (Italy), PhD (2008-2010), Exercise Physiology

University of Udine (Italy), Research Fellowship (2011-2012), Human Movement Science

University of Louisville (Louisville, KY), Postdoc (2012-15), Spinal Cord Injury This author has no relevant disclosures.Claudia Angeli, PhDUniversity of Louisville Bio:-Education:-This author has no relevant disclosures.Susan Harkema, PhDUniversity of Louisville This author has the following disclosures:

Research SupportThis work was supported by: United States National Institutes of Health, National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the award number R01EB007615 and National Intitute of General Medical Sciences (NIGMS) P30 GM103507; the Leona M. and

Harry B. Helmsley Charitable Trust; Christopher and Dana Reeve Foundation; Kessler Foundation; Jewish Hospital and St. Mary’s Foundation; and Medtronic plc.

154Standardized Locomotor Training Across Eight Clinical Sites: Outcomes from the Reeve Foundation NeuroRecovery Network 2005-2016Friday, May 04, 2018 09:15 AM - 10:15 AMLearning Objectives:1. Review outcomes associated with participation in a standardized locomotor training (LT) program after spinal cord injury (SCI)

Participants:1Tefertiller C, 2Behrman A, 3Schmidt Read M, 3Watson E, 4Forrest G, 5Basso M, 6Morrison S, 2Atkinson K, 7Taylor H, 8Ugilweneza B, 8Lorenz D, 9Harkema S1Craig Hospital , Englewood , CO, USA; 2Frazier Rehabilitation Institute , Louisville , KY, USA; 3Magee Rehabilitation , Philadelphia , PA, USA; 4Kessler Foundation , West Orange , NJ, USA; 5Ohio State University , Columbus , OH, USA; 6Shepherd Center , Atlanta , GA, USA; 7Tirr , Houston , TX, USA; 8Kentucky Spinal Cord Injury Research Center Department of Neurosurgery, School of Medicine Department of Health Management and Systems Science, School of Public Health and Information Sciences , Louisville , KY, USA; 9Kentucky Spinal Cord Injury Research Center, Frazier Rehabilitation Institute , Louisville , KY, USACandy Tefertiller, PT, DPT, NCSCraig Hospital Bio:Candy Tefertiller, PT, DPT, ATP, NCS is the Director of Physical Therapy at Craig Hospital. Candy received a B.S in Biology from Mount Olive College in 1997 and a Master’s in Physical Therapy from East Carolina University in 2000. She then completed a Doctorate of Physical Therapy degree from Rocky Mountain Health Care University in 2008. Candy has been working in the field of neurological rehabilitation since 2000 and received an assistive technology practitioner (ATP) certification in 2005 and became a certified neurological clinical specialist (NCS) in 2007. She has been involved in numerous research projects and has focused much of her career on interventions and program development promoting recovery after neurologic injury or disease. Candy is a member of the American Physical Therapy Association and the Neurologic Section. Education:Rocky Mountain Health Care University, Sandy UT 2008-2009: Doctorate of Physical Therapy

East Carolina University, Greenville NC 1997-200: Master in Physical Therapy

Mount Olive College, Mount Olive, NC: Bachelor's in Biology

Casper College, Casper Wy: Associate's degree in Communication This author has the following disclosures:

Research Support

Since 2014, this project was funded by the Christopher & Dana Reeve Foundation. It was supported, in part, by cooperative agreement numbers 90PR3001 and 90PR3002, from the U.S. Administration for Community Living, Department of Health and Human Services, Washington, D.C. 20201. Grantees undertaking projects under government sponsorship are encouraged to express freely their findings and conclusions. Points of view or opinions do not, therefore, necessarily represent official Administration for Community Living policy. Prior to 2014, this project was funded by the Christopher & Dana Reeve Foundation through various cooperative agreements with the Centers for Disease Control and Prevention (cooperative agreement numbers 1U59DD000838, 1U59DD000338, and U10/CCU220379). Andrea Behrman, PhDFrazier Rehabilitation Institute This author has the following disclosures:

Research SupportSince 2014, this project was funded by the Christopher & Dana Reeve Foundation. It was supported, in part, by cooperative agreement numbers 90PR3001 and 90PR3002, from the U.S. Administration for Community Living, Department of Health and Human Services, Washington, D.C. 20201. Grantees undertaking projects under government sponsorship are encouraged to express freely their findings and conclusions. Points of view or opinions do not, therefore, necessarily represent official Administration for Community Living policy. Prior to 2014, this project was funded by the Christopher & Dana Reeve Foundation through various cooperative agreements with the Centers for Disease Control and Prevention (cooperative agreement numbers 1U59DD000838, 1U59DD000338, and U10/CCU220379). Mary Schmidt Read, PT, DPT, MSMagee Rehabilitation This author has the following disclosures:

Research SupportSince 2014, this project was funded by the Christopher & Dana Reeve Foundation. It was supported, in part, by cooperative agreement numbers 90PR3001 and 90PR3002, from the U.S. Administration for Community Living, Department of Health and Human Services, Washington, D.C. 20201. Grantees undertaking projects under government sponsorship are encouraged to express freely their findings and conclusions. Points of view or opinions do not, therefore, necessarily represent official Administration for Community Living policy. Prior to 2014, this project was funded by the Christopher & Dana Reeve Foundation through various cooperative agreements with the Centers for Disease Control and Prevention (cooperative agreement numbers 1U59DD000838, 1U59DD000338, and U10/CCU220379). Elizabeth Watson, PT, DPT, NCSMagee Rehabilitation This author has the following disclosures:

Research SupportSince 2014, this project was funded by the Christopher & Dana Reeve Foundation. It was supported, in part, by cooperative agreement numbers 90PR3001 and 90PR3002, from the U.S. Administration for Community Living, Department of Health and Human Services, Washington, D.C. 20201. Grantees undertaking projects under government sponsorship are encouraged to express freely their findings and conclusions. Points of view or opinions do not, therefore,

necessarily represent official Administration for Community Living policy. Prior to 2014, this project was funded by the Christopher & Dana Reeve Foundation through various cooperative agreements with the Centers for Disease Control and Prevention (cooperative agreement numbers 1U59DD000838, 1U59DD000338, and U10/CCU220379). Gail Forrest, PhDKessler Foundation This author has the following disclosures:

Research SupportSince 2014, this project was funded by the Christopher & Dana Reeve Foundation. It was supported, in part, by cooperative agreement numbers 90PR3001 and 90PR3002, from the U.S. Administration for Community Living, Department of Health and Human Services, Washington, D.C. 20201. Grantees undertaking projects under government sponsorship are encouraged to express freely their findings and conclusions. Points of view or opinions do not, therefore, necessarily represent official Administration for Community Living policy. Prior to 2014, this project was funded by the Christopher & Dana Reeve Foundation through various cooperative agreements with the Centers for Disease Control and Prevention (cooperative agreement numbers 1U59DD000838, 1U59DD000338, and U10/CCU220379). Michelle Basso, Ed.D, PTOhio State University This author has the following disclosures:

Research SupportSince 2014, this project was funded by the Christopher & Dana Reeve Foundation. It was supported, in part, by cooperative agreement numbers 90PR3001 and 90PR3002, from the U.S. Administration for Community Living, Department of Health and Human Services, Washington, D.C. 20201. Grantees undertaking projects under government sponsorship are encouraged to express freely their findings and conclusions. Points of view or opinions do not, therefore, necessarily represent official Administration for Community Living policy. Prior to 2014, this project was funded by the Christopher & Dana Reeve Foundation through various cooperative agreements with the Centers for Disease Control and Prevention (cooperative agreement numbers 1U59DD000838, 1U59DD000338, and U10/CCU220379). Sarah Morrison, PT, MBAShepherd Center This author has the following disclosures:

Research SupportSince 2014, this project was funded by the Christopher & Dana Reeve Foundation. It was supported, in part, by cooperative agreement numbers 90PR3001 and 90PR3002, from the U.S. Administration for Community Living, Department of Health and Human Services, Washington, D.C. 20201. Grantees undertaking projects under government sponsorship are encouraged to express freely their findings and conclusions. Points of view or opinions do not, therefore, necessarily represent official Administration for Community Living policy. Prior to 2014, this project was funded by the Christopher & Dana Reeve Foundation through various cooperative agreements with the Centers for Disease Control and Prevention (cooperative agreement numbers 1U59DD000838, 1U59DD000338, and U10/CCU220379).

Kimberly Atkinson, PT, DPTFrazier Rehabilitation Institute This author has the following disclosures:

Research SupportSince 2014, this project was funded by the Christopher & Dana Reeve Foundation. It was supported, in part, by cooperative agreement numbers 90PR3001 and 90PR3002, from the U.S. Administration for Community Living, Department of Health and Human Services, Washington, D.C. 20201. Grantees undertaking projects under government sponsorship are encouraged to express freely their findings and conclusions. Points of view or opinions do not, therefore, necessarily represent official Administration for Community Living policy. Prior to 2014, this project was funded by the Christopher & Dana Reeve Foundation through various cooperative agreements with the Centers for Disease Control and Prevention (cooperative agreement numbers 1U59DD000838, 1U59DD000338, and U10/CCU220379). Heather Taylor, PhDTirr This author has the following disclosures:

Research SupportSince 2014, this project was funded by the Christopher & Dana Reeve Foundation. It was supported, in part, by cooperative agreement numbers 90PR3001 and 90PR3002, from the U.S. Administration for Community Living, Department of Health and Human Services, Washington, D.C. 20201. Grantees undertaking projects under government sponsorship are encouraged to express freely their findings and conclusions. Points of view or opinions do not, therefore, necessarily represent official Administration for Community Living policy. Prior to 2014, this project was funded by the Christopher & Dana Reeve Foundation through various cooperative agreements with the Centers for Disease Control and Prevention (cooperative agreement numbers 1U59DD000838, 1U59DD000338, and U10/CCU220379). Beatrice Ugilweneza, PhDKentucky Spinal Cord Injury Research Center Department of Neurosurgery, School of Medicine Department of Health Management and Systems Science, School of Public Health and Information Sciences This author has the following disclosures:

Research SupportSince 2014, this project was funded by the Christopher & Dana Reeve Foundation. It was supported, in part, by cooperative agreement numbers 90PR3001 and 90PR3002, from the U.S. Administration for Community Living, Department of Health and Human Services, Washington, D.C. 20201. Grantees undertaking projects under government sponsorship are encouraged to express freely their findings and conclusions. Points of view or opinions do not, therefore, necessarily represent official Administration for Community Living policy. Prior to 2014, this project was funded by the Christopher & Dana Reeve Foundation through various cooperative agreements with the Centers for Disease Control and Prevention (cooperative agreement numbers 1U59DD000838, 1U59DD000338, and U10/CCU220379). Doug Lorenz, PhDKentucky Spinal Cord Injury Research Center Department of Neurosurgery, School of Medicine

Department of Health Management and Systems Science, School of Public Health and Information Sciences This author has the following disclosures:

Research SupportSince 2014, this project was funded by the Christopher & Dana Reeve Foundation. It was supported, in part, by cooperative agreement numbers 90PR3001 and 90PR3002, from the U.S. Administration for Community Living, Department of Health and Human Services, Washington, D.C. 20201. Grantees undertaking projects under government sponsorship are encouraged to express freely their findings and conclusions. Points of view or opinions do not, therefore, necessarily represent official Administration for Community Living policy. Prior to 2014, this project was funded by the Christopher & Dana Reeve Foundation through various cooperative agreements with the Centers for Disease Control and Prevention (cooperative agreement numbers 1U59DD000838, 1U59DD000338, and U10/CCU220379). Susan Harkema, PhDKentucky Spinal Cord Injury Research Center, Frazier Rehabilitation Institute This author has the following disclosures:

Research SupportSince 2014, this project was funded by the Christopher & Dana Reeve Foundation. It was supported, in part, by cooperative agreement numbers 90PR3001 and 90PR3002, from the U.S. Administration for Community Living, Department of Health and Human Services, Washington, D.C. 20201. Grantees undertaking projects under government sponsorship are encouraged to express freely their findings and conclusions. Points of view or opinions do not, therefore, necessarily represent official Administration for Community Living policy. Prior to 2014, this project was funded by the Christopher & Dana Reeve Foundation through various cooperative agreements with the Centers for Disease Control and Prevention (cooperative agreement numbers 1U59DD000838, 1U59DD000338, and U10/CCU220379).

155A functional electrical stimulation rowing exercise program interrupts expected bone loss after SCIFriday, May 04, 2018 09:15 AM - 10:15 AMLearning Objectives:Illustrate the potential of an FES rowing exercise program to slow or reverse bone loss in the distal femur after SCI.

Participants:1Lambach R, 2Stafford N, 1Kolesar J, 1Kiratli J, 1Creasey G, 3Gibbons R, 4Andrews B, 1Beaupre G1Va Palo Alto Health Care System , Palo Alto , CA, USA; 2Stanford University , Stanford , CA, USA; 3University College London , London , , United kingdom; 4University of Warwick , Coventry , , United kingdomRebecca Lambach, PhDVa Palo Alto Health Care System

Bio:Rebecca Lambach, PhD, is a Research Biomedical Engineer in the Musculoskeletal Research Laboratory at the VA Palo Alto Health Care System in Palo Alto, CA, and a Postdoctoral Scholar in the Department of Neurosurgery at Stanford University. Dr. Lambach received her BS in Engineering from Hope College in 2007 and her MS and PhD in Mechanical Engineering from The Ohio State University in 2009 and 2014 respectively. Dr. Lambach has more than nine years of interdisciplinary biomechanics research experience using human movement analysis and musculoskeletal modeling to evaluate movement patterns and rehabilitation techniques and their influences on health and quality of life. Dr. Lambach received a VA Rehabilitation Research & Development Level One Career Development Award in 2016.Education:Hope College (Holland, MI), BS 2003-2007 Engineering

The Ohio State University (Columbus, OH), MS 2007-2009 Mechanical Engineering

The Ohio State University (Columbus, OH) PhD 2009-2014 Mechanical Engineering

Stanford University (Stanford, CA) Postdoctoral Scholar 2016-2017 Department of NeurosurgeryThis author has no relevant disclosures.Nicole Stafford, BSStanford University This author has no relevant disclosures.Julie Kolesar, PhDVa Palo Alto Health Care System This author has no relevant disclosures.Jenny Kiratli, PhDVa Palo Alto Health Care System This author has no relevant disclosures.Graham Creasey, MDVa Palo Alto Health Care System This author has no relevant disclosures.Robin Gibbons, PhDUniversity College London This author has no relevant disclosures.Brian Andrews, PhDUniversity of Warwick This author has no relevant disclosures.Gary Beaupre, PhDVa Palo Alto Health Care System This author has no relevant disclosures.

156

Zoledronic acid attenuates bone loss following complete traumatic spinal cord injury Friday, May 04, 2018 09:15 AM - 10:15 AMLearning Objectives:The learner will recognize potential differences in bone loss outcomes between patients receiving standard rehabilitation and those who receive the same rehabilitation as well as an IV bisphosphonate 2-3 weeks after the onset of SCI.

The learner will understand possible assessment tools that can measure bone loss during the acute rehabilitation, 0-4 months post injury.

Participants:1Oleson C, 1Marino R, 2Formal C, 3Modlesky C1Thomas Jefferson University , Philadelphia , PA, United states; 2Magee Rehabilitation Hospital , Philadelphia , PA, United states; 3University of Georgia , Athens , GA, United statesChristina Oleson, MDThomas Jefferson University Bio:Christina V. Oleson MD is an Associate Professor of Rehabilitation Medicine at Thomas Jefferson University, Philadelphia PA. She is board-certified in both Physical Medicine/Rehabilitation and in Spinal Cord Injury Medicine. Dr. Oleson earned her BA from Harvard University and her MD at the University of Massachusetts at Worcester. Following residency in Physical Medicine and Rehabilitation at Thomas Jefferson University, Dr. Oleson completed a Spinal Cord Injury Medicine fellowship at the Rehabilitation Institute of Chicago at Northwestern University. She is the recipient of a Young Investigator Award from the American Society for Bone and Mineral Research as well as the G. Heiner Sell Research Award for her work in vitamin D deficiency in those with motor complete SCI. Dr. Oleson has also published in the area of functional outcomes in those with motor complete SCI examining the effects of pinprick and more recently pinprick with age. Her early work on motor recovery earned an Educational and Research Foundation Best Paper Award from the American Academy of Physical Medicine and Rehabilitation. Dr. Oleson’s current research focuses on immobilization osteoporosis in those with traumatic SCI. She serves as the principal investigator in a NIDILRR-funded Investigational study examining potential benefits of zoledronic acid in preserving bone density following acute traumatic SCI. In May of 2017, she published Osteoporosis Rehabilitation: A Practical Approach, a 500-page work examining the diagnosis, medical management and functional rehabilitation needs of patients experiencing the effects of osteoporosis.

Education:A.B. Harvard University, Cambridge, MA. Biology, 1992

M.D. University of Massachusetts, Worcester, MA. 1999

Residency, PM and R: Thomas Jefferson University, Philadelphia, PA. 2003

SCI Medicine Fellowship, Rehabilitation Institute of Chicago and McGaw Medical Center, Northwestern University, Chicago, IL. 2004This author has the following disclosures:

Research SupportNiDDLR grantRalph Marino, MDThomas Jefferson University This author has the following disclosures:

Research SupportNiDDLR grant and Craig Neilson FoundationChristopher Formal, MDMagee Rehabilitation Hospital This author has no relevant disclosures.Christopher Modlesky, PhDUniversity of Georgia This author has the following disclosures:

Research Support

R01 HD090126 Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD

157Shifting the paradigm: Why some pressure injuries may be unpreventable for individuals with spinal cord injuryFriday, May 04, 2018 09:15 AM - 10:15 AMLearning Objectives:• Describe relationships between tissue resilience and gluteal muscle quality

Participants:1Bogie K, 2Henzel K, 2Richmond M, 2Alvarado N, 2McDaniel J, 2Graebert J, 2Schwartz K, 2Lemmer D, 2Seton J, 3Li Y, 3Sun J1Case Western Reserve University/Louis Stokes Cleveland Va Medical Center , Cleveland , OH, USA; 2Louis Stokes Cleveland Va Medical Center , Cleveland , OH, USA; 3Case Western Reserve University , Cleveland , OH, USAKath Bogie, D.PhilCase Western Reserve University/Louis Stokes Cleveland Va Medical Center Bio:Dr. Kath Bogie is a biomedical engineer who pursues translational research focused on improving patient-centered wound management. Dr. Bogie trained in England at the University of Manchester Institute of Science and Technology followed by a D.Phil in Biomedical Engineering from the University of Oxford. She is currently an Associate Professor in the Dept of Orthopaedics at Case Western Reserve University. At the Cleveland Dept of Veterans Affairs

Medical Center Dr. Bogie is a Senior Research Scientist and Director of Health Maintenance and Monitoring within the Advanced Platform Technology Center. Current interdisciplinary translational research include determination of personalized pressure injury risk based on identification of novel biomarkers, using bioinformatics to enable the development of a personalized healthcare tool for pressure injury prevention planning and development of a smart electroceutical bandage to deliver effective wound therapy outside traditional clinical settings.Education:University of Manchester Institute of Science and Technology, Manchester, UK B.Sc.(Hons.) 1984 Metals and Materials Technology

University of Oxford, Oxford, UK D.Phil. 1998 Biomedical Engineering This author has the following disclosures:

Research SupportKristi Henzel, MD, PhDLouis Stokes Cleveland Va Medical Center This author has no relevant disclosures.MaryAnn Richmond, MD, DVMLouis Stokes Cleveland Va Medical Center This author has no relevant disclosures.Nannette Alvarado, MDLouis Stokes Cleveland Va Medical Center This author has no relevant disclosures.John McDaniel, PhDLouis Stokes Cleveland Va Medical Center This author has the following disclosures:

Research SupportJennifer Graebert, BALouis Stokes Cleveland Va Medical Center This author has the following disclosures:

Research SupportKatie Schwartz, Louis Stokes Cleveland Va Medical Center This author has the following disclosures:

Research SupportDavid Lemmer, Louis Stokes Cleveland Va Medical Center This author has the following disclosures:

Research SupportJacinta Seton, Louis Stokes Cleveland Va Medical Center This author has the following disclosures:

Research Support

Youjun Li, Case Western Reserve University This author has the following disclosures:

Research SupportJiayang Sun, PhDCase Western Reserve University This author has the following disclosures:

Research Support

158Core Temperature Lability during Heat Exposure Predicts Cognitive Performance in Persons with Spinal Cord InjuryFriday, May 04, 2018 09:15 AM - 10:15 AMLearning Objectives:Determine the effects of heat exposure on core body temperature and cognition in persons with high-level spinal cord injury and the variability of those effects due to differences in thermodysregulation.

Participants:1Kumar N, 2Graham M, 2Leung P, 1Tittley T, 1Tascione O, 3Bang C, 1Bauman W, 1Handrakis J1Va Rr&D National Center for the Medical Consequences of Spinal Cord Injury, James J. Peters Vamc , Bronx , NY, USA; 2New York Institute of Technology, Department of Physical Therapy, School of Health Professions , Old Westbury , NY, USA; 3Medical Service, James J. Peters Vamc , Bronx , NY, USANina Kumar, BSVa Rr&D National Center for the Medical Consequences of Spinal Cord Injury, James J. Peters Vamc This author has no relevant disclosures.Marin Graham, BS, SPTNew York Institute of Technology, Department of Physical Therapy, School of Health Professions This author has no relevant disclosures.Patricia Leung, BS, SPTNew York Institute of Technology, Department of Physical Therapy, School of Health Professions This author has no relevant disclosures.Tishina Tittley, BAVa Rr&D National Center for the Medical Consequences of Spinal Cord Injury, James J. Peters Vamc This author has no relevant disclosures.Oriana Tascione, BSVa Rr&D National Center for the Medical Consequences of Spinal Cord Injury, James J. Peters Vamc

This author has no relevant disclosures.Charlene Bang, PsyDMedical Service, James J. Peters Vamc This author has no relevant disclosures.William Bauman, MDVa Rr&D National Center for the Medical Consequences of Spinal Cord Injury, James J. Peters Vamc This author has no relevant disclosures.John Handrakis, PT, DPT, EdD, NCSVa Rr&D National Center for the Medical Consequences of Spinal Cord Injury, James J. Peters Vamc Bio:John P. Handrakis, PT, DPT, EdD, NCS is a Professor in the department of Physical Therapy at New York Institute of Technology (NYIT) and specializes in neurological rehabilitation. In addition to teaching, Dr. Handrakis heads the Thermoregulation Research Program at the Veterans Affairs Rehabilitation Research and Development National Center for the Medical Consequences of Spinal Cord Injury at the James J. Peters VA Medical Center. After graduating with a Bachelor’s degree from Fordham University in 1978, he attended Columbia University, College of Physicians and Surgeons where he graduated in 1981 with a degree in Physical Therapy. While practicing at the Rusk Institute of Rehabilitation Medicine at NYU Langone Medical Center, Dr. Handrakis earned a Master of Science degree in Exercise Physiology from Long Island University in 1985. He later returned to Columbia University, Teachers College where he earned a doctoral degree in Applied Physiology in 2008 and a doctoral degree in Physical Therapy from New York Institute of Technology in 2010. He is recognized as a Neurologic Clinical Specialist (NCS) by the American Board of Physical Therapy Specialties (ABPTS) and is a Neurology Section member of the American Physical Therapy Association (APTA), a current member of Academy of Spinal Cord Injury Professionals (ASCIP), and of American Spinal Injury Association (ASIA). Dr. Handrakis was nominated to be a member of the ASIA Autonomics Standards Committee and to chair the thermoregulation subcommittee. Current goals of the subcommittee are to improve the validity and reliability of assessing the degree of remaining autonomic nervous system function after spinal cord injury (SCI), specifically in the area of thermoregulation. Dr. Handrakis has had research funding from the Craig H. Neilsen Foundation and RR&D Small Projects in Rehabilitation Research (SPiRE). His research focuses on the regulation of core body temperature after SCI and the impact of thermodysregulation on cognition. He aims to develop interventions to stabilize core temperature and optimize cognitive performance for persons with SCI in all environments, during all seasons.Education:Fordham University (Bronx, NY), 1978 Bachelor of Science, General Science

Columbia University (New York, NY), 1981 Certificate in Physical Therapy

Long Island University (Brooklyn, NY), 1985 Master of Science, Exercise Physiology

Columbia University, Teachers College, School of Biobehavioral Sciences (New York, NY),

2008 Doctor of Education, Applied Physiology

New York Institute of Technology, School of Health Professions (Old Westbury, NY), 2010 Doctor of Physical TherapyThis author has no relevant disclosures.

159Should we measure or estimate energy expenditure in spinal cord injury patients? A comparison of indirect calorimetry and commonly used predictive equationsFriday, May 04, 2018 09:15 AM - 10:15 AMLearning Objectives:The objective of this study is to compare the measured resting metabolic rate (m-RMR) with estimated RMR (e-RMR) using predictive equations

Participants:1Wong S, 1Subong P, 1Pandey A, 2Toumpi M, 1Saif M, 1Graham A1National Spinal Injuries Centre, Stoke Mandeville Hospital , Aylesbury , , United kingdom; 2The Health Lab , Athens , , GreeceSamford Wong, MSc (Med Sci)., PhD., RDNational Spinal Injuries Centre, Stoke Mandeville Hospital Bio:Samford Wong is NSIC Dietetic Lead in Research / Lead Dietitian, National Spinal Injuries Centre, Stoke Mandeville Hospital Department of Nutrition and Dietetics, Stoke Mandeville Hospital, Buckinghamshire Healthcare NHS Trust, Aylesbury HP21 8AL; Tel: 01296 315775 Education:Education: 2004: BSc (Hons)., RD; 2006: MSc (Med Sci); 2010; Dip Adv Diet: 2011; 2012: MPhil / PhD PTLLS: 2013; CMS: 2014This author has the following disclosures:

Research SupportResearch Grant form Yakult HonshaPaul Subong, RNNational Spinal Injuries Centre, Stoke Mandeville Hospital This author has no relevant disclosures.Alka Pandey, RDNational Spinal Injuries Centre, Stoke Mandeville Hospital This author has no relevant disclosures.

Mria Toumpi, MSc., RDThe Health Lab This author has no relevant disclosures.Mofid Saif, MD., FRCP., FRCSNational Spinal Injuries Centre, Stoke Mandeville Hospital This author has no relevant disclosures.Allison Graham, MD., FRCPNational Spinal Injuries Centre, Stoke Mandeville Hospital This author has no relevant disclosures.

160Cardiac consequences of spinal cord injury: a meta-analysisFriday, May 04, 2018 09:15 AM - 10:15 AM

Participants:Williams A, Gee C, Voss C, West CUniversity of British Columbia , Vancouver , BC, CanadaAlexandra Williams, PhDUniversity of British Columbia Bio:Alexandra M. Williams, PhD, is a postdoctoral fellow at the University of British Columbia (UBC) and the International Collaboration on Repair Discoveries (ICORD). After completing a Bachelor of Medial Science and Master of Science in human physiology at The University of Western Ontario (Canada), she joined the Centre for Heart, Lung and Vascular Health at UBC's Okanagan Campus for her doctoral studies with Dr. Neil Eves. During that time, she developed an advanced technical skillset for the assessment of cardiac function, and completed a series of studies regarding sex-related differences in the mechanical function and autonomic control of the heart. After completing her PhD in 2016, she joined the UBC Nepal Expedition as a lead cardiac sonographer for a collection of cardiovascular studies in the Himalayas alongside world-leading integrative physiologists and high-altitude physicians. In 2017 she began as a postdoctoral fellow with Dr. Christopher West and Dr. Brian Kwon to investigate alterations to the heart's structure and function following spinal cord injury. Dr. Williams has received research funding and awards from the Natural Sciences and Engineering Research Council of Canada (NSERC), Heart and Stroke Foundation of Canada (HSFC), Michael Smith Foundation for Health Research, Rick Hansen Institute and the International Collaboration on Repair Discoveries. Education:Doctor of Philosophy (PhD), Cardiac Physiology, University of British Columbia, Canada, 2012-2016

Master of Science (MSc), Exercise Physiology, University of Western Ontario, Canada, 2009-2011

Honours, Bachelor of Medical Science (BMSc), Physiology, University of Western Ontario, Canada, 2005-2009

This author has no relevant disclosures.Cameron Gee, MScUniversity of British Columbia This author has no relevant disclosures.Christine Voss, PhDUniversity of British Columbia This author has no relevant disclosures.Christopher West, PhDUniversity of British Columbia This author has no relevant disclosures.

161OnabotulinumtoxinA for neurogenic detrusor overactivity not only reduces the frequency and severity of autonomic dysreflexia safely but significantly improves quality of life for individuals with spinal cord injuryFriday, May 04, 2018 09:15 AM - 10:15 AMLearning Objectives:To provide evidence that treatment of NDO (Botox) not only reduces AD objectively, but more importantly improves subjective measures of quality of life in individuals with SCI significantly.

Participants:1Kran S, 1Walter M, 2Nigro M, 2Stothers L, 2Rapoport D, 2Kavanagh A, 1Krassioukov A1International Collaboration on Repair Discoveries (Icord), Faculty of Medicine, University of British Columbia , Vancouver , BC, Canada; 2Department of Urologic Sciences, Faculty of Medicine, University of British Columbia , Vancouver , BC, CanadaStephanie Kran, BScInternational Collaboration on Repair Discoveries (Icord), Faculty of Medicine, University of British Columbia Bio:Stephanie L. Kran, BSc, is a research assistant at the International Collaboration on Repair Discoveries (ICORD) and a medical student at the University of British Columbia in Vancouver, Canada. She received degrees in Biology and Kinesiology at the University of Victoria, British Columbia, and practiced as a Kinesiologist in Ontario before starting medical school in 2016. She is a co-author of “The Walking Dead Psychology: Psych of the Living Dead”, which focused on the theoretical neurobiology of zombies. Mrs. Kran has presented at national conferences on the physiological demands of high-intensity interval training, and is currently researching the use of Botox for the treatment of bladder-related autonomic dysreflexia in individuals with spinal cord injury. Education:University of Victoria (Victoria, BC, Canada), BS 2007-2013 Biology

University of Victoria (Victoria, BC, Canada), BS 2013-2015 Kinesiology

University of British Columbia (Vancouver, BC, Canada), MD 2016 – Present (graduation 2020) Medicine This author has the following disclosures:

Research Support2017 Faculty of Medicine Summer Student Research Program and the Florence E. Heighway Summer Research Award RecipientMatthias Walter, MD, FEBUInternational Collaboration on Repair Discoveries (Icord), Faculty of Medicine, University of British Columbia This author has the following disclosures:

Research Support2017 Michael Smith Foundation for Health Related (MSFHR) Postdoctoral Research Trainee Award Recipient, co-funded by the Rick Hansen Institute (RHI); WellSpect Research Grant-in-Aid RecipientMark Nigro, MD, FRCSCDepartment of Urologic Sciences, Faculty of Medicine, University of British Columbia This author has no relevant disclosures.Lynn Stothers, MD, FRCSCDepartment of Urologic Sciences, Faculty of Medicine, University of British Columbia This author has no relevant disclosures.Daniel Rapoport, MD, FRCSCDepartment of Urologic Sciences, Faculty of Medicine, University of British Columbia This author has no relevant disclosures.Alex Kavanagh, PEng, MPH, MD, FRCSCDepartment of Urologic Sciences, Faculty of Medicine, University of British Columbia This author has no relevant disclosures.Andrei Krassioukov, MD, PhD, FRCPCInternational Collaboration on Repair Discoveries (Icord), Faculty of Medicine, University of British Columbia This author has the following disclosures:

Research Support Other (see below)

ONGOING RESEARCH SUPPORT 1. Craig H. Neilsen Foundation QOL Project Grants. Title: Motherhood after spinal cord injury: lactation, breastfeeding, and autonomic dysreflexia. Period: 2016-2017 ROLE: PI

2. Heart and Stroke GIA 2016/17. Title: When are blood vessels “ready to rupture”? Cerebrovascular health following spinal cord injury: from animal models to clinical practice. Period: 2016 – 2019 ROLE: PI

3. Pfizer Canada Inc. Title: A Phase II, Open-Label Exploratory Study Investigating the

Efficacy of Toviaz for Treatment of Adult Patients with Spinal Cord Injury (SCI) with Neurogenic Detrusor Overactivity (NDO) for Amelioration of Autonomic Dysreflexia (AD). Period: Nov 2015 –Feb 2017 ROLE: PI

4. Rick Hansen Institute. Title: Development of a mobile app (telephone/iPod application) for emergency department physicians on recognition and management of life-threatening episodes of autonomic dysreflexia: “ABC of AD for the EM doc”. Period: Apr 2015-Dec 2016. ROLE: PI

5. Vancouver Foundation. Title: Vancouver Foundation Start-up Funds: Period: April 2015 – March 2017 ROLE: PI

6. Christopher and Dana Reeve Foundation. Title: Big Idea Cardiovascular Committee. Period: Feb 2015-Aug2015. ROLE: PI

7. Rick Hansen Institute/ RHI Pilot Studies - Optimizing Neurorecovery Following SCI. Title: Effect of epidural stimulation on cardiovascular control following spinal cord injury. Period: Mar 2015-Mar 2017. ROLE: PI

8. Rick Hansen Foundation/International Collaboration On Repair Discoveries (ICORD)/Seed Grants. Title: Development of evidence-based guidelines for blood pressure management during iatrogenically-induced autonomic dysreflexia in those with spinal cord injury: the limits of cerebral autoregulation. Period: Apr 2014-Jun 2016. PI: Dr. Stacy Elliott. ROLE: Co-Investigator

9. Department of Defense USA. Title: Alleviating autonomic dysreflexia after spinal cord injury. Period: September 2014-August 2017. ROLE: PI

10. Craig H. Neilsen Foundation/ Neilsen Senior Research Grant. Title: Cardiac function after spinal cord injury: from bench to bedside. Period: July 2013-June 2017. ROLE: PI 11. Rick Hansen Institute. Title: Validation of the International Autonomic Standards for evaluation of individuals with chronic spinal cord injury. Period: March 2013- March 2017. ROLE: PI

12. Rick Hansen Foundation. Title: Improving Cardiovascular Health for Canadians Living with SCI: Effects of Exercise, sex Differences, and Targeted Clinical Education.

Period: April 2012-March 2017. ROLE: PI

13. Rick Hansen Institute / Operating Grant. Title: BOTOX treatment for neurogenic detrusor hyperreflexia and prevention of autonomic dysreflexia following spinal cord injury. Period: July 2012 – Jan. 2017. ROLE: PI

14. Canadian Institutes of Health Research (CIHR) / Chronic disease risk and intervention strategies team grant. Title: Improving cardiovascular health for Canadians living with spinal cord injury: effects of exercise and targeted education. Period: Dec. 2011-Nov. 2016. ROLE: PI

15. Craig H. Neilsen Foundation/Christopher and Dana Reeve Foundation. Title: Recovery of cardiovascular function with epidural stimulation after human spinal cord injury. Period: January 2015-December 2017. PI: Dr. Susan Harkema ROLE: Co-Investigator

16. Canadian Institutes of Health Research (CIHR) / Operating grant. Title: Beyond VO2peak: Understanding exercise-induced changes in cardiovascular function after stroke. Period: 2011-2015. PI: Dr. J. Eng ROLE: Co-Investigator

17. International Spinal Research Trust / Operating grant. Title: Peripheral Sympathetic and sensory plasticity in bladder and bowel circuitry in chronic spinal cord injury. Period: Jan. 2011-Aug. 2014. PI: Dr. M. Ramer ROLE: Co-Investigator

18. Rick Hansen Institute Start Up Funds. Title: Rick Hansen Institute Start-Up Funds. Period: March 2007 – March 2020. ROLE: PI

OTHER

Coloplast and WellSpect

162Intravesicular Lidocaine: Pharmacodynamics and Effects on Autonomic Dysreflexia PreventionFriday, May 04, 2018 09:15 AM - 10:15 AM

Learning Objectives:Identify role of intravesicular lidocaine in pretreatment of SCI patients at risk for autonomic dysreflexia.

Participants:Solinsky RSpaulding Rehabilitation Hospital , Boston , MA, United statesRyan Solinsky, MDSpaulding Rehabilitation Hospital Bio:Ryan Solinsky, MD, is a clinician-scientist at Spaulding Rehabilitation Hospital and Harvard Medical School. As a spinal cord injury medicine provider, he treats patients at Spaulding Hospital and Beth Israel Deaconess Medical Center in Boston, Massachusetts. He received Bachelor’s degrees in Biomedical Engineering and Studio Art at the University of Minnesota prior to earning his medical degree at Case Western Reserve University. He completed his Rehabilitation Medicine residency at the University of Washington followed by a Spinal Cord Injury Medicine fellowship at Kessler Institute for Rehabilitation. His research centers on understanding and reducing the autonomic complications of spinal cord injury. Education:University of Minnesota (Minneapolis, WA), BS 2002-2008 Biomedical Engineering, Studio Art

Case Western Reserve University School of Medicine (Cleveland, OH), MD 2008-2012 Medicine University of Washington (Seattle, WA) 2012-2016 PM&R Kessler Institute for Rehabilitation/Rutgers New Jersey Medical School (West Orange, NJ) 2016-2017, Spinal Cord Injury Medicine Fellowship This author has no relevant disclosures.

163Targeting movement strategies to reduce impingement of the rotator cuff during overhead reaching in individuals with spinal cord injuryFriday, May 04, 2018 09:15 AM - 10:15 AMLearning Objectives:1. Identify movements of the shoulder that are associated with reduced risk to the supraspinatus and infraspinatus during an overhead reaching task.

Participants:Cloud B, Madansingh S, Fortune E, Morrow M, Zhao KMayo Clinic , Rochester , Minnesota, USABeth Cloud, PT, DPT, PhDMayo Clinic Bio:Beth Cloud is an assistant professor in the Physical Therapy Doctoral Program at Mayo Clinic. She is a 2010 graduate of the same program. She completed a Ph.D. in Clinical and Translational

Science from the Mayo Clinic Graduate School of Biomedical Sciences in 2015 with a thesis evaluating spine and shoulder motion during manual wheelchair propulsion. Dr. Cloud's primary research interests are the evaluation of upper limb biomechanics and the characterization and treatment of secondary conditions following neurological injury. She works collaboratively with a multidisciplinary team in the Rehabilitation Medicine Research Center to execute this research agenda. Dr. Cloud's teaching interests include anatomy, neuroscience, neurorehabilitation, biomechanics, and research topics. Clinically she works in neurorehabilitaiton, primarily treating patients in an acute setting. Education:Anatomy Training Program, Anatomical Society & American Association of Anatomists; Certificate (2014-2017)

Mayo Clinic Graduate School of Biomedical Sciences, Rochester, MN; Ph.D., Clinical and Translational Science (2010-2015)

Mayo Clinic School of Health Sciences, Rochester, MN; Doctor of Physical Therapy (2007-2010)

Augustana College, Rock Island, IL; B.A., Psychology & Biology (2003-2007) This author has the following disclosures:

Research SupportDr. Cloud is employed my Mayo Clinic as a Physical Therapy Educator and Assistant Professor and receives a salary. The work being presented is supported by the Mayo Clinic Rehabilitation Medicine Research Center, on behalf of the Craig H. Neilsen Fund for Spinal Cord Injury Care and Research Honoring Robert D. Brown Jr., M.D.Stefan Madansingh, PhDMayo Clinic This author has the following disclosures:

Research Support Consultant

Dr. Madansingh is employed my Mayo Clinic as a Research Fellow and receives a salary. He is employed as a consultant to iShoe, Inc., a medical device small-business focused upon falls risk management in elderly populations. The work being presented is supported by the Mayo Clinic Rehabilitation Medicine Research Center, on behalf of the Craig H. Neilsen Fund for Spinal Cord Injury Care and Research Honoring Robert D. Brown Jr., M.D.Emma Fortune, PhDMayo Clinic This author has the following disclosures:

Research SupportDr. Fortune is employed by Mayo Clinic Department of Health Sciences Research as an Assistant Professor and a Research Associate and receives a salary. The work being presented is supported by the Mayo Clinic Rehabilitation Medicine Research Center, on behalf of the Craig H. Neilsen Fund for Spinal Cord Injury Care and Research Honoring Robert D. Brown Jr., M.D.

Melissa Morrow, PhDMayo Clinic This author has the following disclosures:

Research SupportDr. Morrow is employed by Mayo Clinic Department of Health Sciences Research as an Associate Consultant I and receives a salary. The work being presented is supported by the Mayo Clinic Rehabilitation Medicine Research Center, on behalf of the Craig H. Neilsen Fund for Spinal Cord Injury Care and Research Honoring Robert D. Brown Jr., M.D.Kristin Zhao, PhDMayo Clinic This author has the following disclosures:

Research SupportDr. Zhao is employed by Mayo Clinic Department of Physical Medicine and Rehabilitation as an Associate Consultant II and receives a salary. The work being presented is supported by the Mayo Clinic Rehabilitation Medicine Research Center, on behalf of the Craig H. Neilsen Fund for Spinal Cord Injury Care and Research Honoring Robert D. Brown Jr., M.D.

164Assessing patterns of pressure injury development in patients with Spinal Cord Injury (SCI) with Lower Motor Neuron (LMN) and Upper Motor Neuron (UMN) lesions: A Case ReportFriday, May 04, 2018 09:15 AM - 10:15 AMLearning Objectives:To determine whether patients with SCI with LMN lesions are more likely to develop more severe pressure injuries, needing more specialized treatments for wound closure, compared with patients with UMN lesions.

Participants:1Morgan M, 1Catania Q, 2Martin R, 3Dean J1Kennedy Krieger Institute , Baltimore , MD, 21230; 2Kennedy Krieger Institute; The Johns Hopkins University School of Medicine , Baltimore , MD, USA; 3Kennedy Krieger Institute; Johns Hopkins Department of Rehabilitation , Baltimore , MD, 21230Marjorie Morgan, BS, PTAKennedy Krieger Institute Bio:Marjorie Morgan, PTA is currently a physical therapy assistant at Kennedy Krieger Institute, International Center for Spinal Cord Injury. Marjorie has had extensive experience working with patients with Cerebral Palsy and brain injury through Kennedy Krieger’s Specialized Transitional Program and patient’s with limb deformities at International Center for Limb and Lengthening. In 2008, she transitioned to the International Center for Spinal Cord Injury, where she currently treats patients with SCI. Education:Baltimore City Community College, Baltimore, MD A.A. Degree, Physical Therapy Assistant,

1995

Towson University, Baltimore, MD B.S. Degree, Business Administration, 1990 This author has no relevant disclosures.Quyen Catania, PT, DPT, CWSKennedy Krieger Institute Bio:Quyen Catania, PT, DPT, CWS graduated from University of Notre Dame with a Bachelor of Science and Washington University in St. Louis with her Doctorate in Physical Therapy. In 2015, she obtained her Certified Wound Specialist Certification. She is currently a physical therapist level III at Kennedy Krieger Institute, International Center for Spinal Cord Injury. Education:Doctor of Physical Therapy, May 2012 • Washington University in St. Louis

Bachelor of Science, May 2009 • University of Notre Dame This author has no relevant disclosures.Rebecca Martin, OTR/L, OTD, CPAMKennedy Krieger Institute; The Johns Hopkins University School of Medicine This author has no relevant disclosures.Janet Dean, MS, RN, CRRN, CRNPKennedy Krieger Institute; Johns Hopkins Department of Rehabilitation This author has no relevant disclosures.

165Long Term Experience with Diaphragm Pacing for Traumatic Spinal Cord Injury: Early Implantation Post Injury is More Beneficial Friday, May 04, 2018 09:15 AM - 10:15 AMLearning Objectives:Discuss Diaphragm Pacing in traumatic SCI and identify which sub populations benefit most from DP therapy.

Participants:Onders R, Elmo MUniversity Hospitals Cleveland Medical Center , Cleveland , Ohio, USARaymond Onders, MDUniversity Hospitals Cleveland Medical Center Bio:Raymond P. Onders MD is Professor of Surgery at Case Western Reserve University School of Medicine and Chief of Surgery at University Hospitals Cleveland Medical Center. Over the last 20 years, he has focused his research efforts on ways to help people with spinal cord injuries and

other patients breathe naturally using their own diaphragm. One of his first research subjects was the late Christopher Reeve (Superman). He has authored over 100 publications and book chapters on these subjects. He focuses now on using diaphragm pacing to shorten mechanical ventilation on all intensive care unit patients.

He has multiple patents in this technology and is honored with the Walter and Margaret Remen Chair of Surgical Innovation.

He is active in many surgical organizations and has been President of Midwest Surgical Association and Cleveland Surgical along with being on the Board of SAGES. He earned his M.D. at Northeastern Ohio Universities College of Medicine in 1988, where he recently received the Distinguished Alumni Award, its highest honor, for his work in advancing medicine. Dr. Onders joined the University Hospitals staff in 1997, following his service with the military where he was a Major in the United States Air Force. Among his multiple other honors, include the Maurice Saltzman Award presented on behalf of the Mount Sinai Health Care Foundation, Crain’s Cleveland Business 2008 Health Care Heroes for Advancements in Health, the Rescuer of Humanity Award presented by Values in Action Foundation, and the ALS Association’s Bob Feller Legacy Award in 2013 for his work with Lou Gehrig’s disease. Education:EDUCATION:

General Surgery Residency: Case Western Reserve University Surgical Residency Program 1988-1993 2074 Abington Road Cleveland, Ohio 44106-5000 Residency Review Committee 1990-1993

Medical School: Northeastern Ohio Universities College of Medicine 1984-1988 Rootstown, Ohio 44272 M.D. awarded 5/28/88 Alpha Omega Alpha Biochemistry Teaching Fellow Air Force Health Professions Scholarship

Undergraduate Education: Kent State University 1982-1984 Kent, Ohio 44242 Bachelor of Science Salutatorian Summa Cum Laude Varsity Track and Field This author has the following disclosures:

Research Support Shareholder Other (see below)

Dr. Onders with Case Western Reserve University and University Hospitals Cleveland Medical Center founded Synapse Biomedical and our shareholders. Dr. Onders is also Chief Medical Officer and Board memberMaryJo Elmo, ACNPUniversity Hospitals Cleveland Medical Center This author has no relevant disclosures.

166Pilot Test of a SCI Virtual Coach to Improve Skin CareFriday, May 04, 2018 09:15 AM - 10:15 AMLearning Objectives:The objective of this session is to increase understanding of how virtual coaches can be used to promote health behaviors in persons with SCI.

Participants:1Latham N, 2Houlihan B, 3Ellis T, 4Trinh H, 4Shamekhi A, 3DeAngelis T, 3Ni P, 5Everhart Skeels S, 3Zazulu J, 3Sullivan N, 3Gross L, 6Bickmore T1Brigham and Women's Hosptial , Boston , MA, USA; 2Spaulding New England Regional Sci Center (Snerscic), Mgh Institute of Health Professions , Boston , MA, USA; 3Boston University , Boston , MA, USA; 4Northeastern University , Boston , MA, USA; 5Spaulding New England Regional Sci Center, Mgh Institute of Health Professions , Boston , MA, USA; 6Northeastern , Boston , MA, USANancy Latham, PhD PTBrigham and Women's Hosptial Bio:Nancy Latham PhD PT is an Associate Epidemiologist at Brigham and Women's Hospital in Boston MA. She is a physical therapist and clinical epidemiologist whose research has focused on developing and evaluating innovative interventions to improve health and function in persons with disabling conditions. She completed a PhD at the University of Auckland and a post-doctoral fellowship in Health Services Research at Boston University. She has been the principal investigator or co-investigator on randomized controlled trials including the HIP Rehab - Boston Hip Fracture trial (n=232) that found that a home-based exercise program was effective in improving function in older people post-hip fracture and the FITNESS trial of fall prevention in frail older adults (n=240). She has conducted systematic reviews and analyses of longitudinal cohort studies that explored the effectiveness of interventions to improve function in people with different conditions, and explored the complex social, environmental, psychological and physical factors that contribute to changes in function and disability. She was the PI a Craig H. Neilsen Foundation grant to develop and field test the first virtual coach for persons with spinal cord injury. Education:University of Toronto (Toronto, Ontario) BS (Physical Therapy) 1988-1992

McGill University (Montreal, PQ) MS (Rehabilitation Science) 1993-1995

University of Auckland (Auckland, New Zealand) PhD (Medicine - Clinical Epidemiology) 1998-2002

Boston University (Boston, MA) Postdoctoral Fellowship (Health Services Research) 2002-2003This author has no relevant disclosures.Bethlyn Houlihan, MSW MPHSpaulding New England Regional Sci Center (Snerscic), Mgh Institute of Health Professions This author has no relevant disclosures.Terry Ellis, PhD PT NCSBoston University This author has no relevant disclosures.Ha Trinh, PhDNortheastern University This author has no relevant disclosures.Ameneh Shamekhi, BSNortheastern University This author has no relevant disclosures.Tamara DeAngelis, DPT GCSBoston University This author has no relevant disclosures.Pengsheng Ni, MD MPHBoston University This author has no relevant disclosures.Sarah Everhart Skeels, MPHSpaulding New England Regional Sci Center, Mgh Institute of Health Professions This author has no relevant disclosures.Judi Zazulu, OTRBoston University This author has no relevant disclosures.Nicole Sullivan, OT/SBoston University This author has no relevant disclosures.Libby Gross, OT/SBoston University This author has no relevant disclosures.Timothy Bickmore, PhDNortheastern This author has no relevant disclosures.

167Identifying and overcoming barriers to successful on-time completion of clinical trials in SCI: protocol design and recruitment perspectives

Friday, May 04, 2018 10:30 AM - 11:30 AMLearning Objectives:Educational Objectives: 3 On completion of this course, participants will be able to: • Identify barriers related to protocol design and recruitment for SCI clinical trials. • Consider possible options to overcome identified barriers. • Access tools to improve protocol design and recruitment

Participants:1Blight A, 2Jones L, 3Hsieh J1Acorda Therapeutics (Ret) , New York , New york, USA; 2Craig Neilsen Foundation , Encino , California, USA; 3Wings for Life , Toronto , Ontario, CanadaAndy Blight, PhDAcorda Therapeutics (Ret) Bio:Andrew R. Blight, Ph.D. recently retired from the role of Chief Scientific Officer of Acorda Therapeutics, which he had held since 2004. He received bachelors and doctoral degrees from the University of Bristol (UK) and completed postdoctoral studies at New York University and the Max Planck Institute for Brain research in Frankfurt. His professional career began in academia, as a Research Assistant Professor in the Department of Neurosurgery at NYU Medical Center. He subsequently moved to the School of Veterinary Medicine at Purdue University as Associate Professor of Anatomy and then to Division of Neurosurgery at the University of North Carolina, Chapel Hill, where he was Professor and Director of the Research Laboratory from 1992 to 1998. His research concentrated on the pathophysiology of spinal cord injury (SCI) and potential therapeutic approaches, with particular interest in the role of inflammation in acute tissue damage and the contribution of demyelination to long-term functional deficits. His work on the therapeutic application of 4-aminopryidine (4-AP) in SCI began with in vitro experiments and moved on through animal studies, naturally occurring SCI in dogs and human subjects. This experience led him to join the recently formed Acorda Therapeutics Inc., in 1998, as head of research and development. Acorda carried 4-AP (now known by its nonproprietary name of dalfampridine) through clinical studies in chronic SCI, multiple sclerosis and stroke. The drug was approved by the FDA in 2010, for improvement of walking in people with multiple sclerosis. Dr. Blight is co-chair of SCOPE, a member of the editorial board of the Journal of Neurotrauma and past treasurer and vice president of the National Neurotrauma Society. Education:PhD, University of Bristol, UKThis author has no relevant disclosures.Linda Jones, PT, MScCraig Neilsen Foundation Bio:A physical therapist by training, I have an established career in spinal cord injury (SCI) research, in clinical trial management and as a Program Officer managing a translation research portfolio. Throughout my career I have had an interest in outcomes research. My master’s thesis, “Reliability and Validity of the Acute Care Index of Function in the Critically Ill”, established psychometrics for a functional outcome measure in the intensive care unit. After leaving clinical

practice, I managed the first two cell based SCI studies, developing the skills to oversee large and complex projects. I also learned about the challenges and importance of the appropriate use of functional outcomes in clinical trials and sit on a number of committees and working groups addressing these challenges.

Currently, I manage a translation research portfolio at the Craig H. Neilsen Foundation. In this position, I have the opportunity to see the latest pre-clinical and clinical research directions, identify gaps in the field and consider ways in which they can be addressed.

My current focus through the Spinal Cord Outcomes Partnership Endeavor (SCOPE), Spinal Cord Injury Trials Toolkit (SCITT) and Spinal Trials Understanding Design and Implementation (STUDI) is in clinical trial design, outcomes and execution. Through my doctoral dissertation work, I am exploring methods to support the analysis of multiple large spinal cord injury databases. Education:PT MScThis author has no relevant disclosures.Jane Hsieh, MScWings for Life Bio:After receiving my graduate neurophysiology training at McGill University, I have spent more than 30 years in spinal cord injury (SCI) research. Throughout my career, I have been involved with SCI research in academia, industry, non-profit organizations and in my own consulting business. Currently, my main focus is acting as the Executive Director of the Accelerated Translational Program of Wings for Life. Managing this portfolio requires up to date knowledge of SCI clinical trials from both scientific and operational perspectives. Overseeing two large multi-centre drug trials in chronic SCI and many smaller complex multi-centre trials in acute, chronic, drug, device, and biologic therapeutics has afforded me extensive experience in all aspects and types of clinical trials. I bring this experience to my participation in Spinal Cord Outcomes Partnership Endeavor (SCOPE), Spinal Cord Injury Trials Toolkit (SCITT) and Spinal Trials Understanding Design and Implementation (STUDI).Education:MScThis author has no relevant disclosures.

168Considering Neurorehabilitation with Emerging Therapies: How does training effect recovery? Friday, May 04, 2018 10:30 AM - 11:30 AMLearning Objectives:1. Learner will review existing SCI recovery programs spanning from community facilities to nationwide network organizations. 2. Learner will understand the differences in approach from each setting.

3. Learner will understand different rehab settings applied to interventional studies for paralysis, such as neuromodulation.

Participants:1Gill M, 1Linde M, 2Joyce M, 3Brennan M1Mayo Clinic , Rochester , MN, USA; 2Craig Hospital , Englewood , CO, USA; 3Exerciseabilities, Inc. , Rochester , MN, USAMegan Gill, DPTMayo Clinic Bio:Megan Gill, PT, DPT, NCS, is a Rochester, MN native who received her Bachelor of Science degree from Minnesota State University, Mankato, in 2001. She continued her professional career working as a research assistant at Mayo Clinic’s Sports Medicine Center under a grant provided by USA hockey, synthesizing the world literature in ice hockey injuries. Megan received her master’s in physical therapy from Mayo Clinic College of Medicine in 2004 and later pursued her doctorate in physical therapy from The College of St. Scholastica in 2011. In 2010, Megan was designated the Clinical Lead Physical Therapist for Mayo Clinic’s SCI program. Education:Minnesota State University, Mankato, Mankato, Minnesota - BS 1997 - 2001 Mayo Clinic School of Health-Related Sciences, Mayo Clinic College of Medicine, Rochester, Minnesota - MPT 2002 - 2004 College of St. Scholastica, Duluth, Minnesota - DPT 2009 - 2011 This author has the following disclosures:

Other (see below)Ms. Gill is employed by Mayo Clinic Department of Physical Medicine and Rehabilitation as a Physical Therapist and receives a salary.Margaux Linde, Mayo Clinic Bio:Margaux Linde has been working as an exercise specialist for 11 years in a variety of areas. For the last 8 years she has specialized in post rehab fitness, and in most recent years has focused on developing and managing an intensive neurological recovery program in Rochester, MN. Margaux has a B.S. in Exercise Science from Minnesota State University, Mankato. She is a National Academy of Sports Medicine certified personal trainer since 2005 and carries certifications from the NeuroRecovery Network and through Neruro RTI in Locomotor Training and the Neuromuscular Recovery Scale. Margaux is also certified in Pilates and Sport Yoga through the National Exercise and Sport Trainer's Association and stays active in fitness in her spare time. Margaux is now working as a kinesiologist for the Assistive Restorative Technology Lab under the direction of Dr. Kristin Zhao, here at Mayo Clinic. Margaux was asked to join the epidural stimulation research team as a kinesiologist because of her expertise in locomotor training and the neuromuscular recovery scale.Education:2003-2005 Minnesota State University, Mankato, MN • Bachelor of Science, Human Performance/Physical Education

This author has the following disclosures: Other (see below)

Ms. Linde is employed by Mayo Clinic Department of Physical Medicine as a research kinesiologiest and receives a salary.Meghan Joyce, DPTCraig Hospital Bio:Meghan Joyce, DPT, NCS has been the Clinical Supervisor of NeuroRecovery Network at Craig Hospital in Englewood, CO since 2012. Prior to her supervisor role, she was a staff physical therapist at Craig Hospital from 2010-2012.Education:PROFESSIONAL LICENSES, MEMBERSHIPS, CERTIFICATIONS • Colorado Physical Therapy License 2010-Present • American Physical Therapy Association 2007-Present • Academy of Neurologic Physical Therapy Section Member 2007-Present • Spinal Cord Injury SIG • Colorado Acute Care/Rehabilitation SIG • Academy of Spinal Cord Injury Professionals 2010-Present • Neurologic Clinical Specialist (NCS) July 2016 This author has the following disclosures:

Other (see below)Ms. Joyce is employed by Craig Hospital as a supervisor for the NeuroRecovery Network. Since 2014, this project was funded by the Christopher & Dana Reeve Foundation. It was supported, in part, by cooperative agreement numbers 90PR3001 and 90PR3002, from the U.S. Administration for Community Living, Department of Health and Human Services, Washington, D.C. 20201. Grantees undertaking projects under government sponsorship are encouraged to express freely their findings and conclusions. Points of view or opinions do not, therefore, necessarily represent official Administration for Community Living policy.

Prior to 2014, this project was funded by the Christopher & Dana Reeve Foundation through various cooperative agreements with the Centers for Disease Control and Prevention (cooperative agreement numbers 1U59DD000838, 1U59DD000338, and U10/CCU220379). Melanie Brennan, DPTExerciseabilities, Inc. Bio:Melanie Brennan, PT, DPT is Founder and CEO at Exercisabilities, a nonprofit neurologic recovery center in Rochester, MN. She founded Exercisabilities in 2011 to provide community based rehabilitation and wellness opportunities for people with neurologic injuries in southeast Minnesota. Melanie is a graduate of the doctor of physical therapy program at The College of St. Scholastica in Duluth, MN. Her 20 years of experience includes 3 years working in the Fairview Southdale Hospital Acute Stroke Program and 11 years as a spinal cord injury team member at Mayo Clinic Rochester Acute Rehabilitation Unit. In her current role as a clinic administrator, Dr. Brennan strives to inspire her staff of therapists and exercise specialists to create a long-term road map to recovery and wellness for each client to support their life long journey toward optimal health.

Education:Doctor in Physical Therapy The College of St Scholastica, Duluth, Minnesota December 2008 GPA: 4.0

Master of Arts in Physical Therapy February 1998 The College of St Scholastica, Duluth, Minnesota ♦ Cumulative GPA: 3.8

Bachelor of Arts Degree, Health Sciences May 1996 The College of St Scholastica, Duluth, Minnesota ♦ Cumulative GPA: 3.9 ♦ Institutional Honors: Summa Cum Laude

Post-Secondary Option Education Sept. 1992 - May 1993 Rochester Community College, Rochester, Minnesota

High School Degree May 1993 Byron High School Byron, Minnesota ♦ Graduated with Highest Honors This author has the following disclosures:

Other (see below)Melanie Brennan, PT, DPT is Founder and CEO at Exercisabilities, a nonprofit neurologic recovery center in Rochester, MN.

169The EEG-controlled noninvasive MoreGrasp neuroprosthesis - decoding of multiple natural single limb movements and multipad-electrodes for closed-loop grasp pattern controlFriday, May 04, 2018 10:30 AM - 11:30 AMLearning Objectives:Participants will learn the current challenges of noninvasive grasp neuroprostheses and how to overcome them with array stimulation electrodes and EEG-based brain-computer interfaces based on the classification of single limb movements.

Participants:1Rupp R, 1Schneiders M, 1Hessing B, 2Murray-Smith R, 2Ramsay A, 3Luzhnica G, 3Veas E, 4Schwarz A, 4Pereira J, 4Ofner P, 4Pinegger A, 4Mueller-Putz G1Heidelberg University Hospital - Spinal Cord Injury Center , Heidelberg , BW, Germany; 2University of Glasgow - School of Computing Science , Glasgow , Scotland, United kingdom; 3Know Center , Graz , , Austria; 4Graz University of Technology - Institute of Neural Engineering , Graz , , AustriaRuediger Rupp, Dr.-Ing.Heidelberg University Hospital - Spinal Cord Injury Center

Bio:Ruediger Rupp received the Dipl.-Ing. degree in electrical engineering with focus on biomedical engineering and his Ph.D. degree from the Technical University of Karlsruhe, Germany, in 1994 and 2008, respectively. After working at the Institute for Biomedical Engineering and Biocybernetics (Prof. G. Vossius) until 1996, since 1997 he is with the Spinal Cord Injury Center (Head: Prof. N. Weidner) of Heidelberg University Hospital, Germany, where he holds the position as the head of the Experimental Neurorehabilitation group. His main research interests are in the field of rehabilitation engineering for spinal cord injured patients. This includes neuroprosthetics mainly of the upper extremity, man-machine interfaces, gait analysis, development and clinical validation of novel methods and devices for locomotion therapy and realization of software projects for standardized documentation of rehabilitation outcome. He is author of more than 200 journal, book and conference abstracts and holds two patents. He has been awarded several times for his work and is a member of IEEE, IFESS, VDE, DMGP, DGOOC, ISCoS and ASIA.

Education:1989 - 1994 Electrical engineering, Technical University of Karlsruhe, GermanyThis author has the following disclosures:

Research SupportFinancial Support from the EU ICT Programme Project H2020-643955 MoreGrasp, Role: Co-PIMatthias Schneiders, B.Sc.Heidelberg University Hospital - Spinal Cord Injury Center This author has the following disclosures:

Research SupportFinancial Support from the EU ICT Programme Project H2020-643955 MoreGrasp, Role: EmployeeBjoern Hessing, Heidelberg University Hospital - Spinal Cord Injury Center This author has the following disclosures:

Research SupportFinancial Support from the EU ICT Programme Project H2020-643955 MoreGrasp, Role: EmployeeRoderick Murray-Smith, Prof. PhDUniversity of Glasgow - School of Computing Science This author has the following disclosures:

Research SupportFinancial Support from the EU ICT Programme Project H2020-643955 MoreGrasp, Role: Co-PIAndrew Ramsay, University of Glasgow - School of Computing Science This author has the following disclosures:

Research Support

Financial Support from the EU ICT Programme Project H2020-643955 MoreGrasp, Role: EmployeeGranit Luzhnica, Know Center This author has the following disclosures:

Research SupportFinancial Support from the EU ICT Programme Project H2020-643955 MoreGrasp, Role: EmployeeEduardo Veas, PhDKnow Center This author has the following disclosures:

Research SupportFinancial Support from the EU ICT Programme Project H2020-643955 MoreGrasp, Role: Co-PIAndreas Schwarz, Dipl.-Ing.Graz University of Technology - Institute of Neural Engineering This author has the following disclosures:

Research SupportFinancial Support from the EU ICT Programme Project H2020-643955 MoreGrasp, Role: EmployeeJoana Pereira, Graz University of Technology - Institute of Neural Engineering This author has the following disclosures:

Research SupportFinancial Support from the EU ICT Programme Project H2020-643955 MoreGrasp, Role: EmployeePatrick Ofner, Graz University of Technology - Institute of Neural Engineering This author has the following disclosures:

Research SupportFinancial Support from the EU ICT Programme Project H2020-643955 MoreGrasp, Role: EmployeeAndreas Pinegger, Dipl.-Ing.Graz University of Technology - Institute of Neural Engineering This author has the following disclosures:

Research SupportFinancial Support from the EU ICT Programme Project H2020-643955 MoreGrasp, Role: EmployeeGernot Mueller-Putz, Univ.-Prof. Dr.-techn.Graz University of Technology - Institute of Neural Engineering This author has the following disclosures:

Research Support

Financial Support from the EU ICT Programme Project H2020-643955 MoreGrasp, Role: PI

170Impact of Barriers and Facilitators on Travel Needs Satisfaction of People with SCIFriday, May 04, 2018 10:30 AM - 11:30 AMLearning Objectives:Explain the impact of travel barriers and facilitators on the psychological needs of individuals living with SCI.

Participants:1Cole S, 1Holback N, 1Kang S, 2Whiteneck G1Indiana University , Bloomington , IN, USA; 2Craig Hospital , Englewood , CO, USAShu Cole, Ph.D.Indiana University Bio:Shu Cole, Ph.D, is currently an Associate Professor in the Department of Recreation, Park and Tourism Studies of Indiana University School of Public Health – Bloomington. Her research interest is in travel services marketing with a focus on the travel experience of people with mobility impairment. Her current research projects include 1) understanding the travel barriers experienced by people with spinal cord injury; 2) identifying innovative solutions to facilitate accessibility of airports; and 3) developing an innovative system for lodging facilities to provide accessibility-related information for guests with spinal cord injury.

Shu Cole has published widely in refereed journals and presented at numerous national and international conferences. She has co-authored two book chapters on inclusive travel and tourism, and currently serves on the editorial board of several peer-reviewed journals including the Journal of Travel Research. She also serves on the Research Committee of the Academy of Spinal Cord Injury Professionals, and is the research co-chair of the National Recreation and Parks Association’s Research Sessions. Education:Nankai University (Tianjin, China): BA, 1984-1988, English

Texas A&M University (College Station, TX): MA, 1991-1993, Philosophy

Texas A&M University (College Station, TX): Ph.D., 1993-1998, Recreation, Parks, & Tourism SciencesThis author has the following disclosures:

Research SupportPI of a projected funded by Craig H. Neilsen (#321788)Noah Holback, Indiana University This author has no relevant disclosures.

Sangguk Kang, Indiana University This author has no relevant disclosures.Gale Whiteneck, PhDCraig Hospital This author has no relevant disclosures.

171Electrical Nerve Block for Control of Pain and Spasticity in Spinal Cord InjuryFriday, May 04, 2018 10:30 AM - 11:30 AMLearning Objectives:1. Become aware of the new field of electrical nerve conduction block. 2. Understand the current status of research in the application of transcutaneous direct current block and the potential applications for pain and spasticity relief in spinal cord injury.

Participants:1Kilgore K, 2Bhadra N, 2Vrabec T, 2Bhadra N1Metrohealth Medical Center , Cleveland , OH, USA; 2Case Western Reserve University , Cleveland , OH, United statesKevin Kilgore, PhDMetrohealth Medical Center Bio:Kevin L. Kilgore, Ph.D., received the BS degree in Biomedical Engineering from the University of Iowa, Iowa City, in 1983, and the MS and Ph.D. degrees in Biomedical Engineering from Case Western Reserve University, Cleveland, in 1987 and 1991. He is currently Professor, Department of Orthopaedics at MetroHealth Medical Center and School of Medicine, Case Western Reserve University. He is also a Biomedical Engineer in the Research Service of the Louis Stokes Cleveland Veterans Affairs Medical Center and is an Associate Director in the Cleveland Functional Electrical Stimulation Center. His research interests are in the clinical applications of functional electrical stimulation to provide hand and arm function for individuals with paralysis, and in the application of electrical currents to control unwanted neural activity.Education:University of Iowa (Iowa City, IA), BS 1979-1983 Biomedical Engineering

Case Western Reserve University (Cleveland, OH), MS 1983-1987 Biomedical Engineering

Case Western Reserve University (Cleveland, OH), PhD 1987-1991 Biomedical EngineeringThis author has the following disclosures:

Research Support Other (see below)

Equity ownership in Neuros Medical, Inc. Sponsored Research Agreement support from Halyard Health, Inc.

Narendra Bhadra, MD, PhDCase Western Reserve University This author has the following disclosures:

Research SupportSponsored Research Agreement support from Halyard Health, Inc.Tina Vrabec, PhDCase Western Reserve University This author has the following disclosures:

Research SupportSponsored Research Agreement support from Halyard Health, Inc.Niloy Bhadra, MD, PhDCase Western Reserve University This author has the following disclosures:

Research Support Other (see below)

Equity ownership in Neuros Medical, Inc. Sponsored Research Agreement support from Halyard Health, Inc.

172A Novel Approach to Patient Education: Creating a Mobile Web Application for Patients with Spinal Cord InjuryFriday, May 04, 2018 10:30 AM - 11:30 AMLearning Objectives:To create a comprehensive and easy to use educational web-based mobile application (app) for patients with SCI.

Participants:Mekki M, Marzloff G, Huang V, Bryce TMount Sinai Hospital, Icahn School of Medicine , New York , NY, USAMarwa Mekki, MDMount Sinai Hospital, Icahn School of Medicine Bio:Marwa Mekki obtained her medical degree at the University of Illinois in Chicago and completed her residency training in Physical Medicine and Rehabilitation at Mount Sinai Hospital in New York. She is currently the Spinal Cord Injury Medicine Fellow at Mount Sinai.Education:Northwestern University (Evanston, IL) BA 2004-2008, Sociology University of Illinois at Chicago College of Medicine (Chicago, IL), MD 2009-2013, Medicine Jacobi Medical Center (Bronx, NY), 2013-2014, Internal Medicine Internship Mount Sinai Hospital, Icahn School of Medicine (New York, NY), 2014-2017, Physical Medicine and Rehabilitation Mount Sinai Hospital, Icahn School of Medicine (New York, NY), 2017-2018, Spinal Cord Injury Medicine

This author has no relevant disclosures.George Marzloff, MDMount Sinai Hospital, Icahn School of Medicine This author has no relevant disclosures.Vincent Huang, MDMount Sinai Hospital, Icahn School of Medicine This author has no relevant disclosures.Thomas Bryce, MDMount Sinai Hospital, Icahn School of Medicine This author has no relevant disclosures.

173Endogenous Cortisol Delivery Following Spinal Cord Injury: Clinical Implications Friday, May 04, 2018 10:30 AM - 11:30 AMLearning Objectives:Endocrine medicine; acute trauma

Participants:1Clark J, 1Nenke M, 2David S, 1Marshall R, 3Dunlop S, 4Galea M, 1Torpy D1Royal Adelaide Hospital , Adelaide , South aust, Australia; 2University of Adelaide , Adelaide , South aust, Australia; 3University of Western Australia , Perth , Western au, Australia; 4University of Melbourne , Melbourne , Victoria, AustraliaJillian Clark, Ph.D.Royal Adelaide Hospital Bio:Dr Jillian Clark is a Senior Research Fellow, Spinal Services, Royal Adelaide Hospital and Affiliate Professor, School of Medicine, Faculty of Health and Medical Sciences, University of Adelaide, Adelaide, South Australia Education:Doctor of Philosophy (Medicine) This author has no relevant disclosures.Marnie Nenke, MDRoyal Adelaide Hospital This author has no relevant disclosures.Sharkey David, Ph.D.University of Adelaide This author has no relevant disclosures.Ruth Marshall, MDRoyal Adelaide Hospital This author has no relevant disclosures.Sarah Dunlop, Ph.D.University of Western Australia

This author has no relevant disclosures.Mary Galea, Ph.D.University of Melbourne This author has no relevant disclosures.David Torpy, MD, Ph.D.Royal Adelaide Hospital This author has no relevant disclosures.

174Early decompression strategy is effective in thoracolumbar traumatic spinal cord injury with lower grade residual spinal canal compressionFriday, May 04, 2018 10:30 AM - 11:30 AMLearning Objectives:Determine the influence of surgical timing on neurological recovery in relationship with the residual canal compression documented after thoracolumbar traumatic spinal cord injury.

Participants:Goulet J, Mac-Thiong JUniversité De Montréal , Montreal , Quebec, CanadaJulien Goulet, MDUniversité De Montréal Bio:Julien Goulet, MD, is a post-graduate year 4 resident in orthopaedic surgery at the University of Montreal. He is implicated in the Spine and Trauma divisions of the Orthopaedic Research Centre at the Sacré-Coeur Hospital in Montreal. His work on spinal cord injury has been supported by Fonds de recherche du Québec – Santé and Fondation de recherche et d'éducation en orthopédie de Montréal under the mentorship of Dr Jean-Marc Mac-ThiongEducation:Université de Montréal (Montreal, Qc, Canada), MD 2010-2014, Medicine 

Université de Montréal (Montreal, Qc, Canada), Orthopaedic Surgery 2014 - ...  This author has the following disclosures:

Research SupportFonds de Recherche Quebec - Sante Fondation de Recherche et d’Education en Orthopedie de Montreal Jean-Marc Mac-Thiong, MD, PhDUniversité De Montréal Bio:Jean-Marc Mac-Thiong, MD, PhD, is a clinician-scientist practicing as an orthopedic spine surgeon at the Hopital du Sacre-Coeur de Montreal, with a multidisciplinary background in spine surgery (MD, fellowship), biomedical sciences (MSc, PhD), and engineering (BEng). He is an associate professor of surgery and research director of the Orthopedics Division at Université de Montréal. He is Chairman of the Medtronic Research Chair in spinal trauma at Université de

Montréal and in charge of the Rick Hansen Spinal Cord Injury Registry at Hopital du Sacre-Coeur de Montreal. He is Chair of the Spine/Acute care Committee at the American Spinal Injury Association. His research has been supported by the Canadian Funds for Innovation, Natural Sciences and Engineering Research Council of Canada, Department of the US Army, Fonds de recherche du Québec – Santé, Fonds de recherche du Québec – Nature et technologies, and Scoliosis Research Society. He has focused his research on acute predictors of the outcome after a traumatic spinal cord injury, and on the biomechanical and experimental characterization of traumatic spinal cord injury. Education:École Polytechnique de Montréal (Montreal, Qc, Canada), B.Eng. 1997 Mechanical Engineering 

Université de Montréal (Montreal, Qc, Canada), M.S. 2001 Biomedical Sciences 

Université de Montréal (Montreal, Qc, Canada), MD 2002 Medicine 

Université de Montréal (Montreal, Qc, Canada ), Residendy 2007 Orthopaedic Surgery 

Université de Montréal (Montreal, Qc, Canada), Ph.D. 2008 Biomedical Sciences 

Twin Cities Spine Center (Minneapolis, MN), Fellowship 2008 Spine Surgery This author has the following disclosures:

Research SupportFonds de Recherche Quebec - Sante Fondation de Recherche et d’Education en Orthopedie de Montreal

175State Legislation to Fund Post-Acute Rehabilitation – A Utah ExperienceFriday, May 04, 2018 10:30 AM - 11:30 AMLearning Objectives:At the conclusion of the course, participants will be able to: 1. Describe an example of successful legislation on a state level to provide post-acute rehabilitative services to those with inadequate resources. 2. Discuss the many steps and critical aspects required to pass legislation 3. Understand the importance of learning to communicate effectively and purposely with lawmakers to assist in forming public policy and active legislation.

Participants:1Hull D, 2Lloyd D, 1Black J1Neuroworx , Sandy , UT, USA; 2Wcf Insurance , Sandy , UT, USADale Hull, MD, MPANeuroworx Bio:Dr. Dale Hull is a graduate of the University of Utah School of Medicine in 1985. This was

followed by a residency in Obstetrics and Gynecology at the University of Utah Medical Center. He was in private practice from 1989 to 1999 in the south portion of the Salt Lake City metropolitan area.

In 1999, he experienced a spinal cord injury resulting in teraplegic paralysis. The next two and half years were primarily spent with outpatient rehabilitation efforts working with physical therapist Jan Black. Unable to return to active practice, Hull and Black teamed up to co-found Neuroworx, a not-for-profit, innovative, community-based, outpatient physical and occupational therapy clinic in 2004. The facility provides specialized and focused therapy for adults and children experiencing paralysis due to spinal cord injuries, brain injuries, stroke, cerebral palsy, and similar neurological conditions. Dr. Hull currently serves as Executive Director.

Dr. Hull completed a Master of Public Administration degree in 2012 through Brigham Young University. He is the Past President of the University of Utah School of Medicine Alumni Association and is a Board Member for the Sandy Area Chamber of Commerce. He is married and has four sons and lives in South Jordan, Utah. Education:Weber State University (Ogden, UT) 1979 BS Zoology

University of Utah School of Medicine (SLC, UT) 1985 MD Medicine

Brigham Young University, Marriott School of Business, Romney Institute (Provo, UT) 2012 Masters of Public Administration This author has the following disclosures:

Other (see below)Neuroworx employeeDennis Lloyd, JD, MBAWcf Insurance Bio:Dennis Lloyd currently serves as Senior Vice President and Chief Legal Counsel for WCF Insurance, a quasi-public corporation insuring approximately 21,000 policyholders and close to 400 employees. Mr. Lloyd has been with WCF since 1981 and has been involved in all aspects of litigation, adjudication, and subrogation, and has been very active in legislative matters affecting workers compensation issues. Prior to joining WCF, he worked as an auditor in the Utah legislative Auditors General’s Office for three years.

Mr. Lloyd is an Adjunct Professor of Family and Preventive Medicine at the University of Utah and serves as the Advisory Board Chair for the Rocky Mountain Center for Occupational and Environmental Health. He is currently the Secretary/Treasurer of the American Association of State Compensation Insurance Funds. His community volunteer involvement includes being a board member for the YMCA of Northern Utah and of Neuroworx.

Mr. Lloyd has been involved in helping to draft many pieces of legislation from 1991 to present including Utah HB400, The SCI/TBI Rehabilitation Fund, which passed into law in 2012.

Education:University of Utah College of Business (SLC, UT) 1976 BFA Political Science

University of Utah Graduate School of Business (SLC, UT) 1978 MBA Business

University of Utah College of Law (SLC, UT) 1979 JD LawThis author has the following disclosures:

Other (see below)Neuroworx Board Member - unpaidJan Black, PT, MSPTNeuroworx Bio:Jan co-founded Neuroworx in June 2004 and serves as the Clinic Director. She graduated from Utah State University in 1989 with a bachelor of science in physical education. She received her Masters of Science degree in physical therapy from the University of the Pacific in 1991. Following graduation, she returned to Utah and began a career as a practicing clinical physical therapist. The majority of her practice has been focused on people with spinal-cord injuries and similar neurological conditions. She has worked in acute-care in-patient rehabilitation, home health care, and outpatient facilities.

Her postgraduate training has included courses in spinal-cord injury, brain injury, and locomotor training. She is a Certified Clinical Instructor Affiliate through the American Physical Therapy Association. She is an educator for the University of Utah Physical Therapy Doctoral Program (DPT) as well as various other universities and colleges across the country with DPT programs.

In addition to traditional land-based therapy, aquatic therapy has been an important part of patient care throughout Jan's career. In 2002, she began a more advanced form of aquatic therapy using highly specialized pools. Applying her clinical experience with this novel equipment has allowed her to provide innovative and very effective care for people with paralysis. Her unique expertise in this area has provided her with opportunities to present aquatic seminars with a neurological focus to various clinics throughout the country.

Jan assisted with the creation, drafting, and eventual passage of Utah House Bill 400 during the 2012 Legislative Session. This bill created a spinal cord and brain injury fund to provide rehabilitative services to affected people in Utah.

Jan is an active member of the American Physical Therapy Association, including the Neurological and Education sections. Her hobbies include running and, most importantly, being a mom. Jan and her husband have five children. Education:Utah State University (Logan, UT) 1989 BS Physical Education

University of the Pacific (Stockton, CA) 1991 MS Physical TherapyThis author has the following disclosures:

Other (see below)

Neuroworx employee