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BIO305 Developmental BiologyInstructor: Dave Champlin
Class meets: Tuesdays and Thursdays, 8:45AM -10:00AMPrerequisite: BIO107Attendance: Attendance is required. If you miss more than about six classes you should let me know why. Required Text: Principles of Development, 4rd Edition, 2010. Lewis Wolpert, et al.
Instructor: Dr. David Champlin Office: 305B Science Building, PortlandEmail: [email protected] Office Phone: 228-8349Office Hours: My office hours will be Tuesdays and Wednesdays, 12:00 - 2:00 PM, but you can make an appointment to meet with me at just about any time. Here is a link that can help you with that: http://web1.uct.usm.maine.edu/~champlin/Advising/CalendarW.htm
Web Resources: A copy of this syllabus is available at: http://media.usm.maine.edu/~champlin/courseW.htmAt this site are copies of the exams from the previous time this course was taught. My goal will be to post the PowerPoint presentations I use in lecture at this site also as well as a recording of the lecture for one week.
The maximum number of points for the course is 520 as follows:Each is described in more detail on our course web site: http://media.usm.maine.edu/~champlin/courseW.htm review paper worth 100 pointstwo short writing assignments each worth 20 pointstwo exams each worth 100 pointscumulative final worth 100 pointsfive quizzes each worth 20 pointsfive in-class assignments each worth 20 pointsNo make-ups for missed quizzes or in-class assignments, but you can drop the lowest two scores of the ten total quizzes / assignments. Each quiz will be announced at least a week ahead of time, but the in-class assignments
won’t be announced ahead of time.
Day Date Reading Topic T 9/3 pp.216-231 (Ch. 6) C. elegans, model systems, and molecular geneticsWatch three Audio/Video handouts: 1A), 1B), and 1CTh 9/5 Ch. 1 An introduction to developmental biologyT 9/10 QUIZ 1 (covers A/V Handouts 1A, 1B, and 1C) More introduction Watch two Audio/Video handouts: Review of transcription regulation, Parts 1 and 2Th 9/12 Ch. 3 Vertebrate life cyclesT 9/17 QUIZ 2 (covers A/V Handouts 2A and 2B)
Vertebrate axes and germ layersTh 9/19 CH. 4 Vertebrate axial patterningT 9/24 More vertebrate body planTh 9/26 Ch. 5 Early patterning of vertebrate nervous systems T 10/1 EXAM 1 Chapters 1, 3, 4, and pp216-231Th 10/3 Ch. 2 Molecular development of DrosophilaT 10/8 More molecular development of DrosophilaTh 10/10 Ch. 7 Plant developmentOn Thursday, 10/10, Please bring a copy of the primary research article you have selected (or more than one if you haven’t decided) plus your notes on the article.
What is developmental biology?
What is developmental biology?
Lewis Wolpert = author of our book
What is developmental biology?
Lewis Wolpert = author of our book
"What is the one thing everyone should learn about science?" Wolpert responded:
I would teach the world that science is the best way to understand the world, and that for any set of observations, there is only one correct explanation. Also, science is value-free, as it explains the world as it is.
What is developmental biology?
BIO407 Environmental Modulation of Developmental Mechanisms
Taught every other spring. It was taught last spring.
Textbook: Scott Gilbert. 2010. Ecological Developmental Biology: Integrating Epigenetics, Medicine, and Evolution
What is developmental biology?
Maine Medical Center Research Institutein Scarborough
Research internshipsSummer fellowship program
What is developmental biology?
What is developmental biology?
What is developmental biology?What is developmental biology?
You have made your way from worm to man, and much within you is still worm. Friedrich Nietzsche, 1883, from Also Sprach Zarathustra
Caenorhabditis elegansC. elegans
Caenorhabditis elegans = C. elegans nematode
The 2002 Nobel Prize in Medicine was awarded to these scientists for the use of C. elegans to understand programmed cell death (PCD).
A fertilized nematode egg and early embryos as viewed with Nomarski optics = Differential Interference Contrast (DIC).
As each C. elegans worm grows from the fertilized egg, it has an invariant cell lineage.
