Background and History of Laminine

7/31/2019 Background and History of Laminine

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BackgroundandHistoryofLaminine

WHATISLAMININE?

Laminineisanaminoacidpeptidewhichhasalltherequirednourishmenttosustainlife. (Anaminoacidisthe

buildingblockofproteininwhicheachislinkedtogetherthroughpeptidebonds;andapeptideisanamino

acidcompoundthatconsistsof2ormoreaminoacids).

Thereareover100aminoacidsthatoccurnaturally,butonlytwentyofthemareinvolvedinmakingupa

protein,andareclassifiedaseithernonessentialoressential.Nonessentialaminoacidsaresonamed

becausetheycanbesynthesizedinthebody.Theseincludealanine,arginine,asparticacid,asparagine,

cysteine,glutamicacid,glutamine,glycine,proline,serine,andtyrosine.Essentialorindispensableaminoacids

cannotbesynthesizedinthebodyandcanonlybeobtainedthroughfood.Thesebecometheratelimiting

factorsforthesynthesisofcertainproteinsinthebody. Theessentialaminoacidsarehistidine,isoleucine,

leucine,lysine,methionine,phenylalanine,threonine,tryptophan,andvaline.

BeforetheproductionofthesupplementknownasLaminine,noothercompanieshaddevelopedand

marketedacombinationofaminoacids,peptides,andgrowthfactorsrequiredtosustainrobusthealth.

THEHISTORY

OF

LAMININE:

In1929aCanadiandoctor,Dr.JohnRalstonDavison,theorizedthataninjectedextractfromfertilizedheneggs

couldbehelpfulforanumberofhiscancerpatients.Davidsonspentwelloveradecadedevelopingand

researchinghistheory. HepublishedanumberofstudiesonhisdiscoveryintheCanadianJournalof

Medicine,however,whenDr.Davidsonpassedawayin1943,hisresearchonfertilizedheneggsquicklyand

quietlycametoahaltandwaslost.

Itwasntuntilalmost50yearslaterthatthepursuitoffertilizedheneggextractwas

revivedbyNorwaysforemostexpertoneggresearch,

Dr.Bjodne

Eskeland.

Dr.Eskelandalsohypothesizedthatincubated,fertilizedheneggscontainedaspecialcombinationofamino

acids,peptides,andproteinfractionsthatcouldhelpprovideanincrediblearrayofhealthbenefitswhen

consumedbyhumans.

Intheory,thesepartiallyincubated,fertilizedeggsspecifically9dayoldfertilizedeggscontainallthe

nutrientsrequiredtostartanewlife.Thisincludesvitamins,mineralsandproteins,aswellasimportant

defensefactors,growthfactors,hormonesandotherbiologicallyactivecomponents.Whilenotmuchwas

knownaboutthegrowthfactoratthetime,thehighlevelofoligopeptides(smallpeptides)foundinLaminine

allowsforrapidtransportacrossthemembranesofthegastrointestinaltractinordertoprovideeffective

benefitsfromtheseaminoacids.

ManufacturerofLaminine:

Lamininesparentcompany,LifePharmInc.,researchedwhatwasbeingdonewiththiskeyingredient,also

calledYTEorYoungTissueExtract, thathaddemonstratedsomanyhealthassociatedbenefits.

LifePharmcontactedtheteamofscientistsinNorwayworkingwithYTE,andnowhaveexclusiverightsfor

distributionofthisproductunderthebrandname"Laminine"andhaveitmanufacturedexclusivelyforthem.

Apatentedprocessextractsthecriticalnutritionalfluidfromthewhiteofaneggattheprotoembryonicstage

(onlytheeggyolkispresentandnodevelopingchicken),sothemanufacturercalleditProtoEmbryonicStage

Extract(PESE).Theextractnotonlyprovidesamechanismofrapidtransportofverycriticalnutrients,butalso


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containsBasicFibroblastGrowthFactor,whichisprobablyresponsiblefortheaminoacidsandpeptidesbeing

utilizedintherightmanner,bydirectingtheirusebythebody.Thisgrowthfactorisalsoresponsiblefor

nurturingthebodysownstemcellsbothdifferentiated,andundifferentiated(undifferentiatedstemcellscan

rebuildanyofthetissuesofthebody). Commonaminoacidformulationsdonotcontainthisgrowthfactor,

andmaynotbeutilizedbythebraininthemostefficientmanner.

AteamofscientistsleadbyDr.AlexMartin,aleadingdoctorinthestudyofnutritionalsupplements,atthe

LifePharminstituteoftechnologywenttoworktodevelopwhattheytermed"theperfectsupplement".Using

PESEasabaseingredient,theylookedatthesymptomscauseddeficienciesinmostbyourdiets,andthetoxinsinourenvironment,andthenevaluatedmethodstosuperchargethePESEformoderndayuse. Skin

andhair,health,moods(depression),memoryloss,fatigueandcardiovascularhealtharemostcommonly

affectedbytodayslifestyle.ThesesymptomsandhowLaminineaddressesthemarecoveredlaterinthis

booklet.

Havingaperfectlybalanced,natural,transportmechanismwithPESELifePharmknewthattheaddedamino

acidswillnotonlyfindtheirwaytotherightareasofthebody,butwouldbeguidedproperlytoperformtheir

functionefficiently.Themanufacturerthenaddedtheaminoacidsmostcriticalforthehealthofyourskin,

hair,memoryfunction,cardiovascularhealthandrestorationofenergy,fromnaturalplantproteinandmarine

protein.Theseproteiningredientsfromland("phytoproteins"orplantproteinsfromtheyellowpea),sea

(marineproteinsourcesfromsharkcartilage)combinetoformandenhancethepowerfulsymbiotic

relationshipofthebaseingredientinLamininethatiscalledOPT9.

SPORTSNUTRITION

OPT9andcreatinereinforceeachother(thereisnoaddedcreatineintheLaminineproduct).Thenetresultof

usingthiscombinationisimprovedperformance,decreasedfatigue,andareducedriskofenergydepletionin

themuscles.

In1996,adoubleblindtrialontheuseofPESEconductedattheUniversityofColoradoshowedthatthegroup

usingitexperiencedastrengthincreasethatwasnearlydoublethatofthegroupusingcreatinealone.PESE

andcreatinetogetherwerefoundtooutperformcreatineandotherfoodsupplementsintheareasof

endurance,training,motivation,andsubjectivehealthandwellbeing,andithastheenthusiasticendorsement

ofmanytopathletes.Theyreportrecoveringfasteraftertraining.Thisislinkedtoasubstantialreductionin

lacticacidproduction,whichalsocontributestoincreasedstamina.


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ButwhatdoescreatinehavetodowithOPT9?Itappearsthatcreatineandtheeggproteinfractionsthatare

foundinOPT9reinforceeachother,resultinginaprominentincreaseineffectiveness.Thismeansthat

bodybuildersandathletesexperiencegreatlyenhancedbenefitswhenaddingLamininetotheirregimen.No

wondertheproducthastheenthusiasticendorsementofsomanyprofessionalathletesandbodybuilders.

Whetheritisaphysicalormentalchallengeyoufaceorjusttheneedtohandleeverydaydemands,Laminine

mayhelp.

Benefitsmayinclude:

1.Adelayinlacticacidproduction

2.Theabilitytotoleratelongertrainingsessions.

3.ImprovedStamina

4.MaximumMuscularStrength

5.FasterRecoveryaftertrainingsessions

6.Quickerrecoveryfromphysicalexertion

7.Bettermuscletone

8.Increasedmusclestrength

MEMORYENHANCEMENT

ThemostpronouncedeffectofartificialsweetenersandMSGinthebodyistointerferewiththissynergistic

performance.ThemanufacturerthereforedecidedtoaddressthisissuewhentheyformulatedLaminine.

MemoryfunctioniscontrolledbyawellbalancedjointeffectofGlutamateandGlycine.Boththeseamino

acidsactsynergisticallytogethertoplayacriticalroleintheabilityoftwoneuronstoconnect,animportant

cellularmechanismforlearningandmemorytotakeplace. PESEislowintheseaminoacids.Therefore,

LaminineenhancestheselevelsinOPT9bytheadditionofanisolatedvegetableprotein(fromtheyellowpea)

toprovideextraglutamicacidandwithmarineproteinextract(frompurifiedsharkcartilage)toprovideextra

Glycine. PESEisusedtoprovideadditionalFGFintheaidofmemory. FGFisknowntobuildneurites,the

bridgesbetweentheneuronsandwhichactasthereceptorsandtransmittersofsignals. ResearchshowsFGFalsoinhibitsandeliminatesmutantproteingenes,inthiscase,quitepossiblyblockingthegenesresponsible

formemoryloss.

In1962,itwasdiscoveredthatthatneurologicstemcellsresideincertainpartsofthebrain,oftenwhere

damageordysfunctionispresent.ItisalsoscientificallyproventhatFibroblastGrowthFactor(FGF)feedsand

nurturesthesestemcellstofacilitatethehealingofthisdamage,dysfunction,andscarredtissue.Lately,

compellingargumentshavebeenmadetoinjectFGFdirectlytotreatorcureHuntingtonsdisease,

Schizophrenia,OCDandAutism.

Thesynergisticeffectofbuildingtheneurites,nurturingthestemcells,havingthemostrelevantaminoacids

and

factors

to

guide

where

the

amino

acids

go,

makes

Laminine

perform

extremely

well

in

memory

enhancement.

AnotherveryeffectivecombinationinLaminineisthecombinationofthetwoingredientsLeucineand

Isoleucine.ThiscombinationinincreasedbycombiningthePESEandthevegetableproteinextract.Leucine

andIsoleucineprovideingredientsforthemanufacturingofmanyessentialbiochemicalcomponentsinthe

body,someofwhichareutilizedtostimulatetheupperbrainandhelpyoutobemorealertandfocused.

ItsnowondertherehavebeenreportsofmanypositiveeffectsofLamininewithpeoplesufferingfrom

Alzheimerssyndrome,ADD,andageneralincreasedmemoryandmentalfocusinourbusylives.


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MOODENHANCEMENTANDDEPRESSION

Depressioniscausedbymanyinternalaswellasexternalfactors,includingstress. Inthebrain,theserotonin

uptakeandreleasemechanismisaffected. Serotoninisanessentialneurotransmitterwhichhasbeencalled

the"happychemical",asitisassociatedwithfeelingsofcontentment,wellbeingandhappiness. Serotonin

alsosupportscognitivefunctions,includingmemoryandlearning. TheSSRI(SelectiveSerotoninreUptake

Inhibitor)marketisan$18billiondollarperyearmarketprovidingprescriptiondrugswhichhave

demonstratedtheabilitytoincreaseserotoninlevelswithinthenervesynapses,therebycausingmood

improvementandalleviationofdepression. Butthesebenefitsdonotcomenotwithoutsignificantexpenseandsomenotablesideeffects. Conversely,Laminineisanallnaturalproductthatcontainstheaminoacid

Lysine;derivedfromPESEandnaturalvegetableproteins.Thecombinationofthesetwocomponentsdelivers

ahigherlevelofLysineintheOPT9thaneitheringredientwouldbyitself(thisiscalledsynergism).Lysineis

knowntoregulateserotoninlevelsinthebrain.

Some20millionpeopleworldwideexperiencedepressionseriousenoughtowarrantbeingplacedon

prescriptionmedication(usuallyanSSRI).Many,anestimated16to30percent,whotakesuchdrugs

experiencesexualdysfunctionasasideeffect. Somemedicalexpertsbelievethetruenumberofpeople

experiencingthissideeffectmaybeashighas78percentduetothefactthattheconditionoftengoes

unreportedbypatients.ClinicalstudieshaveshownthatLamininemaybebeneficialinenhancinglibidoamong

thosetakingantidepressants.

ManypeopletakingLamininereportapronouncedimprovementintheirmoodandanincreasedabilityto

managestressonadailybasis.Agreateroverallengagewithothersanddesiretoaccomplishthings.

CARDIOVASCULARHEALTHANDLIBIDOENHANCEMENT

ThePESEandVegetableproteinsprovideaverypotentdoseofArginine.Arginineisaprecursorofnitricoxide

andplaysavitalroleinavarietyofbiologicalprocesses.Theinnerliningofbloodvesselsusesnitricoxideto

signalthesurroundingsmoothmuscletorelax,thusresultinginincreasedbloodflow.Effectsinclude

modulationofthehaircycle,andincreasedlibido.Nitricoxideisalsoknownforgrowthhormoneformation,

increasingdefenseoftheinternalorgansagainsteffectsofaging.

REMOVINGTOXINSFROMTHEBODY

PESEcontainsCysteine,whichisaprecursortoglutathione,apowerfulantioxidant,receivingmuchattention

todayforhealthierlookingskin.Antioxidantsfightfreeradicals,(freeradicalsareharmfulcompoundsinthe

bodythatdamagecellmembranesandDNA).Freeradicalsoccurnaturallyinthebody(duringthenormal

energyproducingmetabolicprocesseswithinourcells), butenvironmentaltoxins(includingultravioletlight,

radiation,cigarettesmoking,andairpollution)canincreasethenumberofthesedamagingparticles.Free

radicalsarebelievedtoplayaroleinagingaswellasthedevelopmentofanumberofhealthproblems,

includingheartdiseaseandcancer.

NAC(NAcetylCysteine)isapowerfulantioxidantandcanhelppreventsideeffectscausedbydrugreactions

andtoxicchemicals,andhelpstoalleviateandbreakdownmucusinthebody. NACappearstohavebenefits

intreatingsomerespiratoryconditions,suchasbronchitisandCOPD.Thisisverycrucialforthebodyslife

functions,asNAChelpsthebodyneutralizetoxins,heavymetals,suchasmercuryfromdentalamalgam

fillings,cadmiumandleadfrompaint,andcigarettesmoke.TheSulfhydrylbalancehasalsobeenlinkedto

enhanceresistancetoviralinfections.NACisoneofthemosteffectiveoralchelatingagents.

Takenregularlyoveraperiodoftime,NACwillremovemanytoxicheavymetalsfromthebody.NAChasbeen

showntobeaprotectiveagentinmanydiseasesandconditionsinwhichfreeradicalsplayarole.Thisincludes

cancer,AIDS,cirrhosis,aswellaspollutiondamagefromsmokingorotherchemicals.


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TheaddedpotentdoseofGlycine,fromanaturalmarineproteinsource,furtherenhancestheantiaging

effectofglutathioneinthebody. Glycinefromthemarineproteinalsobuildscollagen,makingtheskinlook

healthierandlesswrinkled.

SKIN,HAIR,&HEALTH

ThemanufacturerhasaddedanadditionalcomponenttoOPT9inLaminine.TheaddedpotentdoseofGlycine,

frommarineprotein,furtherenhancestheantiagingeffectofglutathioneinthebody.Glycinefromthemarineproteinalsobuildscollagen,makingtheskinlookhealthierandlesswrinkled.

Hairiscomposedfromprotein.LCysteineisanaminoacidthatisknowntopromotehairgrowth.

Itimproveshairqualityandtexture,anditisknowntodoublethelengthofhair.LCysteinealsopreventshair

fromfallingout,andithasadetoxifyingeffectinthebody.ThePESEandVegetableproteinsalsoprovidea

verypotentdoseofArginine.Arginineisaprecursorofnitricoxideandtheseeffectthemodulationofthehair

cycle.

THELECITHINCONNECTIONANDCONTROLLINGCHOLESTEROL

Yearsago,pioneeringnutritionistAdelleDavisrecognizedtheerrorintheassumptionthateatingcholesterol

richfoodscausesabuildupofcholesterolinthearteriesandleadstoheartdisease.Shetaughtthatacousin

ofthefatfamily,lecithin,playsavitalroleincontrollingbloodcholesterollevels.Lecithin,foundinthehuman

body(andconcentratedinthebrain),isafatemulsifierthatbreaksdowncholesterol,preventingitsbuildupin

thebody,Lecithinisalsofoundineggs.Whiletheymayprovidecholesterol,theyalsoprovidethelecithin

neededtobreakcholesteroldown.

FATIGUE&ENERGY

LamininecombinesthetwoingredientsLeucineandIsoleucine(knownasbranchedchainaminoacids)from

thePESEwithanaddeddosefromthevegetableproteinextract.LeucineandIsoleucineprovideingredients

forthemanufacturingofotheressentialbiochemicalcomponentsinthebody,someofwhichareutilizedfor

theproductionofenergy,stimulantstotheupperbrainandhelpingyoutobemorealert.

Manypeopletodayaremildlyfatigued,andothersareseriouslyenergydeficient. Fatigueisasymptomthat

accompaniesmostillnesses,bothacuteandchronic:itisoftenanearlywarningsignthatserioushealth

problemsareintheprocessofdeveloping.Persistent,extremefatiguemaybeasignofchronicfatigue

syndrome(CFIDS).TheCenterforDiseaseControl(CDC)estimatesthatchronicfatiguesyndromeaffects

between100,000and250,000peopleintheUnitedStates,butmanyresearchersbelievethatthedisorderis

muchmoreprevalentthanthat.Whatiscertainisthattherearemanytiredpeopleeverywhere

strugglingtogetthrougheachday.

Whetheryoureaprofessionalathleteoraweekendwarrior,youcouldprobablyusemoreenergy,who

wouldnt

want

to

feel

more

energetic,

in

order

to

better

face

the

challenges,

both

physical

and

mental,

in

life.

Thosewhoseworkdemandsmentalconcentrationarebeingsappedofenergyjustlikethosewhohave

physicallydemandingjobs.Whetherthetaskathandisatennismatchorachesstournament,increased

energyandstaminacanleadtoabetteroutcome.

STRESSMANAGEMENT&IMPROVEDSLEEP

UseofLamininepromotesafeelingofrelaxationeffectthatmaybetosomedegreeattributedtothedramatic

decreaseinlevelsofthestresshormonecortisolproducedafterLamininesingestion.

Asindicated,Lamininereducesstresshormonelevelsdramaticallyinthebody.

Whencortisollevelsdecline,wefeelmorerelaxed. StudiesshowthatvirtuallyeveryonewhousesLaminine


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experiencesagreatersenseofrelaxationandwithit,manyextrabenefits,suchasimprovedsleep.

Elevatedlevelsofstresshormonesnotonlymakeusfeelonedge,butalsopredisposeustoanumberof

stressrelateddiseases,whichincludeseriousconditionssuchashypertension,heartdisease,stroke,asthma,

irritablebowelsyndrome,ulcerativecolitis,eczema,andautoimmunedisorders.Bymanagingstresshormone

levels,wemaybehelpingtopreventormanagethesedisorders.

HOWDOESLAMININEWORK&WHAT'SINIT?

WhatdoesOpt9Contain?

OPT9containsanaturalcombinationofnutrients,includingaminoacids,glycopeptides,andoligopeptidesthat

comefromfertilizedeggs,isolatednaturalplantproteins(yellowpea),andnaturalmarineelements(purified

sharkcartilage)thatworktogethertoformasuperfoodornutraceuticalforthesupportofboththemindand

thebody.

TheHealthBenefitsofLaminine

Lamininehasbeenassociatedwithavarietyofpotentialhealthbenefits,including:increasedstrengthand

vitality,improvedstaminaandenergy,increasedlibido(inbothmenandwomen),reducedstress,improved

sleep,quickerrecoveryafterworkoutandimprovedmuscletone,increasedleanmusclemass,increased

alertnessandmentalclarity,reduced"brainfog",improvedmood,improvedcalmnessandhappiness

(Lamininehasbeencalled"thehappypill"),andoverallimprovedsenseofwellbeing.

Thesevariouseffectsmayallberelatedtothesignificantreductionofthestresshormonecortisol(byabout50

percent)aftertheingestionofLaminine,aswellasincreasesinthehappychemical,serotonin. Additionally,

Laminineprovidestheprecursors(buildingblocks)tonutritionallysupporttheproduction,andmaintenanceof

laminininthebody. Lamininistheproteinnetworkfoundationformostcellsandorgansinourbodies.

Lamininsareanimportantandbiologicallyactivepartofthebasallamina,andinfluencehowthecellsofour

bodydifferentiate(stemcells),migrate,holdtogether(adhesion)andsurvive. Lamininhasbeencalledthe

"rebarofthehumanbody"muchlikerebar(strongmetalrods)structurallyholdtogetherandstrengthen

concreteusedtobuildbuildingsandhighways.

WhatexactlyisPESE,andhowmuchisknownaboutitsbenefits?

ProtoEmbryonicStageExtract(PESE)isthenamethemanufacturerhasgiventheingredientinLamininethatis

derivedfromtheliquidwhitesofpartiallyincubated(9daysold)fertilizedorganicheneggs. Thecholesterol

containingyolkisexcluded. PESEcontainsthemostpotentandbalancedcombinationofaminoacids,aswell

asotherfactorssuchasFibroblastGrowthFactor(FGF).Aminoacidsderivedfromsuchfluidscombinedwith

thegrowthfactorsareabletoenhancebrainfunctionbecausetheyarepreciselyengineeredtosupportthe

mostcomplexstageofdevelopmentofalivingcreature,thebeginningoflife.Thisbeginningisthemost

criticalstageinourdevelopment,justlikethetakeoffisthemostcomplexfunctioninflyinganairplane,orthe

foundation(andstructuralrebar)isinconstruction,andisthemostessentialfunctioninthelifeofabuilding.

Thehealthbenefitsofthehenegghavebeenknownforcenturies.Recently,furtherinvestigationofthe

mechanismofthedevelopmentofanembryoinaneggduringincubationhasrevealedthescientific

equivalentofthemiracleoflife.Thepotencyofthenutrientsavailabletotheembryoatthelatterstageof

developmentstagehasalwaysbeenassumedtobehigh,butitwasonlyrecentlythatthechemicalstructureof

theoriginaleggsolidsforthesecriticalstageswasobtained.Duringthisstage,oligopeptideswithsmall

molecularweightswereidentified.Theseshortchainsofaminoacidsareabletocrossthedigestivebarrier

withoutbreakingdownorchangingtheratiosandproportions.Peptidesarefarmorepotentthanother

neurotransmitters,requiringonlysmallamountstoproduceaprofoundeffect. Heatcandestroythesecritical

proteinfactors,andLaminineshouldnotbeheatedover118degrees. Itshouldbeprotectedfromprolonged

exposuretoheat,andshouldneverbemixedintosteaminghotliquids,orbakedintofoods.


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Additionally,theuptakeoftheFibroblastGrowthFactor(FGF)(presentinPESE)bytheembryosharply

increasesandtheFGFpresenthavebeenisolatedthroughapatentedprocesspreciselyattherightstageof

incubation,extractedandfreezedriedtobringthemiracleoflifebenefitstohumans.

ExtractingPESEbeforethepeptidesandFGFareuseduptobuildorgansandbones,allowsustoprovidethis

building,repairing,maintenancemechanismofperfectlybalancedaminoacids,peptidesandgrowthfactorsto

humans.WhilevirtuallyunknownintheUnitedStatesuntilveryrecently,PESEhasbeenmarketedsuccessfully

asanutritionalsupplementinScandinaviaformanyyears.

HowisFibroblastGrowthFactor(FGF)helpfultohumans?

Thepreciseblendofoligopeptidesmaybeseenasbuildingblocks,butwithoutabridge,oramaster

builder/director.TheroleofsuchadirectorisfulfilledbyagrowthfactorknownastheFibroblastGrowth

Factor,orFGF. FGFisprolificinPESE,aswellasinthehumanplacenta.Adetaileddaybydaystudywas

performedin1988. Discoveredfourdecadesagointheseventies,andalsoexistingasapeptide,thisFGFis

criticalinthedevelopmentofembryos,includinghumans.However,itisnotfoundtobecirculatinginthe

humanadultbodies.FGFisresponsibleforbuildingtheliningsinthebloodvessels,creatingtheinfrastructure

forthenutrientstoflowtocriticalareasofthebrainandorgans.ResearchcreditsFGFwiththepotentialto

directlyaffectmanyneurologicdisordersbecauseoftheabilityofFGFtoaffectthegrowthofneurites.

Neuritesaresignalsenders(Axons)andsignalreceivers(Dendrites)thatareattachedtothebrainneurons.

Researchhasalsoclearlydemonstratedthatnewcellculturesshowadramaticincreaseinpeptideandamino

aciduptakeinthepresenceofFGF.Thisresultsupportsthehypothesisthatembryonicgrowthisinfluencedby

averyprecisemechanism,whichcombinesuniquecombinationsofaminoacids,peptidesandFGF.

SinceFGFisnotcirculatinginadults,multipleresearchprojectsontheeffectsofFGFserumstocureneurologic

disordershavebeencarriedout.FundamentaltotheresearchisthefactdiscoveredbyAltmanin1962that

neuralSTEMcellsareformedbythebodyinresponsetoabnormalities,andareresidentincertainzonesofthe

brainundergoingbiologicstress.Thebrainisthereforereadytorepairthedamage,andthesecellshaveshown

todifferentiateintoawiderangeofneurons.Neuronsderivedfromsuchneuralstemcellsarecapableof

migratingtovariousregionsoftheCentralNervousSystem.

Useofvegetableproteins

Vegetableproteinhasanessentialaminoacidprofile,whichisveryclosetothatoftheidealproteinforhuman

nutrition(FAO/WHO1985and2002).ForLaminine,apatentedprocessfurtherisolatestheseproteinsinorder

toeliminateunnecessarycompoundswhichcanneutralizethebenefitsoftheessentialaminoacids.

TheresultisancompoundwhichishighinGlutamicacid,(furtherenhancingthecognitivefunctionofthe

brain),branchedchainaminoacids(tocounterinsomnia),Lysine(tocontrolreleaseofserotonin,controlling

moods),andArginine(promotingNitricOxideandgrowthhormoneformation).Thesespeciallyisolated

proteinscreateasynergisticallypotentcompositiontoenhancebrainactivity.

UseofMarineProteins

ThehighlevelsofGlycineinthespeciallyextractedmarineprotein(purifiedsharkcartilage)usedinLaminine,

combinedwithasignificantamountofhydroxyprolinetostabilizetheglycine,makesitaprimarycandidatefor

aterrificbrainfood. Byitself,Glycineisaneurotransmitter,primarilyutilizedbythebraintocontrolglutamate

levels. In combinationwithinOPT9,itbecomesapowerfulforcetoenhancememoryfunctioninthebrain.

AMINOACIDSANDTHEIRROLES

Aminoacidsarecriticaltolife,andhavemanyfunctionsinmetabolism.Oneparticularlyimportantfunctionis


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asthebuildingblocksofproteins,whicharelinear(straight)chainsofaminoacids.Lamininesuniqueblendof

ingredientscombinestoproduceacompletechainof20aminoacids.Thefollowingisalistofthoseamino

acidsandtheirpotentialbenefits.Aminoacidsareorganiccompoundsthatcombinetoformproteins.When

proteinsaredigested,aminoacidsareleft.Thehumanbodyrequiresanumberofaminoacidstogrowand

breakdownfoodandisaveryimportantpartofnutrition.

AcompletebalanceofaminoarecontainedinLaminineandinclude:

Essential NonessentialorConditionallyEssential

Histidine Alanine

Isoleucine Arginine

Leucine Asparagine

Lysine Asparticacid

Methionine Cysteine

PhenylalanineGlutamicacid

Threonine Glutamine

Tryptophan Glycine

Valine Ornithine

Proline(Hydroxyproline)

Selenocysteine

Serine

Taurine

Tyrosine

Glycineandglutamineareprecursorsofnucleotides.Nucleotidesaremoleculesthat,whenjoinedtogether,

makeupthestructuralunitsofRNAandDNA. Pleasenote: GlutamicacidandGlutamineareNOT

monosodiumglutamate. ThereisnoaddedMSGinLaminine.

Thesebuildingblocksofproteinsperformvariousvitalrolesinthebodyandhelpustoremainhealthyinmany

ways.

Antioxidantshelpingwithcombatingfreeradicalsandenvironmentaltoxinsincludingultravioletlight,

radiation,cigarettesmoking,andairpollution.

Benefitsintreatingsomerespiratoryconditions,suchasbronchitisandCOPD.Angina,Chronicbronchitisand

ChronicObstructivePulmonaryDisease(COPD),Influenza,AcuteRespiratoryDistressSyndrome(ARDS),

HIV/AIDS.

Reducingsymptomsofasthma,cysticfibrosis,andemphysema.

HelpingtoImproveorPreventingcoloncancer.


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HelpingtoImproveorPreventingcataractsandmaculardegeneration.

HelpingincreaseHDLgoodcholesterol.

Helpingincreasefertilitywhentakenalongwithfertilitydrugsinpeoplewithpolycysticovarydisease.

Helpingimproveoutcomeinchildrenwithadvancedcerebraladrenoleukodystrophy,atypeofleukemia.

Helpingtreatcocaineaddiction,schizophrenia,andgamblingaddictions.

Reducinglungcancerriskamongsmokers.

DecreaseCelloxidation.

Enhancesneurotransmittersinthebrain.

Assistintheformationoftoothenamel. Bloodcoagulationregulation.

Immuneresponse.

Increasedmemoryfunction,cognition,andvoluntarymovementandlearningability.

Aidintheeliminationoftoxicammoniaintheformofnitrogenfromthebody.

Improvehairandskin.

Fightinsomnia.

Increaseenergyandendurance.

Regulationofbloodpressureunderstress.

Controlsreleaseofserotoninandmoodimprovement.

Increasedvasodilatationwhichincreasesbloodflow.

Humanswithatherosclerosis,diabetesorhypertensionoftenshowimpairedNitricOxidepathways.

THEROLEOFPEPTIDES

Smallaminoacidchainpeptides(suchasthosecontainedinLaminine),commonlyknownasoligopeptides,are

veryeasilytransportedthroughtheintestinal,membrane.Theyaresometimesusedastransportmechanisms

fordrugs.

Peptidesareshortpolymersformedfromthelinking,inadefinedorder,ofaminoacids.Proteinsaremulti

peptidechains.Proteinsmustbebrokendowntosmallerandsmallerpeptides,andeventuallyanaminoacid,

toperformitsfunctions. Dietaryintakeofpeptidesandaminoacids,whichcanreachtheirdestination,

therefore,canbeextremelybeneficial. Peptidesarethemostabundantcompoundsinthehypothalamusof

thebrain,andperformvitalfunctionsofcommunicatingsensoryimpulsestotheendocrinesystem(hormone

producingglands).

Understandingthemechanismsoftheeffectofpeptides,andthetypesofpeptides,isacomplexfieldandis

beingstudiedextensively.Unfortunately,thesestudiesaredoneinisolationanddisregardthewholepictureof

themanycomplexmechanismswhichexistinourbody.Further,thesestudiesareusuallyfocusedona

particularaminoacid,peptideorotherneurotransmitters.Whiletheresultsidentifythefinalactivitywiththe

aminoacid/peptide,themechanismoftransportofsuchcriticalaminoacid/peptidestothefinaldestinationis

asubjectofmajorarguments.Theseargumentscastashadowontheimportanceofnutritionalsupplements.

Mostdoctorswilltellyouthatnutritionalsupplementscannothurt,butstopshortofendorsingthem.

Thereasonisthelackofevidencethattheactiveingredientshavebeenformulatedinthecorrectformthat

can

be

used

by

the

body.

Formoreinformation,pleasecall

Disclaimer:Likeallnutritionalsupplements,thisproductisnotintendedtodiagnose,mitigate,treatorprevent

anydisease.

+97155-5887930 or email [email protected]

www.laminine.suilt.com.ph

Documents

Background and History of Laminine