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Biomolecules and Cells
Elements of Life
• A few major elements make up virtually all living things
• Roughly 96% of an organism’s mass (including humans) is composed of just 4 elements– Oxygen– Carbon– Hydrogen– Nitrogen
Elements of Life
• Together, these 4 elements combine to make up almost all of the major organic and inorganic compounds in our bodies.
• The need for more of these elements to grow, reproduce, and make and use energy underlies almost all of the competition and struggles of life
Elements of Life
• Organic compounds always contain 1 key element ?
Elements of Life
• Organic compounds always contain 1 key element ?– Carbon
Though not all carbon containing compounds are organic
Elements of Life
• Important Inorganic Compounds in the body?
Elements of Life
• Important Inorganic Compounds in the body?– H2O (typically 60-80% of living things)
– CO2
– Fe– Minerals (Bones, teeth)– Salts and Ion Electrolytes
Elements of Life
• Important Organic Compounds in the body?
Elements of Life
• Important Organic Compounds in the body?
• Key Organic compounds typically fall under classes of Macromolecules:– Proteins– Nucleic Acids– Carbohydrates– Lipids
Elements of Life- Proteins
• Proteins are long, heavy organic compounds that have a function and whose function depends on the 3-D structure of the molecule(s)
• Proteins are polymers (polypeptides) made up of amino acid monomers bonded together to form a chain
Elements of Life- Proteins
• Proteins consist primarily of C,H, O, & N– Also contain S (only macromolecule group that does…)
• The protein structure is determined by the sequence of amino acids, which is determined by the genetic sequence of DNA.
• This causes the protein to fold in certain ways to give the protein its 3-D conformation
• Proteins are made using RNA in a process called Translation
Elements of Life- Proteins
• Protein functions include:– Structural support for cells and tissues– Energy production, storage, and consumption
(Metabolism)– Signaling• Hormones, signal peptides, immune system
– Enzymes• Chemical catalysts that increase reaction speed, or help
the reaction to occur in the first place
Elements of Life- Nucleic Acids
• Nucleic Acids chains consist of nucleotides which consist of:– Nitrogenous Base (A,C,G,T)– Sugar molecule (deoxyribose or ribose- hence the
name)– Phosphate backbone (negatively charged)
• Genetic information encoded in DNA• Expressed from DNA to RNA in Transcription
Elements of Life- Nucleic Acids
• Nucleic Acids consist mainly of C,H,O,N and P due to the phosphate backbone
• In humans and other Eukaryotes, the DNA is stored in the cell inside a membrane bound organelle called the Nucleus
Elements of Life- Carbohydrates
• Carbohydrates are hydrates of Carbon. This means they have the general formula (CH2O)n
• Consist only of C,H, and O. Lack the other elements except in rare cases
• Exist as monomers (single sugars) or polymers of sugars (disaccharides and polysaccharides)– Disaccharides have two monomers (Sucrose)– Polysaccharides have many monomers (Starch)
Elements of Life- Carbohydrates
• Cellulose is the most abundant organic compound on Earth.– Consists of glucose molecules bound together to
form a polymer– Forms wood, bark, leaves, and other fibrous
structures in plants
• Why isn’t it easily digested like glucose or other starches?
Elements of Life- Carbohydrates
Image from FAMU
Elements of Life- Lipids
• Diverse group of compounds that share the main characteristic of being non-polar, hydrophobic
• Main functions are in cell membranes, energy storage, and steroid hormones
• Consist primarily of C and H, with some O and P
Elements of Life- Lipids
• Cell membranes consist mainly of phospholipids– These compounds contain a non-polar lipid “tail”
end, and a polar “head” end consisting of a phosphate ion
– In water, phospholipids align to create a bilayer that is polar on the surfaces and non-polar in the interior
Cells and Levels of Organization
• Cells are the smallest unit of life that can act independently and have all of the characteristics of living things
– Eukaryotes: Membrane bound Nucleus and organelles- Plants, Animals, Fungi, protists
– Prokaryotes: No membrane bound organelles or nucleus. Typically single celled- Bacteria and Archaea
Cells and Levels of Organization
• In Eurkaryotes, matter is organized into increasingly complex levels that allow for more complex roles and functions.
• Atoms-> Molecules -> Macromolecules-> Organelles -> Cells -> Tissues -> Organs -> Organ Systems -> Organism
Questions ?