Blood components

Making blood activityInquiry resource

Disturbing?

Components of Blood

Blood

• average 4-5L in a human body• Blood is a connective tissue• When centrifuged, blood separates into two

major components:• Plasma(55%)• Formed elements (45%)

Blood’s components1. Plasma•Fluid part of the blood

–92% water–1% ions (Ca 2+, Na+, K+, Cl-, etc.)–7 % proteins (albumins, globulins, fibrinogen)Serum = plasma –( fibrinogen +clotting factors)

2. Cellular components (also Formed elements): RBC, WBC, and platelets

To fill in the info on slide 13-17; use the provided summary table on Cellular component of blood.

Your table should look like the page on the right here

Description FunctionRed Blood Cell (erythrocytes_)99% of Cellular Components

tiny biconcave disks (135 RBC = 1mm). Biconcave shape increases surface areaCan fold to pass through narrow blood vesselsMade from stem cells in bone marrowLack mitochondria and nucleiStored in spleenConstantly being destroyed and replaced (~120 days)

Carry O2 & CO2Have iron-containing protein called hemoglobin (~ 280 mill/1 RBC) specializing at transporting O2 1 hemoglobin can bind 4 O2Anemia are conditions of haemoglobin shortage

2. Cellular Components (previously called Formed elements)

White Blood Cell (Leucocytes)

Produced in the bone marrowDo have nuclei5-9 mill./1cm3 of bloodMale 10% more WBC than femaleMany different types1. Neutrophils2. Basophils3. Eosinophils4. Lymphocytes5. Monocytes

• Defend against diseases and infections

• Function in allergic reactions

• Produce antibodies stimulated by binding of foreign particles

• Phagocytize (i.e. engulf) to destroy invaders

• Leukemia – cancer of the wbc (wbc can’t stop dividing)

2. Cellular Components of Blood (Cont)

Pus

WBC

Histology of WBC

2. Cellular Components of Blood (Cont)

Platelets (thrombocytes)

Fragments of cells 1-3um; no nucleiBreak down after 7-10 days

Responsible for blood clottingPrevent excessive blood lossHemophilia – Sex-linked condition resulting in excessive bleeding

How blood clots? https://www.youtube.com/watch?v=--bZUeb83uU

Let’s go to the ER: https://www.youtube.com/watch?v=cFmmmj6a2sY

Consolidation- HWBlood component summary table