AUTHOR INDEX

June 1, 1994

Amada,Y., 3011

Badger,B., 2934Bally, M. B., 2830Barmada, S., 2908Barr, F. G., 2869Becker,K., 2900Bellahcène,A., 2823Biegel,J. A., 2869Boman, N. L, 2830Bongarzone, I., 2979Borrello, M. G., 2979Brandt,I.,2887Brissinck,J., 2973Brittebo, E. B., 2887Brøgger, A., 2919Bullrich, F., 2873Butti, M. G., 2979

Caldas, C., 3025Castronovo,V., 2823Chen, L-C., 3021Coleman, M. J., 2908Coombes,R. C., 2986Cordon-Cardo, C., 2848Coronelli, S., 2979Croce, C. M., 2873Cullis, P. R., 2830

da Casts, L, 3025Dalbagni, G., 2848Davis, M. A., 2964Davis, R. J., 2869Daynes, R. A., 3054D'Cruz,C. M., 2869Della Ports, 0., 2979Demanet, C., 2973Demant,E. J. F., 2959Deng, 0., 3021Derias,N.W., 2914Dobashi,Y., 2827Dowel. S. P., 2914

Endo, M., 3007Enomoto, M., 3011Enomoto,1., 3049Ensminger, W. D., 2964Ershler, W. B., 3054Esumi,H.,2841

Finger,M. J., 2861Fink, U., 2900Finn, 0. J., 2856Fontenot,J. D., 2856France, J. L, 2969Frith, C. H., 3054Fujita, M., 3049Fukayama, M., 3011Fukushima,S., 2895Fusco, A., 2979

Gaddipati,J. P., 2861Gamble,G. P., 2908Gerald,W., 2837Ghosh,P., 2969Graziano,S. L, 2908Groden, J., 2991Grossman,H. B., 3062Grove, R., 2934Grue,P., 2959

Hagmar, L, 2919

Hall, P. A., 2914Hansen,H. H., 2959Hansteen,I-L., 2919Hasegawa,T., 2895Hayashi,Y., 2865Heidenberg, H. B., 2861

Heim, S., 2919Heitjan, D., 2934Hdgstedt, B., 2919Hosaka,M., 2852Hruban, R. H., 3025Hsiung, Y., 2943Hummel,M., 2873

Ichikawa,H., 2865Igarashi, H., 3034Igari,T.,3011

Ikenaga, M., 2996Imamura, M., 2996Inoue, M., 3049Ishizaki, K@,2996, 3042Iwama,T., 3011

Jannatipour, M., 2943Jensen, P. B., 2959

Kang, Y., 2952Kern, S. E., 3025Khin, S., 2934Kikuchi,H., 2928Kikuchi-Yanoshita, R., 3011Kim, M., 3054Kino, I., 3034Kishida,T., 2852Kitamura, H., 2852Kiyokawa,E., 3034Knudsen, L., 2919Kohman,L J., 2908Koike, M., 3011Komschlies, K. L., 2969Kondo,K., 2852Kondo,S., 2928Kondoh,0., 3049Konishi, M., 3011Konishi, Y., 2895Kotera, Y., 2856Kotoura, Y., 3042Kubota,Y., 2827, 2852Kurisu, W., 3021Kwok,1. T., 2834Kyo, S., 3049

Lacombe,L, 2848Ladanyi,M., 2837Laderoute, K. R., 2845Lambert, B., 2919Lane, D. P., 2914Langmuir, V. K., 2845Lapenson, D. P., 2878Latif, F., 2852Lawrence, T. S., 2964Lee, I. W., 3062Lee, S. W., 3062Leo, 0., 2973Lerman, M. I., 2852, 3021Limes, P., 2848Uebert, M., 3062Ling, N., 2934Linnainmaa,K., 2919Liu, Y-X., 2943Ljung,B-M., 3021Lehman, P. H. M., 3001Longo,D. L, 2969Lovell, M. A., 2869Luqmani, Y., 2986

Maccia,Y., 3011Mai, M., 2841Manni,A., 2934Masin,D., 2830Matsuda, T., 2895Matsumura,K., 3021Matsunami, N., 2991Maybaum, J., 2964

Mayer, L. D., 2830McLeod, D. 0., 2861Mendonca, H. L, 2845Menton-Brennan, L, 2834Merville,M-P., 2823Metzgar, R. S., 2856Minamoto, T., 2841Mishima, Y., 3011Mitelman, F., 2919Miyake, S., 3007Miyaki, M., 3011Mok, C. H., 2834Mondellini, P., 2979Mori,T.,3011Morimura, T., 2928Morris, S. W., 2873Moser,M., 2973Moul, J. W., 2861Mueller,B. M., 3066Muraoka, M., 3011Myers, C. E., 2923

Nagai, K., 3007Nagashima, Y., 2852Naito, Y., 3034Nakae, D., 2895Nekarda,H., 2900Newman, N. B., 2908Nitiss,J. L., 2943Nordenson,I., 2919

Oda, Y., 2928Ohki, M., 2865Ohtawara,Y., 3034Oldfield,E. H., 2923O'I@car, S., 290801cr, A., 2908Op het Veld, C. W., 3001O'Reilly, S., 2986Orlow, I., 2848Osen, M., 2845

Oshiro,E. M., 2923Otani,S.,2895Oto, M., 3007Otoshi,T., 2895

Pecher, 0., 2856Perry, R. R., 2952Pierotti,M. A., 2979Pileri,S., 2873Pilotti, S., 2979Prough,R. A., 2878Pugh, T. D., 3054

Ram, Z., 2923Redston, M. S., 3025Reuter,V. E., 2848Reuterwall,C., 2919Rice, N. R., 2969Roder, J. D., 2900Rooker,J. A., 2845

Salomaa,S., 2919Samid, D., 2923Samowitz, W., 2991Santoro,M., 2979Sasaki, M. S., 3042Sawaguchi,K., 2841Schmitt,M., 2900Schoenfeld, A., 2986Sehested,M., 2959Sesterhenn,I. A., 2861Seymour, A. B., 3025Shack, S., 2923Shen, 0., 3034Shibagaki,I., 2996Shimada,Y., 2996Shimasaki,S., 2934

3075

Shimizu, K., 2865Shimizu, 1., 3042Shousha,S., 2986Shuin, T., 2827, 2852Sica, A., 2969Siewert, J. R., 2900

Sinnett, H. D., 2986Skerfving,S., 2919Smith,D.,2986Smith,H. S.,3021Sørensen,B. S., 2959Sorsa, M., 2919Srivastava,S., 2861Stahl,A., 3066Stein, H., 2873Stetson, P. L., 2964Sugimura, H., 3034Sugimura, T., 2841Suzuki, M., 3034

Takada,N., 2895Takahashi, H., 3011Takeuchi, J., 2928Tanaka, K., 3011Tanaka, M., 3034Tao-Cheng,J-H., 2923Tatum, A. H., 2908Thibault, A., 2923Thielemans, K., 2973Thliveris, A., 2991Toguchida,J., 3042Torigoe, S., 2827, 2852Tsuruga, H., 2827

Uemura, H., 2827Ulm, K., 2900

van Zeeland,A. A., 3001Veit, L. J., 2908Viola, J. J., 2923Vogelsang,H., 2900Volk, M. J., 3054Vrieling, H., 3001

Wadayama, B., 3042Wagata, 1., 2996Walbridge, S., 2923Waidman,F. M., 3021Waxman, D. J., 2878Webb, S. J., 2878Wei, L., 2934Weindruch, R., 3054Wenninger. A., 2900White, R., 2991Wilson,P. 0. 0., 2914Wiltrout,R. H., 2969Wu,H-Q.,2878

Xiang, Y-Y., 3034

Yamamuro,T., 3042Yamashita, N., 2841Yano, Y., 2895Yao, M., 2852Ye, J., 2969Ych, Y., 2943Yeo, C. J., 3025Yin, D., 2928Yoshino, K., 3007Young, H. A., 2969Yuasa, Y., 3007

Zaenglein, A., 2934Thar, B., 2852Zdzienicka,M. Z., 3001

BENEFITS OF MEMBERSHIPA complete application consists of the following material:1. 6 copies of the form on the opposite side of this page, with all

requested information provided.2. 5 copies of the candidate's most current curriculum vitae and

bibliography.3. 5 copies of a letter of recommendationfrom a nominator who is

an active, corresponding, emeritus, or honorary member of theAACR (at least one copy must be a signed, original letter). Thisletter should describe the candidate's achievements in laboratoryresearch, clinical investigations, or epidemiological research, andit should affirm that this research adheres to accepted ethicalscientific standards. —OR—The nominator may supply theresponses requested at the bottom ofthe application form in thesection entitled “STATEMENTOF SUPPORT―(at least one copyof the form must be the signed original).

4. 5 copies of a letter of recommendation as described in Item 3above from a seconder who is an active, corresponding, emeritus,or honorary member of the AACR (at least one copy must be asigned, original letter). —OR—The seconder may supply theresponses requested at the bottom of the application form in thesection entitled “STATEMENTOF SUPPORT―(at least one copyof the form must be the signed original).

5. 5 reprints of each of two publications on which the candidateappears as author.All material should be collated into five complete sets with the

original application form as a covering document and sent to theaddress given below. Questions regarding procedures for membership application may also be directed to the following address:

American Association for Cancer ResearchPublic Ledger Building

620 Chestnut StreetSuite 816

Philadelphia, PA 19106-3483Phone: 215/440-9300FAX: 215-440-9313

RESPONSIBILITIES OF MEMBERSHIP

Candidates should be aware of the following responsibilities ofmembership in the AACR. Active members must pay annual dues,a major portion of which is designated for subscriptions to AACRpublications. In 1994 dues for active members are $150, $95 ofwhich is designated for journal subscriptions. Newly electedmembers of the AACR who have already purchased subscriptionsto Cancer Research, Cell Growth & Differentiation, or CancerEpidemiology, Biomarkers & Prevention at the higher, nonmemberrate will receive reimbursement of the unused portion of thosesubscriptions once their first year's membership dues are paid infull.

Corresponding members are required to pay dues ($65 in 1994)and may, if they wish, subscribe to Cancer Research, Cell Growth& Differentiation, or Cancer Epidemiology, Biomarkers & Prevention at reduced member rates.

Applicants elected in March will be responsible for payment ofthat year's dues; applicants elected in July and November will paydues for the following year. Applicants elected in March and Julywill be eligible to sponsor an abstract for the next annual meeting.Every effort will be made to afford the same opportunity toapplicants elected in November.

Margaret FotiExecutive Director

The American Association for Cancer Research (AACR), ascientific society consisting of laboratory and clinical cancerresearchers, was founded in 1907 to facilitate communication anddissemination of knowledge among scientists and others dedicatedto the cancer problem; to foster research in cancer and relatedbiomedical sciences; to encourage the presentation and discussionof new and important observations in the field; to foster publiceducation, science education, and training; and to advance theunderstanding of cancer etiology, prevention, diagnosis, andtreatment throughout the world.

Members of the AACR enjoy the following benefits:

1. subscriptions to all of the Association's high-quality journals,Cancer Research, Cell Growth & Differentiation, and CancerEpidemiology, Biomarkers & Prevention, at reduced memberrates;

2. theprivilegeofsponsoringapaperforpresentationattheAACRannual meeting;

3. an advance copy of the scientific Program and the Proceedingsofthe American Association for Cancer Research for each annualmeeting;

4. reduced registration rates at all scientific meetings;5. priority notification of events in the AACR's outstanding series

of special conferences on timely subjects in the field;6. the receipt of AACR newsletters, meeting announcements, and

an up-to-date membership directory;7. reduced rates for the AACR Employment Register; and8. the professional benefits of AACR's public education activities.

QUALIFICATIONS FOR MEMBERSHIPActive membership in the AACR is open to investigators who

live in the Americas. Individuals who have conducted two years ofresearch resulting in peer-reviewed publications relevant to cancer,or who have made substantial contributions to cancer research inan administrative or educational capacity, are eligible. If acandidate is working in a research area not directly related tocancer but has conducted research of merit in a related area ofbiomedical science, he or she may also qualify for membership.

Corresponding membership is open to persons who are notresidents of the Americas. The qualifications for correspondingmembership are the same as those for active membership. Visitingscientists from outside the Americas who intend to return to theircountries of origin by the anticipated time ofelection should applyfor corresponding membership. All other visiting scientists shouldapply for active membership and transfer to corresponding statusat a later date upon leaving the Americas. Graduate and medicalstudents, postdoctoral fellows, and physicians in training who donot yet meet the above qualifications should apply for associatemembership.

PROCEDURES FOR APPUCATIONThere are three deadlines for receipt of a membership applica

tion: January 1, May 1, and September 1 of each year. TheMembership Committee will review all complete applications foractive membership that have been received by these deadlines and

will submit recommendations on each candidate to the Board ofDirectors which formally elects all members. The same procedureis followed by the Special Memberships Committee which receivesapplications for corresponding membership. Candidates will benotified according to the following schedule:

Receipt of Applicationin AACR Office Notification of Candidate

January 1May 1September 1

MarchJulyNovember

AMERICAN ASSOCIATION FOR CANCER RESEARCHGUIDELINES FOR APPLICATION FOR ACTIVE AND

CORRESPONDING MEMBERSHIP

(City) (State/Province)

TELEPHONE NUMBER:___________________________(Country)

(Postal Code)

FAXNUMBER:_________________________E-MAILNUMBER

PRIMARY FIELD OF RESEARCH (Please check only one):Biochemistry and Biophysics Biostatistics

Cellular Biology and Genetics Clinical InvestigationsEpidemiology ...jmmunology

Preclinical Pharmacology and VirologyExperimental Therapeutics(CARRIER):_____________________________________Carcinogenesis

EndocrinologyMolecular Biology and Genetics

Other:___________________________________(Pleasespecify)ACADEMIC

DEGREES (Including where and whengranted)EXPERIENCE

SINCE HIGHEST DEGREE WAS GRANTED (Please list most recent first)

AMERICAN ASSOCIATION FOR CANCER RESEARCH, INC.@Public Ledger Building . 620 Chestnut St. . Suite 816 . Philadelphia, PA 19106-3483 (f

APPLICATION FOR ACTIVE OR CORRESPONDING MEMBERSHIP

NAME OF CANDIDATE:__________________________________________ DATE OF BIRTH:_________LAST FIRST MI.

PRESENT POSITION/TITLE:_

INSTITUTIONAL AFFILIATION:

INSTITUTIONAL ADDRESS:

PUBLICATIONS (Reprints of two peer-reviewed articles on which the candidate appears as an author must accompany thisapplication. For these two articles list the authors, title, journal, volume, inclusive pages, and year. Do not submit abstracts.)

CANDIDATE CANDIDATE

NOMINATED BY*:___________________________ SECONDED BY*:__________________________(Please print) (Please print)

CANDIDATE IS APPLYING FOR (Check one): 0 ACTIVE 0 CORRESPONDING MEMBERSHIP

STATEMENT OF SUPPORT (in place of letters of recommendation)Instead of submitting letters of recommendation, either the nominator or the seconder or both may complete the following section:

How long has the candidate worked in the field of cancer How long has the candidate worked in the field of cancerresearch? @@years research? @@yearsWill the candidate make a long-term contribution to cancer Will the candidate make a long-term contribution to cancerresearch? Yes ..No research? ...........Yes _NoDoes the candidate's research adhere to accepted ethical Does the candidate's research adhere to accepted ethicalstandards? .Yes ...No standards? ..Yes ...NoI therefore recommend this candidate for membership in the I therefore recommend this candidate for membership in theAmerican Association for Cancer Research. American Association for Cancer Research.

Signature of nominator* Date Signature of seconder* Date

See Guidelines for Application on the reverse side of this form for further instructions.

*Both nomnator and seconder must be active, corresponding, emeritus, or honorary members of the AACR.

(This form may be reproduced.)

GUIDELINES FOR APPLICATION FOR ASSOCIATE MEMBERSHIP

QUALIFICATIONS FOR MEMBERSHIP

Associate membership is open to graduate students, medicalstudents, postdoctoral fellows, and physicians in training who arefollowing a course of study or who are working in a researchprogram relevant to cancer. Scientists in training who alreadyhave a substantial record of publications may wish to apply foractive or corresponding membership which confers full benefits ofmembership.

BENEFITS OF MEMBERSHIP

The American Association for Cancer Research (AACR), ascientific society consisting of laboratory and clinical cancerresearchers, was founded in 1907 to facilitate communication anddissemination of knowledge among scientists and others dedicatedto the cancer problem; to foster research in cancer and relatedbiomedical sciences; to encourage presentation and discussion ofnew and important observations in the field; to foster publiceducation, science education, and training; and to advance theunderstanding of cancer etiology, prevention, diagnosis, andtreatment throughout the world. Associate members of the AACRenjoy the following benefits:

1. the privilege ofsponsoring a paper for presentation at the AACRannual meeting provided that (a) the associate member is thepresenter of the paper and (b) an active, corresponding, emeritus, or honorary member in good standing of the AACR alsosigns the abstract of the paper in support of the work (In thisinstance, the member who cosigns the abstract does not lose hisor her own sponsorship privilege.);

2. an advance copy of the scientific Program and (if one has beenpurchased by the associate member) the Proceedings of the

American Association for Cancer Research which containsabstracts of all papers being presented at each annual meeting;

3. the privilege of registering for the annual meeting at the lowstudent rate (This rate is otherwise available only to predoctoralstudents.);

4. preferred access to the AACR Employment Register;5. optional subscriptions to the Association's high-quality journals

Cancer Research, Cell Growth & Differentiation, and CancerEpidemiology, Biomarkers & Prevention at reduced memberrates;

6. priority notification of events in the AACR's series of specialconferences on timely subjects in the field;

7. reduced registration rates at special conferences;8. the receipt of AACR newsletters, meeting announcements, and

an up-to-date membership directory; and9. the facilitation of informal scientific exchange with leading

researchers in the cancer field.

PROCEDURES FOR APPLICATION

Persons wishing to apply for associate membership must use theofficial application form on the reverse side of these instructions.Each candidate for associate membership must be nominated by anactive, corresponding, emeritus, or honorary member in goodstanding of the AACR. Three completed copies of the form shouldbe submitted; at least one of these copies must carry the original

signatures of both the candidate and the nominator. The applica

tion form may be submitted to the Association Office at any time.

After review of applications for associate membership, theExecutive Director will notify candidates of their election ordeferral within one month of the receipt of the application form.A check for one year's dues payment must accompany the application. Dues are currently $30 for associate members residing in theAmericas and $40 for residents of other countries. This fee will berefunded to any candidate deemed to be ineligible for associatemembership. Checks should be in U.S. currency, made payable to

AACR, Inc., and drawn on a U.S. bank. Send the three copies ofthe application form and the $30 or $40 dues payment to:

American Association for Cancer ResearchPublic Ledger Building

620 Chestnut StreetSuite816

Philadelphia, PA 19106-3483215/440-9300

RESPONSIBILITIES OF MEMBERSHIP

Associate members must pay annual dues in an amount to bedetermined by the AACR Board of Directors. Dues for 1993 and1994 have been set at $30 per year for residents of the Americasand $40 for residents of other countries. If an application issubmitted by August 31, the accompanying dues payment will becredited to the current year. Candidates submitting applicationsbetween September 1 and December 31 may indicate whether theywish their dues payments credited to the current or forthcomingyear. Candidates should be aware, however, that associatemembers may sponsor an abstract for the annual meeting only iftheir dues for the current year are paid. For example, an associatemember submitting an abstract in October 1993 for the forthcoming annual meeting must have paid dues for 1993. Any newlyelected associate members of the AACR who have already purchased subscriptions to Cancer Research, Cell Growth & Differentiation, and Cancer Epidemiology, Biomarkers & Prevention at thehigher, nonmember rate will receive a refund for the unusedportion of that subscription upon receipt of their payment for amember's subscription.

Each Fall the AACR will send to current associate members aninvoice for dues for the forthcoming year. Payment of this invoice

must be accompanied by a statement signed by the associatemember's current registrar, dean, or department head, verifyingthe member's current academic status. The Association's By-Lawsstate that dues are payable for each year in advance by January 1of the year to which they should be applied. An individual may bean associate member for a maximum of five years. Each year inwhich an individual pays dues will count as one full year ofassociate membership. Thus, an associate member who pays duesfor 1993 may retain associate membership until December 31,1997. The Board ofDirectors may terminate the membership of anassociate member whose dues are in arrears for two years.

Margaret FotiExecutive Director

AMERICAN ASSOCIATION FOR CANCER RESEARCH

AMERICAN ASSOCIATION FOR CANCER RESEARCH, INC.Public Ledger Building . 620 Chestnut St. . Suite 816 . Philadelphia, PA 19106-3483

NAME OF CANDIDATE:_________________________________________ DATE OF BIRTH:_________LAST FIRST MI.

INSTITUTIONAL AFFILIATION:_____________________________________________________________INSTITUTIONAL ADDRESS:

(City) (StatefProvince) (Country) (Postal Code)

TELEPHONE NUMBER:___________________________ FAX NUMBER:______________________

PRESENT ACADEMIC STATUS/TITLE (Please check only one): E-MAIL NUMBER (CARRIER):___________________....Graduate Student ............Medical Student

Physician in Training ..........Postdoctoral Fellow

PRIMARY FIELD OF RESEARCH (Please check only one):..........Biochemistry and Biophysics Biostatistics ...........Carcinogenesis................CellularBiology and Genetics Clinical Investigations Endocrinology.......Epidemiology ...jmmunology Molecular Biology and Genetics

Preclinical Pharmacology and ...............Virology _________________________________Experimental Therapeutics (Please specify)

ACADEMIC DEGREES (Please indicate degree(s) acquired to date along with the name of the academic institution and date ofreceipt. Provide information on degree currently being sought and the anticipated date of completion of this degree program.)

RELEVANT RESEARCH EXPERIENCE NOT RELATED TO COURSE WORK (Please list most recent first.)

PUBLICATIONS (List the authors, title, journal, volume, inclusive pages, and year of any article in a peer-reviewed journal onwhich the candidate appears as an author. Do not list abstracts. Continue on a separate sheet, if necessary.)

CANDIDATE NOMINATED BY:_________________________________________________________(Please type or print name of AACR active member in good standing.)

SIGNATURESI hereby apply for associate membership in the American Association for Cancer Research. I have read the instructions on thereverse side of this form, and I understand the privileges and responsibilities of this class of membership. I certify that thestatements on this application are true.

Signature of Candidate:___________________________________________________________ Date:_________________

I recommend this candidate for associate membership in the American Association for Cancer Research. To the best of myknowledge, the candidate is qualified for this class of membership, and the statements on this application are true.

Signature of Nominator*:______________________________________________________________ Date:__________________

Submit three copies of this form. At least one copy must contain the original signatures of the candidate and the nominator.Enclose a check in U.S. funds, made payable to AACR, Inc., and drawn on a U.S. bank for one year's dues. Dues are currently $30for associate members residing in the Americas and $40 for residents of other countries.

Check one of the following boxes only if this form is being submitted between September 1 and December 31:The enclosed dues payment should be applied to the 0 current 0 forthcoming calendar year.

(NOTE: Ifdues are applied to the forthcoming year, membership will take effect on January 1, but the candidate will not be eligibleto sponsor an abstract for presentation at the annual meeting in May of that year.) See Guidelines for Application on the reverseside of this form for further instructions.

*Nomjnator must be active, corresponding, emeritus, or honorary member of the AACR.

(This form may be reproduced.

PLEASE FILL OUT ALL INFORMATION ON REVERSE SIDE AND SUBMIT THIS FORM WITH YOUR DISK.DISKS WILL NOT BE PROCESSEDWITHOUT THIS INFORMATION.

toAmericanAssociation for Cancer Research Publications

Theword processingpackagesthat we preferareas follows:

XyWrite Ill Plus (for the IBM)WordPerfect4.2, 50, 5.1 (for the IBM)WordPerfect(fortheMac)Wordstar(for the IBM)

Alsoacceptable:

AppleII DOS3.3Applewith AppleworksSoftwareAppleIll PlusDOS3.3AppleMacIntosh400KDisc/

MacWrite2.2 (text)AppleMacintoshPlus800KDisc/

MacWrite4.5 (text)CPT8000DECWPS-8DECDecmateIIDECDecmateIIIDisplayWrite3

Microsoft Word (for the IBM)MicrosoftWordMacintosh

(Versions1—4)400/800KWangOIS(WPS)

DisplayWrite4IBMDisplaywriterWordProcessor6580LanierBusinessOneStepLanierNo ProblemLanierSuperNo ProblemMASS-ii PCMultimatePCWritePFSProfessionalWriteVolkswnter4.0

New releases of word processing software are not always immediately available for conversion. In addition,because of the file structures and intemal coding, we cannot accept disks created on desktop publishingsystemsor thosecreatedon proprietarytypesettingsystems.Wealsocannotguaranteethat all specialcharacterscanbetranslated.Tabularandmathematicalmaterial,suchasequations,willnotbecapturedfromthe disk but will be rekeyed.

To expeditework andfor your own security,we do requirethat you submita hardcopy printoutof the diskfile.Thetablesandequationswillbekeyedfromthishardcopy.Wealsoneedto knowthenameof thefiletobeconverted,thetypeofhardware(e.g., IBMPC)onwhichthefileswerecreated,theoperatingsystem(e.g.,DOS3.3),andtheversionof thesoftware(e.g., WordPerfect5.1)usedto createthefile.

Guidelinesfor SubmittingDisks

P

DISK SUBMISSIONFORM

AACRjournalsare now usingpersonalcomputersto copyeditmanuscriptsacceptedfor publication.Whensubmittinga revisedmanuscript,authorsareencouragedto submitanelectronicdiskof thepaperalongwiththe required four hard copy printouts. Disks will ultimately be returned to the authors.

I Seereverseforthewordprocessingpackagesthatcanbeaccepted@@Filepreparation

Pleasebesurethatthefileyousendis themostrecentversionof themanuscriptandthat it matchesthemost recently submitted printed copy. The file should contain all the parts of the manuscript in one file.Mathematicalandtabularmaterial,however,willbeprocessedinthetraditionalmannerandmaybeexcludedfrom the disk file.

Note: AACR does not assume responsibility for errors in conversion of customized software, newly releasedsoftware, or special characters.

Please label the outside of the disk with the journal name, the first author's name, a partial title of themanuscript,andthe nameof the computerfile usedto accessthe manuscripton disk.To processyourdiskefficiently,weneedthefollowinginformation.Pleasebesureto provideALLtheinformation.

Nameusedto accesspaperondisk:____________________Nameof computerused(e.g., IBM/PS2):Operatingsystem and version (e.g., DOS3.3):Wordprocessingprogramandversion(e.g.,WordPerfect5.0):

[See reverse for acceptable programs.]

Manuscript number:__________________________________First author _____________________________________Correspondingauthor (if different from first author):Telephone/FAXnumbers:____________________________

This form (both @des)may be reproduced.

IBMS

AACR

Yung-ChlChengI NewHavenChairperson

BruceA.ChabnerI BethesdaCo-Chairperson

JosephR.BertinoI NewYorkCo-Chairperson

EdwardBresnlckI HanoverRobertL CapizzlI PhiladelphiaPaulP.CarboneI MadisonMargaretFotiI PhiladelphiaI.BernardWeinsteinI NewYorkWendellWierengaI AnnArbor

KuangV.ChenI TaipeiK.C.ChowI TaipeiMing-TaHsu/TaipeiOliverYoa.PuHuI TaipeiJaulangHwangI TaipeiGI-MingLaiI Tao-YuanTe-ChangLeeI TaipeiReury-PerngPemgI TaipeiWen-KuangYangI TaipeiWinstonC.Y.VuI Taipei

DrugDiscovery*J. K.Lin I Taipei@BruceA. Chabner I Bethesda

SteveR.Roffler/TaipeiJaulangHwangI TaipeiWendellWlerengaI AnnArborRobertC.JacksonI SanDiegoAllen I. Ollff/ West PointGraceW.P.ChaoYehI Frede@ck

TumorBiology*MjegTaHsuI Taipei

@ Bresnick I HanoverPel-JerChenI TaipeiCheng-PoHuI TaipeiTheaD.‘listyI ChapelHillWen•HwaLeeI SanAntonioChawnshangChangI MadisonLotharSchwelgererI Heidelberg

HepatocellularCarclnogenesis:TreatmentandPrevention

*1BernardWeinsteinI NewYork*Juel LowSung I TaipeiGI-MIngLalI Tao-YuanDIng-ShlnnChen I TaipeiZhao-YouTan9 I ShanghaiYung-ChlChengI NewHavenBrianI CarrI Pittsburgh

GeneTherapyandVaccines@ R.BertinoI NewYork

*DIngShlnnChenI TaipeiUh-HwaHwang/TaipeiWen-KuangYangI TaipeiDrewU.PardollI BaltimoreAlanGewlrtzI PhiladelphiaLeafHuangI PittsburghJ. MartinBrownI Stanford

NovelTherapy@And@wT.HuangI Taipei@l'@uIP.CarboneI Madison

Yao-ChangChen I TaipeiKuangY.ChenI TaipeiRoIfF.BarthI ColumbusMakotoOgawaI NagoyaMarkKamlnskyI AnnArborAliceL YuI SanDiego

ExperimentalTherapeutics@Ro@L CaplzzlI Philadelphia

*W@I WierengaI AnnArborFeliciaY.-H.WuI TaipeiShuen-KuelLIaoI Tao-YuanSusanB.HorwltzI BronxNapoleoneFerrara/S.SanFranciscoRulHanI BeijingEdwardChuI Bethesda

DrugResistance@SusanB.HorwltzI Bronx@MI@hlegShet@I Taipei

ChuckC.-K.ChaoI Tao-YuanTakashi Tsuruo I TokyoJosephR.BertlnoI NewYorkJohnA. HickmanI ManchesterSusanP.C.ColeI KingstonYves Pommler/ Bethesda

SummaryBruceA.ChabnerI Bethesda

Applicantsare encouragedto submitabstractsfor posterpresentation.

*indicetes Session Chairperson

InformationandApplicationForms

AmericanAssociationfor CancerResearch

Public Ledger Building, Suite 816150 South independence Mall WestPhiladelphia, PA 19106-3483215-440-9300 21 5-440-931 3 (FAX)

Instituteof BiomedicalSciencesdo Ms. iris LiIBMS, Academia SinicaTaipei 115, Taiwan, R.O.C.886-2-789-9007886-2-782-5573 (FAX)

MODERNDEVELOPMENTSIN CANCERTHERAPEUTICS

Joint Conference of theAmerican Associationfor Cancer Research

and theInstitute of BiomedicalSciences (Taiwan)

November7-11,1994AcademiaSinica,Taipei,Taiwan

ORGANIZING COMMITTEE

TAIWAN

Cheng-WenWuITaipeiChairperson

JacquelineJ.K.Whang-Peng/TaipeiCo-Chairperson

FellciaY.-H.Wu I TaipeiCo-Chairperson

ChungmingChangI TaipeiKennethS.S.ChangI Tao-YuanDing.ShinnChenI Taipei

SCIENTIFICPROGRAM

AUDIO CASSETFE DISCOUNTS

l-5cassettes $11.50

6-Il cassettes 5% DISCOUNT

12-24cassettes 10% DISCOUNT25-48cassettes 15%DISCOUNT49+ 20%DISCOUNT

Programs consist of 1,2, or 3 cassettes. Prices are listed after each program title.

0 CAN-401MeettheExpertSunriseSession:Anti-GrowthFactorTherapytoPreventandTreatLungCancer:ANewHorizonora Fantasy?PaulA.Bunn,Jr.(I cassette,$1130)

DCAN-402MeettheExpertSunriseSession:CancerCellStructureandChaos,DonaldS.Coffey(I cassette,$1130)

0 CAN-403MeettheExpertSunriseSession:MolecularBiologyofHematopoieticMalignancies,CarloM.Croce(1cassette,$1130)

0 CAN-404MeettheExpertSunriseSession:NewFrontiersinChemoprevention:BasicScience to the Clinic, Waun Ki Hong (1 cassette, $1130)

0 CAN-405PlenarySession:BiologicalandClinicalRolesofGeneticMarkers(2cassettes,$23.00)

0 CAN-406MinisymposiumEndocnnologyI:HormonalCarcinogenesisandProgression(2 cassettes,$23.00)

0 CAN-407MinisymposiumImmunology/BiologicalTherapy1:Antibody-basedTherapyofCancer(3cassettes,$3430)

0 CAN-408MinisymposiumClinicalInvestigationsI:ClinicalPharmacology/PhaseIStudies(3 cassettes,$34.50)

a CAN-409MinisymposiumCarcinogenesisI:AngiogenesisandNeoplasia(3cassettes,$3430)

0 CAN-410MinisymposiumExperimentalTherapeutics1:TopoisomeraseI(3cassettes,$34.50)

0 CAN-41lThirty-FourthG.H.A.ClowesMemorialAwardLecture:GeneticAnalysisofHumanBreastCancer,Mary-ClaireKing(I cassette,$1130)

0 CAN-412MinisymposiumPrevention2:TranslationofChemopreventiontoHumans(3 cassettes, $34.50)

a CAN-4l3MinisymposiumBiology4:SignalTransductionandOncogenesinBreastCancer(3 cassettes,$34.50)

0 CAN-4l4MinisymposiumClinicalInvestigations3:DrugResistance(3cassettes,$34.50)0 CAN-415MinisymposiumExperimentalTherapeutics7:P-GlycoproteinII(3cassettes,

$34.50)

0 CAN-431Symposium9:TranscriptionalControlofCellProliferationandDifferentiation(2cassettes,$23.00)

0 CAN-432MinisymposiumEpidemiologyI:CancerEpidemiologyI:(2cassettes,$23.00)0 CAN-433MinisymposiumCarcinogenesis9:GenomicInstability(3cassettes,$34.50)0 CAN-434MinisymposiumClinicalInvestigations6:BreastCancerI(3cassettes,$34.50)

0 CAN-435MinisymposiumMolecularBiologyfBiochemistry6:AdvancedCancerCytogenetics(3cassettes,$34.50)

0 CAN-436MinisymposiumExperimentalTherapeutics13:TopoisomeraseII:(3cassettes,$34.50)

0 CAN-437ControversySessionI: FatandBreastCancer:CananInterventionTrialResolvetheIssue?(I cassette,$1I30)

0 CAN-438ThirdAmericanCancerSocietyAwardLectureonCancerEpidemiologyandPrevention:ThePreventionofHormone-inducedCancers,BrianE.Henderson(Icassette,$1130)

0 CAN-439MinisymposiumBiology11:CellAdhesionandExtracellularMatrixMolecules(3 cassettes,$34.50)

0 CAN-440MinisymposiumCarcinogenesis12:TumorSuppressorGenesII:(3cassettes,$34.50)

0 CAN-441MinisymposiumClinicalInvestigations9:SolidlumorsIII:(3cassettes,$34.50)0 CAN-442MinisymposiumMolecularBiology/Biochemistry9:ControlofGeneExpressionI:

(3cassettes,$34.50)

0 CAN-443MinisymposiumExperimentalTherapeutics21:ModulationoftheMultidrugResistancePhenotype(2cassettes,$23.00)

0 CAN-444Symposium10:ProgrammedCellDeath(2cassettes,$23.00)

0 CAN-445SymposiumI1:NewStrategiesforImmunologicalIntervention(3cassettes,$34.50)

0 CAN-446Symposium12:DietandCancer:TheRoleofProtectiveFactors(2cassettes,$23.00)

0CAN-447Symposium13:BasicandClinicalAspectsofProstateCancer(2cassettes,$23.00)

0 CAN-448ControversySession2:IsMultidrugResistanceanImportantFactorinTherapeuticOutcome?(2 cassettes,$23.00)

0 CAN-449AACRAnnualBusinessMeeting(I cassette,$11.50)

0 CAN-450MeettheExpertSunriseSession:IntrinsicandAcquiredResistancetoAntimetabolites, Joseph R. Bertino (I cassette, $1130)

0 CAN-45lMeettheExpertSunriseSession:PathologyandEpidemiologyofHelicobactorpylon Infection—Is There aCancer Link? PelayoCorrea (I cassette, $1ISO)

0 CAN-452MeettheExpertSunriseSession:MolecularAspectsofBreastCancerProgression, Helene S. Smith ( I cassette, $1ISO)

0 CAN-453MinisymposiumClinicalInvestigations12:RoleofOncogenesinSolidTumors(2cassettes,$23.00)

0 CAN-454MinisymposiumBiology15:CellularandGeneticFactorsinMetastasis(3 cassettes,$34.50)

0 CAN-455MinisymposiumCarcinogenesis16:TumorPromotionII (3cassettes,$34.50)

0 CAN-456MinisymposiumMolecularBiology/Biochemistry13:DNALesions:TheirRecognitionandRepair(3cassettes,$34.50)

0 CAN-457MinisymposiumExperimentall'herapeutics27:TyrosineKinasesandProteinKinaseCasAntineoplasticDrugTargets(3cassettes,$34.50)

0 CAN-458Symposium14:BasicScienceApproachestoBreastCancer(2cassettes,$23.00)0 CAN-459 Symposium 15:Genetic Basis forlumorCell Sensitivityto Radiation(2 cassettes,

$23.00)

0 CAN-4l7SymposiumI:RecentAdvancesinEnvironmentalCarcinogenesis(2cassettes,$23.00)

0 CAN-4l8Symposium2:CellularSignaling(2cassettes,$23.00)0 CAN-419Symposium3:AIDS-relatedMalignancies(2cassettes,$23.00)0CAN-420Symposium4:SolidlumorPhysiologyandTherapeuticApproaches(2cassettes,

$23.00)0 CAN-42lSymposium5:ConductingCancerResearchamongMinorityPopulationsinthe

UnitedStates(2cassettes,$23.00)

0 CAN-422PresidentialAddress:UVRadiationandImmunology:SomethingNewunderthe@ Sun,MargaretL.Kripke;PresentationoftheSecondGertrudeElionCancer

ResearchAward(1cassette,$11.50)

0 CAN-423MinorityIssuesCommitteeSymposium:SurvivalandSuccessinCancerResearch:Toward the Year2000 (2 cassettes, $23.00)

0 CAN-424MeettheExpertSunriseSession:ModulationofGeneExpressioninMultidrugresistantTumorCells,JuneL.Biedler(I cassette,$11.50)

0 CAN-425MeettheExpertSunriseSession:CytochromeP45OIAI:AnExerciseinRegulation,EdwardBresnick(I cassette,$11.50)

D CAN-426MeettheExpertSunriseSession:PhysiologicalResistancetotheTreatmentofSolidTumors,RakeshK.Jam(I cassette,$11.50)

0 CAN-427MeettheExpertSunriseSession:ChemopreventionofBreastCancerAlternativestoTamoxifen and Retinoids,Lee W.Wattenberg(1 cassette, $11.50)

0 CAN-428Symposium6:HematologicalMalignancies:Biologyandmerapy(2cassettes,$23.00)

a CAN-429Symposium7:NewApproachestoCancerImmunotherapy(2cassettes,$23.00)0 CAN-430Symposium8:RetinoidsandCancer(2cassettes,$23.00)

0 CAN-460Symposium16:IntermediateEndpointsinCancerPrevention(2cassettes,$23.00)

0 CAN-46lSymposium17:Pharmacogenetics:RoleofDrugMetabolismPolymorphismsinCancerChemotherapy(2cassettes,$23.00)

0 CAN-462ControversySession3:IsBoneMarrowTransplantationIndicatedforAdultAcuteLeukemiainFirstRemission?(I cassette,$1130)

0CAN-463EighteenthRichardandHindaRosenthalFoundationAwardLecture:Angiogenesisas a Target for CancerTherapy, Marc E. Lippman (I cassette, $1130)

0 CAN-464PublicEducationSession:TheFundingCrisisinCancerResearch:WhatCanWeDo?(l cassette, $11.50)

0 CAN-465MinisymposiumBiology20:ApoptosisIII(3cassettes,$34.50)0 CAN-466MinisymposiumImmunologylBiologicalTherapy10:TumorAntigensandTumor

Vaccines(3cassettes,$3430)

I ____@ AUDIO CASSEYFEORDERFORM I ____iL@@ii85thAnnualMeeting•AmeñcaiiAssociationforCancerResearchiL@i@1@. . J Programsconsistofeitherltape/$1I.50,2tapes/$23.OO,or3tapes/$34.5OfrRIc@s!ND!CATEDAFTEREACHrifLE)[J@.

•1__PLEASE COMPLETEANDRETURN ENTiRE FORM

_________ SENDTO:TEACH‘EM,160EASTILLINOISST.,CHICAGO,IL6061IPHONE: (312) 467-0424 S FAX: (312) 467-9271 •TOLL-FREE: I-800-225-3775

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VIDEO CASSETtE(ALLOW 4-6 WEEKS FOR DELIVERY)

___________ EACHVIDEOPROGRAM _________________ CONSISTSOF _____L@ UNLESSOTHERW@ENOTED_______Full set oft'ideos. $386

0 CAN-405V (2cassettes,$7800)PlenarySession:BiologicalandClinicalRolesofGeneticMarkers

0 CAN-411V Thirty-FourthG.HA.ClowesMemorialAwardLecture:GeneticAnalysisofllumanBreastCancer,Mary-ClaireKing

0 CAN-422V PresidentialAddress:UVRadiationandImmunology:SomethingNewundertheSun,MargaretL.Kripke;PresentationoftheSecondGertrudeElionCancerResearchAward

0 CAN-423V (2cassettes,$78OO)MinoritylssuesCommitteeSymposium:SurvivalandSuccessinCancerResearch:TowardtheYear2000

0 CAN-438VThirdAmericanCancerSocietyAwardLectureonCancerEpidemiologyandPrevention:ThePreventionofHormone-inducedCancers, Brian E. Henderson

0 CAN-463VEighteenthRichardandHindaRosenthalFoundationAwardLecture:Angiogenesisasa TargetforCancerTherapy,MarcE.Lippman

0 CAN-464V PublicEducationSession:TheFundingCrisisinCancerResearch:WhatCanWeDo?

0 CAN-474VThirteenthCorneliusP.RhoadsMemorialAwardLecture:GeneticSuppressorElements:NewToolsforMolecularOncology,IgorB.Roninson

0 CAN-486V ThirteenthBruceF.CainMemorialAwardLecture:CamptothecinandTaxol:FromDiscoverytoClinicalUsage,MansukhC.WaniandMonroeE.WaIl

NAME_________________________________________________ TITLE_________________________________________________

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0 CAN-467MinisymposiumRadiobiology/RadiationOncology5:IrradiationandtheCellCycle(2cassettes,$23.00)

0 CAN-468MinisymposiumMolecularBiologylBiochemistry17:p53Function(3cassettes,$34.50)

0 CAN-469MinisymposiumExperimentalTherapeutics33:GeneTherapyII:(3cassettes,$34.50)

0 CAN-470Symposium18:PotentialApplicationsofAdvancesinCellandMolecularBiologytoNewTherapiesforLungCancer(2cassettes,$23.00)

0 CAN-471Symposium19:GenomicImprintingandItsRoleinCancer(2cassettes,$23.00)

0 CAN-472Symposium20:NovelStrategiesinChemicalPreventionofCancer(2cassettes,$23.00)

0 CAN-473Symposium21:MechanismsandCircumventionofDrugResistance(2cassettes,$23.00)

0 CAN-474ThirteenthComeliusP.RhoadsMemorialAwardLecture:GeneticSuppressorElements: NewTools for MolecularOncology,Igor B. Roninson(I cassette,$1ISO)

0 CAN-475MeettheExpertSunriseSession:MolecularBasisandFunctionalRoleofGlycosphingolipidsand GlycoproteinsinTumor Progressionand Prevention,Senitiroh Hakomon ( I cassette, $11.S0)

0 CAN-476MeettheExpertSunriseSession:VerapamilandOtherMilestonesfortheTherapyof MultidrugResistance,TakashiTsuruo( I cassette,$1ISO)

0 CAN-477MeettheExpertSunriseSession:TheBiologyofRadiationOncology,H.RodneyWithers and William H. McBride (I cassette, $1 ISO)

0 CAN-478Symposium22:TumorSuppressorGenesandCellCycleControl(2cassettes,$23.00)

0 CAN-479Symposium23:HormonalCarcinogenesis:EpidemiologicalandMechanisticStudies (2 cassettes, $23.00)

0 CAN-480Symposium24:TopoisomeraseIInhibitors:MoleculestoMedicine(2cassettes,$23.00)

0 CAN-481MultidisciplinarySessionI:CytokineBiologyandTherapy(2cassettes,$23.00)0 CAN-482MultidisciplinarySession2:TargetingrasforCancerChemotherapy(2cassettes,

$23.00)

0 CAN-483MinisymposiumClinicalInvestigations15:Cytogenetics/MolecularGenetics(3cassettes,$34.50)

0 CAN-484MinisymposiumClinicalInvestigations16:GeneTherapy(3cassettes,$34.50)

0 CAN-485MinisymposiumBiology23:ProteasesandTheirInhibitorsinDifferentiationandCancer (3 cassettes, $34.50)

0 CAN-486ThirteenthBruceF.CainMemorialAwardLecture:CamptothecinandTaxol:FromDiscoverytoClinicalUsage,MansukhC.WaniandMonroeE.Wall(I cassette,$11.S0)

0 CAN-487MinisymposiumCarcinogenesis25:TumorProgressionII (3cassettes,$34.50)0 CAN-488MinisymposiumExperimentalTherapeutics45:Antisense(3cassettes,$34.50)0 CAN-489MinisymposiumClinicalInvestigations19:ClinicalMolecularStudies(3cassettes,

$34.50)0 CAN-490MinisymposiumMolecularBiology/Biochemistry22:TyrosineKinasesand

Phosphatases(3cassettes,$34.50)

0 CAN-491MinisymposiumExperimentalTherapeutics46:ThymidylateSynthase(3cassettes,$34.50)

0 CAN-492Symposium25:IntegrationofCytokinesandRadiation:BiologicalBasisandPreliminaryClinicalTrials (2 cassettes,$23.00)

0 CAN-493Symposium26:CellAdhesioninInvasionandMetastasis(2cassettes,$23.00)

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