Biochem Post Test

7/23/2019 Biochem Post Test

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Biochemistry

Choose the best answer:

___1. Which among the following lipoproteins is inversely related to the incidence of coronary

atherosclerosis?A. Chylomicrons B. HDL C. LDL D. LDL

___!. "n the sh#ttle of mitochondrial acetyl coen$yme A to the cytosol for fatty acid synthesis% inwhich step generates &AD'(?

A. )*aloacetate + acetyl coen$yme Acitrate

B. )*aloacetate malate

C. Malate pyruvate

D. 'yr#vateo*aloacetate

___,. -he lipoprotein that serves to transport triacyglycerol from the liver to the

different e*trahepatic tiss#es.A. Chylomicrons . (DL C. LDL D. VLDL

___/. "n the following steps in 0etone bodies metabolism% &AD( is generated in:A. Acetoacetateacetone

B. Acetoacetatebeta hydro*yb#tyrate

C. Acetoacetyl coen$yme A + acetyl coen$yme A(2 CoA

D. Beta hydroxybutyrate acetoacetate

____3. (#man body synthesi$e cholesterol de novo from acetyl coen$yme A. Cholesterolsynthesis occ#rs in which of the following organelles?

A. Cytosol . endoplasmic retic#l#m C. mitochondria D. ribosomes

___4. Which among the following conditions is characteri$ed by abnormal acc#m#lation ofgalactocerebroside in the affected tiss#es?

A. 5arber6s disease . 5abry6s disease C. Krabbes disease D. 2a#cher6s

___7. Which of the following lipoproteins has the highest triacylglycerol content?A. Chylomicrons . (DL C. LDL D. LDL

___8. 9etone bodies maybe synthesi$ed from fatty acids by which of thefollowing organs orcells?

A. 0eletal m#scle B. liver C. 0idney D. erythrocytes

___;. pontaneo#s decarbo*ylation of acetoacetate res#lts in the formation of:A. Acetone . acetyl coen$yme A C. ,or site of fatty acid synthesis.A. ammary gland B. liver C. adipose tiss#e D. 9idney

___11. Which among the following is acc#m#lated in tiss#es of patient with -ay


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___1/. " n the complete o*idation of one 1@ mole of palmitic acid to C)!and (!)% the totaln#mber of A-' generated is:

A. 1! . !/ C. "#" D. 1!;

___13. Which of the following is a C___17. Which among the following is an essential re#irement for triacyglycerol synthesis inthe adipose tiss#e?

A. Adrenaline . cortisol C. gl#cagon D. insulin

___18. Which among the 0etones bodies is not a so#rce of f#el in the e*trahepatic tiss#es li0ethe heart m#scle?

A. Acetoacetic acid B. acetone C. beta


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___!7. Which is considered as transcriptionally active chromatin

A. euchromatin. heterochromatinC. constit#tive chromatinD. telomeres

___!8. -his is the noncoding intervening se#ence.

A. e*onB. intronC. 0inetochoreD. telomeres

___!;. -his is the en$yme responsible D&A #nwinding d#ring replication

A. D&A ligaseB. HelicaseC. D&A polymeraseD. -opoisomerase

___,=. B#0aryotic &A polymerase "" synthesi$es:

A. r&AB. m)*A

C. t&AD. sn &A

___,1. Which one is responsible for splicing reactions of m&A

A. +snurp,. ibo$ymeC. &A polymeraseD. D&A polymerase

___,!. 'art of D&A template where transcription is to commence.

A. promoter. repressorC. enhancerD. terminator

___,,. -he genetic code is characteri$ed as:

A. non


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C. intronsD. e*ons

___,4. Complementary D&A copies of the pop#lation of m&As in a tiss#e.

A. 2enomic D&A libraryB. cD*A libraryC. intronsD. e*ons

___,7. -he entire collection of e*pressed m&As in an organism.

A. &A clone. cD&A libraryC. genomic D&A libraryD. transcriptome

_C__,8. #tation of this genes will lead to loss of the integrity of the genome:

A. )ncogenes . -#mor s#ppressor genes C. #tator genes D. protooncogenes

___,;. #tation of this gene confer chemoresistance in cancer:

A. p . p3, C. ras gene D. mismatch repair gene

___/=. (#man papilloma viral infection ca#ses overe*pression of B4 which facilitates the

Degradation of:

A. p . p3, C. m#tator gene D. protooncogene D. AC

_____/1. torage molec#le of genetic information:

A. D&A . &A C. Both D. &either

_____/!. &A and D&A differ from each other:

A. "n D&A% the n#cleotides r#n 36 to ,6 direction. "n &A% the s#gar is lin0ed to the base by an &


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____3=. Which form is favored at low h#midity?

A. A%D*A .


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A. 'roteins that are important in metabolic reg#lation are generally short


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A. 2lycine

. 'roline

C. -hreonine

D. -ryptophan

8. 9yrosine

____71. Among the following amino acids% which one is p#rely 0etogenic?

A. "sole#cine

B. Leucine

C. 'henylalanine

D. -hreonine

B. -ryptophan

____7!. Frea is the ma>or pathway of nitrogen e*cretion in h#mans. "t is synthesi$ed in the :

A. rain. "ntestine

C. 9idney

D. Liver

B. 0eletal m#scle

____7,. Among the intermediates in #rea cycle% which one provides the lin0age of #rea cycle

and the citric acid cycle?

A. Alpha 0etogl#tarate

. Aspartate

C. :umarateD. alate

B. )*aloacetate

____7/. Amino acid prec#rsor of serotonin

A. Alanine

. Aspartate

C. 9ryptophan

D. ethionine

B. -yrosine

____73. Which of the following is a non essential amino acid?

A. Le#cine

B. 9yrosine

C. Lysine

D. ethionine

B. aline

____74. Anaerobic glycolysis prod#ces how many moles of A-' per mole of gl#cose?

A. ; . 4 C. 8 D. 1! B. !/

____77. ate limiting en$yme and the ma>or reg#latory en$yme in glycolysis:

A. -riose phosphate isomerase

. 2lyceride ,


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A. &yruvate dehydroenase

. "socitrate dehydrogenase

C. Alpha


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_____;=. "t is an amphibolic pathway and regarded as the final common pathway of

metabolism:

A. Bmbden

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Biochem Post Test