1. Aguilar: Acromegaly can be differentiated from gigantism by?

A. In acromegaly, GH is secreted after epiphyseal plates have closed while in gigantism it occurs while epiphyseal plates are still open***

B. in acromegaly, GH is suppressed during glucose tolerance test while in gigantism it is not

3. Mangente: What is true about GH deficiency?

A. Diagnosis established by glucose tolerance test

B. Diagnosis established by insulin tolerance test***

4. Tadlas: True of prolactinoma

C. visual cuts and infertility

D. galactorrhea, related to post partum*** 6. Castañeda: Bright spot is commonly seen in MRI and is almost always present in primary polydipsia but is invariably small or absent in pituitary polydipsia

A. Nephrogenic DI***

B. Pituitary DI

C. SIADH

D. Psychogenic DI 8. Gabor: A defect in thirst mechanism is ________ characterized by chronic or recurrent hypertonic dehydration

A. Primary polydypsia

B. Hyponatremia

C. Adipsic hypernatremia***

D. Dypsogenic polydypsia 9. Robino: Medicaments cause incomplete sexual precocity. Members of the household using them should be investigated. The following are implicated, except:

A. Estrogen containing contraceptive pills

B. Ginseng creams***

C. Anabolic steroids

D. Steroid lotion 10. Tantia: Pituitary chromophrope tumor usually presents as:

A. Visual disturbance

B. Signs of hormone excess***

C. Signs of hormone deficiency

D. Polyuria CHORLA BLOCK 16 Exam (Aug. 4, 2014) Group 8 72. Basmayor: committed step in steroid synthesis A. cholesteryl ester hydroxylase B. Dehydrogenase C. Desmolase*** D. Reductase

73. Hidrosollo: Classic Triad of Pheochromocytoma? Ans. C. Palpitations, Headache (pain), Profuse Sweating (perspiration) 74. Olac: What to measure to differentiate primary from secondary hyperaldosteronism? A. Aldosterone B. Sodium C. Renin D. Potassium 76. Bontia: Stimulates 1-a hydroxylase in kidney A. prolactin*** B. cortisol C. TH D. Aldosterone 78. Onglatco: Which statement is true: A. Vit. D promotes mineralization of osteoid*** B. PTH inhibits P absorption in the gut C. calcitonin promotes renal reabsorption of Ca D. both PTH and Vit. D promotes osteoblastic activity 80. Sameros: True of Vitamin D A. Low PO4 levels directly trigger 1-hydroxylase production B. Low vitamin D levels promote bone resorption C. Low PTH levels stimulate 1-hydroxylase D. Low PO4 levels directly activate PTH production 81. Vasquez: Evidence points to the following as the possible pathophysiology of thyroid storm: A. Severly elevated serum hyroid hirmonelevels due to chronic excess production of the hormone B. Stimulation of alpha adrenergic receptors C. Sudden acute increase in thyroid hormone level associated with increase circulating catecholamine *** D. Decreased thyroid hormone binding receptors increasing hormone levels CHORLA BLOCK 16 BLOCK EXAM 4 (August 4, 2014) Group 6

51. Alonsabe, Argee: Which of the following

adiposity hormones are responsible for

weight gain:

a. Ghrelin***

b. Leptin

c. Insulin

d. Growth hormone

52. De Jesus, Brian Vale: Hormone involved in

the promotion of satiety right after a meal:

a. Insulin

b. Ghrelin

c. Cholecystokinin

d. Leptin***

53. Magbanua, Cyril Franz:

54. Rapuso, Reginald: Function of neuropeptide

Y:

a. Stimulate leptin

b. Stimulate sympathetic response

c. Satiety

d. Promote weight loss

55. Atotubo, Jennilyn: Obese patient have

difficulty losing weight due to:

a. Decrease leptin

b. Decrease inhibition of neuropeptide

y due to resistance to leptin

c. Decrease sensitivity to ghrelin and

insulin

d. Decrease sensitivity to

neuropeptide y

56. Co, Maria Dolores: How does secondary

aldosteronism cause hypotension:

a. Decrease mineralocorticoids

b. Increase renin substrate***

c. Increase sensitivity to angiotensin

d. Decrease response to prostacyclin

57. Gonzaga, Kenny Rose:

58. Maputol, Ana Isabel: The most appropriate

maneuver to do in patient in number 57 (3

hours post total thyroidectomy patient

developed enlarging neck mass and

breathing difficulty) is/are:

a. Observe only because symptoms

are only temporary

b. Open operative wound site to

release the pressure***

c. Request for ultrasound

d. Wait for the resident to finish

ongoing surgery then refer

59. Parreno, Domeng: Glucocorticoid

replacement during major illness or surgery:

a. During major illness or surgery,

high doses of glucocorticoid up to

10 times the production are

required to avoid adrenal crisis

(Domeng’s Answer)

60. Salvador Khrisella:

61. Toralballa, Paulyn:

BLOCK 16 (August 4, 2014) GROUP 4 31. dela Llana: Is better for wound healing in dysvascular lymb a. Doppler b. Angiography c. ABG*** 34. Villan, Dakila Vine: Clinical manifestations not seen in prolactin-secreting pituitary adenoma: a. loss of libido b. galactorrhea c. gynecomastia d. menorrhagia 35. Cadete, Ivory June: 36. Daulat, Anne Lorreine: Rate-limiting step of glycogenolysis

Answer: glycogen phosphorylase 37. Fuentes, Elyssa Marie: False about pentose pathway? a. No ATP produced b. NAD used as H+ acceptor c. creates ribose d. starts with G6PD 38. Locsin, Russel: What is the ideal management for an elderly with hyperthyroid small goiter and improves upon taking PTU? a. RAI*** b. Thyroid surgery c. Methimazole d. Lithium 39. Peñas, Paterce: Treatment in DM which stimulates insulin secretion: b. Sulfonylurea*** c. Biguanides d. Thiozinediones 39. In xerophthalmia, a dose of 10, 000 IU should be given in pregnant women 40. Silva, Alyssa Joy: Oral hypoglycaemic agent proven to be safe in children: a. Metformin*** b. Repaglinide c. Pioglitazone d. Insulin