Houston Methodist Research Institute Biorepository CoreCore Director: Rajeev Singh, MD, MBA 713.441.0777 Email: rsingh2@houstonmethodist.org

Core Manager: Pam McShane713.441.2113 Email: pmcshane@houstonmethodist.org

6565 Fannin St., Suite F774Houston, TX 77030

houstonmethodist.org/biorepository

Houston Methodist Research Institute

6670 Bertner Avenue

Houston, TX 77030

houstonmethodist.org/research

HMRI Communications & External Relations | RICORE-017 | MM | DH |250 | 01.2015

The Houston Methodist Research Institute Biorepository Core is a large, general-purpose sample bank of solid tissue samples, blood, serum, plasma, and other body fluids for use by Houston Methodist researchers and their collaborators. All sample collection activities are conducted in a manner that will ensure patient confidentiality, accurate pathologic annotation, and high ethical standards before, during, and after sample collection.

SOUTH

MAIN

ST.

CAMBRIDGE ST.

M.D

. AN

DER

SON

BLV

D.

MOURSUND ST.

M.D. AndersonCancer Center

BERT

NER

AVE

.

BATES ST.

JOH

NSO

N A

VE.

McGovernCommons & Trevisio

UNIVERSITY BLVD.

DRYDEN RD.

JOHN FREEMAN BLVD.

St. Luke’sHospital

Texas Children’sHospital Texas

HeartInstitute

WILKINS ST.

E. CULLEN ST.

ROSS STERLING AVE.

MemorialHermannHospital

Garage1 LA

MAR

FLEM

ING A

VE.

Ben TaubGeneralHospital

BaylorCollege

of Medicine

Marriot

Garage7

Universityof TexasHealth &Science

HWY 288

HOLCOMBE BLVD.

BRAESWOOD BLVD.

SOUTHLOOP610

TAUB

LOOP

P

P

P

P

JonesTower

OutpatientCenter

P

P

FANNIN

ST.

FANNIN

ST.

RICEUNIVERSITY

SOUTH

MAIN

ST.

SOUTHGATE BLVD.

UNIVERSITYOF HOUSTON

N

R

SmithTower

Scurlock

FondrenBuilding

Tower

RiceBioscienceResearch

Collaberative

Texas Children’s Neurological

Research Institute

HiltonHoustonPlaza/

MedicalCenterA

A

METRORAIL

DRYDEN/TMC METRORAIL STATION

P PARKING

MAP LEGEND

FONDREN BUILDING

ACCOMODATIONS

R

A

MaryGibb Jones

Building

ResearchInstitute

Houston Methodist

SOUTH

MAIN

ST.

CAMBRIDGE ST.

M.D

. AN

DER

SON

BLV

D.

MOURSUND ST.

M.D. AndersonCancer Center

BERT

NER

AVE

.

BATES ST.

JOH

NSO

N A

VE.

McGovernCommons & Trevisio

UNIVERSITY BLVD.

DRYDEN RD.

JOHN FREEMAN BLVD.

St. Luke’sHospital

Texas Children’sHospital Texas

HeartInstitute

WILKINS ST.

E. CULLEN ST.

ROSS STERLING AVE.

MemorialHermannHospital

Garage1 LA

MAR

FLEM

ING A

VE.

Ben TaubGeneralHospital

BaylorCollege

of Medicine

Marriot

Garage7

Universityof TexasHealth &Science

HWY 288

HOLCOMBE BLVD.

BRAESWOOD BLVD.

SOUTHLOOP610

TAUB

LOOP

P

P

P

P

JonesTower

OutpatientCenter

P

P

FANNIN

ST.

FANNIN

ST.

RICEUNIVERSITY

SOUTH

MAIN

ST.

SOUTHGATE BLVD.

UNIVERSITYOF HOUSTON

N

R

SmithTower

ScurlockTower

RiceBioscienceResearch

Collaberative

Texas Children’s Neurological

Research Institute

HiltonHoustonPlaza/

MedicalCenterA

A

METRORAIL

DRYDEN/TMC METRORAIL STATION

P PARKING

MAP LEGEND

BIOREPOSITORY COREROOM F774, FONDREN BUILDING

ACCOMODATIONS

R

A

MaryGibb Jones

Building

ResearchInstitute

Houston Methodist

BIOREPOSITORYCORE

HOUSTON METHODISTRESEARCH INSTITUTE

Biorepository Core

The Houston Methodist Research Institute Biorepository Core has been harvesting and storing samples such as tissues, blood, serum, plasma, and other body fluids since the establishment of the Research Institute in 2004. The core is the custodian of diagnostic tissue blocks and slides from the Department of Pathology and Genomic Medicine. These are available for research use with appropriate patient consent.

Solid tissue samples for various diseases, including cancers, and samples of blood, serum, plasma, and other body fluids are stored in the core’s in-house and off-site secure freezers. The core also has legacy collections of cell lines, cells from diagnostic flow and HLA assays, and extracted DNA from patient samples.

Services

• Collection, processing and storage in a timely, quality driven manner of fresh, snap-frozen, solid tissues from surgical pathology specimens, and blood and other body fluids from patients

• Provision of relevant controls including normal solid tissues from same or other patients, and/or blood from healthy patients/volunteers

• Providing research protocol-specific collection, processing, and storage services for all types of biospecimens

• Paraffin embedding, Immunohistochemical and Hematoxylin and Eosin staining, and pathology review services provided in conjunction with Research Pathology service

• Maintenance of a clinical database with basic clinical data elements for all samples in the repository, and provision of basic data elements, like age/gender/diagnosis available to our scientific users while safeguarding protected health information

• In depth data elements can be provided to individual investigators with necessary IRB approvals

• Round-the-clock monitoring of freezers with adequate backup and disaster recovery protocols in place

• Current global bio-banking standards followed to ensure research relevance of stored specimens for both internal and external collaborative purposes

To our patients:

• Maintain highest ethical standards before, during, and after sample collection

• Ensure complete safeguard of patient privacy and confidentiality, at all times and under all circumstances

To our researchers:

• Timely provision of high quality specimens with relevant data annotation

• Help bank and process specimens as per study-specific protocols, including shipping and record keeping

Our Commitment

Houston Methodist Research Institute