Pure Protein LLC • 655 Research Parkway • Suite 556 • Oklahoma City, OK 73104 www.hlaprotein.com 1 .

sHLA–B*49:01B*4901, B4901, B*49, B49, B49

Serological Name B49

Peptide Load EndogenousModification UnmodifiedConjugation Unconjugated

SKU B4901

Product Description

Allele Name B*49:01

B2m

HLA Class HLA Class I

HLA Gene Locus HLA-B

Alternative Allele Name A Chain B*4901, B4901, B*49, B49, B49

Alternative Allele Name B Chain –

Description

Serological Name B49

Serological Split B21

Bw4/Bw6 Assignment Bw4

Bw4/Bw6 Sequence NLRIALR

Allele Frequency [World Population]

A chain 2.00%

B chain –

Associated products

B4901bioB4901pe

Product datasheet

Recombinant, truncated Class I soluble Human Leukocyte Antigen (sHLA), naturally folded and glycosylated, loaded with endogenous peptides.

Pure Protein LLC • 655 Research Parkway • Suite 556 • Oklahoma City, OK 73104 www.hlaprotein.com 2 .

Product Specification

Product name HLA–B*49:01

HLA Species Human

Host Cell Line Species Human

Clone Designation D10F4

Tail Specification VLDL

Peptide Load Endogenous

Modification Unmodified

Conjugation Unconjugated

Complexity Monomer

Protein Format

Storage Temperature 4˚C (This product should be stored undiluted)

Form Liquid

Concentration 1000.0 µg/µl

Formulation PBS/0.02% Sodium Azide

pH 7.4

Purification Method Affinity Chromatography

Grade Research Use Only [RUO]

Authentication Verification Seqence Based Typing

Protein Sequences

Alpha Chain Sequence

Beta Chain Sequence

Related Products

A0201A0301A2402B0702

GSHSMRYFHT AMSRPGRGEP RFITVGYVDD TLFVRFDSDA TSPRKEPRAP WIEQEGPEYW DRETQISKTN TQTYRENLRI ALRYYNQSEA GSHTWQRMYG CDLGPDGRLL RGYNQLAYDG KDYIALNEDL SSWTAADTAA QITQRKWEAA REAEQLRAYL EGLCVEWLRR YLENGKETLQ RADPPKTHVT HHPISDHEAT LRCWALGFYP AEITLTWQRD GEDQTQDTEL VETRPAGDRT FQKWAAVVVP SGEEQRYTCH VQHEGLPKPL TLRSVVSTDD DLA .

IQRTPKIQVY SRHPAENGKS NFLNCYVSGF HPSDIEVDLL KNGERIEKVE HSDLSFSKDW SFYLLYYTEF TPTEKDEYAC RVNHVTLSQP KIVKWDRDM .

Recombinant, truncated, soluble, non-modified, non-labeled, endogenously loaded

Pure Protein LLC • 655 Research Parkway • Suite 556 • Oklahoma City, OK 73104 www.hlaprotein.com 3 .

Applications

HLA Sandwich ELISAs

HLA Direct ELISAs

HLA-Sera Antibody Assays

HLA Controls in ELISA Assays

HLA Assay Standards

HLA Blocking Assays

HLA Neutralizing Assays

HLA Competition Assays

HLA Bead Assays

HLA Immunization Procedures

Recommended Antibodies

W6/32

Anti-B2m

Allele Frequency

Please note: ALL PRODUCTS ARE FOR RESEARCH USE ONLY. NOT FOR COMMERCIAL USE IN DIAGNOSTIC PROCEDURES.For more information, please visit our Policies section on our website. For licensing inquiries, please contact

licensing@hlaprotein.com

Pure Protein LLC • 655 Research Parkway • Suite 556 • Oklahoma City, OK 73104 www.hlaprotein.com 4 .

Motif

Length Distribution

Please note: ALL PRODUCTS ARE FOR RESEARCH USE ONLY. NOT FOR COMMERCIAL USE IN DIAGNOSTIC PROCEDURES.For more information, please visit our Policies section on our website. For licensing inquiries, please contact

licensing@hlaprotein.com

Pure Protein LLC • 655 Research Parkway • Suite 556 • Oklahoma City, OK 73104 www.hlaprotein.com 5 .

Eplet Assignments B*49:01

Eplet Polymorphic Residues Antibody Reactivity

9H 9H12M 12M24T 24T32L 32L41T 41T Yes

45KE 45K46E Yes66I 66I

66IS 66I67S69TNT 69T70N71T Yes71TN 71T77N74Y 74Y

76EN 76E77N77N 77N80I 80I Yes

81ALR 81A82L83R82LR 82L83R Yes95W 95W97R 97R99Y 99Y

103L 103L113YN 113Y114N116L 116L131S 131S Yes152E 152E

152RE 151R152E156L 156L163L 163L

163LE 163L166E163LW 163L167W Yes193PI 193P194I