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Biotech Sell Side Research: A Retrospective Analysis January 2013 Mark G. Edwards Managing Director BiosciAdvisors.com

Biotech Sell Side Research: A Retrospective Analysis · PDF fileBiotech Sell Side Research: A Retrospective Analysis 250 Public Biotech Cos (2+ Reports per Co) 2,492 Sell Side Reports

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Page 1: Biotech Sell Side Research: A Retrospective Analysis · PDF fileBiotech Sell Side Research: A Retrospective Analysis 250 Public Biotech Cos (2+ Reports per Co) 2,492 Sell Side Reports

Biotech Sell Side Research:  A Retrospective Analysis

January 2013

Mark G. EdwardsManaging Director

BiosciAdvisors.com

Page 2: Biotech Sell Side Research: A Retrospective Analysis · PDF fileBiotech Sell Side Research: A Retrospective Analysis 250 Public Biotech Cos (2+ Reports per Co) 2,492 Sell Side Reports

Biotech Sell Side Research:  A Retrospective Analysis

250 Public Biotech Cos (2+ Reports per Co)

2,492 Sell Side Reports over 14 years

- Initiation of Coverage (IOC) Reports only(10+ pages each report)

- All reports between 1998 and 2011

Key Question: Which of These Biotech Initiation of Coverage Reports Reached Their Target Stock Price Within a Year?

BiosciAdvisors.com

Page 3: Biotech Sell Side Research: A Retrospective Analysis · PDF fileBiotech Sell Side Research: A Retrospective Analysis 250 Public Biotech Cos (2+ Reports per Co) 2,492 Sell Side Reports

65

122 132116 121

270

215

261

292

258

205

278

157

98-99 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011

Biotech Initiation of Coverage Reports by Year (N=2,492)

BiosciAdvisors.com

Page 4: Biotech Sell Side Research: A Retrospective Analysis · PDF fileBiotech Sell Side Research: A Retrospective Analysis 250 Public Biotech Cos (2+ Reports per Co) 2,492 Sell Side Reports

82

64

46

19 18

6 8 7

2-5 6-9 10-13 14-17 18-21 22-25 26-29 30+

# of Initiation of Coverage Reports for Each Biotech Company (N=250 biotech cos.)

BiosciAdvisors.com

Page 5: Biotech Sell Side Research: A Retrospective Analysis · PDF fileBiotech Sell Side Research: A Retrospective Analysis 250 Public Biotech Cos (2+ Reports per Co) 2,492 Sell Side Reports

135

112104 102 101 98 91

81 79 78 78 72

PiperMorgan Stanley

Rodman

UBSWells

FargoCredit S

uisse

ThinkEquity

Jefferie

s

Citiban

kJP M

organ

CowenRoyal

Bank of C

anad

aTop 12 Most Frequent Issuers of Biotech

Initiation of Coverage Reports

BiosciAdvisors.com

Page 6: Biotech Sell Side Research: A Retrospective Analysis · PDF fileBiotech Sell Side Research: A Retrospective Analysis 250 Public Biotech Cos (2+ Reports per Co) 2,492 Sell Side Reports

70 7063 60

52 50 47 45 44 4238

34 34 34 33 33

Deutsc

he BankCan

accord

CIBC

RothOppenheim

erBrean

Merriman

Pacific

Natexis

Prudential

PunkHam

brecht

William Blair

Merrill L

ynchWedbushUnterberg

BiosciAdvisors.com

Other Frequent Issuers of BiotechInitiation of Coverage Reports

Page 7: Biotech Sell Side Research: A Retrospective Analysis · PDF fileBiotech Sell Side Research: A Retrospective Analysis 250 Public Biotech Cos (2+ Reports per Co) 2,492 Sell Side Reports

39 38 38

33 33 32

27 26 25 25 24 24 24 23 23 23 23

Pantginis, Joseph

King, Michael

Tenthoff, Edward

Aschoff,

JonathanKan

tor, Jason

Farmer, G

eorge

Yang, Eun

Augustine, M

arkMcMinn,Rachel

Harr, S

tevenSonnier, J

ohnTo, A

lexRea

mes, A

aronJellin

ek, Derek

Chovav, Meira

vGelle

r, Matt

Werber, Y

aron

BiosciAdvisors.com

Most Prolific Authors of BiotechInitiation of Coverage Reports

Page 8: Biotech Sell Side Research: A Retrospective Analysis · PDF fileBiotech Sell Side Research: A Retrospective Analysis 250 Public Biotech Cos (2+ Reports per Co) 2,492 Sell Side Reports

Distribution of Stock Ratings by Period of Biotech Coverage Initiation

BiosciAdvisors.com

4Q08 - 2012 (N=728)2005 – 3Q08 (N=938)Pre-2005 (N=826)

Page 9: Biotech Sell Side Research: A Retrospective Analysis · PDF fileBiotech Sell Side Research: A Retrospective Analysis 250 Public Biotech Cos (2+ Reports per Co) 2,492 Sell Side Reports

PiperMorgan Stanley

Rodman

UBSWells

FargoCredit S

uisse

ThinkEquity

Jefferie

s

Citiban

kJP M

organ

CowenRoy

al Ban

k of Can

ada

Buy Neutral Sell

Distribution of Stock Ratings by Top 12 Most Frequent Issuers of Biotech Initiation of Coverage Reports

BiosciAdvisors.com

Page 10: Biotech Sell Side Research: A Retrospective Analysis · PDF fileBiotech Sell Side Research: A Retrospective Analysis 250 Public Biotech Cos (2+ Reports per Co) 2,492 Sell Side Reports

Pantginis, Joseph

King, Michael

Tenthoff, Edward

Aschoff,

JonathanKan

tor, Jason

Farmer, G

eorge

Yang, Eun

Augustine, M

arkMcMinn,Rachel

Harr, S

tevenSonnier, J

ohnTo, A

lexRea

mes, A

aronJellin

ek, Derek

Chovav, Meira

vGelle

r, Matt

Werber, Yaron

Buy Neutral Sell

BiosciAdvisors.com

Distribution of Stock Ratings by Most Prolific Authors of Biotech Initiation of Coverage Reports

Page 11: Biotech Sell Side Research: A Retrospective Analysis · PDF fileBiotech Sell Side Research: A Retrospective Analysis 250 Public Biotech Cos (2+ Reports per Co) 2,492 Sell Side Reports

Predicted % Change in $/Share Over 12 Month Period

BiosciAdvisors.com

Sell Rating (N=120)***Neutral Rating (N=537)**Buy Rating (N=1,835)*

* 99 w/o Target Price ** 128 w/o Target Price *** 12 w/o Target Price

Page 12: Biotech Sell Side Research: A Retrospective Analysis · PDF fileBiotech Sell Side Research: A Retrospective Analysis 250 Public Biotech Cos (2+ Reports per Co) 2,492 Sell Side Reports

BiosciAdvisors.com

What Percentage of Biotech Initiation of Coverage Reports Reached Their Target Stock Price Within a Year?

Analyst Buy Recommendations (N=1,645)

Page 13: Biotech Sell Side Research: A Retrospective Analysis · PDF fileBiotech Sell Side Research: A Retrospective Analysis 250 Public Biotech Cos (2+ Reports per Co) 2,492 Sell Side Reports

Key Question:  Which of These Initiation of Coverage Reports Reached Their Target Stock Price Within a Year?

Analysis of Buy Recommendations that met their Target Stock Price within a Year by Investment Bankby Research Analyst

Analysis of Buy Recommendations with a Target Stock Price at Least 40% Higher within a Yearby Investment Bankby Research Analyst

BiosciAdvisors.com

Page 14: Biotech Sell Side Research: A Retrospective Analysis · PDF fileBiotech Sell Side Research: A Retrospective Analysis 250 Public Biotech Cos (2+ Reports per Co) 2,492 Sell Side Reports

135

112104 102 101 98 91

81 79 78 78 72

51

29 3123 28 28 35 28 22

918 22

PiperMorgan Stanley

Rodman

UBSWells

FargoCred

it Suiss

eThinkEquity

Jefferie

s

Citiban

kJP M

organ

CowenRoyal B

ank of C

anada

# of ReportsMet Buy Target

How Often Did the Most Frequent IssuersOf Biotech IOC Reports Reach Their Buy Target Price?

BiosciAdvisors.com

IOC = Initiation of Coverage

Page 15: Biotech Sell Side Research: A Retrospective Analysis · PDF fileBiotech Sell Side Research: A Retrospective Analysis 250 Public Biotech Cos (2+ Reports per Co) 2,492 Sell Side Reports

70 7063 60

52 50 47 45 44 4238

34 34 34 33 3325 28

18 19

916 14 15 13 14 12 15

39

159

Deutsc

he BankCan

accord

CIBC

RothOppenheim

erBrean

Merriman

Pacific

Natexis

Prudential

PunkHam

brecht

William Blair

Merrill L

ynchWedbushUnterberg

# of ReportsMet Buy Target

BiosciAdvisors.com

How Often Did Other Frequent Issuers of Biotech IOC Reports Reach Their Buy Target Price?

IOC = Initiation of Coverage

Page 16: Biotech Sell Side Research: A Retrospective Analysis · PDF fileBiotech Sell Side Research: A Retrospective Analysis 250 Public Biotech Cos (2+ Reports per Co) 2,492 Sell Side Reports

39 38 38

33 33 32

27 26 25 25 24 24 24 23 23 23 23

16

1115

11 1013

79

7 7

1

12

37

97 7

Pantginis, Joseph

King, Michael

Tenthoff, Edward

Aschoff,

JonathanKan

tor, Jason

Farmer, G

eorge

Yang, Eun

Augustine, M

arkMcMinn,Rachel

Harr, S

tevenSonnier, J

ohnTo, A

lexRea

mes, A

aronJellin

ek, Derek

Chovav, Meira

vGelle

r, Matt

Werber, Yaron

# of ReportsMet Buy Target

BiosciAdvisors.com

How Often Did the Most Prolific AuthorsOf Biotech IOC Reports Reach Their Buy Target Price?

IOC = Initiation of Coverage

Page 17: Biotech Sell Side Research: A Retrospective Analysis · PDF fileBiotech Sell Side Research: A Retrospective Analysis 250 Public Biotech Cos (2+ Reports per Co) 2,492 Sell Side Reports

The Best Sell‐Side Biotech Stock Pickers Over the Past Decade Are …

Among the Most Frequent Issuers of Coverage, Piper and ThinkEquity each met their Buy Target Price in 38% of their Biotech IOC Reports

Among the Other Frequent Issuers of Coverage, Wedbush, Hambrecht and Canaccord met their Buy Target Price in at Least 40% of their Biotech IOC Reports

Among the Most Prolific Authors of Coverage, Alex To (of Natexis, previously at Credit Suisse) met his Buy Target Price in 50% of his IOC Reports

BiosciAdvisors.com

Page 18: Biotech Sell Side Research: A Retrospective Analysis · PDF fileBiotech Sell Side Research: A Retrospective Analysis 250 Public Biotech Cos (2+ Reports per Co) 2,492 Sell Side Reports

BiosciAdvisors.com

What Percentage of Biotech Initiation of Coverage Reports Reached Their 40+% Gain Target Stock Price Within a Year?

Analyst 40+% Gain Buy Recommendations (N=987)

Page 19: Biotech Sell Side Research: A Retrospective Analysis · PDF fileBiotech Sell Side Research: A Retrospective Analysis 250 Public Biotech Cos (2+ Reports per Co) 2,492 Sell Side Reports

84 83 73 79 73 70 56 53 57 69 60 50

3013

817 17 16

24 17 146 12

13

21

16

96381111

23 6 1211

PiperMorgan Stanley

Rodman

UBSWells

FargoCred

it Suiss

eThinkEquity

Jefferie

s

Citiban

kJP M

organ

CowenRoyal B

ank of C

anada

40%+ Gain<40% GainOther Reports

How Often Did the Most Frequent IssuersOf Biotech IOC Reports Reach a Target Price of 40%+ Gain?

BiosciAdvisors.com

IOC = Initiation of Coverage

Page 20: Biotech Sell Side Research: A Retrospective Analysis · PDF fileBiotech Sell Side Research: A Retrospective Analysis 250 Public Biotech Cos (2+ Reports per Co) 2,492 Sell Side Reports

45 42 45 41 4334 33 30 31 28 26

1931 25

18 24

18

7 5 8 37 8 8 9 9

46

37

2

7

2132098

547696

1113

217

Deutsc

he BankCan

accord

CIBC

RothOppenheim

erBrean

Merriman

Pacific

Natexis

Prudential

PunkHam

brecht

William Blair

Merrill L

ynchWedbushUnterberg

40%+ Gain<40% GainOther Reports

BiosciAdvisors.com

How Often Did the Other Frequent IssuersOf Biotech IOC Reports Reach a Target Price of 40%+ Gain?

IOC = Initiation of Coverage

Page 21: Biotech Sell Side Research: A Retrospective Analysis · PDF fileBiotech Sell Side Research: A Retrospective Analysis 250 Public Biotech Cos (2+ Reports per Co) 2,492 Sell Side Reports

2327

23 22 2319 20 17 18 18

23

1221

16 14 16 16

2

87 6 4

5 34 4 1

0

6

3

3 6 1 4

3630 4616354

865

8314

Pantginis, Joseph

King, Michael

Tenthoff, Edward

Aschoff,

JonathanKan

tor, Jason

Farmer, G

eorge

Yang, Eun

Augustine, M

arkMcMinn,Rachel

Harr, S

tevenSonnier, J

ohnTo, A

lexRea

mes, A

aronJellin

ek, Derek

Chovav, Meira

vGelle

r, Matt

Werber, Yaron

40%+ Gain< 40% GainOther Reports

BiosciAdvisors.com

How Often Did the Most Frequent AuthorsOf Biotech IOC Reports Reach a Target Price of 40%+ Gain?

IOC = Initiation of Coverage

Page 22: Biotech Sell Side Research: A Retrospective Analysis · PDF fileBiotech Sell Side Research: A Retrospective Analysis 250 Public Biotech Cos (2+ Reports per Co) 2,492 Sell Side Reports

… And When Swinging for the Fences, Best Sell‐Side Biotech Stock Pickers Over the Past Decade Are …

Among the Most Frequent Issuers of Coverage, Rodman Predicted and Got a 40+% Gain in 22% of their Biotech IOC Reports

Among the Other Frequent Issuers of Coverage, Wedbush & Canaccord Predicted and Got a 40+% Gain in 39% and 30% of their Reports, Respectively

Among the Most Prolific Authors of Coverage, Joseph Pantginis (of Roth, previously at Merriman and Canaccord) Predicted and Got a 40+% Gain in in 36% of his Biotech IOC Reports

BiosciAdvisors.com

Page 23: Biotech Sell Side Research: A Retrospective Analysis · PDF fileBiotech Sell Side Research: A Retrospective Analysis 250 Public Biotech Cos (2+ Reports per Co) 2,492 Sell Side Reports

Next Question:  What is the Sweet Spot for Biotech Analysts to Meet their Target Stock Price Within a Year?

Analysis of All Biotech IOC Recommendationsby Biotech Stage of Developmentby Biotech Therapeutic Area

Analysis of 40+% Buy Recommendationsby Biotech Stage of Developmentby Biotech Therapeutic Area

BiosciAdvisors.com

Page 24: Biotech Sell Side Research: A Retrospective Analysis · PDF fileBiotech Sell Side Research: A Retrospective Analysis 250 Public Biotech Cos (2+ Reports per Co) 2,492 Sell Side Reports

BiosciAdvisors.com

Until a Biotech Product is on the Market, the Odds Are Against an Analyst Hitting their Stock Recommendation

Phase II Phase III NDA Filed Market

Target Price Not ReachedTarget Price Reached

Page 25: Biotech Sell Side Research: A Retrospective Analysis · PDF fileBiotech Sell Side Research: A Retrospective Analysis 250 Public Biotech Cos (2+ Reports per Co) 2,492 Sell Side Reports

BiosciAdvisors.com

Infection is the Therapeutic Area Where Analysts are Most Likely to Hit their Stock Recommendation

Infection OncologyCardiovascularCNS

Target Price Not ReachedTarget Price Reached

Page 26: Biotech Sell Side Research: A Retrospective Analysis · PDF fileBiotech Sell Side Research: A Retrospective Analysis 250 Public Biotech Cos (2+ Reports per Co) 2,492 Sell Side Reports

BiosciAdvisors.com

For Buy Recommendations of 40+% Price Gain, Even Products on the Market Make for a One in Three Bet

Phase II Phase III NDA Filed Market

Target Price Not ReachedTarget Price Reached

Page 27: Biotech Sell Side Research: A Retrospective Analysis · PDF fileBiotech Sell Side Research: A Retrospective Analysis 250 Public Biotech Cos (2+ Reports per Co) 2,492 Sell Side Reports

BiosciAdvisors.com

For Buy Recommendations of 40+% Price Gain, Infection is Still the Best Therapeutic Area Bet 

Infection OncologyCardiovascularCNS

Target Price Not ReachedTarget Price Reached