Bioresponsive nanosensors in medical imaging

by Eyk Schellenberger

InterfaceVolume 7(Suppl 1):S83-S91

February 6, 2010

©2010 by The Royal Society

Types of imaging probes.

Eyk Schellenberger J. R. Soc. Interface 2010;7:S83-S91

©2010 by The Royal Society

Principle of fluorescent smart probes.

Eyk Schellenberger J. R. Soc. Interface 2010;7:S83-S91

©2010 by The Royal Society

VSOPs were originally developed for MR angiography.

Eyk Schellenberger J. R. Soc. Interface 2010;7:S83-S91

©2010 by The Royal Society

Superparamagnetic nanoparticles for sensing apoptosis.

Eyk Schellenberger J. R. Soc. Interface 2010;7:S83-S91

©2010 by The Royal Society

Principle of an activatable PSOP. (a) A model of a PSOP. Based on electrostatically stabilized VSOPs, the nanoparticles contain a 5 nm superparamagnetic iron oxide core (grey) coated with a

monomeric, anionic citrate shell (red).

Eyk Schellenberger J. R. Soc. Interface 2010;7:S83-S91

©2010 by The Royal Society

Time courses of in vitro activation of MMP-2/9-PSOPs by MMP-9.

Eyk Schellenberger J. R. Soc. Interface 2010;7:S83-S91

©2010 by The Royal Society