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1 Updated FA2014 Biology Program Science & Health Science Division Biology 213 Syllabus Microbiology B R O O K D A L E C O M M U N I T Y C O L L E G E

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Updated FA2014 Biology Program

Science & Health Science Division

Biology 213 Syllabus

Microbiology

B R O O K D A L E C O M M U N I T Y C O L L E G E

Syllabus

2

REQUIRED MATERIALS: Foundations in Microbiology, Talaro & Chess, 9

th edition, 2014

Laboratory Manual: Microbiology Fundamentals, Obenauf and Finazzo, 2013 (Packaged and available in BCC bookstore – ISBN

1259349179)

Photographic Atlas for Laboratory Applications in Microbiology, Chess, 2012 (Optional and included in above package at no

additional cost)

ADDITIONAL TIME REQUIREMENT:

COURSE LEARNING OUTCOMES: • Demonstrate knowledge of pathogenic microorganisms.

• Apply the scientific method in a laboratory research project in the isolation and identification of unknown microorganisms.

• Demonstrate knowledge of how chemotherapy, immunology, and serology are used to combat pathogens.

(Mathematical/Scientific Reasoning/Information Literacy)

COURSE CONTENT: Unit One: Introduction to Microbiology and Taxonomy

Unit Two: General Characteristics and Representative Examples of Prokaryotic & Eukaryotic Organisms, & Viruses

Unit Three: Microbial Metabolism, Ecology, & Growth

Unit Four: Microbial Genetics

Unit Five: Antimicrobial Actions

Unit Six: Microbe-Human Interactions Unit Seven: Survey of Microorganisms of Medical Importance

GRADING STANDARD: Active and frequent participation in each chapter is required for optimum performance in this course. Students will be assessed based

on their participation and performance in class and laboratory:

Lecture exams and quizzes: 75%

Laboratory assignments, quizzes, technique evaluation, practical exams: 25%

CODE: BIOL 213 TITLE: Microbiology

DIVISION: Science/Health Science DEPARTMENT: Biology

COURSE DESCRIPTION: The biology of pathogenic microorganisms will be stressed, emphasizing their microscopic and molecular

aspects. Students will describe, in detail, the relationship existing between the host-parasite complex during the diseased state. They

will also become acquainted with those characteristics which endow certain microbes with a pathogenic nature. Students will be able

to list and characterize various pathogenic bacteria, viruses, and eukaryotic parasites (including fungi, algae, protozoa, and helminths).

Isolation and identification techniques in microbiology will be mastered by the student in the laboratory. The role of chemotherapy,

immunology and serology used to combat pathogens will be examined thoroughly. Finally, the homeostatic defense mechanism of the

body, especially those against invading microorganisms, will be discussed in great detail.

PREREQUISITES: A grade of “C” or higher in BIOL 102 or BIOL 112.

COREQUISITES: None

CREDITS: 4 LECTURE HOURS: 3 LAB HOURS: 3

Syllabus

3

A student must have an average of 65% or higher for the classroom component and an average of 65% or higher for the

laboratory component of the course in order to earn a passing grade for the course.

Upon completion of the course, grades will be assigned as follows:

A = 92 – 100%

A- = 89 - 91% C+ = 76 – 78%

B+ = 86 – 88% C = 70 – 75%

B = 82 – 85% D = 65 – 69%

B- = 79 - 81% F = <65%

Unit examination results will be reported as the grade assigned by the faculty calculated to the first

decimal place. These grades will be weighed according to course grading policy. In calculating the course

grade, 0.5 will round up to the next numerical grade and 0.4 will round down to the next lower numerical

grade.

A grade of C or higher is required in all prerequisite courses. Career studies courses must have a grade of C or higher to count toward

the Mathematics / Science Program – Biology Option.

Students are permitted to withdraw from the course without penalty until approximately 80% of the semester is complete. Please see

term schedule for the exact deadline.

At the end of the semester, application for an Incomplete may be made if a student with proper documentation needs to complete no

more than one lecture exam and/or one laboratory practical. The granting of an Incomplete is at the discretion of the instructor.

(Please see Instructor’s syllabus for additional Grading Policies.)

DEPARTMENT POLICIES: Attendance during class and laboratory sessions is strongly recommended for optimum performance in biology courses.

Lecture exams will be given in class.

Laboratory practicals will be given during laboratory sessions, in accordance with schedules provided by the learning assistants.

Exams and practicals must be taken at the times designated by the instructor or learning assistant. A student who misses a lecture

exam or laboratory practical must provide prior notification and proper documentation in order to take the exam or laboratory

practical. The acceptance of said prior notification and proper documentation will be determined by the instructor.

Documentation must be provided within one week of the student’s return to the classroom for a make-up exam or laboratory practical

to be scheduled. A student who is unable to provide proper documentation for a missed exam or laboratory practical will be given a

grade of zero for that exercise. Students may not re-take exams or laboratory practicals on which they perform poorly.

Requirements for the completion of laboratory are listed in the laboratory responsibility sheets for individual courses. Requirements

for course completion are listed in individual instructor syllabi.

COLLEGE POLICIES:

For information regarding:

♦ Brookdale’s Academic Integrity Code

♦ Student Conduct Code

♦ Student Grade Appeal Process

Please refer to the STUDENT HANDBOOK AND BCC CATALOG.

NOTIFICATION FOR STUDENTS WITH DISABILITIES: Brookdale Community College offers reasonable accommodations and/or services to persons with disabilities. Students with

disabilities who wish to self-identify, must contact the Disabilities Services Office at 732-224-2730 or 732-842-4211 (TTY), provide

appropriate documentation of the disability, and request specific accommodations or services. If a student qualifies, reasonable

accommodations and/or services, which are appropriate for the college level and are recommended in the documentation, can be

approved.

ADDITIONAL SUPPORT/LABS: BIOL 213 course and laboratory resources are available in CANVAS, Brookdale’s Learning Management System, available via the

Brookdale website: www.brookdalecc.edu

Syllabus

4

Independent Study Laboratory (Open Lab) – MAS 041 – is available to students enrolled in this biology course. Students use this

lab to review lab materials, and to get help with course materials from learning assistants that staff the lab.

Brookdale Biology Department course and program information is available on the Biology Department website:

http://sites.brookdalecc.edu/home/science-health-sciences/biology/

Syllabus

5

BIOL 213 Microbiology # 1 of 7 Units 4 Course No. Title Credits

Name of Unit: INTRODUCTION TO MICROBIOLOGY AND TAXONOMY

Textbook: Foundations in Microbiology, 9th edition, Chapter 1

Method of Evaluation: Lecture Exams and Quizzes, Laboratory Practicals, Quizzes, and Project

Objectives Recommended Learning Experiences

The student will be able to: Class Discussion Textbook Readings:

1. Define microbiology. page 2

2. Compare and contrast microorganisms: viruses, pages 5-6 bacteria, protozoa, algae, fungi and helminths

3. Describe units of measurement used for microorganisms. page 7

4. Identify various branches in the field of microbiology. pages 2, 3, 4, 9

5. Describe the significance of microorganisms: pages 8,11

-medically, environmentally and commercially/economically

6. Recognize the contributions made by scientists to the field of of microbiology, to include: pages 11-18

Robert Hooke Paul Ehrlich Anton van Leeuwenhoek Alexander Fleming Francesco Redi Ernst Chain & Howard Florey Louis Pasteur Selman Waksman Robert Koch Rebecca Lancefield Joseph Lister Avery, MacLeod & McCarty Edward Jenner James Watson & Frances Crick Hans Christian Gram Nathans, Smith & Arber Elie Metchnikoff

7. Describe the contributions of Carolus Linnaeus (the pages 19, 23, 24

“Father of Taxonomy”), Robert Whittaker, and Carl Woese to the field of taxonomy.

8. Describe the current system of classification in biology: pages 19, 22, 23 3

domains 5 kingdoms further categories

9. Describe the classification of prokaryotes and viruses, to pages 110-113, 166-168 include the criteria used to classify microorganisms.

10. Describe classification systems of prokaryotic domains in

Bergey’s Manual of Systematic Bacteriology 2nd ed. pages 110-113

Syllabus

6

11. Describe the classification of eukaryotic organisms to include criteria used for each group. pages 141-143, 144-148, 152-153

12. Correctly use the universal system of scientific naming of pages 19-21

organisms - binomial nomenclature

13. Demonstrate the ability to use dichotomous keys in the identification of microorganisms.

Syllabus

7

BIOL 213 Microbiology # 2 of 7 Units 4 Course No. Title Credits

Name of Unit: GENERAL CHARACTERISTICS AND REPRESENTATIVE EXAMPLES OF PROKARYOTIC AND EUKARYOTIC ORGANISMS, AND VIRUSES

Textbook: Foundations in Microbiology, 9th edition, Chapters 4, 5, & 6

Method of Evaluation: Lecture Exams and Quizzes, Laboratory Practicals, Quizzes, and Project

Objectives Recommended Learning Experiences

The student will be able to: Class Discussion Textbook Readings:

1. Compare properties and cell structures in prokaryotes pages 89,133, Table 5.2

and eukaryotes.

2. Describe sizes, shapes, and arrangement of prokaryotes. pages 105-108, 114

3. Describe the following prokaryotic cell structures and their pages 90-105 related functions:

a. Structures external to cell wall

1. Flagella pages 91-93 2. Axial Filaments (periplasmic flagella) page 93-94 3. Pili and Fimbriae pages 94 4. Glycocalyx page 94, 96

a. capsule b. slime layer

b. Cell wall pages 72-73, 97-100 1. Functions 2. Composition & characteristics 3. Gram stain 4. Negative Stain

c. Structures internal to cell wall pages 100-105-96 1. Plasma membrane 2. Cytoplasm 3. Nucleoid – chromosome 4. Plasmid 5. Ribosomes 6. Inclusions 7. Endospores

4. Describe biofilms and explain their significance page 95-96

5. Survey prokaryotic groups with unusual characteristics pages 113-117

6. Describe the history of eukaryotic cells including the

endosymbiotic hypothesis/theory pages 123-125

Syllabus

8

7. Review eukaryotic cell structures and their functions. pages 125-132 -external -internal

8. Describe the basic characteristics of the Kingdom Fungi

including general types of cells and organisms, structure, and nutrition; differentiate between yeasts and molds, types of fungal spores; importance in medicine, nature and industry. pages 134-143

9. Discuss general characteristics of algae, and importance . pages 143-150

10. Discuss general characteristics, basic morphology of major

groups of parasitic helminths, life cycles, reproduction pages 151-153

11. Describe viral origin, history, characteristics, structure, morphology, and importance. pages 157-166

12. Describe viral multiplication including

-multiplication of animal viruses (DNA and RNA); damage to host cell pages 168-172

-bacteriophage multiplication, lysogeny pages 173-175 13. Discuss cultivation, detection, and treatment of viruses. pages 175-179

14. Describe nonviral infectious particles including prions and

viroids. pages 179-180

Syllabus

9

BIOL 213 Microbiology #3 of 7 Units 4 Course No. Title Credits

Name of Unit: MICROBIAL METABOLISM, ECOLOGY, AND GROWTH

Textbook: Foundations in Microbiology, 9th edition, Chapters 2, 7, & 8

Method of Evaluation: Lecture Exams and Quizzes, Laboratory Practicals, Quizzes, and Project

Objectives Recommended Learning Experiences

The student will be able to: Class Discussion Textbook Readings:

1. Review composition, properties, and functions of macromolecules. pages 41-54

2. Describe major categories of nutritional types among organisms. pages 187-192

3. Define requirements for microbial growth including pages 186-202; 39-40 -Micronutrients, macronutrients, essential nutrients -Physical and Chemical Requirements

Carbon, oxygen, water, phosphate, nitrogen, sulfur Temperature Osmotic Pressure pH

4. Define bacterial growth. pages 208-209

5. Define generation time or doubling time in prokaryotes page 208

6. Name and describe the stages in the bacterial growth curve. pages 210-211

7. Discuss direct and indirect methods of analyzing bacterial population

growth. pages 211-213

8. Discuss the range of ecological associations among microorganisms and interrelationships between microbes and humans. pages 202-206

9. Describe the development and significance of biofilm association. pages 206-207

10. Define metabolism. Describe the following: pages 218-231

-catabolism and anabolism -role of ATP -metabolic pathways -enzymes and enzyme action -factors influencing enzymatic activity -oxidation-reduction reactions -generation of ATP

11. Demonstrate an understanding of the following metabolic pathways pages 231-246; Appendix A

In microorganisms:

Syllabus

10

Carbohydrate catabolism Glycolysis Aerobic Respiration

Bridge reaction (Transition or Preparatory step) Krebs Cycle Electron Transport Chain

Anaerobic Respiration Fermentation reactions

Lipid and protein catabolism Anabolic pathways

Syllabus

11

BIOL 213 Microbiology # 4 of 7 Units 4 Course No. Title Credits

Name of Unit: MICROBIAL GENETICS

Textbook: Foundations in Microbiology, 9th edition, Chapters 2, 9, & 10

Method of Evaluation: Lecture Exams and Quizzes, Laboratory Practicals, Quizzes, and Project

Objectives Recommended Learning Experiences

The student will be able to: Class Discussion Textbook Readings:

1. Describe the structure of the nucleic acids – DNA & RNA pages 52-53, 257, 259

2. Describe the relationships among DNA, gene, genome, pages 257-258

chromosome, genotype, phenotype.

3. Compare the genome of prokaryotes to that of eukaryotes. pages 258-259

4. Describe the process of DNA replication in prokaryotes. pages 259-264

5. Describe the process of RNA replication in prokaryotes. pages 264-268, 271

6. Describe the process of protein synthesis in prokaryotes. pages 268-271

7. Explain the operon model of gene expression. Describe pages 274--276 regulation of gene expression in bacteria by induction and repression.

8. Define mutation. Describe types of mutations and pages 277-281

categories of mutagens.

9. Compare the mechanisms of genetic recombination in bacteria. pages 281-286 Differentiate between horizontal and vertical gene transfer.

10. Describe the functions of vectors (plasmids and phages) pages 102, 257, 285-286, 303-304, 373

and transposons.

11. Compare replication strategies in DNA and RNA viruses. pages 287-288

12. Describe methods and applications of genetic engineering. pages 294-298, 300-301, 304-306, 307-308, 309-311, 313-315

Syllabus

# 5 of 7 Units BIOL 213 Course No.

Microbiology Title

4 Credits

Name of Unit: ANTIMICROBIAL ACTIONS

12

Textbook: Foundations in Microbiology, 9th edition, Chapters 11 & 12

Method of Evaluation: Lecture Exams and Quizzes, Laboratory Practicals, Quizzes, and Project

Objectives Recommended Learning Experiences

The student will be able to: Class Discussion Textbook Readings:

1. Define and differentiate among the major terms for microbial pages 322-325

control including

• Sterilization

• Disinfection

• Antisepsis

• Sanitation

• Degerming

2. Identify factors that influence effectiveness of antimicrobial agents or methods. pages 322-324

3. Identify the targets of antimicrobial control agents. pages 327-328

4. Describe the actions and effects of physical and chemical

agents or methods used to control microbial growth. pages 329-348

5. Describe antimicrobial drugs and distinguish between antibiotics, synthetics, and semisynthetics pages 354-356, Table 12.3

6. Identify the primary sources if antibiotics. pages 354, 356

7. Identify characteristics of ideal antimicrobial drugs. page 377

8. Describe the mechanisms of action of antimicrobial drugs. pages 356-360

9. Identify commonly used antibacterial drugs according to mode

of action. page 357-360

10. Identify the modes of action and representative examples of major antimicrobial groups including: pages 361-371

• Antibacterial drugs

• Antifungal drugs

• Antiparasitic drugs

• Antiviral drugs

11. Describe the mechanisms of drug resistance pages 371-376

Syllabus

12. Identify side effects of antimicrobial drug use in humans. pages 375-378

13

13. Discuss the effects of combining antimicrobial drugs. pages 204-205, 354-355, 379 14. Describe tests for microbial susceptibility to antimicrobial

drugs. pages 380-382

Syllabus

# 6 of 7 Units BIOL 213 Course No.

Microbiology Title

4 Credits

Name of Unit: MICROBE-HUMAN INTERACTIONS

14

Textbook: Foundations in Microbiology, 9th edition, Chapter 13

Method of Evaluation: Lecture Exams and Quizzes, Laboratory Practicals, Quizzes, and Project

Objectives Recommended Learning Experiences

The student will be able to: Class Discussion Textbook Readings:

1. Define the terms associated with infectious diseases. pages 389-390

2. Define normal microbiota. Distinguish between resident and

transient microbiota. Identify sites that harbor normal microbiota and those that are microbe-free. pages 389-397

3. Discuss the major factors in the development of an infection

including entry, adhesion, multiplication, effects. Compare endotoxins and exotoxins. pages 397-406

4. Describe the clinical stages of disease. pages 406-407

5. Discuss the patterns of infection and distinguish between

localized and systemic, focal and mixed, primary and secondary, endogenous and exogenous infections. pages 399, 407-408

6. Use correct terminology to explain the manifestations (signs

and symptoms) of infections and inflammation. page 408

7. Describe the transmission of disease by identifying reservoirs of infection, distinguishing between types of vectors, and types of carriers. Define zoonoses. pages 410-412

8. Describe the transmission of disease. Distinguish between

communicable, noncommunicable, and contagious diseases. pages 413-415

9. Define nosocomial infections and explain their significance. pages 418-420

10. Define epidemiology and explain the major methods of tracking infections and diseases in a population. pages 415-418

11. Differentiate among the patterns of disease outbreaks

according to frequency, number, location, and duration. pages 407-408, 416-418

12. Demonstrate a thorough understanding of Koch’s Postulates. pages 17, 18, 419

Syllabus

# 7 of 7 Units BIOL 213 Course No.

Microbiology Title

4 Credits

Name of Unit: SURVEY OF MICROORGANISMS OF MEDICAL IMPORTANCE

15

Textbook: Foundations in Microbiology, 9th edition, Chapters 17, 18, 19, 20, 21, 22, 23, 24, & 25

Method of Evaluation: Lecture Exams and Quizzes, Laboratory Practicals, Quizzes, and Project

Objectives Recommended Learning Experiences

The student will be able to: Class Discussion Textbook Readings:

1. Summarize common procedures used for identifying pathogens and diagnosing infections. pages 521-538

2. Describe each of the following bacteria to include:

• general characteristics: structure, arrangement, staining properties

• metabolic and pathogenic properties

• diseases caused in humans and locations in body

A. Gram-Positive cocci 1.) Staphylococcus pages 544-551 2.) Streptococcus pages 552-561 3.) Enterococcus pages 545, 557

B. Gram-Negative cocci

1.) Neisseria pages 562-568 2.) Moraxella page 569

C. Gram-Positive endospore forming bacilli

1.) Bacillus pages 575-578 2.) Clostridium pages 579-585

D. Gram-Positive Regular Non-spore-forming bacilli

1.) Listeria pages 586-587

E. Gram-Positive Irregular Non-spore-forming bacilli 1.) Corynebacterium pages 588-589 2.) Propionibacterium page 589

F. Mycobacterium: Acid-Fast Bacilli

1.) M. tuberculosis pages 589-595 2.) M. leprae pages 595-598

G. Actinomycetes: Filamentous bacilli 1.) Actinomyces pages 598-599 2.) Nocardia page 599

Syllabus

H. Gram-Negative Aerobic Bacilli

16

1.) Pseudomonas pages 600-608 2.) Burkholderia, Acinetobacter pages 256, 288, 569, 609 3.) Brucella page 609 4.) Francisella page 610 5.) Bordetella pages 610-611 6.) Legionella pages 612-613

I. Gram-Negative Facultative Anaerobic Bacilli

- Family Enterobacteriaceae pages 613-626 1.) Coliform Enteric Organisms: E. coli pages 617-619

Serratia Klebsiella Enterobacter Citrobacter

2.) Noncoliform Enteric Organisms: Proteus page 620

Providencia Morganella

3.) True Enteric Pathogens: Salmonella pages 620-626

Shigella Yersinia enterocolitica

4.) Nonenteric Organism: Yesinia pestis pages 619-621

-Family Pasteurellaceae 1.) Pasteurella page 626 2.) Haemophilus pages 627-628

J. The Spirochetes pages 634-642

1.) Treponema pages 634-638 2.) Leptospira pages 639-640 3.) Borrelia pages 640-642

K. Curviform Gram-Negative Bacteria pages 643-647

1.) Vibrio pages 643-646 2.) Campylobacter page 646 3.) Helicobacter pages 646-647

L. Order Rickettsiales pages 648-653

1.) Rickettsia pages 649-651 2.) Ehrlichia pages 651-652 3.) Anaplasma page 651 4.) Coxiella page 652 5.) Bartonella pages 652-653

M. Family Chlamydiaciae pages 653-656

1.) Chlamydia pages 653-655 2.) Chlamydophila pages 655-656

Syllabus

17

N. Cell-Wall-Deficient Bacteria 1.) Mycoplasma pages 656-657

3. Describe Fungi of Medical Importance to include: pages 667-672

• general characteristics

• degree of pathogenicity

• nature of infection (primary or secondary; true or opportunistic)and infecting form

• habitat and geographic location

• metabolic and pathogenic properties

• organization of fungal diseases (mycoses)

• characteristics of common antifungal drugs

A. Systemic Fungal Pathogens 1.) Histoplasma pages 143, 668, 673-674, 682 2.) Coccidioides pages 143, 668, 675-676 3.) Blastomyces pages 143, 668, 677-678

B. Subcutaneous Fungal Pathogens

1.) Sporothrix pages 668. 678-679

C. Cutaneous Fungal Pathogens (Dermatophytes) 1.) Tricophyton pages 143, 668, 680-683 2.) Microsporum pages 143, 668, 680-683 3.) Epidermophyton pages 143, 668, 680-683

D. Opportunistic Fungal Pathogens 1.) Candida pages 143, 366, 668, 684-685 2.) Cryptococcus pages 143, 662, 668, 686 3.) Pneumocystis pages 593, 668, 686-687 4.) Aspergillus pages 660, 668, 687-688

4. Define terms associated with parasitology pages 151, 696-697

5. Describe Parasites of Medical Importance to include pages 696-725

• general characteristics of each group of parasitic pathogens

• portals of entry, habitat, geographic location

• diseases caused in humans and location in the body

• antiparasitic drugs of choice

A. Protozoan Pathogens 1.)

Amoeboid Protozoa a. Entamoeba pages 149, 150, 697-700 b. Naegleria pages 149, 150, 700

2.) Ciliate Protozoan

a. Balantidium coli pages 148, 149, 700-701

Syllabus

18

3.) Flagellate (Mastigophoran) Protozoa a. Trichomonas pages 148, 149, 701-702 b. Giardia pages 148, 149, 403,702 c. Trypanosoma pages 148, 149, 403, 702-705

4.) Apicomplexan Protozoa a. Plasmodium pages 148,149, 688, 707-710 b. Toxoplasma pages 148, 149, 710-711 c. Cryptosporidium pages 148,149, 150, 678-679, 686, 711-712 d. Cyclospora pages 148, 149, 151, 712 e. Babesia pages 148, 712

B. Helminthic Pathogens pages 713-722

1.) Nematodes (Roundworms) pages 713, 714, 717 a. Ascaris pages 122, 714, 717 b. Trichuris trichiura pages 704, 707-708 b. Enterobius pages 714, 718 c. Trichinella pages 714, 719-720 d. Wuchereria pages 714, 721 e. Onchocerca pages 714, 721 f. Loa loa pages 714, 721 g. Necator americanus pages 714, 718-719 h. Dracunculus pages 714, 722

2.) Trematodes or Flukes (Flatworms) pages 722-725

a. Schistosoma pages 714, 722-723 b. Fasciola pages 714, 723 c. Paragonimus pages 714, 723

3.) Cestodes or Tapeworms (Flatworms) pages 714, 705, 714-715

a. Taenia solium, T. saginata pages 714, 724-725 b. Diphyllobothrium page 714 c. Echinococcus page 718

6. Differentiate among the Arthropod vectors of infectious

disease pages 725-727 7. Describe DNA and RNA Viruses that infect humans. Discuss

• general characteristics, identification, diagnosis, classification, effects of infection on host cells

• diseases and location in the body pages 734-793

A. Enveloped Double-stranded DNA Viruses pages 737-747

1.) Poxviruses (Poxviridae) pages 167, 737-739 a. Variola, Vaccinia pages 167, 737-739

Syllabus

19

2.) Herpesviruses (Herpesviridae) pages 739-747 a. Herpes simplex virus (HSV-1 and HSV-2) pages 167, 735, 739-743 b. Varicella-Zoster Virus (VZV) pages 167, 735, 743-744 c. Epstein-Barr Virus (EBV) pages 735, 745-747 d. Cytomegalovirus (CMV) pages 167, 735, 745 e. Herpesviruses 6, 7, 8 pages 735, 747

3.) Hepadnaviruses (Hepadnaviridae) pages 167, 735, 748-751

a. Hepatitis B Virus (HBV) pages 167, 735, 748-751

B. Nonenveloped Double-stranded DNA Viruses pages 751-753

1.) Papillomaviruses (Papillomaviridae) pages 167, 752-753 a. Human Papillomavirus (HPV) pages 167, 752-753

C. Nonenveloped Single-stranded DNA Viruses page 754

1.) Parvoviruses (Parvoviridae) pages 167, 754

a. Parvovirus (Erythrovirus) pages 167, 754 D. Enveloped Segmented Single-stranded RNA Viruses

1.) Orthomyxoviruses (Orthomyxoviridae) (ss-) pages 167, 760-765

a. Influenza virus A, B, C pages 167, 760-765

2.) Bunyaviruses (Bunyaviridae) (ss-) pages 167, 748, 765 a. Hantavirus pages 167, 761, 765-766

E. Enveloped Nonsegmented Single-stranded RNA Viruses

1.) Paramyxoviruses (Paramyxoviridae) (ss-) pages 167, 767

a. Paramyxovirus (parainfluenza virus types 1-5 and mumps virus) pages 167, 761, 767-768

b. Morbillivirus (measles/rubeola virus) (ss-) pages 167, 761,770 c. Pneumovirus (respiratory syncytial virus (RSV) (ss-) pages 167, 761,770

2.) Rhabdoviruses (Rhabdoviridae) (ss-) pages 168, 770-772

a. Lyssavirus (Rabies virus) pages 168, 761, 770-772

3.) Filoviruses (Filoviridae) (ss-) page 167, 748 a. Ebola virus pages 167, 751, 766 b. Marburg virus pages 167, 753

4.) Coronaviruses (Coronaviridae) (ss+) pages 168, 772

a. Coronavirus /Severe Acute Respiratory Syndrome Virus (SARS) (ss+) pages 168, 761, 766, 773-774

5.) Togaviruses (Togaviridae) (ss+) pages 167, 761, 773-774

a. Rubivirus (Rubella/ German Measles)) pages 167, 478, 761, 773-774

Syllabus

20

b. Alphavirus (Yellow Fever, Eastern & Western Equine Encephalitis, Chikungunya virus) pages 167, 761

6.) Flaviviruses (Flaviviridae) (ss+)

a. Flavivirus (Dengue Fever virus, West Nile Fever virus, Hepatitis C virus (HCV)) pages 167, 321, 348, 748, 761, 766, 774

7.) Picornaviruses (Picornaviridae) (ss+) pages 167, 772-780

a. Enterovirus (Poliovirus, Coxsackie virus) pages 11, 167, 512, 787, 789-790 b. Hepatovirus (Hepatitis A virus (HAV)) pages 167, 748, 761, 790 c. Rhinovirus (Common Cold virus) pages 167, 198, 761, 787, 790-791

8.) Caliciviruses (Caliciviridae) (ss+)

a. Calicivirus / Norovirus (Norwalk agent) pages 167, 786, 791

F. Double-stranded Nonenveloped RNA viruses

1.) Reoviruses (Reoviridae ) pages 165, 167, 791-792 a. Rotavirus pages 167, 481, 761, 791-792

G. Double-stranded Enveloped RNA viruses produce DNA

using Reverse transcriptase pages 777-786

1.) Retroviruses (Retroviridae) pages 178, 288, 777-786 a. Lentivirus (HIV) pages 166, 168, 777 b. Oncornavirus (Human T-Cell Lymphotropic virus I)

(HTLV-1) (Leukemia) pages 168, 172, 287, 736-737 8. Define Arbovirus; describe the pathology and mode of

Transmission of arboviruses pages 774-777 9. Explain the pathogenesis, transmission, and epidemiology

of prion diseases pages 179-180, 324, 761, 792-793