HEMATOLOGY

1. Branch of science concerned with the study of blood, blood-forming tissues and disorders associated with them

2. Connective tissue composed of a liquid extracellular matrix that dissolves and suspends various cells and cell fragments.

3. Liquid extracellular matrix of the blood4. Color when it has high O2? Low O2?5. Withdrawal of blood from a vein using a

needle and collecting tube? 6. Give one common site for venipuncture? 7. Procedure wherein blood is withdrawn from

an artery; used to determine the level of oxygen in oxygenated blood

8. WBCs are ____ dense than RBCs but ____ than blood plasma, hence, they form a very thin ____ .

9. Most of the plasma proteins are synthesized by?

10. Plasma proteins which are produced during certain immune responses?

11. 2 Reasons for higher hematocrit in males than in females?

12. A significant drop in hematocrit indicates?13. Occurs when the percentage of RBCs is

abnormally high14. Before birth, hemopoiesis occurs in the ____

of an embryo and later in the ___, ___, ____ and ____ of a fetus.

15. Becomes the primary site of hemopoiesis in the last three months before birth?

16. Red bone marrow cells which are derived from mesenchyme

17. Cells which have the capacity to develop into many different type of cells

18. Withdrawal of a small amount of red bone marrow with a fine needle and syringe

19. Removal of a core of red bone marrow with a large needle

20. Form the reticular fibers which make the stroma supporting red bone marrow cells

21. Enlarged and leaky capillaries that surround red bone marrow and fibers.

22. T or F. Formed elements do not divide once they leave red bone marrow.

23. Cells which differentiate from myeloid stem cells?

24. T or F. Progenitor cells are no longer capable of reproducing themselves and are committed to giving rise to more specific elements of blood.

25. Hormones which regulate the differentiation and proliferation of particular progenitor cells.

26. Increases the number of red blood cell precursors

27. Cells found between the kidney tubules responsible for the production of EPO

28. Stimulate proliferation of progenitor cells in red bone marrow and regulate the activities of cells involved in non-specific defenses and immune responses.

29. Artificial form of erythropoietin used in treating diminished RBC production that accompanies end-stage kidney disease

30. T or F. Hb molecules are synthesized after loss of the nucleus.

31. Ringlike non-protein pigment in Hb?32. The gaseous hormone, ______, produced

by the endothelial cells that line blood vessels, that binds to Hb and causes vasodilation

33. RBCs live only for how many days?34. Production of RBCs starts in the red bone

marrow with a precursor cell called?35. During the first weeks after birth, the ___,

not the kidneys, produces most EPO.36. T or F. Agranular leukocytes do not possess

cytoplasmic granules. 37. Describe the nucleus of a lymphocyte?38. Size of lymphocytes?39. 3 types of lymphocytes40. An increase in the number of WBCs above

10,000 per µL41. Process by which WBCs leave the

bloodstream, rolling along the endothelium, sticking to it and then squeezing into the endothelial cells?

42. Among WBCs, __________ respond most quickly respond to tissue destruction by bacteria

43. Proteins of neutrophils which exhibit a broad range of antibiotic activity against bacteria and fungi

44. Under the influence of the hormone ______, myeloid stem cells develop into

megakaryocyte-colony-forming cells that in turn develop into precursor cells called ______.

45. Replacement of cancerous or abnormal red bone marrow with healthy red bone marrow in order to establish normal blood cell counts.

46. When arteries or arterioles are damaged, the circularly arranged smooth muscle in their walls contracts immediately, a reaction called?

47. Hormone in platelets that cause proliferation of vascular endothelial cells, vascular smooth muscle fibers and fibroblasts.

48. Process of sticking of platelets to parts of a damaged blood vessel

49. Mass formed by the accumulation and attachment of a large number of platelets

50. Straw-colored liquid composed of blood plasma minus the clotting proteins

51. Gel formed when blood is drawn out of the body; consists of a network of insoluble fibrin fibers which trap formed elements

52. Process of gel formation, a series of reactions which culminates in the formation of fibrin threads

53. In the extrinsic pathway, a tissue protein called (2), leaks into the blood.

54. Endothelial cells and WBCs produce a prostaglandin called _______ that opposes the actions of thromboxane A2.

55. Blocks the action of several factors, including XII, X and II.

56. An anticoagulant produced by mast cells and basophils which combines with anti-thrombin and increases its effectiveness in blocking thrombin.

57. Autoimmune condition in which the RBCs of the fetus have been targeted and lysed by the mother’s antibodies

58. Characterized by an enlarged brain, edematous and yellow

59. Diagnostic test for HDN (Hemolytic Disease of the Newborn)

60. A condition where abnormal amounts of fluid build up in two or more body areas causing swelling

61. Group of hereditary hemolytic anemias associated with deficient Hgb synthesis

62. In HbS, glutamic acid is replaced by _____63. Piling up of too many RBCs trying to enter

small BVs64. Also known as the Kissing virus