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BioS 220 Mendelian andMolecular Genetics
Lecture 1. Cells and Genes
Chapter 1
Overview of genetics and the course
Syllabus
Some housekeeping details
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Why Genetics?
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Fig. 1 Swarna (left) and Swarna-Sub1 (right) in a farmer's field
after 10 days of complete submergence with turb id water in
Uttar Pradesh, India. The photo was taken 27 days after the
water receded.
The contribut ion of submergence-tolerant (Sub1) rice varieties to food
security in flood-prone rainfed lowland areas in Asia. Ismail, Singh,
Singh, Dar, Mackill. 2013. Field Crops Research 152: 83 - 93
Scuba Rice : a case study
http://www.youtube.com/watch?feature=player_detailpage&v=shCHe1eAQoQ
http://www.youtube.com/watch?v=apWCqcury90
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Fig. 3 Yield of Samba Mahsuri and Samba Mahsuri-Sub1 after variable durations of
submergence in farmers fields. Data are from farmers in Uttar Pradesh, India, during the
wet season of 2011 ( n = 59).
Website for s\detailed stories of SUB1and accelerated genetic improvement of crops.
http://www.authorstream.com/Presentation/aSGuest10
8849-1136509-marker-assisted-breeding/
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0.001 mm
10 mm
Genetics asks:
Why are children like their parents?
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0.001 mm
10 mm
Genetics asks:
Why are children like their parents?
Why are children different from their parents?
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Tools of Genetic Analysis
Mutation
Crosses
Biochemistry
Cytology
DNA Structure
DNA
manipulation
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Gregor Mednel at
Augustinian Abbey, Brno, Bohemia
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I. Rules of inheritance (of genes)
a. are inferred from PATTERNS of gene
transmission from one generation to the next
b. are used, once known,to study nature and function of genes
to deduce individual genes properties
to predict offspring types
II. Biochemical study of gene function gives more
precise understanding of gene action.
GENETICS
Avery, 1944
Mendel, 1865
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Genetics: careful examination of CROSSES
Parent 1genes
traits
Parent 2
genes
traits
Mating
n offspring:1: genes / traits
2: genes / traits
3: genes / traits4: genes / traits
5: genes / traits
. . .
n: genes / traits
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DNA ----> RNA ----> PROTEIN
New fig 1-9 here!
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RNA ----> PROTEIN
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Note:
in week 1 (only),
we have three lectures
and no Discussion sections
?
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Where are TA Office Hours held?
A LC-A1
B SCE CafeteriaC BSB Cafeteria
D SLC Darwin
E BSB Cafeteria
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Where are my Wednesday Office Office Hours held?
A LC-A1
B SCE CafeteriaC BSB Cafeteria
D SLC Darwin
E BSB Cafeteria
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Where does class meet this Friday?
A No lecture, only disc. SectionsB LC-A1
C Giordanos
D BSB Cafeteria
E SES 250
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?
What should you always bring to class?
A Hat and Gloves
B Textbook
C Lecture notes
D i>Clicker remote
E C and D
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?
Have you completed General Chemistry(112/114 or 116/118)?
A Completed
B This semester
C Not yet
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?
Have you completed Organic Chemistry (232/234)?
A Completed
B This semester
C Not yet
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?
Have you completed Introductory Physics?
A Completed
B This semester
C Not yet
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?
Have you completed Bios 222 Cell Biology?
A Completed
B This semester
C Not yet
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?
Where are test answer keys posted?
A LC-A1
B SEL 3289
C SLE
D MBRB
E Addams Hall
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?
How many of your classes have used i>Clickers?
A None
B 1
C 2 or 3D 4 or 5
E More than 5
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BioS 220
An i>clicker remote isrequired for this course.
You can purchase it
through the bookstore.
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How will we
use the clicker? I pose questions on the screen during
lecture.
You answer using your i>clicker remote.
Class results are tallied.
I display a graph with the class resultson the screen.
We discuss the questions and answers.
You get 1 point for participating and 4for answering correctly)!
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How do you vote?
Turn on the clicker by
pressing the bottom On/Off button.
A blue Power light will
appear at the top of the
remote.
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How do you vote?
When I ask a question in
class (and start thetimer), select A, B, C, D,or E as your vote.
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How do you know your
vote was received?Check your Vote Status Light:
Green light = your vote was sent
AND received.Red flashing light = you need to vote
again.
Not sure you saw the light? Just
vote again.
Want to change your vote? You can
vote again as long as the timer is stillgoing.
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Registering your i>clicker
You can earn points for your i>clickerresponses [for participation and/oranswering questions correctly].
Until you register your i>clicker, yourresponses are tied to your clicker remote ID
(located on the back of your clicker), ratherthan to you.
When you do register, your previously
recorded voting responses will be assignedto you.
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Registeringyour i>clicker unit
1. Go to BlackBoard.2. Go to Bio 220.3. Under Tools:4. Enter your iClicker
serial number.
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Other tips If you bought a used clicker, replace the batteries.
Register your clicker by January 21.
Before using a new clicker for the first t ime, pull the
plastic tab out of the battery compartment.
Bring your clicker to class every day!
Make sure your remote is on when voting!
Check out www.iclicker.com for FAQs.
Contact [email protected] for help.